Thousand Plants against Cancer without Chemo-2010(1)

Giuseppe Nacci , M.D.Thousand Plantsagainst Cancerwithout Chemo-TherapyMay 2010650 pagesEVIDENCE BASED MEDICINE:2,050 official scientific publications2,100 various bibliographical referencesFrom:“Mille Piante per guarire dal Cancro senzaChemio” book –on line(http://www.erbeofficinali.org/dati/nacci/index.phphttp://aloearborescens.tripod.comhttp://www.mednat.org/Nacci%20libro.pdfhttp://www.medicinetradizionali.it/nacci.htm1

Everyone is allowed to diffusethis book, in its paper versionand/or digital format(CD-ROM or INTERNET),with no view to profit.2

If the people let the goverment decide what foods they eat and whatmedicines they take, their bodies will soon be in as sorry a state as thesouls who live under tyranny.Thomas JeffersonUnless we put medical freedom into the Constitution, the time will comewhen medicine will organize into an undercover dictatorship.To restrict the art of healing to one class of men and deny equal privilegesto others will constitute the Bastille of medical science.All such laws are un-American and despotic and have no place in arepublic. The Constitution of this republic should make special privilegefor medical freedom as well as religious freedom.Benjamin Rush, M.D.(George Washington’s personal physician and signer of the Declaration of Independence)3

The Two Presidents…..From People,With People,For PeopleAbramo LincolnYes, We canBarack Hussein Obama4

DEDICATION…….…Dr Max Gerson dedicated his life to the mastery of this scourge ofcancer and all should honor his great work…The Honorable United States Senator Claude Pepper (D-Florida)..... Cancer is not cured with surgical instruments, but with a vegetariandiet and medicinal herbs…Hippocrate of KosLet your food be your medicine and your medicine be your food….Hippocrates of Cos…Very often the simple truth is absolutely not believed ;You can recover from Cancer but not from Chemotherapy:Out of FIFTY people suffering from cancer who decide toundergo CHEMOTHERAPY, only ONE will be still aliveafter only FIVE years from the first Chemotherapy cycle….the Author5

….E Noi dovrem, ahimè, morir….Morir….Dilegua o Notte……Tramontate Stelle……Tramontate Stelle…All’Alba vincerò……vincerò…vincerò !Luciano Pavarottihttp://it.youtube.com/watch?v=VATmgtmR5o46

Article No. 11 of the of Declaration of human and civic rights (France, 1789):“The free communication of ideas and opinions is one of the most precious rights ofthe man: any citizen may therefore speak, write and publish freely”.Article No. 19 of the Universal Declaration of Human Rights (UNO, 1948):“Everyone has the right to freedom of opinion and expression; this right includesfreedom to hold opinions without interference and to seek, receive and impartinformation and ideas through any media and regardless of frontiers”.Article No. 2 of the Italian Constitution:“Everyone has the right to freely express thoughts in speech, writing and by othercommunication. The press may not be controlled by authorization and submitted tocensorship”.Article No. 11 of the EU Charter of Rights (2000):“Everyone has the right to freedom of opinion and expression; this right includesfreedom to hold opinions without interference and to seek, receive and impartinformation and ideas through any media and regardless of frontiers”.Medical ethics and freedom to consciously choose a therapy(article No. 32 of the Italian Constitution):”The Republic protects individual health as a basic right and in the public interest; itprovides free medical care to the poor.Nobody may be forcefully submitted to medical treatment except as regulated by law.That law may in no case violate the limits imposed by the respect for the humanbeing”.7

Note: Scientific references:In this book the plants are identified by their Latin names –according to the modern scientific classification (see Chapter 20)– and 2,050 official scientific publications are quoted (out of 2,100various bibliographical references (see Chapter 21), useful to indepthstudies, which confirm the various arguments indicatedhere.8

Thousand Plants against Cancerwithout Chemo-TherapyEd. 2010INDEXDEDICATION…………………………………………………………………………………….5INDEX…………………………………………………………………………………………….9INTRODUCTION………………………………………………………………………………..20The case of the “LAETRILE” (Vitamin B17) ……………………………………………………23The Metabolic Therapy…………………………………………………………………………….27Chap. 1 : Food ……………………………………………………………………………………..35Chap. 1.a: CARBOHYDRATES ………………………………………………….……………….36Chap.1.b: PROTEINS…………………………..………………………………………………….42Intestinal DISBIOSIS…………………………………….…………………………………………44Asthma, allergies and food intolerances……………………………………………………………46Autoimmune diseases…………………………………………….…………………………………46Malignant tumours…………………………………… …..……..…………………………………47Other diseases ……………………………………………………………………….……..……….47Altered impermeability of intestinal walls…………………………………….…….…….………..47Chap. 1.c: FATS and OILS (“Fatty acids”)………………………………………….……..………48Chap. 1.d: VITAMINS……………………………...…………………………..………….………50VITAMINS (In alpahabetic order):………………………….…………………….………..………53Chap 1.2: “Herb-Therapy must not be prohibited” ……………………………..…………………55Europe First To Ban Supplements…………………………………..………………………………57Chap. 2: The ideal diet for cancer therapy………………………………………...………..………59Chap. 2.2.: Food combinations (cereals + legumes)……………………………...……….……….59Chap. 2.3.: The dangers of GM food ………………………………………………………………609

Chap. 2.4.: The importance of oils…………..…………………………………………………62Chap. 2.5.: Spices, grass used in cooking but also in medicine…………..……………………62Chap. 2.6: The Pulses………………………………….…..…………………………………..63Chap. 2.7.: Dried fruit …………….…………….……….…………………………………….64Chap.2.8.: breakfast, Lunch and dinner……….………………………………………………..64Chap.2.8.a: Useful breakfast in the morning……………………………………………………64Chap. 2.8.b.: During the morning……………………………………………………………….65Chap. 2.8.c: When you cook vegetables ………………….……………………………………65Chap.2.8.d.: Pickled vegetables……………………………..…………………………………..65Chap.2.8.e.: Exotic fruit…………………………………………………………………..……..65Chap.2.8.f.: Drinking water…………………………...…………………………………………65Chap.2.8.g.: Lunch and/or dinner: The importance of cereals ………………………………….66Chap.2.9.: Fish……………………………………….…………………………………………..67Chap.2.10.: Sugars………………………………………….…………………………………….67Chap.2.11.: Salt……………………………………………….…………………………………..67Chap.2.12.: Toxic or dangerous food……………………………………………………………..67Chap.2.13.: Food that is dangerous for health if consumed often:……..…………………………68Chap.2.14.: The problem of bread…………………………………………………………………68Chap.2.15.: The GMO dangerous (SEE also below in another pages)……………………….…….69Chap.2.16.: Domestic pollution…………………………………………………………..………70Chap. 2.17.: the problem of the labels of food wrappings…..…………………..…………………72Chap. 2.18: Conventional agriculture (or chemical agriculture, or industrial agriculture)…….….73Chap. 2.19 : Organic farming and small-scale retail trade ……………………………….….…..…75Author's considerations of Organic Farming………………………………..……………..………..76Chapter 2.20 The latest deception: Marker Assisted Selection (MAS).When genetic deception returns to farmers’ fields through HYBRID plants………………………7810

Chap.2.21.: From hybrid plants to GMO TERMINATOR plants…………………………………..81Chap.2.22.: The Threat of Genetically Modified Organisms………………………………………..81Chap.2.23.: Allert G.M.O.: The USA are passing a law that legalizes the contamination of cropswith genetically modified organisms (GMO). Source: Friends of the Earth International(DECEMBER 2004) ………………………………………………………………………………..88Chap.2.24.: RUSSIA, GM Food Dangers Directly Affect Biological Descendants and FutureGenerations…………………………………………………………………………………………..88Chap. 2.25.: GMO–Terminator: the new threat……………………………………………………89Chap. 2.26.: How the European Union destroys the European Agriculture……….………………..91Chap. 2.27.: Effects of European rules concerning the size of fruit and vegetable markets onagricultural production………………………………………………………………………………92Chap. 2.28.: Brussels bureaucracy authorizes parasitical revenues………………...……….……….93Chap. 2.29.: Obstacles in the way of the Direct Sale from Producers to Consumers………...……...93Chap. 2.30.: The Non GMO Project (USA)…………………..……………………………..………94Capther 3 : Anti-oxidative nutrition ………………………………………………….……………96Chap. 3.a.: Retinoids and Carotenoids………….…………...………………..……….……………98Chap. 3.b: Camellia sinensis (green tea)………………………………………..…………...…….101Chap. 3.c.: Vitamin C……………………………………..........……..…………………….…..…102Chap. 3.d: Vitamin D…………………………………………..…………………………..………104Chap. 3.e: Vitamin E (alpha-Tocopherol)……………………….…………...……………………105GMO multinationals are modifying the contents of Tocopherols…………………………………106Chap. 3.f: vitamin F……………………………………….………………………………… . …..107Chap. 3.g : Organic Germanium Ge 132……………………………………………………..……111Organic and inorganic forms of Germanium………………………….............……………..……111Natural organic Germanium……………………………………………………………..…..…….111The immune stimulating properties of organic Germanium……………………..……..…..……..111Anti-oxidant property of organic Germanium………………………………….………………….111Anti-ischemic properties of organic Germanium………………………………………………….11211

Modifications of the biochemical and functional parameters of the organism induced by organicGermanium……..…………………………………………………………………………………113Anti-amyloidosis property of organic Germanium……………………….……………………….113Analgesic property of organic Germanium…………………………………………………....…..113Chap. 3.h: Garlic (Allium sativum)……………………………………..…………………………114Chap 3.i.: Silybum marianum (milk thistle)……………………………….………..…………….122Chap. 3.l: Lycopene…………………………………………………………………..…………..123Chap. 3.m: organic acids…………………………………….……………………..……………..124Chap. 3.n: Hippocrates Soup……………………………………….………………..……………124Chap. 3.o: Organic Zinc…………………………………………….……………….……………125Chap. 3.p: Honey ...........................................................................................................................126Chap. 3.q: other anti-oxidative phyto-medicines……………………………………..…………..128.Chap. 4 : Phyto medicines with anti-infection activity………………….………………………..132Chap. 5 : Phyto-medicines with an anti-uricemic activity ……………………………………….137Chap. 6 : Phyto medicines with a Bio-Chemo-Therapy action: plants which have a “suicide affect”on Cancer………………………………………………………………..………………………..139Chap. 6.a : the plants…………………………………………………………………………….141Chap. 6.b.: The perverse alliance of the agro-industrial and chemical-pharmaceuticalMultinationals……..………………………………………………………………………………148Chap. 6.c………………….………………………..…………………………………..…………152Note : Selective inhibitions on telomere activity………………………………..……..…………153Chap. 6.d: The berries of Pittosporum tobira and Chamaerops excelsa…………………………..154Chap. 6.e : Limonene……………………………………………..…………………………..……155Chap.6.f: Elemene………………………………………………………………………….……..156Chap. 6.g: Other phyto-medicines with an apoptotic or pseudo apoptotic activity…….……...…..156Chap. 7 : vitamin B 17 (Laetrile)…………………………………………………………….…….167Allegated: Morrone J.A.: Preliminary Report of 10 cases treated with Laetrile…………………17512

Allegated: Clinical Trial of Chemotherapeutic treatment of advanced cancers with Leatrile (L-Mandelonitrile-Beta-Diglucoside)…………………………………………………………………174Amygadin metabolic liver aspects………………………………………………………...……….175Amygdalin poisoning: medical aspects…………………….………………….……………..……177Chapter 8: Retroviruses and Cancer………………………………………………………...……..181RNA tumour VIRUSES (Oncornaviruses)……………………………………….………..………182Reactions of Oncornaviruses to chemical and physical agents………..………………………….183Antigenic properties of Oncornaviruses……………………………………………..……………183Oncornavirus replication and cell transformation………………..……………….………….184Oncornavirus – induced tumours………………………………….……………………..……184Complex A [Complex of avian leukaemia – avian sarcoma]…………………………………185Complex B [Complex of murine leukaemia- murine sarcoma]……………………………..…….186Complex C [Complex of the murine mammary tumour (carcinoma)]…...…..…….………...……187Complex D [Complex of feline leukaemia- feline sarcoma]……….………………………...……188Complex E [Primate Oncornavirus]………………………………….……………………..……..189Other Retro-viruses……………………………………….…………..…………………..……….189Chap. 8.2.: Dangers Inherent in the Process Itself - THE USE OF CAULIFLOWER MOSAICVIRUS……………………………...…………………………………..…….……………………190Chap. 8.3.: Scentific Article in WEB (UNDER : Retro virus and Cancer )……………..………...193Chapter 9: Immune Therapy………………………………………….……………………………1969.a : Immune stimulation : the experience of S.A.Rosenberg…………………………….……….199Chapter 9.b : Aloe arborescens……………………………….……………………..………….….200Chapter 9.c : ESSIAC…………………………………………………………….………………..203Chapter 9. d : Other plants with an immune stimulating activity…………………………………208Chap. 9.e.: Anti-cancerous plants or similar plants with immune stimulating properties, mentionedin Herbario Novo………………………………………………………………..…….…………..223Chap. 9.f.: Adjuvant immuno-therapy: Phyto medicines with an anti-stromal action on connectivecancer tissue……………………………………………………………………………………….22613

Chapter 9.g: The HOXSEY Therapy…………………………………………..…………………..228Chapter 9.h : Coley's toxins………………………………….……………..……………….……..234Chapter 9.i : Bonifacio’s Serum…………………………………………..……………..……….234Chapter 9.l.: Lectins…………………………………………….………….…………..………….235Chap. 10: Non-insulin-dependent Diabetes mellitus or adult diabetes……………………..……..236Chap. 10.1.: Modifications to the diet…………….………………………..……………..……….237Vitamin C deficiency and the threat of Statins……..………………………………………...……240Marginal note: Diabetes and the grave threat of Genetically Modified Organisms……..……..….241Chap. 10.2.: Oral hypoglycaemic drugs………………………………………………….…..……243Chap. 10.5.: Healing with Gerson-like diet………………………………………………………..244Chapter 11 Multiple Sclerosis (or Sclerose en plaques)……………………………….………….245Chap. 11.1.: Multiple Sclerosis Etiopathogenesis and Therapy According to C. Kousmine…...…245Chap. 11.2.: Etiopathogenesis and Therapy for MS Developed According to a Neurologist of theUniversity of Oregon Health Sciences Center in Portland……………………………….….…....246Chap. 11.3.: Personal Clinical Cases…………………………………………………….……..….247Chap. 12: Tamoxifen and natural phytoestrogens……….………………………………..……….249Chapter 13: Neurological diseases, cardiovascular diseases and ageing…………..………………251Chap. 13.1.: Ageing……………………………………..…………………………………………252Telomeres and ageing……………………………………….………………………………..……252Other ageing factors……………………………………………..…………………………….…..253Chap. 13.2.: Cardiovascular Diseases……………………………………………………………..254Chap. 13.3.: Emergency Medicine……………………………………………..………………….255Chap. 13.4.: The Failure of the Cronos Study on Alzheimer………………………………...……256Chap. 13.5.: The common fallacy that cholesterol is bad, the truth about vitamin C deficiency andthe pharmaceutical issue of Statins……………………….………..……………………………..257The threat of statins…………………………………………...…………………………………..257Commercial interest in developing statins………………………………………..……………….25714

Chap. 14: Scientific bases of an ANTI-CANCER therapy on a dietary and multivitaminic basis .258Using energizing substances ...............................................……………………………….……..262Chap. 14.1: Clinical Aspects, Instrumental Data and Laboratory Values/Results……………….264INFLAMMATIO LYMPHONODIS (Inflammation of the lymph nodes)…………..…………..264INFLAMMATIO TUMORIS: ……….………………………………………………..……….…265FUNCTIO LESA: ……………………………………………………………………..……….…266DEPROTEINATIO TUMORIS ………………….…………………………………..………. 266RELIQUATIO TUMORIS…………………………………………….………………..…………267EXPURGATIO TUMORIS…………………………………………………………..……………268RESOLUTIO PARTIALIS TUMORIS …………………………………..…………..……..……268RISOLUTIO TOTALIS TUMORIS …………………………………….…………..……..……268OBSERVATIONS………………………………………………………..………….……………269Chap. 14.2: Using phyto-medicines with anti-inflammatory activity……………….……….…..274Chap. 14.3: Detoxification of the ill organism………………………………………..………….276Chap. 14.3.a: The usefulness of Potassium for human metabolism……………………….……..280Chap. 14.3.b: Potassium supplementation on the Gerson Therapy………………………………282Chap. 14.3.c.: Potassium compound for one’s enema solution…………………………..………283Chap. 15: Phytotherapics with antiangiogenesis action …………………………………………285Chap. 16: Based-Protocol of Dr Giuseppe Nacci (M.D.), for Cancer Therapy...............................287Some Juicing tips offered previously by Dr. Gerson……..……………………………………….298Chap. 17: Absolute incompatibility of Phyto-Therapy with Chemo-Therapy…………………….303Chap. 17.1.: the failure of the Chemio-Therapy…………………………………………………..306When Chemotherapy is useful……………………………………..………..……………….……307The Dubious Validity of Official Statistics ………………………………….………………….307Cost of Chemotherapy…………………………………………………………………………….30815

Chap.17.2.: Official statistics of Chemo-Therapy……………………………..………………..309Brain Tumours……………………………………………………………………………………309Head and Neck Cancers………………………………………………………………………….309Non-small Cell Lung Cancer…………………………………….………………………………..310Small-cell Bronchial Carcinoma ………………………………………………………………….310Breast cancer………………………………...…………………………………………………….311Cancer of the Stomach …………………………………………………………………………….313Cancer of the Pancreas…………………………………………………………………………….315Kidney cancer…………………………………………………………...…………………………316Cancer of the Prostate……………………………………………………………………………..316Ovarian Cancer…………………………………………………………………………………….317Cancer of the Uterus and Endometrium……………..……………….……………………………317Colorectal Cancer……………………………….………..………………………………………..317Chronic Lymphocytic Leukaemia………………………………..……………….……………….318Acute Lymphoblastic Leukaemia in Adults………………………....…………………………….318Acute Lymphoblastic Leukaemia in Children ……………………………………………………319Chronic Myelogenous Leukaemia…………………………….…………………………….…….319Acute Myelogenous Leukaemia…………………………………...……………………….……..319Multiple Myeloma………………………………………………………………………….…..…320Hodgkin’s Lymphoma…………………………………….………………………………..…..…320Non-Hodgkin’s Lymphoma……………………………………………………………………….322Conclusion……………………………………………………………………………………...….323QUESTIONS to ask your DOCTOR………………………………………………………….…...325Chapter 18: Dangerous Plants……………………………………………………………………..327Chap. 18.1.: Plants that are potentially efficient against tumors, but whose heavy side-effects arealready known or suspected in their use………………………………………………………..…32716

Chap. 18.2.: Plants to Absolutely avoid using………………………………………….…………329Chap. 18.3.: Families of dangerous or prohibited plants:…………………………………..……..332Chapter 19: The Law of the Rommunes………………………..…………..…………………….333Chap. 20 NAMES OF PLANTS of medical interest that have or have not been mentioned in theprevious text……………………….………………………………………………………………340Chap. 21: Bibliography………………………………………………………….…………...……367Curriculum vitae of the author…………………………………………………………………….43417

ALLEGATEDsALLEGATED No. 1: The Case for a GM-free Sustainable World ……………………………………..…………….437ALLEGATED No. 2: Article by AGNES SINAI Researcher……….……………….………..……………………….443ALLEGATED No. 3 : Mexican Clinics …………………………………………………………..……….…………..447List of other Clinics in Center/South AMERICA Offering Alternative Therapies………………………….….………450List of Clinics in the United States Offering Alternative Therapies………………………………….………..……….452List of Clinics in CANADA Offering Alternative Therapies……………….………………………………..…..……..466List of Clinics in EUROPE Offering Alternative Therapies……………………………………………..….....……….468List of Clinics in ASIA / OCEANIAOffering Alternative Therapies…………..………………………………………473ALLEGATED No. 4 : Emodine-Aloe………….………………………………………………………………….…..474ALLEGATED No. 5: Sherry Rogers, M.D.: The World's Most Vicious MACC Attack(MACC - multinational agriculture and chemical corporations)………………………...…………………...…..……485ALLEGATED No. 6: Official list of authorized GMOs in Europe………………………………..……………...…….489ALLEGATED No.7: Poverty and globalisation by Vandana Shiva …………………………….…..…….………….491ALLEGATED No. 8: Phyto-Therapy (Plant therapy) is a classical medical therapy, NOT an alternativetherapy……………………………………………………………….…………………………………..……….……..500ALLEGATED No. 9: Open Letter to the Government…………………………………….……………………………503ALLEGATED No. 10 : November 2005: The last letter from America……………………………………….……….504ALLEGATED No. 11 :The importance of a Healthy and Self-sufficient Agriculture…………………………………………………………....506ALLEGATED No. 12: Jason Vale : an American Hero………………………………………..………………..……..507ALLEGATED No. 13: Joe Cummins and Mae-Wan Ho : Hazards of CaMV Promoter………………………….….516ALLEGATED No. 14: Mae-Wan Ho : Recent Evidence Confirms Risks of Horizontal Gene Transfer ………….….518ALLEGATED No. 15: GM crops increase pesticides………………………………………………………...………..52318

ALLEGATED No. 16:American Academy of Environmental Medicine. OGM : A Moratorium on Gentically Manipulated (GMO) Food(22/5/2009)……………………………………………………………….………………………………………….….525ALLEGATED No. 17:SANA Conference – Bologna 2008, 13 th September, Promoted by: AAM Terra Nuova, Scientific coordination: StudioAgernova Dr. Giuseppe Nacci : “The Threat of GMOs (Genetically Modified Organisms) on alimentary modelsaccompanying the immune and detoxifying therapy” ………………………………………………………………..528ALLEGATED No. 18:SANA (Bologna) 13 /9 / 2008, Aprobado por: AAM Terra Nuova, Coordinamiento Científico: Studio Agernova,Doctor Giuseppe Nacci “La amenaza OMG (Organismos Modificados Genéticamente) en los modelos alimenticios deacompañamiento a la terapia inmunitaria y desintoxicante”………………………………………………….…….543ALLEGATED No. 19:SANA Kongress – 13. September 2008 in Bologna, Gefördert von AAM Terra Nuova, WissenschaftlicheKoordination: Studio Agernova, Dr. Giuseppe Nacci “Die GVO-Bedrohung (Genetisch Veränderte Organismen) fürbegleitende Ernährungsmodelle zur Immun- und Entgiftungstherapie“…………………………………..……..….566ALLEGATED No. 20Conferenza SANA (Bologna) 13 settembre 2008, AAM Terra Nuova, Coordinamento Scientifico : Studio Agernova,Dott. Giuseppe Nacci “La minaccia OGM (Organismi Geneticamente Modificati) sui modelli alimentari diaccompagnamento alla terapia immunitaria e detossificante”. …………………………….……………………..….590ALLEGATED No. 21: SICKO (Michael Moore) …………………………………………………………………..….591ALLEGATED No. 22 : Thirty Clinical Cases of Dr. Gonzales and Dr. Isaac (New York)………………………..…..596ALLEGATED No. 23 : Dott. Waisbren …………………………………………………………………………….….633ALLEGATED No. 24: Fifteen clinical cases of the Kroiss Center (Vienna, Austria)…………………………………63919

INTRODUCTIONFrom: “The Gerson therapy. The amazing juicing programme for cancer and other illnesses”, byCharlotte Gerson and Morton Walker, Thorsons ed.“During a three-day period, July 1 to 3, 1946, the United States Senate tooktestimony from nationally known cancer researchers relating to U.S. Senate Bill1875, also referred to as the “Pepper-Neely anticancer proposal”. In this bill,Senators Pepper and Neely recommended the appropriation of $ 100 million from theU.S. government’s budget for cancer researchers to find a cure for cancer once andfor all.After his two Washington, D.C.-based investigators, a physician and an attorney,reported back to Senator Claude Pepper (D-Florida) that Dr. Max Gerson did, indeed,have a successful treatment for cancer for the first time in history, the United StatesSenate invited a medical doctor to demonstrate his specific therapeutic approach forcuring cancer. Accordingly, Dr. Gerson brought five of his cured cancer patients andthe records of five more for presentation before the Pepper-Neely anticancersubcommittee of the Senate Committee on Foreign Relations of the Seventy-ninthCongress.The impressive testimony of this anticancer specialist and his patients caused SenatorPepper to call a press conference for bringing information about the Gerson Therapybefore the media. However, massive numbers of lobbyist for the immensely wealthyPharmaceutical Manufacturers’ Association (PMA), the American MedicalAssociation (AMA), and the American Cancer Society (ACS) prevailed on reportersto ignore the Gerson press conference and attend a cocktail party instead where freefood would be served and libations would be flowing. The only reporter whopreferred to hear the Gerson presentation was American Broad-casting Corporationnewscaster Raymond Gram Swing. During World War II, Mr. Swing had been afamous war correspondent on a par with Edward R. Murrow. He attended and tookcopious notes at the Senate press conference for use in his East Coast 600 P.M. ABCnetwork broadcast of Wednesday, July 3, 1946. Here is what Raymond Gram Swingbroadcast then throughout the United States:…“I hope I have my values right if, instead of talking tonight about the agreement reached on Trieste by the ForeignMinister in Paris, or the continuing crisis of the OPA in Washington , or President Truman’s signing of the Hobbsantiracketeering bill, I talk about a remarkable hearing before a Senate Subcommittee in Washington yesterday oncancer and the need for cancer research in new fields.A bill is before Congress, the Pepper-Neely bill, to appropriate a hundred million dollars for cancer research withsomething like the zeal and bigness with which it went for the release of atomic energy, turning the job over to thescientists with resources generous enough to solve the problem.20

This alone would make a good theme for a broadcast, just an example of the use a great democracy can make of itsintelligence and wealth. But the subject has been made peculiarly gripping by unprecedented happenings yesterdaybefore the subcommittee which is holding hearings on this bill, and of which Senator Pepper is chairman.He invited a witness, a refugee scientist, now a resident of New York, Dr. Max Gerson, and Dr. Gerson placed on thestand, in quick succession, five patients. They were chosen to represent the principal prevailing types of cancer, and ineach instance they showed that the Gerson treatment had had what is conservatively called “favourable effect on thecourse of the disease”. That in itself is remarkable, but it is the more so because Dr. Gerson’s treatment consists mainlyof a diet which he has evolved after a lifetime of research and experimentation. To say that Dr. Gerson has been curingcancer by a dietary treatment is medically impermissible, for the reason that there must be five years without recurrencebefore such a statement is allowed. Dr. Gerson has cured tuberculosis and other illnesses with his diet, but in the U.S.A.he has only been working on cancer for four and a half years…..Yet anything that offers even a possibility of treating successfully at least some of the four hundred thousand existingcancer cases in this country is stirring news, no matter how conservatively it is formulated. There would be non Pepper-Neely bill to appropriate a hundred million dollars for cancer research if the existing research were coping with theneed.…I have spoken about this carefully and abstractly, which underplays some of the shock and delight of the experienceyesterday at the hearing of the Pepper Committee. It is one thing to talk about chemistry and diet and vitamins and otherfactors in medical science. It is another to see, as the Committee yesterday saw, a seventeen-year-old girl, who had atumour at the base of the brain, which was inoperable, and which had paralyzed her. Yesterday, she walked withoutassistance to the witness chair, and told clearly about her case and her treatment.There was a sturdy man, who had been a sergeant in the army. He had had a malignant tumour, also at the base of thebrain, which had been operated on but needed deep X-ray treatment, and this he could not receive because of the dangerto the brain. Yesterday he was the picture of health as he testifield, and quite naturally he was proud of his remarkablerecovery.There was a woman who had had cancer of the breast which spread. Yesterday she was well, and testified with poiseand confidence.A few cases showing such improvement cannot, of themselves, affect the outlook of the medical profession. But theyare attested facts and not flukes, and as such they have to be accounted for. And there are many, many more caseswhich could have been cited.It would seem to be the business of medical research to leap on such facts and carry every hopeful indication to a finalconclusion….So the advocates for the Pepper-Neely bill can argue that, unless we learn now how to deal successfully with cancer,many millions of persons now living in this country are condemned to die from cancer. A hundred million dollars islittle more than a token payment for America to make, in order to avert such a sweep of death, and they can then pointto the Gerson dietary approach as a most promising field of research….Dr. Gerson was an eminent if controversial figure in pre-Hitler Germany. He was bound to be controversial because hewas challenging established practice in treating tuberculosis by diet. He has been assistant to Foerster, the greatneurologist of Breslau, and for years assistant to Sauerbruch, one of the great physicians on the Continent. TheSauerbruch-Gerson diet for skin tuberculosis is well-known to European medicine, and the account of it is part ofaccepted medical literature. Dr. Gerson told the Pepper Committee that he had first come upon his dietary theory intrying to cure himself of migraine headaches. Later he treated others, among them a man with skin tuberculosis as well.Dr. Gerson was an acknowledged dietary autority in Weimar Germany, and was responsible for the German army of histime being placed on dehydrated, rather than canned food…..Raymond Gram Swing continued with his network radio broadcast and brought insome additional news too. After he ended, the telephone switchboard lit up at theAmerican Broadeasting Corporation in New York City. People called in from all overthe nation to learn about the Gerson Therapy. But other, darker, more powerfulcommercial and political forces had been listening as well.The executive directors of pharmaceutical companies producing cytotoxic agents(Chemo-therapy) for cancer treatment – members of the PMA – threatened to cancel21

all radio advertising contracts for their drugs sold over the counter, an annual loss inrevenue for ABC amounting to tens of millions of dollars. Within two weeks of thatfateful radio broadcast which apprised people of a potential cure for cancer, afterthirty years at the same job Raymond Gram Swing was fired his position as anewscaster for the ABC network.You might also wish to know what happened to the Senate’s 227-page Pepper-Neelyanticancer bill of 1946-Document No. 89471. By efforts of the lobbyists workingwith four senators who were also medical doctors, the bill was defeated. Today,Document No. 89471 is stored in boxes and gathers dust in the archives of the U.S.Government Printing Office.Three questions you may understandably raise are:1) Why didn’t the U.S. Senate over half a century ago adopt the anticancer budgetarymeasure that came before it?2) Wasn’t the prevention of or treatment for Americans coming down with cancervital enough ?3) Why weren’t anticancer experts requested to at least test the Gerson Therapy backthen when senators were presented with the opportunity ?22

The case of the “LAETRILE” (Vitamin B17)Partially tract from “A Commonweal Working Paper”, by Vivekan Don Flint and Michael LernerResearch Assistance: Melanie Smith, October, 1997,The most enduring legacy of the meteoric rise of Laetrile to a place of preeminence among unconventional therapies forcancer during the 1970s may well be sociological and political, rather then medical in nature. Laetrile spawned apopular movement for freedom of choice in health care decisions spanning the ideological spectrum that probably hasnot been seen in this country since the time of Harry Hoxsey. Though it had been in use for at least 25 years as atherapy for cancer, it is estimated that at any given time during the mid-1970s, 70,000 people were using Laetrile as acancer treatment, for pain control or as a preventive measure.( 1421 )In the debate over broader philosophical and political issues, the critical question for cancer patients, whether or notLaetrile is an effective therapy for cancer, was largely overshadowed, though clearly Laetrile has not lived up to theexpectations of many of its most ardent advocates.According to journalist Michael Culbert, D.Sc., founding member of the Laetrile advocacy group Committee forFreedom of Choice in Cancer Therapy, Inc.:I decided very early that the issue was neither scientific nor medical but political. And that issue was--is--simple: Whatright does the state have, or should it have, to intervene in the medical decisions between a patient and his doctor,particularly if that patient is dying of a "terminal" disease for which there is no known, or guaranteed cure? ( 1422 )Ralph Moss, a key figure in the Laetrile controversy in the 1970s, has been a leading critic of the cancer orthodoxy, aswell as the political and economic forces he believes drive it, since leaving his position as Assistant Director of PublicAffairs at Memorial Sloan-Kettering Cancer Center (MSKCC) in 1977. Moss was fired for aligning himself publiclywith a group of MSKCC employees who believed the public was being given inaccurate information on the outcome ofanimal studies of Laetrile's effectiveness. Moss provides a detailed account of the Laetrile controversy and hisexperience at MSKCC in his book The Cancer Industry. Moss states the medical issue this way:”Laetrilists are not just advocating a single substance but, like the advocates of other unorthodox therapies, areproposing a new kind of treatment for the patient's body and mind”.There is apparently an irreconcilable difference between laetrilists and orthodox doctors in how they understand cancer.Since the time of John Hunter (1728-1793), orthodox physicians have tended to see cancer as a localized disease that,as Hunter said, "only produces local effects." Such a disease would therefore be curable through localized means--forexample, removing the growth through surgery....Experiments in this century, and particularly in the past thirty years, have suggested that the body has naturalimmune mechanisms against cancer analogous to those that function in microbial infections. The corollary of this viewis that cancer can be controlled by enhancing the body's normal immune functions, which orthodox methods tend todestroy. ( 1420 )The typical "metabolic therapy" often advocated by proponents of Laetrile includes megadoses of vitamins A and C,minerals such as selenium, and enzymes, particularly pancreatic enzymes. And, in order to free these enzymes to actupon cancer cells, practitioners often recommend limiting intake of animal protein. Alcohol, coffee, soft drinks andprocessed foods may also be proscribed.( 1423 )The early 1970s saw growing numbers of patients seeking out Laetrile as a cancer therapy and it was during this timethat the Laetrile became the focus of a large-scale political movement, as well. In June 1972, John Richardson, M.D., anAlbany, California physician whose used Laetrile in his rapidly-expanding practice, was arrested for violating state lawsintended to curtail its use. Richardson was a member of the conservative John Birch Society, and its membership ralliedaround the issue. The three trials of Richardson galvanized a national movement for freedom of choice in medicaltherapies, and the original Committee for Freedom of Choice in Medical Therapy, Inc. ballooned into a nationwidemovement in all 50 states with a membership estimated at 20,000 to 50,000 members. ( 1424 )In July 1973, Dean Burke, while still working with the NCI, wrote to Congressman Robert A. Roe that Laetrile hadbeen successful in NCI directed studies using the Lewis mouse lung cancer model while the agency consistently deniedits efficacy ( 1425 ).1975 was a pivotal year in the controversy over Laetrile. In that year a U.S. District Court judge barred the FDA from23

preventing patients from securing their own supplies of Laetrile from foreign sources. Later that same year, federalofficials conducted a crackdown on the importation of Laetrile into this country. Sixteen people, including RobertBradford, now affiliated with the American Biologics clinic in Tijuana, were arrested or indicted on charges ofsmuggling Laetrile from Mexico. The principles were eventually found guilty in a lengthy trial, though no prison timewas meted out ( 1426 ).The OTA also summarized the efforts by the NCI in the mid-1970s to obtain documented evidence of objectiveresponses to Laetrile using an approach designed to collect information from individuals or practitioners who felt theyhad used Laetrile successfully in the treatment of cancer. The intention was not to determine rates of success, but ratherto collect evidence of antitumor affect. The NCI sent nearly half a million letters to physicians, other healthprofessionals and to pro-Laetrile groups asking for documented case histories of patients who had shown objectiveresponses to Laetrile, with or without metabolic treatment, with a treatment period of at least 30 days, with a period ofat least 30 days prior where no conventional treatment had been used.Two hundred thirty patients responded with claims of objective response using Laetrile. Ninety-three of these gavepermission for release of their medical records, and for 26 of these insufficient information was provided for reviewpurposes. The final review was based on the remaining 67 cases. In an effort to avoid bias, twenty-six case histories ofpatients with similar cancers who received only conventional therapies were added to the Laetrile cases. Summaries ofthe course of the disease without information about the therapy used were prepared for each patient and presented to apanel of 12 oncologists from outside the NCI. A group consensus was reached for each case after a discussion of theindividuals reviews.The panel determined that there were two complete remissions, four partial remissions and nine cases of stable disease.Thirty-five cases were of no value since they did not meet the original criteria for inclusion, and 11 had insufficient dataupon which to judge responses. Despite the attempts to blind the panelists regarding Laetrile use, a higher than expectedproportion answered correctly when asked to guess which patients had used Laetrile. Interestingly, the consensus for thesix Laetrile-treated patients who were determined to have had partial or complete responses and for the threedetermined to have had increased disease-free survival, was that they had received conventional chemotherapy.In their discussion of the review, the authors point out that the relatively small number of case submissions and loss ofcases due to incomplete information left only a small number of evaluatable cases. Further:The patients treated with Laetrile were almost always given concomitant metabolic therapy...as well as generalsupportive-care measures such as improved diet, psychologic support and the unmeasurable ingredient of hope. Thisfact makes it difficult to attribute any tumor response to Laetrile alone ( 1427 ).http://www.mednat.org/cancro/ELLISON_1427.pdfFollowing this case review, the NCI sponsored phase I and II clinical trials, which were carried out at the Mayo Clinic.The phase I study gathered information about dosage and toxicity ( 1428 ) in preparation for the phase II study.One hundred seventy-eight patients with advanced cancers were treated with amygdalin according to a regimendesigned to resemble "current Laetrile practice," which included a special diet and vitamin supplements. A subgroup of14 patients with colorectal cancer was given a high-dose regimen of amygdalin and supplements resembling high-doseregimens used by some metabolic practitioners (http://fiocco59.altervista.org/nacci/Moertel%201982.pdf ) ( 1256 )All patients had disease for which no conventional therapy was available, though none were bedridden and all could eatnormally. About a third of the patients had had no chemotherapy whatsoever, significant because of the claims of manypractitioners that metabolic therapies are more effective in patients whose immune systems have not been damaged bychemotherapy.The amygdalin, prepared from apricot pits by the NCI, was administered intravenously for 21 days, followed bycontinuous oral administration which was terminated with progression of the disease or severe clinical deterioration.Three patients were taken off the regimen because of high blood levels of cyanide.One of the 175 evaluable patients demonstrated a partial response (at least a 50 percent decrease in the size of thelesion); this response was transient, however. By the end of the three-week course of intravenous amygdalin, more thanhalf of the patients demonstrated measurable disease progression. By seven months, all patients had progressive disease.Median survival for the entire group was 4.8 months, a result similar to that of the 14 high-dose patients. Theresearchers found little evidence of symptom relief. Toxicities were generally mild when patients adhered to treatmentschedules.24

The authors concluded that the survival times of the patients appeared to be consistent with survival times of patients"receiving inactive treatment or no treatment"( 1256 ). The OTA report notes that this comparison was not entirely valid,since the trial did not include a randomized control group and was not designed to determine if amygdalin causedmoderate increases in lifespan or improvements in well-being or pain control ( 1429 ).Laetrile supporters predictably criticized the study, claiming the material used was not Laetrile but a "degradedproduct."( 1430 ). The OTA Report counters that the Laetrile used was prepared according to one of several popularformulations in use at the time and that the regimen did correspond to current Laetrile practice ( 1431 ). AmericanBiologics, then a California company with ties to the Committee for Freedom of Choice in Cancer Therapy, had offeredto provide free Laetrile for the study and when the government refused the offer, the Committee unsuccessfully tried toblock the trial, believing the test substance was not pure amygdalin, but a form that would not release cyanide ( 1432 ).According to Culbert:The "Laetrile clinical trial"...wound up being in essence a US government sponsored test of an uncertain Laetrileproduct whose application was in the hands of doctors and scientists known to be or assumed to be hostile to Laetrile,whose patients were anonymous, and the test results of which, being coded, could not be individually released or crosschecked.Worse, the patients accepted for entry into the program were variously described as "terminal" or beyondhope of cure by conventional means, yet not at the "final stage."The government [released] data on the test before the trial results were published as a kind of slide presentation...ACommittee observer at the event was able to photograph a slide which showed that a significant number of test patientshad remained "stable" while on the injectable part of a program whose oral protocol, we had every reason to believe,was not strongly adhered to (and parts of which, as in suggested vitamin A levels) seemed not to have been followed atall. ( 1432 )The results of the trial published in the New England Journal of Medicine showed Laetrile to be ineffective as a cancertreatment, but Culbert and other Laetrile advocates believed the trial raised more questions than it answered:[D]epending on how the numbers were read, either a small majority or a large plurality of patients remained "stable"while on the injectable part of the program, and only advanced into further disease after the 21 days of injectionsceased. It later surfaced "anecdotally" that at least one patient was urged not to continue on the program (claiming hehad "done too well"). As a corollary, a preliminary test found amygdalin not to be toxic, at least in the ranges suggestedfor therapeutic use.( 1432 )And, according to Richard Walters, Dr. James Cason of the University of California, Berkeley, analyzed the compoundused in the Mayo Clinic study using infrared spectrophotometry and determined that it did not contain amygdalin at all( 1433 ).And in a charge often leveled at efforts to evaluate alternative therapies, opponents of the trial pointed out that 66percent of the patients had received chemotherapy which they believed had severely damaged their immune systemsand compromised their ability to respond to Laetrile.Though it continues to be used at several clinics in Mexico and by practitioners in the states where it is legal, in theminds of many, the Mayo Clinic trial was the final word on Laetrile. But for Laetrile advocates, the scientific questionslargely still unresolved, and there remains what seems to some to be abundant anecdotal evidence for the effectivenessof Laetrile. According to Culbert:There were too many doctors stepping forward with case histories...too many dissident scientists claiming there wassome merit in the notion of anti-cancer efficacy from glycosidic compounds, and far, far too many "anecdotes" frompatients treated in Mexico or even within the USA to be able to claim the apricot kernel extract was totally withoutvalue...[N]otable failures of Laetrile therapy got plenty of press attention, particularly if the failures came from the growingcaseloads of Drs. Contreras and Richardson. Such negatives were indeed reported in gruesome detail--yet it was onlyan occasional journalist who dared contrast failures on vincristine, 5 FU, adriamycin, radiation and surgery, sincesomehow a failure on an orthodox modality was somehow less a failure than one on unorthodox therapy ( 1434 ).In the political effort that had been spearheaded by the Committee for Freedom of Choice in Cancer Therapies, between1976 and 1981, bills decriminalizing Laetrile or legalizing it outright were approved in 24 states. Bills passed twice in25

New York, but were vetoed each time. Such laws remain in 20 states ( 1435 ). According to Culbert:The Committee stuck to a single sweeping principle--that the issue was not so much freedom for Laetrile as it wasfreedom of informed consent in cancer therapy in general, for physician and patient...One observer after another joinedthe conceptual battle and usually remained clear on the separation of the issues of freedom of choice in medicine vs. theefficacy of Laetrile: by what stroke of logic or presumed vested interest does the state have the right to intervene in lifeand-deathdecisions between a physician and a patient, particularly when the patient is said to be "terminal," as withcancer? ( 1436 )Today, it is illegal to use Laetrile in states that do not have laws specifically allowing it. In 1977, a U.S. District Courtjudge ruled that the FDA had acted illegally in seizing shipments of Laetrile, and he enjoined the FDA from furtherseizures; that injunction was overturned in 1979. In a separate decision, a judge set up a system under which a patientcould get Laetrile for personal use if a physician signed an affidavit that the individual was terminally ill, but his systemwas voided in 1987. As a result of these decisions, it is illegal to transport Laetrile across state lines or into the UnitedStates, even with a physician's prescription.Federal District Judge Luther Bohanon who established the affidavit system for Laetrile in 1977 offered his consideredview of the controversy:Advocates of Laetrile's use in cancer treatment include many highly educated and prominent doctors and scientistswhose familiarity and practical experience with the substance vastly exceeds that of their detractors. To deem suchadvocacy "quackery" distorts the serious issues posed by Laetrile's prominence and requires disregarding considerableexpertise mustered on the drug's behalf.While the record reveals an impressive consensus among the nation's large medical and cancer-fighting institutions asto Laetrile's ineffectualness, a disconcerting dearth of experience with the substance by such detractors is revealed...The current debate is fierce. The issue appears largely unresolved as to Laetrile's true effectiveness, in large partbecause FDA has prevented adequate testing on humans....It is only when the substance is openly used, and its results carefully observed and fully reported that this controversywill be resolved. ( 1437 )26

The Metabolic Therapy“Metabolic Therapy” indicates a whole range of medical therapies based on the idea that manydiseases are essentially caused by a deficiency in vitamins.The estimated number of vitamins is over 30,000 and only a small part was thoroughly studied.In some “alternative” private hospitals (SEE ATTACHMENTS N. 3 of this E-Book ) manychronic-degenerative diseases are treated with this therapy: cancer, leukaemias, AIDS, Type 2diabetes mellitus, Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, AmyotrophicLateral Sclerosis, autoimmune diseases, allergies, food intolerances, osteoporosis, etc.In the Metabolic Therapy high doses of vitamin are given not only orally but also intravenously,such as in the case of cancer (Laetrile, Elemene, vitamin C, etc…)Vitamin “Laetrile” intravenously:Morrone J.: Chemotherapy of inoperable Cancer. Preliminary report of 10 cases treated withLaetrile, Exp. Med. Surg., 20, pages: 299-308, 1962 (SEE chapter 7 of this E-Book ).Integral Text: http://www.mednat.org/cancro/morrone.pdfVitamin “Elemene” intravenously:Tan P.: Clinical study on treatment of 40 cases of malignant brain tumor by Elemene emulsioninjection Chin. J. Integ. Trad. Western Med, 20, pages: 645-648 (SEE Text in English and Chinese:http://www.mednat.org/cancro/cancro_cervello.pdfNeoplastons intravenously (for apoptosis of cancer), http://www.burzynskiclinic.com/ph/clinicaltrials.htmlAlso in Italy this kind of Medicine has recently established itself thanks to the great commitmentand genius of late doctor Valsè Pantellini, who introduced the use of vitamin C together withpotassium bicarbonate and obtained very good results in more than 5,000 clinical cases.Thanks to Father Romano Zago’s impassioned work, also the use of Aloe has recently obtainedremarkable results in Italy. The plant is quite rich in vitamins which stimulate the immune systemor induce the apoptosis.Other plants with the same mechanism of attack on tumours are those of the Canadian formulaESSIAC, which came in the limelight in Italy thanks to different authors.Nowadays the Metabolic Therapy includes a number of variants, each of them named after thedoctor who used it.Substantially, however, they can all be defined Gerson-like therapies, in remembrance of the greatdoctor Max Gerson (( 749, 750, 1360-1362, 1348, 1349, 1411 ), the first to understand the extreme importancefor Medicine to retrive the past classical values of correct nutrition, considered not only as apreventive measure against diseases, but also as real therapeutic method for the treatment of 20thcentury’s main chronic-degenerative diseases. After 2,500 years he thus revived concepts andthoughts that had already been developed by the great Greek doctor Hippocrates of Cos, the founderof Western Medicine.These metabolic therapies are very similar to one another and – according to the author of this paper– all based on the following 10 basic principles, at least as far as the treatment of malignant tumoursis concerned.27

First principleMalignant tumours (cancer, sarcomas, leukaemias, lymphomas) are caused by serious geneticmutations of the cell’s DNA (chromosome aberrations). For this reason, the first cause ofmalignant tumours can be identified as chronic deficiencies in vitamins (their lack does not enablethe body to repair the genetic damage or to induce apoptosis in affected cells), so that the treatmentof these tumours must be based on the intake of high doses of vitamins to produce the spontaneoussuicide (apoptosis) of tumour cells. Some of these vitamins can also be taken intravenously toincrease their accumulation on tumours. The percentage of their accumulation on tumours canindeed be assessed on the basis of pharmacokinetic predictive calculations in line with the “tracertheory” of nuclear medicine and/or functional magnetic resonance imaging ( 1753 )Note 1: Chromosome aberrations allow correct diagnosis of certain types of lymphomas and leukaemias, clearly andunivocally differentiating them from infective diseases which are quite similar to them, such as infectiousmononucleosis (see chapter 17 of this E-Book)Note 2: It is absolutely contraindicated to administer CHEMO-THERAPY to patients suffering from cancer,leukaemias, sarcomas or lymphomas, as it destroys immune defences of the body and organs themselves. Under nocircumstances should this therapy be used because it does not make sense to poison the body of a patient who is alreadyseriously ill. Besides, the Hippocratic oath itself forbids to give poison to patients.Second principle:The keystone for the “metabolic” treatment of cancer and other malignant tumours is based first ofall on the following principle: depriving the tumour of whatever feeds it . The treatment mustsubstantially be based on removing proteins from an onocological patient’s diet, i.e. removing atleast one of the essential amino acids (Leucine, Valine, Isoleucine, Lysine, Methionine, Tryptophan,Threonine, Phenylanine, Histidine) that are needed to synthesize new proteins (and consequently,new cells), because the intake of proteins would also enable tumour cell replication. For example, apaper published in 2006 showed once again that removing even one essential amino acid only isenough to block cell replication ( 1738 ). In this work, a decision was taken to measure the level of“total proteins” in the bloodstream. If a hypoproteic diet is implemented correctly, these levelsshould be very low compared to normal, accettable ranges – ideally between 6.0 and 6.6 grams/100millilitres of blood. It would then be up to the doctor in charge of the case to decide whether theselevels should be pushed below the 6.0 limit. Since most foods containing all 9 essential amino acids(meat, eggs, yeast, sprouts, milk and milk derivatives) also contain vitamin B 12 (which is alsonecessary for cell proliferation), it was also deemed useful to measure its levels as an indirectindicator of the patient’s compliance with the hypoproteic diet. With respect to the prescribeddietary treatment, patients were considered to be compliant if they managed to keep very lowvitamin B 12 levels, i.e. below 150-200 picograms/millilitre of blood. Out of about 40 clinical casesobserved by the autor since 2002, no patient has shown values below 100 picograms/millilitre ofblood, most probably because the liver itself is a major supplier of vitamin B 12 if this is not part ofthe diet – even over periods of more than 4-5 years (as shown in medical-scientific literature).Third principleThe keystone for the “metabolic” treatment of cancer and other malignant tumours is based on asecond principle as well: giving the tumour what kills it (but without damaging the patient).This principle is primarily based on the use of great amounts of natural vitamins with a view totaking advantage of their ability to induce the apoptosis of tumours cells and, secondarily, on thefact that natural vitamins also induce a block in tumour cell replication; furthermore, they also leadto the anti-angiogenesis of neoplastic capillaries, they prevent cancer cells from producing PIF(Proteolisis Inducing Factor) and they stop the growth of tumour cells.28

Note : in order to exploit their ability to induce the apoptosis of tumour cells, SEE chapter 6 of this E-Book orhttp://www.mednat.org/cancro/TERZO%20CONGRESSO%20_Roccamorice.pdf )Fourth principleImmune response against the tumour. All these therapies use phyto-therapeutic systems (Aloe,ESSIAC, Graviola, Mistletoe) or other systems (e.g., lipopolysaccharides) to trigger leukocytesagainst tumour cells (SEE chapter 9 of this E-Book).Metabolic therapies consider fever as a form of patients’ natural hyperthermia, which – similarly tothe well-known hospital radiotherapy HYPERTHERMIA induced by hospital equipment – causesthe spontaneous necrosis of tumour cells, as neoplastic masses are poorly vascularized and thereforeparticularly vulnerable to the hyperthermic effects of the fever itself. The blood values that areroutinely checked in patients are, consequently, the total amount of Leukocytes, the percentage ofLymphocytes (which must exceed at least 35-40%) and the Erytrocyte Sedimentation Rate (ESR),which must exceed at least 12 millimetres/first hour.The immune response is guided by Lymphocytes T gamma delta, cytotoxic Lymphocytes T, Killerand Natural Killer Lymphocytes: these are outright guiding systems for a complete immuneresponse of the patient against the tumour (starting the immune cascade). A number of scientificpapers have been published on the subject ( 32, 61, 132, 198, 319, 373, 406, 418 ) ; in particular, on brain cancers( 180, 351, 368 ); on breast cancers ( 11,82 ); on colon cancer ( 394 ); on leukaemia ( 67 ) ; on liver cancers ( 374 );on kindney cancers ( 350 ); on lung cancers ( 419,500 ) ; on malignant melanoma ( 9,126 ). However, it hasbeen shown that negative stress tends to curtail the immune response ( 591-594, 1696 ).Fifth principleLiver detoxification through vitamins with hepatoprotective activity and enemas of Coffeaarabica and/or Matricaria camomilla. Vitamins must be able to provide for the elimination oftoxic substances, which are purified by the liver through the bile (choleretic and cholagogicactivity), without toxins being re-absorbed by the intestine (laxative vitamins). Their use isextremely important as it allows for the rapid elimination of the toxins released by tumour masses(which are inflamed and therefore larger as a result of the immune response), thus reducing the painderiving from the tumour masses themselves. The liver plays a major role in the above-mentionedmetabolic therapy. Liver transaminases SGOT and SGPT, Gamma GT and Total bilirubin wereadopted as indirect indicators of the liver’s depurative activities. The enemas of Coffea arabicaand/or Matricaria camomilla are important for the Gerson metod and must be carried out every day.Of equal importance are the hepatoprotective vitamins contained in Silybum marianum, Taraxacumofficinale, Smilax aspera, Cynara scolymus, Salvia officinalis, Agropyrum repens, Hyssopusofficinalis and Matricaria camomilla, intake of which must never be discontinued.Sixth principleThe metabolic therapy counters intestine DYS-BIOSIS. This therapy helps prevent the risk ofdisrupting the normal intestinal bacterial flora (saprophyte bacterial flora), which is responsible forthe fundamental assimilation of the natural vitamins contained in vegetable foods (fruit, vegetables,cereals, legumes). As a result, it is also based on the use of intestinal milk enzymes, with a view tore-establishing the SYM-BIOSIS between human body and saprophyte germs and obtaining a goodnutritional balance with vitamin assimilation.Seventh principleMaintaining Glycemia at low levels and avoiding glycemic peaks. Glucose is needed by tumourcells to obtain energy and replicate their DNA. In metabolic therapies, very complex dietaryprotocols are studied, although they all share similar approaches: frequent but small meals withhypoglycemic foods. Some doctors, above all outside Italy, also give insulin to their patients, even29

when the latter do not suffer from diabetes. In the study at hand no insulin was given, but the bloodvalues of Glucose or Glycated haemoglobin were frequently analysed.Eighth principleUse of proteolytic enzymes. The use of proteolytic enzymes has been deemed beneficial by severalauthors. It is aimed to inducing greater absorption of natural vitamins at the gastroenteric level andgreater immune responses against the patients’ tumour masses, as shown primarily by the GersonFoundation ( 749, 750, 1348, 1349, 1360-1362, 1411 ).Ninth principleUse of specific unsaturated fatty acids instead of saturated ones. Unsaturated fatty acids(Omega-3 in particular) appear to improve the functionality of cell walls, thus allowing naturalvitamins to easily penetrate diseased cells and induce apoptosis and other related actions, includinggreater absorption of glucose in patients’ cells and subsequent lower glycemic values in thebloodstream. Their effects are, however, much broader and multi-faceted, as evidenced by Pardini( 1647 ) and Noguchi ( 1654 ).The alpha-linolenic acid (vitamin F), for instance, is a cis-polyunsaturated fatty acid that iscontained in linseed cold-pressed oil: it is transformed into EPA and DHA (Omega-3 fatty acids)and is quite effective against malignant tumours, as shown by Pardini ( 1647 ); moreover, Noguchi hasproved that Omega-3 fatty acids, unlike Omega-6 fatty acids, help reduce tumour masses, althoughOmega-6 fatty acids are unsaturated fatty acids, too ( 1654 ).Tenth principleSodium/Potassium balance. The use of Potassium and Magnesium plays a vital role. In particular,the use of Potassium has already been discussed by several authors ( 1348, 1349, 1411 ) who followedGerson’s studies. The behaviour of human cells resembles more that of granules in a Potassium-Sodium Exchange than that of simple water pockets. In this context, Magnesium, Germanium ( 269 ),Selenium, Iodine and Silicium are fundamental minerals, too. Conversely, the smallest possibleamount of Sodium must be taken ( 749, 750, 1348, 1349, 1360-1362, 1411 ).NOTE: the Metabolic Therapy is NOT Complementary or Alternative Medicine but simplyEvidence Based Medicine. In particular, it is NON-Pharmaceutical Medicine, as it is free from thecommercial interests of chemo-pharmaceutical Drug Multinationals.Case historiesVery interesting is the comparison between the “METABOLIC THERAPY” and modernantitumour therapies, which are all based on Chemotherapy, Radiotherapy and Surgery.As far as Gerson or Gerson-like therapies are concerned, a few useful LINKS are listed here below.Today the Gerson therapy is recognized by the American government. It is perhaps the most knowntherapy, above all in America (http://www.gerson.org). Famous is the scientific study conducted in1995 on 153 patients suffering from malignant melanoma, which demonstrated percentages ofremission much higher than those obtained with conventional therapies (40% of surviving patientsas against 6% with Chemotherapy). www.gerson-research.org/docs/HildenbrandGLG-1996-1/index.html30

Here are some data regarding other doctors who adopted Gerson-like techniques.Binzel E.P.: “Alive and Well”. In 1994, professor Binzel published the results obtained by treatinghis patients between 1974 and 1991. Out of 180 patients suffering from primary cancer (notmetastasized and circumscribed to one single organ or tissue), 131 were still alive in 1991, when thereport was published. In that year, 58 patients had been followed for 2-4 years, whereas 80 for 5-18years. Out of the 42 patients who died in 1991, 23 died of cancer, 12 of “unrelated causes” and 7 of“unknown causes”. Among patients with metastasization, 32 out of 108 died of cancer, 6 of“unrelated causes” and 9 of “unknown causes”. Out of the 61 patients who were still alive in 1991,30 had been followed for 2-4 years, 31 for 5-18 years.http://www.mednat.org/cancro/ALIVE_AND_WELL.pdfAlso the late German doctor Hans Nieper gathered data about approximately 1,000 cases(http://www.mwt.net/~drbrewer).Doctor Catherine Kousmine is also well renowned.She studied many other diseases, above all Multiple Sclerosis, and documented more than 600cases. Kousmine, Catherine: http://www.kousmine.com/serv02.htm;http://www.kousmine.com/services.htmThe great Russian doctor TH. Inosmettzeff worked at the Tsar’s court and in 1844 documented hisfirst two cases of patients with cancer who were cured by using Laetrile (vitamin B17). His work isavailable in German at: http://www.mednat.org/cancro/inosmetzeff.pdfOn the Laetrile, SEE also Rossi and Guidetti (1966) with150 clinical cases :http://fiocco59.altervista.org/vitamina_b_17.htmOther doctors who applied Gerson-like therapies:Alvarez , MD http://stellamarisclinic.com http://www.nfam.org/treatment/clinicstella.htmlAndrade, Gustavo MD. http://www.bajaonline.com/dr-andrade/programs.htmBeals, Paul M.D.Brodie, Douglas MD http://www.drbrodie.com/cancermanagement.htmBormann, Carolyn , MD Europa Institute of Integrated Medicine ;http://www.arrowheadhealthworks.com/cancer.htm.Bradford, Robert, MD http://www.americanbiologics.comBurzynski, Stanislaw R. M.D. www.cancermed.comCallebout, Etienne, M.D. London, EnglandCastillo Ramos , MD http://www.drcastillo.com/Dorman, MD http://www.paracelsusclinic.com/Edelson, Stephen M.D. http://www.edelsoncenter.com/Forror, Kenneth M.D. http://www.lfmc.net/Forsythe, James M.D. http://thecrew2.reno.powernet.net/virtual/drforsythe.com/index.php.Gonzales, Nicholas James (http://www.dr-gonzalez.com/maver_article.htm ; http://www.drgonzalez.com/)Guidetti Ettore , MD. http://fiocco59.altervista.org/vitamina_b_17.htmHoffer Abram, M.D. CANADA, http://www.islandnet.com/~hofferHopper Douglas http://www.yourowndoctor.com/aboutus.asp?site=2092&doc=2092,Howard Straus, M.D. http://www.gerson.org31

Inosmetzeff http://www.mednat.org/cancro/inosmetzeff.pdf ;http://www.mednat.org/cancro/inosmetzeff2.pdfIssels Joseph. MD, Germany (Keller, Helmut Stella Maris Clinic in Mexico.Kroiss, Thomas, M.D. in Vienna, Austria http://www.kroisscancercenter.com/Manner Harold, MD, Harold Manner CenterNagourney, Robert M.D. http://www.rationaltherapeutics.com/Pauling Linus http://www.paulingtherapy.com/Pesic, Milan M.D. (Germany)Privitera, James M.D http://www.nutriscreen.com/Revici, Emanuel M.D., Revici Life Science Center,Richardson, John “Laetrile case Histories; the Richardson Cancer Clinic Experience”(http://www.realityzone.com/lcm.html )Rizov, Vladimir M.D., www.newvitality.comRodriguez, Rodrigo M.D. http://www.ibchospital.com/Rossi Domenico M.D., http://fiocco59.altervista.org/vitamina_b_17.htmRoundtree, Robert M.D., Robert C. Roundtree, M.D.,Rowen, Robert M.D. http://www.doctorrowen.comRubio, Geronimo MD http://www.ami-health.com/http://www.cancure.org/american_metabolic.htm.Schachter, Michael B. M.D. http://www.mbschachter.comStoff, Jesse M.D., Immune Therapies International (ITI).Tasca, Marco M.D., http://www.mednat.org/cancro/tasca.pdf )Taylor, Lawrence, MD Lawrence H. Taylor, M.D.,Waisbren, Burton, M.D. www.waisbrenclinic.comWatayo, Takaho, M.D. TokyoYoshihiko, Hoshino, M.D. TokyoAlthough this high-dose vitamin therapy is based on specific scientific and medical knowledge, ithas been relegated to the field of “alternative” therapies owing to the commercial interests ofchemo-pharmaceutical lobbying groups: the question raised by the use of Laetrile for cancertreatment in the ’70s in the USA is an example of that (SEE chapter 7 of this E-Book).The European Commission (Internal Market, Tourism and Consumer Protection sections of theEuropean Union) has recently presented a proposal of a directive concerning vitamin integrators,natural and nutritional products in the European Union (SEE chapter 1 of this E-Book).The European Commission essentially wants to:1) limit strictly maximum doses of vitamin and mineral allowed in integrators (article 5 of theproposal for directive);2) eliminate from the market all sources of vitamins and minerals which are not contained in arestricted list of “allowed chemical substances”;3) eliminate herbal products from free marketization in Europe, with the obligation to be registeredas “herbal traditional medical products” (proposal of the Commission for a directive concerningherbal traditional medicines – 3th draft, May 2001);4) prohibit information about preventive and curative properties of vitamins and herbs, by declaringthis information illegal if connected in any way with a product.32

For information about these 4 points, see:http://www.alliance-natural-health.org;http://curezone.com/forums/m.asp;http://curezone.com/forums/m.asp?f=237;http://curezone.com/forums/m.asp?f=237&i=597;http://www.healthchoice.org.uk,http://www.healthchoice.org.ukAuthor’s proposals concerning the MetabolicTherapyThe Civil Society should understand that if the METABOLIC THERAPY – here shortlysummarized – were really accepted and promoted, it would bring considerable advantages in thehealth service.A programme consisting of 4 points is here proposed:1) Acceptation of the above-mentioned 12 principles, considering, however, some necessary“flexible” uses of specific methods applied by single doctors or groups of doctors, which – in anycase – are based on right diet and foster a real Italian Organic Farming, in order to make thistherapy little expensive and affordable for every Italian family.2) Request to the European Government to prohibit every kind of GMO food cultivation orimportation, which causes the failure of Metabolic Therapies in the treatment of chronicdegenerativediseases such as malignant tumours (Cancer, Leukemias, etc…), benign tumours andother diseases affecting a vast share of the Italian population (Adult diabetes, Alzheimer’s disease,Multiple Sclerosis, cardiovascular diseases, hypertension, autoimmune diseases, etc…)3) Request to the European Government to control and defend the national territory against thecriminal abuse of illegal and toxic dumps which – by poisoning soil and water – will hinder us from1) feeding population with clean organic food and water 2) curing chronic-degenerative diseases(see principle no. 3).4) Public or private Histological Diagnosis Centres should be able to regularly research and identifyGMO transgenic Retroviruses (or at least some of them, such as the S35 CaMV Promoter -Cauliflower Mosaic Virus - in human neoplasias which were surgically removed from patients onlyrecently, as GMOs pose a serious threat to our health (SEE chapter 8 of this E-Book).In this way they could possibly prove that GMO Multinationals are directly responsible for theonset of human tumours among the Italian population. Note: these transgenic retroviruses must bedifferentiable from “natural” ones (SEE chapter 2.22 of this E-Book)Therefore it is necessary to have the exact genetic code of all GMO retroviral promoters which areobtained in the laboratory and then patented in order to allow for GMO food marketing.Consequently, a legal assessment against any kind of industrial secrecy concerning GMOs isneeded. The term “commercially confidential” used on some documents is a way of not lettingpeople know about them. This goes against the recommendations of the Aarhus Convention, whichis an agreement of the United Nations Economic Commission for Europe linking the environmentto human rights.33

Chapter 1 : FoodThe food which we eat should be understood in its biochemical components. From thesecomponents we achieve our ability to defend our health, and therefore, to live as long as possiblewithout disease, in good psycho-physical condition. In this sense, chronic-degenerative diseasessuch as arthrosis, osteoporosis, autoimmune diseases, tumours, heart diseases, diabetes, andneurological deficits (Alzheimer’s, Parkinsonisms, Multiple Sclerosis, etc…) would be controlledmore effectively.Food is divided as:1) Carbohydrates2) Proteins3) Fats and/or Oils4) Vitamins34

Chapter 1.a: CARBOHYDRATESCarbohydrates are important because they give us CALORIES, the energy we need to live. Pasta,rice, bread, potatoes, and beans, are broken down into simple sugars (GLUCOSE), which will belater used by our cells to be chemically “burned” to obtain the chemical energy that is necessary forcell functionality. The daily requirement for an adult weighing 70 kilograms is about 2,000-2,500Kilocalories.Note: for athletes, energy requirements can reach about 4,000-4,500 Kilocalories per day. In severesituations, such as for severe burns, they are significantly higher: about 6,000 Kilocalories per day.There are ready-made commercial sugars as well (white sugar, brown sugar, chocolate, glucose,mannose, ribose, galactose, etc.), or natural food that is especially caloric, such as bananas, honey,kakis, plums, pumpkins.Very few people know that fruit itself (not vegetables) can give as many Kilocalories as a dish ofpasta, rice, bread, potatoes, or even of milk, dairy products, meat, eggs, fish, etc, that is to say, foodthat is actually high in PROTEIN content.Indeed, fruit can give the following Kilocalories:1 litre of well-whisked fresh fruit(^) (grapes and/or berries) gives about 800-900 Kilocalories, thatequals:750 cc milk (*),or: 70 grams cheese (*),or: 650 grams meat (*),or: 800-900 grams fish (*),or: 10 eggs (*)….There are also other types of fresh fruit that are rich in energy, although in smaller amounts:1 litre organic apple juice corresponds to 500 Kilocalories1 litre organic cherry juice corresponds to 450 Kilocalories1 litre organic pear juice corresponds to 420 Kilocalories1 litre organic orange juice corresponds to 400 Kilocalories(^) FRUIT is usually known as a great source of VITAMINS (SEE below).(*) MEAT, FISH, EGGS, MILK and dairy products (CHEESE, BUTTER, YOGHURT,MOZZARELLA CHEESE) are known especially as sources of PROTEINS (SEE below), ratherthan sources of energy (Kilocalories)Table 1 shows various types of food according to the amount of Kilocalories they give (from themost caloric to the least caloric).We need to know that ALL types of foods are important for their CALORIES, however forPROTEINS, FATS (or OILS), and VITAMINS as well.Note: women especially are obsessed by consuming “too many” CALORIES that make them gainweight… However, CARBOHYDRATES are not responsible for weight gain, as we will see later.PROTEINS are the true cause for extra weight.35

Table 1: Kilocalories per 100 grams of foodFoodKilocalories per 100 grams of foodMixed Seed Oil 900Olive Oil (Olea europaea) 900Sesame Oil (Sesamum indicum) 900Grape Seed Oil (Vitis vinifera) 900Lemon Oil (Citrus limonum) 900Corn Oil (Zea mays) 900Sunflower Oil (Helianthus annuus) 900Bananas (Musa sapientum) 660Dried Walnuts (Juglans regia) 660Dried Nuts (Corylus avellana) 625Roasted peanuts (Arachis hypogaea) 597Dried Pumpkin Seeds (Cucurbita maxima) 585Walnuts (Juglans regia) 582Raw peanuts (Arachis hypogaea) 571Crisps (inadvisable) 568Pine nuts 567Sweet almonds (Prunus amygdalus) 542Roasted/Fried Pork Fat (still under assessment) 523Pasta with Citron (Cedrus medica) 486Bread-sticks (sugar free) 433White Wheat (Triticum sativum) 416Rusks (sugar free) 410Dry biscuits (sugar free) 409White Pizza 408Wholemeal Crackers (sugar free) 403Dried Lupins without pod (Lupinus albus) 402Oat flakes (inadvisable) 395Finger Biscuits (sugar free) 392Oat Flour 388Grated bread (without yeast) 387Sweet Chestnut Flour (Castanea vesca o sativa) 371Japanese Rice Flour (Oryza sativa) 370Wholemeal Rusks (sugar free) 369Focaccia 369Pastries with Egg Cream 368Rice Cream (raw) (Oryza sativa) 366Wholemeal Corn Wheat (non GM) 365Cornflakes (inadvisable) 364Gluten Pasta 363Rice (Oryza sativa) 363Rice Flour (Oryza sativa) 363Tapioca, Cassava (Manihot utilissima) 363Pearl-Barley (Hordeum vulgare) 363Double-cooked Bread (without yeast) 361Barley Wheat (Hordeum vulgare) 360Gluten Semolina Pasta 358Dried Stockfish 358Pasta 356Wholemeal Corn (Zea Mays) 355Wholemeal Pasta 350“Genovese” Focaccia 350Potato Flour 349Dried Sweet Chestnuts (Castanea vesca o sativa) 349Coconut (Cocos lucifera) 346Peeled Dried Broad Beans (Vicia faba) 343Hard Flour 343Soft Flour 34336

Cracotte Biscuit 336Dried Chickpea (Cicer arietinum) 334Wholemeal Japanese Rice (Oryza sativa) 334White Pizza (bought in a pizzeria) 329Japanese Rice Cream (cooked) (Oryza sativa) 329Dried Lentils (Ervum lens) 325Whole Wheat Flour (Triticum) 321White Pizza (bought at a baker’s) 319Soft wheat (Triticum vulgare) 319Hard Wheat (Triticum durum) 314Semolina 314Dates (Phoenix dactylifera) 313Dried Beans (Phaseolus vulgaris) 311Puff Pastry 309Dried Peas (Pisum sativum) 306Dehydrated Mushroom Soup (inadvisable) 304Honey 303Oil Bread Rolls 302Dehydrated Asparagus Soup 301Tortellini Pasta 301Dehydrated Vegetable Soup 298Bread (without yeast) with Potatoes 296Prepacked Almond Toffee 295Soft Wheat Bread (50 grams) 290Dried Figs (Ficus carica) 288Raisins (Vitis vinifera) 283Dehydrated Pea Soup (Pisum sativum) 281Oven-roasted Figs with Almonds 277Hard Wheat Bread (100 grams) 276Hard Wheat Bread (50 grams) 267Pastry with Egg Cream and Liqueur 266Pickled Eel 259Tuna (drained from oil) 258Pizza with Tomato Sauce 247Whole Meal Bread (without yeast) 243Rye Bread (without Yeast) 241Sea Eel 237Black Olives (Olea europea) 234Salted Herring 218Anchovies in Oil 206Wheat Bran 206Pickled Herring 199Precooked Frozen Fish Sticks 191Chestnuts (Castanea vesca o sativa) 189Pickled Mackerel 177Mackerel 168Apricots in Syrup (Prunus armeniaca) 155Dried Plums (Prunus spinosa) 152Green Olives (Olea europea) 142Carp 140Frozen Precooked Cod 139Orange Ice-lolly 137Lamb Thymus 131Sardine 129Grey Mullet 127Mullet 123Dried Salted Cod 122Pears or Cherries in Syrup 116Lupins (bitter taste removed) (Lupinus albus) 11437

Beans (Phaseolus vulgaris) 104Dried Salted Cod Fillets 104Frozen Precooked Rice with Seafood 103Pickled Tuna (drained) 103Dentex 100Tomato Sauce (Solanum lycopersicum) 96Anchovies 96Soaked Dried Salted Cod 95Soaked Stockfish 92Sweet Potatoes 91Frozen Gilthead 90Frozen Grouper 86Lobster 86Trout 86Sole 86Potatoes (Solanum tuberosum) 85Peaches in Syrup (Prunus persica) 85Sweetcorn (Zea mays) 83Bass 82Rhombus 81Frozen Sole 81Smooth Dogfish 80Luce 80Apple Jam Tart (Malus communis) 79Mussels 77Tench 76Peas (Pisum sativum) 76Frozen Cod 75Atlantic Cod 72Clam 72Cuttle-fish 72Mandarin (Citrus deliciosa) 72Cod 72Shrimps 71Oyster 69Skate 68Squid 68Snails 67New Potatoes 67Black Grapes Juice (Vitis vinifera ) 66Kaki (Diospyros kaki) 65Frog 64Black Grapes (Vitis vinifera) 61Natural Apricot Juice (Prunus armeniaca) 59Octopus 57Natural Fruit Juice 56Clementines 53Indian Fig Opuntia (Opuntia ficus indica) 53Kiwi (Actinidia chinensis) 52Frozen Precooked Pasta with Beans 51Natural Peach Juice (Prunus persica) 50Figs (Ficus carica) 47Apples (Malus communis) 45Plums (Prunus spinosa) 42Pears (Pyrus communis) 41Sour Cherries 41Garlic (Allium sativum) 41Cherries (Prunus avium) 38Spring Onions 3838

Brussel Sprout (Brassica oleracea bullata aut gemmifera) 37Broad Bean (Vicia faba) 37Wild asparagus35(Asparagus officinalis, adscendens, racemosus).Raspberries (Rubus idaeus) 34Oranges (Citrus aurantium) 34Quinces (Cydonia oblonga) 34Melon (Cucumis melo) 33Natural Orange Juice (Citrus aurantium) 33Carrots (Daucus carota) 33Black Truffle 31Sweet Soda 31Spinachs (Spinacia oleracea) 30Field Asparagus29(Asparagus officinalis, adscendens, racemosus).Leek (Allium porrum) 29Apricots (Prunus armeniaca) 28Medlar Fruits 28Peaches (Prunus persica) 27Strawberries (Fragaria vesca) 27Broccoli (Brassica oleracea botrytis aut italica) 27Grapefruit (Citrus decumano, paradisi) 26Onions (Allium cepa) 26Cauliflower (Brassica oleracea botrytis) 25Green Cabbage 24Hothouse Asparagus24(Asparagus officinalis, adscendens, racemosus)Knob Celery (Apium graveolens rapaceum) 23Artichokes (Cynara scolymus) 22Winter Melon (Cucumis melo) 22Sweet Peppers 22Turnip Broccoli 22Turnip Leaves (Brassica rapa) 22Peeled Tomatoes (in a tin) + liquid 21Celery (Apium graveolens dulce) 20Parsley (Apium petroselinum) 20Red Cabbage 20Beetroot (Beta vulgaris cruenta) 20Cabbage Letture 19Green Head Cabbage19(Brassica oleracea capitata)Lettuce (Lactuca sativa) 19Ripe Tomatoes 19Yellow Pumpkin 18Turnip (Brassica rapa) 18Green Beans 17Common Chicory (Cichorium intybus) 17Garden Cress (Lepidium sativum) 17Chard (Beta vulgaris cycla) 17Tomatoes for Salad 17Endive (Chicorium endivia latifolium) 16Aubergines (Solanum melongena) 15Watermelon (Citrullus vulgaris) 15Cutting Lettuce 14Cucumbers (Cucumis sativus) 14Green Root Chicory (Cichorium intybus) 14Red Root Chicory (Cichorium intybus) 13Cutting Chicory (Cichorium intybus) 12Pumpkin Flowers 1239

Zucchini (Cucurbita pepo) 11Mushrooms (INADVISABLE) 11Lemon (Citrus limonum) 11Radish (Raphanus sativus parvus) 11Chicory (Cichorium intybus) 10Thistles (Cynara cardunculus) 10Fennel (Foeniculum vulgare dulce) 9Lemon Juice (Citrus limonum) 640

Chapter.1.b: PROTEINSPROTEINS are made of approximately 20 amino acids. Nine amino acids out of these 20 are calledESSENTIAL AMINO ACIDS; since our body is not capable of synthesizing them it needs toassimilate them from food. These ESSENTIAL AMINO ACIDS are Valine, Isoleucine, Leucine,Lysine, Methionine, Histidine, Tryptophan, Phenylalanine, and Threonine (Arginine inchildren).Without the external supply of these NINE ESSENTIAL AMINO ACIDS from food, the body isnot capable of building these PROTEINS.The 9 ESSENTIAL AMINO ACIDS must be present in cells all together at the same time tointeract with the biological systems controlling the production of the various required PROTEINS,in the time span of about one hour.If one of the essential amino acids is not present, cells will not be able to build the requiredPROTEINS. Therefore, the remaining 8 ESSENTIAL AMINO ACIDS will be used as a source ofenergy (Kilocalories).With PROTEINS, every cell in the human body is replaced by a new one, in a period of elevenmonths. Indeed, PROTEINS are used to build new cells and tissues, and to repair body organs.We can find the 9 essential amino acids in MEAT, FISH, EGGS, MILK and dairy products(CHEESE, BUTTER, YOGHURT, MOZZARELLA CHEESE).Fruit and Vegetables contain few of the essential amino acids.Cereals and legumes contain up to 7-8 essential amino acids, but the complete range of 9 essentialamino acids is never contained in any of them.Usually, cereals do not contain Lysine, and legumes do not contain Methionine.However, if we eat LEGUMES and CEREALS in a time span of about one hour, we will give ourbody all 9 essential amino acids. Besides, cooking traditions all over the world have alwaysassociated cereals to legumes as a sort of “meat for the poor”.In the Eastern countries rice, a CEREAL, was consumed with soybean, a LEGUME.In the Western countries wheat, a CEREAL, was consumed with bean or peas, that is LEGUMES.Cereals: WHEAT (soft or hard), RICE, SWEETCORN, SPELT, BARLEY, MILLET, OAT, RYE,SORB, KAMUT, QUINOA, AMARANTH.Legumes: BROAD BEANS, PEAS, BEANS, CHICKPEAS, SOYBEANS, LENTILS, CLOVER,FENUGREEK, GOAT’S RUE, LUCERNE, CAROB.Thus, PROTEINS are of vital importance for sustenance.Without PROTEINS, children cannot grow up and develop properly. That’s why, in mammals,evolution invented MILK, a sort of “LIQUID MEAT”: a newborn calf can become a steer in veryfew months, just by drinking milk from the cow…41

However reptiles, amphibians, birds and fish invented EGGS as a source of PROTEINS, that areessential for their young to develop as embryos as well. EGGS are a supply of PROTEINS ready foruse.Many people still believe that PROTEINS have to be eaten every day in great quantity (at least 60grams per day).This is not true: many patients manage to heal from very severe forms of chronic-degenerativediseases just by completely suspending the supply of all 9 essential amino acids for many months,obviously under the supervision of a doctor, in order not to have severe forms of proteinmalnutrition due to lack of food (see for example blood tests searching for “Total Proteins”,“Albuminemia”, “Pre-albuminemia”, etc...).Indeed, apart from forms of life such as fish, reptiles and birds, that still use EGGS, it has beenshown that PROTEINS (MILK) are only constantly needed in young mammals. This explains whyall mammals suckle their offspring until weaning, after which they stop feeding them with milk.No MAMMALS feed on MILK after weaning, apart from humans. It is strange that humans stilluse cow’s, goat’s or other mammals’ MILK even at an adult stage, when they do not need it anymore.At the moment, many doctors, including the writer of this book, believe that MILK and dairyproducts are a source of diseases if eaten by adults, or at least they cause damage to thebiochemistry of our cells.This is because MILK is a rich source of PROTEINS.Similarly, they believe that the continuous daily supply of PROTEINS, although from differenttypes of food (EGGS, MEAT, FISH) causes damage to our health.In fact, doctors usually agree that, in adults, eating very few proteins or even avoiding having all 9essential amino acids (from which our body can build PROTEINS in about one hour), is linked tothe absence of chronic-degenerative diseases, and therefore to a longer life expectancy.It is still thought in Universities that the minimum daily requirement for adults is 60 grams ofPROTEINS for an individual weighing 70 kg, when, actually, the “security” daily dose issignificantly lower (10-20 grams of PROTEINS or less).When the gut needs to metabolize great quantities of proteinic food, it needs to use its mineralstorage to counterbalance the acidic pH caused by eating too many PROTEINS (meat, milk,cheese, butter, eggs...).When pH is HIGH, that is greater than seven, the solution is basic (that is NOT ACIDIC, “caustic”,that is, giving a burning sensation to the external urinary duct mucosae).When pH is NEUTRAL, that is, equal to seven, the solution is neutral (that is, NOT ACIDIC, NOTBASIC).When pH is LOW, that is, less than seven, the solution is acidic (that is, NOT BASIC, “caustic”, thatis, giving a burning sensation to the external urinary duct mucosae).When pH is low, that is acidic, our body will lose its alkalizing minerals while trying to restore theright biochemical balance (buffer system)….One of the most efficient buffer systems is that of buffer ammonia.42

Kidneys start producing ammonia, an alkaline substance (that is, not acidic), that significantlyincreases the pH of excrements still in the intestines that will later become faeces.Urine will noticeably have a strong smell of ammonia, and urination could even be painful, becauseof the caustic nature (highly basic pH) of the urine that is being eliminated.It is suggested to drink some acidulous fruit juice (blueberry, orange, lemon juice, etc…) that willbring the solution back to normal and eliminate the pain.A strong smell of ammonia in urine could mean that our body is running out of alkalizing minerals.Of course, our body can find other stocks of alkalizing minerals such as calcium, sodium andmagnesium, but by doing so these precious minerals will be taken from bones, later causing damageand causing, in the long term, arthrosis and osteoporosis.In turn, producing too much ammonia will cause in the long term a gradual but irreversible kidneychronic failure (demonstrated by the presence of proteins in urine).If our body does not have enough calcium and magnesium, it will take the required amounts ofthese minerals from bones, to guarantee adequate levels in blood. Then, our body will try and makeup for this lack of calcium and magnesium by creating bony deposits that reduce movement andlimit activities (arthrosis, arthritis). Magnesium and vitamin D (obtained thanks to sun exposure) arethe safest solution to avoid such diseases. Restoring the biochemical conditions of the complexsystem in a young adult can take only a few months; on the contrary, in an elderly adult more than ayear might be needed before pH (for example, salivary pH) goes back to being slightly alkaline.Intestinal DISBIOSISThe worst effect of eating too many proteins is intestinal DISBIOSIS, that is, the alteration of thenormal gut flora (saprotrophic gut flora), that is responsible for the fundamental processes in theassimilation of nutrition (natural vitamins) contained in fruit, vegetables, cereals, and legumes.The loss of these “good germs” is due to eating too many proteins, rich in essential amino acids (allnine of them), in vitamin B12, and in glucose (simple sugar) that are freely available in theintestine.Glucose, and the presence of All Nine Essential Amino Acids, are the necessary source to developthe “bad” gut flora, that is, the one that causes putrefaction.The human intestine has a volume of about 6 litres and an enormous surface of about 400-600square metres. From the throat to the anus, there are 150 very important lymphatic centres, wherewhite blood cells (lymphocytes) maintain immune defences. This area is called intestinal lumen, itis very rich in “good” and “bad” germs, and it can be considered to be the most dangerous andcrucial area of our body.In fact, the two lungs have a much more limited total surface (just 80 square metres). In an adult,the skin has a surface of no more than 2 square metres…This immense intestinal surface, then, marks the difference between a healthy condition anddisease.In vegetarians, 20-40% of fecal mass is made of “good” germs (enterobacteria, or symbiotic orsaprotrophic germs).These germs, however, are present in all individuals in the higher part of the intestines (first andsecond part of the small intestine: duodenum and jejunum).These germs belong to over 400 species. The following are among the most important:Bifidobacterium bifidum, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus lactis,Lactobacillus rhamnosus; others: Edwardsiella, Citrobacter, Providencia, Arizona, Escherichiacoli, Enterobacter, Serratia, Klebsiella, Pseudomonas, Shigella, Vibrio, Proteus, etc…43

Some subspecies of these germs are pathogenic (Vibrio colerae, Shigella dissenteriae,Pseudomonas aeruginosa).All these germs are aerobic. That means that they need oxygen to survive. They are the cause of theSYMBIOSIS between human body and germs that allows a good nutritional balance forassimilation of vitamins by the human body in exchange for an ideal habitat for these germs’proliferation.These bacteria are not damaged by a vegetarian diet, even though fruit, vegetables and spices arerich in germicidal, fungicide and parasiticidal substances (e.g.: Allicin, contained in garlic, onions,leek, radish….). In turn, these germs greatly help the body to digest, and therefore, to assimilate thethousands of natural vitamins contained in vegetarian food.In the first part of the intestine, fecal mass contains about 1 million germs per 1 gram of excrementmass. While fecal mass travels through the gut, its percentage of “good” germs (symbiotic orsaprotrophic germs) increases, sometimes reaching 10 million germs per 1 gram of faeces.In the lower part of the intestine (colon), however, colonies of germs that are completely differentfrom the “good” ones start forming. These are the putrefaction germs: they can survive evenwithout oxygen (Bacteroides, Pepto-streptococcus, etc…).The quantity of these germs present in fecal mass increases dramatically, reaching 1 billion to 100billion “bad” germs per gram of fecal mass.These “bad” germs should only exist in the final part of the intestine, but unfortunately someincorrect eating habits help these germs in “going up” the intestine, reaching areas where theyshould not proliferate, such as for instance Helicobacter pylori that causes gastritis and gastric ulcerin the stomach.The abnormal proliferation of these “bad” germs takes place when we eat too many proteins and toomuch glucose, which gives them nutrition.Milk, cheese and other dairy products are responsible for this as well. Casein, contained in milk anddairy products, helps reducing the amount of oxygen in the intestine, thanks to its ability of“gluing” the intestine’s walls together (thus reducing dramatically the intestinal volume availablefor the assimilation of natural vitamins).The importance of “bad” germs becomes the cause of diseases in the fact that they replacethe“good” germs (symbiotic or saprotrophic germs).Thus, the human body cannot assimilate the precious natural vitamins properly.The presence of putrefaction germs then paves the way for fungi (candida), that in turn pave theway for intestinal parasites (worms).The presence of intestinal parasites (worms) is very common, although it is greatly underestimated.Laboratory tests searching for these parasites in faeces are not reliable. On the contrary, an easy-toobtainblood value is the percentage of EOSINOPHILS in the Hematocrit.Food intolerances, allergies (including asthma) and the majority (maybe all) of autoimmunediseases are, or could be caused (etiopathogenesis) by the presence of parasites (worms) in theintestine.In ASTHMA, allergies and food intolerances, the percentage of EOSINOPHILS is higher than 2%.This value is a limit that should never be trespassed.In allergies we find Immunoglobulin E (IgE), that on the contrary is not present in foodintolerances.44

Asthma, allergies and food intolerancesIn contrast with many allergologists, the author thinks that both food intolerance and allergies(including asthma) can be explained in the same way: immune unbalance caused by intestinaldisbiosis.However, for these patients it is necessary to eat proteins at least weekly. Once a week they canhave fish, organic meat or organic eggs. This will avoid dangerous anaphylactic shocks, in case ofincorrect or missing “food rules” in the first phase, when patients start following a vegetarian diet.This is true especially for vitamin F, that needs to be taken regularly to avoid allergic reactions.On the contrary, milk and dairy products should not be eaten for a long time.As far as white sugar, brown sugar and yeasts (bread, pizza, beer) are concerned, they should not beconsumed for a long time.As far as GM soybean and GM sweetcorn are concerned, they should be forbidden by the law (seefurther).Autoimmune diseasesThere are many very well known and studied autoimmune diseases, which Official Medicine can donothing about, apart from administrating cortison and other “symptomatic” drugs, which only treatthe disease’s symptom, without treating its cause. The following is a short list of the most commonautoimmune diseases.Central Nervous System: Multiple Sclerosis (?); Myasthenia gravis.Eyes: phacoanaphylactic uveitis, sympathetic ophtalmia.Salivary glands: Sjögren’s syndrome.Thyroid: Hyperthyroidism (Graves-Basedow disease); Hypothyroidism (Hashimoto’s chronicthyroiditis);Parathyroid glands: Hypoparathyroidism.Lungs: Pulmonary fibrosis of various autoimmune diseases, or allergic alveolitis of various origin(probably primitive pulmonary fibrosis, Hamman-Rich syndrome).Heart: Endomyocardial fibrosis.Stomach: atrophic chronic gastritis with pernicious anemia.Pancreas : Type 1 Diabetes Mellitus, or juvenile diabetes.Liver: some forms of biliary cirrhosis.Intestine: Coeliac disease, Whipple’s disease, protein losing enteropathy, Crohn’s disease,granulomatose colitis (Crohn’s colon disease), hemorrhagic rectal colitis.Adrenal glands: primitive adrenal gland atrophy.Kidneys and lungs: Goodpasture’s syndrome, chronic proliferative glomerulonephritis.Testicles: male sterility.Joints: Rheumatic disorder, Rheoumatoid polyarthritis, ankylosing spondylitis.Collagen: Systemic Lupus Erythematosus (SLE); polyarthritis nodosa, dermatopolymyositis,scleroderma, mixed connectivitis, sarcoidosis (suspect, probably coming from herpesvirus).Skin: pemphigus and similar diseases.Blood: autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura.Note 1: past long-term therapy with cortison can affect therapy for these diseases in a negative way,as reported in texts about gersonian-therapy or similar therapies ( 749 ).Note 2: therapy for Myasthenia gravis must be followed by specialists, as some life saving drugsare needed: the patient indeed constantly risks medical emergency.45

Malignant tumoursTumours such as cancer, sarcoma, lymphoma and leukaemia can arise faster if the immune defencesare lower (SEE Chapter 9) and if at the same time natural vitamins that could eliminate old cells arelacking (SEE Chapter 6 and Chapter 7).Other diseasesOther diseases (about which the author prefers not to express an opinion at the moment) could becaused by the presence of parasites, even only in part. These diseases were pointed out by someGerman studies in the 1920s and 1930s, and refer to neurological or psychiatric diseases. At themoment the validity of those studies cannot be judged, even though it is possible that theneurotoxins produced by intestinal parasites (worms) could actually affect the Central NervousSystem.Altered impermeability of intestinal wallsAnother reason why it is so easy for putrefaction germs to pave the way for fungi and subsequentlyparasites (worms), causing lower immune defences, is an altered permeability of the intestinal wallsfor putrefaction toxins. This happens if vitamin F is chronically absent in food, as stated by DoctorKatherine Kousmine many decades ago.Taken from: Katherine Kousmine: Save your bodies!“…If we go back and look at the history of our industrial society, and the changes it has brought about in nutrition, wecan see a huge mistake: the importance given to industrial fat substances, whether solid or liquid, artificial or inert.These are industrial fat substances that cannot repair cells, nor can they ensure normal structure and impermeability tothe tissues of our body, while this happens with natural fat substances, whether noble or essential, that are of vitalimportance for us.Since the normal tissue impermeability is lost, it is easier to be attacked by toxins, infections or allergies. Immunedefences are taken over and the immune balance is broken. But vitamin F (cis-cis linolenic acid) ensures the rightimpermeability of cell membranes and especially intestinal cell membranes, and makes up the main constituent thanksto which our body synthesizes anti-inflammatory prostaglandin PGE1.Eliminating these disturbing industrial fat substances and substituting them with oils rich in vitamin F (that arebiologically active, as they are cold-worked) could restore the normal tissue impermeability and so the correctproduction of PGE1. In this way, the normal immune balance would be restored, no matter what the symptoms of thisbalance’s alteration are. This is easy to observe in patients. Of course, restoring will be faster if no type of fat substanceis present: fat substances increase the need for vitamin F and thus they increase its lack as well…”46

