Text-book of comparative anatomy . e of calcareous deposits in theintercellular substance. Cartilaginous tissue, on account of its firmness, serves as support-tissue in vertebrate and in someinvertebrate animals. Bone tissue forms, pat- excellence,the supporting tissue of vertebrates.The intercellular or bone substancebecomes as hard as stone by a com-bination of lime-salts with some groundsubstance, which yields glue on beingboiled, and does not dissolve undertreatment with acids. In it are scatteredthe cell elements (bone cells) ; they aremuch branched, and connected by their processes ; the

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Text-book of comparative anatomy . e of calcareous deposits in theintercellular substance. Cartilaginous tissue, on account of its firmness, serves as support-tissue in vertebrate and in someinvertebrate animals. Bone tissue forms, pat- excellence, the supporting tissue of vertebrates.The intercellular or bone substancebecomes as hard as stone by a com-bination of lime-salts with some groundsubstance, which yields glue on beingboiled, and does not dissolve undertreatment with acids. In it are scatteredthe cell elements (bone cells) ; they aremuch branched, and connected by their processes ; they are arranged inparallel layers, often concentrically round the cavity (Fig. 44). Bonetissue arises out of indifferent connective tissue cells, which are arrangedin strands or flat expanses, and which function as formative cellsof the bone tissue, osteoblasts (Fig. 45, a). They produce on one sidebone substance, often in the direction of cartilaginous masses, whichthey supplant, at the same time forming processes which remain im-. .:.-u, ;;-£^ FIG. 43.—Fibrous cartilage, after Glaus.