Chapter 1.c: FATS and OILS (“Fatty acids”)Looking at Table 1 (Chapter 1.a) you will notice that oils are extremely rich as a source of energy(900 Kilocalories per 100 grams olive oil, sunflower oil, flax oil, grape seed oil, corn oil, etc). Fatsare very rich in energy as well.Chemically speaking, both can be considered to be “fatty acids”.There are “essential” oils and fats that contain vitamins (vitamin E, vitamin F, etc…). They arecalled “essential” because our body is not able to synthesize them.However, in the modern world we talk a lot about severe health problems linked to a diet rich in fatsand oils. Actually, the problem needs to be further explained.Chemically speaking, fats and oils contain three types of “fatty acids”:Saturated fatty acids (dangerous for health);monounsaturated fatty acids (not dangerous for health, can contain vitamins);polyunsaturated fatty acids (not dangerous for health, can contain vitamins).Saturated fats, or “bad” fats, are present in most animal fats, in margarine and in fats used in pastryshops. GM food has been recently suspected to contain them as well ( 1207 ).Saturated fatty acids, or “bad” fats, cause very severe alterations to cell membranes. They replacevitamin F (“good” fatty acids), and cause severe forms of cell wall impermeability for manysubstances like glucose (that might cause Type 2 Diabetes), apoptotic vitamins (that might causecancer and tumours in general), and other substances that are vital for cells, such as vitamin C (thatmight cause heart attack, strokes etc).On the contrary, unsaturated fats (“good fats”) are made of cis-cis fatty acids, that are typicallycontained in cold-worked vegetable oils.Unsaturated fats (vegetable oils) are present in many plant seeds (SEE Table 2), and in someanimals, such as some fat fish that live in cold waters (salmons, herrings).Fatty acids are vital for muscle cells to produce energy for them during physical activity and torelax them ( 1208 ).Furthermore, “good” fatty acids control blood coagulation ( 1209 ).They also influence the release of CCK, a hormone that tells our brain that we ate enough and thatwe should stop eating ( 1210 ).They contribute to maintaining conduction speed in motor and sensory nerves as well ( 1211 ).They can keep our skin healthy ( 1212 ).They reduce high blood pressure ( 1213 ).They reduce lung cancer (Pardini R.S.: Nutritional Intervention with Omega-3 Fatty Acids in a case of MalignantFibrous Histiocytoma of the Lungs, Nutrition and Cancer 2005, 52 (2) , pp.: 121-12947

It is useful to give a bit more detail about the vitamins contained in these oils.Alpha-Lipoic AcidAlpha-lipoic acid is an essential fatty acid that contains organic sulphur (as it is organic, that is,linked to biological molecules, it is not toxic). It directly helps making brain, muscle and skeletonenergy available during physical activity ( 1208 ), controlling diabetes as well ( 1214 ).Alpha-Linolenic AcidAlpha-linolenic acid is a cis polyunsaturated fatty acid present in cold-worked flax seed oil. It istransformed into EPA and DHA (Omega 3 fats), that are difficult to find in food.Table 2: percentage of vitamins contained in oilsFlax Seeds PumpkinSeedsSoyabean(NO GM)Sunflower(NO GM)Walnuts(NO GM)Rice(NO GM)Omega-6Linolenic Acid15 45 42 65 50 65Omega-3 54 15 11 5Linolenic AcidMonounsaturated 22 32 32 24 29 24fatsSaturated fats 9 8 15 11 16 11ValueExcellentomega 3Excellent forvitamin EGood Excellent Good Good iforganic, coldworkedOmega-6Linolenic AcidSafflower Grape Seed Sweetcorn Extravirgin Sesame Rapeseed(NO GM) Olive(NO GM)70 72 54 9 45 30Omega-31Linolenic AcidMonounsaturated 18 16 29 74 45 50fatsSaturated fats 12 12 17 16 13 10Vitamin E in mg 34 ? 14 12 1,5 11Value Good Good Inadvisablefor MultipleSclerosisExcellent forvitamin EGood Good if doesnot containerucic acidOmega-6Linolenic AcidAlmonds PeanutsPalm Palmist Coconut(NO GM)17 29 9 2 4Omega-3 68 56 44Linolenic AcidMonounsaturated 15 15 48 18 8fatsSaturated fats 19 19 80 88Value Advisable Inadvisable Negative Negative Negative48

Chapter 1.d: VITAMINSWe eat food because we are hungry and, instinctively, we prefer a certain type of food rather thananother one.The SMELL and TASTE of what we eat are important themselves, but very often we underestimatethem because of visual appearance. A beautiful apple will look better than another one for us, butthen we will notice that the beautiful, shiny and colourful apple is totally TASTELESS.Then, what is “TASTE”?Essentially, “TASTE” is the I.D. of the food we are eating, and it often tells us which and howmany “vitamins” are contained in it. If food is warmed up, cooked or left for a long time, it will loseits “vitamins”.The amount of “vitamins” varies from 15,000 to 30,000. Vitamins are the basis of our health.The human race has always been tormented by diseases in the past. History calls some of them“incurable diseases”; in fact, they were defeated by simple vitamins.I will name here the GREAT “incurable” diseases:Scurvy (variable death rate, defeated by vitamin C);Pellagra (death rate 97%, defeated by Niacin or vitamin B3);Pernicious anemia (death rate 99%, defeated by vitamin B12 and folic acid);Beriberi (death rate 99%, defeated by Thiamine or vitamin B1).If we consider cancer a chronic-degenerative metabolic disease, cancer itself could be defeated byusing great quantities of natural vitamins, among which the most important would be vitamin B17(SEE Chapter 7).30,000 lost VITAMINS...Just as for monkeys, millions of years ago the human race lost the capability of synthesizing manyvital substances that could be found in fresh fruit and vegetables in African forests. Thesesubstances are essential for life and are nowadays called “vitamins”: they are dozens of thousands,and most of them are still being studied…The human species is similar to apes but it is different from a phylogenetic point of view, as thenumber of chromosomes is different (46 and 48 respectively: this would exclude direct descent).Moreover, for millions of years both populations of hominids lived near a source of fresh water andate almost exclusively raw vegetables, fresh and dried fruit, wholemeal seeds, fish, and smallquantities of meat ( 1288 ). If we consider all this, we can theorize that human biochemistry, too, haslost the intracellular mechanisms that were typical of prosimians and their most phylogeneticallysimilar ancestors. Thus, humans ended up losing the ability to synthesize complex anti-oxidantenzyme chains that are typical of DNA repair systems.From an evolutionary point of view, losing their ability to synthesize key-enzymes for intracellularrepair processes was an advantage. Indeed, it allowed saving enzymes for synthesis and forbiochemical energy: nature made thousands of anti-oxidant and intracellular repair substancesavailable in food, substances that we now call "vitamins"......49

Thus, this explains why prosimians themselves had already lost the ability to synthesize vitamin Cseveral millions of years earlier: they would find vitamin C in their usual food, that is fresh fruitgrowing on trees in forest. This change took place before they evolved into transition animal speciesand finally into today’s monkeys. Therefore, it is reasonable to think that this change took place inthe species today’s mankind descends from, too.Note: on a DNA level, man and chimpanzee are twin species, as if their evolutionary division took place about 5 billionyears ago, during Eocene; on the contrary, on an anatomical-morphological level they pertain to very different species,as if their division took place about 12-15 billions years ago. So, in evolutionary terms, today’s human DNA shouldhave been quite different from the present-day chimpanzee, following the long process of evolution of about 12-15billion years, according to the requirements of slow and casual genetic changes that are necessary to determine the deepchange in anatomy and morphology that differentiates the human race from chimpanzees. On the contrary, the DNA ofhumans and chimps is identical. So the ten great genetic changes in human DNA are interesting because theydifferentiated humans from chimps and allowed the evolutionary leap towards men. The combination of casual eventsof these ten important genetic changes in human DNA are still being studied. What Mangiarotti ( 1287 ) reported inmedical literature about this paradox of evolution is then very interesting. SEE Allegated 27A simple tomato (Solanum lycopersicum), just picked from a plant in soil which is absolutelydevoid of any toxic substances, can contain as many as 10,000 natural different chemical substances(phyto-chemicals), each of which is a vitamin, a co-enzymatic factor, an anti-oxidant, etc ....This is therefore true also for green leaf vegetables, fruit, vegetables, tubers, etc ...But, after only a week in a fridge, green leaf vegetables lose about 25% of their ascorbic acid, andafter a further week 80%. After only 3 hours in a fridge a fruit salad has practically lost all itsnutritive value.Therefore, a cancer patient absolutely must eat fresh vegetables, fresh fruit, fresh tubers and freshgreen leaf vegetables, that is, all products which are 'in season', and in good condition. Otherwise,as an alternative, frozen vegetables can be used, which are infinitely preferable to those comingfrom forced cultivation in greenhouses, which produce modest amounts of anti-oxidant activefactors.Choosing fresh products is therefore the basic rule to follow, but it alone is not sufficient for theaims described in this study .....It is necessary to choose another source of food for cancer patients (providing they are NOTundergoing chemotherapy, but are undergoing immune-therapy as described in this study): thesepatients must, in fact, be fed with food which is absolutely devoid of any pesticides, herbicides,glues, waxes, laquers, anti-budding liquid, ethylene oxide and others.Furthermore, many patients and their families do not remember or do not know when the variousvegetables are in season.The use of fertilizers prevents plants from absorbing important minerals, such as Selenium, from thesoil. Fruit is picked before it is ripe, and is then put in cold storage.In this way the most important principle is lost, by which the fruit reaches its maximum vitaminpotential as it ripens fully on the branches of the trees. Finally, it must be remembered that themajority of co-enzymatic factors contained in fruit are to be found just under the skin, which inmost cases is lost because the fruit is peeled.Furthermore the widespread use of nitrogen fertilizers, used to increase the production ofvegetables, leads to an increase in the nitrogen content in the vegetables. We then have the seriousproblem of vegetables which have a high nitrogen content, which if they are not preserved in thecorrect way or if they are not eaten shortly after being picked, will produce Nitrates and Nitritesinside the vegetable, with potential toxic and immune-depressive consequences especially forcancer patients who are undergoing Immune-Therapy, as described in this study.50

Finally it must be remembered that environmental pollution has caused an increase in heavy metalsin agricultural land in Europe; everywhere there are metals such as Nickel, Lead, Chrome andCadmium. The presence of these chemical agents mean that plants and fruit absorb much morewater compared to those grown in non-polluted areas: this explains the change in flavor, smell andeven consistency of the fruit itself, a fact easily noted by anyone. Subsequent chemical analysis inthe laboratory shows there is an effective loss of nutritional value in fruit, green leaf vegetables andvegetables before they have even been picked. In Europe these losses are serious, estimated at about50%-70% for established components such as vitamin B6 in green beans, Vitamin C in spinach orstrawberries (a loss that rises to 90% in bananas imported from abroad). Moreover, in over 200studies, the relationship between the reduced consumption of fruit and fresh vegetables and cancerhas been highlighted ( 624 ) http://www.mednat.org/alimentazione/Nacci_vitamine%2023.pdf ;http://www.mednat.org/alimentazione/Nacci_vitamine%2024.pdf , and the particular protective role ofVitamin E has been stressed: vice versa, isolated supplementation of single vitamins, particularly ifthey are synthetic, has sometimes shown paradoxical results, with a relative increase in theincidence of tumors: complete and natural food is really the best source of vitamins and of otheractive principles for a normal diet, and, especially, for the anti-oxidative diet for cancer patients aswill be discussed hereafter.The author therefore maintains that mankind is actually lacking a large percentage of about 13,000estimated forms of chemical complexes present in the principle nutrients existing in nature, and to alarge extent found together in fresh vegetables, fresh fruit, seeds, and shellfish (mussels, clams andoysters).Of these, the substances known and considered essential for the human diet in the normal universitycourses of Medicine and Surgery, Pharmacy, Chemistry and Biology (vitamins, pro-vitamins,enzymatic co-factors, essential oils, essential amino acids and mineral salts), do not exceed thefigure of 0.5% of the whole number of phyto-chemical substances indicated above, of about 13,000.It is therefore time to reconsider our “food safety” with regard to "vitamins".Furthermore if one takes into account the high turnover of the necessary enzymatic processes, onearrives at the conclusion that eating fresh vegetables and/or fresh fruit only twice a day is just notenough, particularly for a cancer patient, because the anti-oxidative defenses of the white bloodcells and of other healthy cells cannot remain without vital co-enzymatic factors.This can be easily proved, for example, by measuring the ratio of 8-hydroxy-deoxyguanosine ineach cancer patient undergoing therapy at home.51

VITAMINS (In alpahabetic order):Aminoacid NOT found in proteins: MimosineAnthraquinones: Aloctin A, Aloctin B (Barbaloin), Emodin, and OTHER;Ascorbic acid (vitamin C)B group : B1 (Thiamine), B2 , B3 (Niacin), B4 , B5, B6, B7, B8 (Biotin) B9 (Folic acid) , B10, B11, B12, B13,B14, B15, B16, B17 (Amigdalin), ….and OTHER….Note: “Laetrile” acronym for “LAEvomandeloniTRILE-glucoside”) as Amygdalin: Laetrile has two molecules ofglucose, Amygdalin has more. Indeed, the chemical structure of Laetrile is D-1 mandelonitrile–beta-glucuronide, whilefor Amygdalin it is D-mandelonitrile-bi-glucoside.Carotenoids: a family of pigments with at least six-hundred members, as Axerophthol palmitate, alpha and betaCarotene, trans-Retinoic acid, Lycopene, Lutein, Canta-xantine, Cripto-xantine, Zea-xantine, ….and OTHER …E group: This liposoluble substance consists of a group of various components, called Tocopherols. Seven of theseexist in nature; alpha-Tocopherol, beta-Tocopherol, gamma- Tocopherol, delta-Tocopherol, epsilon-Tocopherol, zeta-Tocopheros and eta-Tocopherol.F group: polyunsaturated fatty acids : arachidonic acid, Linoleic cis-cis natural acid (vitamin F1) as: alpha-lipoicacid, alpha-linolenic acid, ….and OTHER…..Flavonoids is a group of more 4.000 polyphenolic compounds. These compounds possess a common phenylbenzopyronestructure (C6-C3-C6) , and they are categorized according to the saturation level and opening of thecentral pyran ring, mainly into seven main groups: Flavonones, Flavanols, Flavones, Flavonols, Flavanonols, andIsoflavones.Es.: Acacetin, Apigenin, Baicalein, Baicalin, Bilabetol, Biochanin A, Campherol, Catechin, Chrysin, Citrin, Daidzein,Diosmin, Epicatechin, Epigallocatechin, Epigallocatechin-3-gallate, Equol, Eriodictyol, Fisetin, Formononetin,Galangin, Gallocatechin, Genistein, Genistin, Ginketol, Gitogenin, Glycitein, Hesperidin, Hyperoxide, Isoamnetin,Isoginketol, Kampherol, Liquiritin, Luteolin, Morin, Munetone, Myricetin, Naringenin, Naringin, Nobiletin,Pychnogenol, Quercetin, Robinetin, Ruscogenin, Rutin, Silydiamin, Silymarin, Silychristin, Tangeretin, Taxifolin,Wogonin , and OTHERIndole glucosinolates : as Indol-3-carbinol, and OTHER (Brassica vegetables); conversion to isothiocyanatesIsoprenoides : Abscisic acid, Acorenone, Alloaromadendrene, Aromadendrene, Bergamotene, Bisabolene,Borneol, Bornyl acetate, Isoborneol, Cadinene, Camphene, Caranol, Carene, Carvacrol, Carvone, Pinocarvone,Caryophyllene, Cedrine, Cineole, Cinnamaldehyde, Cinnamate, Citral, Cyclocitral,, Citronellal, Citronellyl acetate orbutyrate or propionate, Copaene, Cresol, Cubebene, Cymene, Damascenone, Elemene, Estragol, Eugenol, Farnesene,Fencone, Geraniol, Germacrene, Hotrienol, Humulene, Ionol, Ionone, Isopinocamphone, Isopulegol, Limonane,Linalool, Longifolene, Mentol, Neomenthol, Menthone, Isomenthone, Murolene, Myrcenol, Myrcene, Myrtenol, Neral,Nerol, Nerolidol, Nootkatone, Ocimene, Ocimenol, Perillaldehyde, Phellandrene, Pinene, Pinocamphone, Piperitol,Piperitone, Pristane, Pulegone, Sabinene, Sabinol, Santalol, Selinadiene, Selinene, Sinensal, Styrene, Terpinene,Terpineol, Terpinolene, Thymol, Tricyclene, Vanillin, Valencene, Verbenone, Vitispirane, …and OTHER…Lecithins : as Alexin B, ….and OTHER52

Minerals (organic) : organic Boron, organic Calcium, organic Chromium, organic Germanium, OrganicIodine, organic Iron, organic Magnesium, organic Manganese, organic Molybdenum, organic Selenium, organicSilicium, organic Vanadium, organic Zinc, …. and OTHER….Note:allyl Sulfur (an organo-Sulfur compound) (*)Diallyl sulfide [DAS], (an organo-Sulfur compound) (*)Diallyl disulfide [DADS], (an organo-Sulfur compound) (*)Diallyl trisulfide [DATS], (an organo-Sulfur compound) (*)Germanium sesquioxideManganese Superoxide Dismutasis (SOD),Selenium derivatives (sodium Selenite, Seleno-DL-Methionine, Se-methyl-selenocysteine)(*) which are decomposition products of AllicinOxindole alkaloids: Pteropodin, Specrofillin, Hystopteropodin, Uncaria F, Isomitrofillin, …and OTHER…..Saponins : Ginsenoides, Saikosaponin D, ….and OTHER….Stilbenes: is a group of polyhenols : Resveratrol, …. and OTHER….Styryl-lactones : Altholactone, Goniothalamin, ….and OTHER….Tannins: is a group of polyhenols; tannins are divided into 2 chemically distinct groups:1) the condensed tannins (Proanthocyanidin)2) the hydrolysable tannins (as hydrolysable Ellagitannins, such as Woodfordin C (macrocyclic ellagitannindimmer), Oenothein B, Camellin B, …..and OTHER…..NOTE: Anthocyanins: Peonidine-3-glucoside, Cyanidin-3-glucoside , ….and OTHER….Terpenes: Alisol B acetate, Atractylon, Atractylenolides, Betulinic acid, Bisabolol, Boswellic acid, Carnosic acid,Ferutidin, Ferutinin, Myristicin, Oleanolic acid, Parthenolide, Pomolic acid, Tymoquinone, …and OTHER…Vanillys-phenols : is a group of polyhenols; share structural similarities possessing both the vanillyl (4-hydroxy3-methoxyphenyl) moiety and the ketone functional group in their structure; Paradols, Gingerols, Yakuchinone B,Curcumin (diferuloyl methane), Capsaicin (homo-vanillic acid derivative : 8 methyl-N-Vanillyl-6-nonenamide),…andOTHER….:….and OTHER….53

Chap 1.2: “Herb-Therapy must not be prohibited”The European Commission (the Internal Market, Tourism and European Community ConsumersCouncil) has proposed a directive on vitamin integrators, natural and nutritional products in theEuropean Union.The European Commission basically intends to:1) strictly limit the maximum dosages of vitamins and minerals allowed in integrators ( article5 of the proposed directive );2) eliminate from the market all the sources of vitamins and minerals which are not mentionedin a limited list of “permitted chemical substances” (SEE second attachment to the proposeddirective );3) eliminate herbal products from free sale in Europe, and oblige them to be registered as“traditional herbal medical products” (the Commission’s proposed directive on traditionalherbal medical products - 3 rd draft, May 2001 );4) prohibit all information on preventive and curative properties of vitamins and minerals,considering such information illegal if in any way related to a product.The agreement will be an incentive for what seems to be the Commission’s plan to eliminate Phyto-Therapy’s therapeutic alternatives to therapies based on chemically synthesized medicines.This Project of the European Commission aims to favor those who are making a profit from themain illnesses of deficiency which are now widely spread across the western countries (cancer,cardio-vascular diseases, diabetes, “american” obesity, hyper-tension, Alzheimer's, Parkinson’sdisease, Acquired Immuno-Deficiency Syndromes, etc…) that is to say those companies whichmake their profits from illnesses, instead of health: in other words, the major chemical andpharmaceutical industries.Cancer, which was not very common until 100 years ago, is nowadays perhaps the main source ofprofit compared to other illnesses. The continuous increase in cancer is a clear confirmation of thefact that the Cartel of the Pharmaceutical Multinationals is far from keeping its promise, that is toimprove everyone’s health: not only has the Cartel not gradually eliminated illnesses as it hadpromised, but the actions and products of the Cartel itself have sometimes been the direct cause ofthe tremendous increase in illnesses with which we are presently faced.Nowadays many doctors opt for “alternative” treatment techniques, based on the assumption that itis exactly the deficiency of thousands of vitamins that causes serious illnesses such as cancer, andother deficiency diseases. But these doctors are daily exposed to harassing attacks.It can therefore be maintained that the Pharmaceutical Multinationals act through internationalinstitutions such as the European Commission and the Codex Alimentarius (a branch of the UnitedNations Food and Agricultural Organization), to pursue their more or less illicit money-makingactivities: for example, they have established the RDAs ( Recommended Daily Allowances ), alsoknown as PRI’s ( Population Reference Intakes ), an acronym which indicates the quantities ofvitamins and minerals, that is, the quantities of nutriments that are absolutely scurvy and beriberi.But the recommended quantities are not sufficient, nor have they ever been thought of for theprevention of the deficiency diseases mentioned above (cancer, cardio-vascular diseases, diabetes,“american” obesity, hyper-tension, Alzheimer's, Parkinson’s disease, Acquired Immuno-DeficiencySyndromes, etc…), that is, to guarantee good health by enforcing the organism’s defenses.Nevertheless, the European Commission’s proposal for a directive on vitamin integratorscontemplates “maximum levels of dosage to be determined according to an analysis of risks, carried54

out with scientific methods, taking into account the contribution of vitamins and minerals fromother nutriments…”, and also the “Population Reference Intake”, according to the declarations ofcommissioner David Byrne.This book intends to ask the following questions:1) Why do they want to protect us from the obviously inexistent dangers of alimentaryintegrators, when millions of people die every year because of the well-known “side effects”of chemical and pharmaceutical medicines?2) Why will the “scientific evaluation” of the dangers said to be hidden in these innocuousbiological substances be carried out by the same scientists that are responsible for havingintroduced on the market highly toxic medicines that kill millions of people every year?The answer could be the following: the directive proposed by the European Commission has beenformulated on the suggestions of the Pharmaceutical Cartel, and it is the last attempt to eliminatethe growing competition of biological substances provided by natural and nutritious productsincluding alimentary integrators, consisting of over 13.000 essential vitamin principles.Scientific literature is full of studies that prove the benefits for health and the preventive propertiesof vitamins, minerals and other substances with biological activity found in alimentary integrators.An adequate supply of vitamins and other substances with biological activity could prevent millionsof deaths every year, and cure many illnesses currently considered incurable, such as cancer andmany other pathologies (to be published in future on this site ).Therefore this book says:NO to the European Commission’s proposed directive on integrators, especially in its presentrestrictive draft;NO to the restriction on maximum dosages of integrators which have not been proved to be thecause of real, not imaginary, health problems;NO to the costly “pharmaceutical evaluation” of natural biological products intended to eliminatefrom the market all substances which have not been approved;NO to the need for the “demonstration of non-toxicity” of these natural biological products, whichoften requires experiments on animals;NO to the registration of all natural products based on herbs as “medical product” or as “herb-basedtraditional medicine”;NO to the prohibition of the publication and distribution of scientific information, even if connectedto specific products, regarding the effects of natural substances with biological activity.It declares that the important role of natural substances and nutrients with biological activitycontained in alimentary integrators in maintaining good health and preventing illnesses should berecognized, and should receive the consideration it deserves in any legislation which sets itself thegoal of regulating the sale and distribution of these products.It declares every citizen’s freedom of choice in matters of health.55

Europe First To Ban SupplementsFrom INTERNET: http://curezone.com/forums/m.aspIn August 2005 everything in Europe is about to change due to the EU Food Supplements Directive(FSD). Banned items will include natural vitamins such as mixed tocopherols (natural vitamin E),carotenoids and B-12 methylcobalamin, all forms of Sulphur, Boron, Vanadium, Silicon and mosttrace elements, the most readily absorbed and safest forms of Calcium, Magnesium, Zinc,Selenium, Chromium and Molybdenum. It will severely limit the doses of vitamins and will removeall high-dose products from the market. It will include future restrictions on nutrients such as fattyacids, amino acids, enzymes, probiotics, phytonutrients, etc.The directive will dramatically limit future innovation in the supplements industry, and seriouslyimpact retail outlets, complementary practitioners and consumers who choose to take responsibilityfor their own health and let food be their medicine.Here, again, is where it affects us: the draconian EU Directive goes far beyond denying mostEuropeans access to safe nutritional supplements; it is about to be used as the blueprint forestablishing international dietary supplement laws at Codex, which our government in itsquestionable wisdom has made us part of. Codex will outlaw or severely restrict virtuallyeverything millions of us have grown accustomed to using safely every day. National borders don'tmean much anymore; we are witnessing the rapid unification of the world into a new globalgovernment with Europe at the helm. When the World Trade Organization (WTO) was given teethto enforce international trade laws in the early 1990s, all WTO member nations agreed toharmonize their trade laws to new international laws so every nation operates by the same set ofstandards. Since then, every single ruling that the WTO has made has gone against the environment,against the public health, against consumer rights, against labor rights, and against human rights.Although activists protested against the WTO, most people were unaware that it would eventuallylead to an incremental attack on all of our food supplements around the world. Most supplementcompanies have simply gone along with the advice from their pharmaceutically dominated tradeassociations.Germany, the largest pharmaceutical manufacturing nation on earth, currently dominates the EUwhich hosts the Codex Committee on Nutrition and Foods For Special Dietary Use, and is leadingthe charge to railroad our dietary supplement laws into international harmonization. The EuropeanUnion is the blueprint by which our would-be rulers intend to form a global totalitarian state. Whatthey're doing with the EU is their first project; they're trying to make and control similar regionaltrading blocks all over the world. For example, they're trying to create the Free Trade Area of theAmericas (FTAA) through which they're trying to harmonize the laws between Canada, the U.S.,Mexico, and Central and South America.The Alliance for Natural Health (ANH), a consumer advocacy group based in Britain, was recentlygranted the green light to challenge the Food Supplements Directive at the last minute; however,very rarely has a EU Directive ever been overturned and in this case, it would be a historic eventconsidering the pharmaceutical interests backing its implementation. Resources are very scarce butthey've got to keep the lawsuit going to overturn the Directive before it's too late. They've hired atop legal staff and they are girded for battle in a EU Court. With the EU expanding by ten morenations in early 2004 to a combined total of twenty-five member nations, and with heavy pressureto finalize a Codex vitamin standard, the situation is critical. If the FSD is not overturned now, withEurope's ever-expanding power it's very possible that there will be enough countries onboard tooverrule the protests of the few countries at Codex, where many parts of the FSD will be used whennew international vitamin laws are codified. Once a Codex vitamin law is finalized, it will56

supercede any member country's supplement laws. The only way for a country to truly protect itsvital interest on this and other matters is to get out of the U.N. and the WTO entirely, a 'best case'scenario that nobody realistically sees happening.In the 21st century we live under siege. There are concerns about pesticides, herbicides, antibiotics,GM,mobile phones, microwaves, amalgam fillings, falling sperm counts, mad cows, MMR - evenmilk. Farmed salmon is a Trojan horse for carcinogens. Obesity and diabetes are on the march.There is a mass of documentation on all this. So what is the European Commission's big idea? 'Let'sclamp down on vitamins and minerals.'In order to prevent a sinister one-world government from mining people as the resource, usurpingour natural freedoms and dictating our moves, we must pony up and donate to the ANH so they canmake a decent legal presentation; if we don't do it for ourselves, how about our grandchildren andthe rest of society? Go online to www.alliance-natural-health.org and make a donation. Or suffer.---Duncan Crow---http://www.alliance-natural-health.org(Duncan Crow, Wholistic Consultant. Canada)http://curezone.com/forums/m.asphttp://curezone.com/forums/m.asp?f=237http://curezone.com/forums/m.asp?f=237&i=597www.db.europarl.eu.int/ep6/owa/p_meps.short_listSue CroftConsumers for Health Choice ~11 Green Pastures RoadWRAXALLNorth SomersetBS48 1NDEnglandTel.: +44 (0) 1275 852597Fax: +44 (0) 1275 858702Cell.: 07860 286425Web: http://www.healthchoice.org.uk57

Chapter 2: The ideal diet for cancer therapyBasically, the ideal diet is rich in in-season fresh fruit vegetables (from 10 to 15 portions a day foreach); in particular, as regards vegetables, the following daily plan should be followed:1) Bulbs: Allium sativum (garlic), Allium cepa (onion), etc...2) Florets: Brassica oleracea italica (broccoli), Brassica oleracea botrytis (cauliflower, etc..)3) Vegetable fruits: Solanum lycopersicum (tomato [only small ones]), Cucurbita pepo(zucchini/courgettes, etc...) ...[NOT pumpkin (sugar beets )].4) Vegetable leaves: Spinacia oleracea (spinach), Lactuca sativa (lettuce), etc...)5) Vegetable roots: (Daucus carota (carrot), Pastinaca sativa (parsnip), etc...[NOT Beta vulgaris(sugar beets )].6) cereals (SEE later) [NOT Zea mays (sweet corn, maize) it’s a GMO risk; NOT Oryza sativa(rice) for GMO risk;7) Tubers: Solanum tuberosum (potatoes), Brassica rapa (turnip), etc...) [NOT Solanum tuberosumfor GMO risk ].8) Vegetable stems: Asparagus officinalis (asparagus), Apium graveolens (celery), etc... [Do NOTeat raw Asparagus officinalis and/or Apium graveolens].Chap. 2.2.: Food combinations (cereals + legumes)It is also important not to eat pasta (Triticum durum, vulgare, spelta) or Sweetcorn (Zea mays), orrice (Oryza sativa), or bread together with pulses, because doing so there is an integration of the 9essential amino-acids (the 8 contained in the cereals + the 8 contained in the pulses), with anutritional effect similar to the one obtained by eating meat (SEE chapter 1.b: Proteins)ALL the essential amino acids are: Valine, Isoleucin, Leucin, Lysine, Methionine, Histidine,Tryptophane, Phenylalanine, Treonine.LEGUMES contain a lot of energy, and, potentially, a lot of proteins. They contain a lot of proteinsonly together with food containing the missing amino acid (usually Methionine).Note: Hippophae rhamnoides (Olivello spinoso) is rich of Lysine, as LEGUMES.Amaranthus hypochondriacus (amaranth) is rich of Lysine, as LEGUMESSecale cereale (rye, used in Gerson-Therapy) is rich of Lysine, as LEGUMES58

Chap. 2.3.: The dangers of GM foodThus, those that are dangerous for health are only GM legumes, as they have ALL nine essentialamino acids, as we already know for alfalfa ( 745,967 ), for GM soya, GM peas, ( 1011, 2006 ), for GMclover ( 1066 ), and GM beans. People must know what happens if they use these as food, because theresult is a nutrition full of proteins, and not only of energy. This is particularly important for peoplewho have chronic-degenerative diseases (cancer, diabetes, arthrosis, osteoporosis, cardio-vasculardiseases, obesity, etc). The hidden protein intake can nullify nutritional therapies based on avoidingproteins (they are based on totally eliminating MILK, MEAT, EGGS, FISH and YEATS from thediet).The problem is similar also for GM CEREALS, that were recently introduced in our nutrition. Theycontain the missing amino acid, usually Lysine.At the moment, there are three GM cereals being produced and sold in the United States and in therest of the world: SWEETCORN, RICE, and WHEAT.Although many patients are very careful about food labels, at the moment we cannot exclude thefollowing facts, based on failed therapy in some cases where the diet was correct:1) Rice sold in Europe presumably contains Lysine in good quantities, as opposed to organic rice. Italso seems that some rice brands sold in Europe also contain the pesticide toxin Bacillusthuringiensis (SEE below).2) Some brands of GM sweetcorn have already been officially introduced in Europe, but we don’tknow whether they were enriched with all essential amino acids or not, nor how they weremodified. It seems that they were modified introducing Bacillus thuringiensis, a pesticide toxicsubstance.3) At least one fifth of Italian PASTA is made with wheat coming from abroad, usually fromAmerica (“Panorama” magazine, 2004-2005): no-one can exclude that American flower containsALL 9 ESSENTIAL AMINO ACIDS.It would be interesting to study the pasta imported from America to check the presence of:a) ALL 9 ESSENTIAL AMINO ACIDS, by comparison with certified organic wheat (organicwheat contains little or no Lysine).b) Transgenic toxins (Bacillus thuringiensis).c) Transgenic viruses (SEE chap. 8), that are often used to make GM vegetables.The problem of WHEAT: the author expresses particular concern about wheat (Triticum durum),from which in Italy today we get both pasta and bread: patients suffering from cancer need a lot ofenergy (at least 2,000 kcal/per day) provided that it comes from food with no Vitamin B 12 andwithout ALL 9 Essential Amino Acids. That is NO animal product: Pasta, together with rice, is (orwas) the most suitable food for this. They have already started growing new varieties of wheat inthe USA, of the GM variety, the characteristics are not yet known. However it is feared that theymay have been enriched with Lysine as in American potatoes, American maize, and American rice.For this reason, the author expresses serious doubts on the introduction of cereals, pulses and othergenetically modified vegetables (often not even declared as such) onto the market that could contain59

ALL the ESSENTIAL AMINO ACIDS (9), thus effectively rendering Cancer no longer curable asdescribed in the present study.For example, it has been possible to trace from bibliographical data that the potato (previouslyconsidered a cure for tumors), is today absolutely counter-indicated, because the synthesis gene ofLysine has been inserted into it ( 689 ). This is an essential amino acid that the potato did not have,and a gene obtained from Amaranthus hypocondriacus (amaranth, tumbleweed) which is wellknown to be rich in this essential amino acid. The very same Lysine ( 685 ) has been introduced into alocal variety of potato in Israel, since 1992. In 1997, in the United States, human Casein wasintroduced into a North American variety of potato, thus making it complete with all the essentialamino acids ( 687 ).In 1998 Bacillus thuringiensis was transferred to potatoes by means of GMO technology, and thesewere fed to mice ( 1589 ) : the intestinal cells of these mice showed degeneration phenomena andlesions in the microvillus on the surface of the intestinal space; hyperplasia was present in half ofthe cells and of several nuclei; the thin basal plate of the intestine was damaged in various places;several damaged microvilli appeared with fragments containing endoplasmic reticulum; the Panethcells had a high degree of activation and contained a high number of secretory granules. [note fromthe author of this site: the resulting picture reminded one, at least to some extent, of ileitis fromrays, or “Baserga syndrome”, well known in the Marshall islands in 1954, where many civilianswere exposed to food contaminated by radionuclides of alpha and beta emissions, coming from thefallout of nuclear explosions].The genetic threat from this experimentation is very little debated with regard to its real problem( 689 ).If the patient manages not to destroy all of his/her own reserves of proteins in muscles, maintainingan energetic physical program, with long walks and exercise suitable to maintain good muscle tonethroughout the patient’s whole active muscular structure, then the organism will begin to look forprotein reserves which are not essential, such as fatty tissue and above all, the neo plastic tissuesthemselves.But particular attention must also be paid to other transgenic variants (GM) of plants used for food,which, according to the author, can no longer be used in a cure against cancer, because such plantsusually come from abroad and furthermore have been prepared in laboratories in American,Canadian or Japanese industries and are therefore suspected of being carriers of transgenic viruses(with a risk of transgenic diseases); of lacking the important vitamins needed to fight tumors andperhaps of being carriers of substances which inhibit apoptosis in diseased cells (SEE below).It is because of this that the author expresses serious concern about the introduction on the marketof cereals, pulses and other genetically modified vegetables (often NOT declared) which couldcontain ALL the ESSENTIAL AMINO ACIDS (Valine, Isoleucin, Leucin, Lysine, Methionine,Histidine, Tryptophane, Phenylalanine, Treonine) thus effectively rendering cancer no longercurable using the treatment described in this work, a work which in its ideals links up to the oldtherapy of Dr. Gerson, extending it to many other curative plants such as Aloe arborescens, forexample.The author of this study thus maintains that if GMO are liberalized, there will be the most seriousenvironmental disaster ever seen, because there will no longer be any possibility of curing cancerwith Gerson's diet, or with other food programs as described in this study, which alone were able tocure between 70% and 90% of patients, provided that there was no Chemo-Therapy ( 749,750,969 ).60

Chap. 2.4.: The importance of oilsOils must be produced by cold pressing olives, and must not be refined.Large use of Italian extra virgin olive oil, and oil of flax seeds (Linum usitatissimum).The latter must never be used for frying, but must be used only raw. Ideally, this is true also forolive oil, because of the vitamins it contains. True extra virgin olive oil is hard to find, because it isoften adulterated. For example, it is notorious that, at temperatures below zero degrees Celsius, onlytrue extra virgin olive oil completely freezes, while the adulterated one containing remains usuallyfreezes in little inhomogeneous spheres. Despite this, it is still being sold as “extra virgin oil”.Cold pressed flax seed oil is very important because of vitamin F, which is not present in extravirgin olive oil. The latter contains vitamin E, which is not present in cold pressed flax seed oil.To understand the importance of these two oils, further on you can find a short medical explanationabout the vital importance of these two vitamins.Chap. 2.5.: Spices, grass used in cooking but also in medicineThe following are useful spices (some of them carry out a specific anti-neoplastic function on animmuno-stimulating and/or apoptotic basis):Anethum graveolens or Peucedanum graveolens (dill),Hibiscus abelmoschus or Abelmoscythus moschatus (rosemallow),Angelica archangelica,Pimenta racemosa (Pimenta),Stirax officinalis (benzoin),Dryobalanops aromatica (borneole),Aniba roseadora (Bois de Rose),Melaleuca alternifolia (Tea tree)Melaleuca leucodendron or minor (Cajeput),Melaleuca quinquenervia or viridiflora (Niaouli),Cymbopogon nardus or citratus (cymbopogon),Foeniculum vulgare or sativum (fennel),Lavandula officinalis or angustifolia (lavender),Lavandula stoechas (French lavender),Myrtus communis (myrtle),Pinus mugo (mugo pine),Pinus sylvestris (scots pine),Salvia sclarea, Santalum album (sandal wood),Satureja montana or hortensis (savory),Lippia citriodora (verbena),Cananga odorata (Ylang-Ylang),Viola odorata (sweet violet),Pimpinella anisum (anise),Ocimum sanctum or tenuiflorum (basil),Cinnamomum zeylanicum (cinnamon),Elettaria cardamomum (cardamom),Eugenia caryophyllata or Caryophyllus aromaticus (cloves),Coriandrum sativum (coriander),Carum carvi (cumin),Carum nigrum or Nigella sativa (black cumin),Curcuma longa (curcuma),Artemisia dracunculus (tarragon),Melissa officinalis (lemon balm),61

Mentha species (mint),Origanum vulgare (oregano),Majorana hortensis (marjoram),Capsicum frutescens, fasciculatum or annum (cayenne pepper, paprika),Cochlearia armoracia (radish),Rosmarinus officinalis (rosemary),Salvia officinalis (sage),Schinus molle (Brazilian peppertree),Sinapsis arvensis or alba (mustard),Thymus vulgaris (thyme),Crocus sativus (saffron),Piper nigrum (black pepper),Zingiber officinalis (ginger).Chap. 2.6: The PulsesPulses are allowed:Medicago sativa (alfalfa, lucerne),Glycine maxima (soya),Cicer arietinum (chick peas),Phaseolus vulgaris (beans),Vicia faba (broad beans),Lens esculenta (lentils),Pisum sativum (peas),Fagopyrum esculentum (buckwheat or black wheat),Ceratonia siliqua (carob),Colutea arborescens (Erba vescicaria),Trigonella foenum graecum (fenugreek),Galega officinalis (galega),Lotus corniculatus (five-finger),Glycirrhiza glabra (sweet root),Lupinus albus (lupin),Melilotus officinalis (yellow melilot),Trifolium pratense, rubeus (clover),Anthyllis alpestris or vulneraria (kidney-vetch, lady’s-finger).GM pulses are dangerous (ALL 9 ESSENTIAL AMINO ACIDS :Valin, Isoleucin, Leucin, Lysin,Methionin, Arginin, Tryphtophan, Phenylalanine, Treonine Hystidine)NOT use of Glycine maxima (it’s GM);NOT use of Pisum sativum (GMO risk, 1011 );NOT use of Medicago sativa (GMO risk);NOT use of Phaseolus vulgaris (GMO risk)].62

Chap. 2.7.: Dried fruitDried fruit is forbidden to cancer patients because it contains a lot of ESSENTIAL AMINOACIDSCorylus avellana (hazelnuts)Olea europaea (olives); note: particularly rich in DHEA, useful against agingPinus pinea (pine nuts)Castanea sativa (sweet chestnuts)Juglans regia (walnuts)Arachis hypogaea (peanuts)Pistacia vera (pistachios);Prunus amygdalus (almonds);Note: be careful with seeds of bitter almonds (Prunus amygdalus), because they contain a lot ofvitamin B17. This makes 2-3 bitter seeds lethal for a child, and 12-15 lethal for an adult weighing70 kg. On the other side, they are extremely effective on cancer (SEE chapter 7).Chap.2.8.: breakfast, Lunch and dinnerChap.2.8.a: Useful breakfast in the morningThe human body starts to purify itself at about 4 in the morning, and completes this cycle shortlybefore 11 in the morning. During this extremely delicate stage, as it has to eliminate all the toxicsubstances that were absorbed in the previous 24 hours (food, air, water, skin contact), it must befed with great quantities of natural vitamins in order to help the detoxification of these poisons bycells, and the resulting expulsion of toxins from the body.The expulsion of toxins from the body (the quantity of expelled toxins) indicates how muchintoxication is in the body, and how much the body is able to discharge them.Urine should not smell of ammonia.Faeces should not have a bad smell, they should be soft, of bronze colour, and they should float inwater.Skin (the third discharging organ after urine and faeces) releases sweat in the morning, fromarmpits, from the groin and from feet, that should be washed at night and in the morning.In the morning the tongue is often covered by the classic whitish film of mucus.Thus, it is wrong to give the body too much proteic food, or food that is potentially rich in toxins:on the contrary, it is better to help it to purify from toxins that are not going to be eliminated before11 in the morning.Only at about 12 or 1 o’clock the body will be ready to be fed again with CARBOHYDRATES, theprimary source of calories (pasta, bread, legumes, potatoes) or even with PROTEINS (meat, fish,eggs, milk and dairy products)For this reason, in the morning one must eat fresh fruit, tea made with detoxifying grass, andvegetable juice: e.g., fruit juice, Chinese green tea (Camellia sinensis), Breuss juice, etc…Apple cider vinegar is interesting. People who have a delicate stomach should drink it with a glassof water (obviously chlorine-free and fluorine-free water). The apples it is made with must be ofexcellent quality and fermented in sessile oak barrels for at least six months.63

Chap. 2.8.b.: During the morningDuring the morning, on an empty stomach, it is a good habit to drink fresh vegetable or fruit juices,bought in “organic food shops” or in local public markets that only sell organic products, especiallyif it is not possible to make fresh fruit or vegetable shakes for work reasons.Chap. 2.8.c: When you cook vegetablesWhen you cook vegetables, you should not cook them for too long, because cooking them for toolong destroys the vitamins that are essential for the diet we are talking about. Thus, vegetables canbe steamed, cooked in the oven or tossed in a pan, but they should not be boiled in water, unless itis a soup (vitamins and mineral salts stay in the water).If you do not have fresh vegetables, frozen vegetables are preferable to vegetables in cans.Moreover, it is a good eating habit for the patient to drink fresh vegetable juices and fruit juices,together with the consumption of fruit and vegetable shakes.If vegetables are cooked, one should take the precaution of not cooking them too much, becauseexcessive cooking destroys the vitamin principles which are essential to the anti-neoplastic therapydescribed here: therefore, vegetables may be steamed, cooked in the oven or tossed in a pan, but notboiled in water, apart from soups (because the vitamins and minerals remain in the water).If fresh vegetables are not available, frozen ones are preferable to tinned ones.Chap.2.8.d.: Pickled vegetablesPickled vegetables are prohibited, because they are salty, and they contain cancerogenouscomponents due to the high concentration of nitrous elements which, once ingested, may formnitrosamines, which are strong cancerogenous substances.Chap.2.8.e.: Exotic fruitExotic fruit, or more in general fruit and vegetables coming from areas of the world with littlehygienic or health control, can be the means for infection by infectious diseases, sometimes insevere forms (cholera, salmonellosis, etc…) caused by dirty water (sewage) used to irrigate theground.Attention must be paid to fruit and vegetables which have been treated with chlorine, because itdestroys vitamin E and other active principles.Chap.2.8.f.: Drinking waterIt is best to take a litre of water from the tap and boil it for 20 minutes without a lid (in that wayallowing the chlorine to evaporate). Then it should be filtered through a gauze, eliminating all theresidues, and put in a thermos flask. Drink it hot during the day.64

Chap.2.8.g.: Lunch and/or dinner: The importance of cerealsIt is extremely important that cereals are wholemeal cereals.Of course, flour is the basic form to have them as pasta, bread, or polenta.Wheat is the most widespread cereal. Gluten is contained in its seeds in an ideal proportion, and itmakes it particularly suitable for rising and bread-making. There are two varieties of wheat: hardwheat (Triticum durum) and soft wheat (Triticum aestivum or vulgare). The percentage of aminoacids contained is about 13% (Triticum vulgare) and 12,5% (Triticum durum), but all 9 essentialamino acids are never present together. With the introduction of milling by steel wheels, that tookthe place of traditional grindstones, the large-scale production of white flour started. This flour isrefined, and has kept its energetic value, but not its nutritious value (vitamins), as it does not havethe outer layers of the grain (bran) nor the wheat germ (vitamin E).What happens is that very often companies try to add bran to white flour again, but the productobtained cannot be compared to true wholemeal flour: the true semolina has indeed a quite uniformamber colour, compared to these mixtures that are easy to recognize (characteristic inhomogeneouslook with brown parts that are darker or whiter).Other cereals: rice (amino acids: 6%), millet (amino acids: 11%), barley (amino acids: 11%), oat(amino acids: 12%), sweetcorn (amino acids: 9.5%), rye (amino acids: 16%), amaranth (aminoacids: 16%), emmer wheat (amino acids: 12%). The 9 ESSENTIAL AMINO ACIDS are NEVERpresent together.Common buckwheat (Fagopyrum esculentum) is not a cereal, but something different. It isparticularly rich in lysine (as LEGUMES) and tryptophan, and the amino acid percentage is about11%. It contains a lot of Iron, Magnesium and group B vitamins, vitamin B17 included. It must notbe eaten with cereals because ALL 9 ESSENTIAL AMINO ACIDS could be found together.Hippophae rhamnoides (Olivello spinoso) is rich of Lysine, as LEGUMES.Emmer wheat (Triticum spelta) does not have a high glycemic curve, contrary to other cereals, so itcan be used for people who need to avoid high glycemic peaks, such as for cancer or diabetespatients.Amaranth and rye are cereals. They have a high percentage of amino acids (16%), and they alsocontain lysine, an essential amino acid that is almost absent in other cereals. Therefore the risk is tosum up all 9 essential amino acids in case amaranth is eaten together with other cereals (e.g.: bread).Secale cereale (rye) and Amaranthus hypochondriacus (amaranth) are too rich in Lisin.Note: wholemeal pasta (emmer wheat, kamut, barley etc..), as it is wholemeal, releases starch, so,contrary to pasta made with hard wheat, it has to be carefully drained.The taste is stronger than the one of white pasta, to the point that, if you don’t want to lose thesubstances that you drain, you can keep them apart for an evening vegetable soup, for examplecooking some vegetables in bit of water with half bouillon cube, and mixing them with the drainedwater, until you get a cream. Many food substances are sold that try to integrate nutrition with alarge part of these cereals. You should choose wholemeal flour, without added substances.65

Chap.2.9.: FishPay attention to farmed fish because the feed comes from unsafe sources (for example - butcheredanimals): according to the author small-sized and salt-water fish should be chosen, possiblybelonging to species that tend to accumulate only small quantities of polluting substances (forexample: anchovies, needle-fish, skullcaps, pilchards, sardines, mackerel, etc...).Tuna, however, is considered to be a valid nutrient for neoplastic patients as well.Fish should be eaten only after the immunity cascade has begun, with a noticeable dimensionaldecrease in the tumour mass, given the possibility that the essential amino-acids found in fish couldbe assimilated by the tumour cells as well.Chap.2.10.: SugarsYou will notice the absolute exclusion of sugars, apart from fructose. This depends on the facts thatthe latter has a low glycemic index. Indeed, it works differently from other sugars (glucose,saccharose, mannose, etc..) as it is absorbed slowly by the intestine. From blood it passes directly tothe liver, where it is converted into hepatic glycogen.This avoids a dangerous hematic hyperglycemia, that, even though it can be transitory, can bedangerous for patients with cancer or diabetes.Chap.2.11.: SaltOrdinary table salt (sodium chloride) is the cause of ESSENTIAL HYPERTENSION in more than95% of cases. Only in 4-5% of cases it is due to diseases, usually kidney diseases.In private foreign “health” clinics, where the most common and frequent chronic-degenerativediseases are treated with mega-vitaminic therapies, it was shown that, even if salt is removed fromthe patients’ diet, they can continue eliminating 6 to 8 grams of sodium per day through the urinefor more than a week from the beginning of diet therapy before going back to a normal arterialpressure.Chap.2.12.: Toxic or dangerous food1) Sweetcorn (Zea mays): unfortunately it is a lost product, as it has a high transgenic pollution risk.Transgenic sweetcorn is dangerous both because of “Bacillus thuringiensis” (SEE below) and addedlysine ( 982 ) and/or tryptophane.2) Soya: it has a high trangenic risk, just like all of its byproducts, for example Tofu (soya“cheese”).3) Aspartame: induces cancer ( 1602 ). http://www.ehponline.org/docs/2007/10271/abstract.html4) Margarine : its SATURATED fatty acids block the action of vitamin F.5) Hydrogenated vegetable fats: they damage cell walls and hinder the action of vitamin F.6) GM salmon : it contains transgenic viruses (SEE chapter 8 about transgenic viruses).7) Peas: transgenic risk ( 1011, 2006 ).8) Beans : trasngenic risk.9) Peanuts (Arachis hypogaea): high amino acids content (26%) and very often geneticallymodified.10) Coconut (Cocos nucifera) and palm oil: they contain saturated fats.66

Chap.2.13.: Food that is dangerous for health if consumed often:Meat (it contains all 9 essential amino acids and vitamin B12),Ham, (it contains all 9 essential amino acids and vitamin B12),Eggs, (they contain all 9 essential amino acids and vitamin B12),Milk, (it contains all 9 essential amino acids and vitamin B12),Cheese, (it contains all 9 essential amino acids and vitamin B12)Liver (it contains all 9 essential amino acids and too much vitamin B12),Potatoes-GMO (if transgenic, they contain all 9 essential amino acids)Jam,Margarine,Pickles (nitrous compounds),Pollen of bee (it contains too many proteins and all 9 essential amino acids),BHA (E320),BHT (E231),Polyphosfates (E450),Ammonium chloride (E510),Acesulphane potassium (E950),Aspartame (E951),cyclamic acid (E952),Saccharine (E954),Hydrogenated vegetable fats,Yoghurt, (it contains all 9 essential amino acids and vitamin B12)Glycine maxima (soya) : it contains too many proteins and all 9 essential amino-acids,Tofu (soya "cheese"),Whey,Algae (some contain too many proteins and vitamin B12),Brewers' yeast (it contains too much folic acid),Muesli (glicemic curve),GM Salmon (transgenic virus),Raisins,Molasses,Sugar beets,Butter, (it contains all 9 essential aminoacids and vitamin B12)Lard,Tallow,Vitamin integrators (both synthetic and natural, if containing PABA, folic acid, vitamin B12),SAM (S-Adenosilmethionine),Carnitin (2 essential aminoacids: Lysin and Methionin),Green Barley of Hordeum volgare (Vitamin B12, folic acid, Lysin, Methionin)Arachis hypogaea (peanuts) for high protein content (26%) and transgenic risk,Coconut (Cocos nucifera)Palm oil (saturated fats),Tropical fruit such as Musa sapientum, acuminata, paradisiaca (bananas),Ananas sativus (pineapples), etc... (highly polluted by pesticides and deprived of many vitamins by the prematurepicking and the long period of travel).Chap.2.14.: The problem of breadBread baked with stone-milled, organic wholemeal cereals is good for health (vitamin F).Industrial bread with chemical yeasts must be eliminated from the diet, because it often containspork lard, and it seems that it is often enriched with North-American flour (transgenic danger).67

Chap.2.15.: The GMO dangerous (SEE also below in another pages)The foods which could, in the future, become extremely dangerous, even though they are notactually counter-indicated in the therapy described in this work are the following:- slow ripening and/or virus-resistant tomatoes;- slow ripening cauliflowers ( 968 )- slow ripening broccoli- slow ripening strawberries which are resistant to cold and frost- peas which are sweeter- rice enriched with vitamin A, and ALL the essential amino acids.- seven foreign grape varieties which have come from other high quality grapes: CabernetSauvignon, Shiraz, Chardonnay, Riesling, Sauvignon Blanc, Chenin Blanc e Muscat GordBlanco ( 737 )- seedless and/or virus-resistant melons- baby carrots- virus-resistant lettuces- insect-resistant rice- insect-resistant beans- The manipulation and irreversible genetic modification of the very important oil from theseeds of the Brassicaceae ( 806 ), which have anti-cancer properties.Note: the Zea maisIts stems provided a particular phtyto-therapeutic compound useful against various deficiency diseases. Now, becauseof genetic manipulation (GMO), the gene Bacillus thuringiensis, has been introduced, giving rise to grave concern forthe risks to the health of mankind deriving from this toxin.With regard to Bacillus thuringiensis different scientific studies have already shown its pathogenic effect in experimentswith animals and on the human cell line of normal lymphocytes.But there have been various studies, over a period of time, on Bacillus thuingiensis: in 1978 a French study (Rev.Can.Biol. 1978 June; 127-130) showed damage by Bacillus thuringiensis on kidney cells for doses of 0.1 mg of toxin permillimeter, and a little more for human diploid and heteroploid cells (about 1 mg of toxin per millimeter); it was notpossible to protect these cells from this toxin in any way.In 1998, subcutaneous injections of Bacillus thuringiensis in mice with a low immunocompetence, caused seriouspulmonary superinfections (J.Clin. Microbiol. 1998 July, 36(7): 2138-9), and the same French author repeated theexperiment using intranasal suspensions of the same spores of Bacillus thuringiensis with equal results on animals(FEMS Immun.;. Med. Microbiol. 1999 May; 24(1); 43-7).In 2000, it was shown that the toxin acted in a toxic way not only on diseased cells of the tumoral type (as happens,moreover, with many toxic substances, SEE Chemo-therapy) but also, unfortunately, the toxin Bacillus thuringiensisacted in a toxic way on normal human lymphocytes too, traditionally the human cells which are most sensitive topoisonous substances introduced into human organisms, and what is more, at doses inferior to those that are consideredtoxic for tumoral human cells (J. Appl. Micobiol. 2000 July, 89(1): 16-23).According to the author, all these studies could signify a direct depleting effect of Bacillus thuringiensis on thelymphocytic line, that is to say a serious indication of a possible anti-immunitary effect of Bacillus thuringiensis inman. This renders GMO foods, which are enriched with Bacillus thuringiensis, extremely dangerous, because theywould inhibit the anti-neoplastic immunitary response in patients treated with Phyto-therapy (Aloe, Essiac, the Gersondiet, the Breuss diet, Chinese and Indian medicine ....), and in reference to other diseases, Bacillus thuringiensis,because of its inhibiting action on the defense system could be capable of seriously worsening the condition of patientsaffected by Acquired Immune Deficiency Syndrome (AIDS); vice versa it could introduce immunitary imbalances inhealthy people causing allergies and food intolerances, or, unfortunately, induce auto-immune diseases, and probably,even tumors.Finally, seeing the effect on healthy lymphocytes, on intestinal and kidney cells, particular attention must also be paid tothe teratogenic risk to human foetuses and embryos in pregnant women.The toxin-producing gene of the bacteria Bacillus thurigiensis, for instance, is commonly engineered into crops toprovide them with a built-in insecticide. However, the toxin produced is known to resist degradation by binding itself tosmall soil particles whilst continuing its toxic activity. The long term impact of this toxin on soil organisms and soilfertility is unknown ( 1499 ).68

Chap.2.16.: Domestic pollutionMany toxic substances are nowadays being sold without any type of control: impoverished uranium(since 1999), sodium lauryl sulphate (SLS), propilenic glycol, diethanolamine (DEA), cocamideDEA, luramide DEA, Fluorides (sodium fluoride and hexafluorosilicic acid), Dioxin, Alum,Fluorocarbons, Formaldehyde, mineral oil and/or petroleum jelly, etc…“Impoverished” Uranium (and Plutonium) : SEE http://www.llrc.org/aldermastrept.pdf ;http://web.ead.anl.gov/uranium/uses/index.cfm ;http://www.newswithviews.com/Howenstine/james29.htm ),Below you will find some information about these toxic substances (taken from Phillip Day’s book:“Cancer: if you want life, prepare the truth”, Credence Publications)Dioxin: it is a cancerogenous byproduct of the procedure used to make foam in soaps like shampoo,toothpaste, and to bleach paper in paper factories. Plastic bottles treated with dioxin can transfer itto the food they contain. It is demonstrated that dioxin can cause cancer 500,000 times more thanDDT. ( 1207 ).Alum : Medicines containing alum must not be taken; when eating, cutlery containing aluminumshould not be used, because this substance de-activates various phyto-complexes, including vitaminE.NB: the danger of aluminum can be easily demonstrated by taking an aluminum bowl (or covered with tin foil inside),filling it with water and melting some sodium bicarbonate inside: when the aluminum comes into contact with analkaline substance such as the bicarbonate, it melts and forms a gas: it can therefore be presumed that aluminum causessome kind of poisoning, characterized by a gastro-intestinal inflammation because of the hydroxide in the aluminum,and possibly by a hepatic and renal degeneration.Fluorocarbons: they are gases or liquids that have no colour, they are not flammable, they cancause irritations in the upper and middle respiratory organs. They are usually contained in hairspray.Formaldehyde: it is a toxic gas, with no color, irritating and cancerogenous. It is used with water asa disinfectant or a preservative. It is found in many cosmetic products and common nail products.Mineral oil and/or petroleum jelly: they are used in baby oils. They derive from petroleum, that isnotoriously cancerogenous.Diethanolamine (DEA), Cocamide DEA, Luramide DEA : they are liquids without colour, orcrystalline alcohol, used as a solvent, emulsionant and cleanser (inhibiting agent). DEA works as anemollient in emollient lotions or as wettener in other personal care products. If it is present inproducts containing nitrates, a chemical reaction takes place and nitrosamines are produced, whichare potentially cancerogenous. Even though some previous studies seemed to show that DEA wasnot cancerogenous, more recent studies show that DEA does have the capability of provokingcancer, even in nitrate-free formulations ( 1208 ). DEA can also irritate the skin and mucousmembranes. Other types of ethanolamines that must be avoided are Triethanolamines (TEA) andMonoethanolamines (MEA).Fluorides (sodium fluoride and hexafluorosilicic acid): fluorides used in drinking water arenoxious, they are not biodegradable and they pollute the environment. They are officially classifiedas “contaminating” by the US Environmental Protection Agency. Such substances are industrialwaste, residuals of phosphate-based fertilizer production (Note by Dr. G. Nacci: the latter aresuspected to be responsible for the seaweed overproduction in the Adriatic sea during the summer)69

that are taken in by industrial pollution depurators and then sent to water pipes. Hexafluorosilicicacid, that is, the mostly used additive for fluorization, contains other noxious substances, includinglead, beryllium, mercury, cadmium, arsenic and radionuclides ( 1209 ). The noxious action of fluoridesis summed up in a clear statement by Dr. Dean Burk of the National Cancer Institute: “Fluoridecauses more deaths due to cancer and causes cancer quicker than any other chemical substance”.Fluoride is an electronegative element, it is extremely volatile, and it is never found isolated innature, and so it quickly combines itself to other elements. Fluorides were used as toxic gasesduring the First World War, and at the moment sodium fluoride is used as poison against mice.However it is also used in toothpaste for its alleged action against cavities.In October 1994, the medical journal “Journal of the American Medical Association” published aneditorial saying: “…the use of drinking water containing a minimum quantity of fluoride (1.2 to 3parts per million) could cause dysfunctions to bone development just like osteosclerosis, spondilosisand osteoporosis, and also goiter” ( 1210 ). In May 1992, Dr. William Marcus, the scientificconsultant in charge and toxicologic head of the US Environmental Protection Agency, was firedafter publishing his explicit statements about the scary risks linked to fluorides.Finally, in 1990-1991 fluoride was officially declared as a cause for cancer in animals and humans( 1211 ). Dr. Burk of N.C.I. said indeed: “We conclude that artificial fluorization seems to cause orinduce at least 20-30 more deaths for 100,000 people that were exposed to it for at least 15-20years…” (www.thewinds.org/archive/medical/fluoride01-98.htm ).However, it is incredible to think that today fluorization of water pipes and toothpaste is allowed,and furthermore the aim of the US government is to make it mandatory for water pipes in 75% ofAmerican cities in the next few years ( 1209 ).This is what medical scientific literature says ( 1212 ):1)Fluoride accumulates in the body just like lead, causing long-term damage2)Fluoride is more noxious than lead, and slightly less noxious than arsenic (Clinical Toxicology, 1984)3)Medical research shows that hip breaking occurs 20-40% more often in communities where fluorization is applied( 1212 ).On 8 December 1993 the American Medical Association (AMA) published an article called “Studylinks fluoride to rare bone cancer”. This study also showed that hip breaking occurred more often(27% more) in women and 41% more in men, in American cities with fluorization ( 1213-1219 ).70

Chap. 2.17.: the problem of the labels of food wrappingsFood must be of a good quality, possibly bought from organic food farms, or at least free of anydangerous chemical additives:Sulphuric anhydride (E220),Potassium nitrite (E249),Sodium nitrite (E250),Sodium nitrate (251),Potassium nitrate (252),Erythorbic acid (E315),Butyl hydroquinone (E319),BHA (E230),BHT (E231),Polyphosphates (E450),Monoglycerides and dyglycerides of fatty acids (E471),Esters of mono and dyglycerides of fatty acids (E472),Esters of saccharides of fatty acids (473),HC1 (E507),KC1 (E508),CaCl (E509),Ammonium chloride (E510),MgCl (E511),Acesulphane potassium (E950),Aspartame (E951),cyclamic acid (E952),Saccharine (E954),The “natural” aromatic herbs (synthetic, in actual fact), artificial aromatic herbs, flavour enhancers or added sugars.It is, therefore, important to properly understand and interpret the indications on the labels of foodwrappings.71

Chapter 2.18: Conventional agriculture (or chemical agriculture, orindustrial agriculture)The purpose of modern agriculture is the maximum yield for the farmer, regardless of the quality ofthe food obtained. He therefore has no qualms whatsoever about using chemical substances whichare completely extraneous to the plant's biological cycle, with devastating consequences for thebiological balance of the land which is subjected to these intense treatments.Substances such as pesticides or herbicides leave residues in the food, causing the growth oftumors. Only in Italy, in 1985 about 10 kg of pesticides per hectare were used...A partial list of pesticides which are known or suspected of inducing tumors in man are thefollowing ( 675 ) :Acephate (Orthene),acido arsenico,acido metilarsonico,Acifluorfen (Blazer),Alachlor (Lasso),Amitraz (Baam),Arseniato di Calcio,Arseniato di Piombo,Arseniato di Rame,Arseniato di Sodio,Arsenito di Sodio, (Asulam),Azinfos-metile (Guthion),Benomil (Benlate),Captafol (Difolatan), Captan,Cipermetrina (Ammo, Cymbush),Ciromazina (Larvadex),Clordimeform (Galecron),Clorobenzilato, Clortalonil (Bravo),Daminozide (Alar),Diallato,Diclofop-metile (Hoelon),Dicofol (Keltane),Ethalfluralin (Sonalan),Folpet, Fosetyl A (Ailette),Glifosato (Roundup o Rodeo),Idrazina maleica,Lindano, Linuron (Lorox),Mancozeb, Maneb,Methomyl (Dual),Metiltiofanato,Metiram,Metoalaclor (Dual),O-fenilfenol, Oryzalin (Surflan),Ossido di etilene,Oxadiazon (Ronstar),Paraquat (Gramoxone),Parathion, PCNB,Permetrin (Ambush, Pounce),Pronamide (Kerb),Terbutrin,Tetraclorvinfos,Thiodicarb (Larvin),Toxafene,Trifluralin (Treflan),Zineb.72

This production technique produces not only poisoned food, but also food which is lacking invitamin principles, co-enzymatic factors and essential minerals: it is not simply by chance thatnowadays even bakers need to enrich their flours, too poor in gluten, with North-American flours...(transgenic risk.…).Intensive cultivation, the forced selection of varieties which have been made use of precociouslyand excessively and the destruction of the biological system controlling insects and parasites(hedges, crop varieties, birds, predators) make it necessary to treat orchards with insecticides andanti-cryptogamic substances many times in the course of the year...The substances which are used nowadays are of a "systemic" kind: in other words, they are sprayedon the leaves and, through these, they are absorbed and carried with the lymph, impregnating thewhole plant, including the fruit.Therefore, there is no point in trying to modify the pollution of fruit by simply washing it under tapwater (often containing chlorine).In this way, perhaps, it is possible to eliminate the substances with which the fruits are polished, thepurpose of which is to slow down the gas exchanges between the fruit and the environment afterpicking, thus preventing the ripening process taking place too rapidly, with a consequent precociousshriveling of the fruit. But the really resolute choice is to eat fruit which has been cultivated withbiological systems, or deriving from integrated productions.In Europe, the best countries for this new kind of agriculture are Holland and Spain.73

Chapter 2.19 : Organic farming and small-scale retail tradeOrganic farming is a complex system, based on the conservation of the soil's fertility, the use oftechniques with a low impact on the environment, the conservation of genetic, agronomic and, asfar as possible, natural diversity.In organic farming chemical substances such as fertilizers, herbicides, anti-cryptogamic substances,insecticides or pesticides are never used.The crops are defended, first and foremost, in a preventive way, selecting species which showhardiness towards illnesses, and intervening with appropriate cultivation techniques (the rotation ofcrops, the planting of hedges and trees able to give shelter to natural predators and to serve as aphysical barrier against possible external polluting agents and the mixing of different crops andseedlings, etc...).Fertilizers are strictly of natural origin, for example manure, appropriately composted, the use ofmown grasses and green manure, that is, the incorporation into the soil of plants, such as clover andcharlock, which have been previously planted and picked.Another interesting aspect is the use of plants (exotic ones as well) which possess anti-parasite oreven insecticide qualities such as Acorus calamus, Tribulus terrestris, Azadirachta indica and manymore (NB: a list of Asian, African, Australian and American plants appropriate for such purposes isbeing analyzed).When necessary, intervention for the defense of the crops is done with natural substances ofvegetable origin, particular animals (predators), or minerals which are expressly allowed and/orauthorized by the E.E.C.(E.E.C.=Comunità Economica Europea) Regulations, such as, for example,extracts of Azadirachta indica predator insects, pulverized rock, copper, sulphur, in this wayobtaining the correction of the vital bio-chemical components present in the soil, or even its defenseagainst cryptogams and other infestations.The common definition of "Organic Product" is not correct: the E.E.C. Regulation No. 2092 of1991, and over thirty modifications and integrations that followed, establish that what is "organic"is not the product, but the agricultural method used for its production. Therefore, there is no"organic" apple or "organic" fruit juice, but an apple from "organic farming" or a fruit juice from"organic farming"."Organic farming" products cannot contain Genetically Modified Organisms (GMO), nor can theyhave been subjected to sterilizing treatments with radiation.If additives are necessary, they must be chosen from the ones that the E.E.C. Regulation expresslyauthorizes (some raising agents, some acidity correctors, some emulsifiers, but no coloring agents,preservatives or flavor enhancers). At least 70% of ingredients must be of organic produce; theremaining ones must be among the those that are expressly authorized by the E.E.C. Regulation(algae, sugar beet, rice starch, cola nuts, etc....) and reference to the biological method is allowedonly in the list of ingredients.Only if at least 95% of the ingredients derive from organic farming is the reference to the biologicalmethod allowed in the selling name (organic farming apricot jam, organic farming pasta, etc...). Inthis case as well the possible components which are not of biological origin will have to be includedwith those that the Regulation authorizes, but it will not be necessary to indicate in detail thebiological origin in the list of the ingredients.Before its products may be considered biological, a farm must undergo a period of "changeover",during which the land will be detoxified from the treatments of chemical agriculture (conventionalagriculture) to which it was previously subjected; the length of time of the changeover isdetermined for each single case by the controlling authority. To be put on the market as "inconversion", a product must have been cultivated in the full respect of all provisions for a period oftime no shorter than 12 months before planting.74

Author's considerations of Organic FarmingThe "changeover" of the land is certainly the most critical aspect for the setting up of real "OrganicFarming" in Italy.In countries like Holland, the land is prepared on the basis of the following parameters:1) land is chosen from those that have just been taken away from the sea for the building ofnew dams.2) intensive changeover cultivation is followed for at least 3 years using particular plants, thepurpose of which is to eliminate salt and other substances present on the seabed.3) greenhouses and pure water with purified external air are used.4) the State controls the quality of the land only after at least 3 years of "changeover".Therefore, to start organic farming in Italy, where farmers have carried on poisoning the land for atleast 50 years with pesticides, herbicides, anti-cryptogamic and other toxic substances, is going tobe extremely difficult.The author has therefore proceeded to initiate a series of studies for the chemical and radioactivedecontamination of the land, with the intention of elaborating a proposal on this subject: in fact,there are about 1,500 chemical products which are variously used (in particular the active principlesof pesticides); the many chemical polluting factors present in the river waters that are used for theirrigation of the land, and even rainwater, are a cause of environmental pollution.Phyto-decontamination:According to the author, what could therefore be done is to institute some Organic FarmingConsortiums and situate them in the lands which have been decontaminated with the appropriateplants such as Arundo donax, Heliantus annuus, the latter being particularly effective even againstradionuclides like Caesium 137 and Strontium 90 in Chernobyl ( 676, 677 ) Zea mays, Fagopyrumesculentum, Iris pseudo-acorus, Typha latifolia, etc...(Perhaps, against the Uranium in exYugoslavia..)Thus, the return to a capillary distribution of fruit and vegetable products, based on the trust existingbetween producers of fruit and vegetables, the owners of shops, both big and small, includingsupermarket chains, and regular customers, would be the best guarantee with regards to “organic”products, irrespective of the more or less valid certifications of the "organic" product's goodness.This could reopen the market to a positive and conscious competition between big and smallEuropean companies interested in revaluing agricultural lands which are still being subjected tooverexploitation in the cultivation techniques used; these can no longer be considered "modern" in ascientific sense, on the basis of current knowledge in human biochemistry (cancer causing) and inthe environmental biology of flora and fauna.For the Renaissance of organic agriculture in EuropaThus, it is necessary to keep the seeds of the short but great worldwide agricultural tradition, bornfrom agricultural traditions, the result of ages of traditions in peasant civilization. But, if thecountryside is less and less populated, if little family-run agricultural companies give up to fewhuge companies that cultivate GM products, if the only market solution is that of the greatorganized distribution, then there is no hope for the biodiversity of organic agriculture, the directdescendant of thousands of agricultural human civilizations, because the great distribution of foodproducts itself has been the main cause of its disappearance.In order for biodiversity to come back, in order for the old varieties of fruit, vegetables, cereals and75

legumes to be cultivated again, it is necessary to create the bases for a Renaissance of theworldwide peasant culture, that was born from the work and the fusion of millenary world cultures.This new base will give a huge economic help to organic agriculture by selling directly (withoutintermediaries) farm products, coming directly from the hands of the farmer to the hands of thepatients and their families.Small covered markets will have to be built, where the LAW can check whether the prices fororganic products are fair. The prices will then be decided respecting the prices of similar productssold in nearby places, thus avoiding speculation, and sold above a certain price, in order to helpfarmers continuing their organic production, because this will mean respecting a “fair price” for thefarmer.This model represents the close future; it is the present for many companies in Europe, and it causesa series of positive effects on the economy of the countryside.It is thus important to connect peasants to people living in cities, using free lists of organic foodcompanies, that are able to sell their products directly (INTERNET), that is “local food”, or a “mapof local food”.Christmas 2005: Crisis of the organic market in the USA(Extracted from Just Food, 20 th December 2005)According to Organic Monitor, most sectors in Organic Farming are facing a lack of rawproducts, which is hindering the market development: a shortage of biological products isleading American companies to search for raw material abroad. The amounts of importedFRUIT, VEGETABLES, CEREALS, LEGUMES and OFFICINAL HERBS are increasing.In the international trade, American importations are increasing steadily: importations in theUSA are estimated to be over 1-2 billion Euro-dollar, as against 100-200,000 Euro-Dollar ofexportations of American products.The shortage of organic products is causing economic problems: almost all sectors in OrganicAgriculture are in crisis. Many American retailers had empty shelves during the year. Forexample, on the market of organic FRUIT juices, one of leading company is going out of themarket because there is a lack of organic FRUIT in the USA and importations from abroadhave prohibitive costs.Organic Monitor estimates that 80% of actual production of organic juice will disappear fromthe American market because of the withdrawal of this USA company.76

Chapter 2.20The latest deception: Marker Assisted Selection (MAS).When genetic deception returns to farmers’ fields through HYBRIDplantsLarge biotechnology (i.e. GMO) firms such as Monsanto, Syngenta, Bayer, Pioneer, etc. argued foryears that GMOs represented a scientific and technical revolution in agriculture and that thisrevolution was the only efficient and economical way to feed a growing population in a smaller andsmaller world. Independent scientists and other authoritative figures have often presented factualdata showing that these statements are completely unfounded.Recently, the above-mentioned multinationals have been using another form of deception which isknown as Marker Assisted Selection (MAS). It is a complex method used to significantly acceleratetraditional selection processes without modifying them genetically as in the case of GMO seeds. Sofar there is no harm. In this way, it is possible to select plant varieties with better characteristics fora particular environment.In the Netherlands, the new technique allowed to develop a new variety of Lettuce which isresistant to a particular aphid and, in India, one of Millet resistant to drought and mildew.Furthermore, Syngenta created a NON-GMO variety of wheat which is more resistant to fusariumfungus.This form of “assisted selection”, which was developed in the large laboratories of those biotechfirms and aims at putting the so-called “Marker Assisted Selection” on the world market as analternative to GMOs, hides however a great deception: the plants produced are all “HYBRID”, i.e.sterile.They can produce higher yields compared to natural plants but farmers cannot sow them again intheir field.Besides, before the recent advent of GMOs on the market, “hybrid” plants had become more andmore diffused for some decades.The following is a brief analysis of what happened, drawn from Laura Silici’s “OGM: Le veritàsconosciute di una strategia di conquista” (“GMO: The hidden truth of a strategy of conquest”),Editori Riuniti, via Alberico II, 22 – 00193, Rome.That hybrid varieties are also a source of wealth for the “Seed Industry” does not surprise. Theseplants differ from normal ones not because they produce more – as advertised for decades – butbecause they reduce the yields of the next generation.The expression “hybrid varieties” hides therefore a double deception: first of all, they are not“varieties”, and secondly, being “hybrid” is not a peculiar characteristic of them. The selector usesthe selection-cloning method: the result is not a hybrid variety but a number of clones, and thevariety is substituted with the best clones.On the basis of Mendel’s laws, discovered in 1900, the American biologist George Shull noted thatit is possible to clone maize “haphazardly”, i.e. using the isolation mechanism. In his first majorpaper, Shull explained the cloning-selection principle without revealing its method. He stated thathe had solved the main problem of the selector, namely “having the original pedigree”. In his77

second major paper, “Il metodo delle linee pure nella selezione del mais” (January 1909), Shullexplained his invention. The title suggests that he actually settled the issue of maize cloning.On the basis of Mendel’s segregation, he proposed to apply successive self-fertilizations to multiplya “pure line” (homozygote) which – like autogamous plants – keeps its individual characteristics,provided that it is cultivated separately. Pure lines are significantly weakened by self-fertilizationand so they cannot be used directly by farmers. Only after crossing pure lines two by two, the sorterproduces normal plants which have recovered their vigour. Then, as many copies as needed can beobtained from these plants through cloning, given that their parents are known. At this point there isnothing left to do but isolate the best clone.However, this method has an insurmountable practical difficulty: it is blind. Self-fertilizationsproduce a really great amount of lines and an even greater amount of clones. Since the lines arevery weakened but can produce excellent clones anyway, the selection can only take place amongthese. Why clone maize, then?Because the sorter is obviously interested in a plant which does not keep its original features from ageneration to another: in the field the clone loses the characteristics which brought farmers to sowit. In other words, maize undergoes a process which was studied by Darwin in 1876, known asconsanguineous depression. The closer the relationship between crossed individuals, the more thismechanism affects the variety produced by cross fertilization. In this way the selector forcesfarmers to sow clones – genetically identical plants – and induces them to transform their fields intoself-fertilization machines (in the laboratory, the self-fertilization process consists in associatingmale flowers with female flowers and in carrying the mature pollen from the former to the latter.Self-fertilization is the most extreme form of consanguinity: the following generation is socompromised by consanguineous depression that harvested wheat cannot actually be sown. Thenthis dispossession had to be disguised as an improvement. Genetics and geneticists made everyeffort to attain that objective for more than a century.The isolation technique needs cloned plants, which are simply hybrids of whatever plant of maize.It can be said that hybridism – common to all plants of maize – is the distinguishing feature of theclone substituting the variety. The misrepresentation of facts consists in arguing endlessly about thegenetic mysteries of hybridism as if they were linked to the cloning-selection technique. It was evensaid that “…knowing the genetic processes of heterosis was not essential for improving maize”(Coors, Cymmit, 1997).Thus, on the one hand the selector uses self-fertilization to sterilize maize, on the other hand thegeneticists believe and make people believe that they are using its hybridism – the contrary ofconsanguineous depression – in order to improve it. In their own words: “the contrary of theconsanguineous depression is known as hybrid vigour or heterosis” (Falconer, 1981, page 230).For more than a century, geneticists have been trying – naturally without success – to explain themysteries of hybridism, as on the occasion of the Cymmit symposium (International Center forWheat and Maize Improvement) which took place in Mexico City in 1997, sponsored by thegenetic-industrial complex (Monsanto, Novartis, Pioneer, Asgrow, Dekalb, Cargill, Plant GeneticsSystem) and its political supporters (The World Bank, USA Department of Agriculture, USAID andRockefeller Foundation).Fifteen kilograms of clone seeds – an amount necessary for a hectare of land – cost about 150 eurosin France, i.e. the same price as 16 or 18 quintals of maize seeds. A quintal of hybrid seeds costsabout 1,000 euros, that is 100 times more than the price of the maize grains which would be used asseeds the following year, if only farmers could sow them.That is the revolution of maize “hybrid” varieties and the aim of scientific debates: distortingdispossession and then explaining it as an improvement. Genetics acts again as an ideology ratherthan a science. (Richard Lewontin: “The doctrine of DNA, Biology as ideology, Penguin Books”).Nowadays, clones are five times more productive than varieties cultivated during the years after theSecond World War. To understand what is happening, it is enough to follow the logic of thecloning-selection technology without thinking in terms of hybrids and hybridization. The78

misrepresentation consists in attributing the improvement not to selection but to hybrids. First of all,selectors isolate some clones – obviously better than those of unselected varieties – and thenattribute the success of the selection process to hybridism.Back in 1910, E. Funk proved that it was possible to improve wheat through selection. This wasconfirmed by recent results: “…as a matter of fact, several properly conducted long-term studiesfor the improvement of cereals produced genetic benefits which were greater or equal to theaverage of 60 kg wheat per acre and per year registered with hybrid seeds” (Coors, Cymmit, 1997,page 170).The following is a summary of the main characteristics of the misrepresentation of facts:1) Dispossession of living beings: hybridization is a dispossession.2) Misrepresentation of scientific facts: science and some scientists, in particular genetics and somegeneticists, have an ideological function, i.e. passing the dispossession off as an improvement.Backward scientific knowledge compared to current advanced technology (genetics really took itsfirst steps in 1914, when Shull postulated hybridism properties using the concept of “heterosis”)allows to legitimate a genetic theory whose credibility is due only to the economic power of itsinventors.3) Self-celebration of hybridism properties: in the name of this genetic theory (with the benefits ofhybridism or “heterosis”), in February 1992 the US Secretary for Agriculture, Henry CantwellWallace, decided that hybridization would be the only method used to improve maize. He took thisdecision on the advice of his son, Henry Agard Wallace, who selected and produced maize seeds,would become Secretary for Agriculture during Roosevelt’s administration in 1933 and wouldfound Pioneer in 1926 – the largest cement multinational today. Wallace was impressed by the newgenetic science and by its prospects in the field of manipulation of living beings. In 1946 hecompared the power of heterosis to that of the atomic bomb. Conventional selectors which haddoubts about the properties of hybrids were ignored and replaced with hybrid corn breeders, alldirect or indirect followers of East and initiated into the scientific esotericism of hybridism.Varieties traditionally cultivated by farmers were abandoned in their genetic state around 1910.About fifteen years had to pass for genetic theory to be accepted. Around 1935, captif clones provedto be normally better than “free” varieties.Please note: Pioneer, founded in 1926 with a capital of $7,600, was bought by the chemist DuPontfor about 10 billion dollars in 1999. The worth of each invested dollar increased by 1,500,000 timesover 73 years. The capital of the selector multiplies only if plants are not allowed to multiply in thefarmer’s field.4) The socialization of dispossession costs: in 1992 the US government launched a researchprogramme with generous support and close coordination. It was an innovation in the field ofagronomic research, which up to that moment had been neglected. In 1936, about one hundredpublic breeders conducted scientific studies (Jenkins, 1936) and some individual selectors carefullyfollowed their results.5) The inexplicable theory of heterosis: thanks to the success of hybrid varieties, the deceit wascomplete and the misrepresentation worked properly. The “lysenkist” followers succeeded inimposing “hybrid varieties”. Rightly so: the government had defended the public interest. Soheterosis came to mean millions of tons maize more. How could it happen? As far as the “breeders”are concerned, their task was to make this dispossession technique triumph and not to challenge thedecision. Through selection they succeeded in improving maize in spite of – and not because of –the choice of hybridization. Certainly, they would not dispute the initial decision after achieving thesuccess.79

6) Impotent awareness of victims: American farmers were the only ones who suspectedmanipulation of facts: they were the victims of this. They called the revolutionary maize “mulemaize”. As a matter of fact, the mule is known to be sterile. But public breeders had made this“mule maize” better than conventional varieties, so that there was nothing left to do but buy theirseeds every year.From: “OGM: le verità sconosciute di una strategia di conquista” (GMO: The hidden truth of a strategy of conquest),Laura Silici, Editori Riuniti, via Alberico II, 22 – 00193, Rome.Chap.2.21.: From hybrid plants to GMO TERMINATOR plantsToday, hybrid plants have been surpassed by biotechnology applied to GMOs: completely sterileplants, i.e. unable to reproduce, have been created. In October 2005, this kind of biotechnology,known as “TERMINATOR”, obtained its first patent in Canada. This fact poses a grave threatbecause of the possible negative effects on diet. This issue will be discussed at the sixth point of thenext paragraph : “The threat of Genetically Modified “.Chap.2.22.: The Threat of Genetically Modified OrganismsCancer is a degenerative disease caused by a lack of vitamins and poisoning from chemicalsubstances present in food. One can estimate the number of vitamins and pro-vitamin substancespresent in natural plants commonly used as food by humans, as more than 13,000 – 15,000 types.The introduction into modern agriculture of Genetically Modified Organisms (GMOs) is anunjustified and dangerous alteration of what Evolution has produced in plants over hundreds ofmillions of years: plants on which the subsequent biochemical evolution of superior complexanimal organisms has been based, culminating with the advent of mammals in the last 65 millionyears and then with the arrival of Man. Therefore the delicate biochemical balance of the humanrace depends on plant species remaining integral, just as evolution created them, because the healthof every one of us is based on the biochemical human cell, and this depends, through thecomplexity of the DNA, on the use of thousands of vitamins and of the herbal-chemical compoundspresent in nature.GMOsTo get maximum agricultural production today we resort to changing the genetic patrimony ofnatural plants, with the aim of changing their structure and making them sterile (thus farmers haveto buy new seeds every year), patenting the transformation induced and re-selling the product allover the world. Furthermore it can be affirmed that there is a substantial equivalence between thegenetically modified product (GMO) and that obtained by selecting genetic characteristics (that isby means of naturally crossbreeding plants as has been done by man over the course of thousands ofyears). This eighth declaration says however that this ‘substantial equivalence’, cannot be sustained,because the natural crossbreeding of plants uses natural seeds of the same species, while geneticmanipulation (GMO) crosses all barriers, and introduces genes from other types of vegetablespecies or even bacteria, viruses and animal genes. In fact the majority of genes used in genetic80

engineering come from living species which have never been a part of the human food chain andactually come from DNA not of plants but of animals, bacteria or viruses and/or transgenicretroviruses.As a doctor qualified in nuclear medicine the author has had the opportunity to study the effects ofionizing radiation on complex organisms for years. It is his personal view that plants, too, arecomplex organisms, they are the fruit of hundreds of millions of years of biological evolution:every genetic modification caused in plants by man (with radiation such as Chernobyl, or withviruses such as presently used in GMO), however small that modification is, will cause damage,irreparable damage which often cannot be seen, because man only knows a limited number of safevitamins and pro-vitamin substances. However, there are tens of thousands of vitamins and othersubstances present in plants, and it is these which are responsible for the correct working of thebiochemical human complex and the human genome (DNA).8 immediate threats can therefore be identified.FIRST POINT: The impoverishment of vitamin and pro-vitamin complexes in the plantsThe impoverishment of vitamin and pro-vitamin complexes no longer present in food, with theconsequent increase in degenerative and deficient diseases such as Cancer (see the seventh and theninth declarations). The deliberate attempt to deactivate the natural substances contained in theplants is very serious: in this way fresh fruit and vegetables – greatly impoverished of manyvitamins – can be carried over long distances and long periods of time because their oxidation doesnot take place. These vitamins are able to enter into complex enzymatic mechanisms of DNAmammals, inducing the apoptosis (suicide) phenomenon in these mammal cells if diseased throughinfection or other illnesses (such as cancer). This vitamin impoverishment will ensure commercialprofits and represents a serious act of deliberate damage inflicted on the Ecosystem by means ofGMOs.It’s heavy the possible disappearance of anti-cancer vitamins, that induce apoptosis (suicide) of thetumors (Anthocyanin, Flavonoids ( 1122 ), Polyphenols ( 1123 ), sesquiterpene lactone Parthenolide ( 701 ), penta-acetylGeniposide ( 1061 ), Camelliin B ( 698 ), beta-Cryptoxantin ( 1063 ), Hesperidin ( 1063 ), Emodin ( 247,333,715 ), ursolic acid ( 700 ),allyl Sulfur ( 694,696 ), Eriodictoyol ( 693 ), hibiscus protocatechin acid ( 692 ), Indoles ( 809 ), Isothiocyanates ( 809 ), Resverarol( 695 ), Elemene ( 690 ), Acutiaporberine ( 711 ), Capsaicin ( 719 ), Wagonin ( 713 ), Fisetin ( 713 ), carnosic acid ( 1062 ), Germaniumsesquioxide ( 269 ), epigallocatechin Gallate ( 173,1124 ), Axerophthol palmitate, alpha and beta Carotene, trans-Retinoic acid,Tocopherols, Limonene ( 693 ), Cynaropicrin, Lycopene ( 633,1359 ), Proanthocyanidin, Damnacanthal ( 1043 ), Baicalin ( 718 ),Baicalein ( 718 ), hydrocinnamic acid ( 693 ), sesquiterpenoids as Atractylon ( 704 ), as Atractylenolides I, II, III ( 704 ),gelsemium alkaloids ( 699 ), tartary buckwheat flavonoid ( 1064 ), Sinigrin, ferulic acid, ellagic acid, cumarinic acid, …)SEE: http://www.erbeofficinali/dati/nacci/allpdf.phpThe disappearance of these natural anti-cancer vitamins is a grave threat.In Chapter 5 (“Plants which make Cancers suicide”) many vitamins and plants which induceapoptosis (cancer suicide) are listed. Moreover, scientific references about modifications made byGMO Multinationals are reported. This disappearance may happen also because of accidental GMOmodifications of plants: for example, Pueraria species is rich in Anthocyanins, i.e. a substancesable to induce tumour apoptosis. But in case of GMO Pueraria (accidentally genetically modified),its content of Anthocyanins is dramatically decreased by 40%.SEE PDF allegated: Joung JY.: An overexpression of chalcone reductase of Pueraria montana var. lobata altersbiosynthesis of anthocyanin and 5’-deoxyflavonoids in transgenic tobacco, Biochem Biophys Res. Commun 2003, 303,pp.: 326-331 http://www.mednat.org/alimentazione/PUERARIA.pdf)The 2005 study by Woitsch and Romer ( 1740 ) also reveals that GMO plants lose their capacities toproduce vitamins, although they wew created in the laboratory for that purpose, if put out oflaboratories, i.e. in the real environmental conditions of climate stress (temperature change betweenday and night, wind, sun’s ultraviolet rays, etc….). This is essentially due to the complete ignorance81

of Science about the complex biochemical repair mechanisms that plants must activate in conditionsof environmental stress of different origin, differently from natural plants, which have evolved forabout 500 millions years and are naturally and spontaneously able to produce a number of vitamins– most of which still unknown – in order to protect themselves from the environmental stresscaused by ultraviolet rays, the temperature range between day and night, viral, bacterial, fungalinfections, etc…. (http://www.mednat.org/alimentazione/Nacci_Vitamins_in_GMO_Plants.pdf )In addition to the possible disappearance of anti-cancer vitamins that induce apoptosis (suicide) oftumors there is the elimination of seeds from GMO fruits. The importance of seeds as anti-cancerfactors resides principally in the fact that they contain vitamin B17.But it is extremely serious that the big GMO seed Companies are putting onto the world agriculturalmarket the same fruits but without seeds, in particolare: Cucumis melo, Citrus limonum, Citrullusvulgaris, Solanum lycopersicum, Vitis vinifera.The deliberate attempt on the part of companies producing GMO to deactivate this precious naturalmechanism contained in plants is very serious. This is a deliberate act of damage inflicted on theecosystem by Agro-industrial Multinationals GMO.SECOND POINT: genetic mutation of plants and the subsequent alteration of humanbiochemistryBecause of the introduction of foreign genes (for example from animals, bacteria, viruses andretroviruses) into the DNA of plants, an alteration in the normal genomic sequence of the plantoccurs, with the appearance of new proteins and/or the loss of other proteins of a genomic sequence.Therefore new substances similar to natural vitamins have appeared, but which actually haveenzymatic and biochemical characteristics different to natural ones, and therefore introduce changesin their component of biochemical activity on the human genome, once they have been introducedthrough food.There is therefore the potential risk of new diseases of an “artificial” type, caused by the geneticmanipulation (GMO) of vegetable organisms, genetically polluted by new vitamin-like moleculeswith inductive effects on the human DNA and on its complex biochemistry which are totallyunknown, but probably heralding serious damage given the extreme complexity and hencevulnerability of the human DNA.For example, the only test on a long-term basis (24 months) carried out by an Italian research groupdemonstrated that GMOs may modify some internal organs. Feeding mice with the famous maizeRoundup Ready changed the structure and the functioning of their liver, pancreas and testicles cells.(Malatesta M.: Fine structural analyses of pancreatic acinar cell nuclei from mice fed on GMsoybean. Eur. J. Histochem., 47: 385-388, 2003; http://www.mednat.org/alimentazione/Malatesta.pdf) ( 1579-83 ),A second study was conducted by Pusztai: he found out that mice fed with transgenic potatoesshowed damage to organs, thickening of the small intestine and scarce brain development. Potatoeswere genetically modified in order to contain lectin, which makes plants resistant to pesticides.(Pusztai: Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat smallintestine, The Lancet Vol. 354, October 16, 1999) (http://www.mednat.org/alimentazione/Pusztai.pdf),SEE: Pusztai ( 1578, 1588 ) (http://www.gmwatch.org/p1temp.asp?pid=66&page=1);A third study was carried out by Prescott, who analysed GMO peas (Prescott: Transgenic expression ofbean-amylase inhibitor in peas results in altered structure and immunogenicity, J. Agric. Food Chem., 53, (23), pages:9023-9030, 2005. http://www.mednat.org/alimentazione/Prescott.pdf.82

A fourth study was conducted by a team led by Dr. Irina Ermakova in Russia, a biologist of theInstitute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences(RAS) in Moscow.This study carried out by the Russian Research Agency suggests that a diet based on geneticallymodified food can cause damage to progeny. It was presented by the National Association forGenetic Security (NAGS) at a symposium on genetic modifications, which was organized by theAmerican Academy of Environmental Medicine and took place on 10 th October 2005. During thetests, the Russian scientist added GMO soya to the food given to female rats two weeks before theconception and during the feeding. In the control group, female rats did not receive any GMO.There were three groups with each a different diet: the control group did not receive soya, thesecond one received GMO soya and the third one received conventional soya, i.e. NOT GMO.Scientists counted births and deaths of the animals undergoing this test. Three weeks after the birth,dead animals were counted. The following was observed: conventional and GMO soya do notinfluence the number of rats born of each mother. However, the number of dead animals wasradically different after three weeks. The results showed that conventional soya, i.e. NOT GMO,does not influence the death percentage negatively, whereas GMO soya makes it increase in a ratioof one to 8 births. Furthermore, 30% of the newborn mice in the group fed with GMO soya weighed20 grams less than normal. These results are particularly worrying as rats’ morphology andbiochemical structure are very similar to human beings’ oneshttp://eco-irina-ermakova.narod.ru/eng/index.htmErmakova ( 1584 ), Food Standards Agency News ( 1585 ).A fifth study, which was commissioned by the Austrian Ministry for Agriculture and Health andcarried out by Dr Jurgen Zentek, professor of Veterinary Medicine at Vienna University and leaderof the project, demonstrated that mice fed with GMO corn gave birth to a reduced litter already atthe third or the fourth generations, differently from the mice fed with normal corn.THIRD POINT: the failure of an anti-cancer dietAs has already been demonstrated by Gerson ( 749,750,969 ) and other authors, many substancescontained only in fruit and biologically grown raw vegetables are able to induce the immunecascade against tumors, detoxification and the particular phenomenon of apoptosis (suicide) ofdiseased cells making it unnecessary to do difficult and expensive research. Let us take the case of153 patients suffering from the worst form of cancer known (Melanoma), who followed the anticancerdiet of Dr. Gerson ( 749,750,969 ) : after 5 years the percentage of recovery varied from 70-90%(if the tumor was localized) to 40-70% (if the tumor had metastasized), provided the patients hadnot previously undergone chemotherapy. On the contrary, with chemotherapy the percentage ofrecovery from Melanoma cancer after 5 years is 6% ( 969 ) or zero ( 1340 ).Note: in the latter source ( 1340 http://www.mednat.org/cancro/MORGAN.PDF ), based on about 250,000 Americanand Australian patients, this zero survival value is confirmed even in the case of pancreas cancer, sarcoma, wombcancer, prostate cancer, bladder cancer, kidney cancer and multiple myeloma, going up to 1% in case of stomach andcolon cancer, about 2% in case of breast or lung cancer, 3-5% in case of rectum cancer, 4-5% in case of brain cancer,5% in case of esophagus cancer, 9% in case of ovary cancer, 10% in case of NON-Hodgkin lymphoma, 12% in case ofcervical cancer, about 40% in case of testicular cancer and Hodgkin lymphoma… ( 1340 )The explanation of the effectiveness of these vegetarian diets lies in the fact that patients do notconsume food containing all the potential factors which promote cell growth, in particular they donot simultaneously consume the 9 essential amino acids (Valin, Isoleucin, Leucin, Lisin, Metionin,Hystidine, Tryphtophan, Phenylalanine, Treonine), nucleic acids (DNA, RNA), vitamin B12, folicacid and also para-aminobenzoic acid [PABA].Once the foods which contained all of these were of83

animal origin (meat, fish, eggs, milk, cheese, butter…): both Gerson and other authors (includingChinese and Indian medicine) forbade the consumption of these foods for at least a year. Avegetarian diet, based on fruit and vegetables, cereals and pulses, was, thus, the winning diet. Thesefoods are rich in protein and thus their use in cancer therapy by Gerson and other Western, Chineseand Indian schools of natural medicine might seem surprising. But the reason for their use is that nocereal and no vegetable contained by itself the 9 essential amino acids. These foods, however, ifconsumed together at the same meal determined the assimilation of the 9 amino acids. Therefore itis absolutely forbidden to eat together pasta (or polenta, or bread [even if unleavened] or rice),withpulses, because there would be the integration of the 9 essential amino acids (8 contained in cereals+ 8 contained in pulses) with a similar nutritional effect as that obtained from meat (after all once aplate of pasta and beans was called … “poor man’s meat”).Today, however, because of the introduction on the market of cereals, legumes and other vegetableswhich have been genetically modified (GMO), many of these foods contain ALL the essentialamino acids ( 1065 Day P.R.: Genetic modification of plants: significant issues and hurdles success,Am.J.Clin.Nutr., 63(4), pp.: 651S-656S, 1996http://www.mednat.org/alimentazione/DAY.pdf), effectively rendering cancer NO LONGERcurable in the way it is described in this study and according to the therapy of Gerson ( 749,750,969 )and many other authors.FOURTH POINT: diseases induced by transgenic virusesThe transgenic viruses with which genetically modified organisms (GMO) arecreated today enter into the DNA of the plant, modifying it in a way which isunknown to us.These viruses are supposed to lie dormant but there is nothing to prevent them fromreactivating themselves in a manner similar to the well known RNA tumour viruses(Oncornaviruses) or DNA tumour viruses (both inducers of leukaemias, sarcomas,carcinomas, gliomas...).These viruses can also be the carriers of new diseases or diseases similar tosyndromes whose dynamics are unfortunately very little understood (AIDS, MadCow Disease, etc…), and whose origin is still very vague (perhaps transgenicviruses?).There is ample bibliography on viruses used in GMOs.It is well known that CaMV (Cauliflower Mosaic Virus) is used today in the replication of retroviruses introduced in theplants by GMO multinationals in order to modify their DNA (GMO plants).This virus is active both in angiosperms and gymnosperms, i.e. in all plants.This virus is used by GMO multinationals to modify genetically plants because it contains particular promoters, whichare “motors” which drive genetic activation.CaMV has two promoters: 19S and 35S.Of these two the 35S promoter is most frequently used by multinationals.The 35S promoter is a DNA sequence of about 400 bases (units of genetic sequence of four different molecules:Adenine, Cytosine, Guanine or Thymine).84

The CaMV promoter is preferred above other potential promoters used by GMO multinationals to modify plantsbecause it is not influenced by the different conditions of vegetable cell tissue types and thus it can act.Unfortunately it is able to penetrate and replicate in animal cells, including mammalian and human cells, asdemonstrated by Vlasak in a study published in 2003. Vlasak J.: Comparison of hCMV immediate early and CaMV 35Spromoters in both plant and human cells, Journal of Biotechnology No. 103, pages: 197-202, 2003)http://www.dirittolibertadicura.org/images/OGM/vlasak.pdfhttp://www.mednat.org/alimentazione/vlasak.pdfThese artificial pararetroviruses are created and used by multinationals to modify the DNA of plants. They are similar toretroviruses already present in nature, such as: HIV retrovirus of AIDS, HUMAN LEUKAEMIA retrovirus, Hepatitis Bretrovirus (Bonneville: Retrovirus, Viroids and RNA recombination, RNA Genetics, Vol. 11, pages: 23-42, 1988).According to scientific literature, CaMV is closely related to the virus of human hepatitis B and AIDS. (Doolitte:Quart.Rev.Biol. 64, 2, 1989) ; (Xiong and Eickbush, Origin and evolution of retroelements based upon their riversetranscriptase sequences EMBO Journal 9, pp. 3353, 1990http://www.mednat.org/alimentazione/EMBO%20JOURNAL%201990.pdf )Using CaMV in plants eaten by humans and/or animals can be very dangerous and hazardous because of the GENETICRECOMBINATION of DNA chromosomes in the plants. This can lead to the recombination of the 35S promoter itselfwith the DNA of the person or animal that has eaten fruit, vegetables, pasta or GMO soya containing thesepararetroviruses.Through GENETIC RECOMBINATION, the viruses can also include cell genes present in the animal that haspreviously eaten that GMO plant. These can reach the man who has eaten that animal causing totally unknown geneticeffects.One the most likely consequences is the outbreak of cancers and leukaemias.Genetic modifications to progeny can be another consequence.In these cases, the DNA system would be disrupted as happens in the case of exposure to ionizing radiations.However, differently from ionizing radiations, there would be also the risk of new infectious diseases.NEW INFECTIOUS DISEASES: it has been demonstrated that the CaMV genes incorporated into the plant (canola)chromosomes recombine with infecting viruses to produce new, much more virulent diseases.This experimental model concerning the safety of transgenic plants containing viral genes such as CaMV was presentedby GAL in a study published in 1992: Gal S.: Agroinfection of transgenic plants leads to viable Cauliflower MosaicVirus by intermolecular recombination, Virology, No.187, pages: 525-533, 1992http://www.dirittolibertadicura.org/images/OGM/gal.pdf ; http://www.mednat.org/alimentazione/Gal.pdfAbout recombination between CaMV and viruses involving the promoter see also Vaden’s paper published in 1990:Ray Vaden: Recombination sites in Cauliflower Mosaic Virus DNAs; implications for Mechanisms of recombination,Virology, No.177, pages: 717-726, 1990 http://www.dirittolibertadicura.org/images/OGM/ray%20vaden%20.pdfhttp://www.mednat.org/alimentazione/Ray%20Vaden%20.pdfOther scientific studies demonstrated that recombination of these retroviruses may take place either between DNA andDNA or RNA and RNA, thus creating new viral infections (Mol.Plant-Microbe Interactions 5, 48, 1992).Similar related experiments suggest that altered plants may cause deadly diseases, as shown by Greene in 1994:Greene A.E.: Recombination between viral RNA and transgenic plant transcripts, Science, Vol. 263, 11 march 1994http://www.dirittolibertadicura.org/images/OGM/greene.pdf ; http://www.mednat.org/alimentazione/Greene.pdfVery dangerous viral DNA chains produced by normal RNA viruses are frequently propagated in the vegetableenvironment (GMO plants) using the CaMV 35S promoter to drive the production of RNA viruses which otherwisecould not propagate in the plant DNA. From here they could pass to the animal DNA (man included) or in the bacteriaor viruses DNA. Boyer J.C.: Infectious transcripts and cDNA clones of RNA Viruses, Virology, No. 198, pages: 415-426, 1994 http://www.dirittolibertadicura.org/images/OGM/boyer.pdf; http://www.mednat.org/alimentazione/Boyer.pdf85

In conclusion: promoters recombine with the infecting viruses to produce virulent new diseases.CaMV viruses and its promoters 19S and 35S may incorporate genes from the host plant or animal or bacterium DNA –or even from a DNA virus – creating virulent new diseases.In case of a DNA virus, CaMV can recombine with insect DNA viruses, thus propagating in the insect cells.(Zuidema D.: J.Gen.Vir. 71, pages 312, 1990) http://www.mednat.org/alimentazione/zuidema.pdfAs a consequence, it is likely that by eating tomatoes genetically modified with CaMV (recombined for example withhepatitis B viruses) a large number of people could create a SUPERVIRUS able to propagate in plants commonly usedas food and in insects – such as mosquitoes – and then reach the man.Allison R.F.: Recombination in plants expressing viral transgenes, Seminars in Virology, Vol. 7, pages: 417-422, 1996http://www.dirittolibertadicura.org/images/OGM/allison.pdf; http://www.mednat.org/alimentazione/Allison.pdfWintermantel W.M.: Isolation of recombinant viruses between Culiflower Mosaic Virus and a viral gene in transgenicplants under conditions of moderate selection pressure, Virology, No. 223, pages: 156-164, 1996http://www.dirittolibertadicura.org/images/OGM/wintermantel.pdfhttp://www.mednat.org/alimentazione/Wintermantel.pdfLatham J.: GM Gene Flow (B): Horizontal gene transfer of viral inserts from GM plants to viruses, Technical paper,February 2004J.T.Dessens: Cauliflower mosaic virus 35S promoter-controlled DNA copies of cowpea mosaic virus RNAs areinfectious on plants, Journal of General Virology, No.74, pages: 889-892, 1993http://www.mednat.org/alimentazione/dessens.pdfSteinbrecher R.A.: The CaMV 35S Promoter Government and Corporate Scientific incompetence: failure to assess thesafety of GMO crops, Econexus Briefing, December 2002Mae Wan Ho: The CAMV 35S Promoter fragmentation hotspot confirmed, and it is active in animals, MicrobialEcology in Health and Disease 2000, 12, págs: 189 ; http://www.mednat.org/alimentazione/MaeWanHo1.pdfMae Wan Ho: Cauliflower Mosaic Viral Promoter – a recipe for disaster, Microbial Ecology in Health and Disease1999, 11, pp: 194-197 ; http://www.mednat.org/alimentazione/MaeWanHo2.pdfFIFTH POINT: intoxication by poisons synthesized from transgenic plants.Chronic poisoning of foods caused by the toxic substances in insecticides which are used on plantsto make them resistant to parasites as Bacillus touringiensis ( 789-793 ), with the consequent increase incancer, miscarriages, genetic mutations in descendants, Acquired Immunodeficiency Syndrome,degenerative diseases and diseases caused by toxic substances, etc.In Italia, il gruppo di ricerca dell’Istituto Nazionale di Ricerca per la Nutrizione e gli Alimenti guidato dalla dott.ssaMengheri ( 1750 ) http://www.mednat.org/alimentazione/Finamore.pdf ) ha effettuato uno Studio di valutazione deglieffetti del mais MON810 sul sistema immunitario, sia intestinale che periferico, dei topi, con particolare riguardo alleimplicazioni legate allo sviluppo e all’età anziana. Infatti è noto che durante lo sviluppo e la vecchiaia il sistemaimmunitario può rispondere con minore efficienza agli stimoli esterni rispetto a quanto accade in un adulto sano. Irisultati dopo 30 e 90 giorni di alimentazione provano che, al contrario di quanto accade con il mais naturale, con ilMON810 si sono verificate alcune alterazioni.Queste alterazioni sono risultate più marcate, e quindi più gravi, proprio a carico dei topi durante lo sviluppo enell’invecchiamento. Inoltre, dall’analisi proteomica è risultato che nel mais MON810 la regolazione di ben 43 proteineha subito modifiche rispetto al mais normale, e che tra queste risulta presente una nuova versione della proteina gammazeina….Teerje Traavak, direttore del Norwegian Institute of Gene Ecology, nel 2004 affermò di aver documentato il primo casodi seri effetti nocivi alla salute umana causati da piante OGM, in particolare dovute a intossicazione dal polline del maisOGM arricchito con Bacillus Thuringiensis , colpiti da disturbi respiratori ed eruzioni cutanee. Gli esami del sangue,condotti su 39 contadini filippini, avrebbero infatti dimostrato anticorpi contro la tossina del Bacillus Thuringiensis. Ma86

la cosa più inquietante di questo preziosissimo lavoro del prof. Traavak fu poi quello di aver trovato il Promoter 35Scioè il para-retrovirus impiegato per introdurre nel mais OGM il gene del Bacillus Thuringiensis, addirittura nelle stessecellule umane dei contadini, con dimostrata quindi sua pericolosità di indurre modificazioni genetiche nel DNA umano,e quindi tumori maligni, confermando quindi i lavori precedenti di Vlasak del 2003. (L’ESPRESSO, 9 APRILE 2004)Interessante anche il recente lavoro ( 2003 ) uscito in Francia di Joel Spiroux de Vendomois, che ha dimostrato la citotossicitàepato-renale di tre varietà di mais transgenico (NK 603, MON 810, MON 863)http://www.mednat.org/alimentazione/OGM_mais_studio_franc.pdf .SIXTH POINT: danger of worldwide famine due to TERMINATOR technology.Passing to natural “indigenous” species of wheat, rice, sweet corn, potatoes, legumes, becausevegetables themselves cannot reproduce themselves the normal way due to TERMINATORtechnology; this is caused by cross pollination, and it also causes irreversibly the loss of naturalvegetables that are nowadays used as food by humans, as vegetables will be polluted by thetransgenic genes coming from transgenically cultivated areas (GM) where TERMINATORtechnology is used.Therefore there is a potential menace of global famine in the future, something that cannot becontrolled, as the world will not have sufficient quantities of wheat, rice, sweet corn, legumes, theway they are in nature, or anyway not of the TERMINATOR kind.SEVENTH POINT : transgenic pollution of natural plantsThe transmission to ‘native’ natural species of artificial toxic substances as Bacillus touringiensis( 789-793 ) by means of cross pollination, with a potential threat also to the plants and herbs used todayin herbal remedies, because the latter will also become polluted by the transgenic genes comingfrom the agricultural areas devoted to transgenic cultivation (GMO).EIGHTH POINT: the irreversible disappearance of natural plantsThe gradual and irreversible disappearance of biological diversity, that is of the normal, naturalflora. Transgenic cultivation will pose a serious threat to those areas which are rich in biodiversity(natural genomes); the transgenic flow which will go from modified plants to natural plants will beinevitable when the numerical ratio between areas cultivated with artificial plants exceeds the areasof natural plants, thus causing the irreversible loss of a great part of the natural genetic patrimony ofall the plants existing in the world: at present there are about 442,000 species already classified outof an estimated total of 600,000 – 800,000 species.In short:Numerous plants have already disappeared during the last few years because farmers haveabandoned natural plants in favor of adopting artificial plants, that is, genetically modified plants,because they are uniform in their genome and they give a high production (but are poor invitamins). They are intrinsically sick (because they are incapable of surviving without pesticides),they are made sterile for economic reasons, and finally they are genetically manipulated to makethem resistant to insects and other animals because they themselves are capable of producingpoisons, that is, toxic substances which are eaten by farmyard animals and so passed on to man.Even in the forests genetic variety is threatened today by the loss of habitat, not only caused byincorrect deforestation practices, but also by the contamination of the genetic patrimony (which hasadapted to local situations) by hybrids created by large seed Companies which produce GMOs.87

Chap.2.23.: Allert G.M.O.:The USA are passing a law that legalizes the contamination of cropswith genetically modified organisms (GMO). Source: Friends of theEarth International (DECEMBER 2004)The FDA is about to publish what can certainly be considered the law that legalizes thecontamination of food with transgenic substances. The policy recently adopted by thisgovernmental entity sets scandalously rough guidelines for a company to deliberately follow andthereby obtain from the FDA itself the approval and acceptance to use transgenic substances thatare still in the experimental phase.This superficial and inadequate procedure supplies companies with legal protection in case ofcontamination and guarantees the authorisation of their own experimental seeds that are thereforeimmediately introduced into the food chain. What’s worse, as over two-thirds of OGM underexperimental cultivation in the USA contain genes whose specific characteristics are considered of“confidential nature”, at present there is no way of getting to known more about what they contain.Consequently, for the very fact that laboratories cannot obtain this essential information, they areunable to trace their presence in foodstuffs on the market, with obvious serious repercussions on theactivity of all those firms and companies who are constantly striving to avoid the contaminationphenomena.Chap.2.24.: RUSSIA, GM Food Dangers Directly Affect BiologicalDescendants and Future Generations, of Robin Good,MasterNewMedia.org 1 November 2005.A breakthrough study from a national Russian research agency suggests that a diet with geneticallymodified(GM) soy may indeed affect newborns of parents maintaining a GM-based food diet.According to the study reported by Russian federal news agency Regnum News Agency, GM foodscan affect “the posterity of humans and animals”.This is the first research that determined clear dependence between eating genetically modified soyand the posterity of living creatures.The study that included this information was presented on Oct. 10 at a symposium on geneticmodification, a program organized by the National Association for Genetic Security (NAGS).The study has been conducted by a team of researchers led by Irina Ermakova, Doctor of Biology,at the Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy ofSciences (RAS).During the experiment, doctor Ermakova added GM soy flour to the food of female rats two weeksbefore conception, during conception and nursing. In the control group were the rat females thatwere not added anything to their food.88

“For the study, the scientists used GM soy flour in a diet for female rats two weeks before and during conception, andafter birth.Three groups of rats were assigned a different diet each: a control group received no soy, the second group received GMsoy flour, and the third group received conventional soy flour. The scientists counted birth and death after the offerings.Three weeks after birth, the death rate of the baby rats was counted for each group.It was found that both the conventional soy and the GM soy did not affect the number of baby rats each motherproduced.However, the death rates of baby rats in three weeks after birth were drastically different.The death rates for the control, the group raised by mothers on a GM soy diet, and the group raised by mothers on aconventional soy diet were 6,8 percent, 55,6 percent and 9 percent respectively.The results indicate that conventional soy did not have a negative effect on the death rate, while a GM soy dietincreased the death rate by a factor of eight.Also, 30 percent of the babies in the GM soy group had an abnormal weight of less than 20 grams…”.The morphology and biochemical structures of rats are very similar to those of humans, and this makes the results weobtained very disturbing”Irina Ermakova, told the NAGS press officeSEE: Ermakova IV, “Genetically modified soy leads to the decrease of weight and high mortality of rat pups of the firstgeneration”, preliminary studies. EcosInform 2006, 1, 4-9 (in Russian). Full paper : Ermakova IV, Genetics andecology, in: Actual problems of science, Moscow , 2005, pp.53-59 (in Russian).Chap. 2.25.: GMO–Terminator: the new threatFrom ETC Group, 13 June 2007Today ETC Group reports on a new crop of genetic engineering technologies that are beingpromoted as a biosafety solution to the unwanted spread of transgenes from GM crops, trees andpharmaceutical-producing plants. In practice, these technologies, if commercialized, will allow themultinational seed industry to tighten its grasp on proprietary seeds and to restrict the rights offarmers.The 28-page Communique begins with an examination of the European Union’s “Transcontainer”project, which is developing GM crops and trees for Europe that could be “biologically contained”through “reversible transgenic sterility”. The three-year project, which is part of the EU’s SixthFramework Programme, supports the goal of “co-existence”- the controversial idea that GM cropsand non-GM crops can peacefully co-exist – and it aims to promote public acceptance of GM crops.“We’ve always known that Terminator technology is simply too lucrative for the seed industry toabandon,” says ETC Group’s Hope Shand, “but it’s outrageous that the European Union is usingpublic funds to develop genetic seed sterilization”.Shand adds, “The EU-funded Transcontainer project is especially disturbing in light of theEuropean Parliament’s strong anti-Terminator stance only last year.” The European Parliamentpassed a resolution in March 2006 urging European delegates meeting at the CBD (United NationsConvention on Biological Diversity) in Curitiba, Brazil to uphold the de facto moratorium onTerminator. At the meeting governments unanimously re-affirmed and strengthened themoratorium, which recommends against the field-testing or commercialization of seeds that havebeen genetically engineered to produce sterile seeds at harvest. The United Nations uses the termGURTs (genetic use restriction technology) to refer to TERMINATOR.89

Apologists for the Transcontainer project argue that its aim is not to restrict seed use but to containtransgenes, and that the technology under development differs from Terminator because the seed’ssterility will be “reverible”, so that seed fertility can be recovered – most likely through theapplication of a chemical. Hope Shand counters, “A scenario in which farmers would have to payfor a chemical to restore seed viability creates a new perpetual monopoly for the seed industry.Even if these “Zombie seeds” are not being designed with the intent to restrict seed use, the realityis that farmers will end up having to pay for the privilege of restoring seed fertility every year.Zombie seeds are no more acceptable than suicide seeds – there is simply no such thing as a safeand acceptable form of Terminator” , adds Shand.ETC’s report also examines new research on gene excision technologies (i.e., molecular methods tosnip out transgenes at some point in a plant’s life). Dubbed Exorcist by ETC Group, the technologyis a strategy for both ciocontainment and for restricting access to proprietary germplasm. In theory,DNA-excision could be designed to occur at any stage during the plant’s development – before theGM plant flowers and produces pollen, for example, or before it becomes food. The excisionprocess can be triggered by an external environmental or chemical stimulus, or excision can bedesigned to occur automatically at a particular stage in the plant’s life. ETC’s Kathy Jo Wetterexplains, “In its current state, Exorcist is far from a failsafe biocontainment strategy – it won’twork 100% of the time – but even if Exorcist can’t fully contain transgenes, it could still function asa biological method to enforce patents by restricting access to proprietary traits.”Finally, ETC Group’s Communique examines “extreme” biocontainment methods – molecularmethods involving “conditionally lethal genes” capable of terminating plants and their transgenicDNA in the event that other containment strategies fail.The idea is that a “Pull-the-Plug” plant could be killed by triggering the lethal gene – by theapplication of an external chemical, for example – taking the GM train down with it. If the lethalgene is not triggered, the plant lives and can pass on its foreign genes to the next generation.Ostensibly, these pull-the- plug plants are being developed as a back-up strategy for last-resortbiological containment.“There’s also a more sinister possibility”, suggests ETC’s Silvia Ribeiro, “that companies couldpull the plug on plants they believe are being grown without the proper licensing agreements.We’ve already seen biotech companies resort to nasty companies could threaten to trigger thelethal gene or they could simply apply the chemical trigger to get positive or negative confirmationwhen they suspect the farmer of patient infringement”.Ribeiro concludes : “ Zombie seeds, Exorcist seeds and Pull-the-Plug plants: these are all defectivetechnologies that won’t prevent the unwanted spread of transgenes from GM crops. But ifgovernments can be convinced that biological containment of GMOs is possible using one of thesenew technique – or a combination of them – it will open the floodgates to new markets for biotechplants, particularly GM crops and trees grown for biofuels. The result will be more heavilysubsidized multinational companies and drastically increased risk of transgenic contamination”.Governments meeting in Rome at the FAO’s Commission on Genetic Resources for Food andAgriculture are today considering a “code of conduct” on biotechnology.“If anyone needs more evidence of the urgent need for a biotech code of conduct, Zombie seeds andsuicide seeds are it”, says Pat Mooney of ETC Group.Civil society organizations convening in Berlin next week (June 18-21) at the Second EuropeanForum on Sustainable Rural Development should consider requesting that the European90

Commission cease funding for Zombie seed research, particularly because of its dangerousimplications for 1,4 billion people who depend on farm-saved seeds.ETC Group’s report concludes with recommendations related to these “dual use” GURTs – newgenetic modification techniques designed to contain transgenes and restrict access to proprietarygermplasm. The CBD’s scientific advisory body (SBSTTA) meeting in Paris, France, 2-6 July 2007should recommend that governments meeting at the 9 th Conference of the Parties to the CBD(Bonn, Germany, 19-30 May 2008) strengthen the United Nations’ moratorium on Terminator byrecommending a ban on the technology.Chap. 2.26.:How the European Union destroys the European AgricultureExtracted from “Salute e Diritti”, “Health and Rights”, 2004, No. 1;Quarterly review about COMILVA FEDERATION,i.e. Coordinamento del Movimento Italiano per la libertà dalle Vaccinazioni(Coordination of the Italian Movement for Free Choice from Vaccinations).An attempt to make small producers die – to big producers’ advantage– and agricultural production decreaseWe are witnessing the attempt to make small producers die and make the agricultural productiondecrease through laws regulating fruit and vegetable markets and a premium policy aimed atfavouring little productive woods and giving premiums regardless of production (for examplepremiums for those who once cultivated fields fit for seed); through obstacles to direct saleproducer-consumer; through obstacles to production for private consumption; through disappearanceof the simplest, least expensive and maybe most effective phytopharmacons; through protection ofpredators of insect-eating birds and – excessively– animals harmful to agriculture; through a lack ofinterest for a scheduled biological fight against phytophagouses, which could be effective and lessexpensive; through no reforestation of deforested mountains and no intelligent programmes againstfires; through no cultivation of very productive and valuable tree species; through spread – eventhough not wanted – of strange diseases whose responsible organisms are basically the samecultivated in the laboratories of biological war.91

Chap. 2.27.: Effects of European rules concerning the size of fruit andvegetable markets on agricultural productionIn Brussels, around the European Commission – the government of Europe – there are 3,000“pressure lobbies” with 10,000 people. These lobbies have a great influence on decisions inimportant sectors, such as economic policy, agriculture, etc… Thus we can understand someEuropean recommendations aimed at promoting the commerce of low-quality food products: poorqualitychocolate, pasta and bread; the ban on cooking pizza in wood-burning ovens; mozzarellaproduced exclusively with powdered milk; authorization to grow GMO viticulture; milk quotas;bananas which must be longer than a certain length so that African short bananas cannot be sold andAmerican long bananas – belonging to Multinationals – can be imported; aubergines which mustexceed a certain length so that cooking filled aubergines – for this plate short aubergines arenecessary – could be no longer possible; apricots with a minimum diameter of 30 mm; asparaguseswith a length ranging from 12 to 27 cm; artichokes with a diameter over 6 cm, the bitterness test forlupines, which is really a complex process. For melons it is necessary to measure the percentages ofweight and diameter of the biggest as against the smallest contained in the same package. As far aspeas are concerned, the persecution continues by banning those from pods with less than 5 seeds;moreover, seed pods are analysed manually in order to know by the feel whether they are full. Thequestion is: can food quality be measured in centimetres? Should everything which does not followthe above-mentioned rules be thrown away even though it has excellent taste and nutritional value?The above-discussed rules would:1) put out of market small producers who merchandise on their own and haven’t any graders andsensors to know – for example – how many peas there are in a seed pod;2) because of high waste, decrease the price that canning industries have to pay for raw products, tothe detriment of innocent farmers and without any benefits for consumers;3) decrease the production of fresh products – so the amounts of vitamin and minerals in foods –thus increasing their price;4) urge producers to pump water and chemical fertilizers into products in order to respect establishedlimits, obtaining vegetables and fruit which are less preservable as they contain much water and littledried substance, little tasty because water dilutes the taste, and modified in their composition aschemical fertilizers affect the soil equilibrium causing unforeseen chemical reactions. Withoutknowing, consumers would pay more for the same weight, thus buying more water;5) increase the profits of Multinationals which produce chemical fertilizers;6) weaken the trees because of chemical fertilizers and make them die prematurely;7) increase the number of pesticides as higher amount of water in fruit and vegetables make themmore susceptible to parasites;8) increase the profits of Multinationals which produce fertilizers and pesticides;9) allow trees to be replaced in advance with others which are “protected by patent” (GMO), thusforcing producers to sell products to a certain wholesaler. In this way all the production would be inthe hands of few wholesalers who could impose their price controls on producers and consumers andprescribe their production rules and the use of pesticides and chemical fertilizers.92

Chap. 2.28.: Brussels bureaucracy authorizes parasitical revenuesWho sowed wheat between 2000 and 2002 is entitled to receive a yearly income of 450 euros from2004 to 2013 for every hectare, regardless of the type of crop, even if the land is left barren. Thiskind of policy aims at favouring some big landowners who always cultivated wheat between 2000and 2002 in order to benefit from EU premiums, thus not caring about the right agricultural practiceaccording to which a crop cannot be planted on the same soil for two consecutive years (in this casethe repetition occurred three times). In 1999 the European Commission should have established thatwheat premiums would be given for the same soil only on alternate years. Furthermore premiumsgiven only to arable crops cause a decrease in the surface cultivated with vegetables, fruit and winein order to obtain premiums. i.e. sure money. As far as premiums are concerned, it occurred that in ashort time some land owners obtained financial support to uproot their vineyards and then to plantthem again.It would be simpler to eliminate taxes on agriculture instead of giving financial support. In this waythe double bureaucracy – paying taxes and receiving Aids – would be eliminated (it seems that Aidsare higher than taxes). So European bureaucrats and national bureaucrats could not favour their ownfriends and control agricultural sector depending on the interests of the world ‘s owners.Chap. 2.29.: Obstacles in the way of the Direct Sale from Producers toConsumersDirect marketing from farmers to consumers should be permitted and favoured in order to decreaseconsumer prices and at same time increase farmer incomes. Obviously small farmers would be themost concerned.But unfortunately the law excludes right them as it provides that farmers must be registered –through an onerous registration – with the Chamber of Commerce. Farmers with an income lowerthan 5 million lire cannot register. Moreover the mayor’s authorization or a statement are needed, aswell as, according to the cases, a permit issued by the Local Health Unit stating the appropriatenessof venues to be used for sale (Terra e Vita, No. 19/2002); in addition to that, farmers should havescales enabling them to reset weight after measuring the tare and have them checked by the Chamberof Commerce in charge of the territory on a three-yearly basis (Terra e Vita, No. 9, 2001); in certaincases a social insurance card might be required. As far as olive oil is concerned, small producers arepractically excluded from the direct sale. The new law provides that olive oil must be bottled,labelled and packed in containers holding no more than 5 litres. Oil cannot be sold loose. As regardswine, the bureaucratic fulfilments are monstrous (Terra e Vita, No. 35/2004).Is the farmer free at least to breed some animals for his own consumption?No, he is not. He is not even allowed to do that. Who has more than 10 birds – geese, ducks,chickens, turkeys, etc. – if they are not ornamental animals must have the mayor’s authorization andcommunicate the possession of these animals to the Local Health Unit, even though the activity iscarried out in a place isolated from the world. If you want to breed a kid you must have all necessaryauthorizations, statements, registers and every kind of papers. Moreover, if the animal dies you mustbring it to the incinerator and spend much money, even though it would be easier to bury it. If youwant to slaughter a lamb – besides registering it in a special register within 20 days from its birth andmaking its ears punched so that it can have a label like a parcel – you are not allowed to do that onyour own; you must bring it to a slaughterhouse where you will pay for operations that you could do93

alone. It is clear that everything is against small farmers who are not even allowed to produce fortheir own consumption. Only big farmers are free to produce, above all in those countries consideredsuitable by the World’s owners, where there is no bureaucracy; in Italy and Europe we are allowedto produce only “bolts”. For this reason French farmers violently protest as well as Italian breeders,who are oppressed by milk quotas. The whole agricultural sector is suffering.Chap. 2.30: The Non-GMO ProjectRegrettably, there is a long-standing practice of “Don’t ask. Don’t tell” in the natural productsindustry regarding genetically engineered derived food and ingredients. Most commonly, inquiriesare deflected by simply saying that GMOs are “not allowed in the USDA organic program” eventhough no one is testing or doing anything to avoid them.Eden, however, is and has been doing everything necessary to avoid them since 1993.Recently, the Non-GMO Project (The Project) was created by industry members from all of itssectors in the USA and Canada. Eden Foods being one. The Project aims to provide consumers andmakers a 3 rd party non-GMO verification program through all levels of the supply chain, thusproviding verified non-GMO alternatives to the consumer. Eden F oods is enthusiastic in support ofthe Project and has great hope that it will become a much-needed filter that knowledgeable peoplerequire.Eden Foods, its president Michael Potter, is one of eleven governing members of the Non-GMOProject’s board of directors that has been involved in initiating, funding, and writing standards forthe Non-GMO Project, a non-profit organization to develop and verify consistent standards for foodproduced without genetic engineering or recombinant DNA technologies. The Non-GMO Project isNorth America’s first independent non-GMO verification utilizing on-site facility audits, documentand systems reviews, and DNA PCR (Poliymerase Chain Reaction) testing of all inputs at risk forGMO contamination.The Project aims to continuously improve elimination of GMO contamination along the supplychain by encouraging suppliers of Non-GMO seed, to pffering information concerning companiesthat have enrolled their food in the Non-GMO Product Verification Program.As of today Eden enrolled 79 foods that have all been verified as compliant with the Non-GMOProject Standard.View List of Verified Eden FoodsView Non-GMO Project Certificate of ComplianceTo learn more about the Non-GMO Project visit:www.nongmoproject.orgtwitter.com/nongmoproject94

Chapter 3 :Anti-oxidative nutritionThe simplest way to obtain these natural phyto-chemicals is through nutrition (SEE chap. 1). Adaily diet should be based on 8-10 servings of fresh, biologically grown vegetables, well washed (atleast four times), fresh fruit, seeds, green leaf vegetables and tubers. The choice of foods is veryimportant, they must be guaranteed to have been grown free of any anti-parasite solutions and/orpesticides, given the widespread pollution of the environment existing in Europe today.Supplementing such a diet with fruit and vegetable juice concentrates improves the immune defensesystem. The cyto-toxicity of the Natural killers can increase from 25 to 100 times, with significantincreases even in Interleukine 2, Interleukine 6 and a proliferation of the T cells ( 630 ).Furthermore, the same addition of fruit and vegetable juice concentrates reduces the oxidativedamage to the DNA of the peripheral lymphocytes by about 60% ( 631 ).Of the common carotenoids contained in food, beta-Carotene, alpha-Carotene, Lycopene, Lutein,Zeaxantine and Cantaxantine have demonstrated a potent anti-oxidative, immune-modulating actionand the possibility of influencing the genetic expression, improving the ratios of intercellularconnection bond ( 635 ). http://www.mednat.org/alimentazione/Nacci_vitamine%209.pdfThe carontenoids Lutein and Zeaxantine, which are found mainly in dark green leaf vegetables (e.g.spinach), have also proved to be effective.Table 5:Hematic values to be searched for, according to the anti-oxidative levels present in cancer patientswith an Immune Cascade under way:Total TocopherolAlpha-TocopherolGamma-TocopherolTotal carotenoidsLipidic profileGlutathionePholatesVitamin B12Lipidic peroxides (e.g. Malondialdeide)Urinary levels of 8-hydroxic-DeoxiguanosineAnti-oxidant reserve capacity of the hematic serumHigh levels of natural anti-oxidants such as carotenoids, tocopherols and ascorbic acid have beenstudied, to test eventual positive changes in the pathologic progress of serious illnesses such ascancer. The long term practical studies have almost always shown that single nutrients like beta-Carotene have disappointing results, because the anti-oxidants are effective only when combinedand taken in a wide spectrum (at least 13,000 vitamin principles and co-enzymatic factors ofdifferent types). Thus, the respective levels of carotenoids and of Tocopherol in human plasma havebeen measured, following the integration into the diet of commercial extracts of fruit andvegetables. Then, the effectiveness of this integration in modifying the oxidizing processes was95

established, measuring the levels of the lipidic peroxides present in the hepatic serum: 15 healthyadults took these commercial extracts twice a day, at mealtimes, for 28 days; samples of plasma andserum were taken before the start of the study, and at day 7, 14 and 28.After 28 days, the anti-oxidative levels in the blood, especially Lycopene, increased to a significantextent:Beta-Carotene: + 510%Alpha-Carotene: + 119%Lutein/Zeaxantine: + 44%Lycopene: + 2046%Alpha-Tocopherol: + 58%Retinol: + 14%On the contrary, the level of lipidic peroxides in the blood serum decreased by 4 times after 7 days,stopping at a level of -75%. The decrease in the level of lipidic peroxides coincides with an increasein the carotenoids and alpha-Tocopherol, as a logical consequence of the functional improvement ofthe defense mechanisms against oxidation.Similarly, gamma-Tocopherol also showed a drop in the hematic concentration (-38%), because ofthe continuous oxidative stress by the normal flora bacteria; this anti-oxidative process guaranteedby gamma-Tocopherol is due to the liver and the bio-availability in the diet of alpha-Tocopherol.When the latter is present in adequate amounts, gamma-Tocopherol is "consumed" in particularparts of the body such as the intestine, thus showing a slight but continuous level of lowconcentration. Vice versa, when there is a lack of alpha-Tocopherol, the liver tends to save theconsumption of gamma-Tocopherol, thus raising the hematic levels of the latter ( 636 ).Another experiment ( 638 ) which integrated commercial extracts of fruit and vegetables into the dietof 16 adults, showed the following values of plasmatic concentration after the seventh day oftherapy:1) beta-Carotene: increased to stable hematic concentrations of 0.5 microMols/liter2) vitamin C: increased to about 3 times as much, reaching stable hematic concentrations of 60microMols/liter3) vitamin E: increased up to stable hematic concentrations of 3 microMols/liter4) malondialdeide plasmatic level, considered a general peroxidation indicator, decreased by about40%.In another experiment ( 638 ), which integrated commercial extracts of fruit and vegetables into thediet, after 3 months of supplementing the diet with 18 milligrams a day of beta-Carotene, 900milligrams of vitamin C and 200 milligrams of alpha-Tocopherol, the plasmatic concentrationsincreased respectively by:Beta-Carotene: + 500%Vitamin C: + 55%Alpha-Tocopherol: + 27%An integrated dietEight-ten portions a day of fresh fruit and vegetables is a strict regime to follow both for the patientand the family, because it implies a continuous feeding program, but it must be followed, perhaps insmall portions.The author considers that it is necessary, for an anti-oxidative effect, to integrate fresh vegetables(fruit, vegetables, green leaf vegetables and tubers) with the products already listed in chapter 1.96

Chap. 3.a.: Retinoids and Carotenoids:Axerophthol palmitate, Beta Carotene and Trans-Retinoic AcidThere is an extensive bibliography on the anti-tumoral action of Vitamin A( 1,3,10,13,14,17,18,23,24,28,34,35,36,45,56,69,73,76,92,93,94,100,106,111,120,121,129,131,137,138,165,187,200,202,203,208,209,212,213,214,216,218,222,235,255,256,257,263,264,265,266,280,282,286,287,288,298,303,304,305,307,313,315,322,324,325,326,334,338,340,341,347,348,352,354,362,363,365,382,383,385,390,398,402,404,405,409,410,420,425,426,427,445,446,447,448,454,457,461,463,468,469,470,471,473,477,488,493,508,512 ).In particular the combined use of Retinoids in the proper proportions (beta-Carotene: retinol = 4 :1), establishes a synergism which is higher than the sum of the single components.According to the author it would be better to use the juice of Daucus carota (carrot) made from rawand biologically grown carrots, rather than the synthetic pharmaceutical vitamin products based onVitamin A.Anti-tumoral action in generalVitamin A and retinoids have an anti neoplastic action, shown both in vivo and in vitro, in varioustumors: basilomas, scaly carcinomas, melanomes, skin cancers, fungoid mycosis, acutepromyelocyte leucemia, ovarian cancer, breast cancer, lung cancer, cancer of the bladder andfollicular carcinomas of the thyroid.Preventative actionAnti-tumoral action has been amply shown indirectly, that is with a preventative purpose. Variousstudies have, in fact, shown that low plasmatic levels of beta-Carotene, vitamin C and vitamin E areconnected to an increase in the incidence of lung cancer.Direct action at a receptor levelOnly beta RAR (retinoic acid receptor) seems to be involved.More specifically, vitamin A (and its derivatives) acts by binding with specific receptors. In thisway it can both inhibit the proteic synthesis of DNA and RNA, and also perform an anti-promotionaction to determine the return of a cellular differentiation. Furthermore its ability to inhibitoncogenes should be noted.Apoptosis induction (SEE chap.6.a)Apoptosis means the activation of specific endonucleases which break up the DNA, acting at a levelof nucleosomic sites that make up the primary structural unit of the nuclear cromatine of the cell.Vitamin A and retinoids in general can induce apoptosis in neoplastic cells, by activatingintracellular proteolytic enzymes, called caspase 2 and caspase 3, which provoke deteriorationthrough proteolysis by a transcription factor, called Spl.If this basal cellular transcription is altered, death is caused by Apoptosis.In prostate cancer the retinoids intervene by reducing the level of the bcl 2 gene, whose function isto protect the cells from death by Apoptosis.Carotenoids induced apoptosis in prostate cancer ( 1366 )http://www.erbeofficinali.org/dati/nacci/studi/carotenoidi%20sono%20fattori%20attivi%20contro%20il%20cancro%20della%20prostata.pdf97

Inhibition of the cellular cycleThe retinoids block the passage of the cell from phase G1 to phase S (reducing the activity of aprotein, called cycline D1): this passage, if not blocked, would lead the cell to mytosis.Reduction of phosphorilationRetinoids intervene in cancer causing a reduction in phosphorilation of the pRb, thus increasingsurvival; this protein is active in suppressing cellular growth.Synergetic interaction with interferonsA second mechanism, apart from the proteic-enzymatic one, can be traced back to the interventionof interferons which, like retinoids, act as anti-proliferative factors. In practice, actingsynergetically, they induce the expression of proteins capable of inhibiting neoplastic cellularproliferation.The intake of natural carotenoids from foodThere is very little evidence to show that carotenoids taken in from food can increase the levels ofvitamin A: an extra portion a day of green leaf vegetables is not able to increase the hematic level ofvitamin A; on the contrary, a mixed diet of foods particularly rich in beta-Carotene will give asignificant increase in vitamin A present in the blood. ( 627 ).If you oblige healthy individuals to eat carrots (270g), broccoli (600g) or tomato juice (180g) itdoes not establish any significant changes in the hematic levels of the carotenoids: you only find anextremely wide variation (even up to 3-4 times) in the efficiency of gastro-intestinal absorption ofthe carotenoids and therefore in their subsequent bio-availability at a hematic level ( 628 )Association of vitamin A with vitamin EIn an experimental model of a cellular membrane the possibility of a positive interaction betweenanti-oxidant liposollubles such as beta-Carotene and alpha-Tocopherol has been investigated; theresult showed that there exists a synergetic action between beta-Carotene and alpha-Tocopheroltogether which inhibits the processes of lipidic peroxidization compared with when they are usedalone ( 629 ).Optimal values of anti-oxidants in normal individualsVitamin C: >50 microMols/LiterVitamin E: >30 microMols/LiterVitamin A: >2.2 microMols/LiterBeta-Carotene: >0.4 microMols/LiterThe difference between synthetic vitamins and natural vitaminsThe difference between synthetic vitamins and natural ones can be easily exemplified by theexperimental case of synthetic beta-Carotene (made up entirely of isomeric trans-beta-Carotene),and of natural beta-Carotene (made up of both isomeric trans-beta-Carotene and isomeric cis-beta-Carotene): the study showed a strong discrimination between the two isomers, with a seriousdecrease (impoverishment) induced at the level of Lycopene present in the LDLs (...).98

Conversion factors of vitamin AVitamin A is expressed in Retinol Equivalents (R.E.)1 R.E. is equal to:= 1 microgram of all the trans-retinols= 6 micrograms of all the trans-beta-Carotenes= 12 micrograms of other active carotenoids= 3.33 I.U.a (International unit of vitamin A)= 10 I.U.c. (International unit of provitamin A from carotenoids)1 International unit (I.U.a.) of vitamin A is equal to:= 0.3 R.E.= 3 I.U.c.= 1.8 micrograms of all trans-beta-Carotenes= 3.6 micrograms of other active carotenoids1 International unit (I.U.c.) of provitamin A from carotenoids is equal to:= 0.6 micrograms of all trans-beta-carotenes= 0.1 R.E.= 0.33 I.U.a.= 0.1 micrograms of all trans-retinols= 1.2 micrograms of other active carotenoids99

Chapter 3.b: Camellia sinensis (green tea)There is a large bibliography on this plant, known in China since ancient times ( 4,5102,123,135,155,173,217,224,274,309,1123,11124,1186 )Basically we get a dry extract from this plant which is used as an infusion: decaffeinated green tea(less than 0.02% caffeine), with a high content of polyphenols titrated in EGCG (EpiGallo-Catechin-Gallate); heavy metals present in irrelevant quantities (As

Chap. 3.c.: Vitamin CThere is also an extensive bibliography on the anti-tumoral action of vitamin C ( 25,33,47,54,83,91,122,129,181,197,202,218,244,246,270,299,311,335,339,367,404,405,414,415,416,489,496,510,511 )The pioneers of this oncological therapy were Pauling, who received the Nobel Prize for Chemistry,and the Italian Pantellini.Ascorbic acid is mainly known for its ability to reduce metallic ions in various enzymatic processesand above all for its ability to act as an anti-oxidant agent, thus able to remove free radicals,reducing the damage caused at a genome level.Furthermore it may be able to block the formation of nitrose at a gastro-intestinal level, as well ascarrying out a preventative action on the formation of adenomatose polyps.Even though ascorbic acid is well known for its collagene forming action, and the well knowneffect of scurvy in cases of reduction or absence of this acid in the diet, this vitamin is alsoimportant, alongside vitamins A and E as a first class anti-tumoral agent.It reinforces the intercellular bond and forestalls the destructive action of the hyalurons produced bymany neoplastic cells.Above all, vitamin C stimulates the Natural killer lymphocytes, it supports the macrophagicactivity, the chemio-tactical mobility of the white corpuscles, the production of antibodies and theresponse of the T cytotoxic lymphocytes to the antigenes.Cameron found very low plasmatic levels of vitamin C in cancer patients (0.26 mg/100 mL)compared to normal plasmatic values ( 54 ).In other studies, 154 cancer patients, undergoing analysis, were found to have low levels of vitaminC not only in their plasma (0.31 mg/100 mL), but also in their leucocytes (15.9 mg/10 E+8), with apositive correlation (r = 0.42) between these two values; in particular the authors attributed thealteration in the immune response to the tumor, especially of the phagocytosis, to the lowconcentration of vitamin C in the white blood corpuscles.Already in 1974 Goetz had shown that vitamin C, in vitro, was capable of stimulating the motilityand the chemiotaxis of neutrophiles.The doses advised in literature for anti-neoplastic therapy are about 3-10 grams a day, reachingeven 40 grams daily, because the vitamin is not toxic, at high doses it only has a laxative effect.It would be better to take it by eating fresh fruit, but it is difficult to reach such high doses of thevitamin in this way.According to the author, integrating fresh fruit (kiwi, oranges, lemons and grapefruit) with the juiceof raw carrots and tomatoes, Rosa canina (dog rose, wild rose) to reach a daily dosage of at least 5-8 grams of natural vitamin C, avoiding however, the use of pharmaceutically prepared vitamin Ctablets.Natural vitamin C, rich in its metabolites and other components called bioflavenoids (Citrin,Hesperidin, Campherol, Galangine, Isoamnetin, Rutine, Hyperoxide, Quercitin, Pychnogenol, etc)101

is more powerful and efficient, and furthermore is devoid of unpleasant gastric effects which are theresult of high doses of synthetic vitamin C.Natural vitamin C is moreover, characterized by a significant reduction in the formation of Calciumoxalate in the kidneys, as opposed to synthetic vitamin C. It is also easier for the intestine to absorband has greater bio-availability, above all through its most important metabolites such as tronicacid, lixonic acid, xilonic acid etc.This bio-availability has a critical importance in the immune defense system because the whiteblood cells tend to absorb Natural vitamin C 4 times more than they absorb synthetic vitamin C.Recently, Myrciaria paraensis (camu-camu) has appeared on the European market. It is a smallexotic fruit, similar to a small orange, but it contains 50 times more natural vitamin C than Citrusaurantium (orange), and it could therefore provide the daily dosage, of at least 3 grams, of vitaminC.Also Malpighia punicifolia (acerola), a cherry from the Antilles, is very rich in vitamin C,containing 50 to 100 times more than citrus fruits.Natural vitamin C is therefore efficient because it is naturally associated to the bioflavenoids(Citrin, Hesperidin, Campherol, Galangine, Isoamnetin, Rutine, Hyperoxide, Quercetine,Quercitine, Pychnogenol, etc..) and other molecules, in plants often characterized by an immunestimulating activity (Echinacea purpurea, Plantago major, Capsicum frutescens)...N.B. According to the author, with very high therapeutic doses (>8-10 grams a day), Magnesium(e.g. Dolomite) must also be taken to avoid the risk of kidney stones.Here enclosed scientific papers extracted from Catherine Kousmine (“Save your body”, page 129,“Effects of C vitamin on our body according to Linus Pauling, edition Tecniche Nuove):“…an intake of 1500 milligrams of ascorbic acid by mouth determines a concentration of 1.5 milligrams of C vitaminfor each 100 millilitres of blood. By increasing the intake, the concentration suddenly increases up to 2.5 milligrams andthen goes back to 1.5 millilitres for each 100 millilitres blood. There are enzymes which help the conversion of mostascorbates into useful oxidation products. If the intake remains high, the body increases the amount of enzymes usefulto the conversion; otherwise, if the ascorbic acid dose is suddenly reduced for some days, an excess of conversionenzymes and then a too law level of vitamin C in the blood occur. This means a number of disorders, as for example ahigher sensibility to infections. The adaptation to a lower proportion takes place by reducing the number of conversionenzymes: it is necessary to gradually decrease the dose of vitamin C. By taking 100 milligrams a day and in presence ofa plasmatic level of 1 milligram for every 100 millilitres blood, urines do not contain ascorbic acid because it isreabsorbed by renal tubules. If the intake is higher than 100 milligrams, i.e. 1-2 grams a day, 25% go in urines and therest is kept by the body. Healthy people, who lack in vitamin C for some months, have to take 2-4 grams in order toeliminate them through urines. In case of cancer patients, who are used to take high doses of ascorbic acid, aninterruption of some days requires an intake of 50 grams (fifty grams) of vitamin C so that this one can be found inurines”.102

Chapter 3.d: Vitamin DThere is a good bibliography on the anti-tumoral action of vitamin D ( 28,157,160,188,208,209,231,240,246,254,302,323,479,489 )Natural vitamin D, contained in some plants, is however preferable to the synthetic type, becausethe latter is about 10 times more capable of binding with Magnesium, taking it away from theorganism, thus causing all the damage that the loss of this incurs (osteoporosis, kidney stones).Vitamin D induces the inhibition of neoplastic cellular growth: this has been shown in vitro inneoplastic cellular lines; especially of the hematopoietic system, of the CNS, of the prostate; thecolon, the ovaries and the breasts.This action is thought to be expressed at various levels, in particular:a) by means of apoptosis induction, through the activation of p21, that is, the inhibitor of thekinase proteins;b) the inhibition of neoplastic cellular growth, which would be blocked in the G1 phase because ofthe action of the IGF1 inhibitor;c) by means of cellular differentiation.Vitamin D conversion factorsVitamin D is expressed in Calciferol micrograms1 microgram of Calciferol is equal to 40 I.U. of vitamin D.103

Chapter 3.e: Vitamin E (alpha-Tocopherol)There is also an extensive bibliography on the anti-tumoral action of vitamin E ( 6,19,20,30,45,91,95,112,125,129,142,165,167,190,202,228,229,246,261,280,332,404,405,452,494 )This liposoluble substance consists of a group of various components, called Tocopherols. Seven ofthese exist in nature; alpha, beta, gamma, delta, epsilon, zeta and eta.Alpha-Tocopherol has an anti-oxidant effect on the lipidic membranes in synergy with Melatonine,carrying out a preventative action on the peroxidization of the cellular membrane induced byionizing radiation and by chemical carcinogenes.Vitamin E also carries out an anti-oxidative action in a wider sense, acting as a 'scavenger' of thefree radicals, similar to vitamin C.It performs a stimulating activity on the immune system; it induces cellular differentiation; itinhibits, in a selective way, cellular growth intervening at DNA and RNA synthesis level.Various studies have shown its ability to induce apoptosis in cellular lines of breast carcinomas andlymphoma B.It is inactivated by Iron, therefore it is essential that any medicines based on Iron are not taken at thesame time as vitamin E, but at a distance of at least 10-12 hours.Aluminum, which is often present in pharmaceutical products, also deactivates vitamin E.The uncooked oil of Triticum sativum (wheat germ; note: has vitamin B12) contains about twice asmuch vitamin E as the uncooked oil from the seeds of Helianthus annuus (sunflower) and the lattercontains about five times as much as uncooked olive oil. Furthermore all these seeds are rich inessential unsaturated fats, an important part of the diet for cancer patients.In anti-neoplastic therapy much is being discussed about: the raw seeds of Helianthus annuus(which the author personally considers useful in therapy), wheat shoots (the author is not in favor),Saccharomyces cerevisiae (yeast, of which the author is not in favor), and the shoots of soyalecithin (of dubious use and the author is against their use because of the transgenic risk).The use of synthetic vitamins to supplement natural vitamins in oncologic therapy is still acontroversial issue. The author maintains, however, that the natural vitamins are by far preferable toindustrially produced ones: Dracontium loretense, for example, which is considered one of the bestplants for its specific anti-oxidant potential, is of superior quality in its anti-oxidant abilitycompared to synthetic vitamin E ( 566 ).As an already extracted natural product, together with or without other vitamins, vitamin E must begiven in addition to high quantities of raw seeds of Helianthus annuus (also containing vitamin A,all the vitamin B compounds, vitamin D, Manganese, Zinc and Magnesium) and of high quantitiesof raw Triticum sativum (which is rich in the precious alpha-lipoic acid): both are also very rich invitamin B6 (pyridoxin), the latter is important for the immune system, but it is difficult to find inother compatible foods for a suitable diet for cancer patients. Pyridoxin, in fact, is containedespecially in Saccharomyces cerevisiae, the latter is a food which the author does not regardfavorably for an anti-neoplastic diet, because it contains high quantities of folic acid.Natural Octacosanol, extracted from the oil of Triticum sativum, has a synergetic action withvitamin E, but it is, in any case, better to consume it with all the uncooked oil of Triticum sativumand/or Triticum sativum itself rather than taking it already extracted, as a pharmaceutical product(because it loses its active principles).Vitamin E is particularly efficient in combination with Selenium, which is contained in Aloespecies, Solanum lycopersicum (tomatoes), Equisetum species, Allium cepa (onions).There is also an extensive bibliography on Selenium( 79,108,112,129,133,136,143,156,228,229,276,338,339,364,367,404,405,407,443,452,458,501,510,511 )Both vitamin E and Selenium are in their turn synergetic with Zinc in inhibiting the production ofinflammatory prostoglandins and leukotrienes.104

Vitamin E conversion factorsVitamin E is expressed in milligrams of tocopheral equivalents (T.E.)1 milligram of Tocopherol is equal to:= 1 milligram of D-alpha Tocopherol= 2 milligrams of D-beta Tocopherol= 5 milligrams of D-gamma TocopherolGMO multinationals are modifying the contents of TocopherolsNowadays, the different amounts of Tocopherols contained in the plants are being deliberatelymodified. For example, scientific papers published the first researches on modification of Soyaseeds and other plants, such as Maize and Rice, which have the aim to reduce delta-Tocopherolfrom 20% to less than 2% and to increase alpha-Tocopherol up to more than 95% ( 1388 ). Although itis known that alpha-tocopherol is very important for the human health (250 milligrams areequivalent to 400 I.U. of vitamin E), some people arrogated to themselves the right to dramaticallyreduce the amounts of delta-tocopherol and beta-tocopherol in Soya, Maize and Rice ( 1388 ),considering them useless for human health and without taking into consideration the medical data,which demonstrated the importance of all tocopherols in the human diet (alfa, beta, gamma, delta,epsilon, theta). Since these vitamin E subgroups have a varied tissue distribution, the presence ofthese lipid antioxidants in the different mammalian biological tissues is probably guaranteed bydifferent mechanisms ( 1411, 1412 ).Furthermore, the plants themselves absolutely need their own tocopherols in order to surviveoxidative stress of both ultraviolet rays and sunlight. Scientific papers demonstrated that thethylakoid membrane –bound ascorbate peroxidase (t-APX) is a limiting factor in the antioxidantsystem of all chloroplasts under the oxidative stress induced by ultraviolet rays ( 1389 ). It wasdemonstrated that GMO potatoes lacking in this substance die in short time because of the effects ofultraviolet rays. So, as also demonstrated by another study ( 1390 ), the t-APX depends on thetocopherols. The German research shows that the reduction of Tocopherols contained in theThylakoid membrane is a limiting factor for the plant defence reaction against the oxidative stress.Furthermore, it was proved that the enzyme geranylgeranyl reductase (ChlP) is the most sensiblesystem to the light stress: its reduction in GMO plants is accompanied by a reduction of tocopherolsand chlorophyll. Therefore, Tocopherols are essential because they allow plants to perform theirnormal functions without being damaged by photo-oxidative stress (light). In particular, all 4 maintocopherols are essential to plants. A poor production of all 4 main tocopherols has devastatingeffects on GMO plants, as well demonstrated in case of tested GMO potatoes ( 1391 ). Finally, it wasdemonstrated that biological damage observed both in case of GMO Maize and GMO potatoes wascaused by a genetic mutation which brought about the loss of the four above mentioned tocopherols.105

Chapter 3.f: vitamin F(Partially extracted from “Catherine Kousmine: “Salvate il vostro corpo”, Tecniche Nuove, second edition pages 223-233)“Vitamins of group F are substances – i.e. polyunsaturated fatty acids – which have two or three bond double valencesand are defined as “essential” because they are essential to the body. But this one is not able to synthesize themnaturally. They are linoleic or linolenic acids, of a number of isomers exist. This group also includes arachidonic acid,which has four double valence bonds and plays a very important role in the brain functioning and structures. Humanbody can obtain it from the linoleic acid, which can be taken only by eating some particular foods.The linoleic acid becomes integrated with the membrane structures assuring them a normal permeability. It is the rawmaterial for the synthesis of other polyunsaturated fatty acids, as well of prostaglandins, lecithins, myelin, nervesheaths, etc. and plays a crucial role for the immune equilibrium.Therefore, biologically active vitamins F are of extreme importance and all developed societies are affected bydeficiency in these vitamins. Daily requirement of vitamin F was calculated to be 10-20 grams (contained for examplein one or two and a half spoons of cold-pressed sunflower oil), which is usually not fulfilled (Schweigart).Polyunsaturated fatty acids concentrate in sunflower seeds, linseeds, sesame, cottonseeds, poppy-seeds, sundrops, etc.,which contain great amounts. So the oil obtained from their seeds contains only a percentage ranging from 2% to 8%.Grass is rich in vitamin F but, although a cow daily consumes about 300 grams, bacteria contained in the animal rumendestruct a great part of it. So cow milk results to be three times poorer in these vitamins compared to the mother’s milk.After the Second World War, around the ‘50s, a certain number of apparently different diseases affected younger andyounger people more and more frequently (autoimmune diseases, cancers, allergies…).During those years a rather abnormal situation arose: on the one hand the permanent currency depreciation had causedan increase of the price of foodstuffs, on the other hand the price of oils was reduced. Naturally, nobody wondered whythis happened. This decrease in oil price was a positive factor for the family budget.But what really happened? During the war, foodstuffs were rationed because the supply of food with a right calorificvalue – above all that of fats – was insufficient. In order to increase the supply of fatty substances and to put them intothe market, some technicians carried out the hot-extraction of greater amounts of oil from the available oil seeds (attemperatures ranging from 160° to 200° C). So the oil obtained was refined and it lost its original flavour and taste; itresulted to be extremely practical, unalterable and heat-stable, chemically unchangeable under the effects of heating, airoxygen and light. These factors usually adulterate the cold-pressed oil, thus making it rancid. Since the yield doubled,the price went down.People usually consider oil as accessory food which supplies calories and then energy through burning inside the body.However, ongoing scientific progress is more and more worried about the catastrophic consequences of such anevolution for our health. Polyunsaturated fatty acids are fragile substances which easily turn into more stable isomers atparticularly high temperatures, during the extraction or food preparation. There are some anomalous intestinal bacteriawhich can cause this transformation. Cis-cis COOH groups- which are biologically active- become completely inactivecis-trans COOH groups in the above mentioned particular conditions, through the molecular fragments rotation at thelevel of double bonds (H. Sinclair).Linoleic cis-cis natural acid (vitamin F1) performs numerous functions in our body. It becomes part of the cellmembranes and it assures them the normal impermeability, thus protecting our body from attacks of external world. Adeficiency in vitamin F causes a loss of water through evaporation which immediately determines a raging thirst. Thistype of phenomenon can be easily demonstrated in rats. If a rat with nutrition deficiency is put under a bell glass, thisone immediately steams up, which does not take place if the rat is properly fed. Children lacking in vitamin F are reallythirsty, they suck damp cloths and continuously drink tap water. Through an intake of vitamin F, the situation gets backto normal.The deficiency in vitamin F manifests itself in school age children thorough common infections which tend to berecurring or chronic. A healthy and naturally fed organism is absolutely able to get over these infections, such asrecurrent colds, permanent sinusitises (both in winter and in summer), allergies of the skin (eczema, urticaria) or ofrespiratory tract (hay cold, bronchial asthma), which usually affect different organs. In order to treat these infectionstraditional medicine resorts to antibiotics, antihistamines and cortisone, which bring temporary relief without solvingthe real cause.Another warning signal is given by the skin, which undergoes a change; the deficiency in vitamin F – biologicallyactive – makes the skin very dry, beginning from feet, legs and then to all body. The skin becomes rough and flakes offin particles so small as to seem flour and when the woman takes off her nylon stockings, she is literally enveloped in a“dust” cloud. These signs and clinical symptoms are steady in my patients affected by severe diseases. Their skin seemsto be 10 or even 20 years older.106

Therefore, I suggest that you check the condition of your skin, which has to be smooth and silky, soft to the feel, ashealthy skins, regardless of the age. If you notice that your skin easily flakes off or is wrinkled, it means that somethingdoes not work properly. You should know that Nature sends you a precious warning: your body is not satisfied of howyou treat it. Clearly, you nourish the skin with unnecessary fatty substances (maybe artificial) or with oils containinginactive vitamin F or with oils naturally lacking in it. You should eliminate these inappropriate substances by replacingthem with cold-pressed sunlight oil, which is rich in vitamin F. This one should be used to prepare salads, wholemealcereal soups or steamed and then mashed potatoes; in short time, your skin will be normal again, as well your digestivemucosa, which is really important because of its extension and its numerous functions. If the digestive mucosa is notproperly stretched, it covers a surface of 40 m2, otherwise if it is correctly stretched – including its smallest folds andvillosities – can cover a total surface from 400 to 600 m2. It is an extraordinary thin mucosa, which is coated with asingle cellular layer usually of 2 hundredth of millimetre; since it is very fragile, it reforms completely every 2 days.Being very similar to the skin, it easily flakes off and therefore a sufficient amount of vitamin F should be taken.Otherwise, it becomes too permeable and protects no longer from toxic substances periodically present in the intestinalcavities. If these substances are too many, they can be no more neutralized by the liver and the ganglion lymphaticums,thus poisoning the body. The first symptom of such a severe alteration is diffused and persistent fatigue, which can beseen as a prelude to different chronic diseases affecting more than one third of the population, i.e. cancer, evolutionarychronic polyarthritis, sclerose en plaques or another autoimmune diseases, according to constitution of people.If the deficiency in vitamin F is chronic, vascular diseases (arteriosclerosis, phlebitis and thrombosis, myocardialinfarction), chronic hepatic and digestive disorders (diarrhoea or more frequently costiveness), a lowering of the bodyresistance to viruses and bacteria, tumours, etc. can appear.The cholesterol – precious raw material from which the body synthesizes vitamin D, sex and adrenal hormones, formsvery soluble Salts with polyunsaturated fatty acids. In the absence of polyunsaturated fatty acids, the cholesterol tiesitself with saturated fatty acids, thus forming little soluble salts which create yellow deposits in the skin, vessels andmucosas (xanthelasmas) and calculuses in the biliary vesicle. This happens very often in people consuming excessiveamounts of fats and fewer oils.Vitamin F performs another essential function: acting as raw material for the production of prostaglandins, which areimportant vital substances regulating the metabolism of each cell. Prostaglandins (whose etymological derivation is notcorrect because the prostate contains very few of them) are biologically active and important substances, present in eachcell and originated from polyunsaturated fatty acids. They were isolated by von Euler in 1935 and nowadays some ofthem can be synthesized. They regulate the metabolism and are released from phospholipids of cell membranes, whichincorporate their precursors.Nowadays, 14 prostaglandins are known. They are originated from unsaturated fatty acids, whose chain centre, between9 and 13 carbons, forms a ring of 5 carbon atoms. They differ from each other in the number and the position of thedoubled bonds (2-5) and of some rare O and OH groups on the chain.The discover of prostaglandins allowed to understand numerous symptoms due to a lack of vitamin F, their lowspecificity, the extraordinary health improvements obtained through the replacement of saturated fats with cold-pressedunsaturated oils. I said “replacement” and not “addition” not at random, because in case of food containing too manysaturated fatty substances, such as butter, the intake of vitamin F causes only a slight improvement, sometimes useless.Every kind of alteration of the cell membrane causes the release of prostaglandins, which provide local protection andnourishment and regulate the penetration of hormones – which are put into the bloodstream by endocrine glands- intothe cells (according to their needs). They were defined as “cell hormones” because they play a significant role inregulating intercellular chemical processes.Prostaglandins are active already in presence of an amount of a milligram thousandth. Even a minimum alteration oftheir structure can modify their action, which is different in the various organs and animal species and can be reversed.Locally they are very active and once introduced in the plasma they live 1-3 minutes on average, after that half of thembecome inactive; they are produced very fast and die soon; for this reason are not used much in the pharmaceuticalsector.The following is an example of prostaglandin PGE1 activity: an abnormal blood clot, known as thrombus, can form in avessel if firstly the cells, called platelet, agglutinate. PGE1 prevents this agglutination. Nowadays thrombosis (orformation of a thrombus) is considered as a very frequent – and sometimes dangerous – postoperative complication,because the clot can move and then obstruct vital vessels (embolism). This kind of disorder could be caused by a lack ofPGE1 due to a deficiency in biologically active polyunsaturated fatty acids. In order to prevent thrombosis,anticoagulant drugs are usually prescribed, but they can provoke severe haemorrhages. Therefore, it is always necessaryto keep under medical control the blood circulation. At the experimental stage, it was demonstrated that in micethrombosis can be prevented with a diet rich in linoleic acid or the intake of PGE1 (Owien, Hellem e Odegaard).At the experimental stage, increasing the amount of linoleic acid in the diet (2 millilitres linseed oil every day) allowedto lower the platelet adhesiveness, thus avoiding thrombosis. Consequently, the type of fatty substances cansignificantly contribute to the outbreak of similar diseases. During more than 30 years of profession, among mypatients, whose diet had been corrected for more than two months by decreasing saturated fatty substances and adding107

cold-pressed oils rich in vitamin F, there were no cases of postoperative thrombosis without resorting to anticoagulants.As said before, prostaglandin – which prevents thrombosis – originates from linoleic acid; but there is one type ofprostaglandin deriving from arachidonic acid with the opposite function. If it is not impossible to prevent a coagulationin a vessel, however in case of haemorrhage it is necessary to cause the aggregation of thrombocytes, thus allowing theformation of the blood clot. In order to do that, prostaglandin PGE2 is used.Prostaglandin biological activities are various and numerous: they regulate the activity of the smooth musculature andglands; they activate the water and electrolyte secretion in the intestine by stimulating its motility; but if they areproduced in excessive amounts they can cause diarrhoea; they stimulate the secretion of adrenal hormones (aldosteroneand cortisone) influencing the activity of the hypophysis and affecting the metabolism regulation of water and mineralsalts. It was supposed that the arterial hypertension originates from a deficiency in prostaglandin. A nerve stimulus isdue to the prostaglandins produced by brain and spinal marrow. The spinal marrow contributes to the transmission ofthe nerve impulse. Prostaglandins are also necessary for the procreation as they help the spermatozoon to enter theovule; the sperm is normally rich in prostaglandins and has 13 different species of them. It was noticed a lack ofprostaglandins in 8% of male sterility cases. Furthermore, it was supposed that during the childbirth contractions arecaused by a release of prostaglandins, which are more numerous in amniotic fluid in that particular moment. Whereasduring menstrual periods, the amount of these substances increases in the blood circulation.Taking prostaglandins can cause violent inflammations with high temperature.Anti-inflammatory drugs, such as the Aspirin, stop the synthesis of some prostaglandins and influence negatively theactivity of the others, by opposing to the stimulating effects on the sensible pain receptors (PGE2). Some tests carriedout on rats demonstrated that taking prostaglandins prevents the gastric ulcer caused by high doses of cortisone. I cansay that patients with a high percentage of linoleic acid never had this kind of complication, despite cortisone treatmentsover an extended period of time.By increasing or decreasing intercellular metabolic processes and by regulating intercellular nucleotide synthesis (AMPand cyclic GMPs), prostaglandins play a significant role in the processes of biological regulation performing differentand specific functions in the various mechanisms of cell self-defence. A prostaglandin insufficient production, causedby an insufficient intake of raw material allowing the synthesis, determines a lowering of vital resistance and disordersof different origin, in particular those affecting the body immunity.Currently, the common diet is really deficient in biologically active linoleic acid, i.e. the raw material of prostaglandins.In particular in the European countries it is too rich in calories, 30%-45% of which derive from saturated animal fats. Inmen vitamin F requirement is significantly increased, being proportional to the amounts of calories and fatty substancesconsumed. A normal subject reacts to the intake of fatty substances with an overproduction of lecithin and an increaseof this one in the blood and in the bile. Moreover, each molecule of lecithin includes one or two polyunsaturated fattyacids.Some people hope that synthesis of longer-living prostaglandin could treat the different diseases in a more effective and“natural” way. We could ask ourselves whether Nature gave these extraordinary regulators such a great variety, shortlife and numerous cell functions in order to fulfil specific needs and whether the synthesis of longer-living synthesisedsubstances involving all cells – both cells which need it and cells which do not – would not cause a number of unwantedside effects.Isn’t so more reasonable and then wiser supplying a proper intake of raw material in the form of natural linoleic acid,allowing it to perform directly such a delicate synthesis?As above underlined, there are two types of prostaglandins: one is known as PGE1, which derives from cis-cis linoleicacid and has anti-inflammatory properties, the other one is known as PGE2, which derives from arachidonic acid andcontributes to the inflammatory processes.Our health needs a perfect equilibrium between these two prostaglandins. Recent studies demonstrated that cis-cislinoleic acid has to undergo different chemical modifications to become PGE1. The first modification regards theproduction of gamma-linoleic fatty acid. In the first stage the linoleic acid molecule gained an extra double valence,passing from two to three. It is a very difficult chemical transformation, which absolutely needs a specific enzyme(delta-6-desaturase), vitamin B6, Magnesium, Zinc and vitamin B3. The following transformations into di-homogammalinolenic acid with 20 carbon atoms (helped by vitamin C) and then into PGE1 prostaglandin take place moreeasily.If the first reaction occurs in advanced age, it takes place with some difficulties, determining malaise and fatigue and insome cases actual diseases. Similar alterations can take place also when one is young, if the body lacks in cis-cislinoleic acid, i.e. the raw material essential to the prostaglandin production; moreover, using more and more industrialfatty substances can determine these alterations. In nature linoleic acid exists only in the form of cis-cis; its isomer, i.e.cis-trans-linoleic acid, is produced by man. Currently, fatty substances, which are on the market and are manipulated byindustries, contain no longer the cis-cis group, which was replaced by cis-trans group. This one is not able to transforminto PGE1 and blocks the present cis-cis group, thus increasing its deficiency.The above mentioned alterations or disorders can also occur because of a lack of the transformation enzyme (delta-6-desaturase), or vitamin B6, Magnesium or Zinc.In this way, a deficiency in B6 vitamin can cause diseases similar to those caused by a lack of vitamin F.Once gamma-linoleic acid is produced, the different transformations can take place, thus producing di-homo-gammalinolenicacid, and then PGE1, in presence of vitamin C and vitamin B3.108

It could be useful to give doses of prepared gamma-linoleic acid – which is very rare in nature – to old people or peoplesuffering from particular diseases (for example, ectopics). It is possible to obtain it from the seeds of two plants:Oenothera biennis and Borrago officinalis.Oenothera biennis seeds oil contains 7-9% of gamma-linoleic acid, whereas Borrago officinalis seeds oil contains 23%.The capability of body cells to produce prostaglandin PGE1 in a normal way and according to the needs is an essentialfactor for our body equilibrium and health because the PGE1 regulates the normal functioning of the immune systems,which otherwise are insufficient and aberrant. PGE1 prevents every kind of pathologic inflammation physiologically. Incase of an excess of PGE2prostaglandin, which contributes to inflammatory processes and results to be dangerous,corticosteroids and anti-inflammatory drugs stop the overproduction; unfortunately, these drugs stop at the same timePGE1 production, making the recovery impossible.That’s why they have to be considered as simple palliatives.PGE1 controls the blood circulation, prevents arterial hypertension, heart disorders and arteriosclerosis.Coronary diseases alarmingly increased during this century. This is due to the development of techniques of foodcultivation, refining and preservation, which impoverish our diet by eliminating Magnesium, vitamins B6, F and E. Thegreater consume of fatty substances and the use of vegetable fats, such as Margarine or hot-pressed and refined oils,gave epidemic proportions to these diseases, which affect also young people. Carcinogenic cells abundantly producePGE2 but not PGE1; in cell cultures, human cells can become malignant through irradiation or carcinogenic chemicalsubstances, losing their capability to transform cis-cis linoleic acid into gamma-linoleic acid and to form PGE1.In case of a patient affected by cancer, it is very useful to take gamma-linoleic acid. This one strengthens the beneficialaction of vitamin C.There are different defence lines of our body against carcinogenic toxic substances: the first one is the intestinalmucosa, the second one is the liver and the third one is the cell membrane, which protects the cell itself from thepenetration of carcinogenic toxic agents.PGE1 prostaglandin is the most powerful defence agent against cancer. Recently, it has been discovered a prostaglandinwhich derives from gamma-linoleic acid and is able to stimulate immune system’s T lymphocytes.Vitamin F – biologically active – is therefore extremely important for our body; we know that it is found in all oil seedsand in cold-pressed oils, above all in sunflower, linseed and wheat germ oils, which do not require added solvents.Nut oil has to be heated to at least 40° C, which should not endanger the presence of vitamin F but remains a risk factor.Olive oil is instead poor in vitamin F (2-8%), whereas the other oils are richer (50-70%). Safflower seeds, which arevery hardy, have to be pressed more strongly, at a temperature ranging from 58° to 60° C during the oil extraction. Thistemperature range represents the limit above which the biological properties of vitamin F disappear.Beneficial effects of Oenothera biennis oil are numerous and polyvalent: it alleviates premenstrual pains and regulatesmenstrual periods; if associated with Zinc, it can be effective against acne; finally, it has positive effects in case ofSjögren syndrome. Behind the nape and along vertebral column, our body has a special fatty brown tissue, whose cellsare particularly rich in mitochondria and produce heat. Moreover, by protecting from cold and through an internalcombustion, these cells destroy excess calories. If the individual is obese, this tissue does not work properly, but anintake of gamma-linoleic acid stimulates through prostaglandins the mitochondria of fatty tissue, determining a gradualnormalization of the weight without resorting to severe diets.It was observed that patients with diabetes – who follow a diet rich in polyunsaturated acids – suffer from fewer eye andheart complications.The two functions of cis-cis linoleic acid are different and equally necessary for the human health: it guarantees thenormal permeability of cell membranes and tegumentary tissues; on the other side, it is the raw material for theproduction of PGE1.Gamma-linoleic acid – which is the precursory of PGE1 and originates from cis-cis linoleic acid – cannot replace cis-cislinoleic acid in the performing the first above mentioned function; the following case clearly demonstrates it.Note of the author (Doctor Giuseppe Nacci):Vitamin F could make cell walls more permeable to vitamins, equally to what is supposed in case of glucose in order toprevent diabetes.Basically, it is supposed that the low percentage of people suffering from cancer before the Second World War –together with the low percentage of diabetic patients – could be correlated to the limited presence of saturated fattyacids in the diet and to the great availability of polyunsaturated fatty acids contained in cold-pressed oils.Nowadays, however, the reintroduction of cold-pressed linseed or sunflower oils is NOT a sufficient sign of foodsafety. Unfortunately, the introduction of cultivations of GMO flax (Genetically Modified Organism) in the opencountry of the USA, even close to the border of Canada (the major world producer of biological linseed cold-pressedoil), represents severe and unjustified obstacles and damage to this therapy, not only with regard to diabetes and cancerstreatments, but also to other chronic-degenerative diseases.109

Chap. 3.g : Organic Germanium Ge 132107, 110, 119, 139, 174, 193, 237, 249, 269, 336, 357, 386, 399, 440,There is an ample bibliography about this substance (441, 460, 476 ). SEE in PDF: Mainwaring MG: Complete remission of pulmonary spindle cell carcinoma aftertreatment with oral germanium sesquioxide, Chest, 117, pp. 591-593, 2000; Chest, 117, pp. 307-308, 2000http://www.erbeofficinali.org/dati/nacci/studi/Germanium%20132%20un%20caso%20clinico%20di%20cancro%20polmonare.pdfOrganic and inorganic forms of GermaniumIn its inorganic from Germanium is present in the soil, rocks and coal, together with other mineralsfrom which it can be extracted and transformed industrially into organic Germanium. For anytherapy, only very pure organic Germanium should be used. The heavy metals (Pb, As, Hg, Cd)should be almost absent, and if they are present should only be in well defined and negligiblequantities (

or caused by some deficiency. In particular, its biochemical characteristic is that it acts as a semiconductorin the transport processes of the electrons inside the cells, thus allowing the formation ofATP with the final production of non toxic molecular substances (water). Its anti-oxidant actionagainst cysteine is also important.Cell respiration refers to the catabolic processes by means of which the nutritive substances,glucose for example, are broken up inside the cells, releasing energy which is then used to formAdenosine-Tri-Phosphate (ATP, cell energy). With organic Germanium an exothermic reactiontakes place, which supplies oxygen and hydrogen to the individual cells of the organism. The stableand continuous flow of oxygen and hydrogen to all parts of the organism facilitates and strengthensoxidation and reduction inside the cells: oxidation takes place either with the acquisition of oxygenor with the loss of hydrogen.Any reaction which creates energy inside a cell is an oxidant reaction.Oxidation can happen in two ways:1) the combination of oxygen with other elements2) the removal of hydrogen atoms from the compounds.Basically, oxidation of nutritive substances is the gradual removal of pairs of hydrogen atoms fromthe support molecules, because when the pairs of hydrogen atoms are removed, they take with themtheir electron pairs. In this way oxidation of glucose in Krebs’ cycle occurs with the gradualremoval of hydrogen atoms.Where a substance loses electrons, becoming oxidated and losing energy, there is another substancewhich acquires them, thus becoming reduced, that is to say, acquiring energy.The hydrogen atoms which are removed are sent to the electron transport chain, which converts theenergy taken from the oxygen, to transport the electrons along the whole length of the chain.In the end the hydrogen atoms which are removed combine with the molecular oxygen (creatingwater), and the resulting energy is freed as ATP, and thus available for the cells.The immune cells, such as the very delicate lymphocytes, thus acquire an energy capacity whichenables them to do their work even in a hypoxic environment such as cancer tissue, famouslycharacterized by High Interstitial Fluid Pressure (H.-I.F.P. see: see: Jain R.K.: Barrier to Drug Deliveryin Solid Tumors, Scientific American, Science, July,1994). Vice versa the cancer cells, which have becomeoxidated both because of the removal of hydrogen and also by the endocell molecular reaction withoxygen, both induced by the presence of organic Germanium, as a result are more exposed to thephenomena of apoptosis and pseudo-apoptosis, being poor in enzymatic complexes which wouldperform an endo-nuclear repair of their own DNA, which on the contrary are characteristic ofnormal cells which have not been degenerated by cancer.Anti-ischemic properties of organic GermaniumIt acts as an electro-nutrient in hypoxic states, which are frequent in chronic degenerativepathologies, such as cardio-vascular or neuro-vascular pathologies or those of the metabolism ingeneral. Organic Germanium stimulates the ability to increase the availability of oxygen for thecells and helps eliminate unpaired electrons. This makes it particularly invaluable in cases of acuteischemia (miocardic infarct, strokes and asphyxiation by carbon monoxide).111

Modifications of the biochemical and functional parameters of the organisminduced by organic GermaniumThe catalytic effects on the use of oxygen are seen in the renormalization of the biochemical andfunctional parameters of the organism in a time-frame of between 4 to 6 weeks:1) Regularization of the partial pressure of carbon dioxide in the blood.2) Regularization of the values of hematic glucose, above all in diabetic patients.3) Reduction of the triglycerides.4) Regularization of total cholesterol with an increase in the ratio of HDL/LDL.5) Normalization of bilirubin.6) Normalization of uric acid.7) Regularization Na / K, Ca / Mg.8) Increase in haemoglobin.9) Lymphocite rebalance in chronic infectious diseases. (HIV/AIDS).10) Protection from oxidative damage induced on the DNA by ionizing radiation.Anti-amyloidosis property of organic GermaniumAmyloidosis is often induced by Chemo-Therapy or radio-therapy. Germanium protects against theaccumulation of amyloid substances, a process which is generated by a protein imbalance in thecatabolism and often associated with chronic inflammatory conditions.Analgesic property of organic GermaniumOrganic Germanium has analgesic effects, acting as a neuro-modulator. This happens through theinhibition of enzymes (peptidase such as Aminopeptidase, Carboxypeptidase, dipeptidil-Aminopeptidase and dipeptidil-Carboxypeptidase [also known as Enkefalinase B and D]) whichdowngrade the endorphins.N.B.: since it is difficult to find natural organic Germanium, and it is very expensive, the followingproposal could be useful: to use inorganic Germanium (which is much less expensive than organicGermanium) in the cultivation of plants with a great capacity for trace-mineral uptake. According tothe author the cultivation of Equisetum arvense, Medicago sativa, Rosmarinus officinalis and Aloearborescens could be particularly useful.112

Chapter 3.h: Garlic (Allium sativum)From INTERNET: Herbal Therapies for Cancer, by Vivekan Don Flint and Michael Lerner, Research Assistance:Melanie Smith, October 1997.(NON reported in Italian version of commercial Book “Diventa Medico di te stesso !”)Traditionally, garlic has been used to control dysentery and parasites and for detoxification, feverand stomach aches.( 1075 )There is no data in the National Toxicity Program on garlic ( 1074 ), but the ancient Chinese classifiedgarlic as a moderately toxic herb because high doses can lead to stomach upset and intestinal gas( 1075 ). In 1983, Caporaso reported that the maximum tolerable dose of fresh aqueous garlic extractwas 25 ml and that greater amounts caused severe burning sensations in the esophagus and stomach,as well as vomiting ( 1076 ).In a review of the research on garlic by Judith Dausch and Daniel Nixon in a 1990 issue ofPreventive Medicine, they note that there have been hundreds of animal and human studies sincethe 1930s on the potential benefits of garlic or its active ingredients. Since the 1970s, most researchhas focused on its antibacterial activity, lipid-lowering effects, antiplatelet aggregation effects, drugmetabolizing properties and its anti-carcinogenic actions. They conclude that "evidence suggests apotential role for garlic or its components in several areas including prevention or control ofcardiovascular disorders, treatment of viral and fungal conditions and prevention and treatment ofcertain cancers."( 1075 ). According to a 1995 survey, garlic is the second most popular segment of theover the counter market for herbs ( 1077 ).As of September 1996, the Office of Alternative Medicine (OAM) had identified 250 citations inthe medical literature for garlic, of which 171 pertained to cancer. Of the 89 studies they reviewed,ten were carried out with human subjects, 61 were animal studies and ten were in vitro studies. Allof the human studies the OAM evaluated were studies of garlic as preventive for cancer and showedmixed results, with Chinese studies generally showing positive results for the cancers examined andWestern studies showing no association.It was first believed by researchers that the single beneficial element in garlic was allicin, thecompound formed when the bulb is crushed. Allicin is an unstable compound that is stronglyantibacterial and mainly responsible for garlic's characteristic odor. But in addition to allicin,researchers have discovered 32 other sulfur compounds in garlic, along with 17 amino acids,Germanium, Calcium, Selenium, Copper, Iron, Potassium, Magnesium, Zinc, and small amounts ofvitamins A, B1 and C. The main active components in garlic seem to be the various sulfurcompounds, including Allicin, Allixin, diallyl Disulfide, diallyl Trisulfide and thioallyl amino acids,as well as other compounds formed during cooking and food preparation.( 1075 )Dausch and Nixon report that, with regards to cancer research, the majority of human studies havebeen epidemiological in nature. Others have been in vitro or animals studies of the possible role ofgarlic in the prevention of cancer. According to Dausch and Nixon:One possible beneficial effect of garlic or its components may be their ability to enhance the body'smechanism for eliminating exogenous substances including carcinogens. In some studies garlic hasbeen shown to have a stimulating effect on certain enzymes that are known to be involved inremoving toxic substances. Antihepatotoxic [liver detoxifying] activity of garlic sulfur componentshave been described in vitro and vivo ( 1074 ).113

This capacity to enhance liver detoxification could potentially be of great interest to cancer patientswho are undergoing chemotherapy for cancer, since the it is the liver that functions to eliminate thetoxic chemotherapy from the body.Li and colleagues at the Strang-Cornell Cancer Research Laboratory describe the research on garlicin a 1995 article in Oncology Reports:...Based on experimental and epidemiological evidences garlic could be classified as an anticarcinogen.The specific phase(s) of the carcinogenic process, i.e., initiation, promotion, orprogression at which garlic or its constituents may exert its biological effect, however, remains tobe determined in many cases...Sources and mode of extraction of specific constituents from garlic showed an inhibitory effect onthe production of DNA adducts initiated by chemical carcinogens on mammary cell DNA.Postulates to explain the anti-carcinogenic effect of garlic constituents have been proposed andthese range from bio-inactivation of carcinogens, induction of free radical scavenging mechanisms,enhanced detoxification involving the glutathione pathway, and more recently, it has beensuggested the cancer cells may be growth arrested in the G1-G0 phase of the cell cycle...( 1078 )Describing their 1991 research on one of the active components of garlic, Maurya and Singhconclude:Diallyl sulfide [DAS], an organosulfur compound identified as the flavor component in garlic, hasbeen shown to inhibit chemically-induced neoplasia of forestomach and lung in mice. Even thoughthe exact mechanism(s) of anti-neoplastic activity of DAS is not known, several independent studiessuggest that this effect may, at least in part, be due to the elevation of glutathione-S-transferase[detoxification] activity ( 1079 ).Although most research with garlic and cancer has focused on prevention, intriguing evidence existsconcerning the potential for garlic as an adjunct to therapy for existing cancers. According to Boik,"theoretically, garlic may inhibit cancer by a variety of mechanisms, including reducedangiogenesis, reduced platelet aggregation, and increased fibrinolysis (discussed below)" ( 1180 ).Dutch researchers found that compounds in garlic inhibit endothelial umbilical cell proliferation invivo, an indication that they might also inhibit tumor angiogenic activity, which also involves therapid proliferation of endothelial cells.The antiangiogenic effect of thiols, compounds found in garlic, may be related to their ability toinhibit free-radical production by macrophages. Macrophages are found in great numbers in solidtumors, and can comprise 10 to 30 percent of the cells in a tumor. Under the low-oxygen conditionsfound in the interiors of solid tumors, macrophages secrete large amounts of angiogenesis factors,perhaps because of the stimuli are similar to those found in situations where wound healing isrequired ( 1182 ). According to Koch:We showed previously that thiol-containing compounds inhibited the production of macrophagemediatedangiogenic activity. Since thiol containing compounds may act on macrophages byaffecting activation and inhibiting the production of oxygen free-radicals, we studied the effects ofoxygen free-radical scavengers on production of angiogenic activity...We conclude that oxygenfree-radical scavengers are potent inhibitors of the production of macrophage-mediated angiogenicactivity ( 1083 ).Compounds found in garlic might also influence angiogenesis through their effects on the process114

of fibrinolysis, or the breaking down of fibrin. Fibrin is the protein material that comprises theessential portion of blood clots and is formed as a result of the process of inflammation. The areaaround tumors is commonly inflamed and a provisional stroma, or support structure, composed offibrin forms around the tumor. According to Boik, the formation of this fibrin stroma may be themost important single precondition for tumor angiogenesis to occur. Boik cites research showingthat the removal of this fibrin through the process of fibrinolysis terminates angiogenesis. He alsospeculates that by increasing fibrinolysis, the periphery of the tumor may be exposed to greaterimmune attack ( 1084 ).A number of human studies have been carried out on the fibrinolytic properties of garlic that mighthave a bearing on some forms of cardiovascular disease. Some of these studies also indicatepotential benefit to people with cancer.Italian researcher Legnani and colleagues found the following responses to garlic ingestion (900 mgdaily of dried powder) in a study of 12 healthy subjects in a randomized, double-blind, placebocontrolled study on fibrinolysis and platelet aggregation:Total euglobulin fibrinolytic activity...[was] significantly higher 4 and 6 hours aftergarlic...ingestion, and no differences were recorded between treatments. After 14 days of treatment,t-PA [tissue plasminogen activator, the principle mediator of fibrinolysis] activity was significantlyhigher after garlic...Platelet aggregation...was significantly inhibited 2 and 4 hours after garlicingestion; platelet aggregation values were also significantly lower after 7 and 14 days of garlictreatment ( 1085 ).Arora also assessed the fibrinolysis-enhancing properties of garlic in patients with ischemic heartdisease and in healthy control subjects. Though blood fibrinolytic activity was enhanced, the peakactivity occurred at the 4th week of garlic therapy but was not sustained despite its continuous useand returned to about the pre-garlic values at the 12th week. Garlic withdrawal did not cause anyfurther change in blood fibrinolytic activity ( 1086 ).Another study in humans, this one a placebo-controlled double-blind study by Kiesewetter andcolleagues, demonstrated a significant decrease in thrombocyte aggregation through theadministration of 800 mg of garlic daily powder over a period of four weeks. Plasma viscosity wasalso shown to decrease ( 1087 ). Both effects lessen the likelihood of tumor cell arrest at potentialmetastatic sites.Feng and colleagues found that diallyl trisulfide (DATS) at high levels had an inhibitory effect on Tcell activation, but at appropriate concentrations augmented the activation of T lymphocytes,immune cells that might play a role in the immune response to cancer. In addition:DATS can antagonize the inhibition of tumor-derived immunosuppressive factors produced byS180 cells and Ehrlich ascitic cancer cells on the activation of T cells, and reduce the inhibitory ratesignificantly...When macrophages were pretreated with DATS for 24 hours, the cytotoxicity ofmacrophages to three tumor cell lines was significantly higher than that in corresponding controlgroup...These results indicate that DATS can augment the activation of T cells and enhance the antitumorfunction of macrophages, suggesting that DATS may be potentially useful in tumor therapy( 1088 ).Evidence also exists of a direct anticancer effect with garlic. An in vitro study by Xie examined theeffect of garlic oil on the DNA content of the cancer cell cycle using flow cytometric analysis:115

This technique may measure DNA content of 5000 cells per second and traces the dynamic changesin the cell proliferation cycle and offers a hint for designing clinical treatment protocol, monitorprognosis and elucidate the mechanisms of antitumor drugs. The authors' previous studies showedsignificant effect of garlic oil on prolongation of life expectancy and inhibition of tumor growth inmice. Using FCM [flow cytometric analysis] the authors analyzed the effect of garlic oil on cellcycle in S180 tumor cells, 2-6 hours after single administration or multiple administration. Thenumber of cells in S phase rapidly decreased, in G1 phase increased. This suggests garlic oil mayblockade cells...progress from G1 phase to S phase and result in accumulation of cells in G1 phaseand directly inhibit the synthesis of DNA and the cell cycle ( 1089 ).A second study by Xie and colleagues on the effect of Kang ai-bao II on cancer cells using confocallaser scanning microscopy found that this garlic preparation had a destructive effect on DNA andRNA of cancer cells ( 1090 ).Dausch and Nixon describe a 1985 Chinese study by Xiyu that compared the cytoxic effects offresh garlic, diallyl trisulfide, 5-FU, mitomycin and cis-DDP on human gastric cancer cells in vitro.Mitomycin exerted the strongest effect, but fresh garlic also had a marked killing effect. Diallyltrisulfide was stronger than 5-FU against this gastric cell line ( 1091 ).Li and colleagues also demonstrated an antiproliferative effect with aged garlic (AGE) and two ofits allyl constituents in a human breast carcinoma model. They determined that "aged garlic extractdemonstrated substantial inhibitory effect on the cancer cell lines; these AGE treated cells hadsubstantially lowered growth rate than that of the cells treated with each compound alone"( 1092 ).In a 1993 study published in Oncology, Hiromitsu Takeyama and colleagues examined the effect ofan amino acid compound derived from garlic, S allyl cysteine, or SAC on nine human melanomacell line in vitro. They found that growth was inhibited in all melanoma cell lines, while it was notinhibited in three lymphoblastoid cell lines. The researchers also found that morphological changeswere induced in the melanoma cells by SAC and that the cells appeared more differentiated andpossibly had reverted to a less malignant state ( 1093 ).In another study examining the effect of garlic constituents on a melanoma cell line in culture,David Hoon and colleagues at the UCLA Medical Center found that an extract of aged garlicsignificantly inhibited the growth a the melanoma cells and "appeared to be a more potent or anequivalent inducer of differentiation of melanoma compared to some known cytokines andagents...The modulatory effect on cell growth and differentiation by [garlic extract] may havepotential benefit for prevention and control of melanoma progression in humans ( 1094 ).Similarly, in a 1993 study using canine mammary tumor cells in vitro, Sundaram and Milner foundthat three water soluble constituents of garlic did not significantly inhibit cell growth, while two oilsolublecompounds, diallyl sulfide and diallyl disulfide, did significantly inhibit growth and a third,diallyl trisulfide, resulted in cell death ( 1095 ).Dausch and Nixon also summarize numerous in vivo studies with mice demonstratingimmunomodulatory and anticancer effects:* In a 1964 study, Kimura and Yamamoto described the effects of garlic extracts on a transplantedascites sarcoma in rats. When injected interperitoneally, the extract inhibited tumor cellproliferation by producing irregularities in chromosomes during cell division ( 1096 );* In a 1967 study, Fujiwara and Natata found that when mice were injected twice at a seven-day116

interval with a suspension of Ehrlich ascites tumor cells pretreated with garlic extract, theydeveloped a strong immunity to the same type of tumor cells. They attributed this acquiredimmunity to the interaction of allicin with tumor cell proteins ( 1097 ).* In a 1973 study, Nakata treated a variety of tumor cell types in mice with fresh garlic extract.Tumor development was found to be reversed in mice injected with Ehrlich ascites tumor andYoshida sarcoma cells that were preincubated with garlic solution ( 1098 )* In a 1981 study, Cheng and Tung tested numerous compounds in Sarcoma 180 tumor-bearingmice and found that multiple intratumoral injections of allicin or allithiamine resulted in significanttumor inhibition ( 1099 );* In a 1981 study, Dhillon found a substance purified from garlic effective in inhibiting the growthof two Morris hepatomas in rats ( 1100 );* In a 1982 study, Criss compared the effectiveness in inhibiting Morris hepatoma 3924A in rats bydietary administration versus subcutaneous injection of garlic extract. Subcutaneous injectionlowered tumor growth by 30-50 percent compared to 10 to 25 percent by dietary administration( 1101 ) ;* In a 1983 study, Choy found a 42 to 59 percent inhibitory effect by the oral administration of agarlic suspension on the growth of Ehrlich ascites tumors in the peritoneal cavities of tumorinoculatedmice. Survival time was increased significantly by the administration of garlic ( 1102 );* In a 1986 study, Lau and Marsh studied the immunotherapy effects of garlic extract and otheragents on transplanted transitional cell carcinoma in mice. Intralesional administration was foundto be much more effective in inhibiting growth than the intraperitoneal route. Also, fiveintralesional treatments of garlic extract to the bladders of mice with transplanted transitional cellcarcinoma resulted in inhibition of tumor growth as well as the production of macrophages andlymphocytes, leading to the destruction of tumor cells. It was theorized the result was due toenhanced production of lymphokines, such as tumor necrosis factor, that could result in increasednatural killer cell activity ( 1103 ).In a follow-up study, Marsh confirmed that garlic administered intravesically (into the bladder) wasa more effective immunotherapy for transitional cell carcinoma than was BCG:Intravesical immunotherapy with bacillus Calmette-Guerin (BCG), Corynebacterium parvum (CP),keyhole limpet hemocyanin (KLH), and an extract of Allium sativum (AS) was studied in micetransplanted intravesically with mouse bladder tumor cells (MBT-2)...Immunotherapy with BCG (2X 10(6) CFU), CP (250 micrograms), KLH (50 micrograms), or AS (25 mg) was administereddirectly into the bladder via urethral catheter on day 1, day 6, or days 1 and 6. On day 21 thebladders and spleens were excised and weighed, and the bladders were examined macroscopicallyand microscopically for evidence of tumor. The results of the study showed that two treatmentsgiven one and six days after tumor transplant yielded the lowest tumor incidence and that CP andAS appeared equally effective or even slightly more effective than BCG in this model. These resultssuggest that clinical evaluation of CP or AS may be worthwhile ( 1104 ).The efficacy of garlic with bladder cancer in vivo was also evaluated by Donald Lamm at WestVirginia University using an extract of aged garlic. The researchers ranomized 72 mice into sixgroups and inoculated each with a transitional cell carcinoma line:117

Tumor incidence was significantly reduced in the groups which received AGE [aged garlicextract]...relative to Saline controls. All doses of AGE significantly reduced tumor volume whencompared to the Saline control. There was no statistical difference between the groupreceiving...garlic extract and the BCG control group. The highly beneficial reduction in tumorgrowth with AGE immunotherapy suggests that AGE will prove to be a highly effective form ofimmunotherapy for the treatment of transitional cell carcinoma of the bladder ( 1105 ).In an Indian study, Unnikrishnan and Kuttan examined the antitumor activity of extracts of eightcommonly used spices in India in mice transplanted intraperitoneally with Ehrlich ascites tumor:Oral administration of extracts of black pepper, asafoetida, pippali and garlic could increase thepercentage of life span in these mice by 64.7%, 52.9%, 47% and 41.1%, respectively...Garlicextract and asafoetida extracts also inhibited two stage chemical carcinogenesis induced by 7,12dimethyl benzanthracene and croton oil on mice skin with significant reduction in papillomaformation. These results indicate the potential use of spices as anti-cancer agents as well as antitumorpromoters ( 1106 ).Several studies indicate that garlic enhance the effectiveness of some chemotherapies or inhibit themutagenic effect of chemotherapeutic drugs on normal cells. Pan and colleagues in 1988 examinedthe cytotoxic effects of allyl trisulfide when combined with three chemotherapeutic agents on amoderately differentiated human gastric adenocarcinoma cell line:The inhibitory effects of [allyl trisulfide], MMC [mitomycin] alone or combined on MGC [humangastric adenocarcinoma] tumor in nude mice were observed...The in vitro test of combinations oftwo drugs showed that [allyl trisulfide] plus MMC or 5 FU plus DDP had markedly synergisticeffect on MGC cells...The inhibition test on the growth of MGC tumor in nude mice indicated thatthe inhibition rates of [allyl trisulfide], MMC alone or combined were 58.3%, 86.3% and 84.3%.The systemic toxic effect of MMC alone was severe, whereas [allyl trisulfide] alone or MMC plus[allyl trisulfide] showed mild toxicity. For this reason, [allyl trisulfide] plus MMC is recommendedfor clinical trials on poorly differentiated gastric cancer ( 1107 ).Using a thioallyl derived from garlic, Yellin and his colleagues examined the relationship betweenglutathione metabolism and sensitivity to chemotherapeutic agents such as cisplatin. They used abattery of cell lines derived from previously untreated head and neck squamous cell carcinomas:An inverse relationship between GSH [glutathione] levels and cisplatin sensitivity wasidentified...Cells were treated with S-allyl cysteine (SAC), a thioallyl derivative isolated from garlic(Allium sativum)...Pretreatment with SAC to lower cellular glutathione levels followed by exposureto cisplatin significantly enhanced the cytotoxic effects of cisplatin, while SAC alone had no effecton cell growth ( 1108 ).In this study, while the garlic derivative used demonstrated no anticancer activity itself, it didenhance the effects of cisplatin. Another intriguing implication of this study was that the presenceof the antioxidant glutathione in some way inhibited the sensitivity to cisplatin, evidence thatantioxidant supplementation might not be useful for patients using some chemotherapies.In another study indicating garlic's potential usefulness as an adjunct to chemotherapies, Chineseresearchers Zhao and Huang screened vegetables for possible inhibition of mutagenicity caused byantineoplastic drugs:We found that 7 out of 11 kinds of commonly eaten vegetables had the ability to inhibit mutagenicity118

caused by chemical drugs such as Mitomycin C, Bleomycinia, Fluorouracil, Cis-Diaminodichloroplatinum, Arabinosylcytosin and mustargen. They were garlic, green Chineseonion, onion, garlic bulb, tomato, cucumber and water radish...We believe that our results can behelpful in the preparation of cancer patients' diet, who are receiving chemotherapy and in theprevention of cancer ( 1109 ).Dausch and Nixon cite several studies that examine the mutagenic potential of garlic. Substancesthat are mutagenic promote mutations, or permanent changes in the DNA in the body's cells. Somemutations can potentially lead to cancer. Garlic has been reported to be mutagenic in several speciesof bacteria, but two studies with mice demonstrated no mutagenic effects. In fact, another studywith mice cited by Dausch and Nixon showed that diallyl sulfide was among the most effectiveagents in inhibiting chemically-induced nuclear aberrations.However, a more recent study by M. Takada published in the Japanese Journal of Cancer Researchshows a possible cancer-promoting effect by some organosulfur compounds found in garlic andonions:Four organosulfur compounds from garlic and onions were examined for modifying effects...onneoplasia of the liver in male F344 rats...Isothiocyanic acid isobutyl ester (IAIE), dipropyl trisulfide(DPT), and allyl mercapton (AM) exerted enhancing effects on their development, while dimethyltrisulfide also tended to increase them...These results suggest that IAIE, DPT, and AM promote rathepatocarcinogenesis and their promoting effect might be caused by increased cell proliferationwith increased polyamine biosynthesis. In evaluating relationships between diet and cancer, it isthus appropriate to consider not only a possible protective role of garlic and onions, but alsoenhancing effects ( 1110 ).The research with garlic seems to indicate it may have promise as an adjunctive therapy for cancerbecause of direct anticancer effect, immune stimulation and also possible inhibition of metastases.However, research is unclear on how a patient might best use garlic.Garlic researcher Robert Lin, Ph.D. advises consumers to beware that manufacturers wishing togive the impression that allicin is the main active component in garlic may fortify their productswith this readily made compound. According to Lin:Allicin is a transient and highly unstable compound which is produced when garlic's cellularstructures are ruptured due to cutting and crushing...Once allicin is formed, it decomposes rapidlyand is mostly lost within one day. Since allicin has a germicidal power when added to culturedmicro-organisms, some garlic products have been promoted as drugs for treating infectiousdiseases. The truth is that almost all cooked garlic and garlic products (including so-called garlicsupplements) contain insignificant amounts of allicin. Further, there is no compelling evidenceshowing that allicin is the active compound in the body ( 1111 ).Sundaram and Milner concluded in their study which showed diallyl disulfide inhibitedproliferation of canine mammary tumor cells:Essential oils of garlic are known to contain approximately 60% DADS ...It is impossible at thispoint to extrapolate the quantity of garlic or its oil that would need to be consumed by humanbeings to potentially reduce the growth of neoplastic tissue. Nevertheless, intakes of 20 grams perday have been reported in some areas of the world. This intake has been correlated with areduction in the incidence of stomach cancers ( 1112 ).119

And Legnani found significant effects on fibrinolysis and platelet aggregation the followingresponses to garlic ingestion in humans at a level of 900 mg daily of dried powder and Kiesewetterfound a clinical effect in humans at a level of 800 mg per day.Studies have also employed various garlic derivatives, both oil soluble and water soluble, and, inanimal studies, used both oral administration and injection. These studies seem to indicate thatinjection is a more effective route of administration, though at least three studies did show lifeextension in animals given garlic orally. Further, studies by Marsh and Lamm seem to indicate thatgarlic extracts given intravesically in mice may be significantly more useful as an immunotherapyfor transitional cell carcinoma of the bladder than BCG, while the studies by Takeyama and Hoonindicate the potential for garlic to inhibit the growth of melanoma.A caveat for cancer patients interested in the use of garlic as an adjunct to therapy is research byPruthi showing that, due to the instability of numerous sulfur compounds, the application of heatabove 60 degrees centigrade can cause not only the pungency, but possibly also the medicinalproperties of garlic to be lost ( 1113 ). However, a cold-aged extract from Japanese whole-clove garlichas been developed that allows for the conversion of some of the active components to be convertedin less irritating compounds which also have less odor ( 1114 ).Richard Grossman, a New York-based authority on herbal medicine, recommends Kyolic brandgarlic for patients interested in an aged garlic product which is less pungent than fresh whole garlic.120

Chapter 3.i.: Silybum marianum or Carduus marianus (milk thistle)There is already some bibliography on this plant ( 598-605 ). It belongs to the Asteraceae family, itoriginated and is common in the countries of the Mediterranean basin and the Middle East,particularly in uncultivated, sunny spots. The pharmaceutical preparation is by means of a dryextraction, taken from the flowertops and the seeds, nebulized and titrated in a solution ofSilimarine min. 1.0%.The principle components are the flavonolignans, which are isolated in the form of a mixture ofcondensation products called Silimarine, which represents from 1.5 to 3% of the drug. Furthermore,there are also present notable quantities of lipids (mainly poly-unsaturated) as well as moderatequantities of Beta-sitosterol, Silibinine, Isolibinine and Silichristina.Silimarine mainly performs a protective action on the liver.In fact it is able to protect the hepatocyte from various toxic substances, such as for examplePhallodine, carbon Tetrachloride, Galactosamine, Thioacetamide etc.In the case of Phallodine, the protective effect of Silimarine is to be attributed to the competitiveblock of the Phallodine link to the receptors situated on the surface of the hepatocyte membrane. Inthis way the Phallodine is prevented from penetrating to the inside of the hepatocyte; Silybummarianum is also able to stimulate the formation of new hepatocytes more quickly than thephallodine is able to destroy them.This indicates that it may be able to stimulate proteic synthesis in the hepatocytes.Silimarine also has a stabilizing effect on the hepatocyte membrane and on the internal membranesof the cytoplasmatic organelles, which can probably be attributed to its action of inhibiting lipidicperoxidation, as a consequence of its ability to capture the free radicals. Silimarine’s ability tostabilize the membrane can therefore be traced to its ability to inhibit the turn-over of thephospholipidic components of the hepatocyte membranes, and its ability to reduce to a considerableextent the speed of the exchange process of the bases on the membrane level. It would thereforeseem that inhibiting this system produces a stabilization of the membrane metabolism. This leads, inthe final analysis, to an inhibition in the formation of lipoperoxides.Silimarine induces a considerable decrease in the transaminases, in GT gamma, in lacticdehydrogenases(LDH) and in bilirubin, in patients with hepatopathy caused by viral hepatitis(types A, B and C) and ethylic hepatitis (through the reduction of aldehyde thanks to the stimulationof dehydrogenase-alcohol).It is also able to protect the liver when it is damaged, induced both iatrogenically and by toxicsubstances such as insecticides, antiparasites or by agents inadvertently introduced into the foodchain such as Falloid Amanita.Its antioxidative action can also be attributed in part to its proven ability to increase the hepaticlevels of Glutathione, by means of a mechanism which is so far unknown.Its action of decreasing total cholesterol and the triglicerides must be highlighted, attributable, inpart, to a better activation of the hepatic metabolism, with consequent optimal use of the lipidic poolby the hepatocyte.The recommended daily dosage is between 600 mg and 1,200 mg, taken in two doses, preferablybetween meals.It must be highlighted that it reduces insulin resistance in chronic hepatitis, with a consequentdecrease in glycemia and glycosuria. It also accelerates protein biosynthesis and accelerates cellularregeneration. It inhibits the production of leukotrienes carrying out an anti-inflammatory action and,in part, an anti-allergic action too. Because of the presence of a moderate amount of Tyramine someauthors advise administering it with a certain degree of caution in the case of hypertension.Because of its Tyramine content, it could also interfere with anti-MAO medicines, which in anycase it is no longer advisable to prescribe in pharmacological therapy.121

Chapter 3.l: LycopeneLycopene is one of the principle carotenoids, and it is found almost exclusively in tomatoes(Solanum lycopersicum), representing about 50% of all the plasmatic carotenoids.Among all the carotenoids, Lycopene has the highest anti-oxidant ability known ( 625,626 ); itsperformance compared with phytochemical derivatives of exotic plants, or little-known plants, isstill being evaluated.Another property of Lycopene is its strong presence respectively in the testicles, the suprarenalglands and the prostate. The reason is not known: however it is suspected that if it is deficient, thiscan be at the root of specific pathologies such as tumors. Thus, an inverse marked connectionbetween the level of Lycopene and tumors in the prostate area (and in the gastric and pancreaticareas too) has been observed, and therefore there has been the suggestion to look for theconcentration of Lycopene in the blood, which should be very low in patients with tumors (similarto what has already been shown by Cameron with regard to vitamin C [SEE chap.3.c]).The amounts of Lycopene present in plasma and in the skin are comparable with those of beta-Carotene. When the skin is under oxidative stress from ultraviolet radiation, a larger amount ofLycopene is destroyed compared to beta-Carotene, suggesting, therefore, a role for Lycopene as ananti-oxidative factor.Lycopene, which is contained above all in tomatoes, is particularly efficient in prostate carcinomas( 633,1359 ) In this work, researchers from the University of Illinois, Chicago, studied men whoconsumed tomato sauce-based dishes (30 mg/day of Lycopene) for three weeks preceding a radicalprostatectomy. They dicovered that after the dietary intervention, serum and prostate Lycopeneconcentrations were significantly increased. In addition, compared with pre-intervention levels,leukocyte oxidative DNA damage was significantly reduced and prostate tissue oxidative damagewas also lower in the Lycopene group than the control group( 1359 ): Longwer Chen: Oxidative DNA damage in prostate cancer Patients consuming tomato sauce-based entrees as awhole-food intervention, Journal of the National Cancer Institute Vol. 93, No. 24, pp.. 1872-1879, 2001http://www.erbeofficinali.org/dati/nacci/studi/licopene%20(pomodoro)%20induce%20il%20PSA%20nel%20CANCRO%20della%20PROSTATA.pdf122

Chapter 3.m: organic acidsOrganic acids, which are among the thousands of co-enzymatic factors contained above all in citrusfruits, grapes, apples, pears, bilberries, blackberries and other fruits of the forest, have a particularprotective role.The Malic acid, Citric acid, Tartaric acid and Tannic acid present in variable proportions, andtherefore responsible for the different flavors that the fruit has, play a particular role in themaintenance of the health of mankind.Contrary to what people think, these acids, once they have been absorbed by the intestine andpassed into the blood supply, do not have an acidifying effect, but an alkalizing effect. In fact, sincethey are "weak acids", they degrade easily in the presence of oxygen, thus producing carbonic acid.The latter combines with sodium and above all with potassium to form carbonates and bicarbonates.Together, these newly formed molecules are called "alkaline reserve", and it makes up that resourcewhich the organism uses to neutralize acids of different origin which form inside it during thecourse of many pathological illnesses such as cancer.Fruits of the forest, citrus fruits, apples and pears are therefore absolutely necessary for theorganism, especially if it is ill, and they should be always eaten uncooked and fresh.NOTE : all rich of vitamin B 17 (SEE chap. 7)Chapter 3.n: Hippocrates SoupFor one person use a 4-quart pot, assemble the following vegetables, then cover with distilled water:1 medium celery knob (or 3 to 4 stalks of celery), 1 medium parsley root (if available), garlic, 2small leeks (if not available, replace with 2 medium onions), 1,5 Ibs tomatoes or more, 2 mediumonions, and a little parsley.Do not peel any of these special soup vegetables; just wash and scrub them well and cut themcoarsely; simmer them slowly for 2 hours, then put them through a food mill in small portions; onlyfibers should be left. Vary the amount of water used for cooking according to taste and desiredconsistency. Keep well covered in refrigerator no longer than 2 days. Warm up as much as neededeach time.123

Chapter 3.o: Organic ZincZinc acts as a membrane stabiliser, and also as a thymic factor ( 581 ). It is therefore important for theproduction of T lymphocytes. With low Zinc content, the working of the fagocytes, cell immunity,antibody immunity and the whole Immune Cascade is reduced ( 582 ).Working together with vitaminE, it inhibits the production of inflammatory prostoglandins and leucotriens.It is also a component of Superoxide Dismutasis (SOD) and takes part in over 200 knownenzymatic reactions, of which many are anti-oxidative and repair DNA.Organic Zinc is necessary for Laetrile therapy (vitamin B17).Zinc is found in Aloe arborescens, in oysters, herrings, the seeds of Cucurbita maxima or moscata(pumpkin), or in Cucurbita pepo (courgettes), in wholewheat cereals.It counteracts Copper (which is often toxic for the organism, and found in dried fruit), Zinc reducesits absorption.Zinc is found in Spices [Anethum graveolens (dill), Pimpinella anisum (anise), Ocimum sanctum ortenuiflorum (basil), Cinnamomum zeylanicum (cinnamon), Elettaria cardamomum (cardamom),Eugenia caryophyllata or Caryophyllus aromaticus (cloves), Coriandrum sativum (coriander),Carum carvi (cumin), Carum nigrum or Nigella sativa (black cumin), Curcuma longa (turmeric),Artemisia dracunculus (tarragon), Melissa officinalis (balm-mint), Mentha species (mint), Myristicafragrans (nutmeg), Origanum vulgare (oregano), Majorana hortensis (marjoram), Capsicumfrutescens, fasciculatum aut annum (cayenne pepper, paprika), Cochlearia armoracia (radish),Rosmarinus officinalis (rosemary), Salvia officinalis (sage), Schinus molle (Brazilian peppertree),Sinapsis arvensis or alba (mustard), Thymus vulgaris (time), Crocus sativus (saffron), Piper nigrum(black pepper), and Zingiber officinalis (ginger)].An adult should take about 20 milligrams of organic Zinc a day, much more in the case of cancerpatients for Laetrile and/or B 17 therapy.124

Chapter 3.p: HoneyCurrently the honeys commercially available are different and they can be summed up thus ( 614 ),while it remains true that no potential anti-neoplastic activity has been noted on an apoptotic basis(or an immune-stimulating one) due to the flowers from which the honey comes; what is more,some of the honeys could contain excessive amounts of glucose, so it becomes dangerous to takethem (evaluation of risk/benefit with the amount taken of the effective active principle).It is therefore useful to list the best-known honeys which are produced from one flower:(Taken from “Honey, a miracle of nature, curative properties, uses and recipes with honey, pollen and Royaljelly”(Miele, un miracolo della natura, proprietà curative, usi e rimedi con miele, polline e pappa reale, DemetraS.R.L. March 1997 edition, 3712 Bussolengo, VR, pp. 21-24).1) Fir honey (Abies): a very dark color, almost black, very aromatic, with a pleasant flavor. It isconsidered an excellent antiseptic for the lungs, and the respiratory system (bronchitis, tracheitis,rhinitis and influenza), able to produce anti-pyretic, expectorant and spasmolytic effects.2) Acacia honey: a clear color, amber, transparent, a sweet smell, a delicate flavor and a liquidaspect. It is particularly indicated for infants and children, particularly if they have inflammation ofthe mucous membranes of the respiratory and gastro-intestinal systems, provided that it isn’tpasteurized. It is rich in levulose making it very tolerable for diabetics, in small doses. It also has amild laxative effect.N.B. According to the author levulose is compatible, in small doses, for neoplastic patients too.3) Orange honey (Citrus aurantium): a clear color, perfumed, a pleasant flavor. It has antispasmodicand sedative attributes which make it advisable in cases of nervousness, anxiety andinsomnia: It has cicatrizant power and is indicated in the treatment of ulcers.4) Hawthorn honey (Crataegus oxyacantha or monogyna): a slight amber color, a sweet andpleasant flavor, perfumed, a slight granular aspect. It is called “ the honey of heart patients”,because it is prescribed in cases of hypertension, palpitations, Angina pectoris, arteriosclerosis,spasms and convulsions. It is also indicated for insomnia. It is thought to have an anti-cancer action.5) Chestnut Honey (Castanea vesca or sativa): there are both nectar and honeydew types, it is adark brown color, varying from a light nut color to a dark almost black nut color, it has a strong,bitter smell and the flavor is bitter, often with a sticky consistency. It is particularly rich in mineralsalts. It is known for its sudorific, expectorant and stimulant properties. It is prescribed for anemia,tiredness and for people overweight.6) Colza honey: a pale, orange color, not much smell, a bland flavor, average granulation, quickcrystallization. It does not have a good reputation and is mainly used in the food industry.7) Arbutus berry honey (Arbutus unedo): a characteristic of the Mediterranean scrub, it has a whiteor grey-green color and a penetrating smell, it has a very bitter flavor and a thick consistency. It isan astringent, a diuretic, an antiseptic for the urinary passages and anti-asthmatic.8) Lucerne/Alfalfa honey (Medicago sativa): an intense yellow color. It has anti-spasmodic,diuretic, laxative, tonic and energetic properties.9) Heather honey: there are different types of heather honey. Generally their color varies from clearamber to dark red, a semi-liquid consistency, a particular flavor and a strong smell. It is rich inmineral salts and has diuretic and anti-rheumatic properties. It is a disinfectant for the urinarypassages and a restorative. Its effectiveness against gout has been proved.10) Eucalyptus honey (Eucalyptus globulus): the color varies between clear and grey-brown, it has aparticularly aromatic flavor and fine granulation. It is one of the richest honeys in enzymes. It isknown for its anti-asthmatic, anti-catarrh, and anti-spasmodic properties. It is an emollient, a coughsoother, an antiseptic for the respiratory tracts, the urinary passages and the intestine. It is effectiveagainst urinary cystitis. It is also used as a vermifuge and a cicatrizant for mouth sores.125

11) Strawberry honey (Fragaria vesca):a light rosy nut color. It has anti-rheumatic, digestive anddiuretic properties. It is particularly indicated for those who suffer from kidney stones.12) Sunflower honey (Helianthus annuus): an intense yellow color. It has diuretic, stimulant,exudative and (particularly in children) anti-pyretic properties.13) Lavender honey (Lavandula officinalis) a white color, with a pleasant and perfumed smell, adelicate flavor, an oily consistency. It can be used for external use for burns, insect bites andinfected sores; it is in fact an excellent antiseptic, recommended in cases of infectious diseases. It isalso a diuretic, vermifuge and good for insomnia.14) Rosemary honey (Rosmarinus officinalis): it has an almost solid consistency and is very grainy,it is from white to pale gold in color, a pleasant smell and a delicate flavor. It is the best honey forthose who have hepatic problems: it helps the decongestion of the liver, the regression of jaundiceand it helps an insufficient liver to work well, in short it helps against all the infectious diseases ofthis organ such as viral hepatitis. It is a good overall stimulant, and is prescribed in cases oftiredness, it is excellent for the stomach and the intestine, fighting flatulence, fermentations andcolitis.15) Sulla/French Honeysuckle honey: a clear color, almost white, fine crystallization, it has adelicate flavor. It has laxative, diuretic, tonic and depurative properties. It is an excellent honey forculinary use because it does not alter the flavor of the foods it is added to.16) Lime honey (Tilia tomentosa, cordata, argentea): a pasty consistency, the color varies fromlight yellow to light green and brown in the case of honeydew, it has a strong smell: It has calmingand anti-spasmodic properties, it is therefore recommended in cases of nervousness and insomnia.17) Thyme honey (Tymus vulgaris): a dark amber color, a strong smell and flavor, irregularcrystallization: It is considered a powerful, general antiseptic for use in case of danger frominfectious diseases, but also as a disinfectant for the bronchioles and the intestine. It has also beenused for inflammation of the uterus.126

Chapter 3.q: other anti-oxidative phyto-medicinesThere are numerous plants which can be used: their association is complex and goes beyond the aimof this study. Basically, having to protect the patient particularly from the free radicals due to theinflammatory processes induced respectively by Immune-Therapy (SEE chap. 9), external Radio-Therapy and Hyperthermia, it is necessary to list the following phyto-medicines consideredessential to follow the multi-factor treatment well which is described in this book, since they haveno immune-depletory action and, on the contrary, they have a considerable anti-edemigene ability.They are:1) Achillea millefolium (yarrow): it contains an essential oil, similar to that of Matricariachamomilla, containing Azulene and some types of lactones, which have an anti-inflammatoryaction.2) The bark of Aesculus hippocastanum (horse-chestnut): rich in coumarin derivatives andbioflavonoids, it increases the resistance of the capillaries, decreasing their permeability, withan anti-inflammatory and anti-endemigene effect.3) The bulb of Allium sativum: rich in Germanium 132 and Allyle Sulphur, it stimulates theproduction of Glutathione Peroxidase. It is hypoglycemic, hypocholesterilizing, antiseptic,hypotensive and a vessel-dilator on the peripheral circuit; its anti-bacterial and anti-fungalaction is considerable against Staphylococcus aureaus, E coli, Candida albicans, Shighellasonnei and Salmonella tiphy; it increases the fibrinlithic activity and it is a good platelet antiaggregant.4) Aloe arborescens mixed with good quality biologically produced honey (SEE chap. 9.b): it ishypoglycemic, hypocholesterilizing, antiseptic and radio-protective.5) Ammi visnaga: its fruit is currently under evaluation, to study the slight side effects (nausea andvomiting) and the possible serious effects; it acts on the arteries; it is also known for its markedspasmolytic action on the pulmonary bronchioles in cases of asthma.6) Arnica montana: its internal use is being evaluated, like Bellis perennis (both are used onlyexternally), because it could cause hematuria and damage to the tubular ephithelium; it cancause an increase in the transminases and in gamma GT.7) Bellis perennis (daisy): its internal use is being evaluated, like Arnica montana (both are usedonly externally); because it could cause hematuria and damage to the tubular ephithelium; it cancause an increase in the transminases and in gamma GT.8) The ripe fruit of Capsicum frutescens or fasciculatum (red pepper, cayenne pepper) and/orCapsicum annum (paprika): they contain Capsaicine, Capsicine, Oleoresine, Capsantine,Quercitine, Esperidine, Eridietrine, vitamins C, PP, E, A, malonic acid and citroflavonoids.They have an anti-oxidant, antibiotic, and painkilling effect; in small doses they have proveduseful in cases of gastritis, hemorrhoids, chronic catarrh of both the pharynx and the tube andchronic earache.9) Chrysantellum americanum: contains both flavonoids and saponines, it increases the tone in theveins and decreases the permeability of the capillaries.10) Chyonatus virginica (the fresh bark of the roots): it contains the glycoside chionantine, similarto saponine; it protects the liver and is perhaps effective against diabetes.11) Collinsonia canadensis or Pareira brava; a saponic glycoside, it is being evaluated for therapyof inflammatory processes in the small pelvis, cystitis, cystopyelitis, urethritis, hypertrophy ofthe prostate, and diathesis for kidney stones. It helps circulation in the small pelvic area andhelps problems caused by stagnation in the whole pelvic area.127

12) The dried stalk and flower stems of Crocus sativus (saffron): under evaluation; its etheric oilcontains Terpene, Crocine, and Picrocrocine; it is anti-hemorrhaging and anti-inflammatory.The stems would seem to have an anti-tumoral action.13) The juice of raw and biologically grown Daucus carota (carrot): very rich in vitamins A,C andE.14) Dracontium loretense: it is considered one of the best plants for its specific anti-oxidant powers,and certainly regarded as superior to synthetic vitamin E ( 566 ).15) The fruit of Embelia ribes: anti-helminthic, especially against ascarids and tapeworms; it has ananti-bacterial action; embeline reduces lipo-peroxidation in the liver, the intestine and thekidneys, increasing the levels of anti-oxidative endogene enzymes; embeline potassium,contained in the fruit, has an analgesic activity; it also has a laxative, carminative and diureticaction.16) Eucalyptus globosus: effective for acute inflammatory processes.17) Eucalyptus officinalis: effective for inflammation of the eyes and pharyngitis.18) Extract of Ginkgo biloba: it is rich in flavonoids, flavones and leuco-anthocyans; somebisflavonoids (Ginketol, Isoginketol, Bilabetol) act on the cellular membranes and stabilizethem; ginkolide blocks lipidic peroxidation and the formation of free radicals; it also inhibits theplatelet activation factor (PAF), thus reducing the risk of thrombosis. N.B. it is counterindicated in subjects with coagulation disturbances; it is inadvisable to use it in combinationwith platelet anti-aggregants. It is effective against Amiotrophic Lateral Sclerosis ( 722 ). Thefruits of the plant are, however, toxic.19) Glycyrrrhiza glabra (liquorice): its roots and its rhyzome contain anti-inflammatory substances.If it is taken for more than 20 days, however, it may cause hypertension.20) Hamamelis virginiana (amamelide, witch-hazel): it is particularly rich in flavenoids, phenolicacid, colline and mineral salts; it is an excellent venous vessel-constrictor, it decreases capillarypermeability and increases the resistance of the vessel walls, reabsorbing the edemas.21) Harpagophytum procumbens (devil's claw): only the secondary tuberized roots should be used;like aloe arborescens it has a good anti-inflammatory action without any side effects of theFANS or especially of the cortisones (which are immune depressors); it has no toxicity and hasa good analgesic effect. It should always be taken on a full stomach and is unadvisable forpregnant women or children under the age of twelve.22) The dried flowers of Hibiscus sabdariffa: used empirically for phlebopathies of various natures;apoptosis on leukaemia ( 692 ), SEE chap. 6.23) Hydrocotile asiatica: it contains asiatic acid, madecassic acid, Asiaticoside, Madecassoside,tannins, phytosterols, resins and mineral salts: a universal cicatrizant; it prevents ulcers andvenous dystrophy.24) The spores of Lycopodium clavatum: they contain oil with Hexadecanic, miristic and licopodicacid; beta-Sisterol and bi-hydrocoffeic acid. N.B. it also contains Aluminum.25) Medicago sativa (alfalfa, lucerne): useful because it contains vitamin K; it is also a radioprotector( 588 ), and an antibiotic against salmonella ( 589 ). Note: has Lysine.26) Melilotus officinalis (yellow melilot): it has an anti-edema action due to the coumarins and theflavonoids which are able to reduce venous and lymphatic stagnation.27) Momordica charantia (African watermelon): the juices of its fruit have proved to beparticularly effective as an anti-oxidative; alpha-momocharine, a glycoprotein isolated from itsseeds, inhibits the growth of some tumoral lines: furthermore this molecule increases thetumoricide effect of the macrophages of mice on mastocimal murine cells. Its fruit is effectiveagainst leucemia in humans ( 639 ).28) Myrciaria paraensis (kamu kamu): an exotic fruit which contains 50 to 100 times more vitaminC than Citrus aurantium.29) Myrica cerifera: it protects the liver and is also thought to have an immune stimulating action.128

30) Myristica fragrans (nutmeg): the dried seeds are gastro-protective, also effective against gastroduodenitisand gastro-enteritis.31) The fresh stalks of Myrillocactus geometrizans: a vessel protector, empiric studies have shownthat it has a high ability to aid post-infarction coronary and myocardia recovery, and canpossibly reactivate the arterial circuit in other areas: it is being evaluated for possible sideeffects.32) Myrrhis odorata (myrrh, sweet cicely): vessel-protecting properties on both the capillaries andthe veins.33) Nepeta cataria: the whole plant, useful for acute inflammatory processes.34) Okoubaka aubrevillei: the wood and the dried, pulverized bark; it has a detoxifying effect with aprotective action on the air passages; it would seem to be effective against toxoplasmosis:suspected enzymatic pancreatic-like action.35) The leaves of Perilla ocymoides: in Japanese literature ( 610 ) it has been proposed as an antioxidativetogether with 72 other plants considered; it is effective against uric diatesis and hyperuricemia.36) The roots of Picrorrhiza kurroa: it protects the liver and is also effective in cases of previousmetabolic-toxic damage or of chronic hepatic illnesses; it is immune-stimulating, anti-viral andanti-helminthic.37) The dried wood of Quassia amara: it contains quassin and neoquassin, it is a useful protector ofthe liver in hepatopathies, cholangitis and stagnant veins.38) The leaves of Ribes nigrum: it contains more than 500 different types of flavenoids with aconsiderable anti-oxidative effect. It must, however, be used with caution on patients withhypertension, because of its DOCA-like action. It has the same counter indications as the use ofcortisonics. It is also a potent diuretic; it eliminates uric acid; it has anti-inflammatory propertiesand is therefore indicated together with Harpagophytum procumbens.39) The dried branches and the leaves of Rhododendron campylocarpum or aureum or chrysanthum(rhododenron, alpine rhododendron): Andromedotoxin, Ericolin, glycoside Rhododendrin; it isanti-inflammatory and anti-rheumatic.40) The roots of Ruscus aculeatus (holly, butcher's broom and wild asparagus): a potent vesselconstrictor,anti-inflammatory and anti-edemigene.41) The bark of Salix alba: like Filipendula ulmaria and Aloe arborescens it contains salicylates.42) The flowers of Sambucus nigra: it is one of the best anti-phlogistic plants existing in nature. It isprescribed for respiratory and urinary inflammations; it is anti-oxidative, diuretic, daiphoretic, asoothing hypertensive, a laxative and anti-neuralgic; it is also suspected of having an immunestimulatingaction; it is being evaluated for leukaemia.43) The fresh, ripe berries of Serenoa repens (dwarf palm): they contain antranilic acid, tanningsubstances and Carotene. They are effective in cases of prostate hypertrophy, cystitis,epididimitis and prostatitis; it is being evaluated for carcinomas of the prostate.44) Spiraea ulmaria or Filipendula ulmaria (olmaria): like Salix alba and Aloe arborescens itcontains salicylates, and thus has an anti-inflammatory action.45) Symphytum officinale (comfrey): used empirically for bruises, trombophlebitis; it is the onlyvegetable rich in vitamin B12, it is therefore inadvisable.46) The leaves of Vaccinium myrtillus (bilberry): it improves the venous circle because it is rich inbioflavenoids. N.B. the juice of its berries have an important antiseptic action on the urinarypassages because they contain hippuric acid.47) The berries of Vaccinum vitis idaea (red bilberry): they contain more than 500 different types offlavenoids with considerable effects such as anti-oxidative, vessel-protective, antiinflammatory;in particular it seems able to induce apoptosis in some forms of tumor.48) The ripe fruit of Vitex agnus castus: it is still being evaluated for possible side effects.49) The leaves, seeds and juice of Vitis vinifera (black grape): it is rich in tannins and anthocyans;the latter protect from the oxidant substances acting on the venous walls.129

50) In 1989, in Japan, 72 plants were tested as protective factors against the effects of ionizingradiation: 16 of them, in the following order, showed high anti-oxidative capacities: Rosacanina (fruit), Aloe arborescens, Citrus leiocarpa (exocarp), Schizonepeta, Evodia rutaecarpa(fruit), Bupleurum chinese (roots), Cornus sanguinea (fruit), Perilla ocymoides (herb),Anemarrhena (rhyzome), Mentha piperata (herb), Trapaeolum maius (fruit), Angelica dahurica(roots), Sinomenus (rhyzome), Ephedra vulgaris (herb), Acer nikoense (bark), Forsythia (fruit)( 610 ).51) The xantofilins (Lutein, Zeaxantin) have an anti-oxidative activity, interrupting the peroxidationreactions of the phospholipidic membranes ( 634 ).52) Others: Copper and Manganese, obtainable from various natural sources, are useful for theactivity of the anti-oxidant enzyme SOD and for the Immune Cascade complex. Copper, inparticular, in a ferrooxidasic activity can be considered synergetic with Iron itself: the best ratiobetween Iron and Copper must be about 1:12, going up to as much as 24:12 in infections, andthis explains the strengthening of the immune defenses exerted by the assimilation of bothcopper and Iron.130

Chapter 4Phyto medicines with anti-infection activityThe immune system at a gastro-intestinal level is the most developed because of the antigenic loadthe organism is exposed to: the cutaneous surface is only 2 square meters, that of the lungs is 80square meters whilst that of the gastro-intestinal area is 300 square meters.The gastro-intestinal immune system, being highly developed, justifies the action of many phytotherapiesadministered orally to induce a specific immune stimulation towards particular naturalantigens such as lecitins for example (SEE chapter 4.f).Disturbances in the gastro-intestinal tract, especially if they are induced and sustained by parasitesor fungi, have a strong negative affect on the immune defense system of the human organism.The causes of this serious alteration in the capacity of the human immune defense system aremanifold , beginning with disbiosis, characterized by the replacement of normal aerobe bacteria byaerobe pathogens and finally by anaerobes and fungi, opening the way to potential super-infectionsof a parasitic type, causing the worst form of disbiosis (granulocytosis based on eosinophilics).Gastro-intestinal disbiosis is therefore a serious alteration of the normal intestinal bacterial flora,which leads to a gradual alteration in the intestinal mucus tissue (above all in the colon) andtherefore of the lymphocytes present in the mesenteric lymph nodes, in the Peyer plates, in thelamina itself etc….This alteration in the normal intestinal flora causes not only a gradual alteration of the working ofthe lymphatic tissue present in the intestinal mucus, but also a gradual block of the immune-lymphstructure located at some distance away, which can perhaps be correlated even with differentpathologies such as ulcerous colitis, Crohn’s disease, an immune imbalance and hepatopathy.In particular it is suspected that a great number of food allergies are traceable to serious forms ofintestinal disbiosis.Given that intestinal parasitosis is the most common cause of the most serious disbiosis, the foodscan be divided into three groups:1) Foods which do not cause intestinal disbiosis: cereals and their derivatives.2) Foods which cause intestinal disbiosis. Milk and its derivatives (above all cheese), eggs,cakes, jellies, sugars (with the exception of fructose, honey, the juice of Acer campestris(Canadian maple); GMO foods which have already shown a depletory action on thelymphocytes such as insecticide maize for example ( 788-792 ) and, most probably, other GMOfoods of the same type based on Bacillus thuringiensis.3) Foods which prevent intestinal disbiosis: acidic foods, above all apple vinegar.There are pharmacological therapies which can seriously compromise the gastro-intestinal immunedefense thus starting a disbiosis: The most serious is Chemo-Therapy (even in mini doses),followed by cortisones and synthesized antibiotics.Other factors, of less importance, are psychological stress, ovulation inhibitors, mercury poisoning(from amalgam in dental fillings), preservatives, colorants, irradiated food or food cooked in amicrowave oven and a deficiency in natural symbionts (lactobacillus).The risk of infection from parasites is very often undervalued, because it is considered of lowincidence rate in the high food standard of daily life. In reality the risk is high and raw vegetablesmust be washed at least 4 times (avoiding, however, water with chlorine because of the relativeproblems of vitamin deficiency).131

Raw vegetables in our diet are of prime importance, but if the vegetables are not washed, the risk ofinfection is real.Fish and shellfish are also a complex problem; they should only be bought from recognizedfishmongers. Fresh fish should always be put on ice and kept on ice.Parasitosis from foods is very common in the third world, and particular attention should be paid tofood (vegetables, fruit, fish etc..) coming from those countries which have poor hygiene.In many countries in the third world little attention is paid to the type of water used to irrigate thesoil, very often the water has been recently mixed with “sewage water”, “black water”, pollutedwater from the cesspits of the local communities.This problem is also connected with the question of pesticides, chlorine and other toxic compoundsused in high quantities in the third world to increase production for export, to the detriment ofvitamins and oligo-elements of organic agriculture.Very often, safe levels of pesticides and fertilizers are exceeded, thus rendering the food toxicbecause of chemical pollution.In this way the food obtained (fruit and vegetables in particular) is seriously deficient in vitaminsand vitamin co-factors (SEE chapters 3 and 9) and, on the contrary, is contaminated with chemicalpoisons.Phyto-therapies with a known anti-parasitic and anti-mycotic action1) Aegle marmelos (India): it acts on Candida albicans2) Artemisia cina: effective against ascarids.3) Azadirachta indica (India) effective against intestinal worms4) Bambusa arundinacea (India): effective against intestinal parasites: N.B. it is suspected ofhaving an apoptosis and pseudo-apoptosis action on some types of tumor.5) Berberis aristata: effective against malarial fever, the extracts of this plant are thought to bemore effective than quinine, because it does not provoke cardiac depression and/or damageto hearing. It is also a hepatic-protector and helps the spleen.6) Boerhaavia diffusa (India): its roots have anti-heminthic properties (also a diuretic, laxativeand expectorant effect).7) Butea frondosa (India): effective against Ascaris lumbricoides and Toxocara canis.8) The seeds of Curcubita pepo (courgettes): an anti-parasitic activity (N.B: also very rich inZinc).9) The fruit of Embelia ribes: anti-helminthic, effective particularly against ascarids andtapeworm; it has an anti-bacterial action. Embeline reduces lipo-peroxidation in the liver,the intestines and the kidneys, increasing the levels of endogene anti-oxidative enzymes.Potassium embelate, contained in the fruit, shows an analgesic activity, it is also known forits laxative, carminative and diuretic action.10) Cuminum cyminum: its dried, mature fruit has anti-fungi and anti-microbe activity.11) The rhizome of Curcuma longa: turmeric (“the saffron of the Indies or the poor”) is antihelminthicand an immune stimulant; it also has pronounced anti-inflammatory activities, itis an hepatic protector from carbon tetra-chloride.12) Ficus religiosa (the bark of its branches): an anti-protozoal against Entamoeba histolytica, ithas an anti-helminthic activity against Ascarida galli.13) The bark of Holarrhena antidysenterica: anti-inflammatory, anti-pyretic, an immunestimulant. The alkaloid Conessine is effective against dysentery caused by Entamoebahistolytica, it is lethal against protozoa, and to a limited extent against Trichomas hominis.Narconessine, isoconnesine and kurchine are currently being studied: recently two new132

alkaloids have been identified: Holacine and Holacimine (with a suspected apoptosis actionon the cancer).14) The alcoholic extract from the leaves of Asparagus racemosus also inhibit the growth ofEntomoeba histolytica (N.B: it also has an anti-tumor effect in vitro against human skincarcinomas and carcinomas of the nasopharynx ( 700,752 ).15) Inula racemosa: an anti-fungi activity comparable to Nistatine, but not as good asAmphotericine B. It also has anti-inflammatory, anti-pyretic and anti-spasmodic activities.16) Inula helenium: a European variant of the Indian one; currently being evaluated for the samepurposes.17) Picrorrhiza kurroa: anti-helminthic.18) Tribulus terrestris: anti helminthic and an immune stimulant; induce apotosis onosteosarcoma (it has Diosmin [ 1134 ]).19) Acido caprilico: a fatty acid which is extracted from coconuts and palm oil; it dissolves thecell membrane of Candida albicans and of other fungi. It is absorbed well by the intestine,and distributes itself evenly in the colon, where the colonization of Candida albicans ismore common.20) Metil sulfonilmethane: a sulphur based compound, it is present in most foods, but is easilydegradable in cooking. It has proved effective against some parasitic forms (Giardiaintestinalis, Tricomonas vaginalsi): It also acts as an anti-oxidative.The following help in anti-parasitic treatment: Brassica oleracea, Var capitata, Cynara scolymus(an anti-oxidant, hepatic protector and diuretic), Matricaria chamomilla, Sida cordifolia, Ocimumbasilicum, sanctum or tenuiflorum, and another….Milk enzymes are also very useful such as L. acidophilus, cultivated in the juice of vegetableswithout lactose and milk derivatives or preparations which are not milk derivatives, these, too, mustbe without sugar except fructose (e.g. Milk Free Acidophilus Long Life ®, NutraMaxidophilus®,etc).Note 1: they should be taken between meals.Note 2: the possible addition of FOS needs to be evaluated (a possible glycemic uptake on the partof the tumors has not been noted), in view of a possible alternative to the systematic use ofantibiotics to cure recurring infections in cancer patients whose immune system is compromised(SEE ‘antibiotics’, infra).Note 3: also Avena sativa, rich in vitamins B1, B2, B6 and Inositol, helps the development ofintestinal bacterial flora, and is therefore able, by means of controlling the fermenting processes atan intestinal level, to reduce an excessive production of intestinal gases.Note 4: in inflammations of the intestine, of bacterial origin, vegetable carbon exercises anabsorbing effect on intestinal bacterial pathogens.AntibioticsThe use of antibiotics could be necessary in the treatment of patients who are immune-depressedfrom Chemo-Therapy, even if, as was pointed out in chapter 2, any form of Chemo-Therapy shouldbe rejected, since it is irremediably depletory and invalidating to the immune defense system of thepatient himself, as well as for all the other reasons cited in chapter 2.Note: Cortisone, too, should not be used under any circumstances, except in situations which cannot be treated by antiinflammatory(FANS) or anti-inflammatory phyto-therapy medicines (SEE chapter 14). Cortisone could be useful incases of cerebral tumor.133

With regard to phyto-medicines used as antibiotics the following are worthy of mention:Ailantus glandulosa is currently being studied, with its fresh shoots, its flowers (potential honey)and its bark; an anti-tumor activity cannot be excluded a priori, given that its effectiveness onpathologies of neck and tonsil lymph nodes is well-known.Alchornea castanefolia has proved effective against varieties of Staphylococcus aureus, E. coli, andAspergillum niger which have become resistant to penicillin G.Aloe arborescens or vera, for use as an antibiotic, should also be considered ( 12, 58, 140, 162, 163, 262,486 ).Many plants have been shown to have an antibiotic action: one particular one is the essential oil ofMelaleuca alternifolia, which is particularly effective against bacteria and fungi.Allium sativum, rich in Germanium 132 and in Allile sulphide, has a marked antibacterial activityagainst Staphylococcus aureus, E. coli, Shigella sonnei and Salmonella tiphy, it has proved usefulagainst Meningococcus; it has an anti-fungi action against Candida albicans, it also stimulates theproduction of glutatione peroxidase.The roots of Aralia racemosa ease the expectoration of mucus from the respiratory tracts, above allif the cough persists at night: It is also suspected of having anti-tumor potential.The roots of Arctium lappa cut in the first year of growth, in autumn, or in the second year, inspring, before it flowers, have an antibiotic action (coffee acid).The essential oil of Azadirachta indica is a good antibiotic against Staphylococcus aureus, and E.coli; (it is effective against all types of intestinal worms, SEE parasitosis).Chimaphila umbellata has proven effective against cystitis, chronic cystopyelitis, uric acid andhypertrophy of the prostate. It is suspected of having an anti-cancer action on breast tumors.Centaurea cyanus is effective against styes.Cetraria islandica or Lichen islandicus has an anti-bacteria and anti-viral activity because of themucilaginous substances it contains. It also has a gastro-protective ability. On the other hand,because of two of the components (Lichenine and Isolichenine) which lead, in hydrolysis water, tothe formation of Galactose, it is counter indicated in the feeding of cancer patients, except inminimum quantities.Phyllanthus niruri inhibits polmerase DNA in hepatitis B.Primula veris or officinalis is effective as an expectorant and a painkiller for bronchitis.Sida cordifolia strengthens the immune defenses; it is an anti-mycotic, anti-bacterial, anti-viral andanti-helminthic. It does, however, contain Ephedrine, a toxic substance, which is particularlydangerous for heart patients or with hypertension. It should be administered only in doses which adoctor considers safe for the patient.Terminalia belerica also has an anti-bacterial action.Terminalia chebula is useful against urinary and eye infections; it also contains Anthraquinone.134

Tinospora cordifolia can be compared to Gentamicine in peritonitis caused by E. coli.The berries of Vaccinium myrtillus have an important antiseptic action on the urinary tract becauseof their juice which contain hypuric acid. This inhibits the adhesion of germs to the tissue of theurinary apparatus. What is more the high vitamin C content causes acidification in the urine.Other plants with an antibiotic action are Cuminum cyminum (this also has an anti-fungi action),Cyperus rotondus, Picrorrhiza kurroa (viral hepatitis), Piper longum (anti-bacteria, hepatoprotector),Tephorosia purpurea (viral hepatitis), Tribulus terrestris, Terminalia belerica, the leavesof Arctostaphylos uva-ursini (cystitis, especially if it is caused by E.coli), and another….135

Chapter 5Phyto-medicines with an anti-uricemic activityDespite not eating foods with nucleic acids (meat, fish, eggs, milk and its derivatives), the patientbegins to have high levels of uric acid in the blood, with the possible onset of renal damage.The high increase in uric acid is caused by apoptosis phenomena in the cancer cells (SEE chapter6), by the Immune cascade (SEE chapter 9), and by the breakdown of the tumor growth by enzymes(SEE chapter 7). All these phenomena cause the death of a large number of tumor cells…Together with or as an alternative to Allopurinol various phyto-medicines are effective ineliminating uric acid which has been induced by the immune therapy.Note 1: the use of Allopurinol in cancer patients is still regarded as unadvisable (until there isevidence to the contrary).The following is a list of phyto-medicines with curing properties for prostate hypertrophy, cystitis,nephritis and kidney stones.1. Adlumia fungosa: it is still being evaluated for possible side effects.2. Agropyrum repens: it is also useful as a diuretic and anti-edemigene plant.3. Berberis vulgaris: effective for uric diathesis, nephropathy and kidney stones.4. Betula alba: (N.B. it also has an apoptotic action on melanomas, SEE chapter 6).5. A decoction of the seeds of Celastrus paniculatus6. Citrus limonum: a diuretic, it is effective in the prevention of kidney stones.7. Chimaphila umbellata: it is useful for cystitis, chronic cystopyelitis and hypertrophy of theprostate gland. It is also suspected of having an anti-cancer effect on breast tumors.8. Erigeron canadensis: it is also useful as a diuretic plant.9. Eupatorium perfoliatum or purpureum: purpureum is preferable as an anti-uricemic andantiseptic of the urinary tract, but both plants are immune stimulating.10. Fabiana imbricata: effective for uricemic diathesis, kidney stones, cystitis and prostatitis.11. Fraxinus excelsior: according to some sources it is the best natural uricosuric agent.12. Harpagophitum procumbens: very effective.13. Hieracium pilosella : an anti-uricemic of recent clinical evaluation.14. Mahonia aquifolium: effective for uric diathesis, nephropathy and kidney stones. It is alsostrangely effective against psoriasis, and hence a potential anti-neoplastic activity issuspected, perhaps with an apoptotic base.15. Ononis spinosa: a diuretic action due to saponine.16. Orthosiphon stamineus: a diuretic plant, effective in cases of uricemia. It is also useful at ahepatic-biliary level.17. The leaves of Perilla ocymoides: effective for uric diathesis, hyperuricemia. It is alsoeffective as an anti-oxidative.18. Petroselinum crispum or sativum: effective for cystalgia, urethritis and hepatopathy.19. Populus tremuloides: use the fresh inside bark of the young branches and the leaves. It isuseful for acute or chronic cystitis, hypertrophy of the prostate gland and uric acid.20. Solidago virga aurea: also used for chronic nephrytis, hypertrophy of the prostate gland andcystitis.21. Urtica dioica: it is also a remineraliser of proven effectiveness; unfortunately it contains alot of proteins.136

22. The berries of Vaccinum vitis idea: arbutine is a diuretic and disinfectant for commoninfections of the urinary tract (cystitis, urethritis etc) given that it is then metabolized andeliminated by the kidneys, liberating hydroquinone. What is more there are over 500different types of flavonoids with a considerable anti-oxidative, vaso-protective and antiinflammatoryeffect. It could have an ability to induce apoptosis in some forms of tumors.Rudolf Breuss’ renal preparation:It is also possible to prepare at home some formulas which have been famous for more than a century in popularmedicine such as Rudolf Breuss’ renal preparation:15 grams of Equisetum arvense10 grams of Urtica dioica (according to the author, that picked in spring is the best)8 grams of Polygonum aviculare8 grams of Hypericum perforatumPut half a tablespoon in a cup of boiling water and leave to infuse for 10 minutes, then strain, putthe liquid aside and add to the remaining grounds 2 cups of hot water and boil for a further 10minutes. Then strain again and mix the 2 tisanes together. It is advisable to drink this 3 times a day.In the East various formulas for the preparation of effective herbs are used against serious prostatepathologies ( 703 ) : Epidium bevicornum (the stems and aerial parts), Morinda officinalis (the roots),Rosa laevigata (the fruit), Rubus chigius (the fruit), Schisandra chinensis (the fruit), Ligustrumlucidum (the fruit), Cuscuta chinensis (the seeds), Psoralea corylifolia (the fruit) and Astragalusmembranaceus. SEE this scientific paper in INTERNET to:http://www.erbeofficinali.org/dati/nacci/studi/Equiguard%209%20erbe%20cinesi%20contro%20il%20cancro%20della%prostata.pdf or on : http://www.erbeofficinali.org/dati/nacci/allpdf.php137

Chapter 6Phyto medicines with a Bio-Chemo-Therapy action:plants which have a “suicide affect” on Cancer.Fresh plants contain thousands of vitamins which are able to activate our immune system againstgerms, viruses or tumour cells, or even to induce apoptosis (cell suicide or programmed cell death –SEE note) in tumour cells.The plant with anti-cancer properties (apoptosis and/or immunostimulation) must not damagehuman organs or tissues and must therefore be eaten fresh, as a real PHYTOTHERAPICPRODUCT.In many cases, it can also be taken in the form of INFUSION (TEA or DECOCTION), with orwithout the addition of other substances, for example alcoholic ones, according to EXPERTS’prescriptions.It is generally advisable to eat raw fresh plants with the addition of honey, provided that they haveno toxic side effects, as for example the Salvia species, which must be taken in the form of TEA inorder to eliminate the very dangerous Thujone…Amounts of vitamins needed to induce apoptosis in a certain number of tumour cells in thelaboratory without damaging healthy human cells are really very small.The following is a report of several scientific studies showing the actual ability of these vitamins toinduce cell suicide in various tumours. Amounts needed are measurable in a few dozens ofmicromoles/litre, i.e. picomoles/microlitres.As far as apoptosis-inducing vitamins are concerned, Tatman’s fundamental scientific study ishighly recommended. His book lists about 180 different isoprenoids (Tatman H., Cancer Letters 175,2002, pp. 129-139).http://www.erbeofficinali.org/dati/nacci/studi/TATMAN%20(%20ARTICOLO%SUGLI%20%20ISOPRENOIDI).pdfIn this book “Mille Piante per guarire dal Cancro senza Chemio” (“Thousand Plants againstCancer without Chemotherapy”, issue DECEMBER 2007, the author M.D. Giuseppe Naccirecommends using fresh preparations of these plants with the addition of honey, similarly to whatFather Romano Zago suggested for the preparation of Aloe arborescens, for example: since ancienttimes HONEY has traditionally been added in twice the amount of the plant used (blended, ground,crushed, etc.).HONEY is very important because it protects the precious vitamins from air oxidation and gastricjuices and allows them to be absorbed by patients’ intestinal walls. Furthermore, honey is apowerful antiseptic preventing germs from destroying vitamins. Several types of honey also havereal healing properties as they are obtained from flowers of medicinal plants.138

PLEASE NOTE: As known to Ayurvedic Indian Medicine for thousands of years, patients affected by malignanttumours must never take plant SPROUTS, as they usually contain ALL 9 ESSENTIAL AMINO ACIDS, FOLIC ACIDand Vitamin B12, a fact that WESTERN MEDICINE also discovered recently.The following is a collection of significant scientific papers which can help doctors choose the mostsuitable plants for healing each malignant tumour (http://www.erbeofficinali.org/dati/nacci/allpdf.php ).The papers, almost all of them available in PDF format, can be found in the scientific literature andindicate the amounts of vitamins which are needed to induce APOPTOSIS in the cancerous cell lineconsidered. The amounts are measurable in micromoles, i.e. micromoles/litre, i.e.nanomoles/millilitre, i.e picomoles/microlitre. The studies generally demonstrate that these plantsalmost never have side effects on healthy cells.PLEASE NOTE: Reading the articles will make it clear that the amounts of vitamins needed to induce APOPTOSIS canchange depending on tissular Ph, on oxygen quantity and above all on the time they remain in the tumour…Aloe arborescens, maybe the most famous plant among those currently studied, contains Emodin, afluorescent anthraquinone inducing a selective apoptosis only in tumour cells.Please find three PDFs attached at the end of this work, including Palù G.: Aloe-Emodin is a newtype of anticancer agent with selective activity against neuroectodermal tumors, Cancer Research,60, pp. 2800-2804, 2000. [PDF http://www.erbeofficinali.org/dati/nacci/allpdf.php ]ApoptosisBy apoptosis we mean the activation of specific endonuclease which break up DNA, acting at thelevel of the nucleosomic sites which make up the primary structural unit of the nuclear chromatin ofthe cell. The induction molecules, in general deriving from plants (phyto-chemical), induceapoptosis in neoplastic cells, by activating proteolytic intracellular enzymes, which cause thedeterioration by proteolysis of the vital sequence of the DNA, thus causing the death of the cellthrough apoptosis. In anti-neoplastic therapy these molecules have to reactivate the suicidecommand in the tumor cells, without causing damage to the healthy cells. Initial clinical experiencehas already found in Emodine, contained in Aloe, a good example of a particularly selectivemolecule for certain types of human tumor, like vitamins A, D and E.The deliberate attempt on the part of companies producing GMO to deactivate (with Fortilin, Bcl-2,Bcl-xl) this precious natural mechanism contained in plants is very serious. This phenomenon ofblocking apoptosis (anti-apoptosis action), already introduced experimentally into tobacco plants bymeans of a virus ( 748,751 ), is according to the author a deliberate act of damage inflicted on theecosystem by GMO: a damage which, if it is propagated to plants commonly used in the food chain,could render the cure of tumors and other serious illnesses completely impossible using the methodproposed in this study.Pseudo-ApoptosisThere are also vegetable substances (and perhaps even, by means of chemical synthesis, ofpharmaceutical origin) which have the ability to be absorbed by membrane molecules exclusivelypresent in certain human tumor cells, and therefore introduced to the inside of the diseased cell.Since all cellular membranes have the same structure, these molecules also become absorbed at thelevel of the lysosomial membrane, damaging it. De Duve ( 84 ) had defined lysosomes as “suicidevesicles”, and, if their membrane is damaged by toxic agents, it becomes permeable to enzymescontained in it, which thus digest the cell itself. This phenomenon is partly reminiscent of apoptosis:in practice, a cellular suicide induced by enzymes present in the DNA itself of the cell, that is to139

say, the activation of specific endonucleases which break up the DNA, acting at the level ofnucleosomic sites which make up the primary structural unit of the nuclear chromatin of the cell(SEE also:Emodine-Aloe). But, in this case, they are extraneous molecules which interfere with theintegrity of the membrane of the lysosomes, and not with the DNA structure, as for example in thecase of the berries of Pittosporum tobira and Chamerops excelsa ( 84 ).Chapter 6.a : the plantsAnother form of apoptosis was discovered by a Japanese study in the case of neuroblastomas, whichtend to regress when a certain amount of H-Ras protein has accumulated in cells ( 1042-43 )http://www.erbeofficinali.org/dati/nacci/studi/articolo%20sul%20NONU%20(morinda%20citrifolia)%20attiva%20contro%20tumore%20al%20cervello_2.pdfIt probably occurs also in the case of glioblastomas (astrocytomas of III or IV degree ofmalignancy). It was observed that this kind of tumour regressed in human beings afteradministering plant extracts inducing the production of the same vitamin (H-Ras) in glioblastomas.( 1173 )http://www.erbeofficinali.org/dati/nacci/studi/Suicidio%20di%20cellule%20tumorali%20del%20cervello%20(glioblastomi)%20e%20del%20cancro%20gastrico%20via%20APOPTOSI-INDIPENDENTE.pdfIn the case of brain tumours, Morinda citrifolia extracts are particularly important ( 1043 ).which induced RAS expression and caspase-independent Neuroblastoma cell death.http://www.erbeofficinali.org/dati/nacci/studi/articolo%20sul%20NONU%20(morinda%20citrifolia)%20attiva%20contro%20tumore%20al%20cervello_2.pdfOther plants such as Hypericum perforatum, Melissa officinalis, Momordica carantia, Betula alba,Yucca schidigera ( 1118 ) and Gardenia species are currently being studied ( 1061 )http://www.erbeofficinali.org/dati/nacci/studi/Geniposide,%20contenuto%20nel%20frutto%20di%20Gardenia,%20fa%20suicidare%20cellule%20del%20tumore%20del%20cervello.pdf.Alpha-Bisabolol, a sesquiterpene alcohol in Chamomile (Matricaria chamomilla) essential oil,could be considered as a promising inducer of apoptosis in highly malignant glioma cells ( 1568 )A significant effect on the treatment of glioma was reported using Elemene which is found in smallamounts in many essential oils: it prolonged quality survival time of 40 patients with glioma ( 1574 )(Tan P.: Clinical study on treatment of 40 cases of malignant brain tumor by Elemene emulsion injection, Chin. J.Integ. Trad. Western Med, 20, pp.: 645-648, 2000) http://www.mednat.org/cancro/cancro_cervello.pdfNote: Morinda citrifolia is inhibition of angiogenic initiation and disruption of newly establishedhuman vascular ( 1172 ).http://www.erbeofficinali.org/dati/nacci/studi/articolo%20sul%20NONU%20(morinda%20citrifolia)%20attiva%20contro%20tumore%20al%20cervello_1.pdfThe author therefore prefers to use the term Pseudo-Apoptosis, to better differentiate thismechanism from Apoptosis proper, as described above.-----------------------------One particular aspect concerns medicines, phyto-medicines, vitamin substances or minerals, or ofother types, which have a selective anti-tumoral action on cancer cells alone, by means of inducingapoptosis or pseudo-apoptosis like (from: http://www.erbeofficinali.org/dati/nacci/allpdf.php )140

The cruciferous vegetables ( 809 )http://www.erbeofficinali.org/dati/nacci/studi/INDOLI%20e%20ISOTIOCIANATI%20delle%20crucifere%20o%20%20brassicacee.pdfGlucosinolates ( 1137 ) http://www.erbeofficinali.org/dati/nacci/studi/Glucosinolati.pdfVolatile isoprenoid constituents of fruit, vegetables and herbs, for leukaemia and melanoma ( 1141 )http://www.erbeofficinali.org/dati/nacci/studi/TATMAN%20(%20ARTICOLO%SUGLI%20%20ISOPRENOIDI).pdfBioflavonoids for Leukaemia ( 1130 ) http://www.erbeofficinali.org/dati/nacci/studi/azione%20di%20antileucemia%20dei%20bioflavonoidi_2.pdfBaicalin and Baicalein ( 718, 1563,1564 ).Quercetin for Leukaemia ( 1146, 1561 )http://www.erbeofficinali.org/dati/nacci/studi/Quercitina%20apoptosi%20su%20LEUCEMIA.pdf )Quercetin for oral cancer ( 1370 ) http://www.erbeofficinali.org/dati/nacci/studi/quercetina.pdfQuercetin for oesophageal adenocarcinoma ( 1560 ) and colonrectal cancer ( 1562 )Limonene induces the formation of apoptotic bodies on BCG-823 gastric cancer cells in a dose-andtime –dependent manner ( 1565 ) and induced significant reductions of hepatocellular carcinomas( 1566 ). Limonene showed anti-angiogenic and pro-apoptotic effects on human gastric cancerimplanted in nude mice, thus inhibiting tumor growth and metastasis ( 1577 ).Essential oil of lemon balm (Melissa officinalis) was found to be effective against a series of humancancer cell lines ( 1567 ).Artemisia annua induced apoptosis of hepatocarcinoma (Li Y.: Induction of apoptosis of culturedhepatocarcinoma cell by essential oil of Artemisia annua ( 1569 )Eucalyptol (Eucalyptus globules, Elettaria cardamomum) on human leukaemia HL-60 cells showedinduction of apoptosis ( 1570 )The essential oil of Melaleuca alternifolia and its major monoterpene alcohol (terpinen 4-ol) wereable to induce caspase – dependent apoptosis in human melanoma cells ( 1571 ).http://www.erbeofficinali.org/dati/nacci/studi/terpenoide%20di%20olio%20di%20Melaleuca%20alternifolia%20induce%20apoptosi%20su%20MELANOMA.pdfThe essential oil of Tetraclinis articulate (conifer tree) showed the hallmarks of apoptosis whentested on a number of human cancer cell lines including melanoma, breast and ovarian cancer inaddition to peripheral blood lymphocytes ( 1572 )Cudrania tricuspidata induces apoptosis in human leukaemia ( 1573 )Pomegranate seed oil (Punica granatum) contains a coniugated trienoic fatty acid as a principalingredient, which can induce apoptosis in several cancer cell ( 1576 )Alisma plantago acquatica induces apoptosis in human acute lymphoblastic leukaemia and humanfibrosarcoma ( 1559-1600 ) http://www.erbeofficinali.org/dati/nacci/studi/ALISMA%20PLANTAGO-AQUATICA.pdf141

Ellipticine of Ochrosia elliptica for breast cancer ( 1135 )http://www.erbeofficinali.org/dati/nacci/studi/Ocrosia%20elliptica%20induce%20apoptosi%20su%20cancro%20della%20mammella.pdfCarnosic acid ( 712 ).Diosmin (as Tribulus terrestris) induce apoptosis on osteosarcoma ( 1134 )http://www.erbeofficinali.org/dati/nacci/studi/DIOSGENINA%20fa%20suicidare%20cellule%20dell’OSTEOSARCOMA.pdfBetulinic acid for melanoma, neuroblastoma, leukaemia, malignant brain-tumors ( 1036-1041,1127,1128,1166, 1603 ) http://www.erbeofficinali.org/dati/nacci/studi/betulla_1.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/betulla_2.pdf http://www.erbeofficinali.org/dati/nacci/studi/betulla_3.pdf )http://www.erbeofficinali.org/dati/nacci/studi/Acido%20betulinico%20induce%20apoptosi%20su%20tumori%20neuroectodermali.pdfMimosa species ( 1142 ) http://www.erbeofficinali.org/dati/nacci/studi/MIMOSA%20fa%20suicidare%20cellule%20tumorali.pdfThe berries of Pittosporum tobira and Chamerops excelsa ( 84 ).Emodine-aloe ( 333,487,715 ) http://www.erbeofficinali.org/dati/nacci/allpdf.phphttp://www.aloearborescens.tripod.com/studi.htmFlavonoids ( 1122 ) http://www.erbeofficinali.org/dati/nacci/studi/Flavonoidi%20promettenti%20agenti%20anticancro.pdfCatechin ( 1123,1186 ),Vitamins A, D and E (SEE chap.3).Citrus limonum ( 693 )http://www.erbeofficinali.org/dati/nacci/FLAVONOIDI%20contenuti%20nel%20Limone20%provocano%20APOPTOSI.pdfAllium sativum ( 694,696,1369 ) http://www.erbeofficinali.org/dati/nacci/studi/aglio_provoca_apoptosi_del_cancro_del_polmone.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/AGLIO%20provoca%20apoptosi%20in%20cancro%20della%20PROSTATA_2.pdf ;http://www.erbeofficinali.org/dati/nacci/studi/aglio%20induce%20apoptosi%20sulla%20leucemia%20mieloide%20cronica.htmhttp://www.erbeofficinali.org/dati/nacci/studi/DIFFERENZA%20fra%20ALLINASI%20di%20AGLIO%20FRESCO%20ed%estratto.pdfRosmarinus officinalis ( 1062 ).Sutherlandia frutescens ( 1147 ) http://www.erbeofficinali.org/dati/nacci/studi/sutherlandia%20frutescens.pdfUncaria tomentosa and Uncaria guianensis ( 714, 1606 ) http://www.erbeofficinali.org/dati/nacci/studi/Uncaria_species.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/Uncaria_species%20azione%20antiproliferativa%20degli%20acidi%20uncarinici%20di%20Uncaria.pdfAcacetin ( 1165 )http://www.erbeofficinali.org/dati/nacci/studi/ACACETINA%20induce%20APOPTOSI%20su%20cancro%20del%20fegato.pdfTwo bioflavonoids (Apigenin and Quercetin) inhibit metastatic potential of melanoma ( 1609 )http://www.erbeofficinali.org/dati/nacci/studi/allpdf.phpThe metanolic extract of the flowers of Hypericum perforatum, Vaccinium vitis idaea, Bacopamonnieri ( 640 ),Various flavenoids (Wagonin, Fisetin) for human hepatic-carcinoma ( 713 ).142

Capsicum frutescens, fasciculatum or annuum on leukaemia and prostate cancer ( 1351,1598 )http://www.erbeofficinali.org/dati/nacci/studi/peperoncino%20efficace%20su%20leucemia.pdf )http://www.erbeofficinali.org/dati/nacci/studi/Capsaicina%20(peperoncino)%20induce%20APOPTOSI%20in%20cellule%20del%20cancro%20della%20prostata%20sia%20androgeno-positive%20che%20androgeno-negative.pdfCurcumina induce apoptosis in lung cancer ( 1133 )http://www.erbeofficinali.org/dati/nacci/studi/curcuma%20provoca%20APOPTOSI%20(SUICIDIO)%20di%20cellule%20del%20cancro%20del%20polmone.pdfIt’s in Curcuma longa and Curcuma zedoaria , currently under experiment in vitro only onleukaemia [ 690 ], but already mentioned by Castore Durante even in 1617; inhibition of metastases( 1161 ).Many other plants, still being studied to verify their possible toxicity according to dosage, such as:Thalictrum acutifolium for lung cancer ( 711 ).Sophora flavescens for leukaemia ( 716 )http://www.erbeofficinali.org/dati/nacci/studi/Sophora%20flavescens%20induce%20apoptosi%20su%20leucemia.htmHibiscus sabdaiffa, experimented in vitro only on human leukaemia ( 692 ),http://www.erbeofficinali.org/dati/nacci/studi/ibisco_induce_apoptosi_su_leucemia_e_retinoblastoma.pdfUrsolic acid( 700 )http://www.erbeofficinali.org/dati/nacci/studi/Acido%20ursolico%20(Asparago)%20induce%20apoptosi.htmAltholactone induced apoptosis on leukaemia ( 1125 )http://www.erbeofficinali.org/dati/nacci/studi/altolactone%20induce%20apoptosi%20su%20leucemia.pdfElemene (Curcuma zedoaria and another plants), induced apoptosis in leukaemia ( 1409 ).http://www.erbeofficinali.org/dati/nacci/studi/elemene_zedoaria_provoca_apoptosi_nella_leucemia.pdfOrganic Germanium on lung cancer ( 269 )http://www.erbeofficinali.org/dati/nacci/studi/Germanium%20132%20un%20caso%20clinico%20di%20cancro%20polmonare.pdfCarotenoids induced apoptosis in prostate cancer ( 1366 )http://www.erbeofficinali.org/dati/nacci/studi/carotenoidi%20sono%20fattori%20attivi%20contro%20il%20cancro%20della%20prostata.pdfCianidine 3-Glucoside and Peonidine 3-Glucoside induced apoptosis on cancer ( 1368 )http://www.erbeofficinali.org/dati/nacci/studi/Riso%20indiano%20(CIANIDINE)%20inducono%20APOPTOSI%20su%20cellule%20del%20cancro.pdfFlavonoids and Isoflavonoids ( 1129 ) http://www.erbeofficinali.org/dati/nacci/studi/azione%20di%20antileucemia%20dei%20bioflavonoidi_1.pdf,Alkaloides of Gelsemium sempervirens induced apoptosis on liver cancer ( 699 )http://www.erbeofficinali.org/dati/nacci/studi/alcaloidi%20del%20Gelsemio%20inducono%20apoptosi%20su%20cellule%20tumorali.htmEssential oils of plants induced apoptosis on cancer and leukaemia ( 1371 )http://www.erbeofficinali.org/dati/nacci/studi/gli%20olii%20essenziali%20.pdfManganese Superoxide Dismutasis induced apoptosis on mesotelioma ( 1365 )http://www.erbeofficinali.org/dati/nacci/studi/Manganese-Superossido%20Desmutasi-%20apoptosi%20del%20mesotelioma%20pleurico.pdfCurcumina and Quercitina induced apoptosis on adenoma ( 1410 )http://www.erbeofficinali.org/dati/nacci/studi/cipolla%20e%20curcuma%20efficaci%20contro%20i%20polipi%20precancerosi%20dell’intestino.pdf143

Curcumina and Isothiocyanates (PEITC) induced apoptosis on prostate cancer ( 1352 )http://www.erbeofficinali.org/dati/nacci/studi/curcuma%20longa%20e%20isotiocianati%20(Crucifere).pdfPereskia bleo for breast cancer ( 1144 )http://www.erbeofficinali.org/dati/nacci/studi/PERESKIA%20induce%20apoptosi%20su%20cancro%20della%20mammella.pdfPanax ginseng ( 1170,1171 )http://www.erbeofficinali.org/dati/nacci/studi/GINSENG/%20pianta%20che%20induce%20apoptosi%20su%20molti%20tumori%20maligni_1.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/GINSENG/%20pianta%20che%20induce%20apoptosi%20su%20molti%20tumori%20maligni_2.pdfResveratrol ( 1162 ) in the Polygonum cuspidatum, Vitis vinifera and in Yucca schidigera (1118) whichis characterized by its apoptotic activity p53-dependent on Melanoma, by depolarizingmitochondrial membranes (activating Caspase-9 ) in Acute Leukaemia ( 1121,1148,1605 ), in the Breastcancer ( 1608 ) and also its anti-angiogenese properties ( 695 )http://www.erbeofficinali.org/dati/nacci/studi/resveratrolo_2.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/resveratrolo%20induce%20apoptosi%20su%20melanoma.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/resveratrolo_1.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/Resveratrolo%20induce%20apoptosi%20sulla%20Leucemia.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/allpdf.phpGordonia axillaris, tested on human tumors ( 698 ) http://www.erbeofficinali.org/dati/nacci/studi/camellina%20B_(english).pdfThe rhizome of Atractylodes ovata tested on leukaemia ( 704 ).Solanum lyratum for cancer of the liver ( 705 )http://www.erbeofficinali.org/dati/nacci/studi/apoptosi%20di%20cancro%del%20fegato%20con%20varie%20piante%20cinesi_1.pdfLepidozamia peroffskyana ( 1044 ).Boswellia carterii tested on leukaemia ( 704 ).Drinaria fortunei which has proven effective against human osteoclast ( 717 ), and according to theauthor should be tried on osteolithic bone metastasis or Multiple Myeloma.Phyllanthus urinaria against lung cancer ( 720 )http://www.erbeofficinali.org/dati/nacci/studi/PHYLLATHUS%20provoca%20APOPTOSI%20su%20tumori.pdfSalvia miltiorrhiza is still being evaluated for its possible toxic effects (Tujone), but apoptosis onepatocarcinoma ( 708,1115,1116 ) http://www.erbeofficinali.org/dati/nacci/studi/salvia%20%20induce%20apoptosi%20su%20tumori.pdfand Leukaemia ( 1575 )Camellia sinensis ( 173,1123,1124, 1159, 1160,1164,1186 ) http://www.erbeofficinali.org/dati/nacci/studi/the%20verde_2.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/the%20verde_3.pdfTartary buckwheat flavonoid activates caspase 3 and induces apoptosis in cancer ( 1064 ).Zingiber officinale (6-paradol) activates caspase 3 ( 1143 )http://www.erbeofficinali.org/dati/nacci/studi/Zenzero%20induce%20APOPTOSI%20su%20LEUCEMIA%20con%206-paradolo%20e%206-gingerolo.pdfSesquiterpene lactone parthenolide, the principal active component in medicinal plants (es.:Tanacetum parthenium), induced apoptosis in toumors, depletion of Glutathione, generation ofreactive oxygen species, activation of Caspases 7,8,9, overexpression of GADD153, an anticanceragent inducibile gene, and subsequent apoptotic cell death. ( 701 )144

http://www.erbeofficinali.org/dati/nacci/studi/PARTENOLIDE%20induce%20APOPTOSI%20su%20diversi%20tipi%20di%20tumori%20maligno.pdfGoniothalamin of Goniothalamus species ( 1138,1139 )http://www.erbeofficinali.org/dati/nacci/GONIOTALAMINA%20induce%20APOPTOSI%20su%20cellule%20della%20LEUCEMIA_1.pdfhttp://www.erbeofficinali.org/dati/nacci/GONIOTALAMINA%20induce%20APOPTOSI%20su%20cellule%20della%20LEUCEMIA_2.pdfBoswellic acid induces apoptosis in metastatic melanoma and fibrosarcoma ( 1131 )http://www.erbeofficinali.org/dati/nacci/studi/acido%20boswellico%20induce%20apoptosi%20su%20cellule%20del%20melanoma%20e%20del%20fibrosarcoma.pdfCitrus species induced apoptosis in cancer, with beta Cryptoxanthin and Hesperidin ( 1063 )http://www.erbeofficinali.org/dati/nacci/studi/Ciproxantina%20e%20Esperidina.pdfIn Calabria (Italy) Citrus aurantium bergamia (Bergamot orange) is being cultivated.In the following work, many food plants included in the diet of several people and havingadvantageous medical properties are reported ( 1149-1153 ).Spinaches also have effects on papillomas ( 1154 )http://www.erbeofficinali.org/dati/nacci/studi/spinaci%20sono%20efficaci%20su%20papillomi_(english).phpEqually important is organic Selenium ( 1155 )http://www.erbeofficinali.org/dati/nacci/studi/Selenio%20induce%20APOPTOSI%20su%20cellule%20del%20carcinoma.pdfAlpinia oxyphylla (Zingiberaceae) in human promielocytic leukaemia ( 1156 )http://www.erbeofficinali.org/dati/nacci/studi/alpinia%20species%20induce%20apoptosi%20su%20leucemia%20promielocitica.pdf ).Another process of apoptosis induced by woodfordin I in human leukaemia K562 cells ( 1157 )http://www.erbeofficinali.org/dati/nacci/studi/EPILOBIO%20Chamaenerion%20angustifolium%20(woodfordin%201)%20induce%20apoptosi%20su%20leucemia.pdfChlorophyllin and chlorophyll are modulation of apoptosis ( 1158 )http://www.erbeofficinali.org/dati/nacci/studi/clorofilla%20e%20clorofillina%20inducono%20APOPTOSI.pdfPentacyclic triterpenes from Chrysobalanaceae species have cytotoxicity on leukaemia ( 1167 ).Inhibition of human breast cancer growth by Genistein ( 1168 )http://www.erbeofficinali.org/dati/nacci/studi/GENISTEINA%20fa%20suicidare%20cellule%20del%20cancro%20della%20mammella.pdfSeveral major ingredients of Chinese herbal medicines are under study in human hepatoma ( 1169 ).http://www.erbeofficinali.org/dati/nacci/studi/apoptosi%20di%20cancro%del%20fegato%20con%20varie%20piante%20cinesi_2.pdfAnche l’alcool perillico induce apoptosi di tumori, sia cancri che leucemie ( 1556-1559 )http://www.erbeofficinali.org/dati/nacci/studi/Perillyl%20alcohol%20(Monoterpene)%20against%20cancer.pdf )http://www.erbeofficinali.org/dati/nacci/studi/Perillyl%20alcohol%20(Monoterpene)%20induces%20APOPTOSIS%20on%20CARCINOMA.pdf )http://www.erbeofficinali.org/dati/nacci/studi/Perillyl%20alcohol%20inhibits%20human%20breast%20cancer.pdf )http://www.erbeofficinali.org/dati/nacci/studi/Anti-leukaemia%20effects%20of%20Perillyl%20alcohol.pdf )Anche l’estratto di radice di Solanum dulcamara ha dimostrato di provocare apoptosi nelle celluledel cancro della prostata e delle sue metastasi ( 1655 )http://www.erbeofficinali.org/dati/nacci/studi/Dulcamara%20solanacea%20induce%20apoptosi%20nel%20cancro%20della%20prostata.pdfFra i tanti Indoli, è da ricordare la Glucobrassicina, contenuta nelle Brassicacee, che determinaapoptosi nel cancro della mammella. In particolare, essa è contenuta nella Isatis tintoria ( 1656 )145

http://www.erbeofficinali.org/dati/nacci/studi/Isatis%20tinctoria%20(glucobrassicina)%20induce%20apoptosi%20nel%20cancro.pdfMany other plants exist, and have been collected in particular extracts for therapeutic use, not onlyas plants with potential apoptotic and pseudo apoptotic use but also as immune stimulating plants(chap.9) and/or with an anti-oxidative action (SEE chap.3).On the basis of recent discoveries about the apoptotic induction of the seeds of Momordicacharantia ( 639 ), particular interest is currently being shown to the seeds of other plants such asHelianthus annuus (sunflower); Citrus paradisi (grapefruit); Cucumis melo (melon); Cucumissativus (cucumber); Citrullus vulgaris (water melon, red melon); Solanum lycopersicum (tomato);Solanum melongena (aubergine/eggplant); Rubus idaeus (raspberry); Actinidia chinensis (kiwi);Citrus aurantium (orange) and Vitis vinifera.A matter of grave concern is that large GMO seed firms are putting on the global agriculturalmarket fruits with no seeds inside, in particular the following: Cucumis melo, Citrus limonum,Citrullus vulgaris, Solanum lycopersicum, Vitis vinifera.Seeds are deemed significant anti-cancer agents essentially because they contain the well-knownvitamin B17 (SEE chapter 7).Another modifications are: GMO-Brassica rapa (turnip, 968 ), GMO-Brassica oleracea botrytis(cauliflower, 968 ), Prunus domestica ( 1013 ), Citrus paradisi ( 1014 ),etc….Pueraria species induced apoptosis on human toumors for the contents of Antocyanin (apoptosis ontoumors) but the contents of Antocyanin of the Pueraria GMO were dramatically decreased by 40%( 1119 ) http://www.mednat.org/alimentazione/PUERARIA.pdf)It is a particularly serious thing to try to genetically modify Allium sativum (Cultivated garlic) andAllum cepa (Garden onion) because these plants contain particularly precious anti-cancersubstances (SEE chapter 3).Recently, also Solanum Lycopersicum (tomato) has been made a target for the introduction ofGMO: in particular the gene of the Solanum pennellii has been introduced, thus determining anincreased level of glycemia in this food, causing a further risk in cancer patients and those withdiabetes.The author of this work, dr. Giuseppe Nacci, thinks that genetic modification of plants (GMplants) is an unacceptable damage for human health, not only for the subtraction of vitamin B17in human feeding, but also of many other vitamins that have an apoptotic activity.The question that was asked was thus the following: is it possible that chemo-pharmaceuticalmultinationals, that is, those producing drugs for CHEMO-THERAPY, want to destroy thenatural heritage of hundreds of anti-tumour vitamins contained in fruit and vegetables sothat, in the next decades, they can “cancel out the competition of alternative therapies” thusmaking CHEMO-THERAPY the only possible therapy against cancer?Even though the issue can seem complex, I would like to focus on the following data: thewicked alliance between GMO Multinationals and Chemo-pharmaceutical Multinationals.146

Chapter 6.b.: The perverse alliance of the agro-industrial andchemical-pharmaceutical Multinationals1) Agro-industrial Multinationals (OGM)For some years we have been witnessing the birth of multinationals which define themselves as“science of life multinationals”, which are active in the pharmaceutical market, agri-business (seedsand pesticides) and the veterinary business. They are, in themselves, different sectors, but they arelinked by the use of biotechnology (GMO) to produce their products. These multinationals are usingunscrupulous and aggressive economic strategies: since the beginning of the 90s they have beenworking towards buying companies, even large companies.One of these, Monsanto, within the space of a few years has acquired Asgrov, Agracetus, De Calb,and Cargill investing 10 billion Euros.Another big group, Dupont, has acquired Pioneer, investing about 8 billion Euros.These investments do not seem to have any economic logic: they pay much more for the companiesthan their actual value, as if they were trying to eliminate a potential competitor rather than obtain ashort term economic result.Alongside the acquisitions we also have the mergers: Ciba Geigy and Sandoz created Novartis (witha turnover of 20 billion Euros in the year 1997-98).From the merger of the French company Rhone Poulenc and the German company Hoechst wehave the new company Aventis.Still within this context, Syngenta, the first worldwide agrochemical group was founded in October2000. It is the result of a merger between the Swiss company Novartis (a company well-known forproducing medicines for chemotherapy) and the Anglo-Swedish company Astra-Zeneca (a companyalso well-known for producing medicines for chemotherapy), and will have a turnover of about 8billion euros. Monsanto, after its merger with Pharmacia & Upjohn, a large pharmaceuticalindustry (this too is well-known as a producer of medicines for chemotherapy) now concerns itselfonly with agriculture, with a turnover which in 2000 reached 5.5 billion dollars.The current situation stands thus: a few multinationals (Syngenta, Monsanto, Novartis, Dupont andAventis) have 25-30% of the seed market (but more than 90% of the transgenic seed market) andbehind these big groups there is a plethora of smaller companies which makes one think that thistrend can only get stronger in the future, since medium size companies cannot compete with thesebig groups. The objective seems clear: to convert the traditional seed market into a biotechnical one(that is, GMO). But the worrying fact is that we find the same names in the field of pesticides,where the same companies control 55% of the market, and in the pharmaceutical field where thesame companies play a dominant role.2) Chemical-pharmaceutical Multinationals (Big-Farma)The history of the chemical-pharmaceutical multinationals is incredible because of their rapiddevelopment, and today they are connected to the agro-industrial sector in an extremely dangerousway.The chemical-pharmaceutical industry started in Europe in the second half of the nineteenthcentury: in many cases they were dyeing industries which, moving away from basic chemistry,moved towards the new and more promising fields of specialized chemistry in key economic fields.147

Before the Second World War, a powerful international pharmaceutical cartel developed inGermany. It controlled global pharmaceutical companies and chemical plants and was active in 93countries, representing a powerful economic and political force in each of them. It was known asI.G. Farben. It would become the main supporter of Hitler’s chemical production during the years ofwar, offering products such as high explosives, toxic gases and the ignominious Zyklon-B, the lethalsubstance used by Nazis in the death camps. In 1928, however, before the outbreak of war, theAmerican monopolist manufacturer John D. Rockfeller had merged his international empire inAmerica with I.G. Farben, creating the largest and most powerful pharmaceutical cartel ever seen.The Military Nuremberg Tribunal established in 1946/47 that the Second World War would nothave taken place without this petrochemical cartel called I.G. Farben. As a consequence of thesentence passed by the Tribunal, I.G. Farben was divided into Bayern, BASF and Hoechst, andsome executives were condemned for initiating a war against international law, genocide, theexploitation and looting of private and public properties in foreign countries and other crimesagainst humanity.The events leading to the war and linked to this powerful cartel are reported in Joseph Borkin’s TheCrime and Punishment of IG Farben.After the war, Germany, with its three large companies Bayer, Hoechst and BASF (whichencouraged the rise of Hitler’s national socialism), played an important role. So did Switzerland,which, in Basle, saw the founding and the development of companies Ciba, Sandoz and Roche – allof which later spread throughout the world.But it was in the 1990s that the really big mergers started: in 1989, in the United Kingdom two bigpharmaceutical companies merged to form Smith Kline – Beecham: later they merged withAmerican Home (with an annual turnover of about 25 billion Euros).In 1993 the Swedish company Pharmacia bought the Italian company Farmitalia-Carlo Erba, thenit merged with the American company Upjohn in 1995, and then again with Monsanto, before beingbought by Pfizer which had previously bought the American company Parke Davis.In 1995 there was the Glaxo-Wellcome merger (with an annual turnover of about 14 billion Euros).In 1998 Smith-Kline-Beecham (with an annual turnover of 62 billion Euros) merged with Glaxo-Wellcome (with an annual turnover of about 90 billion Euros) to make an annual turnover of morethan 150 billion Euros.In the meantime the English company Imperial Chemical Industries merged with the Swedishcompany Astra, forming the company Astra-Zeneca.These mergers have continued among the same companies operating in the same field: Santoz andCiba Geigy (Novartis, 1996), Astra-Zeneca (1998).Their turnovers are in the range of the GDP (Gross Domestic Product) of many western countries.These huge companies have not been founded for the good of the patient but out of the need tocreate monopolies and hence ever bigger profits.148

Latest data:June 2002 : Bayer Company to acquire Aventis, IncJune 2002: Aventis was taken over by Bayer. This allowed Bayer to enter the sectorof GMO seeds. The merger brought to the foundation of Bayer CropScience, which iscomposed of three main commercial groups: Crop Protection, Bio Science andEnvironmental Science.June 2005: Sementis was taken over by Monsanto.ST. Louis, Jan. 24, 2005: Monsanto Company to acquire Seminis, Inc., a leadingVegetable and Fruit Seed Company.ST. Louis (Jan. 24, 2005). Monsanto Company announced today that it signed a definitiveagreement to acquire Seminis, Inc., for $ 1,4 billion in cash and assumed debt, plus a performancebasedpayment of up to $ 125 million payable by the end of fiscal year 2007.“…The addition of Seminis will be an excellent fit for our company as global production ofvegetables and fruits, and the trend toward healthier diets, has been growing steadily over the pastseveral years, “ said Hugh Grant, chairman, president and chief executive officer of Monsanto.“Seminis is uniquely positioned to capitalize on this fast-growing segment of agriculture, and theacquisition likewise expands Monsanto’s ability to grow. We look forward to furthering the growthand leadership position established by Alfonso Romo and his team as the Seminis business is animportant extension to our agricultural seeds platform…”Seminis is the global leader in the vegetable and fruit seed industry and their brands are among themost recognized in the vegetable-and-fruit segment of agriculture. Seminis supplies more than 3,500seed varieties to commercial fruit and vegetable growers, dealers, distributors and wholesalers inmore than 150 countries around the world.In addition to Seminis leading presence in the vegetable and fruit seed industry, which is expectedto contribute to Monsanto’s financial results in the near-term, Monsanto management seesadditional benefits longer term. From a technology perspective, Monsanto intends to continue onthe path taken by Seminis for its business which is to focus on developing products via advancedbreeding techniques. Longer term, biotechnology applications could be an option, and will beevaluated in the context of Monsanto’s research-and-development priorities and potentialcommercial business opportunities.149

The perverse allianceOne can thus affirm that the two cardinal points of the economy and the life of the individual,agriculture and pharmaceuticals, are substantially under the control of a few multinational groups.We are faced with a choice: accepting biochemical modifications of plantsleading to immense damage to human health or taking a stand togetherwith the democratic institutions of our society against GMO and chemopharmaceuticalmultinationals, which in their perverse alliance areresponsible for the reckless invasion of GMOs all over the world.150

Chapter 6.cSince these anti-neoplastic effects (apoptosis and pseudo-apoptosis) are released by immune action,as described above (chap.6.1), and since this biochemical action is partially reminiscent oftraditional Chemo-Therapy, that is, the simple administering of drugs either orally or intravenously,but in this case with no serious side effects on the rest of the organism (and particularly on theimmune defenses of the patient), these new substances, according to the author, can be cataloguedas drugs with a biochemotherapy action.It is not yet known exactly if there is a mechanism to induce apoptosis or pseudo-apoptosis inhuman tumors using the following plants: Ochrosia elliptica for breast cancer, Pereskia bleo, Urticadiotica and Lamium album for tumors of the stomach, tumors in female genitalia, lymphomas andleukaemia; Acalypha indica for lung tumors; Malva sivestris or vulgaris for tumors of the larynx;Cetraria islandica for melanoma, bone sarcoma and different types of carcinoma; Resveratrol formelanoma, Epilobium parviflorum and Copaifera officinalis for tumors of the prostate and thebladder; Epilobium angustifolium or Solanum paniculatum for tumors of the uterus; the bark ofBetula alba (birch) for melanoma (betulinic acid); Salvia officinalis for lymphomas, leukaemia,epatocarcinoma, and carcinomas of the pancreas, (it is, however, counter indicated for breasttumors); Mimosa species, Gardenia jasminoides, Quercus robur, Betula alba, Morinda citrifolia,Lepidozamia peroffskyana, Melissa monarda and Melissa officinalis for glioma; Asparagusracemosus for human skin carcinoma and carcinoma of the nasopharynx; Sticta pulmonaria orLobaria pulmonaria, Glechoma hederaceum for melanoma, bone sarcoma and different types ofcarcinoma; Euspongia officinalis for lymphomas; Acorus calamus for gastro-intestinal carcinoma;Rumex acetosa for gastric carcinoma; Equisetum arvense for lymphoma, leukaemia and pancreaticcarcinoma; for tumors of the lungs, kidney and bladder; Chimaphila umbellata for tumors in boththe male and female genital areas; Galium aparine for carcinoma of the tongue; Lysimachianummularia, Artemisia absinthium for gastro-intestinal carcinoma; Phyllantus niruri or Artemisiaabrotanum for peritoneal carcinosis from gastro-intestinal tumors; Marrubium vulgare for breasttumors, Plantago major for melanoma, bone sarcoma and different types of carcinoma; Alchimillaalpina and vulgaris for carcinoma of the female genital area; Meum mutellina for melanoma, bonesarcoma and different types of carcinomas; Bacopa monnieri for sarcomas; Cerastium alpinum forcarcinoma of the breast and lungs; Primula veris or officinalis for lung tumors; Scutellariabaicalensis o latiflora for lung tumors, Gentiana germanica for breast carcinoma; Ailanthusglandulosa for tumors of the head and neck; Nelumbo nucifera for carcinoma of the stomach,Cissampelos pareira per carcinoma and leukaemia, Pimpinella major and saxifraga forcarcinomas of the oral cavity, the neck and the larynx; Mormordica charantia against leukaemia,Antennaria dioica for lung carcinoma; Gnafalium supinum or Erythrina mulungu for carcinoma ofthe stomach, Asparagus cochinensis for tumors of the breast and of the lungs, Verbascum thapsusor densiflorum for melanoma, bone sarcoma and different types of carcinoma; Lapsana communisfor tumors of the breast (hypothesized); Erythroxylum catuaba for melanoma; the flowers ofTrigonella foenum graecum (only in an infusion) for lymphoma, leukaemia and pancreaticcarcinoma; Maytenus illicifolia for cancer and leukaemia, Antyllis alpestris for lung carcinoma,Cerastium alpinum for carcinoma of the stomach; Sida cordifolia for leukaemia, sarcoma andcarcinoma of the nasopharynx; Erithrea antaurium or Boerhaavia diffusa for gastro-intestinalcarcinoma; Houttuynia cordata for lung carcinoma, Inesinae calea for carcinoma and leukaemia;Maytenus krukovit for melanoma; Physalis angulata aut Muehenbeckia volcanica for leukaemia andtesticules tumors, Sempervivum montanum for leukaemia and lymphomas; Cayaponia tayuya forsarcomas, Pfaffia paniculata per cancer and leukaemia, Serenoa repens for carcinoma of theprostate; Uncaria tomentosa for some types of leukaemia; Pedicularis rostrato-capitata forcarcinoma of the breast; Marasdenia cundurango for gastric carcinoma; Primula hirsuta forcarcinoma of the breast; Saxifraga oppositifolia for carcinoma of the breast, the uterus and forleukaemia, Alpinia oxyphylla for leukaemia, Cupressus lusitanica, Argyreia speciosa (or Lettsomia151

nervosa), Aquilaria agallocha, Hypericum richeri, Grindelia camporum or squarrosa, Althaeaofficinalis, Argemone mexicana, Cinnamomum zeylanicum, Myroxylon balsamum, Saxifragaaizoides, Mahonia aquifolium, Pulmonaria angustifolia or officinalis, Bambusa arundinacea,Peucedanum ostruthium, Rubia cordifolia, tinctorium or peregrina, Draba aizoides, Campanulalatifolia, Polygala senega, Smilax sarsaparilla or utilis, Citrullus colocynthis, Albizzia lebbek,Celastrus scadens, Myrica cerifera, Nepeta cataria, Taraxacum officinalis, Galphimia glauca,Adiantum capillus veneris, Drosera rotundifolia, or anglica, or intermedia, Annona squamosa,Thymus serpillum, Sysymbrium officinale, Larrea mexicana, Aralia racemosa, Actinidia chinensis,Crocus sativus, Buxus sempervirens, Viola tricolor, Sambucus nigra, Laurus nobilis, Tephorosiapurpurea, Myristica fragrans and sebifera, Tabebuia impetiginosa, Larrea divaricata, Ecliptaalba, Ailantus glandulosa, Rosmarinus officinalis, Thymus vulgaris, Hyssopus officinalis, Luffaoperculata, Apium graveolens, Artemisia dracunculus, Crataegus oxyacantha or monogyna,Chondrus crispus, Panax ginseng, Ajuga reptans, Ajuga piramidalis, Tinospora cordifolia,Leucanthemopsis alpina, Emblica officinalis, Moringa pterygosperma, Eupatorium perfoliatum, orpurpureum, Glycyrrhiza glabra, Hieracium pilosella, Morinda citrifolia, Xantoxilum fraxineum,Trifolium pratensae, Sutherlandia frutescens, Arctium lappa, Ulmus rubra, Rhodiola rosea, Rumexcrispus, Boswellia serrata, Rheum palmatum or officinale, Echinacea purpurea, angustifolia orpallida, Astragalus membranaceus, Hypoxis hemerocallidea, Lycopodium clavatum, Tribulusterrestris, Picramnia antidesma, Cassia angustifolia, Rhamnus sagrada or purshiana, Rhamnusfrangula, Terminalia chebula, Ocimum basilicum, sanctum o tenuiflorum, Capparis spinosa,Lonicera coprifolia, Cardamine pratensis, Carpinus betulus, Carlina acaulis, Curcuma longa,Holarrhena antidysenterica, Lepidium meyenii, Stachys arvensis, Polygonum aviculare, Geraniumrobertianum, Myrtus communis, Melaleuca alternifoglia, Cinchona calisaya or succirubra,Azadirachta indica, Lepidium meyenii, Calendula silvestris, Schinus molle, Ilex paraguariensis,Cassia occidentalis, Cynara scolymus, Nerium oleander, Phyllanthus orbicularis, Zingiberofficinale, Goniothalamus species, Myroxylon balsamum or pereirae…..There are about 200 other plants proposed by the author (this data is confidential).Note : Selective inhibitions on telomere activityVarious active principles, extracted above all from plants, are currently being studied to verify theirselective anti-telomere activity. It must be remembered that 90% of cancer cells have thischaracteristic, which healthy cells do not. In recent medical literature it has been noted that Uncariatomentosa is thought to have this characteristic.Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of humancancer cells in vitro and in vivo ( 2088 ).There are studies currently underway on extracts from plants such as Camellia sinensis(confidential data).152

Chap. 6.d: The berries of Pittosporum tobira and Chamaerops excelsaConcerning the anti-tumor action carried out by these plants, discovered after 30 years of researchby D’Arrigo ( 84 ) no other studies have been found in literature.The data obtained are significant, however, and deserve further investigation.The advantages are the following:1) no collateral chromosome damage on healthy cells2) no teratogenic effectThe therapeutic doses are different between the two berries. As in the case of apoptosis induced byEmodine-Aloe, these two substances should be tested for all human tumors, to discover their abilityto induce pseudo-apoptosis in the individual clinical case.Furthermore their pharmo-kinetics should be studied as in the case of Emodine-Aloe (SEE table 4),both for oral administration, as in the case of Emodine-Aloe, and also for intra-parenchymaladministration (I.V.).153

Chap. 6.e : LimoneneLimonene, found in lemons (Citrus limonum), oranges (Citrus aurantium), juniper (Juniperuscommunis) Foeniculum vulgare, Mentha pulegium, Mentha spicata, Verbena officinalis,Hyssopus officinalis, and in sage (Salvia officinalis), induces phenomena of apoptosis in leukaemiacells ( 693 ).At least 6-7 lemons a day should be taken, possibly fresh, because lemons help eliminate the acidwastes from the body, increasing the reserves of alkaline substances in the blood and helping theurinary apparatus to expel uric acids. One lemon a day should be taken in the first week, to reach 7lemons a day by the seventh week of the treatment; this should be continued this throughout theillness until the hoped-for cure. The honey from lemon flowers is currently under evaluation.Lemon trees flower all year round, in general they have two principle flowerings which are moreabundant: in April-May and in September. A lemon plant lasts 80 years, it starts producing fruit 5years after it has been planted out and it reaches full maturity after 15 years, when it can produce asmany as 200 to 600 fruits a year.The essential oil of Citrus limonum is extremely nutritious both for its K-cals and for the phytochemicalsfound in it. N.B. the pressing of the oil must be done cold and without solvents.Limonene induces the formation of apoptotic bodies on BCG-823 gastric cancer cells in a dose-andtime –dependent manner ( 1565 ) and induced significant reductions of hepatocellular carcinomas( 1566 ).Limonene showed anti-angiogenic and pro-apoptotic effects on human gastric cancer implanted innude mice, thus inhibiting tumor growth and metastasis ( 1577 ).N.B. Citrus aurantium bergamia (bergamot orange) should also be investigated for its possibleapoptotic properties on human cancer cells. It grows exclusively in the South of Calabria, Italy.154

Chap.6.f: ElemeneTan P.: Clinical study on treatment of 40 cases of malignant brain tumor by Elemene emulsion injection, Chin. J. Integ.Trad. Western Med, 20, pp.: 645-648, 2000 http://www.mednat.org/cancro/cancro_cervello.pdfOBJECTIVE: To investigate the effect of elemene emulsion injection (EEI) in treating malignantbrain tumor. METHODS: By conducting a retrospective study of 40 patients with brain tumor, 29of malignant glioma and 11 metastatic tumor, who were treated with EEI from January 1994 to May1998. EEI 0.4-1.2 g/d was given to each patient by intravenous dripping or/and intravenous infusionby pumps, and directly injected into carotid artery or infused through a carotid artery catheter withpumps. The total dosage of 6-12 g was given in 2-6 therapeutic courses with an interval of 1-1.5months between courses. The effectiveness of treatment was accessed according to the changes oftumor size, Karnofsky Performance Status (KPS) and survival time of patients. The control groupconsisted of 29 cases of malignant brain tumor (22 of primary and 7 of metastatic) was treated withchemotherapy 2-3 therapeutic courses with an interval of 1-1.5 months between them. RESULTS:(1) In the EEI treated group the mean tumor size was changed from 6.70 cm3 (before treatment) to2.67 cm3 (after treatment), t = 3.02, P < 0.01, it was reduced by 61%; (2) In the EEI treated group 4cases was CR, 26 PR, the total effective rate being 75.0% (95% credibility interval +/- 13.4%),while in the control group, 2 of CR, 10 PR, and the total effective rate 41.4% (95% credibilityinterval +/- 17.9%), the difference between the two groups was significant, chi 2 = 3.867, P < 0.05;(3) KPS decreased in the EEI group from 94.7 scores (before treatment) to 88.2 scores (aftertreatment), the decrement was 6.5 scores (t = 3.5313, P < 0.01); (4) The survival time in the EEItreated group was 25.4 months, and that in the control group was 17.4 months (t = 3.74, P < 0.01).CONCLUSION: Elemene has significant effect on treatment of malignant brain tumor. It couldprolong the high quality survival time of patients and is worthy of further investigation.Chap. 6.g:Other phyto-medicines with an apoptotic or pseudo apoptotic activityMorinda citrifoliaAlso in the fruit of Morinda citrifolia, a shrub from equatorial Africa, South-East Asia, Polynesiaand the Caribbean , known by various names (African bumbo, Indian mulberry, morinda grandis,Lada, Mengkudo, Nhau, Nonu, Noni, Nono) an anthraquinone has been discovered (Damnacanthal)which induced RAS expression and caspase-independent Neuroblastoma cell death: possiblemechanism of spontaneous Neuroblastoma regression ( 1042-1043 ).NOTE: Damnacanthal induces apoptosis in cancer cells, under the stimulation of U.V.A. ( 579 ) andthis could be particularly useful for skin tumors, or for the treatment of internal tumors using fiberoptics, after taking the concentrated juice of the fruit orally, or as an intravenous infusion of thesame active principle (Damnacanthal), if it is pharmacologically bio-compatible for intravenousinfusions.N.B. It might also inhibit cancer growth by restoring the cytoskeleton of the pre-cancerouscells ( 578 ). SEE PDF: Shunji Chi: Oncogenic Ras triggers cell suicide through the activation of a caspaseindependentcell death program in human cancer cells, Oncogene, 1999, Vol. 18, No. 13, pp. 2281-2290http://www.erbeofficinali.org/dati/nacci/allpdf.php155

Abuta cissampelos (Abuta)There is an extensive bibliography on the action of Abuta cissampelos ( 793,810-823 )Abuta contains the alkaloid Tetrandrine, which has been documented to be an analgesic, antiinflammatory,andbebrifuge and has recently been show to have antitumor and antileukemicproperties as well. It also contains an alkaloid called Berberine, which has been documented to behypotensive, antifungal, anti-tumorous, and antimicrobial and is used for the treatment ofcardiacarrhythmia, cancer, candidiasis, diarrhea, and irritable bowel syndrome. Abuta containstropoloisoquinoline alkaloids, pareirubrines A and B, which have been isolated as alkaloids withanti-leukemic properties. In clinical experiments, the bisbenzylisoquinoline alkaloids havedemonstrated to be the anti-inflammatory constituents of Abuta: these alkaloids suppressed theproduction of nitric oxide, a critical mediator in inflammation, which explains some aspects of theanti-infiammatory mechanisms of Abuta.Schinus molle (Brazilian peppertree)There is an extensive bibliography on the action of Schinus molle ( 793,830-838 ).Phytochemical analysis of Brazilian peppertree reveals that the plant contains tannins, alkaloids,flavonoids, steroidal saponins, sterols, terpenes, gums, resins, and essential oils.The essential oil, present in the leaves, bark, and fruit, is a rich source of triterpenes, sesquiterpenes,and monoterpenes, including several novel ones that scientists have not seen before. Many of theplant’s documented biological activities are attributed to the essential oils found in the plant. Thefruit can ontain up to 5% esential oil, and the leaves can contain up to 2% essential oil.In laboratory tests the essential oil as well as a leaf extract demonstrated good to very strongantifungal actions against numerous fungi and even Candida in vitro.The essential oil and leaves have clinically demonstrated in vitro anti-bacterial and anti-microbialactivity against numerous bacteria and pathogens in several studies. In much earlies in vitro tests, aleaf extract of Schinus molle demonstrated antiviral actions against several plant viruses and wasshow to be cytotoxic against 9kb cancer cells.156

Maytenus ilicifolia (Espinheira santa)There is an extensive bibliography on the action of Maytenus ilicifolia ( 793,839-854 ).Espinheira santa contains antibiotic compounds that showed potent antitumor and antileukemicactivities in vivo and in in vitro at very low dosages. Two of these compounds, Maytansine andMayteine, were tested in cancer patients in the USA and South America in 1970s. Althhough therewere some significant regressions in ovarian carcinoma and some lymphomas with Maytasinefurther research was not continued due to the toxicity at the dosages used.Research with the compound Mayteine revealed little to no toxicity, and validated its uses intraditional and folk medicine for various types of skin cancers. Cancer research is still ongoing inSouth America with this compound. In traditional medicine today, an applicatiion of the leaves ofMaytenus is employed as an ointment for treating skin cancer and a decoction is used as a wash forcancers. Although it’s still used in folk medicine for various types of cancer.It’s potent anti-ulcerogenic abilities were demonstrated in a 1991 study that showed that a simplehot water extract of Maytenus ilicifolia leaves was as effective as two of the leading antiulcer drug,Ranitidine and Cimetidine. The same study showed that it caused an increase in volume and pH ofgastric juice. Toxicological studies were also published in 1991 that demonstrated the plant’s safetyof use without side effects.Guazuma ulmifolia (Mutamba)There is an extensive bibliography on the action of Guazuma ulmifolia ( 793,873-883 ).In the first study published, various water and alcohol Guazuma ulmifolia bark extractsdemonstrated weak cardiac depressant and cardiotonic activity, as well as hypotensive, smoothmuscle-relaxant, and uterine-stimulant activities in animal studies. Various leaf and bark extractshave clinically demonstrated in vitro antibacterial and antifungal activity against numerouspathogens in five different studies from 1987 to 1993. It also tested to have active properties againstGonorrhea in vitro in a 1995 study. A weak molloscicidal activity of the bark was documented in a1974 study.A Brazilian research group demonstrated that a dried leaf extract was cytotoxic against cancer cellsin vitro, exhibiting a 97,3% inhibition of cell growth in a 1990 study. Some of the latest research onmutamba has focused on the antioxidants found in the bark and leaves (proanthocyanidins), andtheir ability to interfere with prostaglandin synthetase, a process by which bacteria and pathogensreplicate.Tabebuia impetiginosa, heptaphylla, avellanedae, rosea, serratifolia (Pau d’arco)There is an extensive bibliography on the action of Tabebuia ( 793,884-902 ).The chemical constituents and active ingredients of Tabebuia have been well documented. Its useand reported cures with various types of cancers in the early 1960s fueled much of the earlyresearch. Its anticancerous properties were first attributed to a phytochemical found in the bark andwood called Lapachol. In a 1968 study Lapachol demonstrated highly significant activity againstcancerous tumors in rat. Then, in 1974, the NCI reported that Phase I clinical trials failed to producea therapeutic effect with Lapachol without side effects and discontinued further cancer research.Another research group developed a Lapachol analog in 1975 that was effective in increasing thelife span by over 80% in mice inoculated with leukaemia cells. In a small study in 1980 with ninepatients with various cancers (liver, kidney, breast, prostate and cervix), pure Lapacholdemonstrated an ability to shrink tumors and reduce pain caused by tumors and achieved completeremissions in three of the patients.157

The Phytochemical Database housed at the U.S. Department of Agricolture has documentedLapachol as being anti-abscess, anti-carcinomic, anti-edemic, anti-inflammatory, anti-malarial, antiseptic,anti-tumor, anti-viral, bactericide, fungicide, insectifuge, pesticide, protisticide,respiradepressant, schistosomicide, termiticide, and viricide.Besides Lapachol, Tabebuia contains at least 20 other active constituents that are attrbuted to itsother actions. It has clearly demonstrated broad clinical applications against a large number ofdisease-causing micro-organisms, which hepls explains its wide array of uses in herbal medicine. Itsaction seems to come from increasing oxygen supply at the local level, destroying bacteria, viruses,fungi, and parasites. Its anti-microbial properties were demonstrated in several clinical trials, whichit exhibited strong activity against various gram-positive bacteria and fungi, including Candida,Staphylococcus, Trichophyton, Brucella, tuberculosis(TBC), pneumonia, strep, and dysentery.Tabebuia and its constituents have demonstrated anti-viral properties against various viruses,including Herpes 1 and Herpes 2, influenza, Poliovirus, and Vesicular Stomatitis Virus. Itsantiparasitic actions against various parasites, including malaria, Schistosoma, and Trypanosoma,have been clinically validated. Bark extracts of Tabebuia have demonstrated anti-inflammatoryactivity and have been shown to be successful against a wide range of inflammations.Note1: in 1987 a chemical analysis of 12 commercially available Tabebuia products showed thatonly one product contained Lapachol in trace amounts.Note2: Tabebuia cassinoides (Bignoninaceae): contains Lapachol of the naphthoquinone familyand other naphthos and anthraquinones (as Aloe species), with opposite effects to Vitamin K; it hasanti-bacteria, anti-mycotic and anti-virus effects. The active principles beta-Lapachone anddehydro-alpha-Lapachone have a particular tropism for neoplastic cells and block their oxidativemetabolism, where it accumulates within 6 hours of administration and in very high concentrations.Smilax officinalis (Sarsaparilla)There is an extensive bibliography on the action of this plant ( 793,910-922 )There are many species of Smilax around the world that are very similar in appearance, uses, andeven chemical structure, including Smilax officinalis, Smilax regeli, Smilax aristolochiaefolia,Smilax febrifuga, Smilax sarsapailla, and Smilax ornata.Sarsaparilla vine should not be confused with the tree Sarsaparilla, wich was once used to flavorrootbeer..A Smilax root from Mexico was introduced into European medicine in 1536, where it developed astrong following as a cure for syphilis and rheumatism. Since this time, the Smilax genus has a longhistory of use for syphilis and other sexually transmitted diseases throughout the world. With itsreputation as a blood purifier, it was registered as an official herb in the U.S. Pharmacopoeia as asyphilis treatment from 1820 to 1910. From the 1500s to the present, Sarsaparilla has been used as ablood purifier and general tonic and has been used all over the world for the same conditions,namelt, gout, syphilis, gonorrhea, wounds, arthritis, fevers, coughs, scrofula, hypertension, digestivedisorders, psoriasis, skin diseases, and cancer. The therapeutic dosage is reported to be 1 to 3 gdaily. In the 1950s the antibiotic properties of Smilax were documented. Its effective use as anadyuvant for the treatment of leprosy was documented in a human trial in 1959. Its antiinflammatoryand hepatoprotective effects have been shown in rats, and improvement of appetiteand digestion as well as diuretic actions in humans have also been documented. Sarsaparilla’s blood-purifyng actions were demonstrated when it exhibited the ability to attack and neutralize microbialsubstances in the blood stream.Sarsaparilla has been erroneously touted to contain testosterone and/or other anecbolic steroids. While it is a rich source of steroids and saponins, it has never beenproven to have any anecbolic effects, nor has testosterone been found in Smilax or any other plantsource thus far. No known toxicity or side effects have been documented for Smilax; however,ingestion of large dosages of saponins may cause gastro-intestinal irritation.158

Alcornea castaneifolia, or floribunda (Iporuru)In addition to its anti-inflammatory and pain -relieving properties, an in vitro study in Argentinafound that an extract of Alcornea was antibacterial and effective against a penicillin G-resistantstrain of Staphylococcus aureus, Escherichia coli, and Aspergillus niger ( 923 ). The antiinflammatoryproperties of Alcornea are attributed to a group of alkaloids including Alchorneine,which are found in the bark of Alcornea as well as several other related species of Alchornea ( 924 ).Artemisia speciesAlmost every kind of Artemisia (Sagebrush) contains Tuione, a toxic volatile substance. Inparticular, it is found in Artemisia absinthium (Wormwood), Artemisia pontica (Romanwormwood) but also in other different plants: Salvia officinalis, (Kitchen sage), Thuya occidentalis(Arborvitae), Tanacetum vulgare (Common tansy). Here lies the necessity of taking Salviaofficinalis only as a herbal tea or infusion, and to substantially eliminate Tuja occidentalis andTanacetum vulgare from the healing protocol.But the various types of Artemisia are however useful particularly due to a substance calledArtemisine: in China, a dog, which had been immobilized by a tumor, was cured in five days withinfusions of Artemisina, a substance which is extracted from the stem of Artemisia species. Fromlaboratory experiments it has been noted that Artemisia was able to recognize and eliminate, insixteen hours, all the neoplastic cells in one type of breast tumor which was untreatable withradiation, saving the healthy cells. Artemisina becomes active on cells only when they contain a lotof Iron. Cancer cells normally have a higher than normal Iron level, to allow for the continualreplication of DNA, and a number of receptors for the metal 15 times higher than that of healthycells.N.B. Artemisina has also been used against malaria and it was seen that it does not have anyside effects( 723 )..Larrea divaricata (Zigophyllaceae):it contains nor-didehydroguairetic acid. It has an anti-oxidant and bacteriostatic activity. It stopsaerobic and anaerobic glycolysis, inhibiting the action of cancerogenous substances. It would seemto be very effective on gastro-intestinal tumors.Hypericum perforatum (Hypericaceae):contains hypericine ( 724 ), which has also been indicated for brain tumors, taking into account itsimmune-stimulating ability.Capsella bursa pastoris Cruciferae):hemostatic, anti-metrorrhagia and oxytoxic compounds. It has an anti-neoplastic activity with amechanism which is not clear.159

Annona muricata (Graviola)Its still being studied ( 725-735 ).Several studies by different researchers demonstrated that the bark aswell as the leaves had hypotensive, antispasmodic, vasodilator, smooth muscle-relaxant, andcardiodepressant activities in animals. Researchers reverified graviola leaf’s hypotensive propertiesin rats again in 1991. Several studies over the years have demonstrated that leaf, bark, root, stem,and seed extracts of Annona muricata are antibacterial in vitro against numerous pathogens, andthat the bark has antifungal properties. Annona muricata seeds demonstrated active antiparasiticproperties in a 1991 study, and a leaf extract showed to be active against malaria in two otherstudies, in 1990 and 1993. The leaves, root, and seeds of Annona muricata demonstratedinsecticidal properties, with the seed demonstrating strong insecticidal activity in an early 1940study. In a 1997 clinical study, novel alkaloids found in Annona muricata fruit exhibited antidepressiveeffects in animals. Much of the recent research on Annona muricata has focused on anovel set of phytochemicals found in the leaves, seeds, and stem that are cytotoxic against variouscancer cells. In a 1976 plant screening program by the National Cancer Institute, the leaves andstem of Annona muricata showed active cytotoxicity against cancer cells, and researchers have beenfollowing up on this research ever since. Two separate research groups have isolated novelcompounds in the seeds and leaves of the plant that have demonstrated significant anti-tumorous,anti-cancerous, and selective toxicity (apoptosis) activity against various types of cancer cells; theresearch groups have published eight clinical studies on their findings.One study demonstrated that an isolated compound in Annona muricata was selectively cytotoxic(apoptosis) to colon adenocarcinoma cells, showing that it had 10.000 times the potency ofAdriamycin, a leading chemotherapy drug.Soncus oleracues and Soncus arvensis (Compositae):considered effective against breast carcinomas.Cynara scolymus [Compositae cinaraceae] (artichoke):contains Cynaropicrin, which has an anti-neoplastic activity (apoptosis). It may contain othermolecules with an anti-neoplastic activity or at least have curative properties against deficiencypathologies of various types, including tumors. Unfortunately, the precious plant is already beingsubjected to irreversible genetic modification (GMO) ( 808 ).Euphorbia heterodoxa (Euphorbiaceae):a Brazilian plant the juice of which, called “alvelos” would seem to be effective against skintumors, carcinomas and sarcomas.Cetraria islandica (Parmeliaceae):similar to Cetraria gryophora and umbilicaria it has anti-tumoral activity, but it is not known onwhat basis.160

Some studies have been carried out recently on the metanolic extract of the flowers of Hypericumperforatum, on the bark of Betula alba, on Vaccinium vitis idaea and on many other herbalproducts, and have found a lot of evidence of selective action on certain types of human and animaltumors. Much of this data is confidential.Recently 200 herbs have been catalogued, to be used as herbal extracts, both as an anti-oxidative(SEE chap.3) and an immune-stimulant (SEE chap.9), and especially as a potential apoptotic orpseudo-apoptotic activator, on the basis of current ideas in the world herbarium (about 25,000plants).Because most of these extracts come from flowers, according to the author the following could bejustified:1) The production of honey from one flower based on these extracts, where possible.2) The production of mixed seeds and pure organic honey, for example of Acacia.3) The production of seeds to then be germinated (recipient full of water which is rich inmineral salts, drained and then made to germinate).4) The production of mixed seeds with sesame oil (Sesamum indicum) according to the ancientIndian tradition: it is the type of oil most used in the Ayurvedic tradition, because it absorbsthe different herbal properties used in Indian medicine very well, thus helping gastrointestinaldigestion; this particular oil must be pressed cold. On the other hand, it has a highpercentage of protein (25%), and its use is therefore to be evaluated.There are about 200 plants considered by the author for their bio-chemotherapy activity.1) Acalypha indica2) Acorus calamus3) Actinidia chinensis4) Adiantum capillus veneris5) Ailantus glandulosa6) Ajuga reptans7) Ajuga piramidalis8) Albizzia lebbek9) Alchimilla alpina10) Alchimilla vulgaris11) Allium sativum12) Alpinia oxyphylla13) Althaea officinalis14) Annona muricata15) Annona squamosa16) Antennaria dioica17) Antyllis alpestris18) Apium graveolens19) Aquilaria agallocha20) Aralia racemosa21) Arctium lappa22) Argemone mexicana23) Argyreia speciosa (o Lettsomia nervosa)24) Artemisia abrotanum25) Artemisia dracunculus26) Asparagus cochinensis161

27) Asparagus racemosus28) Astragalus membranaceus29) Atractylodes ovata30) Azadirachta indica31) Bacopa monnieri32) Bambusa arundinacea33) Betula alba34) Boswellia carterii35) Boswellia serrata36) Buxus sempervirens37) Caesalpinia sappan38) Campanula latifolia39) Capparis spinosa40) Capsicum frutescens, fasciculatum, or annuum41) Cardamine pratensis42) Carlina acaulis43) Carpinus betulus44) Cassia angustifolia45) Ceanothus americanus46) Celastrus scadens47) Cerastium alpinum48) Chimaphila umbellata49) Chondrus crispus50) Cinchona calisaya51) Cinchona succirubra52) Cinnamomum zeylanicum53) Cirsium spinosissimum54) Citrus aurantium bergamia55) Citrullus colocynthis56) Citrus limonum57) Coscinium fenestratum58) Crataegus oxyacantha59) Crataegus monogyna60) Crocus sativus61) Cupressus lusitanica62) Curcuma longa63) Curcuma zedoaria64) Draba aizoides65) Drinaria fortunei66) Drosera anglica67) Drosera intermedia68) Drosera rotundifolia69) Echinacea angustifolia70) Echinacea pallida71) Echinacea purpurea72) Eclipta alba73) Emblica officinalis74) Epilobium angustifolium75) Epilobium parviflorum76) Equisetum arvense77) Erithrea antaurium162

78) Eucalyptus globulus79) Eupatorium perfoliatum80) Eupatorium purpureum81) Eurycoma longifolia82) Euspongia officinalis83) Ferula communis84) Frangula alnus85) Galphimia glauca86) Galium aparine87) Gordonia axillaris88) Gardenia jasminoides89) Gentiana germanica90) Geranium robertianum91) Glechoma hederaceum92) Glycyrrhiza glabra93) Gnafalium supinum94) Goniothalamus species95) Grindelia camporum96) Grindelia squarrosa97) Helianthus annuus98) Jieracium pilosella99) Holarrhena antidysenterica100) Hibiscus sabdaiffa101) Houttuynia cordata102) Hydnophytum formicarum103) Hypericum perforatum104) Hypericum richeri105) Hypoxis hemerocallidea106) Hyssopus officinalis107) Lamium album108) Lapsana communis109) Larrea divaricata110) Larrea mexicana,111) Laurus nobilis112) Lepidium meyenii113) Leucanthemopsis alpina114) Lonicera caprifolium115) Lycopodium clavatum116) Lysimachia nummularia117) Luffa operculata118) Mahonia aquifolium119) Malva silvestris o vulgaris120) Momordica charantia121) Marasdenia cundurango122) Marrubium vulgare123) Medicago sativa124) Melaleuca alternifoglia125) Melissa monarda126) Melissa officinalis127) Meum mutellina128) Mimosa species163

129) Momordica charantia130) Morinda citrifolia131) Moringa pterygosperma132) Myrica cerifera133) Myristica fragrans134) Myristica sebifera135) Myroxylon balsamum136) Myrtus communis137) Nelumbo nucifera138) Nepeta cataria139) Nerium oleander140) Ochrosia elliptica141) Ocimum basilicum142) Ocimum sanctum143) Ocimum tenuiflorum144) Pedicularis rostrato-capitata145) Pereskia bleo146) Peucedanum ostruthium147) Picramnia antidesma148) Pimpinella major149) Pimpinella saxifraga150) Phyllanthus orbicularis151) Phyllanthus urinaria152) Plantago major153) Polygala senega154) Polygonum aviculare155) Polygonum cuspidatum156) Primula hirsuta157) Primula officinalis158) Primula veris159) Prunus amygdalus160) Prunus armeniaca161) Prunus avium162) Prunus nigra163) Prunus persica164) Prunus spinosa165) Pulmonaria angustifolia166) Pulmonaria officinalis167) Quercus robur168) Rhamnus sagrada169) Rhamnus purshiana170) Rheum officinale171) Rheum palmatum172) Rhodiola rosea173) Rosmarinus officinalis174) Rubia cordifolia175) Rubia peregrina176) Rubia tinctorium177) Rumex acetosa178) Rumex crispus179) Salvia miltiorrhiza164

180) Salvia officinalis181) Sambucus nigra182) Saxifraga aizoides183) Saxifraga oppositifolia184) Scutellaria baicalensis185) Sempervivum montanum186) Serenoa repens187) Sida cordifolia188) Smilax sarsaparilla189) Smilax utilis190) Solanum lyratum191) Sophora flavescens192) Stachys arvensis193) Sticta pulmonaria (o Lobaria pulmonaria)194) Streptocaulon juventas195) Sutherlandia frutescens196) Tabebuia cassinoides197) Tabebuia impetiginosa198) Taraxacum officinalis199) Tephorosia purpurea200) Terminalia chebula201) Thalictrum acutifolium202) Tinospora cordifolia203) Tribulus terrestris204) Trifolium pratensae205) Trifolium rubeus206) Trigonella foenum graecum207) Thymus serpillum208) Thymus vulgaris209) Ulmus rubra210) Uncaria guianensis211) Uncaria tomentosa212) Urtica dioica213) Vaccinium vitis idaea214) Verbascum densiflorum o thapsus215) Viola tricolor216) Xantoxilum fraxineum165

Chapter 7 :vitamin B 17 (Laetrile)Vitamin B17 was thoroughly studied by Japanese researchers in the early 1970s. Vitamin B17 isfound especially in apricot (Prunus armeniaca) kernels.It is also found in the bitter seeds of wild almonds (Prunus amygdalus), of cherries (Prunus avium),of plums (Prunus domestica), of peaches (Prunus persica), of blackthorns (Prunus spinosa), ofacerolas (Malpighia punicifolia), of quinces (Cydonia oblonga), as well as in the seeds and/or pulpof many other fruits.This vitamin is very useful for cancer therapy. Indeed, it takes advantage of cancer cell metabolism,which is different from healthy cell metabolism in human beings.Neoplastic cells, and especially anaerobiotic neoplastic cells, have a high concentration of beta-Glucosidase, without Rhodanese. Therefore, they immediately phagocyte vitamin B17, and divide itby hydrolysis into two poisons: benzaldehyde and cyanide ions. On the contrary, healthy cells arenormo-oxygenated and rich in Rhodanese, so they quickly convert these two poisons into benzoicacid and thiocyanates respectively. Both of them are harmless for healthy cells; actually, they areuseful for them. According to Kanematsu Sugiura, a Japanese researcher, beta-Glucosidase is foundin the cells of breast, stomach, womb, mesentery and gullet cancer, in much higher concentrationscompared to healthy cells. On the contrary, the Rhodanese enzyme is not present in cancer cells ( 514,515,774-787 ).The modern history of vitamin B17 started in 1830, when two French scientists, Roubiquet andBontron-Chariand, purified for the first time a vitamin later called Amygdalin or vitamin B17 ( 1187 ).Seven years later two German scientists, Von Liebig and Woehier, discovered that this vitamincould be found in all fruit seeds (apart from citrus fruits) and could be divided into Cyanide ions,Benzaldehyde and Glucose by only one specific enzyme.The use on human beings for medical purposes and cancer therapy followed shortly after. In 1845,fifteen years after the first French scientific experiences, the French scientific journal “GazetteMedicale de Paris”, (1188) and afterwards the German journal “Journal für die Chirurgie undAugenheil-kunde”( 1189 ), described the first case of metabolic therapy with vitamin B17 to “curecancer”, created by Russian doctor Inosmetzeff, professor at the Imperial University of Russia inMoscow. Therapy was performed on a twenty-one-year-old boy affected by cancer, and consistedof 46 grams of Amygdalin administered for 3 months. Inosmetzeff had also cured a 48-year-oldwoman with extended metastases due to womb cancer. In 1845 this woman was still alive, 11 yearsafter metabolic therapy with Amygdalin. In both cases, Inosmetzeff said that he never noticed anyside effects with vitamin B17.This vitamin was only used again for cancer therapy after more than a century, that is in 1950, whenUS researcher Ernest Krebs started using vitamin B17 again. After boiling it, evaporating it inalcohol, and then settling it in small white crystals, he called the result “Laetrile”.166

The term “Laetrile” is the acronym for “LAEvomandeloniTRILE-glucoside”. It is almost the sameas Amygdalin (which is naturally present in fruit bitter seeds). The only difference is in chemicalstructure: Laetrile has two molecules of glucose, Amygdalin has more. Indeed, the chemicalstructure of Laetrile is D-1 mandelonitrile–beta-glucuronide, while for Amygdalin it is D-mandelonitrile-bi-glucoside.There are at least a dozen other cyanogenetic glucosides (nitrosilides) similar to Amygdalin, thatcan be found in vegetables, fruit (including lemons), cassava, legumes and cereals ( 1190 ).Vitamin B 17 is a stable, chemically inert molecule, and it is not noxious if taken in the rightquantity under a doctor’s supervision. The initial recommended dosage in adults is 4-5 bitter seedsper day for apricot bitter seeds (quantity has to be higher or lower if seeds are of a different fruit)for the first week. In the following week, the doctor can decide whether dosage can be increased ordiminished. The values that have to be reached must be carefully calculated according to thefollowing parameters: the biological half-life of vitamin B17, urine analysis (the presence ofSodium Thiocyanate and hippuric acid in certain quantities could mean that the quantity of seedstaken is too high), the patient’s hematic and body mass, the patient’s good or bad liver, kidney (andother organs’) function, the possible massive colliquation of cancer mass with possible death due toirreversible kidney failure, etc…The pharmaco-cynetics of vitamin B17 are complex and must be taken into account. In medicaland/or phitotherapic literature, episodes of deadly poisoning of children have been reported. Deathoccurred after they ate food that was particularly rich in vitamin B17, such as peculiar berries,traditionally not eaten and therefore extremely interesting for cancer therapy, or bitter almondseeds, which are notoriously richer in vitamin B17 than apricot bitter seeds. Death in children iseasier because the concentration of vitamin B17 is higher in a smaller body. Moreover, their livermass is smaller: this organ is essential to detoxify blood from vitamin B17. Finally, liver enzymesin children could be less functional.Treatment has to be interrupted from time to time under a doctor’s supervision. Seeds must bechewed very well or previously ground. Therapy has to be stopped immediately if sickness arises.Seeds must never be taken all together, but during the whole day. It is better to eat them on a fullstomach, in order to avoid the partial hydrolysis of vitamin B17 by hydrochloric acid. It is forbiddento take more than six apricot bitter seeds in one hour, even if health conditions are good; as far aspeach seeds are concerned, a dosage of no more than half seed per one hour can be taken.Vitamin B17 poisoning is not the only possible one. Other natural vitamins, too, can cause death iftaken in excess. For instance, medicine books still report an episode that took place at the beginningof the 20th century. A group of arctic explorers died because of vitamin A poisoning: they had eatenhuge quantities of polar bear liver, that they had taken for survival.The only vitamin that seems not to cause poisoning is said to be vitamin C. It can be taken inquantities higher than 50 grams per day.Back to vitamin B17, Krebs discovered that this vitamin reacts to enzyme Beta-glucosidase. Thelatter is found in many tumors, and is virtually absent in healthy cells. In the reaction, the enzymesplits the innocuous vitamin B17 into two powerful poisons: Cyanide ions and Benzaldehyde. Thelatter is a strong painkiller. These two substances are produced in small quantities by cancer cellsthemselves, and combine in cancer cells producing an extremely toxic substance that kills cells in asort of pseudo-apoptosis.167

Small quantities of this poison can still be active even after cancer cells died and can go intocirculation, cancer generally having many blood vessels.On the contrary, healthy cells have another enzyme, called Rhodanese. It is found in cells inquantities that are inversely proportional to those of Beta-glucosidase. If vitamin B17 comes intocontact with healthy cells, Rhodanese neutralizes Cyanide ions and oxidizes Benzaldehyde. Twoproducts are obtained: Thiocyanate and benzoic acid, which are good nutrition for healthy cells. Ifthese two products are in excess, they are eliminated through the urine.It is clear then that the enzyme Beta-glucosidase produces Cyanide ions from nitriloside food.Notice that Cyanide ions have to be freed from vitamin B17 or from Laetrile. Cyanide ions are notfound freely in food: they are only produced in cancer cells, because the specific enzyme for this(Beta-glucosidase) can only be found in cancer cells.In 1947, Fishman and Aniyan wrote in the important medical journal Journal Biol. Chem. ( 1191 ):“…Tissue excised from malignant noeplasms (cancers) of various organs, including breast, uterus,stomach, abdominal wall and esophagus were found to contain 200 to 3600 percent more betaglucosidaseactivity than uninvolved adjacent tissue. Metastases to lymph nodes from cancersoriginating in various organs contained beta-glucosidase in higher concentrations than theuninvolved lymph nodes”. http://www.mednat.org/cancro/FISHMAN%201947.pdfIn the same year, they wrote in the notorious journal Science ( 1192 ): “…high Beta-glucosidase isprobably a characteristic feature of cancer cells”.In his book “Nitrilosides (Laetriles)”, pages 189-204, Krebs writes:http://www.mednat.org/cancro/Nitrilosides_Plants_Animals.pdf“In addition to their high levels of Beta-glucosidase, malignant lesions are characterised by agenerally profound deficiency of Rhodanese, as was reported by Homberger, Mendel, Rodney andBowman. Rosenthal reported an 80% decrease in Rhodanese in cancerous liver tissue, and asimilar decrease was found in the leukemic invasion of tissues”( 1187 ).Researcher James South explains the essential biochemistry of what happens when a person eatsnitriloside food or takes vitamin B17 in pharmaceutical form, either as Laetrile or as Amygdalin:“…These two properties of cancel cells – an excess of Laetrile-splitting Beta-glucosidase and adeficiency of cyanide-detoxifiying Rhodanese – are presumed to provide the explanation of bothwhy Laetrile kills cancer cells, and why it is preferentially split by cancer cells into Cyanide ions,Benzaldehyde and sugar. They will then be poisoned, since cancer cells lack the Cyanidedetoxifyingenzyme Rhodanese. If some Cyanide “spills out” from the cancer cells, adjacent normalcells will then be able to detoxify it through their Rhodanese enzymes.” ( 1187 ).http://www.mednat.org/cancro/JAMES_SOUTH.pdfIf quantities do not exceed liver (and other organs’) function of purifying blood from this poison, itis the doctor’s task to assess how the metabolic therapy is going from blood and urine tests andfrom the patient’s general check-up.The Rhodanese enzyme destroys hydrocyanic acid and produces a non-toxic substance:Thiocyanate. As Oke notes:“…Rhodanese is widely distributed in all the tissues with the highest concentrations in the liver.Detoxification can therefore take place in all parts of the body, but with the liver as the chief site.168

When hydrocyanic acid (Cyanide) is converted to thiocyanic acid (Thiocyanate) there is a 200-foldreduction in toxicity”( 1190 ). http://www.mednat.org/cancro/OKE.pdfWhen Beta-glucosidase destroys Laetrile, Benzaldehyde and Cyanide ions are released in cancercells.Several studies on humans used Benzaldehyde itself as a drug against cancer ( 1193,1194 ). In 1980-1985 Kochi wrote: “ …no toxic effects were reported, including hematologic or biochemicaldisorders, even when Benzaldehyde was repeatedly administered for long periods.”http://www.mednat.org/cancro/benzaldehyde_derivative.pdfTatsumura used an average total dose of 393 grams of a substance similar to Benzaldehyde, thatsubsequently changed into Benzaldehyde, and obtained a positive reaction rate of about half the 24patients who were given treatment:“…Careful monitoring showed no toxic action of the drug at these large doses. Complete necroticliquefaction of tumour was seen in 2 of 3 cases in which histological examination wasfeasible”( 1195 ). http://www.mednat.org/cancro/TATSUMURA.pdfDuring the Seventh International Congress of Chemotherapy in Prague, in 1971, Dean Burk said:“In vitro tests with Ehrlich ascites carcinoma (a type of cancer cell culture) revealed that, wherecyanide alone killed one percent of the cells and Benzaldehyde alone killed twenty percent, acombination of the two was effective against all the cells. Amygdalin with Beta-glucosidase addedalso succeeded in killing 100 percent of the ascites tumor cells, due to the same two chemicals”( 1187 ).But Krebs soon realized that he had clashed with huge economic interests. Chemo-pharmaceuticalmultinationals could not obtain a registration nor have exclusive rights on vitamin B17. Thus, theybegan a long defamatory campaign against apricot bitter seeds, and they convinced the wholeAmerican population that these are allegedly dangerous.At the moment, cancer treatment with Laetrile is forbidden by law in the USA, even if under adoctor’s supervision. That is why dozens of thousands of American citizens get treatment inexpensive private hospitals just beyond the Mexican border, in Bahamas, and in other places, wherethey officially go “on holiday”.For instance, doctor Francisco Contreras, the current managing director of the Oasis of Hopehospital in Tijuana, Mexico, treated more that 60,000 patients with a vegetarian therapy and vitaminB17 in 35 years of activity ( 1187 ). http://www.mednat.cancro/Contreras.pdfDoctor Ernesto Contreras has been using Laetrile since 1963, and thinks that“…The majority of most frequent cancers, such as lung, breast, colon, ovarian, stomach,esophagus, prostate cancer, and lymphoma, can improve dramatically with Laetrile” ( 1187 ).169

Case historyAmygdalin taken orally has been known to be a poison since ancient times, though amygdalin-laden blackand brown bitter seeds were described as antitumor agents in the pharmacopeia of ancient China ( 1497 )Egyptian, Greek, Roman and Arabic physicians also used amygdalin to treat tumors ( 1498 ).In a study conducted in 1958, Prof Marco Tasca, head of the radiology department of the Civil Hospital in Sanremo,treated 21 Italian terminally ill patients – 3 suffering from seminomas, 4 from breast cancers, 1 from womb cancer, 2from laryngitis cancers, 7 from lung cancers, 1 from cancer of the oesophagus, 2 from stomach cancers, 1 fromHodgkin’s disease – with intramuscular injections of Laetrile. He noticed that patients showed good drug tolerance,their clinical conditions improved during the entire treatment period and only one month – on average – after theinterruption of the therapy the neoplastic pathology resumed its progression. He pointed out only two complications:hemorrhage and icterus. The former probably caused by necrotic eschars coming off the tissues, the latter induced by adirect toxic action on hepatic cells, which rarely happens though (5% of his case histories). The article is available inPDF format ( 1373 ) at http://www.fiocco59.altervista.org/images/tasca.pdf or http://www.mednat.org/cancro/tasca.pdf.In the 1966 report, Proceedings of the Ninth International Cancer Congress, Rossi cites a ten-yeartrial in Europe involving 150 patients that found "50 percent of all cases in treatment showedobjective improvement" and concluded that laetrile was "an extremely useful chemotherapeuticdrug."( 1382 ) http://fiocco59.altervista.org/vitamina_b_17.htmIn 1994, professor Binzen published the results he obtained treating patients with Laetrile between1974 and 1991. His case history included 180 patients with primary cancer (with no metastasis andlimited to only one organ or tissue). 131 patients were still alive in 1991, when the report waspublished. At that time, 58 patients had been followed for 2 to 4 years, while 80 of them had had amedical follow-up for 5 to 18 years. Out of the 42 patients that had died by 1991, 23 had died fromcancer, 12 from “unrelated causes” and 7 of “unknown causes” (Binzel E.P.: “Alive and Well”).http://www.mednat.org/cancro/ALIVE_AND_WELL.pdfAmong patients with metastasis, 32 out of 108 had died from their disease, 6 from “unrelatedcauses” and 9 from “unknown causes”. Out of the 61 patients that were still alive in 1991, 30 hadhad a medical follow-up of 2-4 years, 31 had been followed for 5-18 years.Doctor John A. Richardson’s case history of 1976 reports over 6,000 cases that show a positiveeffect of vitamin B17 against cancer. ( 1187 )There are 4,800 cases reported and carefully studied by doctor Ernesto Contreras. Those wereselected among 10,000 case sheets collected in 14 years of experiences with Laetrile.Doctor Paul Wedel from Oregon reported about 4,000 cases of metabolic treatment. He survivedcancer himself with vitamin B17 and a diet similar to the gersonian one ( 1187 ).1,000 cases were reported by doctor Manuel Navarro of Santo Tomas University in Manila, thePhilippines. The Mexican government is even monitoring about 100 patients that are being treatedwith metabolic therapy and vitamin B17, under the guidance of doctor Mario Soto de Leon, medicaldirector of the Cydel Clinic in Tijuana ( 1187 ).In Germany, doctor Hans Nieper reported about 1,000 cases. (http://www.mwt.net/~drbrewer )It is interesting to notice that cases such as that of Mr. Glen Rutherford from Kansas, who healedcompletely in Tijuana, are recorded in tribunal archives as “cures” ( 1187 ).170

Note of doctor Giuseppe Nacci (author of this book) : in ALLEGATED see Morrone J.A.: Exp.Med. Surg. 20, pp.. 299-308, 1962.Title: Preliminary Report of 10 cases treated with Laetrilehttp://www.mednat.org/cancro/morrone.pdfALLEGATED: Morrone J.A.: Exp. Med. Surg. 20, pp.. 299-308, 1962.Title: Preliminary Report of 10 cases treated with LaetrileCase 1.: W.L. age 62, female, married, housewife, weight 118 lb., height 62 in., blood pressure 144/95 mm. Diagnosisadenocarcinoma of both breasts with metastases to the skull, pelvis and spine. There was bilateral inguinal adenopathy.History of bilateral mastectomy, eighteen years apart, fallowed by deep X-ray. Urinalysis and hemotology negative.During the last six months the patient had suffered from constant excruciating pain in the back, entire spinal region,pelvis, thighs and legs. She was unable to lie down and tried to sleep in a chair. Repeated doses of codeine and otheranalgesics every two or three hours were required. Laetrile 1 gm was injected intravenously. In five minutes the systolicblood pressure dropped 12 mm but there were no other apparent effects. The following day the patient walked into myoffice without aid and reported that she had slept well with very little pain, that she needed less codeine, and that herappetite was good. Her general appearance was greatly improved.An injection of Laetrile 1 gm was repeated. The systolic blood pressure fell 10 mm, but there were no apparent sideeffects. After ten minutes she said that pain was relieved completely and stepped down from the examining tablewithout help. In a period of one month she received six injections of Laetrile, four of 1 gm and two of 2 gm. In eachinstance there was a prompt fall of blood pressure, average 10,4 mm, range 8-12 mm.During the period of treatment the patient returned to her house-work, was almost free from pain, discontinued codein,took non analgesics other than 10 grains of aspirin at bedtime or during the night, and slept well. Her morale wasexcellent, her appetite good, and she gained 3 ½ lb. At the last examination she reported that she was completely freefrom pain. There were no apparent adverse effects from any of the injections. As of May 1, 1962 the hemogram showeddistinct improvement in red blood cell count and haemoglobin, with no adverse changes. Urinalysis was negative.Case 2.: J.S., age 74, male, married, pattern maker, weight 163 lb., height 62 in., blood pressure 188/100 mm. Diagnosisinoperable carcinoma of the left lung with metastasis to the mediastinum. Urinalysis and haematology negative.During the last six months the patient complained of cough, constant chest pain, dyspnea, blood-tinged expectoration,anorexia, and loss of weight (15 lb.) . A X-ray revealed a mass in the left side of the chest suggestive of a neoplasm.Bronchoscopy and a biopsy established the diagnosis of carcinoma of the lung. Exploratory thoracotomy showedextensive carcinoma of the left lung with metastases and many perforations in the pleura, diaphragm, aorta, pericardiumand mediastinum. The condition was considered inoperable.Pain was so constant and severe that the patient took meperidine hydrochloride and codeine every two or three hours.When interviewed, he had such great difficulty in talking and breathing that his wife had to give the history.Physical examination revealed icteric sclerae, pallid conjunctivae, sluggish reflexes, enlarged and tender cervical andsupraclavicular glands, dullness and moist rales over the life side of the chest, and edema of the ankles extending up tothe knees.Laetrile 1 gm was injected intravenously. In five minutes the systolic pressure dropped 28 mm but there were no signsof shock or other adverse effects. Three days later the patient reported that the pain had been less severe since theinjection but that he had suffered for two days from pain in the left shoulder and side of the chest. Analgesics were stillrequired. After the second intravenous injection of Laetrile 1 gm, the systolic blood pressure fell 15 mm, but there wereno side effects other than burning to the office unassisted. Pain, dyspnea and edema were considerably diminished. Hiscolor and general appearance were considerably improved.In a period of seven weeks he received sixteen injections of Laetrile, seven of 1 gm, six of 1,5 gm, and three of 2 gm.There was a prompt fall of blood pressure following the injections, ranging from 8 to 28 mm. Pain was reduced andappetite improved but there was no weight gain. He was able to discontinue use of meperidine hydrochloride andcodeine. There were no apparent adverse effects from the injections as shown by the before and after hemograms andurinalyses.Case 3.: J.C., age 40, female, married, housewife, weight 113 lb., height 61 in., blood pressure 140/90 mm. Diagnosisinfiltrating carcinoma of the left breast invading the lymph nodes at all levels of the axilla, with metastases to the liver.Radical mastectomy and deep X-ray therapy. Urinalysis and haematology negative.For the last six months she suffered from very severe pain in thre abdomen and back. Meperidine hydrochloride,morphine and opium were required for relief.Laetrile 1 gm was injected intravenously. In five minutes the systolic blood pressure dropped 10 mm but there were noother apparent effects. She returned the following day and reported no relief of pain.An intravenous injection of Laetrile 1 gm, was repeated, following which the systolic blood pressure dropped 12 mm.There was considerable reduction of pain and appetite improved after this injection. In a period of four weeks shereceived twelfe injections of Laetrile, ten of 1 gm, and two of 1,5 gm. Pain was relieved almost entirely and only a171

single dose of narcotic drug at bedtime was required. Morale and appetite were improved but there was no gain inweight. There were no apparent adverse effects from the injections. Comparison of before and after hemograms showedimprovement in the red blood cell count and haemoglobin following Laetrile therapy.Case 4.: J.F., age 38, female, married, housewife, weight 155 lb., height 62 in., blood pressure 160/90 mm. Diagnosisadenocarcinoma of left breast with carcinomatosis. Mastectomy, deep X-ray therapy and castration. Urinalysis andhaematology negative. The patient complained of agonizing pain in her spine, chest, pelvis, legs, arms and head. X-rayvisualization confirmed the diagnosis of disseminated metastases. Adenopathy was present. Codeine, meperidinehydrochloride and opium were required to control the pain. Laetrile 1 gm was injected intravenously. After fifteenminutes the systolic blood pressure rose 3 mm. There were no apparent side effects. On the following day pain wasreduced, appetite improved, and the general condition was somewhat better. A second intravenous injection of Laetrile1 gm was given. In five minutes the systolic blood pressure dropped 16 mm but there were no apparent side effects.Three days later the patient reported that the pain was considerably less and she required a minimum dosage of opiatesfor relief. In a period of eighteen days she received eight injections of Laetrile, five of 1 gm, two of 1,5 gm, and 1 of 2gm.During the period of medication she showed progressive improvement and suffered very little pain. Opiates were nolonger required. Morale was excellent. There were no apparent adverse effects from the injections. Comparison ofbefore and after hemograms showed improvement in the red blood cell count and haemoglobin following Laetriletherapy.Case 5.: R.F., age 20, male, single, premedical student, weight 200 lb., height 69 in., blood pressure 114/70 mm.Diagnosis malignant lymphoma, type Hodgkin’s. Condition started as enlarged cervical gland, diagnosis on biopsy.Urinalysis negative, haemoglobin 11 gm/100 cc. Deep X-ray therapy was employed. The patient complained ofweakness, dizziness, and pain in the axillae and groin. The cervical, axillary and inguinal glands were palpablyenlarged. The conjugativae and sclerae were pale and icteric. Laetrile 1 gm was injected intravenously. In ten minutesthe systolic blood pressure dropped 6 mm, but here were no other apparent effects. Four days later the patient reportedthat he felt more active, had a better appetite, and had suffered no ill effects. An injection of Laetrile 1 gm was repeated.The systolic blood pressure dropped 4 mm in ten minutes, no other apparent effects. In a period of four and a halfmonths he received nineteen injections of Laetrile, five of 1 gm and fourteen of 2 gm. During the period of medicationthe pains in the neck and groin ceased and the adenopathy disappeared. The patient felt euphoric and his generalappearance was considerably improved. There were no apparent adverse effects from the injections. The blood pictureimproved after Laetrile therapy.Case 6.: L.D., age 37, female, single, draftsman, weight 190 lb., height 66 in., blood pressure 280/110 mm. Diagnosisinfiltrating adenocarcinoma of left breast. Both her mother and sister had died of cancer. History of radical mastectomy.Metasteses in left axilla broke down, producing multiple sinuses. The principal complaints were severe pain in the leftside of the chest, necessitating the use of codeine, and a foul odor from the discharging sinuses. To control herdistressing cough it was necessary to prescribe meperidine hydrochloride and opium for use on alternate days. The leftshoulder and arm were swollen and painful. The skin was glistening red. The circumference of the left mid-armmeasured 19 ½ in., as compared with 13 in. for the right. Adenopathy was present in the entire left axillary andsupraclavicular areas, both sides of the neck, and in the right breast. The liver was palpable and tender. Both sides of thechest were tender and especially painful on coughing.Laetrile 1 gm was injected intravenously. In five minutes the systolic blood pressure dropped 38 mm but there were noapparent other effects. On the following day she received a second injection. Pain and cough diminished and there wasless discharge from the axillary sinuses. However, she felt a sense of heat and itching in the operative area. After thethird injection pain was relieved completely and the fetor disappeared. After the fourth injection, the drainage ceasedcompletely and the area was odourless. Multiple crusts covered the healing sinuses. Induration and inflammation werealmost completely gone. The texture of the skin of the left arm had returned to normal. In a period of five months shereceived fifty injections of Laetrile, nine of 1 gm, thirty-nine of 2 gm, and two of 2,5 gm. The immediate hypotensiveresponse was easily controlled when phenylephrine hydrochloride 0,3 mg was used simultaneously with Laetrile.During the period of treatment the patient returned to work. Pain and cough disappeared. The discharge from themetastatic sinuses ceased and there was no more fetor. The circumference of the left mid-arm was reduced from 19 ½in., to 17 in., an indication of less tumefaction. Narcotics for relief of pain and cough were no longer required. Therewere no apparent adverse effects from any of the injections. In this case treatment with Laetrile was continued fromJuly 7, 1961 until May 1962. In the extended period of ten months the patient received 133 injections, twince a week oroftener. Comparison of before and after hemograms showed definite improvement in the red blood cell counts andhaemoglobin. Adenopathy and tumefaction regressed to a considerable extent.Case 7.: G.P., age 21, male, single, college student, weight 149 lb., height 70 in., blood pressure 110/70 mm. Diagnosismalignant lymphoma, Hodgkin’s type. Urinalysis and haematology negative. A growing mass in front of the right ear,which returned four years after its initial appearance and recession, was removed and found to contain multinucleatedgiant cells typical of Hodgkin’s disease. There was a hard, tender, enlarged lymph node in the mid-sternocleidomastoid172

egion measuring 3 x 2 cm. Urinalysis and haematology were negative. Laetrile 1 gm was injected intravenously. Thesystolic blood pressure dropped 4 mm, but there were no apparent side effects. Three days later the enlarged gland wassmaller, softer, and less painful. By the sixth day all pain had ceased. In a period of four months he received twentyseveninjections of Laetrile, ten of 1 gm, and seventeen of 2 gm. There were no side effects. One injection, madedirectly into the tumor mass, was followed by itching and local tenderness. During the period of treatment the patientreturned to college. Pain was absent, appetite good, weight icreased 13 lb., and his appearance was excellent. The bloodpicture improved under Laetrile therapy.Case 8.: A.T., age 66, male, married, fireman, weight 120 lb., height 68 in., blood pressure 188/98 mm. Diagnosisinoperable carcinoma of the prostate with possible metastasis to the liver. Hemoglobin 10 gm/100 cc. The patientcomplained of nicturia, hematuria, nausea, vomiting, and severe pain in the groin and thighs. Codeine and meperidinehydrochloride were required for relief. The skin and sclerae were jaundiced. There was painful adenopathy in bothgroins. Laetrile 1 gm was injected intravenously. In seven minutes the blood pressure dropped 68 mm and the skinbecame cold and clammy. The patient appeared to be in incipient shock but responded promptly to an injection ofphenylephrine hydrochloride, after which his blood pressure recovered 66 mm. Next day in injection of Laetrile 1 gmwas repeated. His systolic blood pressure dropped 10 mm, but there was no shock reaction. Following the secondinjection the pain ceased and the use of narcotics was no longer needed. Nausea and vomiting were relieved, andjaundice was reduced. In a period of four days he received three injections of Laetrile 1 gm. During this time there wasno pain and narcotic drugs were discontinued. Bleeding from the bladder ceased. Nausea and vomiting were relieved,and jaundice was diminished. Before and after hemograms and urinalyses showed no change.Case 9.: M.T., age 65, female, married, housewife, weight 110 lb., height 66 in., blood pressure 160/90 mm. Diagnosisadenocarcinoma of the pancreas and omentum. Hemoglobin 11,5 gm/100 cc. The liver was palpable and painfulnodules extended to about 3 inches below the costal margin. During the last seven months she had suffered fromextreme pain and had lost 20 lb. Meperidine hydrochloride was required for relief. She was exceedingly weak,jaundiced, emaciated, and unable to stand without assistance. Laetrile 1 gm was injected intravenously. There were noadverse effects. A second injection was given four days later. Pain was partially relieved and the dosage of meperidinehydrochloride was reduced. The blood picture and urinalysis showed no change under Laetrile therapy.Case 10.: F.E., age 17, male, single, student, weight 150 lb., height 71 in., blood pressure 110/70. Diagnosis Hodgkin’sdisease, granuloma type, with metastasis to the thorax. During the last three months a growing mass in the leftsupraclavicular region had reached the size of a quarter sphere of an average orange. The patient complained of pain inboth axillae, weakness, nausea and anorexia. He had lost 26 lb and was jaundiced. Biopsy confirmed the diagnosis. Theaxillary lymph glands were enlarged, especially on the right side. The roentgengrams showed progressive nodalenlargement inside the torax. Laetrile 1 gm was injected intravenously. In five minutes the systolic blood pressuredropped 6 mm, but there were no apparent other effects. On examination two days later the mass in the neck was softerand smaller. By the fifth day it was reduced to about half the original size, and was softer and movable. The axillarylymph glands were barely palpable. He was free from pain and his appetite had returned.In a period of five months he received thirty-six injections of Laetrile, nineteen of 1 gm, and seventeen of 2 gm. Therewere no side effects. During the period of treatment there was no pain and no enlargement of the supraclavicular massoccurred. Appetite improved and the patient gained 24 lb. He returned to his studies. Comparison of before and afterhemograms showed distinct improvement in the red blood cell count and haemoglobin.173

Allegated:Clinical Trial of Chemotherapeutic treatment of advanced cancerswith Leatrile (L-Mandelonitrile-Beta-Diglucoside)Guidetti EttoreRossi BenedettoDeckers ChristianPresented at the 9 th International Cancer Congress in Tokyo, October 1966From 1954 to 1966 we gave 150 patients the above-mentioned therapy, chiefy at San Cottolengo Hospital, Turin; DosioHospital, Milan; and Louvain University Cancer Institute. All patients were in the terminal stage of the disease, themajority of them prey to cachezia, and all other therapies had failed.The following table summarizes the cases treated, classified according to the site of the tumor, and showing the numberof patients for each degree of reaction to therapy. We use the sign ++ to denote patients who reacted in an objectivelyfavourable manner, by which we mean diminution of volume of the tumor or at least all interruption of its evolution,improvement in the roentgenographic picture, and improvement in laboratory findings. The mark + and + indicatespatients who showed a more or less distinct subjective improvement, and the mark – those who reacted negatively to thetreatment.Cases corresponding to ++ represent about 20% of those treated.We again underline the fact that the majority of these cases were simultaneously subjected to an immunotype therapy,which might have some bearing on the number of positive results observed, grouped under the signs ++ and + totallingabout half the number of cases treated.Cancer SiteNo. cases++ + + -Toruli tactiles 26 5 6 6 9Breast 25 3 8 7 7Uterus 24 7 7 4 6Rectum 20 2 9 2 7Ovary (with infusion) 10 2 2 2 4Other types 30 9 7 2 12Totals 135 28 39 23 45We have separately considered neoplasms of the pleura with effusion (15 cases), where the product was used direct byinjection in the pleural cavity. In these cases we observed our best results, as generally we obtained reduction and thenon occasion complete disappearance of the effusion, associated with a distinct improvement in the patients’ condition.Conclusion:On the basis of our clinical trial, we are able to state that L-mandelonitrile-beta-diglucoside may be considered anextremely useful chemotherapeutic drug for palliative medical treatment of malign neoplasms, from the standpoint bothof its therapeutic effect and its very low toxicity.174

Amygadin metabolic liver aspects(FROM INTERNET [ unknown the Author) :Detoxification of cyanide can take place in all tissues of the body, but principally in the liver. Thedosage levels and toxicity of amygdalin (Laetrile) in laboratory animals and humans is wellestablished and documented.No evidence of acute or accumulative toxicity was observed in any animals giving doses in excessof 100 times the maximum intravenous dose usually given in humans.These findings coincide with that mentioned by Otto Jacobsen in 1887, Davidson in 1944 and Dr.Dean Burk (National Cancer Institute) in 1968: "Amygdalin is impressively nontoxic from thepharmacological point of view", and "non-hydrolyzed amygdalin is less toxic than glucose". Theoral toxicity of amygdalin was found to be 39 to 44 times greater than the intramuscular route, andmore toxic than intravenous route (parentenal route). Amygdalin is less tolerable by oraladministration because of the hydrolysis of amygdalin by the gastric juices. On the other hand,amygdalin, in dosages of 20-40/mg/kg orally (for a 200 lb human this would translate to 16 -500mg laetrile/B17 tablets, daily), used in humans, is 10 to 20 times less than the minimum toxicdosage in dogs. The biological half life of amygdalin is only 80 minutes. Over 80% of theamygdalin administered is excreted from the body in 4 hours. The usual metabolic approach toamygdalin (laetrile) therapy is to provide the patient with adequate nutritional support, withrelatively nontoxic high doses of vitamins and minerals, and other active natural substances.Amygdalin (laetrile) has been administered in dosages of up to 70 grams (70,000 miligrams-mg)per day in adult humans by combined oral and parentenal routes without adverse effects.Ever since the days of Louis Pasteur (1822-1895) and Paul Ehrlich (1854-1915), cancer victimshave hoped for the "wonder vaccine" or the "magic bullet". Amygdalin (laetrile) does not comeunder the heading of either of these dramatic therapies. There are a number of factors that enter intothe cancer treatment complex. The type of cancer involved is an important factor. Some types ofcancer tend to be more sensitive to treatment than other. Amygdalin (laetrile) is not equallyeffective in all types of cancers. Rubin (1977) found in their clinical investigations in Israel thatAmygdalin (laetrile) was most effective against Adeno-carcinoma and Hodgkin's disease, somewhatless effective in certain other of the Sarcomas and Melanomas, and relatively poor results wereachieved with the Leukaemia. Similar results have been obtained by other clinicians in the UnitedStates and elsewhere. The best results with Amygdalin (laetrile) therapy have been achieved withLung, Prostate, Breast, Lymphomas, Liver and Brain cancer. The chemical quality of theAmygdalin (Laetrile) also has a bearing on the clinical therapeutic results.Only the laevo isomer of Amydalin (Laetrile) has been found to be therapeutically active. A highquality Amygdalin is now produced in Mexico and some products are currently under investigationin the United States and Germany . It is therefore of the utmost importance that quality products beutilized. Failure to recognize this point can result in inadequate dosage levels and false negativetherapeutic results (Krible, 1912; Levi, et al, 1965; Rubin, 1978). Other factors relating directly tothe administration of Amygdalin (Laetrile) concern the dosage. In the past, most physicians havetended toward administering too low a dosage. Therefore the frequency of administration, the routeof administration, and the dosage are of the utmost importance if adequate blood levels are to bemaintained. In the past, most errors of administration have been made on the side of too little, ratherthan too much. However, it should be kept in mind that the most effective routes are by parenteralinjection (I.M or I.V.) and the physician should not attempt to achieve the necessary dosage levelsby the oral route. Rubin (1978) reports administering 70 gr. per day to each patient with no illeffects. Another aspect that will have a bearing on the recovery of a patient depends upon thedegree of tissue damage caused by excessive radiation and toxicity resulting from Chemo-Therapy.It is presently estimated in the United States, Mexico, and elsewhere, that about 90% or more of thepatients begin using Amygdalin (Laetrile) only after all other types of cancer therapies have failed.Most metabolic physicians are of the opinion that if the patient were to begin Metabolic Therapy175

earlier in the course of the disease, it would improve the patient's chances of Cancer Control. Theadequacy of liver functions is of the utmost importance in cancer therapy. The liver has varied,intricate and extremely complex metabolic functions. Among other things the liver is concernedwith fat, carbohydrate and protein metabolism.The liver has a propensity for storing vitamins, especially A, D and B 12, and Iron in the form offerritin. The liver forms a large proportion of the blood constituents: Fibrinogen, Prothrombin,Accelerator Globulin, Factor VII, and other coagulation factors. The liver is involved in vitamin Kmetabolism. The liver is concerned with the vascular storage and filtration of blood, with about1,000 ml of blood flowing from the portal vein through the liver sinusoids each minute, and anadditional 400 ml flows into the sinusoid from the hepatic artery. Thus when the liver or kidneys aredamaged due to a primary or metastatic malignancy, it may adversely affect the entire metabolismof the body.The studies conducted thus far on Amygdalin (Laetrile) indicate that there is no damage to the liveror kidney function. Much of the effort of metabolic therapy is dedicated toward sustaining adequateliver and kidney functions, and to attempt to minimize the detoxification load placed upon them. Itshould be emphasized that Amygdalin (Laetrile) therapy is most effective when used in conjunctionwith a comprehensive METABOLIC approach. Most physicians using this form of therapy provideadequate nutritional support with the use of proper vitamin and mineral supplements. The patient isplaced on a complete vegetarian diet with a reduction of proteins, fats, refined sugars, and processedfoods. All tobacco, alcohol, caffeinated drinks, and most toxic medications are eliminated. Thepatient is placed on a high intake of select fruit juices, fresh fruits and vegetables. A program ofDetoxification is required. A minimum of 9 gr of Amygdalin (Laetrile) per day is administered,largely by the parenteral route, but even higher levels may be given if indicated. Patients that refuseto follow the general Metabolic Program are discouraged from taking Amygdalin (Laetrile) .176

Amygdalin poisoning: medical aspects1) Effect: quick tissue anoxia due to intracellular respiratory failure and toxic lesion of respiratorycentres.2) Amygdalin plasmatic half-life: about 80 minutes.3) Clinical symptoms: asthenia, torpor, somnolence, headache, vertigo, coma, dyspnea, apnea,polypnea, heart rhythm disorders (bradycardia, atrial fibrillation). Vomit and diarrhea are possibleas well. High abdominal pain. Not associated with cyanotic coloration.Basic therapy1) Artificial breathing with 100% oxygen.2) Hypotension needs to be treated with sympathomimetic amines (if it is of cardiogenic origin) orwith liquid infusion (if it is of hypovolemic origin).3) Electrolytes and acid-base balance have to be checked (risk for lactic acidosis).Antidotal therapy1) Inhalation of gauze pads soaked with a vial of amile nitrate for 15-30 seconds, to be repeatedevery 2-3 minutes using another vial.2) Slow endovenous infusion (3-5 minutes) of 10 millilitres of 3% sodium nitrite solution.3) Endovenous infusion of 50 millilitres of 25% sodium thiosulfate.Clinical observation must be intense for at least 24 hours. Medical treatment should be correctedaccording to methaemoglobin monitoring (it should not be more than 40%).Therapeutic dosage of vitamin B17The various kinds of seeds or food contain adequate quantities of vitamin B17. But, unfortunately, itis not possible to calculate the bioavailability of these foods for absorption of vitamin B17 byintestinal walls, and this depends on many factors. Empirically, in adult patients weighing about 70kg, it can be lethal to administrate daily 15 (fifteen) bitter almond seeds, or 30 (thirty) peach bitterseeds, or 300 (three hundred) apricot bitter seeds.On the contrary, even a quantity as small as 2-3 bitter almond seeds is deadly for a child.Table 7.1 shows the quantity of vitamin B17 found in 100 grams of fruit.Table 7.2 shows the quantity of vitamin B17 found in 100 grams of seeds.Table 7.3 shows the quantity of vitamin B17 found in 100 grams of various types of leaves.Table 7.4 shows the quantity of vitamin B17 found in 100 grams of various types of tubers.177

Table 7.1Quantity of B 17 in 100 grams Fruit typeLess than100 mgBlackberry (Rubus fructicosus)about 500 mgWild blackberry (Rubus fructicosus)about 500 mgCherry core (Prunus avium)about 500 mgWild apple (Malus communis)about 500 mgSwedish blueberry100-300 mg Grapes (Vitis vinifera)100-500 mg Elderberry (Sambucus nigra)100-300 mg Gooseberry (Ribes grossularia) Barberry (Berberis vulgaris)100-300 mg European blueberry (Vaccinium myrtillus) or American blueberry (Gaylussacia baccata)100-300 mg Morus nigra (Black mulberry)100-300 mg Rubus ursinus loganobaccus, Arctostaphilos uva ursi (California blackberry)100-300 mg Raspberry (Rubus idaeus), Vaccinium vitis idaea (Cranberries).100-300 mg Quince (Cydonia oblonga)UnknownIndian Fig (Opuntia ficus indica)UnknownGraviola (Annona muricata)Table 7.2Quantity of B17 in 100 gramsSeed Typeabout 500 mgApple seeds (Malus communis)about 500 mgApricot seeds (Prunus armeniaca)100-300 mg Buckwheat seeds (Fagopyrum esculentum)about 500 mgCherry seeds (Prunus avium)100-300 mg Flax seeds (Linum usitatissimum)100-300 mg Millet seeds (Panicum miliaceum)about 500 mg Nectarine seeds (Prunus persica nectarina )about 500 mgPeach seeds (Prunus persica)about 500 mgPear seeds (Pyrus communis)about 500 mgPlum seeds (Prunus domestica)100-300 mg Pumpkin seeds (Cucurbita maxima)about 500 mgRape seeds (No OGM)UnknownIndian Fig seeds (Opuntia ficus indica)UnknownKiwi seeds (Actinidia sinensis)UnknownCedar seeds (Citrus medica)UnknownLemon seeds (Citrus limonum)UnknownGrapes seeds (Vitis vinifera)UnknownMelon seeds (Cucumis melo)UnknownWatermelon seeds (Citrullus vulgaris)UnknownCucumber seeds (Cucumis sativus)UnknownGrapefruit seeds (Citrus decumana, paradisi)UnknownBergamot seeds (Citrus aurantium bergamia)Table 7.3Quantity of B 17 in 100 gramsLeave typeLess than 100 mgBroccoli (Brassica oleracea botrytis aut italica)Less than 100 mg Spinach leaves (Spinacia oleracea )about 500 mgAlfalfa leaves (not buds) (Medicago sativa)about 500 mgEucalyptus leaves (Eucalyptus globulus)100-300 mg Watercress leaves (Nasturtium officinale)UnknownAloe leaves (Arborescens, ferox, vera, etc…)UnknownIndian Fig leaves (Opuntia ficus indica)Unknown Melaleuca leaves (Melaleuca alternifolia )178

Table 7.4Quantity of B 17 in 100 gramsTuber typeLess than100 mg White potatoes (Solanum tuberosus )about 500 mgManioca, Cassava (Manihot utilissima) (note: NO GMO)Unknown Red potatoes (Solanum tuberosus )Under examination: Heracleum sphondylium (Italian ginseng), Daucus gingidium, Arbutus unedo,Sanguisorba officinalis (Sorb-apple), Hedera helix (Ivy).Various sources report a very low biological half-life of about 80 minutes. This confirms that it ispossible to administrate a maximum dose of about 5-7 apricot bitter seeds every hour for adults.Some American doctors that have been working in Mexican clinics for the past 30 years claim thata safe dosage for an adult weighing 70 kg is about 5-7 bitter seeds every hour, about 100-250 seedsper day in total. Daily administration of 250-300 apricot seeds in an adult weighing 70 kg gives aquantity of vitamin B17 that is surely toxic. According to these doctors, it is important that seedsare taken on a full stomach, to avoid partial hydrolysis of Amygdalin by gastric juices. This wouldproduce Cyanide ions directly in the stomach. Moreover, in their opinion endovenousadministration of Amygdalin can be useful, because it is more tolerated as the maximum dosewithout reaching the above mentioned toxic quantities.Finally, it is important to start administrating Amygdalin, if orally, in low doses, not higher than 5bitter seeds per day, for the first week, and then 7-10 bitter seeds in the following weeks, atdifferent intervals.The bioavailability of apricot seeds is very high compared to other sources of vitamin B17.However, I take no responsibility for B17 therapies carried out without a doctor’s supervision. Iespecially advise against this therapy on patients who already underwent chemotherapy. Their livercannot properly detoxify blood from Cyanide ions and benzaldehyde. As far as this is concerned,doctor Moertel’s work, published on N.Engl.J.Med. in 1982 (Moertel CG: A clinical trial of amygdalin(laetrile) in the treatment of human cancer, N.Engl.J.Med., 306, pp.: 201-206 ( 1256 ), shows this therapy’scomplete failure (http://fiocco59.altervista.org/nacci/Moertel%201982.pdf )Note on the work of New Engl.J.Med., 1982 (Moertel CG: A clinical trial of amygdalin (laetrile) in the treatment ofhuman cancer, N.Engl.J.Med., 306, pp.: 201-206): this work was conduced by the dr. Moertel of the Mayo Clinic; Inthis work are:1) Chemically pure amygdalin was not used. Instead a mixture, which supposedly mimicked what was being usedin a Mexican Clinic.2) 70 per cent of these patients were stable during the first three weeks of the study, during which the patientsreceived intravenous amygdalin.3) Once the patients were switched to oral amygdalin alone, they did deteriorate fairly quickly.4) Supporters of amygdalin do not believe that this study was valid proof against amygdalin efficacy.From : England Journal of Medicine, 307, pp.119, 1982 (on the work of dr. Moertel CG: A clinical trial of amygdalin(laetrile) in the treatment of human cancer, N.Engl.J.Med., 306, pp.: 201-206 ;http://fiocco59.altervista.org/nacci/Moertel%201982.pdf)To the Editor: In the article on the Laetrile clinical trial, the investigators state, “No substantive benefit was observed interms of cure, improvement, or stabilization of cancer, improvement of symptoms related to cancer, or extension of lifespan”. In the accompanying editorial there appears the statement, “Even when combined with the “metabolic” therapy(vitamins and a “natural” diet) so enthusiastically touted by the anti-establishment cancer therapists, Laetrile producedno discernible benefit in a group of 178 patients with a variety of types of advanced cancer”. As one of the touters, Iwish to point out that these conclusions are not justified by the evidence. The reason for my contention is that there wasno control group with which the group of treated patients could be compared.The investigators say that the median survival time was 4,8 months (five months for patients with colorectal cancer, fivemonths for those with lung cancer, four months for those with breast cancer, and three months for those withmelanoma), and they claim , “These survival times appear to be consistent with the anticipated survivals in comparablepatients receiving inactive treatment or no treatment “. No survival curves for these comparable patients are presented,179

nor are there any references to pertinent reports. The editorial states that “The lack of concurrent controls was partiallyoffset by the fact that all patients were in the advanced stages of a disease known to be almost uniformly and rapidlyfatal. Any objective responses in tumor size or apparent prolongation of survival could be identified by comparison withhistorical controls. But there was not the slightest suggestion of any beneficial effect”.It is my opinion that there probably was a beneficial effect, including prolongation of survival. Other studies haveshown that the median survival time in patients with cancer “for which no standard treatment was known to be curativeor to extend life expectancy” was about 1,4 months; an example is the control group in the study by Creagan et al.(Failure of high-dose vitamin C therapy to benefit patients with advanced cancer: a controlled trial. New EnglandJournal Medicine, 1979, No. 301, pp: 687-690).The observed median of 4,5 months accordingly constitutes a substantial increase. In any case, it is improper toannounce a negative result without performing a careful statistical analysis of the treated group and a suitable controlgroup.The report by Moertel et al is marred by other errors and imperfections. For example, Figure 3 shows that 10 of the 178patients in the group survived to the end of the study, whereas in the text it is stated that 26 of the 178 survived; one ofthese numbers is wrong.One third of the patients had not received chemotherapy, but despite the well-known contention that vitamins and diethave greater value for these patients than for those who have received chemotherapy, no statistical analysis of theobservations on the two sub-groups is presented. Moreover, 14 of the 178 patients received much higher doses ofvitamins than the others did, but little information is given about these 14 patients, and no statistical analysis of theirresponses in comparison to those of the others is reported.LINUS PAULING Ph.D.Linus Pauling Institute of Science and MedicinePalo Alto, CA 94306To the Editor: Despite your belief that the National Cancer Institute (NCI) “clinical trial” of Laetrile “closes the books”on the use of amygdalin in cancer therapy, your readers should be well aware of many dissenting views and of ourwidespread suspicion that the trials were designed to make certain that Laetrile – or whatever the NCI was construing tobe Laetrile –failed.This organisation and the undersigned are parties to ongoing litigation against the NCI in regard to the conducting of thetrials.Officers of this organisation were the only Laetrile proponents who assisted at the early stages in developing the NCIdesign protocols for the study.We became involved in litigation only after it became clear to us that the NCI was going to test not pure amygdalin buta degraded or decomposed form of it (the putative “RS-epimer racemic mixture” said by Moertel et al. to be a copy ofmaterial provided by a major Mexican manufacturer).Let me stress that our side does not believe that even with appropriate material the lives of most of the patients withincurable or inoperable cancer could have been saved.It is our belief that the patients’ responses within the first three weeks of treatment (when most patients were on the 21-day injectable part of the program) indicate at least some fleeting anti-neoplastic action, even from the degradedproduct. Indeed, by any of the various semantic renderings of the results of the first three weeks of therapy, either amajority of patients were stable or a sizable minority (46 per cent) had no signs of progressive disease during this partof the program. Unless the English language has substantially changed during the past 24 months, I cannot interpretthese renderings as other than suggesting limited efficacy of the injectable material. Would it not have been wise tocontinue giving injections and to make a real effort at a real metabolic program in these incurable patients ?Our side also laments the lack of any Laetrile-using physician in the NCI program and the lack of available raw data onthe patients.We insist that the NCI “clinical trial” has asked far more questions than it has answered about Laetrile, but that by nostretch of the imagination can it be said to have “closed the books” on Laetrile.Michael CulbertCommittee for Freedom of Choise in Cancer Therapy, Inc.Los Altos, CA 94022180

Chapter 8:Retroviruses and CancerFROM: Jawetz E.:”Review of Medical Microbiology”, 1980 Lange Medical Publications, Los Altos, CaliforniaIn the past the viral origin of tumours was widely discussed.Nowadays, a number of viruses is known to induce tumours in men and animals.The production of tumour without viral replication was observed in both DNA and RNA viruses.Although the first known malignant disease of viral origin, i.e. the avian leukaemia, was discoveredat the beginning of the 20th century, it was only in the ’60s and ’70s that viral oncology began to bestudied extensively.Towards the end of the ’70s, the following conclusions could then be drawn:1) PROVED: the viral etiology of warts and of molluscum contagiosum in human beings(benign tumours).2) PROVED: clinical similarities, as well as anatomical, pathological and epidemiological ones,between human tumours and those of inferior animals, whose viral etiology was demonstrated.3) PROVED: the role played by some common viruses (Adenovirus, Herpes Virus) in theexperimental production of tumours in animals.4) PROVED: biophysical, biochemical and antigenic analogies between viruses of animaltumours and some human viruses.The intensification of studies allowed to discover the viral etiology of many common tumours ininferior animals. This was possible thanks to the technological progress achieved in tissue culturemethods, the use of newborn animals with known genetic constitution and the implementation ofmodern biophysical, biochemical and immunologic methods.The viruses which induce tumours can be divided into two main groups having different physical,chemical and biological properties: one group contains RNA as genetic material, the other DNA.The viral infection of a cell has been described as the penetration of a genetic system (virus) into thesphere of action (DNA) of another system (human or animal eukaryotic cell). The infection of a cellwith a cytocide virus causes its death, but the infection with a tumour virus brings to a simultaneouscoexistence of the virus and the cell, which profoundly changes the properties of the infected cell.This mechanism, known as cell transformation, has been studied in depth since the ’60s and ’70s.There is significant evidence showing that cancer involves one single cell at the beginning of itscourse. The modified cell has new, abnormal properties which are genetically transmitted to itsdaughter cells. The genetic modifications in tumour cells can lead to morphological, metabolic and181

antigenic alterations, leading to one of the following results: the modified cells spread to thesurrounding tissues, causing metastatic tumour in distant organs and tissues and the death of thehosting cell; alternatively, the hosting cell keeps its homeostasis through immunological controlmechanisms (humoral or cellular). Therefore, a tumour can be defined as a cell growth which ispermanently or temporarily beyond control; it can be generalised or metastatic, culminating in thedeath of the hosting cell (malignant tumour), or it can remain localised (benign tumour).RNA tumour VIRUSES (Oncornaviruses)Although DNA and RNA tumour viruses differ profoundly in their replication mechanisms, the factthat Oncornavirus genes – similarly to those of DNA tumour viruses – integrate in the hosting cell’schromosome DNA, may show a shared mechanism of Oncogenesis for the two viral agent groups.Oncornaviruses are all similar in structure, chemical composition, reaction to chemical and physicalagents and replication. They are divided in types A, B and C according to morphological, antigenicand enzymatic differences.They constitute a subfamily – known as Oncornaviridae – of the Retroviridae family, because allmembers contain reverse transcriptase (RNA-dependent DNA polymerase), which allows them totranscribe their viral RNA into the hosting cell’s DNA. Then, after the single-stranded DNAmolecules have been extracted from the RNA-DNA hybrid by another enzyme (RNAase H), theyare able to synthesize double-stranded DNA molecules. What is known about them strengthens thehypothesis that Oncornavirus RNA replicates in vivo in man through an intermediary DNA.The reverse transcriptase of Oncornaviruses was purified and proved to be a protein of the virus’sinner part, with a molecular weight of about 60,000-80,000 Daltons, separable from Oncornavirusgs antigens. The reverse transcriptase is not present only in the Oncornaviruses described below.Other types of RNA viruses, which cause latent infections in their hosting cell, have the abovementionedenzyme.This has been proved for antigenically correlated viruses (Visna Virus) which cause “slow”infections in sheep, a disease clinically similar to Bovine Spongiform Encephalopathy, and forviruses which form syncytia (foamy) and derive from Primates, cattle and felines.A well-known virus is HIV, thought to be correlated to AIDS (Acquired Immuno-deficiencySyndrome), whose causes are not completely clear; this disease was also assumed to have a viralorigin (the well-known SV40 DNA oncogenic virus).Many GMO plants (and also some breeding animals such as chickens and salmons) are modified byintroducing this kind of viruses, i.e. Retroviridae, containing the reverse transcriptase, in order tomodify the plant’s DNA (or to induce the production of the growth hormone or of other hormonesin breeding animals).Many of these viruses are classified within the subfamily of Oncornaviridae (family ofRetroviridae), because they share with them the reverse transcriptase – a feature of Retroviridae –and other biological and biophysical properties, such as that of causing tumours. The Visna Virus,for example, transforms murine cells in vitro; its RNA genome is composed of a 60-70S moleculewith the same properties as Oncornaviruses.182

It would therefore be advisable to analyse the Retroviridae used by GMO Multinationals to produceGMO plants in greater detail (or to induce the production of the growth hormone or other hormonesin breeding animals such as chickens and salmons).Reactions of Oncornaviruses to chemical and physical agentsBecause of the lipids contained in their envelope, RNA tumour viruses are sensible to ether. Theycan be deactivated by heating them at 56 degrees Celsius for 30 minutes, by treating them withweak acids (pH 4.5) and with formalin 1:4,000. Furthermore, they can be stored at temperatureslower than 70 degrees Celsius below zero.Antigenic properties of OncornavirusesOncornaviruses have two types of antigens:1) Type-specific or subgroup-specific antigens which are linked to the viral envelope and arefound in single strains or groups of strains among the Oncornaviruses of each species. Theyare codified by the env gene. They can be detected through serologic tests, such asneutralization, complement fixation, immunodiffusion and immuno-fluorescence withserums of animals affected by tumours which produce the virus or with immune serumsused against whole virions. The envelop antigens of AVIAN C viruses contain at least 2glycoprotein components with a molecular weight of 85,000 Daltons and 35,000 Daltons.There are no crossed reactions between the envelope antigens of avian Oncornaviruses andmammals Oncornaviruses, or between Oncornaviruses belonging to different species ofmammals. Moreover, no crossed reactions take place between C and B viruses in the murinesystem, or between C and D viruses in the primate system.2) Group-specific antigens (gs) which are associated to the inner polypeptides of the centralpart of the virion. They are produced by cutting the polyprotein codified by the gag gene. Theycan be detected through tests such as complement fixation, immunodiffusion andimmunofluorescence, radio-immunoassays using animal serums of heterologous speciesaffected by virus-induced tumours, immune serums prepared against virions broken with Tween80 ether or monospecific immune serums against single polypeptides. The main gs antigen(p30) is a basic polypeptide with a molecular weight of about 30,000 Daltons; it is commonamong the C viruses of a hosting species (birds, felines, hamsters, mice, primates, rats, vipers).Crossed reactions between the p30 antigens of avian Oncornaviruses and those of mammalianOncornaviruses were not observed. Furthermore, there are no crossed reactions between the p30antigens of C and B viruses in mice or between C and D viruses in primates.183

Oncornavirus replication and cell transformationA common feature of Oncornaviruses is that they are not cytocide for the cells in which theyreplicate. Like other viruses, Oncornaviruses live an eclipse phase after infecting a cell. Thelatter, once infected, produces new viruses, continues multiplying and may or may not becomemalignant. The infectious virus and viral particles are easily detected in most tumour cells orcells transformed in vitro. Viruses mature on the cell membrane and are continuously releasedby the cell through the cell membrane budding. Immediately after penetrating and infecting thecell, the viral RNA is transcribed into DNA: the RNA-DNA hybrid is then further transcribedinto a double-stranded DNA which becomes integrated into the hosting cell’s DNA during celldivision. The integration of the specific viral DNA (Provirus) works as a permanent mark forthe RNA transcription of the viral progeny and also as a hereditary transmissible gene for thetransformation.Oncornavirus – induced tumoursNormally these viruses can cause tumours only in their hosting organisms, rarely in other kindsof animals, including man. It is not known whether the relative “respect for other species” – acharacteristic common to the natural Retroviridae mentioned below (Complexes A, B, C, D, E)– was kept in the Retroviridae which were manipulated in order to produce GMO plants oranimal feed, or to modify the DNA of some animals which are eaten by human beings, such assalmons, chickens, etc. It is only known that this “respect for other species” is not applied in thecase of DNA tumour viruses.184

Complex A[Complex of avian leukaemia – avian sarcoma]LeukaemiasLeukaemias usually affect chickens. Viruses inducing leukaemias are widely spread among theseanimals. The two main viral leukaemias are lymphoid leukaemia (avian lymphomatosis virus),myelogenous leukaemia (avian myeloblastosis virus) and erythroid leukaemia (avianerythroblastosis virus). The infectious virus and its physical particles can be found in highconcentrations in tumour cells, in peripheral blood and in other organs of infected animals. Thiscannot be seen in the case of DNA tumour viruses. Myeloblasts or erythroblasts obtained frominfected birds and grown through tissue culture continue to release viruses which can induce thedisease in chickens through inoculation. Almost all chicken farms are infected by different types ofthese viruses, in particular by the lymphomatosis virus. The virus is transmitted horizontallythrough saliva and faeces, causing in adult animals an infection characterised by temporary viremiaand persistent antibodies. Only relatively few adult birds develop signs of the clinical disease. Thevertical transmission was observed in hens – but not in cocks – affected by viremia. This kind ofnon-genetic vertical transmission allows for the transmission of the Oncornavirus informationthrough the germinal line in the form of a DNA provirus. The vertical transmission determineschickens affected by congenital viremia, which are tolerant to the virus, have no antibodies and arepermanent spreaders of the virus itself. The incidence of leukaemia in animals congenitally infectedis much higher than in animals infected by physical contact.SarcomasThe Rous sarcoma virus has been subjected to numerous experimental mutations since it wasisolated for the first time in 1911.Nowadays, the sarcoma is probably different from the natural one. These avian viruses differ fortheir oncogenesis, antigenic structure and host range. However, they cause sarcomas in birds ofall ages and in laboratory chicken embryos even though – unlike avian lymphomatosis viruses –they are not transmitted naturally. Furthermore, they induce tumours in ducks, turkeys, pigeonsand other birds. Schmidt-Ruppin subgroup viruses can infect mammal cells, thus inducingtumours – as already demonstrated when inoculated into newborn rats, Syrian and Chinesehamsters, rabbits, mice, guinea pigs and monkeys. These avian tumours usually still contain theinfectious virus, whereas those affecting mammals strangely do not.Note 1: These types of Retroviruses produce C particles. Particles similar to C-type Oncornaviruses were foundunder the electronic microscope in the cells or plasma of patients with solid tumours in man, such as Hodgkin’s andnon-Hodgkin’s lymphoma, and sarcomas.Note 2: Nowadays bibliographical research is being conducted to find out whether D-subgroup avian viruses wereused to create GMO plants. However, it is known that these types of Retroviruses – which induce leukaemias inchickens – were used as vectors to introduce human genes into their DNA in order to increase their production.Moreover, these Retroviruses were also used as vectors to implant the growth hormone gene in some species offarmed fishes (Salmons) with a view to making them grow faster.185

Complex B[Complex of murine leukaemia- murine sarcoma]LeukaemiasNumerous murine leukaemia viruses inducing different types of tumours were isolated. Forexample, Graffi virus causes myelogenous leukaemias in some rat strains and lymphatic leukaemiain others with a high percentage of cases.Gross virus is responsible for most leukaemic diseases: it was demonstrated that mostleukaemia viruses present murine pathogens in rats and that Moloney virus acts as a pathogenicagent also in hamsters.Newborn animals are the most susceptible to leukaemia viruses but the disease can also attackyoung and adult animals. Genetic factors play an important role in determining rat susceptibilityto viruses, the nature of the disease and virus transmission. A high number of infectious virusesand viral particles are present in infected animal blood and tumour tissues. Murine leukaemiaviruses are spread in nature and Gross virus is the prototype of these agents causing naturalleukaemias.SarcomasNumerous strains of these viruses were isolated. They induce sarcomas in hamsters, rats andnewborn mice. The transmission of some strains in rat cells allowed the RNA of the menome ofthe virus to obtain rat nucleic acid sequences.Note 1: These types of Retroviruses produce C particles. Particles similar to C-type Oncornaviruses were foundunder the electronic microscope in the cells or plasma of patients with solid tumours in man, such as Hodgkin’s andnon-Hodgkin’s lymphoma, and sarcomas.186

Complex C[Complex of the murine mammary tumour (carcinoma)]The oncogenesis of various viral strains belonging to this type is quite complex, as it derives fromthe interaction among viruses, the genetic constitution of the hosting cell and hormonal factors.The most virulent viral strain known (MuMTV) causes mammary adenocarcinomas in female mice,with large quantities of infectious virus and B particles within the tumour, the milk and the blood ofthe mouse. In these animals, the virus is transmitted from the mother to the offspring through themilk. The virus induces adeno-carcinomas in the mammary gland only, and only in mice ofsusceptible lines. The animals which do not develop any tumour remain infected at a subclinicallevel, and transmit the virus to their offspring.Studies conducted on a number of strains of mice in the ’70s showed that this highly virulent virus(MuMTV) was ubiquitous even in virus-positive mouse strains, but with a low incidence ofmammary cancer. In some mouse strains, the MuMTV virus was rarely expressed completely.Hybridization studies proved that the tissues of mouse strains with a low (e.g., BALB/c) or highfrequency (e.g., C3H) of mammary tumour contained DNA sequences of MuMTV and variablequantities of viral RNA. All mice presented endogenous sequences of the highly virulent MuMTVvirus in their DNA. However, the properties and functions of the “endogenous” MuMTV virus – asdistinct from the “exogenous” MuMTV virus, which is transmitted through milk – were notclarified.Again in the ’70s, some viral strains (GR) were also described which are transmitted verticallythrough the eyes or semen, apparently in the form of an integrated DNA provirus (genetic verticaltransmission).NOTE 1: These types of Retroviruses produce B particles. Particles similar to B-type Oncornaviruses were found inhuman mammary tumours and in the milk of both Parsi women (an Indian population with a very high incidence ofmammary cancer) and American women with a family anamnesis of mammary cancer. These particles contain RNA ofsignificant molecular weight (70S) and the enzymatic activities of reverse transcriptase, which are all characteristics ofRetroviruses. The serums of rabbits rendered immune against purified MTV precipitate a soluble antigen which can befound in the serums of women with mammary cancer. Furthermore, it was observed that the DNA synthesized in vitrofrom the VTM enzyme (by using the RNA of the VTM as a model) hybridizes with the polysomal RNA obtained frommammary adeno-carcinomas of the human species. Such hybridization could not be observed with the RNA derivingfrom other malignant diseases or normal human tissues. It was also indicated that the RNA contained in the extracts ofhuman mammary adeno-carcinomas is a 70S component carried within a particle with the same typical density ofOncornaviruses together with the RNA-directed DNA polymerase. The DNA synthesized in vitro from the combinationof 70S human RNA and enzyme specifically hybridizes with the RNA of the VTM. By adopting the same techniques,the research group found RNA complementary to the RNA of the murine leukaemia retrovirus (but not to that of theVTM) in other malignant tumours of the human species which are not related to mammary cancer. It could be observedthat the DNA obtained in vitro from the murine leukaemia retrovirus with reverse transcriptase hybridizes with theRNA obtained in the cells of various leukaemias, lymphomas (including Burkitt lymphoma) and sarcomas. It was shownthat the RNA contained in the cells of a number of human leukaemias is a 70S RNA combined with reversetranscriptase. It was finally noted that the DNA synthesized from this complex specifically hybridizes with the RNA ofthe murine leukaemia retrovirus, but not with the RNA of the VTM or of the virus of avian myeloblastosis.Note 2: Mammary carcinomas in the human species. It is not known whether these viruses can also infect milk cowsand consequently be transmitted to the human species. All these considerations are nonetheless of extreme concern inthe light of the present use of GMO animal feed, which is created in the laboratory with a frequent application ofRetroviruses and has been supplied to milk cows for approximately 10 years now. In the long run, there is a risk thatspontaneous transgenic modifications may occur, with consequent possible “epidemics” of mammary tumours in thehuman species.187

Complex D[Complex of feline leukaemia- feline sarcoma]The viruses of feline leukaemia and feline sarcoma were isolated from domestic cats suffering fromleukaemia and fibrosarcoma.LeukaemiaThe virus of leukaemia is an infectious agent commonly found in stray cat populations. Mostinfections are light and transitory, and only a minor percentage of cats develops leukaemias orlymphomas in their old age. 70% of cats with leukaemia release infectious viruses which are easilytransmitted to the animals of the same group. Newborn kitties are most sensible to the developmentof persistent viremia and the occurrence of tumours.SarcomaThe sarcoma virus is also frequently found. It can affect other species too, including dogs, rabbits,and apes.Note 1: These types of Retroviruses produce C particles. Particles similar to C-type Oncornaviruses were found underthe electronic microscope in the cells or plasma of patients with solid tumours in man, such as Hodgkin’s and non-Hodgkin’s lymphoma, and sarcomas.Human infection: It is not known whether these viruses can also infect the human species, but it hasbeen in any case proved that the virus of natural (i.e. non-GMO) feline sarcoma also affectsprimates. All these considerations are nonetheless of extreme concern in the light of the present useof GMO food for domestic cats and dogs, which is created in the laboratory with a frequentapplication of similar Retroviruses and has been sold as cat and dog food also in Europe forapproximately 10 years now. In the long run, there is a risk that “epidemics” of leukaemias andsarcomas may occur, first in domestic dogs and stray and/or domestic cats, and then in humanbeings because of the presence of such animals in homes, given the evidence that the virus ofnatural (i.e. non-GMO) feline sarcoma also affects primates.188

Complex E[Primate Oncornavirus]The woolly monkey sarcoma virus (SSV-1) induces sarcomas in newborn hapaline monkeys;the gibbon ape leukaemia virus (GALV) causes leukaemia in this species.These types of Retroviruses produce C particles. Particles similar to C-type Oncornaviruses werefound under the electronic microscope in the cells or plasma of patients with solid tumours in man,such as Hodgkin’s and non-Hodgkin’s lymphoma, and sarcomas.It is not known whether similar Retroviruses were used to produce GMO plants or breeding animalfeed.Other Retro-virusesVisna VirusThis is a virus causing demyelination of the Central Nervous System, with a clinical picturecompatible with Bovine Spongiform Encephalopathy. The incubation period ranges from a fewmonths to several years. It affects the sheep of Iceland.Considering its numerous similarities with RNA tumour viruses, this virus was included in thefamily of Retroviridae.Similarities include: assembly and maturation of the virion through budding, the virion’s diameter(70-100 nm), the presence of RNA-dependent DNA polymerase (reverse transcriptase), of 40S and70S RNA and of a similar polypeptide set. Furthermore, the virus contains projections and prickleson the external membrane, and the negative particles resemble those of the Rous sarcoma virus.Thread-like inner structures were also noted (C particles), similar to those described above foravian, murine and feline Retroviruses.HIVThis virus is suspected to be the agent causing AIDS, but the scientific debate is still open on theissue. Another AIDS-causing agent has recently been suggested: SV40 (DNA tumour virus).Note : Plants against AIDS : http://fiocco59.altervista.org/nacci/anti-AIDS%20plants.pdfB-EpatiteSEE medical Lecterature (cancer of liver)189

Chap. 8.2.:Dangers Inherent in the Process ItselfTHE USE OF CAULIFLOWER MOSAIC VIRUS35S Promoter (CaMV) in Calgene's Flavr Savr Tomato Creates HazardJoseph E. Cummins Associate Professor (Genetics) Dept. of Plant SciencesUniversity of Western Ontario London, Ontario N6A 5B7Telephone: (519) 679-2111 Ext. 6478Answering Machine: (519) 681-5477FAX: (519) 661-3935June 3, 1994"Feel free to reprint this article in unalterated form"The majority of crop plant constructions for herbicide or disease resistance employ a Promoter fromcauliflower mosaic virus (CaMV). Regardless of the gene transferred, all transfers require apromoter, which is like a motor driving production of the genes' message. Without a promoter, thegene is inactive, but replicated. CaMV is used because it is a powerful motor which drivesreplication of the retrovirus and is active in both angiosperms and gymnosperms. The CaMVpararetrovirus replication cycle involves production vegetative virus containing RNA which isreverse transcribed to make DNA similar to HIV, Human Leukemia Virus and Human hepatitis B.(Bonneville et al. RNA Genetics Vol.11, "Retroviruses, Viroids and RNA Recombination" pp. 23-42, 1988). CaMV is closely related to hepatitis B and is closely related to HIV (Doolittle et al.Quart.Rev.Biol. 64,1-30, 1989; Xiong and Eickbush, Origin and evolution of retroelements based upon theirriverse transcriptase sequences EMBO Journal 9, 3353, 1990). The CaMV promoter is preferred aboveother potential promoters because it is a more powerful promoter than others and is not greatlyinfluenced by environmental conditions or tissue types. CaMV has two Promoters 19S and 35S. Ofthese two the 35S promoter is most frequently used in biotechnology because it is most powerful.The 35S promoter is a DNA (or RNA) sequence about 400 base pairs in length. The use of theCaMV promoter in plants is analogous to the use of retrovirus LTR promoters in retrovirus vectorsused in human gene therapy. The majority of human gene therapy trials employ LTR promoters toprovide motors to activate genes.Antisense genes are genes constructed to have a complementary sequence to a target gene, thusproducing a product that combines with a gene message to inactivate it. Antisense is analogous toan antibody which combines with an antigen like a key fitting a lock. Antisense is being used totreat human cancer and HIV infection. Antisense is used to prevent spoilage in tomatos, either bytargeting an enzyme degrading cell walls (polygalacturonase), or production of ethylene a hormonepromoting ripening (P. Oeller et al. Genetic Engineering 49, 1989; R. Fray and D. Grierson, TrendsGenetics 9, 438, 1993). Most frequently antisense targets production of a chemical metaboliteproducing ethylene. The antisense gene also influenced polyamines spermine and spermidineproduction through S-adenosylmethionine. The implication is that the plant antisense gene productshould be tested in animals to ensure that critical functions including gene replication, spermactivity and gene imprinting are not disrupted.190

The perceived hazards of CaMV in crop plants include the consequences of recombination andpseudo recombination. Recombination is the exchanges of parts of genes or blocks of genesbetween chromosomes. Pseudorecombination is a situation in which gene components of one virusare exchanged with the protein coats of another. Frequently viruses may incorporate cellular genesby recombination or pseudorecombination, it has been noted that such recombinants have selectiveadvantages (Lai, Micro. Rev. 56, 61, 1992).It has been shown that the CaMV genes incorporated into the plant (canola) chromosome recombinewith infecting virus to produce more virulent new virus diseases. The designers of the experimentquestioned the safety of transgenic plants containing viral genes (S. Gal et al., Virology 187: 525,1992). Recombination between CaMV viruses involves the promoter (Vaden and Melcher,Virology 177: 717, 1992) and may take place either between DNA and DNA or RNA and RNA andfrequently creates more severe Infections than either parent (Mol. Plant-Microbe Interactions 5, 48,1992). Recently related experiments suggest altered plants may breed deadlier diseases (A. Greenand R. Allison, Sciences 263: 1423, 1994). DNA copies of RNA Viruses are frequently propagatedusing the CaMV 35S promoter to drive RNA virus production (J.Boyer and A. Haenni, Virology198: 415, 1994 and J.Desuns and G.Lomonossoff, J. Gen. Vir. 74: 889, 1993). In conclusion CaMVpromoters recombine with the infecting viruses to produce virulent new diseases. CaMV virusesand promoter may incorporate genes from the host creating virulent new diseases.CaMV can recombine with insect viruses and propagated in insect cells (D. Zuidema et al. J. Gen.Vir. 71: 312, 1990). Thus it is likely that as large numbers of humans consume CaMV modifiedtomatos recombination between CaMV and hepatitis B viruses will take place creating a superviruspropagated in plants, insects and humans.Plant biotechnology has grown out of recombinant DNA research that began in the early 1970's.The special nature of recombination has been debated since that time. In recent years, governmentregulators on the American and European continents, under pressure from well-funded lobbyrepresenting the biotechnology industry, have chosen to ignore the special nature of recombination.They have chosen instead to base regulations on existing frameworks for toxic chemicals andpathogenic organisms. Ignoring the special nature of recombination is likely to have costly, if notterminal, environmental consequences. A worst-case example includes the complete cloning ofHuman Immunodeficiency Virus (HIV) on an E. coli plasmid. When the plasmid is used totransform animal cells, intact HIV viruses are released from the cells. A careless (but legal) releaseof HIV bacteria to the environment would allow the plasmid to transfer to Salmonella as well as E.coli. Thus, numerous mammals and birds could contain HIV bacteria which could transform theanimals, which would in turn produce HIV particles unable to target the animals T-cell receptorsbut easily transmitted to humans. When all the animals are HIV carriers, human survival would bemarginal. The special concerns of recombination in plant biotechnology include the viruses andbacteria used in crop plant construction and gene flow between related crop plants and weeds in thefield.Currently most experts agree that virus diseases such as influenza gain strength for epidemics byalternating between animal hosts (pigs and ducks) and man. Epidemics begin when rarecombinations appear in large closely associated populations such as in Asia. CaMV can propagatein plant and insect hosts following recombination. It may not be outlandish to predict that CaMV191

may recombine with related Hepatitis B or for that matter HIV to create a most powerful disease.The salient feature being large number of people or animals consuming large numbers of virusgenes incorporated into crop plants making up a major part of human and animal diet.The use of CaMV promoter is seldom an issue in reviews of safety of gene tinkered crops. Fewpeople have raised the important issue and more often than not their concerns are ignored bygovernment officials "protecting" public safety. This omission may be a fatal one because it haspotentially the most damaging impact, and the one perceived at the beginning of gene splicing.ConclusionAs Bill Mollison said; "the time for evidence is over, there is only time for action." Or in the moreeloquent words of Kant, "It is often necessary to take a decision on the basis of knowledge sufficientfor action, but insufficient to satisfy the intellect." In this case I think we are faced with a situationdemanding the latter.If we campaign wholeheartedly for a ban we are on solid scientific ground. We can appeal directlyto people to help, and show them why it is important. The campaign for labelling is making theissue of a life-threatening technology appear to be merely an issue of civil rights. This is playingright into the hands of the biotech corporations. I would like to see a debate about how to stop them,not about how to allow them to carry on. No one has the right to choose something that threatensthe lives of others. These new organisms must be stopped. The democratic process is beingsubverted by powerful corporations who are taking direct action with no mandate. How should wereact?192

Chap. 8.3.: Scentific Article in WEBPairs of mutant cauliflower mosaic virus (CaMV) DNAs readily recombinein plants: three cloned chimeras resulted from multiple recombinationevents….. It suggesting that recombination of double-stranded DNAs mayalso generate CaMV DNA recombinantsRay Vaden: Recombination sites in Cauliflower Mosaic Virus DNAs; implications for Mechanisms of recombination,Virology, No.177, pp: 717-726, 1990 http://www.dirittolibertadicura.org/images/OGM/ray%20vaden%20.pdf…In several cases transgenic plants may contain mixtures of nucleic acidsfrom different viruses provided by an external source, e.g. an insect vector….. both DNA and RNA recombination events may have been involved inthe production of functional virus….Gal S.: Agroinfection of transgenic plants leads to viable Cauliflower Mosaic Virus by intermolecular recombination,Virology, No.187, pp.: 525-533, 1992 http://www.dirittolibertadicura.org/images/OGM/gal.pdf….Analysis of viral RNA confirmed that RNA recombination had unitedthe transgenic messenger RNA and the challenging virus through aberranthomologous recombination…..Greene A..: Recombination between viral RNA and transgenic plant transcripts, Science, Vol. 263, 11 march 1994http://www.dirittolibertadicura.org/images/OGM/greene.pdf...Different strategies employed to obtain infectious clones fromnonretroviral RNA viruses and the different possible parameters affectinginfectivity of such clones, keeping in mind, however, that the success orfailure of the construction of these clones is often empirical and that veryfew systematic studies have been performed on the different parametersinvolved….Boyer J.C.: Infectious transcripts and cDNA clones of RNA Viruses, Virology, No. 198, pp.: 415-426, 1994http://www.dirittolibertadicura.org/images/OGM/boyer.pdf193

…When a segment of a specific viral genome is expressed in a transgenicplant….several independent investigations have demonstrated thattransgenic transcripts are available to replicating viruses….Allison R.F.: Recombination in plants expressing viral transgenes, Seminars in Virology, Vol. 7, pp.: 417-422, 1996http://www.dirittolibertadicura.org/images/OGM/allison.pdf…..We demonstrate that recombinant viruses can be isolated fromtransgenic plants….an analysis of 24 infected plants showed that arecombination event occurred in every plant, demonstrating that understrong selection conditions, the recovery of CaMV recombinants fromtransgenic plants can be very high….Wintermantel W.M.: Isolation of recombinant viruses between Culiflower Mosaic Virus and a viral gene in transgenicplants under conditions of moderate selection pressure, Virology, No. 223, pp.: 156-164, 1996http://www.dirittolibertadicura.org/images/OGM/wintermantel.pdf….Cauliflower mosaic virus 35S promoter…. its activity in human cellsmay have impact on the risk assessment for the environmental release ofgenetically modified plants… the results showed very low but measurableactivity of 35S promoter in human 293T – cells (0,01% of that revealedwhen using pCMV…… In potato protoplasts pCMV displayednearly 1% activity seen with p35S…Vlasak J.: Comparison of hCMV immediate early and CaMV 35S promoters in both plant and human cells, Journal ofBiotechnology No. 103, pp.: 197-202, 2003. http://www.dirittolibertadicura.org/images/OGM/vlasak.pdf194

OTHER:Latham J.: GM Gene Flow (B): Horizontal gene transfer of viral inserts from GM plants to viruses,Technical paper, February 2004 http://www.dirittolibertadicura.org/images/OGM/latham.pdfZuidemahttp://www.mednat.org/alimentazione/zuidema.pdfDessenshttp://www.mednat.org/alimentazione/dessens.pdfHammond J.: Epidemiological risks from mixed virus infections and transgenicplants expressing viral genes; Maryland USA; Adv Virus Res., 1999, 54, pp. 189-314.Xiong Yue Eickbush T.: Origin and evolution of retroelements based upon their riversetranscriptase sequences, EMBO Journal, vol. 9, No.10, pp.: 3353-3362, 1990http://www.mednat.org/alimentazione/EMBO%20JOURNAL%201990.pdf195

Chapter 9:Immune TherapyImmune therapy is the immune response against tumors, carried out by means of gamma delta TLymphocytes, cytotoxic T Lymphocytes, killer lymphocytes and Natural Killers, real guide systemsof a complete immune response of the patient against the tumor itself (start of the ImmuneCascade).There are different scientific studies on this subject:JAMA, 278: 1972-1981, 1997; Crit. Rev. Oncol.-Hematol, 22, pp.: 213-228, 1996; Semin. immunol., 8, pp. 295-302,1996; Sem. Oncol., 23, pp.: 101-107, 1996; Springer Semin. Immunopath. 18, pp.: 185-198, 1996; Cancer Met Rev., 15,pp:329-349, 1996; Ann. Rev. Immunol., 12, pp.: 337-365, 1994; Adv Immunol. 35, pp.: 89-122, 1984.Brain cancer : J. Neurosurgery 77, pp 757-762, 1992; Cellular Immunology, 178, pp: 101-107, 1997; J. Neuro-Oncology, 32, pp.: 29-38, 1997.Breast cancer : Cancer Gene Therapy, 4, pp.: 157-166, 1997; Surgery, 122, pp.: 228-234, 1997. Per tumori delColon: Blood 89, pp: 2529-2536, 1997;Leukaemia: Progress Cancer Research and Therapeutics, 22, pp: 127-133, 1982;Liver cancer: J. Immunology, 161, pp.: 5133-5137, 1998;Lung cancer: Blood 89, pp.: 2529-2536, 1997; J. Immunology 147, pp: 729-737, 1991; J. Immunology 143, pp.:740-748, 1989.Melanoma: Cancer Immunology, Immunotherapy, 42, pp.: 237-245, 1996; J. Immunotherapy, 13, pp.: 153-165, 1993.The Immune Cascade, induced to fight the tumor, is carried out by means of the use of phytotherapy (plant therapy), because it is considered safer compared to the complex methodology ofextracting Lymphocytes from the tumor, cultivating them in a sterile environment, and thenreinjecting them, intravenously, into the patient, as Rosemburg and other authors [see: PizzaGiancarlo: Immunotherapy of metastatic kidney cancer, Int. J. Cancer, 94, pp.109-120, 2001]).There have been many studies carried out on the search for natural substances which have an antineoplasticimmune-modulating action9, 11, 32, 44, 50, 53, 61, 67, 82, 105, 126, 132, 144, 145, 146, 180, 196, 198, 225, 236,(278, 279, 306, 310, 319, 331, 346, 351, 359, 368, 372-381, 387, 388, 394, 395, 406, 412, 418, 419, 430, 444, 456, 462, 472, 474, 500, 516, 517, 520,577 ).The majority of tumoral antigen markers, which were well thought of during the 1980s as specifictumoral antigens, are in fact differentiating antigens, that is, antigens which appear along thematuring lines of the cell as embryonal antigens.Not all tumoral cells express the same antigens at the same time and irrespective of the cellularcycle, it is thought that these antigens can cause a weak cytotoxic reaction mediated by thelymphocytes, perhaps because of carbohydrate structures screening the protein structures, which arethe real determining antigens;( 507 ).196

The activation of the T lymphocyte suppressors is caused by the weak immune response to thetumor: in the case, that is, of a spontaneously arising tumor, the presence at the beginning of a lownumber of cells favors rather than inhibits its growth by means of a mechanism mediated by the Tsuppressors.It is still much debated whether the regional lymph nodes form an immune or even only a mechanicbarrier to the spread of the metastasis.The lymph nodes next to the tumor often do not contain tumoral cells but they show a hyper-plasticreaction which suggests the existence of a reaction of the host against the tumor or its derivatives.The theory has also been proposed that the lymph nodes have a limited capacity to eliminate neoplasticcells.It is thought that the limit of this action is exactly connected to the number of malignant cells whichreach the lymph node, a value which has to be less than 500-1.000 cells to avoid the onset of ametastasis.The destruction of metastasizing cells is started, above all, by the histiocyte macrophages of thebreasts with a hyper-plastic reaction of these, which is then followed by an active infiltration of thetumoral micro-metastasis caused by cytotoxic T lymphocytes and Natural-Killers (NK) ( 507 ).These are thought to have a spontaneous reactivity against both primary and metastasis cancerouscells, without any manifestation of histocompatability or of specific types for the function of theinteraction of the cells.Rats with a low level of NK, if treated with Beta-estradiol increase their NK quite significantly,with significant reductions in the number of metastases( 507 ).Even the neutrophils of peripheral human blood have been shown, in vitro, capable of inhibiting thegrowth of cancerous cells of either human or murine origin, with a strength ratio of 40 to1 betweeneffector cells and neo-plastic cells; and always if the latter are covered by antibodies ( 507 ).Macrophage-Monocytes show cytotoxity of a phagocytic type on neo-plastic cells even in theabsence of precise stimulation; their cytotoxity is thought to occur by means of a bond, favored bythe receptor for the FC portion of the antibody and of the complement, to the antigen target coveredby antibodies with a strength ratio of 1 to 1, after which the cells may be destroyed ( 507 ).Recently, there has also been notable interest regarding T Lymphocytes, which might be activatedby particular substances, such as lecithin, which is contained in Aloe for example ( 499 ).The following plants might also be useful, because they are forerunners of Prostaglandin andtherefore they assist in the Immune Cascade: oil of Borrago officinalis (Borragine [note; eliminatethe fine down which covers it]); oil of Oenothera biensis (Enotera); the leaves of Nelumbiumspeciosum (Kamala), which contain two essential unsaturated fatty acids (vitamin F): gammalinolenicacid and linolenic acid: the two acids cis-linolenic and gamma linolenic introduce anumber of essential fatty acids into the human biochemical complex; then, the delta 6 desaturatedblock is overcome through gamma-linolenic acid (GLA) encouraging the production ofProtaglandin and so setting off the first phase of the Immune Cascade.The immune response to the tumor is fully demonstrated by the use of other phytotherapeuticsubstances( 621,773,793,794 ) such as extract of Viscum album (Mistletoe) and above all by a variety ofcombinations of European, Asian, American, Australian and African herbs, or by using themindividually: Echinacea purpurea, Astragalus membranaceus, Panax ginseng, Rhodiola rosea,Morinda citrifolia, Campanula latifolia, Tribulus terrestris, Uncaria tomentosa, Sida cordifolia,Arctium lappa, Rumex acetosa, Rumex crispus, Bacopa monnieri, Rheum palmatum or officinale,Trifolium pratensae, Calendula officinalis, Achillea filipendulina, Urtica dioica, Acalypha indica,Taraxacum officinale, Malva silvestris or vulgaris, Epilobium angustifolium or parviflorum,Artemisia abrotanum or dracunculus, Salvia officinalis or lavandulifolia, Equisetum arvenseCrocus sativus, Polygala senega, Thymus vulgaris, Citrullus colocynthis, Primula veris or197

officinalis, Ailanthus glandulosa, Thymus serpillum, Sysymbrium officinale, Aquilaria agallocha,Eclipta alba, Larrea mexicana, Viola tricolor, Drosera rotundifolia or anglica, or intermedia,Argemone mexicana, Sambucus nigra, Smilax sarsaparilla or utilitis, Myrica cerifera, Rosmarinusofficinalis, Cinnamomum zeylanicum, Adiantum capillus veneris, Luffa operculata, Tephorosiapurpurea, Nepeta cataria, Momordica charantia, Trigonella foenum graecum, Verbascum thapsusor densiflorum, Serenoa repens, Sempervivum montanum, Ajuga reptans or piramidalis, Gnafaliumsupinum, Citrus aurantium bergamia, Draba aizoides, Hieracium pilosella, Cicerbita alpina,Hypericum richeri, Angelica archangelica, Leucanthemopsis alpina, Primula hirsuta, Saxifragaoppositifolia, Cerastium alpinum, Cirsium spinosissimum, Pedicularis rostrato-capitata, Potentillagrandiflora, Annona squamosa, Gentiana germanica, Saxifraga aizoides, Antennaria dioica,Argyreia speciosa (o Lettsomia nervosa), Moringa pterygosperma, Antyllis alpestris, Hypoxishemerocallidea, Eupatorium perfoliatum or purpureum, Euspongia officinalis, Glycyrrhiza glabra,Lycopodium clavatum, Galphimia glauca, Albizzia lebbek, Sticta pulmonaria or Lobariapulmonaria, Holarrhena antidysenterica, Sutherlandia frutescens, Chimaphila umbellata, Myristicafragrans or sebifera, Grindelia camporum or squarrosa, Althaea officinalis, Guajacum officinalis,Boswellia serrata, Myroxylon balsamum, Erithrea antaurium, Pulmonaria officinalis orangustifolia, Peucedanum ostruthium, Bambusa arundinacea, Ocimum basilicum, sanctum ortenuiflorum, Ceanothus americanus, Cassia angustifolia, Centaurea erythreum, Rhamnus sagradaor purshiana, Aralia racemosa, Rhamnus frangula (or Frangula alnus), Curcuma longa, Terminaliachebula, Lepidium meyenii, Mahonia aquifolium, Stachys arvensis, Abuta grandifolia, Polygonumaviculare, Ailantus glandulosa, Geranium robertianum, Marasdenia cundurango, Melissa monardaor officinalis, Alchimilla alpina or vulgaris, Asparagus racemosus, Apium graveolens, Lamiumalbum, Pimpinella major, Lysimachia nummularia, Marrubium vulgare, Acorus calamus, Galiumaparine, Lapsana communis, Glechoma hederaceum, Myrtus communis, Cinchona calisaya orsuccirubra, Meum mutellina, Picramnia antidesma, Azadirachta indica, Achyrocline satureoides,Polypodium lepidopteris, Anacardium occidentale, Bidens pilosa, Bixa orellana, Carapaguianensis, Scutellaria baicalensis o latiflora, Nelumbo nucifera, Boerhaavia diffusa, Calendulasilvestris, Cassia occidentalis, Houttuynia cordata, Cayaponia tayuya, Cissampelos pareira,Asparagus cochinensis, Copaifera officinalis, Cynara scolymus, Erythrina mulungu, Erythroxylumcatuaba, Ilex paraguariensis, Inesinae calea, Lepidium meyenii, Maytenus krukovit, Maytenusillicifolia, Myroxylon balsamum or pereirae, Pfaffia paniculata, Phyllantus niruri, Physalisangulata or Muehenbeckia volcanica, Psidium guajava, Schinus molle, Solanum paniculatum, andanother….198

Chapter 9.a : Immune stimulation : the experience of S.A.RosenbergIn 1986, Rosenberg demonstrated that an immune mediated cell response, aimed at neo-plasticclones, was possible ( 375 ), even if the exact mechanism by which the Tumor Infiltrated Lymphocytes(TIL) exercised their anti-cancerous clinical effect was not yet known.In preceding studies it had been seen that lymphocytes CD8+ managed to lyse autologous tumorsand alien tumors characterized by HLA restricted to the Major Hystocompatibility Complex of theFirst Class ( 376 ).In a later study ( 377 ) however, it was demonstrated, through the use of murine tumors, that it was,instead, the specific secretions of Interferon Gamma (IFN Gamma) by the TIL, that were theprinciple artifice of the immune response of the autologous tumor. From other studies it was thenobserved that the TIL deriving from contact with human melanomes and from carcinomas of thebreast secreted small quantities of GM-CSF (stimulation factors of the granulocyte colony and themacrophages), IFN Gamma and Tumoral Necrosis Factor Alfa (TNF Alfa), in response to alientumors specifically characterized by HLA ( 378-380 ). This demonstrated a precise interaction,restricted to the Major Hystocompatibility Complex, between T lymphocytes and cancerous cells.Studying, therefore, a series of TIL taken from the carcinomatous lesions of the human colon( 106,412 ), it was seen that these did not have a litic effect on the neo-plastic cells, yet it was possibleto recognize, by means of the Major Hystocompatibility Complex, the carcinomas of the colon(autologous or alien) marked with HLA. A subsequent study ( 279 ) showed that the expression of theMHC antigens, both of the first and the second class, could be reduced in carcinomas of the colon.In a further study ( 381 ), Rosenberg put forward the theory that the capacity of the TIL to secretecytokines, immediately after being stimulated by autologous and alien tumors, characterized byHLA, was due to a specific recognition on the part of a tumor-associated antigen, traceable even indifferent patients: this was the beginning of the official adoption of Immune Therapy.199

Chapter 9.b : Aloe arborescensAloe arborescensAmong all the medicines, phyto-medicines and active principles mentioned in this chapter, it isimportant to underline the recent use in medicine of a particular plant, which has been known sinceantiquity for its therapeutic properties: Aloe :( 146,149,164,179,189,211,225,267,273,314,333,372,387,388,392,393,465,487,499, 1117 ).Of the 250 known varieties, science has recently shown particular interest in Aloe arborescens, it isconsidered better than the other varieties of the plant including Aloe vera.Compared to the latter, in fact, Aloe arborescens has a higher concentration of active principles, atleast three times higher, and furthermore it is more resistant to our climate.It contains about a hundred active principles. Of the known substances, apart from 8 essential aminoacids, many vitamins, acetylsalicylic acid, choline and various forms of lipids, Aloe also containssome rare mineral salts: Zinc, Manganese, Iron, Germanium, Chromium, Magnesium, Boron, andSelenium, with important implications for the various human pathologies: among these, many of thedegenerative pathologies, the metabolism and deficiency diseases. Aloe arborescens tends tonormalize the biochemical and functional parameters of the organism in a time window whichvaries from 2 to 6 months:1) Regularization of partial pressure of carbon dioxide in the blood.2) Regularization of glucose values in the blood, particularly in diabetic patients.3) Reduction of triglyceride.4) Regularization of all cholesterol with an increase in the HDL/LDL ratio.5) Normalization of Bilirubin.6) Normalization of uric acid.7) Regularization of Na / K, Ca / Mg.8) An increase in hemoglobin.9) Protection of the gastro-intestinal, hepatic, pancreatic and kidney systems.10) Activation of the immune defenses against acute infections.11) A lymphocyte rebalance in chronic infectious diseases such as Hepatitis C, HIV/AIDS.12) An anti-oxidative protection of the DNA from the effects of ionizing radiation.Plants against AIDS : http://fiocco59.altervista.org/nacci/anti-AIDS%20plants.pdfIn particular some substances effective in the cure of tumors gain value ( 146,161-163,178,211,314,333,372,387-389,442,487,499 ), such as Anthraquinone Aloctin A, Aloctin B, and Emodin; the polysaccharides whichinclude Aloe-mannano; lecithin ATF1011 and Alexin B.These substances can be substantially divided into two groups with anti-cancerous action:1) Immune stimulation (the specific topic of this paragraph chapter 9.b)2) Apoptosis induction (Emodin-Aloe; SEE ALLEGATED).Immune stimulation1) The Aloctin A Anthraquinone (Aloctin A, Alo-A) and Aloctin B (otherwise known asBarbaloin), are contained in the external part of the leaves, and they are characterized bytheir laxative, bactericidal and anti-inflammation properties, in each case with completelysafe maximum tolerable dosages, that is equal to about 10 mg/ kg without any risk of realdamage to the patient. Their importance rests in the fact that they induce a high replicateactivity in the cytotoxic T lymphocytes and on the Natural Killers, in a way which iscomparable to other active factors already known. In particular, Aloctin A (Alo A) inducesactivation of IL-2,IL-3 and IFN gamma to minimum concentrations of 10 microgrammes200

mL ( 211 ). Furthermore it is thought to have the capacity to activate the Complement alongthe Via Alternativa ( 389,162 ).2) The polysaccharides, of a particular biochemical structure, are characterized by an extremefacility of absorption by the intestinal villus of the patient (if they are not undergoingchemotherapy). They are not mucopolysaccharides, because they do not contain nitrogengroups; among these, Aloe-mannano is of particular value, which acts in an antigen way,recalling at least in part the action of beta-Glucano (chapter 4d): structurally, it is a longacetyl and water soluble chain formed by mannose and glucose in a stoichiometrical ratio ofabout 6 to 1. As it is a molecule which is antigenically foreign to the organism, and thereforecapable, because of its particular polysaccharide conformation, of a higher capacity ofassimilation by the intestinal villus, it exerts, considering its relatively scarce concentration,its good capacity to induce an immune response in the T gamma-delta lymphocytes whichare present in about 150 lymph node stations of the intestine, with subsequent induction ofthe Immune Cascade (T lymphocytes are sensitized to the direct cytotoxic action [Tc], Killerlymphocytes [a cytotoxic action of the dependant-antibody mediated cell], Natural Killerlymphocytes [a cytotoxic action of the non dependant-antibody mediated cell] or bymacrophage-monocytes….): an Immune Cascade which would seem to be characterized, ata distance of 1-2 months from the beginning of oral administration of a mixture made up ofAloe arborescens (a ratio of 1 to 2 between freshly chopped Aloe and Honey) by a situationof diffuse Peritonitis starting from a gastric, ileum-caecal or hepatic point and lasting almosta week, followed by a haematic peak of lymphocytes in the absence of an increase in othersub-groups of white corpuscles (author’s personal observations).3) ATF1011It is a lecithin which connects to the surfaces of cancerous cells, thus inducing the activationof cytotoxic lymphocytes against them ( 499 ).4) Alexin BThe lecithin Alexin B has been tested and given positive results on lymphocyte leukaemia( 442 ).In anti-neoplastic therapy, it is of vital importance to choose plant therapies prepared with a base ofAloe which correspond to the following 10 requisites (as estimated by the author), otherwise thetherapy will fail, at least as is understood for the purposes of this study.1) the preparation must be made with a very high quality organic honey, avoiding, at all costs honey made from amix of flowers (‘millefiori’), a side product of other honeys. Honey is of primary importance because it carriesthe different immune-modulating substances of Aloe (Aloctin, Aloe-mannano, and Zinc) to the very delicate Tgamma-delta lymphocytes. The extreme vulnerability of these very delicate immune cells must be taken intoconsideration, and it is on them that, in substance, the whole immune Cascade response to the tumor depends(cytotoxic T lymphocytes, Killer, Natural Killer, macrophages, granulocytes etc). The honey itself, if is of apoor quality, could carry to the very delicate T lymphocytes, dangerous toxic-chemical substances such aspesticides.Furthermore, the Honey carries Emodin, vitamins and mineral salts, not easily activated even by the few tracesof toxic substances such as Chlorine, Fluoride, Iron, Copper and Alum (which are often in pharmaceuticalproducts), but also: Cadmium, pesticides, fertilizers, preservatives and chemical additives.2) The preparation must be made up from whole leaves of Aloe, and not only from the gel, because themorphology of the leaves consists of three very different materials, all pharmacologically useful: the outsidecuticle, which is green and has sharp pointed sides, formed by cellulous fibers; the intermediate pericyclic201

layer where the sap is yellowish and bitter (from which Anthraquinone Aloctin A and B , Emodin and evenAnthraquinone are derived); and finally the inside spongy tissue where the gel itself is (from which thepolysaccharides are derived including Aloe-mannano).3) The leaves must be taken from plants which are at least 3-4 years old, and must not include any of the centralleaves, that is, those which have a clear maculation, or any older leaves if they are too yellow, dry or broken.Young plants which have leaves with clear maculation must not be used.4) The leaves must be cut at the base, eliminating the tip, the base itself and the side thorns including the 4-5millimeter edge of the leaf. Each leaf must be cut cross-wise in 2 centimeter strips.5) The pieces of leaf must be liquidized with organic honey and a spirit (dry, distillated, not fermented, of goodquality, with no additives, such as for example: Grappa, eau de vie, Cognac or Whisky) in a container made ofa suitable material, that is with no aluminum or iron (which deactivate Vitamin E and other substances in theplant). The liquidizer could perhaps be made of stainless steel (a study currently in progress); it must besterilized by heat and not by using chemical disinfectants or other substances, such as chlorine (whichdeactivates different substances present in Aloe, even if there is just a trace used).6) The weight ratio between the leaf and the Honey must be 1:2 in the case of Aloe arborescens; and 3:2 in thecase of Aloe vera, because the latter is 3 times less rich in active principles compared to Aloe arborescens.Thus, for example, to 50-60 grams of Aloe arborescens leaves, 100-120 grams or up to a maximum of about150-200 grams of pure Honey must be added.Vice versa, with Aloe vera (the use of which is not advisable), at least 150-180 grams of leaves need to be usedbefore adding from 100-120 grams up to about 150-200 grams of pure Honey.In both cases, the spirit must be added, equal to 5-12 cc, until a homogenous cream is obtained.7) To the mixture, already prepared in a cream, should then be added Bis-carboxyle Germanium sesquioxide(organic Germanium), or inorganic Germanium can be added directly to the sandy soil where the plant isgrown, since it is well-known that enriching the soil with Germanium increases the therapeutic capacity of theplant, given the advantages we know about this element (SEE chapter 3).Note: inorganic Germanium is toxic. If it is absorbed by the plant it becomes organic (no longer toxic).8) Pour the contents into a glass container, sealing it well, write the date of the preparation and put it in a placewith a temperature of 4°C (the standard temperature of a fridge), and away from the light (the active factorswill become deactivated quickly both in the light and in a normal temperature).9) Even kept in the dark and the cold, the active ingredients will deteriorate in a few weeks. Therefore it isadvisable to consume the mixture within 1-2 months maximum after preparation.10) Aloe arborescens contains a higher percentage of active principles then Aloe vera. Therefore it is advisable tocultivate Aloe arborescens (orange flower) rather than Aloe vera. If possible, it is best to use a soil mixed withsand.According to the author, the several spoonfuls of Aloe arborescens with organic Honey must betaken at the usual hours advised (half an hour before breakfast, lunch and dinner).Aloe arborescens has also been experimented using a dosage of two tablespoonfuls every 2-3 hours,up to a total of 18-20 doses daily, in more serious cases.In the anti-cancer protocol (chap. 16), Aloe arborescens must, however, be integrated with 10-15portions of fresh fruit and raw vegetables, Allium sativum and Allium cepa for Germanium 132(SEE chapter 3), 1-2 gramms of Ananas sativus stalk (Bromelain) with (bitter) seeds of Prunusarmeniaca (or spinosa, or avium, or domestica), 20-40 types of medicals plants (SEE chap.6 andchap.9) organic whole-wheat pasta (without Lysine and Tripthophan).Note : for all cultivated forms of Aloe, leaves and derivatives, particular attention must be paid tothe different types of plant, bearing in mind that Aloe vera contains 1/3 less active principles thanAloe arborescens. In particular, attention must be paid to leaves deriving from plants which are notsuitable, such as “Aloe from Natal”, a serious sophistication of the product because it containsOmonataloin: C –glucosydes of 1,7 dihydroxy-8-methodoxy-3 methyl ( 580 ).202

Chapter 9.c : ESSIACFrom INTERNET: Herbal Therapies for Cancer, by Vivekan Don Flint and Michael Lerner, Research Assistance:Melanie Smith, October 1997.(NON reported in Italian version of commercial Book “Diventa Medico di te stesso !”)Essiac is an herbal preparation, reportedly based upon a Native American formula, that has been in use widespread bypeople with cancer since the 1920s.Rene Caisse, a nurse at a rural clinic in Ontario, Canada, was told by one of her patients that she had recovered from abreast cancer 20 years earlier after using an Indian herbal tea. Caisse obtained the recipe for the tea from the woman andbegan giving it to patients in 1924 after reportedly using it successfully with an aunt with cancer ( 1438 ).Cassie's life and work are the subject of two extremely sympathetic biographies, The Calling of An Angel ( 1439 ) by GaryGlum and The Essiac Report: Canada's Remarkable Unknown Cancer Remedy( 1440 ) by Richard Thomas.According to Thomas, Caisse, working with her aunt's physician, R.O. Fischer, M.D., reasoned that even better resultsmight be obtained by injecting the herbal preparation. Working with mice inoculated with human cancers, theydetermined which herbs could be safely injected:It took Dr. Fischer and I about two years to find out just what ingredients could be given hypodermically without areaction, and by elimination we found the ingredients that directly reduced the growth of the cancer. However, I foundthat the other ingredients, which could not be injected, were necessary to the treatment in order to carry off thedestroyed tissue and infections thrown off by the malignancy. So by giving the injection to destroy the mass ofmalignant cells and giving the medicine orally to purify the blood, I was able to get the best results.( 1441 ).Caisse believed that even if the tumor did not disappear completely, it could be forced to regress to the point that itcould be surgically removed after six to eight treatments. Then, if there were any suspicion that malignant cells mightbe left after the operation, she recommended that Essiac be given once a week for at least three months thereafter ( 1442 ).It was during this time the formula was given the name Essiac, Caisse spelled backwards.Soon Caisse was reportedly treating as many as 30 people a day out of her mother's Bracebridge home. Then, in 1935,the Town of Bracebridge turned over a repossessed hotel to Caisse for use as a clinic. She treated many hundreds ofpatients there and received a great deal of attention in the press for her reported successes.In 1938, supporters circulated a petition garnering 55,000 signatures in support of Caisse's practice, which operated intechnical violation of Canadian law. Sympathetic legislators introduced a bill to authorize Caisse to practice medicine inOntario. The competing "Kirby Bill" proposed instead setting up a Royal commission to investigate "controversial"treatments before allowing treatment of patients and require all formulas to be turned over to the Commission.Caisse, who reportedly treated patients without regard to ability to pay, was adamantly opposed to surrendering theformula for Essiac fearing patients would be exploited. Nevertheless, the bill to legalize her practice lost by three votes.Caisse's threat to close her clinic brought a public outcry and the Health Minister assured her she would not be chargedunder the new Kirby law ( 1443 ).In 1938, the Royal Cancer Commission initiated an investigation by visiting her clinic to interview patients. The visitwas followed by a public hearing in 1939 attended by 387 patients who came to testify on Caisse's behalf. However,only forty-nine patients ultimately were allowed to testify. In most cases the commission decided it was unclear whetherconventional therapy or Essiac was responsible for improvement, and in many cases whether the diagnosis of cancerwas even accurate. The commission concluded that of eight patients whose diagnoses could be confirmed, two of thefour recoveries could be credited to Essiac. The Commission concluded that "the evidence adduced does not justify anyfavorable conclusion as to the merits of 'Essiac' as a remedy for cancer..."Despite the unfavorable ruling, Caisse continued to treat patients, but became increasingly fearful of prosecution. Sheclosed her clinic in 1942, though she continued to treat patients in secrecy from her home ( 1444 ).The [OAM] summary of Essiac research describes a 1958 study conducted at Memorial Sloan-Kettering Cancer Center(MSKCC) in which "some changes" were observed in mice treated with Essiac that were not observed in controls.MSKCC requested the formula in order to pursue further testing, but Caisse refused the request ( 1445 ).203

In 1959, Caisse travelled to the Brusch Clinic in Cambridge, Massachusetts to work with Dr. Charles Brusch on aclinical evaluation of Essiac. Brusch was a highly regarded physician and President Kennedy's personal doctor. He alsohad a keen interest in unconventional medicine, having established the first clinic in the United States to conductresearch on acupuncture.After using Essiac with patients at the clinic for three months, Brusch wrote:Clinically, on patients suffering from pathologically proven cancer, it reduces pain and causes a recession in growth;patients have gained weight and shown an improvement in their general health. This after only three months' tests andthe proof Miss Caisse has to show of the many patients she has benefitted in the past 25 years, has convinced thedoctors at the Brusch Medical Center that Essiac has merit in the treatment of cancer. The doctors do not say thatEssiac is a cure, but they do say it is of benefit. It is non-toxic, and is administered both orally and by intramuscularinjection ( 1446 ).The OAM reports, however, that the results of studies on 35 mice and an unknown number of patients at the clinic havenever been published ( 1447 ).Researchers at both Memorial Sloan-Kettering Cancer Center (MSKCC) and the NCI expressed interest in testingEssiac, but Caisse refused to reveal the formula. But clinical research continued at the Brusch Clinic, and incollaboration with herbalist Elmer Grove, Caisse and Brusch added additional herbs, feeling they had potentiated theformula to the point it no longer needed to be injected, but could be taken orally ( 1448 ).In 1973, Caisse contacted MSKCC concerning the possibility of further testing with Essiac. Caisse supplied Essiac forthe next three years for tests in mice.According to the OTA:Caisse submitted three samples of Essiac (two dried samples used to make an extract and one liquid sample), whichMSKCC tested in the S-180 mouse sarcoma test system. This test is intended to detect immunotherapeutic effects(indicated by the occurrence of tumor regression) or chemotherapeutic effects (indicated by a diminished tumor growthrate). The results of six immunotherapy tests and two chemotherapy tests of Essiac samples using the S-180 system allshowed no activity ( 1449 ).These disappointing results led to accusations by Caisse of improperly prepared Essiac and the implantation of animalrather than human carcinoma in the mice ( 1450 ).The controversy around Essiac surfaced publicly again in Canada in 1977 when Homemakers Magazine, a widely readnational publication, printed an exhaustively-researched article about Caisse and Essiac describing numerous casehistories. The management of the publication also offered to set up a trust for Caisse "to represent her in any dealingsshe might have with the government, Cancer Institute or any interested pharmaceutical companies," an offer she refused( 1451 ).One of the results of the renewed interest in Essiac was an offer from the Resperin Corporation to open five fullystaffedclinics to offer Essiac free of charge to those who could not afford the proposed price of the therapy if she wouldgrant the corporation exclusive rights to the formula. Resperin also offered to test Essiac in formal clinical trials withhuman subjects. Caisse accepted the offer and provided Resperin with the formula for Essiac ( 1451 ).In 1978, Resperin filed a "preclinical new drug submission" with Health and Welfare Canada which would haveallowed clinical trials with human subjects to proceed. The submission was suspended in 1982 by the Health ProtectionBranch (HPB) because Resperin failed to fulfill the agreement "to maintain adequate manufacturing, to investigate thepharmacology of Essiac, and to arrange the appropriate clinical trials."( 1452 ).MSKCC tested Resperin's sample of Essiac in a variety of other animal leukaemia and solid tumor test systems in 17separate chemotherapy experiments and found no antitumor activity in any of these tests. No evidence of acute toxicitywas found, although some evidence of subacute toxicity (slight weight loss in treated animal) was observed ( 1453 ).Likewise, the NCI tests conducted at the request of the Health Protection Branch of Health and Welfare Canada on aliquid sample of Essiac submitted by the Resperin Corporation showed no effect in a mouse lymphocytic leukaemiasystem. Unlike the MSKCC tests, the NCI tests found lethal toxicity at the highest levels given to animals. It is notknown how the composition of the samples tested by MSKCC compared with those given to the NCI or how theconcentrations used in the animal tests relate to treatments given to patients ( 1454, 1455 )204

During the same period of time, Resperin applied to the FDA for permission to market Essiac in the United States andwas turned down. Details of such submissions are confidential, so the circumstances of the denial are unavailable ( 1456 ).In early 1980, Canadian health officials conducted a retrospective review of Canadian patients treated with Essiac usingcase summaries submitted voluntarily by the patients' physicians.According to the report:In 1982, 112 physicians who had received Essiac...were asked to submit case reports. Seventy-four responded on 87patients. Of these, 78 showed no benefit.Investigation of the nine remaining cases revealed that the cancer was progressing (four cases) the patient had died(two cases) or that the disease had stabilized (three cases).Of this last group, all the patients had previously undergone some form of cancer treatment which could have stabilizedthe disease ( 1457 ).It was also noted that some of the patients might have benefitted psychologically or emotionally from the treatment.Few patients reported any serious side effects other than occasional nausea vomiting that was attributed to a "variationin composition" of the preparation ( 1458 ).Critics of this study cite numerous unanswered questions, such as whether the patients who "received no benefit"experienced a reduction in pain or increased appetite, whether the herbs were properly handled and the formulaprepared properly, or whether the formula was given orally or by injection ( 1459 ).During the preparation of the 1990 [Report on Unconventional Cancer Therapies], the OTA requested the details ofthese voluntary physician reports from the Canadian government but was told that the information was not available( 1460 ).However, in 1983, around the time of the Canadian government report, Dr. E. Bruce Henrick, Chief of Neurosurgery atthe University of Toronto's Hospital for Sick Children, urged Canadian health officials to initiate clinical trials ofEssiac, stating in a letter to the Canadian Minister of Health and Welfare that eight of ten patients with surgically treatedtumors of the central nervous system had "escaped the conventional methods of therapy including both radiation andchemotherapy" by following an Essiac regimen ( 1461 ).Though the research using Essiac in animals and humans is inconclusive, some research does exist on the anticancerproperties of its various constituent herbs, though many herbalists maintain that it may be the synergistic effect of herbsin combination that is largely responsible for any observed benefit. As we have noted, Caisse did not believe that all theconstituent herbs in Essiac acted directly on the tumor, but that some served other functions, such as detoxification andelimination.Burdock (Arctium lappa)Burdock root is a key ingredient in another herbal formula for cancer, the Hoxsey Therapy, as well as a staple in theJapanese and macrobiotic diets. According to the Office of Alternative Medicine report on Unconventional CancerTreatments, burdock has historically been used against tumors in several countries: China (in a record from 502 A.D.),Japan, Italy (in the twelfth century), Spain, and Chile. A related species, lesser burdock, was employed as an antitumoragent by the Potawatomi Indians in the Midwest ( 1462 ).The OTA reports two studies showing antitumor activity with burdock in animal tumor systems, with various fractionsinhibiting Yoshima sarcoma in mice by as much as 61 percent ( 1463-1465 ). It also reports that the NCI has tested burdock14 times, with one sample showing activity, though not considered significant, in the P388 mouse leukaemia model.The OTA also lists two other studies in animals which found no antitumor activity with Arctium lappa ( 1466-1468 ).Japanese researchers tested Arctium lappa (burdock) and nine other vegetable juices for their ability to preventchemically-induced chromosomal mutations in rat bone marrow cells. Significant suppression of the incidence ofmutations was found using the fresh or boiled juice from onion, burdock, egg plant, cabbage and welsh onion ( 1469 ).Arctium lappa (burdock) was also found by another team of Japanese researchers to reduce the mutagenicity ofchemicals activated by the metabolism, as well as those whose mutagenicity is not dependant upon metabolic activity.205

Purification of the "burdock factor" increased its effectiveness and reduced the level of mutagens by 24 percent,whereas fresh juice reduced mutagens by 17 percent ( 1470 ).Benzaldehyde, which has been isolated from burdock, has also shown anticancer activity in some animal tests,described in the section on laetrile.Arctium lappa seed (Burdock) contains a number of ligands, including arctigenin, which has been shown to inducedifferentiation in mouse myeloid leukaemia (M1) cells. In their report on their studies of terminal differentiating agentsfrom methanolic extracts of over 200 plants tested, Kaoru Umehara and his colleagues at the University of Shizuokafound that burdock seeds showed a marked differentiation-inducing activity toward M1 cells at very low concentrations,though they were inactive towards a human promyelocytic leukaemia cell line ( 1471 ).Arctigenin has also demonstrated potent cytoxic effects against another human leukaemia cell line while showing notoxicity to normal lymphocytes. Arctigenin was less effective in inhibiting the growth of a human T lymphocyticleukaemia cell line ( 1472 )At least two cases of poisoning have been reported from the consumption of commercial burdock teas in the UnitedStates ( 1473-1475 ) though the OAM reports that one of these was later found to be attributable to an additive that containedAtropine ( 1476-1479 ).Sheep Sorrel (Rumex acetosa)The OTA reports that the NCI tested one sample of sorrel from Taiwan and found no activity in the mouse leukaemiamodel. Aloe Emodin and Emodin have been isolated from sorrel and have shown antitumor activity in some animal testsystems ( 1480 ).In one study, a Japanese researcher found that Rumex acetosa polysaccharide displayed antitumor activity in miceimplanted with Sarcoma 180 solid tumors ( 1481 ).Slippery Elm (Ulmus fulva)According to the OTA, the NCI tested slippery elm seven times using samples from various parts of the United Statesand found no activity in mouse leukaemia systems. Slippery elm contains betasitosterol and a polysaccharide shown tohave antitumor activity in animal models ( 1482 ).Indian Rhubarb (Rheum palmatum)The OTA reports that Indian rhubarb was found to have antitumor activity at one dose level in the Sarcoma 37 animalsystem, but not at a higher dose in the same system ( 1483 ). Another group found Rheum palmatum to be inactive in twoother animal tumor systems ( 1484 ). The OTA also reports that the NCI tested two samples of Rheum palmatum fromPoland and found no antitumor activity in mouse leukaemia systems. Another variety was tested three times by the NCIand again no activity was found in the mouse leukaemia system. However, some components of Rheum palmatum(Aloe Emodin, Catechin, Emodin and Rhein) have shown antitumor activity in some animal systems ( 1485-1487 ).According to Boik, rhein is of particular interest in this regard. Rhein is a compound found in a number of purgativeherbs that is largely responsible for their activity. Boik discusses research on the antitumor properties of Rhein, whichseems to disrupt protein synthesis in neoplastic cells ( 1486-1487 ). Other studies indicate that it may be most effective whenthe exposure is prolonged, with an exponential relationship between cell kill rate and Rhein concentration up to 20hours, and a linear relationship thereafter ( 1488-1490 ). In other research cited by Boik, Rhein has also shown antitumoractivity in vivo, increasing survival time in P388 leukaemia bearing mice in one study and inhibiting melanoma in miceby 76 percent in another ( 1491-1492 ).Today, the situation for the cancer patient interested in using Essiac is bewildering at best. Numerous "competing"formulas are on the market, each manufacturer claiming to have to have the version that Caisse used.In Gary Glum's biography of Caisse, The Calling of An Angel, he states that he obtained the formula for Essiac from awoman who had achieved total remission from cancer using the formula given to her in writing by Caisse. Glummaintains that he authenticated the formula with Mary McPherson, a close friend of Caisse's, whose mother wasreportedly cured of cancer by Essiac. Richard Walters, author of Choices: The Alternative Therapy Handbook statesthat although McPherson confirmed the authenticity of Glum's formula, she also stated that Caisse occasionally variedthe formula.206

According to Walters, Glum's critics contend that the formula he gives in an instruction sheet accompanying his bookare inaccurate. They charge that it is missing at least one key ingredient and is drastically off in the ratios of the variousherbs. These critics allege that Glum's version of Essiac is not the true Essiac and that it is potentially harmful topatients ( 1493 ).Walters also reports that Sheila Snow, coauthor of the 1977 Homemaker's article, believes Glum's version of Essiac "isthe recipe Rene used in the 1930's when she prepared the remedy in her Bracebridge clinic for hundreds of patients,and quite conceivably the one passed along to the Resperin Corporation for its clinical studies."( 1493 ).In 1988, Charles Brusch, who claimed to have treated his own cancer using Essiac, entered into a partnership withElaine Alexander, a Vancouver, British Columbia, radio talk show host who had interviewed him several times, tocircumvent the law and market Essiac as a "detoxification tea" under a different name. Flora Manufacturing andDistributing Ltd. was chosen in 1992 to market the product under the brand name Flor Essence ( 1494 ).According to Walters, Alexander believed that the method of preparation, ratios of ingredients and correct dosages wereall essential to Essiac's efficacy. She stated that Caisse continually improved on the Essiac formula over the years andthat Glum's version may be an "early, primitive version" of a formula Caisse later improved upon. She also believedthat various "specious facsimiles" of Essiac that are available on the market could be dangerous to patients ( 1495 ).The fact remains that there is no information available how Caisse used Essiac for specific cancers or whether allpatients received the same formula and dosages. Further, neither Caisse nor her supporters ever published their researchon the formula in animals or humans.Although Essiac is unapproved for marketing in Canada, the Canadian government allows Essiac to be manufactured,sold and used by cancer patients under certain circumstances. A cooperative arrangement between Resperin and theHealth Protection Bureau authorizes the sale of Essiac to cancer patients on "compassionate grounds" when no othertreatment is appropriate.Today, according to the Office of Alternative Medicine, Flora, Resperin, Essiac International, Glum, and HerbalEssence are the major suppliers of Essiac. The OAM estimates that the annual cost for one to four ounces of liquidEssiac to range from $527 to $2060. The annual cost for dry herbs is estimated to be in the range of $100 to $400, ( 1496 )making Essiac a relatively inexpensive therapy with a contradictory research record and legions of patients over theyears who feel they have received some benefit from it, either in terms of anticancer activity or quality of life benefits.207

Chapter 9. d :Other plants with an immune stimulating activityThere are about sixty other immune modulating plants from North America and Europe, with anaction which is partially similar to Aloe arborescens, seven of which can be included in the517, 520,1047-composition termed Essiac ( a formula of Renè Caisse) which is particularly effective (1060, 1438-1496 ).There are also some interesting combinations of about 200 Indian plants and herbs of ancient Vedic,Chinese tradition ( 608-609 ), of Africa and of Sud-America, used today in modern western planttherapy which has revalued their importance ( 621,773,793,794 ).Among the different plants the following deserve notice:1) Arctium lappa (great burdock, bardana): the roots from the first year of growth must be usedin autumn, and in spring of the second year before the flowers come out (they have both animmune–stimulating and an antibiotic effect);2) Rumex acetosa (sorrel, acetosa): use all the plant before it flowers in its second year; it isparticularly rich in vitamin C, it may however be the cause of kidney stones (it is thereforeuseful for the patient to also take common Magnesium, possibly with vegetables).3) Rheum palmatum (chinese rhubarb): use the roots of the old plants with the peridermremoved; the chrystphanic acid could have a certain anti-cancerous action; it has similarcomponents to those of Aloe (Aloe-Emodin).4) Trifolium rubeus (red trefoil): use the flowers for their 4 anti-cancerous substances: Genistin(suspected of inhibiting growth), Daidzein, Formonetin and Biocanin; note:OGM-risk( 1066 )5) Viscum album (mistletoe) usually injected under the skin (note: it has adverse side effects oncardiopathic patients).Another:1) Uncaria tomentosa2) Bambusa arundinacea.3) Echinacea purpurea, angustifolia, or pallida4) Astragalus membranaceus.5) Grindelia camporum or squarrosa6) Tribulus terrestris7) Plantago major8) Scutellaria baicalensis o latiflora9) Asparagus cochinensis10) Ulmus rubra or fulva11) Rhodiola rosea12) Nelumbo nucifera13) Xanthoxilum fraxineuem14) Artemisia abrotanum15) Artemisia dracunculus16) Campanula latifolia17) Acalypha indica18) Equisetum arvense19) Hypoxis hemerocallidea20) Salvia officinalis21) Citrus aurantium bergamia22) Cassia angustifolia208

23) Rhamnus sagrada or purshiana24) Rhamnus frangula or Frangula alnus25) Picramnia antidesma26) Terminalia chebula27) Angelica archangelica28) Abuta grandifolia29) Urtica dioica30) Thymus vulgaris31) Larrea mexicana32) Primula veris or officinalis33) Ailanthus glandulosa34) Citrullus colocynthis35) Thymus serpillum36) Viola tricolor37) Taraxacum officinalis38) Rosmarinus officinalis39) Sysymbrium officinale40) Sticta pulmonaria or Lobaria pulmonaria41) Cinnamomum zeylanicum42) Polygala senega43) Nepeta cataria44) Adiantum capillus veneris45) Tephorosia purpurea46) Eclipta alba47) Argyreia speciosa (or Lettsomia nervosa)48) Aquilaria agallocha49) Argemone mexicana50) Glycyrrhiza glabra51) Althaea officinalis52) Annona squamosa or muricata53) Momordica charantia54) Albizzia lebbek55) Apium graveolens56) Moringa pterygosperma57) Holarrhena antidysenterica58) Verbascum densiflorum or thapsus59) Sambucus nigra60) Euspongia officinalis61) Smilax aspera, sarsaparilla or utilitis62) Serenoa repens63) Myrica cerifera64) Luffa operculata65) Rumex crispus66) Myristica fragrans or sebifera67) Galphimia glauca68) Lycopodium clavatum69) Eupatorium perfoliatum70) Eupatorium purpureum71) Ocimum sanctum or tenuiflorum72) Ocimum basilicum73) Mahonia aquifolium209

74) Calendula officinalis75) Chimaphila umbellata76) Ceanothus americanus.77) Drosera rotundifolia, or anglica, or intermedia78) Curcuma longa79) Trigonella foenum graecum80) Morinda citrifolia81) Aralia racemosa82) Asparagus racemosus83) Ailantus glandulosa84) Sutherlandia frutescens85) Lepidium meyenii86) Tabebuia impetiginosa87) Stachys arvensis88) Polygonum aviculare89) Melissa monarda or officinalis90) Crataegus oxyacantha or monogyna91) Pulmonaria officinalis92) Pulmonaria angustifolia93) Azadirachta indica94) Bacopa monnieri95) Alchimilla alpina or vulgaris96) Boswellia serrata97) Lamium album98) Pimpinella major99) Acorus calamus100) Galium aparine101) Ajuga reptans or piramidalis102) Marrubium vulgare103) Lysimachia nummularia104) Lapsana communis105) Primula hirsuta106) Peucedanum ostruthium107) Sempervivum montanum108) Saxifraga oppositifolia109) Saxifraga aizoides110) Pedicularis rostrato-capitata111) Potentilla grandiflora112) Leucanthemopsis alpina113) Hypericum richeri114) Gentiana germanica115) Hieracium pilosella116) Gnafalium supinum117) Cicerbita alpina118) Draba aizoides119) Cerastium alpinum120) Antennaria dioica121) Antyllis alpestris122) Marasdenia cundurango123) Myrtus communis124) Melaleuca alternifoglia210

125) Cinchona calisaya or succirubra126) Cetraria islandica or Lichen islandicus127) Glechoma hederaceum128) Centaurea erythreum129) Meum mutellina130) Epilobium angustifolium131) Erithrea antaurium132) Myroxylon balsamum133) Larrea divaricata134) Capsella bursa pastoris135) Achyrocline satureoides136) Polypodium lepidopteris137) Anacardium occidentale138) Bidens pilosa139) Bixa orellana140) Carapa guianensis141) Boerhaavia diffusa142) Calendula silvestis143) Cassia occidentalis144) Cayaponia tayuya145) Cissampelos pareira146) Copaifera officinalis147) Cynara scolymus148) Erythrina mulungu149) Houttuynia cordata150) Erythroxylum catuaba151) Ilex paraguariensis152) Inesinae calea153) Lepidium meyenii154) Maytenus krukovit155) Maytenus illicifolia156) Myroxylon balsamum aut pereirae157) Pfaffia paniculata158) Phyllantus niruri159) Physalis angulata aut Muehenbeckia volcanica160) Psidium guajava161) Schinus molle162) Solanum paniculatumOf these plants, there are at least 8 with phyto-therapeutic components similar to those of Aloespecies: Rhamnus frangula or Frangula alnus ( 239 ), Picramnia antidesma ( 612 ), Rhamnus sagradaand purshiana, Rubia tinctorium or peregrina, Rheum palmatum or officinale( 247 ), Terminaliachebula, Cassia angustifolia ( 613 ) and Tabebuia cassinoidesAccording to the orhor, these plants should be integrated into the diet of the patient (they should befreshly picked from the vegetable garden, washed well and eaten raw).211

Phyllantus niruri (Chanca piedra, Spaccapietra)There is an extensive bibliography on the action of this plant ( 793,925-941 ).“Chandra piedra” means “stone breaker, or shatter stone. It has been called stone breaker because ithas been used for generations by the indigenous peoples of the Amazon as an effective remedy toeliminate gallstones and kidney stones and for other kidney problems.The plant is employed for numerous other conditions, including blennorrhagia, colic, diabetes,dysentery, fever, flu, tumors, jaundice, vaginitis, and dyspepsia. It is little wonder that Phyllantusniruri is used for so many purposes, since the plant has demonstrated antihepatotoxic,antispasmodic, antiviral, antibacterial, diuretic, febrifugal, and hypoglycemic activities. It is alsoknown as an anodyne, aperif, carminative, digestive, emmenagogue, laxative, stomachic, tonic, andvermifuge, based on its long, documented history of uses.Its considered an excellent remedy for removing uric acid from the urine and eliminating stones.. Itsalso used for hydropsy, urinary and bladder infections and blockages, liver ailments, painful joints,cystitis, prostate disorders, kidney disorders, hepatitis, diabetes and as an antispasmodic and musclerelaxant specific to the urinary tract system. In India, its a common household remedy for asthmaand bronchitis and is used to treat coughing, extreme thirst, anemia, jaundice, and tuberculosis.The antihepatotoxic (liver-protecting) activity of Phyllantus niruri was attributed to two compoundsin the plant, Phyllanthin and Hypophyllanthin, in a 1985 study by Indian researchers. Glycosidesfound in Phyllantus niruri demonstrated aldose reductase inhibitory activity in studies conducted bya Japanese research group in 1988 and 1989. The analgesic activity of Phyllantus niruri wasdemonstrated in 1994 and 1995 by another research group in Brazil. The diuretic, hypotensive andhypoglicemic effects of Phyllantus niruri were documented in a small, ope human study conducedin 1995. This study showed a significant diuretic effect, a significant reduction in systolic bloodpressure in nondiabetic hypertensives and female subjects, and a significant reduction in bloodglucose in diabetic patients taking Phyllantus niruri for 10 days.Preliminary clinicals trials on children with infective hepatitis using an Indian drug containingPhyllantus niruri as the main ingredient showed promising results that fueled the subsequent invitro and in vivo studies. The in vitro inactivation of hepatitis B by Phyllantus niruri was reportedin India in 1982.A study that followed indicated that in vivo Phyllantus niruri eliminated hepatitis Bin Mammals within 3 to 6 weeks.Other research, conducted from 1990 to 1995 has indicated thatPhyllantus niruri does demonstrate anviral activity against hepatitis B.The most recent research onPhyllantus niruri reveals that its antiviral activity extends to Human Immunodeficiency Virus(HIV). A Japanese research group discovered Phyllantus niruri’s HIV-1 reverse transcriptaseinhibition properties in 1992 with a simple water extract of the plant. A Pharmaceutical Instituteisolated at least one of the constituents in the plant responsible for this activity, a novel compoundthat they named niruriside and described in a 1996 study.Hypoxis hemerocallidea (Hypoxidaceae)The “African potato” comes from the forests of Kwa Zulu Natal and Pondoland.. The activeprinciples of this plant include Sitosterol and Sitosteroline, together with an anti-tumoral phenoliccomponent: hypoxide. Sitosterol and Sitosteroline have a proven beneficial effect on the humanimmune system. Prof. Ben Smith, consultant in the oncology department of the Tygerberg Hospitalin Cape Town, has treated patients with advanced tumors discovering that this has increased hopesof survival. Patients who suffer from tumors of the pancreas usually die within 4-6 months ofdiagnosis, but after therapy based on Sterol, taken from the plant, they have survived for a year ormore, with relief from the unpleasant side effects of Chemo-Therapy.N.B. Hypoxide contains 2 molecules of glucose, an apoptosis action is suspected.212

Viscum album (Mistletoe)48, 49, 116, 152, 153,With regard to Viscum album, of which there are beginning to be interesting reports (252, 271,498 ), the author would also like to report a simple personal observation regarding the case of apatient of advanced years with a bilateral lung tumor in a pleural direction which went intocomplete remission in four months on the basis of subcutaneous injections of this substance, withabsolutely no chemotherapy, radiotherapy or surgery (confidential data).From other data in literature, it has been reported that after 24 hours of administering this substance,in general, there is an increase in the number and the activity of Natural Killers ( 152 ) and theinterleuchines, the tumoral Necrosis Factor and the activity of the macrophages increase ( 271 ).Note : Viscum album (mistletoe) can cause orthostatic hypertension and strong bradycardia; itcannot be used in patients who suffer from serious bradycardia or blocks of the sinuatrials or thebranchia ventricular atrium.Maytenus krukovit, laevis, macrocarpa, ebenifolia (Chuchuhuasi)There is an extensive bibliography on the action of Maytenus krukovit, laevis, macrocarpa,ebenifolia ( 793,824-829 ).In the 1960s it discovered its potent immune-stimulating properties, finding that it dramaticallyincreased phagocytosis in mice. In the mid-1970s Italian researchers studying a chuchuhuasi extractused effectively to treat skin cancers identified its antitumor properties.Its antiinflammatory properties were discovered in the 1980s by another Italian research group.They discovered that its anti-inflammatory properties, radiation protectant action, and antitumorproperties were at least partially linked to triterpenes and antioxidants isolated in the trunk bark. In1993 a Japanese research group isolated a group of novel alkaloids in Maytenus species that may beresponsible for its effectiveness in treating arthritis and rheumatism. In the United States apharmaceutical company studying chuchuhuasi’s anti-inflammatory and anti-arthritic properties hasdetermined that these alkaloids can effectively inhibit enzyme production of protein kinase C(PKC).PKC inhibitors have been of much interest worldwide because there is evidence that too much ofthis enzyme is involved in a wide variety of disease processes, including arthritis, ashtma, braintumors, cancer, and casrdiovascular disease.Achyrocline satureoides (Macela)There is an extensive bibliography on the action of Achyrocline satureoides ( 793,855-863 ).Achyrocline satureoides has been of recent clinical interest and its uses in natural medicine havebeen validated by science since the mid-1980s.In animal studies with mice and rats, macela demonstrated analgesic, anti-inflammatory, andsmooth muscle-relaxant properties internally (gastrointestinal muscles) and externally withouttoxicity. This may well explain why Achyrocline satureoides has long been used effectively formany types of gastrointestinal difficulties as well as asthma. In vitro studies have demonstrated thatmacela is molluscicidal, and mutagenic against Salmonella and E.coli, which could explain its usesagainst dysentery, diarrhea, and infections.Other research on macela has concentrated on its anti-tumorous , antiviral, and immuno-stimulantproperties. It was shown to pass the initial anti-crustacean screening test used to predict antitumoractivity in 1993. In the mid-1980s German researchers extracted the whole dried plant anddemonstrated that in humans and mice it showed strong immuno-stimulant activity by increasingphagocytosis. They isolated a plysaccharide fraction in the Achyrocline satureoides extract thatseemed to be resonsible for this effect. In the mid-1990s Japanese researchers showed that anextract of Achyrocline satureoides flowers inhibited the growth of cancer cells by 67% in vitro.213

In 1996 researchers in Texas found that a hot water extract of dried Macela flowers demonstrated invitro antiviral properties against T-lymphoblastoid cells infected with HIV.Morinda citrifoliaIt is a shrub of equatorial Africa, South-East Asia, Polynesia and the Caribbean, it is known by anumber of names (Bumbo africano, Gelso indiano, Gran Morinda, Lada, Mengkudo, Nhau, Nonu,Noni, Nono). An immune-modulating substance has been found in its fruit ( 577 ), alongside otherparticularly interesting molecules for other anti-neo-plastic activities, still being studied.Physalis angulata (Mullaca)There is an extensive bibliography on the action of Physalis angulata ( 793,864-872 ).Pytochemical studies on Physalis angulata reveal that it contains flavonoids, alkaloids, and manydifferent types of plant steroids, some of which have never been seen before in science. Physalisangulata has been the subject of recent clinical research that is still ongoing, based on preliminarystudies showing that it is an effective immune stimulant, is cytotoxic to numerous types of cancercells, and has antiviral properties, including against HIV. The new steroids found in Physalisangulata have received the most attention, and many of the documented properties and actions areattributed to these steroids. In several in vivo animal tests and in vitro lab tests, an extract of theentire plant of Physalis angulata and / or its steroidal fractions demonstrated immune stimulantproperties by strongly enhancing blastogenesis, antibody responses, and increased T and Blymphocyte production. Various water, alcohol, and ethanol extract of Physalis angulata and itsplant steroids have shown strong in vitro and in in vivo cytotoxic activity against numerous types ofcancer cells, including leukaemia, lung, colon, cervix, and melanomas.Panax ginsengPanax ginseng is also the subject of many studies ( 502-506,576 ).It is characterized by a certain immune stimulating action, particularly on T lymphocytes.It grows naturally in shady areas in the mountains. It is particularly widespread in Korea, but is alsofound in Japan and China. It has been studied recently in Canada and the United States.It contains organic Germanium (SEE chapter 3).There are many products of this on sale. Its value depends on the fact that it is cultivated without theuse of fertilizers or chemical substances. It is advisable to use the gel extracted from ginseng with asuitable percentage of ginsenoids (from a minimum of 8% to a maximum of 12%). It is counterindicatedin the case of hypertension and of prostatic hypertrophy.Uncaria tomentosaIn May 1994, the WHO called the first International Conference on this plant, recognizing it as amedicinal plant( 714,753-773 ). Various alkaloid ossindolics have been extracted from its bark and itsroots (such as Pteropodin, Specrofillin, Hystopteropodin, Uncaria F and Isomitrofillin). They havean immune-stimulating character, having been tested with a positive result on leukaemia cells (witha apoptotic or pseudo-apoptotic action). Glucosydes of chinovic acid (Chinoline) are also present.Other substances contained therein have an anti-inflammatory, hypertensive and vasodilatory effect.N.B. it also inhibits telomerasic activity (characteristic of about 90% of tumors known in humans,and induced apoptosis on tumor (SEE chapter 5).214

Tabebuia impetiginosaThe suspected anti-neo-plastic activity of the pulverized inner bark of Tabebuia impetiginosa, aplant known in central America has not yet been clarified in medical literature ("Pau d'Arco", IpeRoxo", "Taheebo", "Lapacho"). As well as an almost certain immune stimulating action, we couldalso add the activity of the lapocoic acid extracted from its wood, which would seem to have aparticular bio-chemio-therapeutic property on cancerous cells cultivated in vitro (SEE also chapter5); Xiliodone is another of its principle actives and would seem to be effective against Candidaalbicans (SEE chapter 5).Abuta grandifogliaAbuta contains palmatin (hypo-tensive and a sedative); bis-benzil-isoquinolinic alkaloids (antiinflammatoryagents acting on nitric oxide); and three particular molecules: Tetrandrin, Parirubin Aand Parirubin B. Tetrandrin has the following actions: analgesic, anti-inflammatory , anti-pyreticand anti-cancerous (both against carcinomas and forms of leukaemia). But it has not yet beenclarified whether its action is based only on an immune stimulating activity or it also has anapoptotic and pseudo-apoptotic activity. Parirubin A and Parirubin B are particulartropoloisoquinolic alkaloids: they are both effective against leukaemia in humans, but is has not yetbeen clarified whether their action is based only on an immune stimulating activity or whether it hasan apoptotic or pseudo-apoptotic basis.Marasdenia cundurangoIt was recommended in the past as a cure against gastric carcinomas. A group of Japaneseresearchers have found a certain cytostatic activity of its pure glycosydes (Condurangins) onEhrlich carcinomas and on carcinomas 180 ( 616,617 ). But other studies have not confirmed its neoplasticactivity ( 618 ). It is, however, effective in cases of gastric ulcers and gastro-duodenitis.Tribulis terrestrisIt is known as "Arbor sancta" for its ability to treat temperatures, hepatitis, and ulcers: it is immunestimulating, anti-bacterial, anti-viral, anti-helminthic, an insecticide, an insect repellent, anantiseptic, anti-inflammatory, a diuretic and an antipyretic. From this the following have beenisolated: Diosgenin, Gitogenin, Ruscogenin, Kempferol, Tribuloside, Terrestroside F, Campesterol,beta-Sitosterol, Stigmasterol, Neotigogenin.Momordica charantia (African watermelon)Alfa-Momorcharin, a glycoprotein taken from its seeds, inhibits the growth of tumoral lines.Furthermore, this molecule increases the tumor-killing effect of mice macrophages on mastocimalmurine cells (P815). It is also effective against leucemia cells. ( 639 ) The juice of its fruit has provedparticularly effective as an anti-oxidative and hypoglycemiant.215

Sida cordifolia (Bala)Bala strengthens the immune defenses, it has positive results, on the patient, in the case of leucemiaand sarcomas. It has also been experimented, in vitro, with success against nasopharynx carcinomas( 620 ); its anti-myotic, anti-bacterial, anti-viral and anti-helminthic action has also been verified. Itdoes, however, contain Ephedrine, a toxic substance, which is particularly dangerous for heartpatients or with hypertension. It should be administered only in doses which a doctor considers safefor the patient.Asparagus racemosusThe alcoholic extract from Asparagus racemosus has shown that is has an anti-tumor effect in vitro,against human skin carcinomas and nasopharynx carcinomas( 700 ).It is not yet clear whether it is based on immune stimulation or on apoptotic or pseudo-apoptoticinduction (752 ). It also inhibits the growth of Entamoeba histolytica.It must however be noted that it can cause a hyposensitive effect. The extract from the roots (antidiarrhea),on the other hand, causes an increase in cardiac range and frequency, even with lowdoses. Unfortunately, today in USA, this precious source of phytochemical molecules, which arejust as good as recent anti-cancer plants, are seriously threatened by asparagus-GMO (withtransgenic-virus too).Seeds from Linum usitatissimum (flax or linseed)contain ligands which seem to be effective against different tumors, and above all against breastcancer. Dosage, unless there are medical indications to the contrary: 1 teaspoon of seeds a day, andadd flax seed oil to salads or to soups and other dishes after cooking. NB :use fresh seeds.The young bark of Cinnamomum zeylancium (cinnamon, cinnamon from Sri Lanka and fromMadagascar) unless there are medical indications to the contrary, take it every day.The leaves and roots of Taraxacum officinalis (dandelions, chicory) unless there are medicalindications to the contrary, eat them every day, raw, in salads, so as not to lose their activeprinciples.The stalks with the flowers and the leaves of Thyme vulgaris (pepoline, garden thyme), unless thereare medical indications to the contrary, take it very day.The flower tops of Thymus serpillum (wild thyme, citron thyme and Erba soltorella): high dosescan cause nausea, vomiting bradycardia, asthenia, bradypnea and hypothermia (reversible if theplant therapy is suspended).The twigs with the leaves and the flower tops of Rosmarinus officinalis (rosemary): unless there aremedical indications to the contrary, take it every day.The flower stems of Crocus sativus (saffron) seem to have an anti-cancerous action.The seeds of Coriandum sativum (coriander, crane’s bill): the therapeutic value has not been noted(Apoptose is suspected), which is particularly serious because the plant is toxic (except for theseeds). In any case there can be side effects on the kidneys.216

A decoction of the peel of the roots of Berberis vulgaris (barberry): contains Berberin, which couldhave an immune stimulating activity( 1002 ); high doses have a serious effect on the heart; it has beenused in the cachexia from cancer; note: the same Berberin could be particularly effective againstamoebic dysentery and giardiasis; prepare a mixture of about 30 grams in 1 liter of water, and boilfor 10 minutes. Take at least 3 cupfuls a day, unless there are medical indications to the contrary.Curcuma longa (saffron from the Indies): unless there are medical indications to the contrary take itevery day.Sauces of Menta arvensis, rotundifolia, piperita, spicata (mint, peppermint and spearmint): unlessthere are medical indications to the contrary, take it every day; it is thought to have an apoptoticaction on some tumors. The immune stimulating action of the oil of Mentha piperita (peppermint)is well known, as for example in Russia against TBC ( 807 ).The leaves and flower tops of Origanum vulgare (oregano): unless there are medical indications tothe contrary, take it every day either as a decoction or an infusion.The berries of Capsicum annuum, fasciculatum and frutescens (chili peppers, red pepper, cayennepepper): high doses can cause gastro-intestinal and kidney inflammation. It should not be prescribedfor those who suffer from gastritis or ulcers.Ananas sativus or comosus (pineapple): as well as an enzymatic action of Bromelain (SEE chapter7), it could also have the ability to inhibit the growth of cancerous cells in vitro thanks to anotherenzyme ( 641 ): it has therefore been suggested to increase the intake of pineapple stalks to amaximum, provided they are biologically grown.The Crucifers, such as :Brassica oleracea and Brassica oleracea capitata (cabbage), Brassicaoleracea bullata (brussels sprouts), Brassica oleracea botrytis (cauliflower), Brassica oleraceaitalica (broccoli), Brassica rapa (turnip), Raphanus sativus parvus (radish), all contain particularanti-neo-plastic substances, in particular the isothyocyanates (which inhibit the development andgrowth of tumors), Indoles, Glucosynolates and Dithiolithones (anti-oxidants);( 809 ).It is a family of plants which cure many pathologies, not only tumors in man. For this family ofplants Valnet counted as many as 80 different pathologies, and in particular he advised eatingcentrifuged biologically grown cabbage. The use of cabbage leaves in cures is very interesting, andrecalls that of the leaves of Aloe arborescens,. Both the therapies of Gerson and Breuss used theseplants a lot. With regard to Brassicaceae, Pliny the Elder said that “… thanks to these plants theRomans managed without doctors for at least six centuries of war…”.Unfortunately, today, this precious source of phytochemical molecules, which are just as good asrecent anti-cancer plants such as Aloe arborescens, are seriously threatened by transgenic pollutionfrom GMO. SEE in PDF : Antony A. Miller: Accumulation of very-long-chain Fatty acids in membrane glycerolipidsis associated with dramatic alterations in plant morphology, The plant Cell, Vol. 11, pp. 1882-1902, 1998,www.plantcell.orgIn particular please note:The manipulation and genetic modification of slow-ripening cauliflowers ( 986 ).The manipulation and genetic modification of slow-ripening broccoliThe manipulation and genetic modification of virus-resistant lettucesThe manipulation and irreversible genetic modification of the very important oil from the seeds ofBrassicaceae ( 806 ).Dangerous( 968 ): GMO-Brassica rapa (turnip), GMO-Brassica oleracea botrytis (cauliflower).217

The herb decoction of Rene CaisseThe formula based on a decoction of herbs of Rene Caisse ( 520 ) is famous: the roots of Arctiumlappa (burdock), Rumex acetosa,(sorrel) the bark of Ulmus rubra (elm) and the roots of Rheumpalmatum (chinese rhubarb).The proportions of these ingredients are in a multiple of 4 ( 520 ). 1 part of the roots of Rheumpalmatum (chinese rhubarb) 4 parts Ulmus rubra(elm) 16 parts Rumex acetosa (sorrel)and 24 partsof the roots of Arctium lappa (burdock). According to the author, Ulmus rubra (elm) could besubstituted by Betula alba (birch).The preparation is as follows:1) Take 100 grams of these herbs and put them in 5 liters of water in a stainless steel pan whichholds at least 10 liters.2) Put a lid on the pan and bring it to the boil, simmer for 12 minutes.3) Turn off the gas and stir the mixture to make sure there are no herbs stuck to the inside ofthe pan.4) Put the lid back on and leave the mixture for at least 6 hours or overnight.5) Remove the lid and stir.6) Heat the mixture up, but do not boil it.7) Wait for the herbs to settle on the bottom of the pan and then pour the still warm liquid into4-5 liter bottles, preferably previously sterilized.8) Preserve the preparation in the fridge, in the dark in the same way as Aloe arborescens.The doses suggested are the following: 8 full soupspoons in a glass of warm water 3 times a day, onan empty stomach. If the immune response is induced, begin the maintenance treatment of 4 fullsoupspoons a day.Note: an empty stomach means 1 hour before meals, or 2 hours after meals.Renè Caisse’s formula was later improved by De Sylva (defined the Caisse Formula) adding threemore plants to the preparation ( 520 ): the bark of Xantoxilum fraxineum, the leaves of Plantago major(greater or rat tailed plantain) and the flowers of Trifolium rubeus (red trefoil): this would seemmore effective than that based on only 4 herbs.It must be prepared in small bottles and then pour a teaspoon into a cup, add boiling water and wait15 minutes, compared with 3 minutes for Camellia sinensis (green tea), then strain the liquid (orleave residue at the bottom), and drink it like a normal cup of tea.One small bottle will last from 15 days to two months, according to how much is consumed: theadvisable dose is a level teaspoon four times a day for serious tumors. During remission of theillness a level teaspoon twice a day is sufficient.A formula similar to Renè Caisse’s is Hoxsey’s formula:Arctium lappa, Glycyrrhiza glabra, Berberis vulgaris, Xanthoxilum fraxineuem, Trifolium rubeus,Alchimilla vulgaris, Larrea mexicana, Rhamnus sagrada o purshiana, KI (Potassium Iodure).Note: Glycyrrhiza glabra (liquorice) considerably lowers the production of hydrogen peroxide,superoxide and hydroxic radicals by the neutrophils (anti-inflammatory, anti-ulcergenic, antimicrobicand anti-oxidant effects); it is also able to inhibit the insurgence of skin tumors in animalsin experiments; a powerful stimulator of interferon secretion, denominated SNMC has beenidentified among its components. Finally, glycyrrizic acid and the 18a- and 18b- glycyrretinic acidshave been shown to have anti-mutagen properties.218

Rudolf Breuss’ FormulaRudolf Breuss’ formula is famous, above all, in German speaking countries: 300 grams of Betavulgaris cruenta (red beet), 100 gram of raw carrot which has been biologically grown (Daucuscarota), 100 grams of the tuber of meum mutellina (celery from monte, levistico) or Apiumgraveolens (wild celery), 30 grams of Cochlearia armoracia (radish), 100 grams of a decoction ofpotato peel (Solanum tuberosum) drunk cold; according to the German author it is necessary toavoid eating any other foods during the whole period of the cure (this is in contradiction to the otherherbal preparations which are the object of this chapter), all the components of his preparation mustbe drunk, there should be no solid residue: therefore the vegetables must be liquidized, and thenfiltered through a fine filter or a linen cloth. According to the German author it would be better touse a handful of raw potato peel, boiled in 2 cups of water for 4 minutes rather than using 100grams of whole potato. He also recommends the practice of salivating very well before swallowing:this has a well known medical value given the importance of the enzymes present in saliva indigestion.Note : Do not eat Apium graveolens (wild celery, sweet celery, marsh celery) if it is fresh.Formula of Salvia officinalis, Hypericum perforatum, Mentha piperita and Melissa officinalis:The preparation of Salvia officinalis (sage) is also well known: it is left in an infusion of boilingwater for no longer than 3 minutes (as for green tea), with 2-3 teaspoons in half a liter of boilingwater; when the 3 minutes are up, add Hypericum perforatum,(St. John’s wort) Mentha piperita(peppermint) and Melissa officinalis (lemon balm) and leave to infuse for a further 10 minutes. Stirthe mixture and then drink it, the dosage must be prescribed medically.From the leaves of Salvia officinalis the following have been isolated: Flavonoids, Fenols,oxytriterpenic acids, dyterpene, tannin, alpha and beta-Pinene, Canfene, beta-Myrcene, alpha-Terpin, Limonene (apoptosis in Leukaemia cells), Eucalyptol, gamma-Terpin, Lynalol etc.Apoptosis in epatocarcinoma and another cancer for caspase 3 ( 708,1015,1116 ).The following have been isolated from Melissa officinalis: essences, alcohols, fenolic acids,triperpin, flavonoids, tannin, vitamins B1 and B2, and mineral salts. It also has an interesting antihormoneaction (inhibition of TSH); the induction of selective apoptosis in glyoma cells is alsosuspected. According to recent studies Hypericum perforatum, would appear to induce selectiveapoptosis in human T Lymph node cells, and Eritro-leukaemiaMaria Treban’s tisaneEquisetum arvense (common horsetail), Calendula officinalis (pot marigold), Achillea millefoliumor filipendulina, Urtica dioica (perennial nettle), Rumex acetosa (sorrel).A tisane of Melissa monarda (bergamot) and Melissa officinalis (lemon balm):unless there are medical indications to the contrary, leave half a tablespoon in boiling water for 10minutes. It would appear to be effective on glyomas.A mixed infusion of Calendula officinalis or silvestris (pot marigold) and Achillea millefolium orfilipendulina with Swedish Bitters.219

An infusion of Alchimilla alpina and Alchimilla vulgaris with Urtica dioica (perennial nettle) andLamium album (white nettles): unless there are medical indications to the contrary, leave 1 mixedtablespoon in boiling water for 10 minutes.A preparation of Pimpinella major (salad burnet) gargled (it is thought to act on tumors in the oralcavity): unless there are medical indications to the contrary, leave 1 tablespoon to infuse in boilingwater for 3 minutes. After gargling, swallow the mixture.Chopped up Acorus calamus (sweet flag) it would appear to act on gastric carcinomas; it is a coldtisane (chop the herb up in cold water).A tisane of Salvia officinalis (sage) (about 1 liter), mixed with the flowers of Equisetum arvense(common horsetail) (boiled for 10 minutes) and/or the flowers of Trigonella foenum graecum (onlyfor infusions): they would appear to act on leukaemia lymphomas and tumors in the pancreas. It is,however, certain that Equisetum arvense stimulates hemotopoiesis and it acts almost as effectivelyas shark cartilage on the degenerative processes of the cartilages and the bones (arthritis andarthrosis); perhaps it could induce an angiogenic check on newly formed vessels similar to thatalready demonstrated by shark cartilage (SEE chapter 13).A tisane of the flowers of Epilobium parviflorum, would appear to act on tumors of the bladder, theprostate gland and perhaps the testicles.Hot compresses of the leaves of Plantago major (greater or rat tailed plantain) are well known formelanomas (but, preferably, according to the author, the alternative use of Aloe arborescens both asa compress and above all for oral administration, given the apoptosis action induced by Emodin).Euspongia officinalis (sea sponge) is very particular: it is picked in the Mediterranean, the Red Seaand the Atlantic; it would appear to be effective against lymphomas and tumors in the thyroid;however it contains iodine, so it cannot be given to patients who are at risk from thyroid toxicosis orin patients waiting to undergo metabolic radiation with Iodine 131.Infuse a teaspoon of the flower tops of Cnicus benedictus (blessed thistle) in a cup of boiling waterfor 10 minutes. The dosage to be based on a medical opinion.A decoction of the roots (20 grams) of Carlina acaulis (stemless curline thistle) in a liter of water.Stellaria media (common chickweed) : It should be cooked in a similar way to Spinacia oleracea(spinach).A decoction of the roots (30 grams) of Polygonum bistorta in 1 liter of water. Bring it to the boiland simmer for 5 minutes. The dosage to be based on a medical opinion.5–15 grams of the leaves of Stachys officinalis (wood betony) in half a liter of boiling water (aninfusion).Infuse 20 grams of Alliaria matronalis (the whole plant) in 1 liter of boiling water.Infuse the leaves of Hesperis matronalis (sweet rocket) in 1 liter of boiling water for 10 minutes.Infuse 10–12 grams of Agrimonia eupatoria (agrimony)220

A decoction of the roots of Enula campana; from 10 - 20 grams in a liter of water.For jaundice (cancer liver): a decoction of Ononis repens with an infusion of the seeds ofFoeniculum vulgare (sweet fennel) unless there are medical indications to the contrary: 20 grams ofthe roots of Ononis repens; 5 grams of the seeds of Foeniculum vulgare; 1 liter of water. Boil theroots of Ononis repens until the water is reduced to ¼ of the original quantity (250 milliliters); thenput the seeds of Foeniculum vulgare to infuse in boiling water for 5 minutes. Strain everything andgive one cup to drink every 2-3 hours.Infuse 1 teaspoon of the fresh flowers of Calendula officinalis (pot marigold) in a cup of boilingwater for 10 minutes, unless there are medical indications to the contrary.Steep 15 grams of finely chopped root of Marasdenia condurango in 300 milliliters of water. Boilto reduce the water to 200 milliliters. Sieve it while hot, pressing it. Take 2-3 tablespoons beforemeals, unless there are medical indications to the contrary.Infusion of the roots of Polygonum aviculare (knotgrass): one dessert-spoonful to a cup of water.Boil for 2 minutes, infuse for 20 minutes. The dosage is to be based on a medical opinion.A decoction done in two stages of Triticum repens also adding the roots of Rubia tinctorium (unlessthere are medical indications to the contrary) and the roots of Glycirrhiza glabra (liquorice). Boil 30grams of Triticum repens for one minute. Throw away the water. Crush the Triticum repens andboil it again in 1,200 milliliters of water, until the liquid has reduced to one liter. Add 60 grams ofthe root of Glycirrhiza glabra and 15 grams of the roots of Rubia tinctorium (madder). Leave theinfusion for 20 minutes. The dosage is to be based on a medical opinion.Drosera rotundifolia (sundew): use the whole plant. 15 grams to 1 liter of water (an infusion).Diplotaxis tenufolia (perennial wall rocket): the flour made from its seeds can substitute Senapsisalba (mustard).Infuse 60 grams of Marchantia polymorpha (the dried plant), chopped up in one liter of water.Take 2 glassfuls a day unless there are medical indications to the contrary.The stems or the whole plant of Equisetum arvense (common horsetail). A decoction of the wholefresh plant: 50-100 grams/one liter of water, boil for 30 minutes.A decoction of the whole dried plant: 10-20 grams/one liter of water, boil for 30 minutes.Infusion of Tanacetum balsamita (tansy) or Chrysanthemum balsamita: 1 dessertspoonful to onecup for 10 minutes, unless there are medical indications to the contrary. Drink after meals.Infuse 60 grams of the roots of Geum urbanum (wood avens) or Geum rivale in one liter of waterfor 10 minutes. Drink half liter a day, unless there are medical indications to the contrary.Note: Geum urbanum (wood avens) is toxic.Steep in one liter of Malus communis vinegar: 30 grams of Geum urbanum, 10 grams of Salviaofficinalis (sage), 10 grams of Menta piperita (peppermint) and 10 grams of Ruta graveolens (rue).Leave it to steep for 24 hours. Filter it. Take a sip 4 to 6 times a day, unless there are medicalindications to the contrary.Note: Geum urbanum (wood avens) and Ruta graveolens (rue) are toxic.221

Infuse 15 grams of Lippia citriodora in one liter of water (similar to Melissa officinalis [lemonBalm]).A decoction of Erica cinerea or Cullana vulgaris (heather): a handful of the flower tops in a liter ofwater. Boil for 3 minutes and keep it infused for 10 minutes. Drink it in 2 hours, unless there aremedical indications to the contrary.Fluid extract: 60 drops of Erica cinerea + 50 drops of Solidago virgaurea + one soupspoon of: thesoft part of the stems of Zea mais (3 grams); the fluid extract of Equisetum arvensis (commonhorsetail) (10 grams); the syrup of Rubus idaeus (100 grams), 300 milliliters of water.A decoction of a handful of the roots of Eryngium campestre (sea holly or eryngo) in one liter ofwater. Boil for 5 minutes. Drink in 2 days.A decoction of a handful of the roots of Eryngium maritimum in one liter of water. Boil for 5minutes.Infuse Sysymbrium officinalis (*) a dessertspoonful of the whole fresh plant for 10 minutes in a cup.Take 3-4 cups a day; a soupspoon every 2 hours of:1) the fluid extract of Primula officinalis (50 drops)2) a mixture of the syrup of Sysymbrium officinalis (SEE below)3) The principle parts (roots, rhizome ,bark infused in water) of Tilia cordata, europaea,platyphilla or vulgaris :200 ml.(*) Note: this plant was mentioned by Castore Durante in his cure for “Cancaro”, on page 174a, ofhis book "Herbario novo", in 1617.A mixture of the syrup of Sysymbrium officinalis (*)A handful of the leaves and a handful of the flowers of Sysymbrium officinalis; 10 grams ofGlycirrhiza glabra (liquorice), one liter of water. Boil and reduce the liquid by 1/3. Strain. Add 200grams of Honey. Simmer in a bain-marie until it is like a syrup. Take a few soupspoons during theday.(*) Note: this plant was mentioned by Castore Durante in his cure for “Cancaro”. on page 174a, of his book "Herbarionovo", in 1617.For Leukaemia:20 grams of Veronica officinalis25 grams of Filipendula ulmaria aut Spiraea ulmaria25 grams of Galium aparine30 grams of Sambucus nigra (shoots)25 grams of Achillea millefolium15 grams of Hypericum perforatum20 grams of Artemisia abrotanum15 grams of Urtica dioica30 grams of Taraxacum officinalis30 grams of Calendula officinalisAnother plants: Aloe arborescens, Essiac’s formula, Brazil plants as: Simaruba amara, Physalisangulata, Scoparia dulcis, Petiveria alliacea, Schinus molle, Uncaria tomentosaNOTE: For another tumour, famous Brazil plant is Annona muricata; Its sold by a private companyalong with other mediacal herbs (Mormodica charantia, Maytenus illicifolia, Physalis angulata,Scoparia dulcis, Guazuma ulmifolia, Uncaria tomentosa).222

Chap. 9.e.:Anti-cancerous plants or similar plants with immune stimulatingproperties, mentioned in Herbario NovoIn his book Herbario Novo published in 1617, Castore Durante mentions 825 plants known inEurope and in both the East and West Indies, and the secret remedies obtainable from these plants(the admirable virtues of the herbs ....... discovering rare secrets and particular remedies to curethe most difficult illnesses of the human body ......). In particular he describes 11 plants which wereconsidered even then as cures against "Cancaro", which was how Cancer was called then, and Aloewas mentioned for its curative qualities against "malignant ulcers":Page 34D: “Antora” or “Zedoaria” (probably Curcuma zedoaria) (turmeric).Page 146D: “Consolida media bugula”, probably Ajuga reptans (well known in the past as animmune stimulant for TBC) or Ajuga piramidalis (Bugle).Page 162B: The roots of “Dragontea maggiore”: probably Artemisia dracumculusPage 170D: ”Epithimum” : probably Cuscuta epithimumPage 174A: Erysimum officinale: in the past it was known as an immune-stimulant for TBC.Page 188B: Filipendula ulmaria or Spiraea ulmariaPage 224A: “Heliotropium minus” : perhaps this is Heliotropium europaeumPage 228BD: “Nicotiana” (old Italian), “Tobacco” (old Spanish): probably this is Nicotiana alata(Tobacco flower) or perhaps Nicotiana tabacum (Tobacco plant). They are considered poisonousnowadaysPage 324BD: Urtica dioica (perennial nettle) (doubtful for Urtica urens (annual nettle), Lamiumalbum or Acalypha indica).Page 325A: Hordeum volgare (barley).Page 408D: a decoction of the roots of Smilax aspersa, or Smilax sarsaparilla or Smilax utilis(doubtful for Smilax china or Hemisdesmus indicus).A particular note is dedicated to Aloe, on page 17D of "Herbario Novo", where its ability to curepatients with malignant tumors is recognized.On page 18 on the other hand, another Aloe is reported called "Aloe Americana", but no propertiesagainst malignant tumors or similar are attributed to this plant. Looking carefully at the twosketches of the two Aloe plants, the author would maintain that the first Aloe, on page 17,corresponds to Aloe ferox (which has therapeutic qualities similar in many ways to Aloearborescens); and the second Aloe (“Aloe Americana”), corresponds to Aloe vera, which isgenerally considered to have 3 times less the concentration of active principles compared to Aloeferox and Aloe aborescens.Many other plants are mentioned for the cure of "tumors" (perhaps not always malignant tumors) onthe following pages:2C: Artemisia abrotanum : southern wood31A: the roots of Angelica arcangelica (angelica) or silvestris. (wild angelica).67A: the leaves of “Bellide maggiore“: perhaps this is Leucanthemum vulgare or Bellis major(daisy, spring flowers, primroses):71A; Beta alba (white chard): probably it is really Beta alba var.cicla.81D: the flowers of Buphthalmum oculus buvus (oxeye, bull's eye). Probably it is the well knownBuphthalmum salicifolium (bull's eye, asteroid).223

100B: Cicer arietinum (chickpea) for tumors of the liver: Chickpea flour cooked in Endive water.107A: the leaves of Chervil (“Cerfolium”) this is probably Anthriscus cerefolium, similar inappearance to Apium petroselinum (Note from the author : both these plants are known today ascures for various pathologies, but they are, unfortunately, similar in aspect to Aethusa cynapium(garden hemlock) and to Cicuta virosa (poisonous hemlock); however, the latter can bedistinguished from Parsley or Chervil by pressing 3 or 4 leaves between the fingers: its nauseatingsmell is characteristic).126D: Cicorium intybus (chicory, radicchio).129A: Cuminum cyminum (roman cumin), according to Durante it should be taken with pinkHoney.131C: “Mercorella bastarda”. It is not clear whether it refers to Mercurialis annua of theEuphorbiaceae family, and therefore toxic or potentially toxic.137D: Cytisus laburnum or Cytisus scoparius (broom); they are toxic.147D: “Sperone di Cavaliere”(This is Delphinium consolida (royal comfrey or knight's spur) knownSolanaceae, potentially toxic, it is still being evaluated by the author.169B: the white foliage of Chicorium endivia latifolium (endive).172A: the flowers and seeds of Erica vulgaris (heather)174D: “Orobis”, “Ervum”, probably Ervum ervilia.181B: Vicia faba (broadbean). Durante maintained that they were useful against "tumors" of thetesticles.207B: the berries of Juniperus communis (juniper), for tumors of the neck and chest (they arecurrently considered slightly toxic).208C: the flowers of Coronilla emerus, Cytisus scoparius, Sarothamnus scoparius, Spartiumscoparium, juniceum (different types of juniper), they are toxic.209A: “Gingidium “: Durante said that "....... it is not the common chervil, even if it looks like it". Itis probably Daucus gingidium.231ABC: the green leaves of Hyoscyamus albus referred as effective against "tumors" of the lungs,the spleen and the testicles. This plant is still being studied for its possible toxic effect by the author.238B: Gnaphalium polycephalum or supinum or vira vira.239C: Iris sylvestris major.248B: the leaves of Laurus nobilis (laurel).262A: the seeds of Linum usitatissimum (flax): Durante said that "... flax seeds remove all types of"tumor"...", this has also been reported in Chinese and Indian texts; in the Gerson Therapy the oilof seeds of Linum usitatissimum (flax) is important for Omega-3 ( 749 ).263A: Pseudolinum (false flax). Durante referred to it as a cure against ".. "tumors" of thenerves...."307D: Nasturtium officinalis (nasturtium).330D: Panaces ascletanus : Durante maintained it was an effective cure against “malignant tumors”and “little tumors”; perhaps Heracleum sphondylium : Panace, Italian ginseng.340C: the roots of “Pentaphillo”. It is probably the well known Potentilla alba (cinquefoil) or atleast from the same family. It is currently being evaluated.390B: the roots of Rheum officinale or sinense or palmatum (rhubarb): it is also used in ReneCaissè’s formula (the famous decoction of Canadian herbs).407C: The juice of the bark or the leaves of greek willow or willow. It is probably Salix babylonica.431A: Sesamoides parvum.455A: Thapsia garganica.(Thapsia)463A: Tribulus acquaticus.470CD: Verbena officinalis (verbena). Durante maintained it was effective against “tumors” of thespleen, the testicles and the head.471C: Veronica officinalis (veronica). Durante maintained that it was effective against “tumors” ofthe head.224

485C: “Vulvaria Garosmus “: probably Vulvaria species.487A: “ Xiris “: Iris foetisissima489C: Cucurbita maxima (pumpkin).Conclusions to paragraph 9.a, 9.b, 9.c, 9d, 9e:As with Aloe arborescens, these plants are also the cause of particular phenomena in the patient,which can probably be traced back to an immunitary activation, highlighted by the followingsymptoms and signs which can be integrated with blood tests and instrumental tests:1. Nausea, vomiting, loss of appetite with intestinal and gastric pains, probably because of theactivity of the gastro-enteric lymph nodes.2. Possible transitory hyper-calcemia caused by an increase in IL-1 and TNF.3. A transitory increase in the tumoral mass, because of lymphocyte infiltration and subsequentphlogosis.4. A temperature (activation of the Immune Cascade), if there is an extended tumor.5. High levels of uric acid in the blood, possible onset of kidney damage.6. Ultrasonography: increase of lymph nodes (REACTIVES lymph nodes)225

Chap. 9.f.:Adjuvant immuno-therapy: Phyto medicines with an anti-stromalaction on connective cancer tissue…”Pancreatic proteolytic enzymes are the body’s main defenseagainst cancer and would be useful as a cancer treatment…”British Medical Journal, 1906Taking into account current literature, it must be pointed out that it is difficult for the white bloodcells to penetrate inside the neoplastic mass because of the high pressure of the interstitial fluid (H-IFP, see: Jain R.K.: Barrier to Drug Delivery in Solid Tumors, Scientific American, Science, July, 1994), andbecause of phenomena, which are not yet clear, of slight deformability of the LAK lymphocyte cellmembrane ( 391 ).This cancer barrier may, however, be vulnerable to particular agents such as pancreas enzymes andto other different enzymes contained in Aloe arborescens.What is more, the barrier could be vulnerable to Bromelain (a proteolytic enzyme found in thestalks of Ananas sativus or Ananas comosus, also found in the blood of patients after they had eatena good quantity of this fruit). It could also be vulnerable to Papain, an enzyme which is similar toBromelain, but contained in the leaves and the fruit of Carica papaya.A similar enzyme to Bromelain and papain also exists in Morinda citrifolia, in concentrations about800 times higher than in the stalks of Ananas sativus or comosus. This enzymatic similarity consistsof a co-enzymatic component (prosthetic group), that is, of an alkaloid (Xeronina) of which the presynthesiscomponents (Proxeronina and Proxeronasi) are also found in large amounts in the fruititself.Other proteolytic enzymes can be found in the roots of ginger (Zingiber officinalis), among which isZingibaina, which has proved more effective than papain itself.In Africa the wood and the dried and pulverized bark of Okoubaka aubrevillei is currently beingstudied because it could possibly have a pancreatic or similar enzyme action.Finally we must also mention Eichornia crassipes (water hyacincth), with enzymes which are notyet sufficiently known but nonetheless similar to those mentioned above.There are many different herbal preparations on the market derived both from these and otherplants.In Gerson’s therapy ample use is made of similar pancreatic enzymes.According to the author, the possible use of these enzymes even for injections into the cancer itself,similar to those of Papain which have been used for hernias of the disk, should be evaluated.226

Note 1: some clinical cases of oncology therapy obtained by using extracts of corionic vessels, forexample those of Gavollo ( 141,147 ), have been reported in medical literature. This fact could lead oneto presuppose an immune stimulating action directed against the connective stoma of the tumor andpossible, therefore, as an immune-stimulating curative technique.Analogous to this form of anti-neoplastic activity, based on the activation of lysis phenomena of theextra-cell matrix of the cancer connective, probably on an immune basis, an anti-cancer technique,discovered in the past by the Italian doctor Armando Gambetti, should be researched. UnfortunatelyDr.Gambetti died in the 70s without being able to continue his important work.227

Chapter 9.g: The HOXSEY TherapyFrom INTERNET: Herbal Therapies for Cancer, by Vivekan Don Flint and Michael Lerner, Research Assistance:Melanie Smith, October 1997.(NON reported in Italian version of commercial Book “Diventa Medico di te stesso !”)Like the story of Rene Caisse and Essiac, Harry Hoxsey has assumed for some a stature larger than life, and the story ofthe therapy that bears his name the quality of legend.In 1919, at the age of 18, Hoxsey became involved in the mission passed down through his family from his greatgrandfather,John Hoxsey. As the story goes, John Hoxsey, a veterinarian, observed a horse with cancer instinctivelyeating certain herbs that grew in the pasture that was subsequently cured. Hoxsey gathered these herbs and successfullytreated other animals with cancer. The formulas he used were passed on to his descendants who used them to treatcancer in humans, as well ( 1500 ).Harry Hoxsey viewed cancer as a systemic disease, but did not claim to know its cause; he called himself an"empiricist", saying his treatment was based on experience and practice:We believe that the organism's attempt to adapt itself to the new and abnormal environment produced by the chemicalimbalance causes certain changes (mutations) in newly born cells of the body. The mutated cells differ radically inappearance and function from their parent cells. Eventually a viciously competent cell evolves which finds the newenvironment eminently suitable to survival and rapid self-reproduction. These cells are what is known as cancer.It follows that if the constitution if body fluids can be normalized and the original chemical balance in the bodyrestored, the environment again will become unfavorable for the survival and reproduction of these cells, they willcease to multiply and eventually they will die. Then if vital organs have not been too seriously damaged by themalignancy (or by surgery or irradiation) the entire organism will recover normal health ( 1501 )The Hoxsey Clinic was founded in Dallas, Texas, in 1924 and by the 1950s was one of the largest private medicalfacilities in the world, with branches in 17 states. Though initially very successful in terms of drawing patients--orperhaps because of this fact--the clinic became a target of organized medical groups. Hoxsey spent a good deal of histime in court defending himself against charges of practicing medicine without a license and using unapprovedtherapies, though none of his patients ever initiated legal proceedings against him ( 1502 ).Hoxsey fit the stereotype of a quack--a former coal miner and Texas oilman, he was initially reluctant to disclose hisformula and was a flamboyant character who openly taunted the medical establishment.Hoxsey alleges in his autobiography, You Don't Have to Die, that Malcolm Harris, M.D., Chicago surgeon and futurepresident of the American Medical Association (AMA), offered to buy his formula after observing its successful usewith a patient. According to Hoxsey, he would have received 10 percent of the profits, but only after 10 years. TheAMA would set the fees and keep all of the profits for the first nine years. Hoxsey said he refused the offer ( 1503 ).As part of the ongoing battle between Hoxsey and the AMA and FDA, Morris Fishbein, editor of the Journal of theAmerican Medical Association, published an assault on Hoxsey entitled "Blood Money" in the American Weekly in1947 in which he labelled Hoxsey a "charlatan." Hoxsey sued for libel and won. Though the award was only twodollars, it was nonetheless a stunning victory for Hoxsey. Fifty of his patients testified on his behalf, and Fishbein wasforced to admit during testimony that he had failed anatomy in medical school and had never treated a patient during hisentire career. He also admitted in court that Hoxsey's pastes had actually resulted in some cures for external cancers.Fishbein and the AMA were now on the defensive and he was soon forced to resign his position ( 1504 ).According to Hoxsey's autobiography in 1954 an independent team of ten physicians from around the United Statesvisited the Dallas clinic for a two-day inspection, during which they interviewed patients and reviewed medical records.Hoxsey claimed a signed report stated that the clinic was:...successfully treating pathologically proven cases of cancer, both internal and external, without the use of surgery,radium or x-ray.Accepting the standard yardstick of cases that have remained symptom free in excess of five to six years after treatment,established by medical authorities, we have seen sufficient cases to warrant such a conclusion...228

We as a Committee feel that the Hoxsey treatment is superior to such conventional methods of treatment as x-ray,radium, and surgery. We are willing to assist this Clinic in any way possible in bringing this treatment to the Americanpublic. We are willing to use it in our office, in our practice on our own patients when, at our discretion, it is deemednecessary ( 1505 ).Another team assembled by the Canadian government visited the clinic in 1957 from the University of British Columbiain Vancouver. They concluded that the Hoxsey medications "are of no value in the treatment of internal cancer and theexternal treatments used have no place in modern cancer therapy"( 1506 ).By the late l950s, Hoxsey was pressured out of business by FDA actions banning the interstate distribution of thetreatments and by posting warnings in 46,000 post offices nationwide. Mildred Nelson, his chief nurse, attempted tokeep the clinic going in other locations, but was encouraged by Hoxsey to move the operation to Mexico. Nelson stillruns the Bio-Medical Center in Tijuana today.Hoxsey employed one internal formula and three external remedies for cancers on or near the surface of the skin.Hoxsey believed the "yellow powder" to be highly selective for cancer tissue, leaving normal cells undamaged.According to Hoxsey, the yellow powder consisted of arsenic sulfide, talc, sulfur and what Hoxsey called a "yellowprecipitate." The "red paste" (antimony trisulfide, zinc chloride and bloodroot) and the "clear liquid" (trichloroaceticacid) were not selective. Vaseline or zinc oxide applied around the area protected normal tissues from the corrosiveactions of the latter ( 1507 ).Speaking about the external remedy used for skin cancers, Hoxsey said:In practice we have found that a small amount of our compounds, when placed on a large cancerous mass, cause achain reaction which extends an inch or two beyond the point of application. The mass dries, separates from normal,healthy tissue and falls out ( 1508 ).Interestingly, the ingredients in the red paste were used by Frederic Mohs, M.D., of the University of WisconsinMedical School in the 1930s and 1940s to treat non-melanoma skin cancers. Mohs' technique employed the paste andserial microscopic examination of excised tissues. The paste was applied and left in place for 24 hours, during whichtime the patient was given medication for pain. After the tissue had been killed and fixed, a layer approximately fivemillimeters thick could be excised with a scalpel and examined with no pain or bleeding. Several successiveapplications, excisions and examinations were performed until the tumour was excised.Mohs reported a 99 percent cure rate for all basal cell carcinomas he treated using this method. In a 1948 paper, Mohscontrasted his method with that of unconventional practitioners who did not used the fixative with the microscopiccontrol of excision, which he considered unreliable and excessively mutilating ( 1509 ).In the 1950s, Mohs abandoned the use of the fixative paste altogether in favor of surgical excision of fresh tissuespecimens, a method used today for some types of skin cancer ( 1510 ).Among other uses, bloodroot, one of the constituents of the red paste, has been employed in the United States as anexpectorant, an antiseptic, a cathartic and an emetic. Externally, it has been used traditionally for skin fungus and cancer( 1511 ).Walters reports that the rootstock of bloodroot (Sanguinaria canadensis) contains Sanguinarine, an alkaloid withpowerful anti-tumour properties, and that Native Americans living along the shores of Lake Superior used the red sap totreat cancer ( 1512 ). Drawing upon this lore, Dr. J. W. Fell working at the Middlesex Hospital in London in the 1850sreportedly treated cancer using a paste composed of bloodroot, zinc chloride, flour and water ( 1513 ).In his autobiography, Hoxsey lists the ingredients in his internal treatment as Cascara (Rhamnus purshiana) andPotassium Iodide, to which one or more of the following herbs were added depending upon the patient's condition,location of the cancer and previous treatment: burdock root (Arctium lappa), pokeroot (Phytolacca americana),barberry or berberis root (Berberis vulgaris), buckthorn bark (Rhamnus frangula), stillingia root (Stillingia sylvatica),prickly ash bark (Zanthoxylum americanum), licorice (Glycyrrhiza glabra), red clover (Trifolium pratense), andAromatic USP 14 (artificial flavor) ( 1514 ).According to the OAM, the presence of all these ingredients (with the exception of the flavoring) was confirmed in ananalysis by the Hipple Institute, though the volatility of some components means they might only be present in a freshstate and not in the final form ( 1515 ). According to the OTA report, the last two ingredients--red clover and flavoring--are not mentioned in Mildred Nelson's list of ingredients currently offered ( 1516 ).229

Many of the constituent herbs have long been used in various folk traditions as cancer treatments and others areconsidered to be cathartic or cleansing. According to James Duke:I should like to propose that there do exist bioactive compounds in that concoction that has been called "Hoxsey'sHoax." I am not here to support nor to refute the Hoxsey herbs, just to note the activity of compounds therein. PoorHoxsey was haunted by the Health, Education and Welfare Department (HEW) of his day, whose claims were probablyno closer to the truth than Hoxsey's. HEW stated back then, "Cancer can be cured only though surgery or radiation."That was before the marvels of phytochemicals like Vincristine and Vinblastine from the Madagascar periwinkle forleukaemia, and Etoposide for bronchial and testicular cancer from Mayapple root had been derived from the herbalpotpourri...Before he retired, Jonathan Hatwell of the National Cancer Institute published "Plants Used Against Cancer"...All tenof the Hoxsey herbs were generously cited in the folklore. Hoxsey certainly was not alone in suggesting anti-canceractivity for these plants.Duke also notes that all of these herbs are listed in the 28th Dispensatory of the United States, with the recommededdosages two to three times higher than the dosages in the Hoxsey formula ( 1517 ).Cascara (Rhamnus purshiana)The OAM reports that in American folklore cascara used both as cathartic and as a cancer remedy ( 1518 ). According toBoik, both Cascara and another constituent of the Hoxsey therapy, buckthorn, contain Rhein and Emodin, promisinganticancer agents which have been described previously.A 1952 study cited in the OTA report on Unconventional Cancer Treatments found no anticancer activity in apowdered suspension of cascara in the Sarcoma 37 system ( 1510,1519 ). The same report describes a series of 16 tests bythe NCI which found no antitumor activity with Cascara (1520).Cascara is a cathartic and an overdose can lead to severe diarrhea and dehydration ( 1521 )Burdock root (Arctium lappa)Burdock root is also one of the constituent herbs in the Essiac formula, and research on its anticancer properties arediscussed in that section.Pokeroot (Phytolacca americana)Among other traditional uses cited by the OAM report, pokeroot is listed as an American folk remedy for cancer ( 1521 ).One published study reported no significant antitumor activity with pokeroot in three animal test systems (Erlichascites, leukaemia SN36 and sarcoma 180) ( 1522 ). The OTA also cites 43 tests for anti-tumour activity carried out by theNCI, one of which was positive, but which was withdrawn because of problems with its validity ( 1510 ).In other studies, pokeroot has demonstrated the capacity to stimulate a mitogenic (immune) response{249} and tostimulate interleukin production ( 1527 ). One component of pokeroot has been shown to have the ability to induce theproliferation and differentiation of lymphocytes in the blood ( 1510, 1528 ). The OTA report suggests this property might berelevant to an immunologic response to cancer which might not be picked up as positive activity in animal tumourmodels ( 1510 ).Research in China on a related species, Phytolacca acinosa, demonstrated that polysaccharides derived from the plantsignificantly enhanced the ability of macrophages to kill sarcoma cells and malignant fibroblasts. Macrophagesincubated with pokeroot derivatives produced significantly more tumour necrosis factor (TNF) and interleukin-1 (IL-1).A substance derived from pokeroot, PEP-1, was as effective as Bacillus Calmette Guerin (BCG) at stimulating TNFproduction and better than BCG in its effect on IL-1 production ( 1529 ).Pokeroot has been liked to poisonings, including some fatal episodes, in both children and adults ( 1530 ).Barberry (Berberis vulgaris)One of the most interesting and most researched constituents of the Hoxsey therapy is barberry, also known as berberis,jaundice berry, woodsour, sowberry, pepperidge bush and sour spine. Jonathan Hartwell lists traditional uses ofbarberry for cancer in Arabic medicine and against nasal polyps in traditional Chinese medicine ( 1521 ).230

The OTA report Unconventional Cancer Treatments cites one test of barberry in which no anti-tumour activity wasdemonstrated ( 1510 ). However, in 1976, researchers reported on the anticancer properties of a substance isolated frombarberry, lycobetaine ( 1531 ). And another derivative of barberry, Berberine, has been the subject of research as anantibacterial, anti-malarial and fever-reducing drug. Boik describes the research on Berberine in some detail, also listingit as an anti-tumour compound of particular interest. According to Boik, Berberine produces an anticancer effect,though the mechanism by which it works is unclear ( 1532 ).Berberine inhibits the uptake of oxygen by tumor cells ( 1533 ) and induces differentiation in human teratocarcinoma cellsin vitro. In this study, Berberine was a more powerful differentiating agent then vitamin A, but only at concentrationsthat might be difficult to achieve without significant toxicity ( 1534 ).In other studies, Berberine at a much lower concentration inhibited the growth of a human hepatoma cell line ( 1535 ) andin Erlich and NK/Ly lymphoma cells lines ( 1533,1536 ). Berberine also exhibited marked cytotoxicity at low concentrationsin a human HeLa cell line ( 1537 ).Some in vivo studies of Berberine's anti-tumour activity have also been conducted. A single intraperitoneal dose ofBerberine to rats bearing 9L brain tumours resulted in an 81 percent cell kill after 24 hours ( 1539 ). However, in anotherstudy, Berberine did not cross the blood-brain barrier in rats when injected intravenously. In this study, intraperitonealadministration of Berberine three times a day did increase the lifespan of rats bearing P338 lymphocytic leukaemia by12 percent, but did not increase the lifespan when the P338 cells were injected intracerebrally ( 1540 ).In another study, intraperitoneal Berberine did not inhibit Erlich ascites tumour growth in mice ( 1541 ).Boik points out that the anti-tumour effects of Berberine may be related in part to its immune enhancing effects, citing astudy by Kumazawa in which Berberine markedly activated macrophages against EL4 leukemic cells in vitro ( 1541 ).Based on the available evidence, Boik does not believe that Berberine is likely on its own to produce a significant antitumoureffect. However, he does conclude that it might be useful in combination with other agents such as vitamin Aand DMSO that might reinforce its differentiating effects, an approach that has not been studied clinically ( 1533 ).Whether or not the other herbal constituents of the Hoxsey therapy might serve this purpose is at this point an openquestion.Boik also takes note of the possibility that the anti-bacterial effects of Berberine may alter gut flora when taken orally( 1542 ).Buckthorn bark (Rhamnus frangula)Hartwell reports that buckthorn has been used as a folk remedy for cancer in England and the United States ( 1521 ).Buckthorn bark has yielded Emodin, the anticancer activity of which has been described previously. However, in threeNCI tests in animal systems buckthorn bark failed to demonstrate any anti-tumour activity ( 1510 ).Stillingia root (Stillingia sylvatica)Stillingia root is a cathartic and emetic in large doses and has been used as a folk remedy for cancer in the United States( 1521 ). Very few studies have been done on the properties of Stillingia sylvatica and the NCI has no records of screeningthe herb for anticancer activity ( 1510 ).Stillingia root is a toxic irritant, causing swelling and inflammation of the skin and mucous membranes ( 1521 ).Prickly ash bark (Zanthoxylum americanum)Hartwell reports this and related species have been employed as folk remedies for cancer in the state of Georgia, theAntilles, China and the West Indies ( 1521 ).231

Licorice (Glycyrrhiza glabra)This is the commercially-available licorice long employed as a flavoring and, according to Hartwell, as a remedy forvarious cancers in Indian, Arabic, Chinese and Japanese traditional medicines ( 1543 ). Licorice is a component of Juzen-Taiho-To, an intriguing herbal therapy for cancer from the tradition of Kampo, the Japanese version of traditionalChinese medicine ( 1544 ).The NCI has tested licorice 19 times, with one sample showing activity that was not considered significant. Anotherstudy showed licorice to be inactive in the Sarcoma 37 test system ( 1545 ).Substances demonstrating anticancer activity that have been isolated from licorice include Benzaldehyde (also found inburdock, described previously), as well as Fenchone, Glycyrrhizin, Indole, Quercetin and beta-Sitosterol ( 1510 ).Red clover (Trifolium pratense)Hartwell reports 22 references to the use of red clover flowers or leaves for cancer, most often breast cancer, in severalEastern states as well as Europe, the Ukraine, Leipzig and Australia. Analyses of the leaves of red clover have revealedthe presence of estrogens, which might account for their use, particularly for breast cancer ( 1521 ).Boik notes that clovers contain Genistein, a promising anticancer agent that inhibits platelet aggregation, inducesapoptosis, inhibits angiogenesis, reduces the bioavailability of sex hormones, induces differentiation in cancer cells andis relatively non-toxic ( 1546, 1547, 1548 ).The NCI tested red clover 94 times, with one test showing activity that was not considered significant ( 1510 ). Red cloveralso demonstrated no activity in the P388 system ( 1549 ).Potassium IodideThe British Codex of 1968 describes Potassium Iodide as an expectorant and useful in providing a firm texture to thethyroid gland before surgery. None of the references are as a cancer treatment ( 1521 ). It is also said to hasten thedissolution of fibrous lesions, which may be of relevance for some cancers, though the doses given as part of theHoxsey therapy are quite low ( 1521 ).Potassium Iodide can also have an irritating effect on the gastric mucosa and, according to an article critical of thetherapy printed in CA--A Cancer Journal for Clinicians, "toxic reactions“ known as "iodisms," (pimples, excessivesecretion of the eyes or nose, impotence and a mumps-like condition of the salivary glands) may result after doses assmall as 60 mg per day. Because the effects of Potassium Iodide are cumulative, iodisms usually occur in most patientswith long-term use ( 1550 ).The OAM also located one study of the Hoxsey therapy in animals. An independent test conducted by the Center forParasitology at the University of Texas at Arlington found the modulation of antibody response in mice to be greatestfor the Hoxsey formula and Acemin (extract of Aloe) among the substances tested ( 1552 ).CA--A Cancer Journal for Clinicians also cites "a carefully controlled experiment using the Hoxsey tonic in tumourbearingmice showed no difference in tumor size and growth compared with tumors in untreated mice ( 1550, 1551 )"There have been two studies of the Hoxsey therapy in humans. The first is a best-case series of nine long-term cancersurvivors treated with the formula ( 1553 ).The second, a retrospective study by Steve Austin, N.D., was a preliminary study with no controls assessing the survivalof 39 patients with a variety of histologically-confirmed cancers who had been treated at the Hoxsey Clinic. Of the 39patients, 23 were lost to follow-up. Of the 16 remaining patients, nine claimed to have had advanced cancer and twosaid they had suffered local recurrences. Of the 16, 12 said they had had previous unsuccessful treatment withcombinations of surgery, chemotherapy and/or radiation. Ten of the 16 died after an average of 15.4 months, and sixpatients remained disease-free with an average follow-up of 58 months. Sites of the cancers were lung (2), melanoma(2), recurrent bladder cancer, and labial cancer.232

According to Austin:Our Hoxsey results are uncertain due to the preliminary nature of our investigation. Nevertheless, we note that severallong term survivors had very poor initial prognoses. Plausible explanations might include misdiagnoses, small samplesize, and erroneous information from patients. However, we believe any apparently successful treatment of late stagelung cancer and melanoma should provoke interest. ( 1554 )No side effects or toxicities have been reported in the medical literature from the Hoxsey therapy, though some of itsconstituent herbs do have side effects when consumed in doses greater than present in the therapy ( 1555 ).The Hoxsey therapy is currently offered at the Bio-Medical Center in Tijuana, an outpatient clinic that treats all types ofmalignancies. Besides the Hoxsey therapy itself, the clinic offers immunotherapy, homeopathy, and chelation therapy( 1550 ). The treatment also includes supplements and dietary restrictions.Like Essiac and Laetrile, the primary evidence for any possible effect on cancer in humans lies primarily in anecdotesrelated by people who have used it during the decades of its popularity, though vocal advocates for all three approacheshave championed a cause as much as a therapy.Research does indicate that many of the herbs used in the Hoxsey internal tonic or the isolated components of theseherbs have some anti-tumour activity or cytotoxic effects in animal test systems. It is not known whether there might besynergistic effects of the herbs used together. Further, the complete Hoxsey herbal mixture has not been tested for antitumouractivity in animal test systems, with human cells in culture, or in clinical trials. It is also not known whether theindividual herbs or their components that show anti-tumour activity in animals are active in humans when given in theconcentrations used in the Hoxsey tonic.233

Chapter 9.h : Coley's toxinsConcerning Coley's toxins ( 66,196,516 ), these lipopolysaccharides have shown their worth, because, atthe beginning of the treatment, they induce an a-specific stimulation of the immune defenses(provided there is no concurrent or precedent Chemo-Therapy).Probably the positive result of this therapy depends on the fact that they induce an endogenoushyper-thermia due to a temperature (39-40 degrees centigrade), in a way substantially similar to thatdescribed in Hyperthermia anti-cancer, which kills hypoxic cancerous cells present in the innermosttumoral mass.Finally, the induction of thermal shock proteins, determines the specific anti-tumoral activation ofthe immune defenses, in the first place the lymphocytes, for the subsequent specific recognition ofthe cancerous cells.The use, however, of other immune-modulating substances, especially Aloe arborescens, will alsocause an increase in temperature in the patient, though not so high (37.5-38 degrees centigrade),rendering it therefore unnecessary, according to the author, to use Coley's toxins, unless you try toinject them directly into the tumoral mass, as has already been described in other studies, in order toobtain a greater, local activation, made worse, however, by the theoretical risk of liver and kidneyfailure caused by the rapid destruction of a great tumoral mass as has been reported in other studiesusing similar techniques.Chapter 9.i : Bonifacio’s SerumWithin the field of lipopolisaccharides with an immune stimulant action, the ‘Padzahrs’ taken fromthe stomach of goats can also be catalogued. They are effective against many tumors, provided thatno Chemo-Therapy has compromised the immune defenses. They were brought to the attention ofthe media about 30 years ago (Bonifacio’s Serum). SEE Italian book: Liborio Bonifacio: “La mialotta contro il Cancro”, 1970, Ediz. Varesina Grafica Editrice.About 50 patients of Sud Italy: http://www.medicinetradizionali.it/bonifacio2.pdfAbout 50 patients of North Italy: http://www.mednat.org/cancro/bonifacio4.pdf234

Chapter 9.l.: LectinsThese are vegetable proteins present in the seeds of tomatoes, peppers, egg plants, in the flesh ofbeans, in Aloe arborescens, in potatoes, soya (soya lectins), and in other foods (snails).Some of these (soya lectin, snails) have shown that they act selectively on some tumors; others, onthe other hand, cause the agglutination of the erythrocytes in some blood groups.Without acting as direct antigens, they therefore have the prerogative of provoking immunologicreactions such as the blastic transformation of the lymphocytes or the agglutination of the redcorpuscles.Moreover they form immune-complexes with the membrane polysaccharides.The last two effects can be potentially dangerous because they are at the basis of the auto-immuneresponse as, for example, in auto-immunitary diseases.It is also interesting to observe that lectins show a particular structural similarity to integrins, whichare physiological proteins on the surfaces of cells, specifically involved in cell adhesion.On the basis of structural and functional criteria, they are classified into different groups: integrins,caderins, selectins and immune globulins.Their function is to connect between them the intercellular glycocalics which can be homotypical,as for example the platelets, at coagulation level, or heterotypical, as for example in the area of celladhesion and the extra-cellular matrix; that are also able to transfer extra-cellular signals directly tothe inside of cells, because they are trans-membrane proteins able to connect with both the outsideof the cell and the internal matrix of the same cell.It is the prerogative of the lectins to bond with the membrane glycoproteins, such as for exampleConcanavalin A, produced by Canavalina ensiformis (black bean, red bean or Mexican bean),which bonds with all the membrane glycoproteins which contain a-glycosidic or mannosidicgroups, forming aggregates; it can also act as a mythogen, principally for T-Lymphocytes and multicell type agglutin.Some lectins (tomato seeds, capsicum-pepper seeds, potatoes, egg plants and wheat) contain sugarssimilar to Glucose, such as D-Glucosamine and its phosophorylated derivative; these interfere in theglycolithic cycle impeding, by their presence, the use of the glucose.Other components are acetyl-glucosamine, and deoxy glucose, which interact with ATP, the firstinhibiting phosphorylation, the second forming a stable mix with the ATP itself. These substancescan also interfere in the process of moving the sugars through the membranes whose glycoproteinsattached to their outer part therefore represent the target preferred by the lectins.Lectins are transported by metals and from this connection they derive their property of enteringinto circulation and of binding with the cellular membranes; the metals which perform this functionare those with an atomic weight similar to Iron (Cobalt, Nickel, Copper, Zinc, ManganeseChrome…..).The particular predilection lectins have for iron could be one of the causes of Anemia, given thesubtraction of this chemical element from the intestine.Hordeum volgare (barley) malt and the shells of shellfish are factors that inhibit the assimilation oflectins.1. Barley malt: as well as containing Maltose (disaccharide sugar), also contains Destrin (a mixtureof oligosaccharides) and the Diastasis enzyme (which breaks the chains of many oligosaccharides);tetraoses form between these, which can attract the lectins competitively, holding them in theintestinal space and thus preventing them from overcoming the digestive barrier.2. Shellfish: their shells are rich in Chitosane which binds the lectins competitively, holding them inthe intestinal space and thus preventing them from overcoming the digestive barrier.235

Capter 10:Non-insulin-dependent Diabetes mellitus or adultdiabetes, or Secund TypeThere are 5 subgroups of diabetes mellitus:Type 1, insulin-dependent diabetes (IDDM), or juvenile diabetes, or First Type;Type 2, non-insulin-dependent diabetes (NIDDM), or adult diabetes, or Secund Type;Type 3 or secondary diabetes;Type 4, gestational diabetes;Type 5, diabetes caused by impaired glucose tolerance.This work aims at analysing only Type 2 diabetes: non-insulin-dependent diabetes or adult diabetes(NIDDM). This one is almost always associated to obesity.Many medical works were written about Type 2 diabetes.The following are some introductory notes by Cherie Calbom and Maureen Keane in “La salute coni succhi di frutta e verdura”, Edition Tecniche Nuove, pages 90-91:“….Taking some exercise can be very useful during the treatment of diabetes. Many benefits wereobserved, such as greater sensitivity to insulin with a following reduction in injections, greaterglucose tolerance, an increase in the number of insulin receptors, a lowering of the amount ofcholesterol and triglycerides in the blood with an increase in HDL levels and a more considerableloss of weight in obese diabetic patients. However, the exercise programme for diabetic patientsmust be carefully developed in order to avoid risks.Diet could be play the most important role in the treatment of diabetes. James Anderson developeda diet - rich in vegetable fibres with high amounts of carbohydrates (HCF)- which was wellaccepted by the scientific community, resulting to be the most suitable diet for this kind of disease(Anderson J.W.: High-carbohydrate, high fibre diets for insulin-treated men with diabetes mellitus, Am. J. Clin. Nutr.1979, 32, pages: 2312-2321; Anderson J.W.: Metabolic effects of high-carbohydrate high-fibre diets for insulindependentdiabetic individuals, Am. J.Cl.in. Nutr. 1991, 54, pages: 936-943).The diet suggested by the American Diabetes Association and the American Dietetic Association –which use lists of substitute products – is considered less effective than the HCF diet by manydoctors and nutritionists. The diet consisting of substitute product is much richer in proteins,cholesterol and fats compared to the HCF diet and bases itself on 6 groups of foods: milk,vegetables, fruit, bread, meat and fats. Thirty-five per cent of total caloric requirement come fromfats. As demonstrated, this amount contributes to the development of atherosclerosis. The amount ofcarbohydrates is much lower than in the HCF diet, whose 40-45% of total calories derive fromcarbohydrates. Some scientific researches demonstrated that a diet rich in complex carbohydrateskeeps the level of glucose in the blood better under control. Seventy-seventy five per cent of theHCF diet are constituted by complex carbohydrates (vegetables, fruit, legumes and wholemealcereals); fifteen-twenty per cent by proteins and only five-ten per cent by fats. It is advisable tofollow the modified HCF diet (MHCF) as it contains fewer treated cereals and does not include fruitjuices, low-fibre fruit, skimmed milk and margarine. The MHCF diet is described in the followingsection “Modifications to the diet” (SEE Chap. 10.1)236

Chap. 10.1.:Modifications to the diet1) Following a totally vegetarian diet or a modified vegetarian diet (with fish and poultry once aweek). It was demonstrated that this diet reduces the risk of dying of diabetes.2) Eating garlic and onion abundantly. It was demonstrated that these foods significantly help tolower the amount of sugar in the blood:[Sharma KK.: Antihyperglycemic effect of onion: effect on fasting blood sugar and induced hyperglycaemia in man,Indian J.Med. Res., 1977, 65, pages: 422-429] ;[Jain RC.: Hypoglycaemic action of onion and garlic, Lancet, 1973, 2, page: 1491] ;[Silagy C.: Garlic as a lipid lower agent a meta-analysis, J. R. Coll. Physicians London, 1994, 28, pages: 39-45] ;[Phelps S: Garlic supplementation and lipoprotein oxidation susceptibility, Lipids, 1993, 28, pages.: 475-477] ;[Legnani C.: Effects of a dried garlic preparation on fibrinolysis and platelet aggregation in healthy subjects,Arzneimittelforsch, 1993, 43, pages.: 119-121] ;[Silagy CA: A meta-analysis of the effect of garlic on blood pressure, J.Hypertens. 1994, 12, pages.: 463-468] ;[Kawasakishi S.: New inhibitor of platelet aggregation in onion oil, Lancet, 1988, 2, 330] ;[Louria DB.: Onion extract in treatment of hypertension and hyperlipidemia: a preliminary communication, Curr. Ther.Res., 1985, 37, pages.: 127-131].SEE also bibliography to: 1851-1864Note of the author (Doctor Giuseppe Nacci): unfortunately the current introduction of GMO garlic and onion(Genetically Modified Organism) represents a serious and unjustified obstacle to this therapy, not only with regard todiabetes treatment, but also to other chronic-degenerative diseases.3) Consuming raw foods and juices of raw vegetable abundantly. It was observed that these foodsare very beneficial to diabetic patients. Doctor John Douglas found out that fibre-rich carbohydratesare better tolerated by diabetic individuals if eaten raw and help to stabilize the level of sugar in theblood. Furthermore it was demonstrated that these foods reduce the desire to eat more. Doctor MaxBircher-Benner, founder of the renowned clinic with the same name, used raw vegetable juices inhis dietary treatments, including that for diabetics.Fruit juices should be avoided. It is allowed to use some thin slices of apple to sweeten a vegetablejuice, but if this minimal amount of fructose increased the level of glucose in the blood, it isadvisable to eliminate it.All sugars should be eliminated. Saccharose was associated with poor glucose tolerance. All simplesugars (sweeteners) are eliminated in HCF and MHCF diets. It was proved that saccharose andfructose increase the level of total cholesterol and LDL, the amount of triglycerides and uric acid inthe blood. It is inadvisable to use artificial sweeteners because of their risks to health.Possono essere utili particolari piante come la Trigonella foenum graecum ( 1846-1850, 2024-2026 ),Vaccinium myrtillus ( 2052-2057 ) Glycirrhiza glabra ( 1865 ), Rubus fruticosus ( 1866 ), Panax ginseng ( 1867,2051 ), Arctium lappa ( 1868 ), Aloe species ( 1869-1871 ), Momordica carantia ( 1872-1874, 2040-2043 ). Molti sonoquindi gli Studi condotti sulle diete più adatte ( 2005-2023 ).Note of the author of this book (Doctor Giuseppe Nacci): this therapy is similar to the old Gerson therapy, which wasmodified for the treatment of Type 2 diabetes mellitus (SEE Charlotte Gerson: “The Gerson Therapy). Gersonmaintained that the main cause of this disease is essentially the high amount of cholesterol in the blood, which makes itimpossible for cell receptors to absorb insulin. This theory is only partially shared. Besides, chemical-pharmaceuticalmultinationals invested considerable capitals in order to put on the market the “Statins”, which seem to find favour withmedical class despite well-known cases of death caused by “Lipobay”.237

At this point we should ask ourselves why the cholesterol is so high in the blood of patients affectedby Type 2 diabetes mellitus and whether its reduction through the diet and not through drugs suchas the “statins” could really cure this disease, in other words a treatment free ofchemical/pharmaceutical therapies at last.Alessandro Formenti and Cristina Mazzi, in their wonderful book (“Cereals and legumes in the dietfor the health”), Edition “Tecniche Nuove”, masterfully outlined the relation of cholesterol to thediet:“The cholesterol plays a significant role in the organic physiopathology. It is a steroid alcoholnecessary for the nervous system, the brain and the cell membranes. It is a precursor of varioushormones, vitamin D and bile salts. Naturally, the cholesterol is above all present in animal fats(meat, lard, milk and by-products, eggs, sausages, fish, molluscs and shellfish), whereas it is almostabsent in vegetal products.Human body daily produces 2 grams of cholesterol (endogenous cholesterol), 1-1.5 grams originatein the liver; the rest is synthesized in the adrenal gland, in the cutis and in the intestinal mucosa.Further cholesterol (0.3-0.5 grams) is introduced in the body through food (exogenous cholesterol).Consequently, the amount of endogenous cholesterol is 3-4 times larger than that introduced byeating. Good levels of cholesterol in the blood range from 180 to 200 milligrams/ decilitre.The blood is principally an aqueous medium, in which fats cannot circulate because of their waterrepellentproperties. Thus, the cholesterol is carried by lipoproteins, which are protein carriershaving good affinity with water.Up to the present time three main types of lipoproteins which transport fats are known:Very Low Density ProteinsLow Density Proteins, LDLHigh Density Proteins, HDLRecently it was observed that also residual chylomicrons and intermediate density lipoproteins(IDL) cause the formation of atheromatous plaques when they are largely present in the blood.About 80% of cholesterol is removed from the body after its conversion into bile acids, whichare eliminated through the feces after being poured in the duodenum and then in theintestine. However, this process is largely influenced by the type of diet chosen.People eating foods rich in protein and poor in vegetable fibres have a great number of microorganismsin their colon, such as bacteroides, Escherichia coli, bifidobacteria and other Gramnegativeflora, which degrade bile acids. Also thanks to a passage speed reduced by “fine” diets,these are almost reabsorbed and go back to the liver through the portal vein (enterohepaticcirculation).It should be noted that some substances produced by the degradation of bile acids are also powerfulcarcinogenic agents, i.e. 3-methyl-methylcholanthrene and, in case of neutral pH, nitrosamines.Moreover, lithocholic acid – which reduces the hepatic conversion of cholesterol into bile acids – istoxic.Consequently, besides originating substances which favour colon cancer, a diet poor in fibres alsocreates a condition in which a smaller amount of cholesterol is converted into bile acids in the liverand then excreted in the duodenum; furthermore, old cholesterol adds to that daily synthesized.As it was often demonstrated by studies on human beings and by animal experiments the mostdirect and important way used by the body to get rid of excess cholesterol is the colon and thedefecation. Surely the modern diet – which is poor in fibres and rich in animal proteins –significantly contributes to cumulating cholesterol in the bloodstream. On the contrary, a diet rich incarbohydrates, vegetables and cereal bran accelerates the intestinal passage and favours thepresence of mostly Gram-positive flora in the colon, such as streptococci and lactobacilli. In this238

way, the degradation of bile acids is significantly reduced. These are scarcely reabsorbed andquickly and massively excreted through the feces.Thus, the level of hematic cholesterol decreases first of all because great amounts are expelledthrough the alvus and then because the liver is stimulated to transform cholesterol into bile acids,which are immediately eliminated.Furthermore, this kind of saprophyte flora produces volatile fatty acids which are able to inhibit thecholesterol synthesis, have a good energy value and, to a lesser extent, vitamins, amino acids andoligopeptides. Moreover, the fermentations in the human large intestine can degrade toxic andcarcinogenic compounds.Also the lifestyle influences cholesterolemia: the level of HDL cholesterol is higher in activepeople, moderate drinkers, non-smokers; whereas LDL cholesterol is higher in sedentary people,smokers and obese individuals. Further risk factors are heritability, hypertension and too muchalcohol…”.Doctor Catherine Kousmine treated Type 2 diabetes mellitus by prescribing a correct diet and byreactivating the functionality of cell walls, tissues (for example intestinal tissue) and organs (forexample the liver), in particular by using vitamin F (polyunsaturated fatty acid) and by eliminatingfoods rich in saturated fatty acids such as butter, margarine, etc…According to the author, doctor Giuseppe Nacci, vitamin F is really important for the generalbiochemistry and in particular it is effective against the onset and the progression of diabetes andother chronic-degenerative diseases; the insulin binds with a receptor of the cell membrane, thusbeginning a complex series of biochemical reactions in the cell. Glucose transporters, known asGLUT4 molecules, leave their endocellular region moving to the inner surface of the cell membrane((Lienhard G.E.: Le Scienze, 283, marzo 1992). They then move to specific regions of cell membranes,where they detect and hook glucose molecules that they afterwards transport inside the cell, i.e. inthe mitochondrions, where glucose is converted into energy.Most of the molecules involved in the absorption of glucose molecules on surface and in theirtransport in mitochondrions are made of lipids, i.e. polyunsaturated fatty acid…But also other vitaminic substances, such as Zinc ( 1875-1893, 2044-2046 ), Magnesium ( 1960-1975, 2047 ),Selenium ( 1894-1900 ), Chromium ( 1908-1937 ), Rame ( 1901-1906 ), Potassium ( 1981-1984,2048 ), Manganese ( 2049-2050 ), Vanadium ( 1938-1946 ), vitamin E ( 1823-1838 ), vitamin C ( 1947-1959, 2038-2040 ), Tiamina ( 1976-1980 ),Niacina ( 1991-2002, 2027-2037 ) and others, are involved in this process.Consequently, large amounts of cholesterol and low levels of vitamin F and natural vitamins, suchas vitamin C, are regarded as the cause of a metabolic system malfunctioning.Therefore vitamin F deserves an in-depth analysis; for further information please SEE chapter 9.According to the author, Doctor Giuseppe Nacci, a chronic deficiency in vitamin C also can have anessential role in diabetes, especially if associated to particular drugs such as Statins.239

Vitamin C deficiency and the threat of StatinsAs underlined by independent scientific papers about the issue of “Lipobay”, the disposal ofcholesterol cannot take place by using drugs such as Statins because it can be lethal. The humanbody is believed to compensate for chronic deficiency in vitamin C with cholesterol on connectivetissues lacking in this vitamin. Differently from almost all other animals, humans and monkeys arenot able to produce vitamin C. This explains their predisposition to vascular diseases such asmyocardial infarction and strokes. The lack of vitamin C in today’s diet forces the patient’s body touse cholesterol to “keep together” tissue collagen fibres, thus endangering some delicate “strain”areas such as arterial walls which tend to form atheromatous plaques. According to scientificliterature, these plaques can regress if very high amounts of vitamin C and other vitamins are taken.Lipobay and other statins eliminate cholesterol from the human body in an unnatural way thuscausing ruptures of important arterial walls as their “glue” (cholesterol or enough vitamin C) ismissing.Note: a sudden and unnatural lack of cholesterol in the human body could also lead to other diseases such as MultipleSclerosis.To sum up, it can be said that therapy for NON-insulin-dependent diabetes mellitus, also known asadult diabetes or Type 2 diabetes mellitus, must base itself on the following considerations:1) Cell insulin receptors are in Down Regulation because of high amounts of cholesterol circulatingin the bloodstream.2) Cholesterol must be assimilated as little as possible through food but since it is mostly producedby the liver it must be expelled every day through the feces.3) The disposal of cholesterol must not take place by using pharmacological products such asstatins. This can be fatal because of little-known severe diseases linked to deficiency in vitamin C(infarction, stroke) and in cholesterol in patients without particular hepatic enzymes (suspectedonset of Multiple Sclerosis).4) Therefore, it is more advisable to follow a therapy which aims at reactivating the intestinalfunctionality in order to eliminate “naturally” excess cholesterol: it is recommended a modifiedGerson therapy in case of metabolic disorders, with addition of some variants developed byKousmine, in particular a wide use of vitamin F.Note: this therapy is here outlined but it is important to remember that only a doctor can prescribe itand that doctor Nacci waives all responsibility in case of people who want to undergo it withoutconsulting a doctor.1) Reactivation of intestinal saprophyte bacterial flora2) Elimination of parasites, fungi and Gram-negative bacterial flora3) Reactivation of normal intestinal wall4) Vitamin F integration5) Vitamin C integration ( 1947-1959, 2038-2040 )6) Vitamin E integration ( 1823-1838 )7) Acido alfa-Lipoico ( 1839-1846 )The diet should be poor in glucose, yeasts, proteins (if containing all 9 essential amino acids), folicacid, vitamin B17:Therefore the following foods should be excluded:meat, fish, eggs, milk (it is liquid meat), milk by-products ( 1985-1990 ), mushrooms, algae, pollen.240

Patients cannot eat legumes and cereals during the same meal. Cereals are preferable to legumes.Among cereals it is advisable to eat emmer (70 grams for plate).It is advisable to exclude Sodium from the diet (Sodium chloride or sea salt).The glycemic curve, caused by the introduction of food, should be always under certain values.Some raw foods could be listed with the specification of the amounts to be taken every hour asacceptable values of maximum glycemic curve tolerable for a diabetic patient.Only the doctor can establish the best associations among fruits and/or vegetables.Some useful spices to add to emmer pasta or fruit and/or vegetable shakes are:Anethum graveolens (Dill, Fennel),Ocimum sanctum or tenuiflorum (sweet Basil),Cinnamomum zeylanicum (Cinnamon),Elettaria cardamomum (Cardamom),Eugenia caryophyllata or Caryophyllus aromaticus (Cloves),Coriandrum sativum (Coriander),Carum carvi (Caraway),Carum nigrum or Nigella sativa (black Caraway or black Cumin),Curcuma longa (Curcuma),Artemisia dracunculus (Tarragon),Melissa officinalis (lemon Balm),Mentha species (Mint),Origanum vulgare (Oregano),Majorana hortensis (sweet Marjoram),Schinus molle (pink Pepper),Capsicum frutescens or annum (red Pepper, Paprika),Cochlearia armoracia (Radish),Rosmarinus officinalis (Rosemary),Sinapsis arvensis (wild Mustard),Sinapsis alba (white Mustard),Thymus vulgaris (Thyme),Crocus sativus (saffron Crocus),Zingiber officinalis (Ginger).It can also be useful to drink one spoon of apple vinegar of high quality (obtained from Cider oforganic apples stored in oak or chestnut barrels for at least 6 months), diluted with half glass ofwater.241

Marginal note:Diabetes and the grave threat of Genetically Modified OrganismsThe curative effectiveness of these particular vegetarian diets lies in the elimination of foodscontaining all potential cell growth factors (useful also to germs of intestinal putrefaction, fungi andparasites), in particular in the exclusion from the diet of food combinations containing ALL 9ESSENTIAL AMINO ACIDS (Valine, Isoleucine, Leucine, Lysine, Methionine, Histidine,Tryptophan, Phenylalanine, Threonine), nucleic acids, vitamin B17, folic acid and relatively also ofpara-aminobenzoic acid [PABA].Once foods containing all the above-mentioned substances were only those of animal origin (meat,fish, eggs, milk, cheese, butter, etc.).Gerson and other authors (including the Chinese and Indian medicine) forbade from taking them for1 year al least.Thus the vegetarian diet proved to be successful, i.e. a diet consisting only of fruit and vegetables,including cereals and legumes.Cereals and legumes are rich in proteins and the fact that they are used anyway by Gerson and manyother schools of Western, Indian and Chinese medicine in the treatment of Diabetes mellitus couldsurprise.They were used because cereals or legumes alone do not contain ALL 9 ESSENTIAL AMINOACIDS.But if they are eaten together during the same meal they cause the assimilation of all 9 amino acids.For this reason you should not eat Pasta (or Polenta or Rice) together with Legumes in order toavoid the integration of ALL 9 ESSENTIAL AMINO ACIDS (8 contained in cereals + 8 containedin legumes), with a nutritional effect similar to that obtained from eating Meat (after all, a plate ofPasta and beans was once called “the meat of the poor”).Furthermore, you should not eat potatoes with legumes or cereals.Unfortunately, nowadays GMO Biotech Multinationals are spoiling the food chain by introducingpotatoes, cereals and legumes enriched with ALL 9 ESSENTIAL AMINO ACIDS.In particular: Soya, Beans, Peas, Maize, Rice, Soft Wheat (Bread), Durum Wheat (Pasta), Potatoes.Another real problem is that a lethal insecticidal poison is synthesized by the plant itself in case ofGMO foods, i.e. the Bacillus thuringiensis. It proved to be dangerous in tests on laboratory animals(mice), which were fed with GMO Maize and Potatoes. (SEE Chapter 2 and 3).Another serious threat posed by GMOs is that many of them contain Retroviruses in order toprovoke genetic modifications in the plants.Note 1: organic ChromiumOrganic Chromium – contained in the plants – could be one of the most important multivitaminic or provitaminicfactors for normal pancreas functionality ( 1908-1937 ), as are organic Zinc for deficiency prostatic disorders and organicIodine for deficiency thyroid disorders.Note 2: The modern pharmacological treatment and the great waste of the financial resourcesAfter diagnosing diabetes, the modern medical treatment consists in prescribing drugs which aresubstantially useless and expensive for the society: oral hypoglycaemics and insulin.It is important to say, first of all, that neither insulin nor hypoglycaemic drugs have a therapeuticeffect on diabetes: none of these medical strategies was studied to normalize the cell absorption ofglucose.This medical treatment increasingly causes disability and untimely death because of infarctionand/or kidney failure and/or collapse.242

Chap. 10.2.:Oral hypoglycaemic drugsOral hypoglycaemic drugs appeared on the market 10 years ago. They are divided into 5 groups:biguanides, glucosidase inhibitors, meglitinides, sulfonylureas, thiazolidinediones.Biguanides:They lower the level of sugar in the blood in three different ways:1) by inhibiting the normal glucose release from the liver reserves;2) by interfering with the intestinal absorption of glucose present in ingested foods (carbohydrates);3) by increasing the peripheral absorption of glucose.Glucosidase inhibitorsThey were developed to inhibit the pancreatic amylase enzymes, which are essential for thedigestion of carbohydrates. Theoretically, if the digestion of carbohydrates is inhibited, the level ofsugar in the blood cannot be high.MeglitinidesThey were developed in order to stimulate the pancreas to produce insulin in a patient who hasprobably already a high level of insulin in the bloodstream. Only rarely this level is measured bydoctors. Obviously, these drugs are often prescribed without knowing the pre-existing insulin levelbut it is generally not known that a high insulin level may be almost as dangerous as a high glucoselevel.SulfonylureasThey are another group of pancreas stimulators used to increase insulin production. Beforeprescribing these drugs, doctors rarely measure the insulin in serum. These medicines are usuallygiven to people suffering from type 2 diabetes – many of them already have high ineffective insulin– and it is generally known that they cause, as side effect, hypoglycaemia.ThiazolidinedionesThey are thought to cause liver cancer (confidential data).InsulinToday insulin is prescribed for both type 1 diabetes and type 2 diabetes.Insulin replaces that no more produced by the body. This treatment – although it is necessary tokeep alive people with type 1 diabetes – may be criticized if given to patients with type 2 diabetes.243

Chap. 10.5.:Healing with Gerson-like dietRecovery time with Aloe arborescens, organic Germanium, vitamins A, C, E, F and vegan diet isone year or more.Vascular disorders caused by high chronic level of glucose are solved quite quickly. But the effectsof retinopathy and peripheral neuropathy are variable.According to private hospitals of the “health” – above all those who follow the Gerson-like diet –kidney recovery cannot occur when the damaged exceeds more than 20% of their normalfunctionality.The fine capillaries of renal glomerulus basal membranes begin to decay because of diabetes.They are replaced by cicatricial tissue making the damage irreversible.As far as eyes are concerned, cicatricial tissue provoked by retinal hemorrhages – which werecaused by laser operations – does not allow the recovery from the damage.Finally, in order to clean arteries many years of diet are necessary.244

Chapter 11Multiple Sclerosis (or Sclerose en plaques)As far as treatments for Multiple Sclerosis (MS) are concerned, note should be taken of the greatdiscoveries made by Catherine Kousmine in the 1960’s. She successfully cured hundreds of casesof MS, about fifty of which are reported in her well-known book Multiple Sclerosis is curable.Then, the Standard Treatment Protocol according to a neurologist of the University of OregonHealth Science Center in Portland is indicated. Finally, a clinical case of a patient suffering fromMultiple Sclerosis is reported. The patient was partially treated with both of the above-mentionedmethods in addition to a basic protocol which was developed by an Italian physician and iscurrently used to treat a 30/40-year patient.It equally deserves mention that the Gerson Therapy also gave good results in the treatment forMultiple Sclerosis. In her book, The Gerson Therapy (chapter 17), Charlotte Gerson describes MSas an autoimmune disease. Furthermore, the author states that the repair process of the damagedmyelin sheath may cause a temporary worsening of symptoms, which usually frightens patients aswas observed in two clinical cases.Recently, the first diagnostic test based on glycopeptide Csf114 has been patented as Ms Pepkit. Itis used to show the presence of auto-antibodies linked to the worsening of the disease.Chap. 11.1.:Multiple Sclerosis Etiopathogenesis and Therapy According toCatherine KousmineAccording to Dr Catherine Kousmine, Multiple Sclerosis has an autoimmune etiology.In the case of MS, it is the nerve-insulating myelin sheath that comes under assault. The disease isstrictly connected with a nutritional deficiency of essential vitamins, which can be cured with ahealthy diet eliminating any kind of digestion disorder causing toxic products. If diagnosed in itsearly stages and treated before life-threatening complications arise, i.e. in the first 2 or 3 years afterthe diagnose, MS can be cured in 75% of cases. This percentage was given by Dr Kousmine and isthe result of her clinical experience and of the control of hundreds of cases which were followed formore than 20 years. If the disease is advanced, Kousmine’s method makes patients’ conditionsstable. In some rare cases, extraordinary improvements are possible. For further details onKousmine’s Therapy, SEE her well-known book: “ Multiple Sclerosis is curable”.245

Chap. 11.2.:Etiopathogenesis and Therapy for MS Developed According to aNeurologist of the University of Oregon Health Sciences Center inPortlandA study conducted at the University of Oregon did not focus on MS etiopathogenesis but rather on apossible diet-based treatment. The study confirms that the disease affects people from 25 to 40years of age. It also indicates that MS progresses slowly while patient’s conditions worsen. Itssymptoms are: vision and speech difficulties, dizziness, bladder and intestines disorders, loss ofbalance and emotional instability. According to the study, patients should be on rest, do physicalexercise and eat a well-balanced diet. All this is necessary for the nervous system to work properly.In some MS cases, vitamin B12 was used to improve the balance of patients when standing orwalking. Vitamin B13 also proved beneficial in the treatment for MS. At the University of Oregon,the therapy was based on a concentrated integration of minerals and a controlled diet. Foodcontaining saturated fats was eliminated and replaced with food containing unsaturated fatty acids.Food such as cake mixes, cheeses, sweets and other chemically treated products should not be eatenbecause they contain hidden or unknown amounts of saturated fats. Furthermore, patients should eatwholemeal bread and cereals and take wheat germ or vitamin E to prevent the oxidation ofunsaturated oils once they are introduced into the body. Fewer relapses, more energy and higherendurance in working and walking, as well as longer life expectancy are the beneficial effectsobserved on patients. When the treatment was administered in the early stages of the disease, whenthere were still few, not so visible symptoms, 90-95% of cases remained unchanged or evenimproved during the following 20 years.Nutritional elements recommended by a neurologist of the University of Oregon:Vitamin B Complex: 150 mg a dayCholine: 750-1,500 mg a dayVitamin C: 1 gram a dayVitamin E: up to 1,800 I.U. a dayVitamin F: from 1,500 to 3,000 mg a dayPangamic acid (Vitamin B 15): 50 mg a dayVitamin B 13 with calcium and manganese: 1 gram a dayLecithin: various amountsProteins: various amounts246

Chap. 11.3.:Personal Clinical CasesBesides a deficiency of polyunsaturated fatty acids and important vitamins (or a diet rich insaturated fatty acids), the cause of MS could also be a lack of cholesterol due to an enzymatic defectof the liver. This hypothesis, which is shared, was formulated by an Italian physician with whomthe author is cooperating in treating a patient.It is thought that this enzymatic defect controlling cholesterol synthesis can be discovered by usingdrugs (statins) which make it worse. The enzyme used is HMG-CoA reductase.At present statins are widely debated, especially after “Lipobay/Baycol” was withdrawn from themarket ( 1278, 1279 ).As is well documented in medical literature, Cholesterol generates Pregnenolone, which issynthesised into Progesteron and/or 17 OH Pregnenolone, which originate 17 OH Progesteron.17 OH Pregnenolone also generates Dehydroepiandrosterone. Dehydroepiandrosterone and 17 OHProgesteron result in Androstenedione. Androstenedione creates Estrone and/or Testosterone.Testosterone originates Estradiol.It is therefore advisable to keep under observation all patients who underwent long anti-cholesteroltherapies based on anti-enzymatic drugs, such as statins, because they could develop MS.The therapy given to an Italian patient was very similar to that used by Dr Kousmine and by theresearcher of the University of Oregon, with the addition of 14-20 organic eggs a week, bluefish(Omega-3) and pumpkin seeds oil. At present, the patient’s conditions have improved significantlyand his hormonal blood profile has almost normalised.The use of flax-seed oil (cis-cis linoleic fatty acid) and Borrago officinalis seed oil (homo linolenicfatty acid) is highly recommended. Recently, a particular phytotherapy product has been tested:Olea europaea. It is very rich in DHEA but diet should include no food containing many essentialamino acids.Principles of treatment, which are also shared with the above-mentioned therapies (Kousmine,University of Oregon):1) excluding SATURATED fatty acids from diet;2) taking vitamin F abundantly (polyunsaturated fatty acids);3) taking vitamin E abundantly.The patient was diagnosed with MS during the first months of 2003, also by using MagneticResonance. The patient was with “Atopic Dermatite” on the foodsAfter 1 years, the Atopic Dermatite was aut.During the last two years, the blood hormones that are synthesized from cholesterol were kept undercontrol. As the amount of total cholesterol improved, gradual progresses of patient’s clinicalconditions were observed.Blood examinations every 3-4 months are therefore deemed necessary and useful in the mentionedtreatments for MS. The following values should be examined (both in men and in women):Cholesterolemia (HDL, LDL and total),Triglycerides,DHEA,17 Beta-estradiol,247

Prolactin,Follicle-stimulating hormone or Follitropin (FSH),Luteinizing Hormone or Luteotropin (LH),free and total Testosterone,THS,FT3,FT4.Equally useful, though on different grounds:Complete Blood Count (with special attention to EOSINOPHILS),ESR,C3,C4,Glycemia,Creatinemia,Azotemia,Electrolytes (Na, K, P, Ca, Mg, Cl, Zn).Total cholesterol: normal range 150-240 mg per 100 ml of bloodFebruary 2003: 94May 2003: 105September 2003: 111December 2003: 115March 2004: 100June 2004: 102September 2004: 138December 2004: 136March 2005: 115June 2005: 116January 2006: 121October 2007 : 118248

Chap. 12:Tamoxifen and natural phytoestrogensNella cura del cancro al seno, da molti anni, accanto alla Chirurgia, alla Radioterapia e allaChemioterapia, è ormai d’abitudine somministrare anche sostanze chimiche sintetiche anti-ormonaliche vanno a bloccare i recettori cellulari delle cellule mammarie, agendo sostanzialmente come“blocco” di crescita su tutte le cellule umane recettive ai ben noti ormoni femminili Progesterone eEstrogeni.Fra queste sostanze chimiche sintetiche anti-ormonali di ormai ampio impiego in Oncologia, la piùconosciuta è il ben noto Tamoxifene.There is an interesting bibliography about Tamoxifen drug ( 795-805 ).Tamoxifen is a synthesized hormone originated from a well-known carcinogenic substance, i.e.DES (Diethyl-stilbestrol). This substance is extremely dangerous because it can cause wombtumour according to the International Agency for Research on Cancer.In November 1999, the National Cancer Institute stated that “…for women over 60 years benefitsare greater than risks, but for younger women the contrary is true: the risks are greater than thebenefits…”Some experiments carried out on animals (rats) showed that Tamoxifen induces liver malignanttumours in 15% of rats treated with a daily 20 mg dose of Tamoxifen and in 71% with a 40 mg dose( 796 ).A Swedish study conducted on 931 women recorded 3 cases of liver tumour and 23 cases of wombcancer, with a frequency 6 times higher than the average.Moreover, all patients with metastasis become “resistant” to the drug; the study carried out by theNCI and a research done in Scotland demonstrated that using Tamoxifen for more than 5 years canincrease the cancer growth in the breast and in other parts of the body. In November 1995, theNational Cancer Institute suddenly interrupted the study of Tamoxifen. Afterwards, the NCIannounced that Tamoxifen cannot be used for more than 5 years (after 5 years there are no furtherbenefits of Tamoxifen, in fact it can be detrimental to health…). The NCI study demonstrated that33 out 6.000 women taking Tamoxifen for 2-5 years developed endometrial cancer; 17 womensuffered from blood clots in lungs and 130 from blood vessels thrombosis.Tamoxifen can indeed cause hormonal disequilibrium, osteoporosis, retinopathy eye disorders,cornea alterations, optic nerve damage and cataracts. All these side effects can be irreversible, evenif the treatment is suspended ( 805 ).It was estimated that less than 20% of women taking Tamoxifen suffer from severe side effects, butif these negative effects occur they can be permanent or cause even the death of the patient.According to other studies, it is not sure that substitute hormonal therapy can be associated tohigher risks of breast cancer ( 942-946 ).Numerous research groups began studying the estrogenic activity of natural substances concentratedin some plants. They are called phytoestrogens ( 947-949 ) and are known since ‘40s.249

These substances can be extracted from Glicine maxima, Dioscorrea composita, Trifolium pratense,Linum usitatissimum and other plants.Phytoestrogens – or vegetal estrogens – have no structural similarities with the estrogens producednaturally. Phytoestrogens can be divided into 3 main groups: Isoflavones (soy, clover), rye, wheat,sesame seeds, Linum usitatissimum seeds, Coumestans (Trifolium pratense, bean sprouts, sunflowerseeds) ( 951-953 ).Trifolium pratense contains all four Flavones, which play an essential and important role in biology:Biochanin A, Genistein precursor, Formononetin, Genistein and Diadzein, which is metabolizedinto Equol ( 954 ).The effects of the different phytoestrogens depend on species, tissue and number of estrogenreceptors in a tissue. There are at least two different receptors (ERalfa and ERbeta) with differenttissular distribution and bond affinity. This can explain the different estrogen’s effects on the tissuesof the body in vivo ( 955 ).Therefore, isoflavones can be considered as “Selective Estrogen Receptor Modulators” (SERM).Basically, Isoflavones act as weak estrogens on Estrogen receptors, they are able to favour the boneformation and to reduce the risks of cardiovascular diseases but they are not strong enough toinduce hormone-dependent tumours ( 956-957 ).Since high levels of estrogens were correlated to breast tumour and other hormonal tumours,isoflavones can be effective by linking estrogen receptors and blocking the harmful effects of mostpowerful Estrogens, thus acting as “general anti-estrogens”.Other non hormonal anti-tumoral mechanisms were proposed. Genistein probably inhibits thegrowth of cancer cells both in vivo and in vitro; one of the proposed mechanism is the inhibition oftirosin kinase … ( 958 ).Moreover, Genistein allows the differentiation of some malignant cells in benign cells – may bepreventing carcinogenesis ( 959 ) – and inhibits angiogenesis ( 960 ).Genistein is also an antioxidant, it prevents free radicals from damaging the cell ( 961-962 ) and caninhibit the growth of cancer cells, by inducing changes in the synthesis and the metabolism of theTransforming Growth Factor 1 (TGF) ( 963 ).High levels of Genistein seem to block the cell proliferation in vitro; but in vivo it produced humancell proliferation of breast tumour in rats, whereas it did not influence the growth of estrogenindipendenttumour cells ( 964 ). In culture, Genistein inhibits cells of estrogen-independent mammarytumour, but this effect does not take place if the tumour cells are implanted in mice without thymus( 965 ).250

Chapter 13:Neurological diseases, cardiovascular diseases andageingAgeing, cardiovascular diseases and related neurological diseases such as Alzheimer’s disease,Amyotrophic lateral sclerosis or Lou Gehrig’s disease, Parkinson’s disease and Parkinsonisms,Atherosclerosis of cerebral circulation, senile dementia, strokes etc. are often connected with:1) Deficiency of natural vitamins able to guarantee proper blood circulation in all brain regionskeeping capillary, arteriolar and venous walls healthy.2) Deficiency of natural vitamins able to protect the cell from oxidative stresses, thus delaying itsdeath.3) Presence in cerebral and systemic blood flow of different types of toxic substances such asMercury, Aluminium, fine dust particles etc. which damage cardiovascular walls and cells of tissuesand organs such as heart, liver, kidneys, etc.All the above-mentioned conditions are therefore linked to blood flow disorders of vital organs andconsequently to the complex physiopathological state known as ageing.251

Chap. 13.1.: AgeingGoing back to the brain, a real “Organula in Organu”, it can be said that progressive vasculardeficiency of blood circulation causes progressive organic decay of its most sensitive areas leadingto associated diseases (Parkinson, Alzheimer, etc).Of special interest is another inner mechanism which does not involve the capillary, venous andarterial walls of blood flow but the cell itself. This process can be seen as cell ageing, which istoday considered unstoppable.As a matter of fact, the rate of ageing depends on diet and oxidative stress ( 1239 ); in addition to that,captain Diamond’s story is often mentioned in medical books and is worth being cited here.He was born in Plymouth Mass on 1st May 1796, in the days of the Italian campaign conducted by an obscure Frenchgeneral who made himself called Napoleon, and died in 1916, during the First World War, at no less than 120 years ofage, because of a dietary mistake that he should not have made at his age. The story of this sprightly old man wasreported in a medical book by Dr. Threshed who, in 1915, described him in these terms: “… this captain did not seem tohave aged much between his 96 and current 119 years, and I saw this with my own eyes…”. The nice old man, at over110 years of age, allowed himself the luxury of writing a book on his particular diet: “The secret of living long andbeing happier”, in which he wrote he became vegetarian at 40 years, in 1836, i.e. when he was – so to say – veryyoung…Proper control of free radical metabolism could really extend life expectancy until reachingadvanced ages ( 1237 ).At this point, a short digression about telomeres, i.e. human DNA ends, is necessary.Telomeres and ageingTelomeres shorten after every cell division. After about 50 replications the cell can no longer divide( 1241 ). When a telomere is deleted, the chromosome and consequently the cell die. Therefore, innormal human cells telomere length determines lifespan ( 1242 ). If telomeres are congenitally short, arare genetic disease known as “Progeria” will be diagnosed. This disease causes early death at theage of puberty through typical disorders of ageing.An excess of free radicals produces oxidative stresses causing lipid peroxidation in cytoplasmicsemipermeable membranes. When damage exceeds the cell’s ability to make up for it, a new celldivision is needed to produce a new one. Unfortunately, the number of possible cell divisions is notinfinite.Every cell division thus induces an irreversible shortening of telomeres: lipid peroxidationaccelerates telomere shortening as it increases cell substitutions. Finally, it deserves mention thatdamage caused by free radicals tend to worsen with age advancing ( 1240 ). Hence greaterrequirements of natural vitamins.Vitamin E is the most effective “cleaner” of free radicals in the biological membrane ( 1222 ).However, the 600 known carotenoids, e.g. vitamin A, Lycopene, Zeaxanthin, Luteine, etc. can alsohelp carry out this task, as was demonstrated for the prevention of coronary diseases ( 1221 ), strokes( 1243 ) and cataracts ( 1244 ). Lycopene, an antioxidant found in Tomatoes, Watermelons, Melons andApricots, seems to be the most effective carotenoid to eliminate reactive oxygen molecules (freeradicals). Differently from what is generally thought, it offers better protection against ultravioletrays than Beta-carotene, even though the latter is present in the same amount ( 1225 ).An example of ageing interruption is given by retina macular degeneration, which can be slowed oreven stopped by assuming caretenoids such as Luteine and Zeaxanthin ( 1246 ).252

Other ageing factorsThe Epiphysis is deemed to be the body’s biological clock as it produces Melatonin and maybeother hormones. It is known that during ageing the Epiphysis is no longer able to stimulate theThymus, one of the most sensitive organs.It is also known that up to 30-40 years the body vessel endothelium can still produce enoughamounts of nitric monoxide (NO) from a complex mechanism of enzymatic reactions which beginswith a non-essential amino acid called Citrulline. This one is found in particular plants, some ofwhich are traditionally called “immortality plants” or “plants of eternal youth”.Hypercholesterolemia, on the other hand, reduces the amount of nitric monoxide (nitric oxide), butthis process can be reversed by lowering lipid blood concentration ( 1226, 1236 ).The nitric monoxide molecule seems to be the real “secret” of certain blue pills which are wellknown among not so young men…In addition to nitric monoxide, vessel endothelium produces other substances which are essential tohuman physiology; among these, of special interest is Somatostatin.Vessel endothelium degeneration, considered as the main cause of ageing, could be explained, asalready happened in the past, with a deficiency of vitamin C and other vitamins – e.g. E –preventing cholesterol plaques on the delicate cerebral arteries and protecting the body fromassociated damages to the Organula in Organu, first of all to the Epiphysis.Numerous studies about this theme have been conducted. The following is a report of someinteresting peculiarities: the positive effects of wine on Alzheimer ( 721 ), those of Ginkgo biloba oncataract ( 1217 ) or Lou Gehrig’s disease ( 722 ), the beneficial effects of Plants of the CrassulaceaeFamily (Orostachys japonicus) on hypothalamic neurons ( 1218 ) …253

Chap. 13.2.: Cardiovascular DiseasesThe etiology of cardiovascular diseases is obviously multifactorial, including coronary failure, mostcommonly associated to infarct. However, significant data show that oxidative stress is one of themain causes of this disease ( 1231, 1234 ).Low density lipoproteins (LDLs) suffer from the negative effects of oxidative stress if they are notprotected by antioxidants: LDLs are converted into peroxides by Homocysteine thiolactone, a cycliccompound deriving from the natural self-oxidation of Homocysteine.If nitric oxide and other serum antioxidants, such as Glutathione and ascorbic acid (vitamin C), aredestroyed by oxidative stress, then endothelial damages, proliferation of smooth muscle cells andperoxidation of LDLs are likely to occur ( 1227 ).Inside each LDL macromolecule there are 1,700 cholesterol esters and 700 free cholesterolmolecules, in addition to 6 tocopherol (SEE vitamin E) and other liposoluble carotenoids such astocopherol (vitamin E). These antioxidants protect LDLs from oxidative damages deriving fromlipid peroxidation, which can occur only when there is no more serum tocopherol. However,damage accelerates, then increasing in a linear way until there are no more liposoluble antioxidants.An increase of tocopherol extends protection for LDLs even though, in this case, carotenoids areless effective. Vitamin C rebuilds LDL surface tocopherol ( 1223, 1224, 1232, 1233 ).As the two Nobel Prize winners Goldstein and Brown demonstrated, cells normally absorb LDLparticles, one at a time, through a receptor-mediated endocytosis. After the peroxidation, however,LDL macromolecules become aggregates of foreign bodies which are phagocytized by endothelialmacrophages creating large concentrations of foam cells. Once dead, they produce cell detritus andtoxic lipid substances which are concentrated in the centre of an evolutive lesion of the vessel wall,called “vulnerable plaque”.In the microenvironment of these endothelial plaques there are numerous agents that can lead tocoagulation and inflammation. The rupture of this vulnerable plaque can cause, in some cases,1225, 1227, 1228, 1230,coronary thrombosis together with possible infarct and/or sudden cardiac death (1235 ).In her book, The Gerson Therapy ( 749 ), chapter 17, Charlotte Gerson writes: “…differently fromwhat Official Medicine teaches and believes, the composition and the development of atheromatousplaques in a patient on Gerson diet are not irreversible but reversible; so it is possible to cleanartery walls.” To reach this objective, many vitamins such as C and E play an important role.There are a number of scientific studies ( 1281, 1282 ) concerning medicinal properties of vitamin E andof proto-anthocyanidins which protect vascular endotheliums and heart respectively.254

Chap. 13.3.: Emergency MedicineIt is important to underline that in the context of emergency medicine oxidative stress reaches thehighest level causing patient’s most severe pathological conditions ( 1250 ) and leading to a seriousvitamin deficiency: most patients receiving Complete Parenteral Feeding in intensive care aregenerally given phials containing no more than a dozen vitamins and in some hospitals even muchlower amounts (1248) because of costs and availability. In other words, among thousands of naturalvitamins, whose beneficial effects are known or foreseeable, patients are given only some vitaminsand often in much lower amounts compared to the daily intake recommended for healthy people(RDA).It is thought that patients in intensive care with high if not maximal oxidative stress have not evenenough antioxidants to cope with normal circumstances. Some studies have recently examinedoxidative stresses showing potential benefits of antioxidants in some diseases such as septic shockand acute respiratory failure ( 1238, 1249 ).Oxidative stress and lipid peroxidation associated to Complete Parenteral Feeding have beendemonstrated ( 1245 ). A greater attention to natural vitamin therapies is therefore necessary ( 1247 ).Furthermore, oxidative stress and antioxidant therapy should become common practice inEMERGENCY MEDICINE ( 1251 ).For example, it should be normal to administrate endovenously TEN grams of vitamin C every 12hours to all patients hospitalized because of car crashes, work accidents, infarct, ictus, etc (seewww.laleva.orgYourself”, pages 194 to 197, by Andrei W.Saul)SEE Other: http://orthomolecular.org/library/jom/2000/pdf/2000-v15n04-p201.pdf )“How to give endovenously vitamin C to hospitalized patients”, taken from the book “Doctor255

Chap. 13.4.: The Failure of the Cronos Study on AlzheimerThe Cronos Study was conducted in Italy and was the most extensive survey ever carried outconcerning negative and positive results of treatments using ACETYL-CHOLINESTERASEINHIBITORS, i.e. Donepezil, Rivastigmine and Galantamine.The data were collected from 5,500 analysed Italian patients.In 2005, “L’Espresso”, an Italian newspaper, wrote: “After 9 months, among those who havecontinued the study, only one patient out of six has significantly improved… All efforts to find acurative and not a palliative treatment have come to a stalemate… Furthermore, among elderlydementia patients, cases of ictus triple and the death rate doubles…”.However, according to medical books, autopsies performed on patients who died of Alzheimershow high concentrations of Aluminium in basal ganglions ( 1289 ); besides, Fluorine has recentlybeen thought to be another silent killer leading to this disease.Detailed studies dealing with all possible alternatives to the current failure of drugs againstAlzheimer’s disease are scarce and difficult to find, given the lack of scientific rigour.Using antioxidants to protect and heal delicate vessel endotheliums and to eliminate toxicsubstances which could accumulate in the brain is obviously the safest solution. Some studies reallydemonstrate the positive effects of antioxidants on the course of the illness. This result will deservea more and more in-depth discussion about the use of natural vitamins to treat this disease too.Compared to healthy people, very low amounts of Vitamin A and D, Lycopene and beta-Carotenewere observed in patients suffering from Alzheimer’s disease.In particular, vitamin C deficiency was deemed to be the main factor leading to the disease, first ofall in connection with patient’s cognitive functions (cognitive impairment). About this point,Riviere’s accurate study is reported ( 1219 ). Moreover, in a study conducted on 633 patients aged over65 years, a diet rich in vitamin C proved to decrease the risk of developing the disease ( 1220 ). Otherpromising vitamins are organic Selenium, Coenzyme Q10 and, above all, Magnesium.Going back to acetyl-cholinesterase inhibitors, it was observed that Huperzia serrata does not havethe same side effects as Prostigmina, Tacrina and Donepezil, even though it is an effective acetylcholinesteraseinhibitor allowing significant improvements of memory, cognitive functions andbehaviour in more than half of the cases ( 1341 ). Note should be taken of interesting results obtainedusing DHEA ( 1342-1343 ) and Ginkgo biloba ( 1344-1347 ). This one was found to stabilize the disease andto improve mental functionality in 64% of cases with no side effects. Ginkgo biloba must be takenfor at least 4 months, though.See Alzheimer (OTHER): http://fiocco59.altervista.org/nacci/alzheimer-therapy.pdf256

Chap. 13.5.:The common fallacy that cholesterol is bad, the truth about vitamin Cdeficiency and the pharmaceutical issue of StatinsAs far as cholesterol is concerned, what follows should be carefully considered. In universities it isstill taught that the main cause of infarcts and cerebral strokes is the high cholesterol level in thebody. If it were true that high amounts of cholesterol in the blood really damage blood vessel walls,they should harm not only heart and brain but every part of the circulatory system. In other words,that would lead not only to myocardial infarction (of the heart) or cerebral infarct (of the brain) butalso to infarcts of nose, ears, knees, elbows, fingers, liver, bones, etc.But this never occurs.Furthermore, vitamin C deficiency in humans and monkeys should receive the proper attention.Differently from almost all other animals, humans and monkeys are not able to produce vitamin C.This explains their predisposition to vascular diseases such as myocardial infarction and strokes.So the human body tends to compensate for vitamin C deficiency with cholesterol on connectivetissues lacking in this vitamin.The lack of vitamin C in today’s diet forces the patient’s body to use cholesterol to “keep together”tissue collagen fibres, thus endangering some delicate “strain” areas such as arterial walls whichtend to form atheromatous plaques. According to scientific literature, these plaques can regress ifvery high amounts of vitamin C and other vitamins are taken.The threat of statinsLipobay and other statins eliminate cholesterol from the human body in an innatural way, thuscausing ruptures of important arterial walls as their “glue” (cholesterol or enough vitamin C) ismissing.Please note that a sudden and innatural lack of cholesterol in the human body could also lead toother diseases such as Multiple Sclerosis (study on a clinical case, SEE Chap. 11).Commercial interest in developing statinsA scientific study analysed 163 articles from medical journals concerning the use of statins. It foundthat some authors can be accused of conniving with the pharmaceutical industry.According to an article published by Medical News Today, more than 36 million Americans takecholesterol-lowering drugs. Experts state that following the new “guidelines” for the treatment ofhigh cholesterol (SEE “Statins”), that figure will increase by 7 million. The turnover of these drugsamounted to 26 billion dollars already in 2003.257

Chap. 14:Scientific bases of an ANTI-CANCER therapy on a dietary andmultivitaminic basisThe basic reason which led the author to a therapeutic approach to a real ‘Anti-cancer Diet’integrating more than 400 medicinal plants (to be more specific, SEE attached “Basic Protocol,Nacci Therapy”), was fundamentally due to a reflection on the many schools of medical thoughtwhich have arisen to find a cure for cancer. The most important, all based on thousands of activefactors extracted from medicinal plants (SEE also The Ninth Declaration of Intent) are: traditionalChinese medicine (Pen Tsao), traditional Indian medicine (Ayurveda) and classic Westernmedicine. The latter, in particular, is described today in different protocols such as the “Gersondiet”, the “Breuss diet”, the “Hoxsey therapy”, and other authors (Maria Treben, Renè Caissè, J.Valnet, Castore Durante etc.). There are, in fact, private clinics which follow these ‘classic’Western therapies (Classic Phyto-therapy Medicine’), often combined with Indian and Chineseformulas.Gerson Institute:http://gerson-research.org/docs/GersonM-1949-1/index.htmlhttp://gerson-research.org/docs/GersonM-1945-1/index.htmlhttp://gerson-research.org/docs/GersonM-1878-1/index.htmlhttp://gerson-research.org/docs/CapeFW-1978-1/index.htmlhttp://gerson-research.org/docs/HaughtJ-1962-1/index.htmlPersonally speaking, the author maintains that the common denominator for the therapeutic successof all these European, American and Asiatic schools lies essentially in the fact that the nutritiongiven to cancer patients is completely without vitamin B12, almost without glucose, without nucleicacids (DNA), and without the foods which contain all 9 essential amino acids (Leucine, Valine,Isoleucine, Lysine, Methionine, Trypthophan, Threonine, Phenylalaine and Histidine).On the contrary, the phyto-therapy nutrition described here will be rich in tens of thousands ofvitamins and pro-vitamin compounds, able to detoxify organs and emunctory systems (gastrointestinalsystem, liver and kidneys, SEE chapters 3, 4 and 5), causing the phenomenon of apoptosisin the cancer cells (SEE chapter 6), that is by inducing a reactivation of the endonuclease enzymes,so that the DNA of the cancer cells self-destructs. What is more, it sets off the immune cascade(SEE chapter 4), that is, it induces the reactivation of the Natural Killer lymphocytes, of Blymphocytes (with the production of polyclonal antibodies directed towards the tumor-associatedanti-genes of the diseased cells), and of Killer lymphocytes, thus reaching the full immune cascade(activation of monocytes, granulocytes etc…).To complete the therapy thus described, it is also important that the patient follows a moderateexercise routine so that the organism does not consume its own muscular mass in order to satisfythe biochemical request from the tumor for vitamin B12, and from the cancer cells for nucleic acids.It is important for the patient to be instructed in and followed throughout the therapy, together withthe members of his family, because everyone should be aware of the methods of the treatment, andmost of all of the particular diet that the patient must follow during the long period of therapy.NB: The doctor in charge can choose the medicines based on chemical synthesis which can be usedwith the Phyto-therapy, according to his clinical and laboratory evaluations.The anti-neoplastic therapy, as carried out by the doctor in charge, must be based on the followingthree-point therapy:258

1) use of plants for medical purposes ( Aloe arborescens, vitamins A,C,E,F, Germanium, B17)2) anti-cancer diet (SEE Chap. 2)3) continual physical activity, in order not to deplete the patient’s system of its muscularproteins, since the cancer cells are “starved” by the diet followed, with the result that theorganism’s metabolic system searches for the following organic tissues for endogenousnutrition purposes:a) the patient’s own muscular tissueb) adipose and reserve tissuec) the neoplastic tissue itself (as observed by the author)On the basis of personal observations, effective recovery from the tumor, even if it is veryextensive, could depend on:Physical activity 50%Anti-cancer diet 30%Medicinal plants 20%According to the author, we should therefore give importance to food which is free of, or at leastlow in nucleic acids, proteins, folic acids and vitamin B12: the main reason for this is that thetumor only grows because of particular energy giving factors (glucose) and substances necessaryfor the synthesis of new DNA for the creation of new tumoral cells (cellular mitosis). Following thediet, the low quantity of glucose and the reduction in or even absence of nucleic acids, proteins,folic acids and vitamin B12 will tend to block the tumoral growth. But because the organism cannotsurvive without these substances, there will also be a constant depletion of these substances fromthe muscular and adipose tissues: it can therefore be deduced that the neoplastic tissue will also bedepleted.In other words, the patient will begin to "feed himself" with his own cancer. Thus the need tointegrate the pancreatic enzymes with similar ones of vegetable origin, with the purpose of helpingthe organism in this process of organic depletion at the tumor's expense.It is also important not to eat pasta (or polenta, or rice, or bread) together with pulses, because doingso there is an integration of the 9 essential amino-acids (the 8 contained in the cereals + the 8contained in the pulses), with a nutritional effect similar to the one obtained by eating meat, fisch,ham, eggs, milk, cheese…Basically, it consists of a diet rich in fresh fruit of the season and fresh vegetables (from 10 to 15portions a day of each);Cereals should be taken in adequate quantities (small portions), and only in case of proven necessity(fever, excessive weight loss). Fruit and spices are also very important.Food must be of a good quality, possibly bought from organic farms, or at least free of anydangerous chemical additives.There should also be particular care in the consumption of natural vitamins.Attention must be paid to exotic fruit, or fruit and vegetables which come from regions wherehealth and hygiene are not well controlled, could be carriers of infectious diseases because of thedirty waters (sometimes, even liquid sewage) used to irrigate the land.Fish should be eaten only after the immunity cascade has begun, with a noticeable dimensionaldecrease in the tumoral mass, given the possibility that the essential amino-acids found in fish couldbe assimilated by the tumoral cells as well.259

There should also be particular care in the consumption of natural vitamins (SEE chapter 3).We strongly advise against the administration of Saccharomyces cerevisiae, because of the highquantities of folic acids and nucleic acids, even though this substance is also very rich in usefulvitamins and minerals.It will have been noticed that there is a complete exclusion of sugars, except fructose. This isbecause the latter contains a low glycemic level: it therefore behaves differently from all the othersugars (glucose, saccharose, mannose, etc...) because it is absorbed slowly in the intestine; from theblood it then passes directly to the liver, where it is turned into hepatic glycogen. This course avoidsa dangerous hematic hyperglycemia which, even if transitory in the non-diabetic neoplastic patient,gives an energy contribution to the tumoral cells.The particular greed in accumulating glucose that the tumoral cells seem to have is exploited forexample in diagnostics. In fact, in Nuclear Medicine is it now a consolidated practice to markparticular molecules of glucose with a particular radioactive tracer (Fluoride 18), for the precisepurpose of spotting tumoral masses through these sugar molecules.In fact, the fluorine18-glucose localizes itself on any kind of neoplastic mass. However, it should benoted that the glucose is gathered electively also by particularly sophisticated organs such as theheart and the brain.After 50-70 days of diet-therapy (under medical judgment), the diet should also be moderate in theconsumption of pasta or wholemeal polenta (if organic Zea mays), while the following cereals areallowed: Hordeum volgare (barley), Milium effusum (millet), Triticum spelta (spelt), Oryza sativa (rice), Triticum durum (wheat) and Triticum aestivum or vulgare (soft wheat).Note 1: Avena sativa (oats), is questionable for Auxina and Lisin.Note 2: Helianthus annus (sunflower seeds) has Methionine: not eat with pulses.Note 3: pulses as Glycine maxima or soya (soya), Phaseolus vulgaris (beans), Canavalinaensiformis (Mexican beans), Fagopyrum esculentum (buckwheat or black wheat), should beavoided, because they are too rich in proteins and /or for Lisin and/or Tryptophane.Note 4: Glycine maxima or soya (soya), Zea mays (sweet corn, maize), Phaseolus vulgaris (beans),Nota 5: Oryza sativa (rice) and Solanum tuberosum (potatoes) should be avoided, because they aretoo transgenics (all the 9 essential amino-acid).Nota 6: Secale cereale (rye) and Amaranthus hypochondriacus (amaranth) are too rich in Lisin.Nota 7: Fagopyrum esculentum (Buckwheat) is not a cereal, it is a pulse because it belongs to thePolygonaceae family; unlike the graminaceous plants it is rich in Lysine, it should therefore not beeaten together with them.After 80-300 days of diet-therapy (under medical judgment) a moderate diet of salt-water fish (notfarmed fish, but small-sized fish, and never fried); fish-oil (omega 3), tuna fish is allowed (eventhough it is large);Note 1 : perhaps also bread is danger (for vitamin B12 and transgenic risk of the meal).Note 2: Cotton oil should also be eliminated, because it accumulates high percentages of herbicidesand pesticides.Another notes:1) it would be preferable to start eating fish only after the immunity cascade has been induced; this also appliesto other foods rich in protein, folic acid, vitamin B12, nucleic acids such as white meat, eggs, milk, cheese,liver, or royal jelly, but it’s danger.2) Honey must not be taken to give energy, but only as to help the transportation through the gastro-intestinalsystem of the active principles contained in Aloe and in the seeds and sprouts (about 250 recognized species),which are taken for anti-neoplastic purposes (SEE chapter 5: apoptosis).260

3) Indian Ghee is still under evaluation (it is a clarified, deproteined and dehydrated butter, containing importantactive principles such as butyric and linoleic acid, liposoluble vitamins and many more ).4) Wild Barley (Hordeum volgare) is still under evaluation”. Green Barley shoots are surely prohibited (itcontains vitamin B12, folic acid and up to 8 essential amino acids, including Lysine and Methionine; it lacks inTryptophan).5) wheat germ oil is still under evaluation.6) Soya lecithin is still under evaluation (possible anti-tumoral induction, but today it’s all transgenic Soya).7) Sesamum indicum (Sesame) oil is still under evaluation, for the consumption of mixed seeds following the oldIndian tradition: it is the most widely used oil in Ayurvedic tradition, because it absorbs the various propertiesof the herbs which are used in Indian medicine very well, thus allowing good passage through the gastrointestinalsystem; this particular oil should be cold pressed. On the other hand, it has a high percentage ofprotein components (25%), and therefore its use needs to be evaluated.8) The use of algae is still under evaluation, because their use is debatable: for example Spirulina, widely used invegetarian diets, cannot be equaled by any other element as to the quantity of proteins contained: from 60 to70% in dry weight compared to 45% in dried eggs, 40% in Glycine maxima or soya (soya), 20% in meat;Spirulina is also the richest natural source of vitamin B12, the contents of which are 250 times higher than inliver. On the other hand, the blue algae found in the North-American lake of Klamath is particularly interestingbecause it can induce a specific immunity response against tumors (Immunity Cascade) even at low dosage (1-2 grams), but it’s rich of vitamin B12.9) Are under study another particular foods ( 1149-1153 ).In the meantime, the Immunity Cascade (SEE chapter 9) may need to integrate the nucleic acids, theessential amino-acids, folic acid and vitamin B12 (already absorbed at the tumor's expense) with afurther exogenous addition (external, in other words deriving from food), with the purpose ofsynthesizing a higher number of cytotoxic lymphocytes T, Natural Killer, Killer, Monocytes-Macrophages: thus the possibility of integrating the diet with supplements of these activeprinciples, without going beyond certain values (fresh fish: quantities still to be determined; perhapsalgae and bread; not meat, ham, eggs, milk, cheese, liver).Such supplements should be started a couple months after the patient has been following the diet,with hematic tests able to prove that the immunity cascade has taken place, and with an X-Rayshowing a tumoral mass which is reduced compared to before: if the tumor is still characterized bya considerable cancerous mass, and of a certain size, it would be advisable to still not administersuch substances, leaving the organism to continue “feeding” itself with the tumoral mass. Anexcessive (and unbalanced) loss of weight in the patient and the hematic indicators of the levels ofAlbumin, are the simplest factors to observe to understand the effective level of "depletion" inducedon the patient's healthy tissues, therefore allowing to evaluate whether or not to give externalsubstances which are potentially dangerous such as royal jelly or fish (because of the quantities ofnucleic acids, essential amino-acids, folic acids, vitamin B12).According to the author, the diet should be based on 12-15 daily portions of fresh vegetables, freshfruit, apple vinegar, flax oil (vitamin F), italian extravergine oil, with the addition of 14-18tablespoons of Aloe arborescens (2 tablespoons every 2-3 hours), Potassium Iodure, 9-15 grams/day of natural vitamin C (SEE chapter 3), Magnesium, Zincum, Omega-3, vitamin B17 (SEEchapter 7), Ananas sativus stalk (chapter 3), Allium sativum and Allium cepa for organicGermanium 132, (SEE chapter 3), and then with the association of 20-40 medicals plants whichhave apoptotic activity for the particular type of neoplasia which is occurring (SEE chapter 6 and9).Cereals should be taken in adequate quantities (small portions), and only in case of proven necessity(fever, excessive weight loss).261

Using energizing substances to sustain the increased pyretic metabolism(temperature)The temperature induced by the Immune Cascade consumes high quantities of energy: this canbring about a reduction both in the cancer mass (positive effect) and in muscular mass (negativeeffect).It is therefore important to remember that it is necessary to keep the patient’s weight loss and thehematic values of the albumenemia continually under clinical observation, and follow two basictherapeutic principles:1) physical activity by the patient, so as to reduce as much as possible the loss of muscle mass.2) to administer, in the diet, energizing substances which are not dangerous. These aresubstantially: fresh fruit, cereals and pulses.1 liter of liquidized fresh fruit (grapes, fruits of the forest) contains about 800-900 kilocalories,equal to 750cc of milk, or 650 grams of meat or 10 eggs….Even the fresh fruit which we have is rich in energy:1 liter of juice from biologically grown apples is 500 kilocalories1 liter of juice from biologically grown cherries is 450 kilocalories1 liter of juice from biologically grown pears is 420 kilocalories1 liter of juice from biologically grown oranges is 400 kilocalories.Never mix cereals and pulses at the same meal, because of the risk of adding together all theessential amino acids (which has a similar effect to eating meat, eggs, fish, cheese …..).Among the various cereals the following merit attention: Hordeum volgare (barley), Miliumeffusum (millet), Triticum spelta (spelt), organic rice and organic wheat (Triticum spelta andTriticum durum).American and European maize, American and European rice, American wheat must be discountedbecause they have been genetically modified (transgenic) and made toxic (maize).Glycine maxima or soya (Soya) must also be discounted because it is transgenic and has a highprotein content.The cereals should not be used in the form of grains or flakes because of the elevated glycemiccurve which would ensue in the blood; they should be eaten only as flour, or as shoots mixed withhoney (SEE chapter 5): because of this last fact it is worth noting the extreme importance of eatinggrain shoots rather then simple seeds.It is extremely important that the cereals are wholemeal.Flour is obviously the primary material used in pasta, bread (without yeast) and polenta.In the past Plus was famous; this was polenta made with Triticum spelta (spelt), Hordeum volgare(barley) and Fagopyrum esculentum (buckwheat) served with vegetables, Allium cepa (onions) andAllium sativum (garlic). But Fagopyrum esculentum (buckwheat) can no longer be used in our casebecause it is rich in Lysine, like many pulse vegetables, and it therefore has the possible risk ofbringing together all 9 essential amino acids at the same time.Wheat is the most widespread cereal: glutine, contained in its seeds in ideal proportions, renders itparticularly suitable for leavening and bread making. There are two varieties: durum wheat262

(Triticum durum) and soft wheat (Triticum aestivum or vulgare); the percentage of protein is about13% (Triticum vulgare) and 12.5% (Triticum durum).With the introduction of steel grinding stones rather than the traditional stone ones, there has been ahuge increase in the production of white flour, that is refined, which has kept the energetic value butnot the nutritional one (vitamins), because it does not have the external layer of the grains (the bran)or the grain shoots (vitamin E, SEE chapter 3.e).Very often attempts are made to add the bran to the white flour, but the resulting product bears noresemblance to real wholemeal flour: real wholemeal flour is a uniform amber color, the mixedversion is easily recognizable because it has a base which is dotted with brown bits, of either a lightor dark color.Other cereals: rice (6% protein), Milium effusum (millet, 11% protein), Hordeum volgare (barley,11% protein), Zea mays (maize, 9.5% protein), Triticum spelta (spelt, 12% protein).Buckwheat or black wheat (Fagopyrum esculentum) is not a cereal; unlike the latter it is rich inLysine and Tryptophane; it contains a lot of Iron, Magnesium and group B vitamins; (11% protein).It should not be eaten with cereals or potatoes because of the risk of consuming all nine essentialamino acids at the same time.In the blood, Triticum spelta (spelt) does not have a high glycemic curve, unlike other cereals, and itcan therefore be eaten by cancer patients because high peaks in the glycemic curve must beavoided.Amaranthus hypocondriacus (amaranth) and Secale cereale (rye) must be eliminated completelyfrom a cancer patient’s diet not only because of its high protein levels (16%) but also because itcontains Lysine, an essential amino acid almost completely absent from other cereals, because therewould be the possible risk of consuming all nine essential amino acids at the same time ifAmaranthus hypocondriacus (amaranth) were eaten at the same time as other cereals, above allwheat or maize (even if they are not transgenic):N.B: wholewheat pasta (Triticum spelta, Hordeum volgare etc…) being whole, contain a lot ofstarch, so that, compared to pasta made with durum wheat, they should be drained well. They havea richer flavor than white pasta and so as not to lose this by draining the pasta it is better to put asidethe water used for cooking the pasta to use in a vegetable soup. Cook the vegetables in some of thepasta water with half a stock cube, then liquidize to obtain a creamy mixture. There are various foodcompounds on the market which try to include these cereals in the diet. Wholemeal flour should beused, with no additives.The patient must be treated according to the laboratory values obtained from blood tests, checkingany possible improvement in his/her clinical condition, with a reduction in pain or vice versa theonset of temperature (ideally this should be at 38-38.5 degrees Celsius, and must not go higher than39).Particular attention must be paid to the improvement in the transminases, the creatinemia, thelymphocytic fraction, the increase in uric acid (SEE chap.4-5), the VES and other inflammatoryrates. The cancer markers must be evaluated case by case (SEE chap 14.1). For some cancermarkers in particular, for example CEA, PSA, CA19.9 CA125 or beta2microglobulinemia, hematicincreases higher than Cut off must be noted, once the full anti-neoplastic immunitary response isreached, with a parallel increase in uric acid, with a subsequent recovery from the disease and hencea subsequent spontaneous lowering of hematic values of these particular markers.263

Chap. 14.1:Clinical Aspects, Instrumental Data and Laboratory Values/ResultsUpon observation of over 50 patients, the evolving process of Immunity Cascade (Wave) inducedby Aloe arborescens and other herbal remedies, in addition to the modified Gerson Therapy (i.e. theAnti-cancer diet of the author of this article) seems to be the following:The patient's psychological approach to the illness is also important ( 591-594 ), which only a gooddaily relationship, medical treatment and family help can give, avoiding any conflicting medicalopinions on the choice of therapy, at least in the presence of the patient himself.It is particularly up to the Doctor in charge to impose the anti-tumoral diet, visiting the patient athome, varying the diet with the help of the family and organizing any lab tests which are consideredappropriate and, if necessary, organizing any drug therapy at home.Letters of 14 patients are on INTERNET : http://www.mednat.org/cancro/Casi%20clinici.pdf18 Clinical Cases (Italian language) : www.mednat.org/cancro/Casi%20clinici.pdf orhttp://www.aloearborescens.tripod.com/18-casi-clinici-terapia-metabolica.pdfUpon observation of over 50 patients, the evolving process of Immunity Cascade (Wave) inducedby Aloe arborescens and other herbal remedies, in addition to the modified Gerson Therapy (i.e. theAnti-cancer diet of the author of this article) seems to be the following:INFLAMMATIO LYMPHONODIS (Inflammation of the lymph nodes):This is the inflammation of only the lymph nodes in proximity of the tumour, due to the activationof the Natural Killer lymphocytes. These lymph nodes will appear “reactive” during eventual scans.Immunity Cascade (Wave) against cancer (Immunity Response) always starts at lymph node levelwhere lymphocyte natural killers are present. These lymph nodes are always located close to thearea of the tumour, due to the continuous lymphatic drainage (lymphatic circulation) that drawstowards these lymph nodes (in actual fact a filter system network), possible tumour cells that comefrom organs or tissues near the lymph node itself.As already reported in medical literature (e.g.: V. H. Engelhard: “Science”, n.314, october 1994;John Ding-E Young and Zanvil A. Cohn, “Science” 1994 ” ( 1266, 1267 ) in Italian language :http://www.mednat.org/cancro/Le%20Scienze%201994_%20Natural%20Killer.pdf ) the tumour cell is thus“examined” inside the lymph node by these and other particular lymphocytes, that analyse itsgenetic features made up of thin protein strands that are present on the surface of all cells bothhealthy and non. If the genetic feature is altered in its sequence, something rather common in thecase of cancer cells, these lymphocytes kill the cancer cell through the use of a particular proteinneedle (Perforine), by means of which they puncture the “foreign” cell wall, causing the loss ofPotassium and other substances contained within. Once it is killed, the tumour cell is analyzed andprocessed in this particular and absolutely precious biological micro-laboratory.According to the author of this work the lymph node would thus mature (and develop), in the courseof the following days and weeks, its immunitary response to Cancer. Therefore this immunitaryresponse substantially gives way to a swelling of the lymph node, that can even reach the size of afew centimetres. These lymph nodes are always “reactive” upon eco scan (i.e. they are notdestroyed in their internal morphology by the neoplasm invasion, but they only appear enlarged insize) and therefore SHOULD NEVER be removed. When surgeons, on the other hand, removethese lymph nodes, their result is nearly always negative and hardly ever present tumour cellssometimes only small infiltrations of tumour cells can be traced. (Note: though some of them result264

to be totally overthrown in their morphological structure, being completely invaded by tumourcells).The majority of lymph nodes, however, appear healthy and “reactive” to the tumour but, when theyare removed by the surgeon, the local immunity response fails to take place. As a consequence, thetumour could, at this point, spread after a while to other areas that are rather distant from where itprimarily originated (metastasis), for the very fact of the lack of filter action that these veryimportant “network systems” have. Radio-Therapy also produces, strangely enough, a negativeeffect in the Immunity Cascade (Wave) process, because very often heavy session affect also theprecious lymph nodes located in the vicinity of the primary tumour.A patient with documented cancer in the right breast (who had undergone neither Surgery, norRadiotherapy, nor Chemotherapy nor Hormone Therapy), after 48 months of this NACCI-therapy,started to present a swelling in the lymphnodes of the right arm-pit. Eco-scans revealed however,that the lymphnodes were “oval-shaped and reactive” due to immune response. At present thepatient is in good health conditions.The Immunity Cascade (Immunity Response) remains local per many months. This makes theinitial therapeutic approach extremely delicate because it must safeguard first of all the “reactivelymph node”, where very few Natural Killer Lymphocytes have finally recognized the illness. Onlyafter the complex phenomena of “Immunity Cascade”, i.e. of the activated sequence of the GammaDelta Lymphocytes, Cytotoxic T Lymphocytes, B Lymphocytes, Killer Lymphocytes, Monocytes,will there finally be an Immunity Response that will not be local any longer, but finally generalizedand widespread throughout the entire immunity network of the patient (production of Interleukin 6(SEE C-Reactive Protein), activation of B Lymphocytes, presence of the Polyclonal Antibodies).INFLAMMATIO TUMORIS:This is characterized by Dolor, Calor, Tumor, Funcio lesa, in the area of the body hit by Cancer.There may also be temperature (always and however in the afternoon and/or evening). The pain(dolor) caused by Inflammatio tumoris seems to be different from cancer pain. Pain due toInflammatio tumoris is generally experienced with Immunity Response (Immunity Cascade), i.e.during the afternoon after 3.00-4.00 p.m., and is easily kept under control by simple antiinflammatorydrugs (NSAIDs). Vice versa, pain due to growth of Cancer (Dolor mali moris) can, inno way, be dominated, if only partially, and however for a limited length of time, throughChemotherapy, Radio-Therapy, Surgery, Cortisone, Opiates (drugs). Calor (heat) caused byInflammatio tumoris is also onset by the Immunity Response, i.e. in the afternoon, after 3.00-4.00p.m. and is eased by simple anti-inflammatory drugs (NSAIDs). If the tumour mass is consistent,the heat (Calor) will be similar to a fever. If the tumour is superficial, the inflammation will cause itgo soft (instead of hard) when touched, it will appear increased in size (approx. 1/3 of its originalmass), hot instead of cold and the skin will be red.It has been proved that properties contained in the essential oil of certain plants can actually inducecell death (apoptosis) (SEE Chapter 5) and are particularly effective on this type of tumour. Evenmetastases found in bone regions, like in the cervical, dorsal and lumbar vertebrae, react rathereffectively with this type of clinical-therapeutic approach.In particular, pure oil of Hypericum perforatum (produced on small-scale from fresh plants) hasbeen experimented on a dorsal metastasis consequent to liver carcinoma and Juniperus officinalisoil (also made from fresh plants and produced on small-scale) on diffused bone metastasis due tocarcinoma of the breast.In this latter case, it was possible to prove also the cranial-caudal behaviour in connection to the immunity response, ina patient with metastasis in the cranial region, the dorsal-lumbar rachis, the sternum and iliac wings. After graphing the265

dates that registered peaks of CA-15.3 in the blood test (coincident with phases of particular worsening of skeletalpain), what could be observed was that during an eight-month time span the Immunity Response, supported by localapplication of Juniperus officinalis oil, along the entire rachis, on the Iliac bones and on the sternum, continued its slowbut progressive cleansing action from top to bottom. This came about in cyclic surges, with a constant and gradualincrease of the circulating lymphocytes and VES. Thus, after eight months, this gave way to a gradual increase of theReactive C Protein.Many other patients with clinical cases of disseminated metastases to other organs and systems havealso presented this cranial-caudal response of the Immune System (confidential data).In the book “Gerson Therapy ”: …With all its defenses restored, the body is again capable ofdestroying tumor tissue, breaking it down and excreting it. The most aggressive kinds ofmalignancies (as melanomas, ovarian cancers, small-cell lung cancers, aggressive lymphomas)retreat the most rapidly. One can almost watch them melt away…(from: “The Gerson therapy. Theamazing juicing programme for cancer and other illnesses…”, by Charlotte Gerson and MortonWalker, Thorsons ed.; pp.30FUNCTIO LESA:In many cases the inflammation of the organ affected by cancer may, in many cases, to be putpartially or totally “out of order”. For example, in a woman patient with left lung cancer who hadnever undergone Surgery, Radio-Therapy or Chemo-Therapy, for 12 months her left lung presenteda total atelectasis, without any pain whatsoever or other particular phenomena that could worsenedthe patient’s condition. VES value was, however, rather good (50-60 mm first hour).DEPROTEINATIO TUMORISThe Anti-tumour Diet must not, as far as possible, contain any proteins: the latter for thefundamental reason that the growth of the tumour occurs, above all, through this particularnutritional factor. (Es. ” Hildebrand, G.L.: Five year survival rates of melanoma patients treated bydiet therapy after the manner of Gerson: a retrospective review, in Alternative Therapies, vol.1[4],September 1995, pp.29-37 http://fiocco59.altervista.org/27novembre.htm MELANOMA )www.gerson-research.org/docs/HildenbrandGLG-1996-1/index.html ).”As the body cannot survive without proteins, it will try to start up a mechanism of depriving themuscles and reserve tissues of these substances for the scope, above all, of nourishing the Cancer:the Proteolysis Inducing Factor (PIF) is produced directly by the tumour cells and is found in theblood stream. The PIF induces the destruction of the muscle proteins so as to nourish the verytumour cells with essential amino acids, vitamin B12 and folic acid. The PIF sets off the WastingSyndrome. But, it is believed that this impoverishment will also occur to the neoplasm tissue, if themuscle mass is not allowed to be demolished and can thus be toned up appropriately through dailyphysical exercise and with an intake of a consistent quantity of Omega 3 oil (this inhibits the PIF).This way the body is compelled to search for non-essential protein reserves, like fat deposits and,above all, the very tumour tissues: in other words the patient will start “nourishing” himself with hissame Cancer.The period of strict diet, with no blue fish, can vary from 3-4 months to over 10-12 months,according to the type of tumour, its metastases, age of the patient, general physical conditions,blood test reference values, etc. It is therefore the doctor’s task to decide the best moment, to take266

the big step towards introducing the first amount of this type of food (fish) which abounds in all 9essential amino acids, vitamin B12, folic acid, DNA.Vice versa in a patient with a serious metastasis in the liver originating from colon carcinoma, 12months after starting a therapy with Aloe arborescens and a diet of only fruit, vegetables and spelt(Triticum spelta), a protein diet (blue fish) was not yet prescribed owing to the fact that the patient,who was in good physical condition, maintained a constant level of Total Blood Protein (7-7,5grams/dl), VES value (20-36 mm first hour) during the first hour, Albumin within normal limitsand, a very interesting feature. The same vitamin B12 values were maintained at a low 150-200picograms/ml approx. 1 year after treatment began.As the patient presented two important tumour masses in the liver both measuring 5 by 7cm indiameter before therapy, it could be estimated that the tumour’s protein reserves, theoreticallystored away for the patient’s own nourishment, were enough for several months of survival becausethe tumour’s protein density was ten times higher than that of the healthy tissue. 12 months after thebeginning of the therapy, the masses in the liver appeared slightly reduced in diameter. There was asuspicion, however, that this was due above all to the protein density gradually diminishing ratherthan the size of the tumour itself reducing; a true sign of the presumed impoverishment of theprotein being drawn from the tumour. Note: the hepatic hilum lymph nodes are obviously“reactive”.RELIQUATIO TUMORISAfter following a totally non-protein diet and without Vitamin B 12 (SEE: “Chapter 14), the tumouris progressively deprived of all of its protein elements to end up as a Reliquatio tumoris, i.e. afibrous-necrotic tissue with no high level of protein density.After diagnostic investigations (X-ray Tomography, Magnetic Resonance Tomography), proteindensity loss would reveal a loss of the previous “high pressure of the interstitial fluid”, the latter istypical aspect of all malignant tumours. Therefore, there would be a loss of the previousaccumulation of contrast enhancement only around the peripheral margin of the tumour mass(peripheral “bordered” accumulations or “enhancement effect”).Traditional contrast enhancement for diagnostic–instrumental investigations was provided by :Iodine 127 when X-Ray Tomography (TAC) was used or Gadolinium 157 when MagneticResonance Tomography (MRT) was employed. The loss of “enhancement effect” should becorrelated to the previous loss of “high pressure of the interstitial fluid” of the tumour, i.e. to theaforementioned “high density protein of the tumour”, this time diagnostic instruments reveal anevidently good internal perfusion of the contrast (Iodine 127 with X-Ray Tomography andGadolinium 157 with MRT) throughout the entire tumour, therefore without having the “bordered”or “enhanced” accumulation outlining the tumour mass.This event of so-called “peripheral loss of accumulation” in contrast enhancement (loss ofenhancement effect) seems to come slightly before the final resolution (dissolution) of the tumourresidue, that may occur in several different ways: from the ”Expurgatio tumoris” (i.e. the expulsionof the fibrous-necrotic residue of the tumour), this can be total or partial, to the “Resolutio totalistumoris” (i.e. the re-absorption and complete digestion of the tumour residue), to the “Resolutiopartialis tumoris” (i.e. the presence of tumour residue in the tissues, mainly bone tissues), the latterseems to be a “bereavement” of fibrous-necrotic tissue that the body must, in time, totally eliminate(recorded clinical case). The final healing will occur through the process of “Restituito adintegrum” of the organs and systems previously invaded by Cancer.267

EXPURGATIO TUMORISThis is the expulsion of the fibrous-necrotic residue of the tumour (total or partial) that has beenobserved in various occasions. The following are some examples:First case: a foreign patient came to Trieste for a six-month cycle of treatment. The patientpresented a 6 cm x 3 cm tumour mass at the base of the tongue located mainly on the left side andbeing unable to eat solid food, could only swallow small amounts of liquid. Five months later, whenthe patient had to go back to work in his home country, the tumour mass had already diminished toless than half a centimetre (confirmation X-Ray Tomography and clinical-specialist investigationswere carried out before his departure). Note: 2-3 months after the beginning of the cure, i.e. 3-4months before leaving for his country of origin the patient “fistulated” a reddish-brown mass thesize of a little finger from the ear-drum of his left ear. It was not analysed and therefore it cannot beproved that it was part of the tumour. The suspected process of “Expurgatio tumoris” took threedays, and immediately after the patient was able to eat better and with less pain.Second case: A 13-year-old boy affected by Leukaemia. At present, (July 2007) at a year’s distancefrom the therapy started with Aloe arborescens and other herbs, the child is well and has had norelapse. His case of Leukaemia was overcome with the use of Aloe arborescens taken for only a fewmonths and was resolved with the elimination of the protein and fluid substance of suspectedReliquatio tumoris nature, through the lymph nodes of his armpit (April 2003), obviously with agreat deal of dismay on behalf of the child.RESOLUTIO PARTIALIS TUMORISThe storage of suspected tumour residue in the tissues, mainly in the bones. This seems to be a“confiscation” of fibrous-necrotic substance that the body must, gradually, completely get rid of.RISOLUTIO TOTALIS TUMORISThis phase substantially preludes the complete “RESOLUTIO AD INTEGRUM” of the tissues, theorgans and/or the systems previously affected by the tumour.268

OBSERVATIONSThe clinical and instrumental aspects concerning the patient (X-Ray Tomography, MagneticResonance, PET, Scans) are what the doctor is mostly engaged in. This compels him to delve deepinto his medical knowledge due to the complexity of the clinical situation. The following clinicaland/or instrumental and/or laboratory OBSERVATIONS can thus be outlined:VESAn increase in this value is attributed, according to the Gerson Institute, to a good immunityresponse against the tumour and therefore substantially to the body taking control.VES values equal to 40 mm first hour or over can be considered a good reference.Uric acid and UrineAfter the first few months when the consumption of meat, eggs, milk, cheese, butter, bread, pulses,mushrooms, algae and fish is strictly forbidden, once the immune cascade has started, a progressiveincrease of uric acid, of lymphocytes and of reactive C protein will be observed in the blood. At thesame time a decrease in high quantities of protein in the urine will be noticed, making the urine adark red color. The urine should be examined using reactive strips, which can be bought in thechemist’s, to make sure there is no blood in the urine. The patient should increase his/her normalintake of water, good quality water with no chlorine, and should follow nephro protector phytotherapy (SEE chap.5). This should be enough to keep the process of urinary discharge of theseproteins of possible cancer origin under control.TemperatureThe temperature always rises in the afternoon, at least in the initial phase, and does not react toantibiotics. The author of this work does not believe that this can be attributed to ANTI-CANCERIMMUNITARY CASCADE (IMMUNE RESPONSE) and therefore the administration of cortisoneor antibiotics can play a negative role in this process. In particular, modifications caused byantibiotics to the bacterial flora in the intestine that can lead to “intestinal dysbiosis” (e.g. high levelof EOSINOPHILS) could totally nullify the immunitary response.Scan “reactive” lymph nodesThe “reactive” lymph node must have the following characteristics:1) it must be oval i.e. it maintain a certain roundness in shape (the longitudinal diametermust be double the transversal one);2) it must not be too dark. The more “hypoecogenous” the more “suspect” it may turn outto be, in other words, it has either metastacized or it may be itself the source of neoplasm(Lymphoma);3) the Ilo must be recognizable (when lymph nodes are vascularized they are similar inappearance to the ramifications in the kidney).Note: sometimes by closely inspecting the vascularization, it is possible to observe theill portion inside the very lymph node (in this case a second -generation contrast enhancement likee.g. “Sonovue” can be utilized).269

NOTE : the healthy and reactive lymph nodes (not metastasis) is COLD underPositron Tomography with F-18 Desossiglucosethe metastatic lymph nodes (not healthy and reactive) is HOT under PositronTomography with F-18 DesossiglucoseAnother value of Blood:Carcino-embryonic antigen (CEA)False positives are often found following either post-operative inflammations, or other kinds ofinflammations.Cut off for non-smokers: 5 ng/mL. Cut off for smokers: 8 ng/mLAlpha Feto Protein (AFP)Its increase is also linked to the proliferation of normal hepatic cells, not only in the case ofprimitive or metastatic neoplasia of hepatic, testicular or ovarial derivation, and from a teratoma.Cutoff: 10 ng/mLTissue polypeptide antigen (TPA)It belongs to the cyto-keratins, which constitute the cyto-skeleton of epithelial cells. It is releasedinto the system because of the cytolythic phenomena of neoplasia. It can be found in tumors whichare situated in the gastro-enteric tract, or in the genital and urinary tracts, the breast, the lung andthe thyroid. It has a higher number of false positives than CEA, especially in the case of hepatitis,cholestasis, cirrhosis of the liver, infections of the respiratory tract and of the urinary ducts. The cutoff is estimated at around 60-80 U.I./L. Among the various cyto-keratins, the circulating cytokeratin19 (CYFRA 21.1) proved to be particularly useful for epidermal tumors of the lung (70%),adenocarcinomas of the lung (60%), and microcytomas (55%). Its hematic confirmation is alsopossible in patients with tumor of the breast, of the uterus, of the bladder and of the stomach.Tissue polypeptide specific (TPS)It is useful in case of breast tumors, tumors of the gastro-enteric system and of the genital area.According to various authors, the TPS parameter could be used with good results for the evaluationof the responses to the cyto-reducing therapy and as a prognosticator, because it is more specific inevaluating proliferating activity of the tumor.SCC Antigen (Squamous Cell Carcinoma antigen)It may be found in cutaneous, esophageal, pulmonary and cervical spino-cellular carcinomas. It mayalso be found in psoriasis, pemphigus, in eczemas and in other benign pathologies of the skin.CA 125:epitope found on a mucin linked to the coelomatic epithelium, in ovarial carcinomas (serous andmucinous). It also occurs in inflammatory situations on an aspecific base, for example ovarialendometriosis and inflammatory peritoneal reactions. Cut off: 35 U.I./mL.It is not considered valid to search for relapses in patients with a minimum residue of illness.CA 19.9It has been proposed as an elective marker for the screening and diagnosis of tumors of thepancreas, thanks to the fact that the effect of false positives is very limited, because of concurrentinflammatory illnesses (colitis, pancreatitis, intestinal polyps). Cut off of 37 U.I./mL. It is present in270

70% of pancreatic cancers, in 50-60% of stomach tumors, in 45-50% of neoplasias of the colonrectum,and in 40% of carcinomas of the biliary tracts.CA 50Wide-spectrum mucinic marker for tumors, can be superimposed on CEA and TPA. Also frequentlypresent in benign pathologies, and therefore characterized by a high level of false positives.CA 15.3Mucinic marker considered to be more specific than CEA and TPA. It is the marker chosen forbreast tumors, because there is a limited occurrence of false positives deriving from concurrentinflammatory illnesses (15%). Cut off: 37 U.I./mL. It is present in 33% of localized mammarytumors, and in 89% of metastasized ones. It is rare in other tumors (25%). It is useful in monitoringcyto-reductive treatments, because it has been proven that the positive or negative variations of thehematic concentration of this marker are associated with an increase or decrease in the mass of theneoplasia, especially if metastasized.Mucinous-like cancer antigen ( MCA )It is also considered elective for mammary tumors, since it produced by the secretion of the breastitself in normal conditions: it enters the systemic circulation only when the development of theneoplasia is such that it determines a subversion of the structure of the gland. It is therefore a goodindicator of the progression of the neoplastic illness and the monitoring of the cyto-reductivetreatments, with a low percentage of false positives (10%) and a positiveness related to the stage ofthe illness: 20-30% in case of a localized tumor; more than 60% in case of metastasis. Cut off: 12U.I./mL.CA 549Specific marker for mammary tumors, comparable for its specificity and sensibility to CA 15.3 andMCA. Cut off: 11 U.I./mL. It is present to a percentage of 10-15% during the first two stages ofneoplastic mammary illness, and then progressively increases to up to 40% during the third stage,finally establishing itself at 75% when the illness reaches the fourth phase.CA 195Specific marker for tumors of the pancreas and of the colon, it can be superimposed over CA 19.9due to its specificity and sensitivity; it is superior to CEA.TAG 72Wide-spectrum marker for tumors, it can be superimposed over CA 19.9. It is present in gastriccarcinomas from 40 to 64%, and in carcinomas of the colon from 55 to 67%.Vanilmandelic acid (VMA) and omoranillic acid (OVA)They are metabolites of the serous catecholamines, which increase 90% in the case ofpheocromocytoma and 70% in the case of neuroblasts. At present it is considered preferable tomeasure their values with reference to a milligram of creatine, considering the practical difficulty incollecting all the daily urine. In this way, the cut off values are as follows:VMA: 20 mg/ mg of creatineOVA: 40 mg/mg of creatineNB: patients should have been deprived of certain food, such as tea, coffee, chocolate, vanilla, andof medicines which based on sympathetic-mimetic amines and bronchodilator syrups.271

Specific prostatic antigen (PSA)Cut off: 2,5 ng/mL.C-Reactive proteinIt is related to the soluble receptor of Interleukin 6 (IL-6), and therefore to the tumoral growth ofMultiple Mieloma( 572, 575 ); the very same IL-6 is the major factor in allowing the survival ofMultiple Mieloma cells, because it inhibits apoptosis of the infected cells ( 573, 574 ).As regards all the other tumors, the immune cascade also determines a gradual increase in the C-reactive protein, related to the Interleukin 6 and therefore with B lymphocytes. Thus, theconfirmation in the immuno-electrophoresis of the hematic protein profile, the gradual increase thegamma globulins as well, which can reach very high levels, assuming the form of a real "PolyclonalPeak", unequivocal sign of the patient’s effective immunization against his own tumor.Hyper-CalcemiaIt can be caused not only by a tumor of the bone marrow, but also by a high anti-neoplastic immuneresponse (which is possible, in the absence of Chemo-Therapy), because both the tumoral necrosisfactor and the various Interleukins ( 124 ) determine a Calcium increase in the blood, with all theconsequent clinical characterizations (drowsiness, sleepiness, lack of appetite, nausea, polyuria,systolic increase of the systolic PAO...)Beta2-microglobulinIt does not properly represent the effective growth of the tumor, because it can also be induced bythe phlogistic processes triggered as an immune response against the tumor. It belongs to theantigens of hysto-compatibility. It is very aspecific, and consequently it determines high levels offalse positives, especially in cases of chronic illnesses concurring with the neoplasia.Beta Chorionic Gonadotropin (β-HCG)Marker for germinal tumors of the testicle (20% if seminoma, 50-70% if not seminoma), and forchorionic carcinoma.Calcitonin (CT):NB: monitoring the parafollicular cells of the thyroid.Lymphocytic profile ( SEE table )Table: Lymphocytic profilePan T-CD3Pan T-CD4T suppressor CD8Natural Killer CD 16Natural Killer CD 56Pan B CD 19Normal values57-80%; 820-1.840 cells/microlitre33-58%; 480-1.315 cells/microlitre17-37%; 250-790 cell/microlitre3-19%; 80-335 cells/microlitre3-13%; 80-220 cells/microlitre2-19%; 53-335 cells/microlitreD-Dimers:produced exclusively by the degradation of fibrin; insensitive to the presence of PDF and offibrin. Good markers of the pre-thrombotic phase.272

Myoglobin:protein of muscular origin, the appearance of which in blood or in urine is a sign of destruction ofthe muscular tissues; it also reveals the state of the muscles and a situation of malnutrition.Retinol binding protein (RBP):situation of possible denutrition; however it increases in case of chronic kidney failure.Pre-Albumin:situation of possible denutrition.Chlorine in association with Sodium:in a situation of normal sodiemia, hyper-chloremia is a sign of metabolic alkalosis, or ofcompensatory respiratory alkalosis; hypo-chloremia, on the contrary, is a sign of metabolic acidosis,or of respiratory acidosis.Transaminase (SGOT and SGPT):they increase in the case of a hepatic pathology.Uric acid:terminal metabolite of purines, main constituent of nucleic acids.Proteolisis Inducing Factor (PIF):produced directly by the cancer cells, it is found in the circulating blood. PIF induces thedestruction of the muscular proteins so as to feed the cancer cells themselves with the essentialamino acids, vitamin B12 and folic acid. In this way the wasting syndrome is started. It is useful tomonitor it in association with Omega-3 (EPA and DHA).273

Chap. 14.2:Using phyto-medicines with anti-inflammatory activity(SEE also chapter 3)1) Aegle marmelos: it also has a sedative action; and contains linolic acid, the oil from its seeds hasan anti-bacterial effect.2) The bark of Aesculus hippocastanum: it is rich in bioflavenoids, it increases the resistance of thecapillaries, and decreases their permeability with an anti-inflammatory and anti-edemigeneeffect.3) Aloe arborescens or barbadensis (vera) mixed with good quality biologically produced honey(SEE chapter 4.b).4) The bark of Azadirachta indica (arishta, nimba, neem, the sacred tree): Nimbidina (400mg/kg)is comparable to Fenilbutazone (100mg/kg): the plant also contains Quercetine and Rutine; theessential oil is also anti-bacterial (Staph. aureus, E. coli, S. pyogenes) and also acts on intestinalworms. It is a potent natural insecticide, in India it is also used in crops to protect the nearbyplants.5) Baliospermum montanum (Danti): a promising plant, the roots are currently under study to cureadvanced hepatopathies, with ascites, jaundice etc...6) Acetonic extract of Boerhaavia diffusa (Punarnava): it inhibits the increase in activity ofaminotransferases in arthritis, in a similar way that Hydrocortisone does.7) The bark of Boswellia serrata: it blocks the 5-lypoxigenase enzyme, thus inhibiting the actionof the leucotriens; an immune-modulating action (extremely effective in rheumatoid arthritis); itis also suspected of having an anti-cancer action: induce apoptosis on melanoma andfibrosarcoma ( 1131 ). It contains boswellic acids, which are very anti-arthrotic. This plant causesan increase in the blood flow to the articular tissue, inhibits the inflammation mediators andsupports the polysaccharide mucus synthesis.8) Camellia sinensis (green tea): it contains different anti-oxidant substances; however it is theyoung leaves and the virgin buds which must be used, without fermenting the plant which leadsto a large part of the active substances being destroyed (SEE also chapters 3, 6 and 9).9) The mature fruit of Capsicum annuum or fasciculatum (chili pepper): in small doses it hasproved useful in cases of gastritis, hemorrhoids, chronic catarrh in the pharynx and the tubesand chronic middle ear infection.10) The fresh leaves of Cardiospermum halicacabum (during its flowering period): it reduceshypersensitive reactions; it is currently being evaluated for possible side effects; it would seemto be similar to Cortisone.11) The leaves and the flower tops of Cnicus benedictus : an effective febbrifuge. N.B. it is similarto Geum urbanum.12) Psidium guajava (guava): it has a certain activity against cachexia caused by cancer.13) Commiphora mukal: the steroid crystalline parts of its resin completely inhibit the appearance ofprimary lesions in arthritis, but in a less efficient way than Hydrocortisone. It does, however,reduce the severity of the secondary lesions in a more efficient way than Hydrocortisone orFenilbutazone.14) The bark of Crataeva nurvala: also useful to eliminate kidney stones.14) The essential oil of Curcuma longa: it prevents gastric ulcers from FANS; it has a hepaticprotective action against poisoning by Carbon Tetra-Chloride; its polysaccharides have animmune-stimulating action like Astragalus membranaceus.15) Cyperus rotondus: an anti-inflammatory, anti-pyretic, anti-histaminic.16) The leaves and branches of Eucalyptus globulus: no longer used (except for infections of therespiratory tracts).274

17) Foeniculum vulgare (wild fennel, sweet aniseed): it is effective against nausea caused byother medicines (even from Chemo-Therapy).18) The extract of Ginkgo biloba, since it is rich in flavonoids, flavones and leuco-anthocyans;some bisflavonoids (Ginketol, Isoginketol, Bilabetol) act on the cell membranes and stabilizethem; ginkolide blocks lipidic peroxidation and the formation of free radicals; it also inhibits thePlatelet Activation Factor (PAF), thus reducing the risk of thrombosis. N.B: it is counterindicated in patients with coagulation disorders; it is unadvisable to use it combined withplatelet anti-aggregants. It is effective on Amiotrophic Lateral Sclerosis ( 722 ).19) Hamamelis virginiana: it is especially rich in flavonoids, phenolic acid, Choline, andmineral salts: it is an excellent venous vasoconstricter; it reduces capillary permeability andincreases the resistance of the vasal walls, reabsorbing the edemas.20) Harpagophytum procumbens: only the secondary tuberised roots should be used; like Aloearborescens it has a good anti-inflammatory action without the side effects of FANS or,especially, of cortisones (these are immune-depressors), with no toxicity and a good analgesiceffect. It should always be taken on a full stomach and is unadvisable in pregnant women andchildren under the age of 12.21) Matricaria chamomilla (camomille): it reduces hypersensitivity to pain.22) Musa sapientum, acuminata, paradisiaca (banana): Sitoindoside I and II are extracted fromits fruit, in a ratio of 5:1, establishing complete protection against gastric ulcers, even thoseinduced by medicines. But Musa sapientum has, in man, high level of glicemia in bood.23) Chrysantellum americanum: it contains both flavonoids and saponines, it increases venoustone and decreases capillary permeability.24) Glycyrrhiza glabra: its roots and rhizome contain anti-inflammatory substances; if it is takenover a long period it can induce hypertension.25) Achillea millefolium: it contains an essential oil similar to that of Matricaria chamomilla,containing azulene and some types of lattones, which have an anti-inflammatory action.26) The leaves of Vaccinium myrtillus: it improves the venous cycle because it is rich invitamins.27) Okoubaka aubrevillei: it has recently been revalued.28) Spiraea ulmaria: like Salix alba and Aloe arborescens it contains salicylates, which have ananti-inflammatory action.29) The roots of Petasites officinalis30) Picea marina: substances useful against gastritis can be extracted from its resin.31) Pterocarpus santalinus: it has recently been revalued ( 621 ).32) The roots of Ruscus aculeatus: a powerful vasoconstrictor, it is anti-inflammatory and antiedemagene.33) The leaves of Ribes nigrum: a potent diuretic; it eliminates uric acid, and must be used withcare in patients with hypertension, because of its DOCA-like action. It has the same counterindicationsas cortisones. It contains more than 500 different types of bioflavonoids and tannins.It has anti-inflammatory properties and is therefore good to use together with Harpagophytumprocumbens.34) Rubia cordifolia: it has an anti-inflammatory activity; its cyclical hexapeptides have shownan anti-cancer activity in preclinical studies.35) The bark of Salix alba: it contains salicylates like Filipendula ulmaria and Aloearborescens.36) Scutellaria baicalensis or latiflora: its flavonoids have a marked non-steroid (FANS) antiinflammatoryactivity, very similar to that of Indometacine and Fenilbutazone, but without theirwell-known side effects; it also has anti-histaminic, anti-bacterial and anti-viral activities.37) Tanacetum parthenium: it contains 6 groups of compounds of phyto-pharmaceutical interest:flavonoids, sesquiterpenes (including Partenolide [apoptosis, 701 ]), monoterpines, heterospirochaetanolics,polyphenols and tannins. The most important active principles are lactone275

sesquiterpines, the biological effects are: a) a decrease in the excitability of the smooth muscularsystem (vasoconstriction) when there are inflammation mediators (e.g. the Immune Cascade); b)an inhibition in prostaglandine synthesis; c) a reduction in exocytosis (greater than FANS). Inpractice, this has the ability to prevent the release of arachidonic acid ( 583 ), and what is more itsanti-inflammatory action also works to inhibit the degranulisation of the polymorphonuclears( 584 ).38) The leaves of Vitis vinifera: they are rich in tannins and anthocyans; the latter act against theoxidant substances acting on the venous walls.39) Pygeum africanum: this plant contains sterols, triterpenes and pherulic esters which inhibitthe production of prostaglandine.40) The bark of Ulmus rubra or fulva: its mucilages have a great gastro-protective and antiinflammatoryeffect, especially if it is taken before meals.Chapter 14.3:Detoxification of the ill organismGenerally speaking a cancer patient has a temperature, pain and extensive inflammation of anumber of organs and/or systems. The temperature induced by the Immune Cascade uses up vastquantities of energy: and this can cause a reduction both in the cancerous mass (a positive effect)and in muscle mass (a negative effect). The patient’s temperature should, therefore, be kept underconstant clinical control. Similarly, very acute inflammatory processes with worsening pain cancause acute pain for the patient.In our work, where particular attention is given to immune therapy, the following must beconsidered:A patient’s temperature is an important part of their immune defense system to get lysis of thetumor mass, therefore considering temperature as a type of endogenic hyperthermia, since it isinduced by the white blood cells as an auxiliary action against the cancer mass (SEE “Hyperthermiaas cancer therapy”).A temperature, however, weakens a patient, causing a considerable loss in weight, and anappropriate diet must therefore be supplied.The anti-cancer immune response, if it is present, is characterized by the presence of intermittenttemperature peaks, of variable duration and intensity, since the temperature in general does not gohigher than 37.5 –38.5 ° C, always in the afternoon, and lasts quite long (several hours) only if thereis a considerable cancer growth present.The temperature must be differentiated from concurrent infections.Paracetamol could be used, because it does not interfere with the inflammatory processes, and itshould be used in combination with phyto-therapy (in particular Aloe arborescens) in the inductionphase of the anti-cancer Immune Cascade, and only if the patient is in pain which cannot be bornewith other phyto therapies.The clinical experience matured in these years of free professional activity at many patients’ houseshas definitely convinced the author of this work that what dr. Gerson demonstrated more than 50years ago is right. Hepatic detoxification through coffee enemas (Coffea arabica) is the key to thesolution of inflammatory and pain problems all tumour patients go through when the Immune276

Cascade reaches its maximum levels, with the ESR being far beyond its normal limits, andextremely high neoplastic markers. Very often the patient’s family panics, and the generalpractitioner is not ready to cope with the natural evolution of white blood cells’ Immune Response:they finally attack the tumour itself in depth…We would like to stress that hepatic detoxification is dangerous for patients who already underwentchemotherapy, and that what is described in this chapter must be considered a part of the therapythat was described up to now.Tumour mass is made up by necrotic material, inflamed immune cells, connective tissue, and, ofcourse, by neoplastic cells with various degrees of activity. From 3-4 PM until 3-4 AM, the ImmuneResponse (Immune Cascade) takes place: the tumour is inflamed, toxic substances are released inblood, as well as dozens of pro-inflammatory molecules and many other dangerous or harmlesssubstances coming from the tumour.From 4 AM to 11 AM the patient detoxifies from all toxic material released by the tumour duringthe inflammatory response that took place during the previous hours. The liver is the key organ for acorrect detoxification from all these substances, followed by the kidneys and the skin along with itsmucosae (tongue, gastroephageal system). The list of substances is very wide, and is not one of thesubject matters of this work.First of all, we can say that necrotic tissue can be divided into two types:1) “necrotic tissue with coagulation”: it is biochemically characterized by protein denaturationand, morphologically, by the progressive disappearance of tissue structure that will becomea white-grey mass with isolated nuclear debris.2) “necrotic tissue with colliquation”: it is produced both by autolysis and heterolysis.Two important factors limit the growth of solid tumours, not depending on the immune response:first, the tumour mass is highly and chaotically vascularized, and, as a consequence, the internalneoplastic tissues receive less nutrition by “diffusion”. The minimum distance between cancerouscell and capillaries has to be smaller than 150-200 micrometers, and the distance goes to 100micrometers if you consider the diffusion capability of oxygen, which is necessary for cellularrespiration. The internal pH of tumour mass is acid, with lack of nutrition, wide necrotized areas,and most neoplastic cells being “sleepy”. As ESR values increase, in the months following thebeginning of the Immune Cascade, we will see more and more tumour markers in circulating blood,as well as Lactate dehydrogenase, and many other substances released by the tumour or by whiteblood cells (granulocytes) penetrating the tumour’s necrotic mass.Out of these substances, many are highly toxic, and enfeeble the patient, intoxicating the liver andother organs, this way marking the failure of the therapy described in this book. Other substancesproduced directly from the tumour also deserve our attention for the dangers they bring to thepatient, as for example the Proteolisis Inducing Factor (PIF), that induces the destruction ofmuscular proteins in patients in order to nourish tumour cells themselves with essential amino acids,vitamin B12 and folic acid. PIF also induces the wasting syndrome.There are many substances released in blood by the tumour during inflammation:Intermediate filaments such as Cytokeratins,Vimentin, Desmin, CEA, alpha-feto-protein, PSA, CA15.3, CA 19.9, CA 125, other tumour markers, Bombesin, Chemochines (dangerous), somemorphine-mimetic endogenous opioid peptides (e.g., metencephaline, adrenorphine), plasminogenactivators (with the function of proteolysis for self-maintenance and expansion processes in thetumour itself), paraneoplastic prothrombins (without end debris of gamma-carboxyglutamic acid),Transforming Growth Factor (TGF), Tumor-Derived-Growth Factor (TDGF), Tumor-Derived-Angiogenic-Factors (TAF), Insulin Like Growth Factor –I (IGF-I), Fibroblast Growth Factor(FGF).277

Neoplastic cells produce these substances for different reasons; the simplest one is that theycompete with their host. The tumour tries to grow autocrinally: it produces specific growth factors,and malignant cells will then proliferate. Thus, oncogenes are allegedly responsible for the cellscapability of growing independently through three effects:1) coding the factor that self-stimulates growth,2) coding its receptor,3) amplifying phytogenous signals coming from the growth factor linked to the receptor itself.The liver has the fundamental role of deactivating all substances produced by the tumour. However,to do so it needs vitaminic hepato-protective substances, such as those contained in phytotherapicproducts that classic Western medicine has knows for thousands of years: Silybum marianum,Taraxacum officinale, Smilax aspera, Cynara scolymus, Salvia officinalis, Agropyrum repens,Hyssopus officinalis, Matricaria camomilla, Aloe species, etc… They are extremely effective onmany degenerative or toxic processes for the liver.Proinflammatory mediators coming from the Immune Cascade are also dangerous for the patientsthemselves, if the immune response, given by the ESR, cannot be controlled by the generalpractitioner, risking to provoke very dangerous immune responses (indicated by ESR, tumourmarkers and very high Lactate dehydrogenase). Inflammation mediators can especially give longlastingand severe pain on the nerves close to the area where the immune response takes place.As the Immune Cascade is a defence of the organism, especially at night, according to Gerson thedoctor should suggest coffee enemas, at 35-36 Celsius degrees, to be done during the afternoon,before night. One hour before this, the patient should be given at least one spoon of castor oil (thelatter is however forbidden in patients who already underwent chemotherapy).Coffee (Coffea arabica) opens the bile ducts in the liver. These are full of tumour toxinsaccumulated in the previous days, which are in this way discharged in the intestine. The liver is nowready to absorb new tumour toxins: they are produced by another granulocyte attack, and they willbe discharged in blood. This will cause another inflammation process at night, a part of the immuneresponse that is recognizable already in the afternoon, when the patient gets a temperature.The second or third coffee enema is advisable during the same night, before 4AM (when theImmune Cascade ends), ideally around 8-9 PM, and again shortly before midnight, when thequantity of toxins and pro-inflammatory substances in blood is very high.If the patient suffers from insomnia because of the enemas administered at night, the enemas willhave to be performed in the morning and in the afternoon, one every 4-5 hours.As Gerson said ( 749 ), the gut walls and hemorrhoidal veins absorb most of the caffeine in coffee.From the hemorrhoidal veins caffeine is discharged in the portal vein and then into the liver, whereit opens bile ducts, thus allowing rapid elimination of tumour toxic substances accumulated in theprevious hours.When the enema liquid enters the colon, it should be kept inside for no more than 15 minutes, sothat it is not absorbed systemically. Ideally, the liquid should be kept inside exactly for 12 minutes,according to Gerson’s method ( 749 ), as we can read in this important medicine book:“…While the coffee enema is being retained in the gut (for an optimum period ranging from twelve to fifteen minutes),all of the body’s blood passes through the liver every three minutes. The hemorrhoidal blood vessels dilate fromexposure to the caffeine; in turn, the liver’s portal veins dilate too. Simultaneously, the bile ducts expand with blood, the278

ile flow increases, and the smooth muscles of these internal organs relax. The blood serum and its many componentsare detoxified as this vital fluid passes through the individual’s caffeinated liver.The quart of water being retained in the bowel stimulates the visceral nervous system, promoting peristalsis. The waterdelivered through the bowel dilutes the bile and causes an even greater increase in bile flow. There is a flushing of toxicbile which is further affected by the body’s enzymatic catalyst known to physiologists as glutathione S-transferase(GST).The GST is increased in quantity in the small bowel by 700 percent, which is an excellent physiological effect, becausethis enzyme quenches free radicals. These quenched radicals leave the liver and gallbladder as bile salts flowingthrough the duodenum. The bile salts are carried away by peristalsis in the gut, travelling from the small intestine,through the colon, and out the rectum.In 1990, the Austrian surgeon Peter Lechner, M.D., and his colleagues, who had been investigating Dr. Gerson’s cancertreatment, discussed the benefits of increasing quantities of GST in the gut. It was then that Dr. Lechner reported:GST binds bilirubin and its glucuronides so that they can be eliminated from the hepatocytes (liver cells)GST blocks and detoxifies carcinogens, which require oxidation or reduction to be activated. Its catalytic functionproduces a protective effect against many chemical carcinogens.GST forms a covalent bond with nearly all highly electrophilic (free radical) substances, which is the precondition oftheir elimination from the body. The intermediate products of potential liver poisons (hepatotoxic cytostatics) alsobelong in this category of forming free radical pathology.Before the above published finding, Dr. Lechner had decided in 1984 that the coffee enema had a very specific purpose:lowering serum toxins. His medical report states, “Coffee enemas have a definite effect on the colon which can beobserved with an endoscope. Wattenberg and coworkers were able to prove in 1981 that the palmitic acid found incoffee promotes the activity of glutathione S-transferase and other ligand by manifold times above the normal. It is thisenzyme group which is responsible primarily for the conjugation of free electrophile radicals which the gall bladder willthen release”.Starting in the late 1970s, the laboratory owned and supervised by biochemist Lee W. Wattenberg, Ph.D., identified twosalts of palmitic acid, cafestol palmitate and kahweol palmitate (both present in coffee), as the potent intensifiers ofglutathione S-transferase. Such enhancement turns this enzyme into a major detoxification system that catalyzes thebinding of a vast variety of electron acceptors (the electrophiles) from the blood-stream to the sulfhydryl group ofglutathione. Because the reactive ultimate carcinogenic forms of chemicals are electrophiles, the glutathione S-transferase system becomes an important mechanism for cleaning away any existing cancer cells (carcinogenicdetoxification).This detoxifying of cancer cells has been demonstrated innumerable times by experiments on laboratory mice whwreindetoxification of the liver increases by 600 percent and the small bowel detoxifies by 700 percent when coffee beans areadded to the animals’ diet. Analogous results take place within humans who are giving themselves coffee enemas.We can state that coffee enemas stimulate bile duct dilation, thus helping in the elimination oftumour toxins through the liver and the dialysis of blood toxic debris through the colon walls.The coffee enema is in a class by itself as a therapeutic agent. In no way does the oraladministration of beverage coffee have the same effect as its rectal administration. On the contrary,drinking coffee virtually ensures reabsorption of toxic bile, While other agents classed asstimulators of bile flow (choleretics) do increase bile production from the liver, they hardly enhanceany detoxifying by that organ’s enzyme systems. Choleretics do nothing to ensure the passage ofbile from the intestines out the rectum. It’s a physiological fact that bile is normally reabsorbed upto ten times by the body before working its way out of the intestines in feces. The enzyme –intensifying ability of the coffee enema is unique among choleretics. Because it does not allowreabsorption of toxic bile by the liver across the gut wall, it is an entirely effective means ofdetoxifying the bloodstream through existing enzyme systems in both the liver and the smallintestine. Inasmuch as clinical practice has taught clinicians utilizing the Gerson Therapy that coffeeenemas are well tolerated by patients when used as frequently as every four hours in a twenty-fourhourperiod, the coffee enema should be categorized in the medical literature as the onlynonreabsorbed, effective, repeatable choleretic agent.279

Such a classification could go far to bring about the healing of pathologies that require quickabsorption and no reuse of bile.Dr. Gerson hypothesized on the physiological actions and effects of coffee enemas and observedtheir clinical benefits.Introducing a quart of boiled coffee solution into the colon will accomplish the followingphysiological benefits:It dilutes portal blood and , subsequently, the bile.Theophylline and theobromine, major nutraceutical constituents of coffee, dilate blood vessels andcounter inflammation of the gut .The palmitates of coffee enhance glutathione-S-transferase, which is responsible for the removal ofmany toxic radicals from blood serum.The fluid of the enema itself stimulates the visceral nervous system, promoting peristalsis and thetransit of diluted toxic bile from the duodenum out the rectum.Because the stimulating enema is retained for up to fifteen minutes, and because all the blood in thebody passes through the liver nearly every three minutes, coffee enemas represent a form of dialysisof blood across the gut wall.Chap. 14.3.a:The usefulness of Potassium for human metabolism(From : “Charlotte Gerson : The Gerson Therapy)Potassium (chemical symbol K) is a mineral element needed by all plants and animals to live andthrive: It is the essential mineral required within all tissues and cells in the body for normal smoothfunction and for all their activities. Since it is required in the cells, not in the fluids, it is referred toas the “intercellular” mineral. Potassium is contained in all foods, particulary in fruits, vegetables,and whole grains. Animal sources, such as fish and meat, also contain potassium, but the plantbasedmaterial is easier to absorb.Potassium is absorbed from foods through the intestinal tract; any excess is released in the urine.The kidneys play an important role in determining how much potassium is released or absorbed intothe system. If the kidneys are irritated by chemicals, drugs or other problem, they may release toomuch potassium, contributing to a deficiency Potassium can also be lost through vomiting, diarrheaand surgical drainage, as well as laxatives and diuretics (agents that increase the flow of urine).Loss through the skin is rare but it can result from sweating during too much exercise or whenoverheated ( 1417 )Part of the Gerson Therapy involves consuming a diet not only loaded with high-potassium foodsbut also supplemented with elevated doses of the mineral itself. In fact, Dr. Shoham wrote: “Potassium obviously is a central pillar in the whole structure of Dr. Gerson’s therapy. We aredealing here with enormous amounts of K - about 20 grams in the supplemental potassium solutionduring the first four weeks, reduced to half thereafter, about nine to ten grams in the juices, andprobably two to three grams in the food, all together about thirty grams per day during the firstweeks and then twenty grams per day subsequently”.280

Dr. Jacob Shoham was concerned about the possibility of hyperkalemia, an overabundance ofpotassium in a person’s metabolism, which could possibly occur from a patient’s conforming to theGerson Therapy recommendation of K supplemention. Yet adverse signs or symptoms ofhyperkalemia are not an effect from the high dose of potassium supplementation. Several GersonTherapy patients have accidentally, through misinterpretation of labelling, self-medicated withpotassium at levels approximately thirty-two times the recommended dosage of K for periods of upto three weeks. They did this without undergoing any significant adverse effects. Over time, fromexperience of users, elevating K intake to neutralize too much sodium (Na) in the tissues appears tobe safe and effective. Excess K is easily excreted by normal kidneys.Also, more than forty years ago, Dr. Gerson answered the hyperkaliemia question in his celebratedbook. He declares: “The content of potassium in the serum is, in many cases, misleading. “Then gegoes on to say, “It [potassium in serum] does not give any definite indication of an increasing ordecreasing amount of K present in the tissues of essential organs…More coincident examinations of K made at the same time in serum and tissues and in differentstages of the [cancerous] disease, are necessary for such decisions“.Dr. Gerson advises that hyperkaliemia occurs from seven specific sources:1) “loss of fluids – blood, in majority of cases dehydration”;2) “Epilepsy –most cases”;3) “Cancer patients more often in the period before they go over to the terminal stage (on theway to elimination)”;4) “Never in cancer patients during restoration time”;5) “Addison’s disease”;6) “Anuria – uremia (inability of liver and kidneys to excrete excess potassium in solution –lostfrom essential organs)”;7) “Acute and chronic asthma, and other degenerative allergies”.Potassium belongs to a chemical group that is associated with both phosphoric acids andcarbohydrates, and the three substances readily combine with colloids; therefore, Dr. Gersonsuggests that we may speak of these four grouped ingredients of the metabolism as the potassiumgroup. Na is part of its own chemical group, the sodium group.We take in an enormous amount of sodium, not necessarily with the foods we prepare ourselves butwith those we purchase already packaged, especially those mixed ingredients that people eat inrestaurants. Dining outside the home is an unhealthy way to eat and live. It’s an underlying sourceof degenerating illnesses such as high blood pressure, stroke, and cancer. In his monthly newsletterHEALTH AND HEALING, Julian Whitaker, M.D., writes “The way to bring your sodiumpotassiumratio back into balance is to eat lots of vegetables, legumes, whole grains, and fruit.These whole-some foods naturally have an excellent sodium-to-potassium ratio of at least 1: 50….“ ( 1418 ).Dr. Whitaker adds that some fruits, such as oranges, offer a good mineral proportion of 1 partsodium to 260 parts potassium.281

Chap. 14.3.b:Potassium supplementation on the Gerson Therapy(From : “Charlotte Gerson : The Gerson Therapy )At the Gerson Therapy hospitals, when patients are beginning their therapeutic programs, bloodtests and urinalyses are performed once a week. This would be the case when someone is under thecare of a Gerson certified practitioner as well. Monitoring of blood and urine values of patients on acontinuous basis is of great importance.Monitoring laboratory tests should be repeated about every six week, depending upon the severityof an individual’s disease process. In the early stages with the debilitated patient, every four weekswould be recommended. These laboratory studies must accompany numerous clinical examinations.One of the most important laboratory tests involves the determination of the blood serum’spotassium levels. K levels for sick Gerson patients will often fall between 5,9 and 6 milliequivalentsper liter (mEq/L). Normal ranges for non-Gerson patients generally record at 3,4 to 5,1 mEq/L.(The Gerson Institute. Gerson Therapy Practitioner’s Training Seminar Workbook. Bonita,California : The Gerson Institute, 1996, pp. 31)Particularly in the initial stages of treatment, Gerson patients ingest significant potassiumsupplementation of up to 150 mEq/day. Even in the presence of elevated potassium serum levels,it’s necessary to continue K supplementation. Dr. Gerson tells us that K ions are indispensable incertain enzymatic reactions and K plays a role in tissue protein synthesis. Normally, muscles, brainand liver possess much higher K content than Na content. As long as K remains normal, Na isdiminished, and that’s maintaining a healthy state.At the Gerson Therapy hospitals, after blood testing upon the patient’s hospital admission, 10percent potassium solution is administered immediately. The K administration takes the form of 4teaspoonfuls ten times daily added to all juices, and this dose usually continues for three to fourweeks.Then the amount of K is reduced to half. Presenting a warning, Dr. Gerson says : “The combinationof the blood level with the clinical observations teaches us that the restoration of the potassiumcontent in the organs is a difficult and long-drawn-out process”.A compound solution of potassium salts is made from 33 grams (g) each of potassium acetate,monophosphate, and gluconate, diluted in 32 ounces of distilled water. As stated, dosages vary from1 to 4 teaspoonfuls (tsp), representing from 3,5 to 14 grams of K per day. This medication is addedin equal amounts to each of the carrot/apple, greens, and orange jouces (but not to the pure carrotjuices) daily, about 1 to 4 tsp per jouce drink.We place emphasis on medicating with potassium because it forms a keystone for achieving healingbenefits from use of the Gerson Therapy. This K medication is primary to the treatment of tissuedamage syndrome (the penetration of Na into tissues), found in all cancers and in most otherdegenerative diseases. It combines with the other medications and dietary regimen to increasecellular K levels, reduce intercellular edema, and restore normal cell function.As we alluded before, patients have experienced some misunderstandings using this high-dose Kmedication, even though instructions are provided on the container. You must dilute the contents ofthe container holding the concentrated K powder into 32 ounces of water. Spoon the diluted liquidyou have created into the juices. Do not spoon the powder itself into the juices or you will bemixing in an overabundant dose. No adverse side effects occur at this usual dosage, except perhaps282

for an irritation in the throat due to the strong potassium salts. Eating oatmeal gruel heals thepotential throat irritation.Store the potassium solution in a glass container rather than in plastic or metal. It needs norefrigeration but should be held in a dark closet (pantry) or stored in a brown-or amber-coloredbottle or jar. One quart of potassium solution will last from one to three weeks, depending on theprescribed dosage. Discard any of the remaining potassium solution and replace it if, after sometime has elapsed, it becomes cloudy.Chap. 14.3.c.:Potassium compound for one’s enema solutionFrom : “Charlotte Gerson : The Gerson TherapyThe same potassium solution that is added to juices for drinking may be applied directly to enemasfor the relief of abdominal spasms that occur from colon contractions. The dosage of this potassiumcompound consists of 2 to 3 tsp of K solution placed into each enema. At times, lesser amounts ofwater combined with the potassium compound for enemas may be required simply because theabdominal spasms may be too great to accept any increased liquid pressure into one’s colon.Discontinue adding potassium compound to the coffee enema after six to eight days or it will causeirritation of the colon.Tissue damage syndrome from cellular poisoningAccording to a 1977 published report by Freeman Cope, M.D., a pioneering physician and researchphysicist, medical science has learned that cellular structures become poisoned by exposure tocarcinogens, atherogens, antigens, allergens, and other offending pollutants in our surrounding. Thecellular pollutants may cause oxygen starvation, trauma, generalized insult, or other tissue damageof the cells that takes the form of a syndrome, a series of symptoms and signs that manifestthemselves in a repeated pattern. Any part of the body can undergo tissue damage syndrome, acycle of cellular destruction, which Dr. Cope defines as “the damaged configurational state inwhich the cell proteins lose their preference for association with K+ rather than Na+ , and thewater content of the cell increases (the cell swells)”As described by Dr. Cope, the tissue damage syndrome presents an ill patient’s dysfunctional cellswith this series of pathological symptoms:1) The damaged cells lose potassium2) The involved cells readily accept sodium3) The cells swell with too much waterThe symptom that may be recognized most readily by the attending health professional is thenlabelled cellular edema.Cellular edema does not allow for the manufacture of energy in the form of adenosine triphosphate(ATP). ATP is the energy storage compound of the body; it’s the energy currency that results fromburning sugar through oxidation. ATP gets manufactured, then it’s used up, is manufactured again,and becomes used once more on a continuous basis. During the course of this metabolic process,ATP liberates bursts of energy for cellular use. ATP is an adenosine molecule possessing threestrong phosphate bonds that contain the required energy. The cell must have ATP or it dies. If283

enough cells die, tissue dies. If too many tissues die, an organ or body part dies. If too many organsdie, the person dies.When an excessive amount of water is present in the cell, the production of ATP is inhibited orstops altogether. At the same time, protein synthesis and lipid (fat) metabolism stops. On theGerson Therapy, the damaged cell is confronted with less sodium, is allowed to bind withpotassium, is delivered of its excess water content, and is improved in its mitochondrial function.Certain organelles, those tiny chemical factories inside of each cell called “mitochondria”, performthe energy functions of burning sugar with oxygen, synthesizing protein, and metabolizing fats.To eliminate the excess cellular water which shows up as edema, before Dr. Freeman Copedescribed and named tissue damage syndrome, Max Gerson was treating the condition as far backas the 1920s. Dr. Max Gerson eliminated sodium from the diet, fashioned an eating program thatwas high in potassium, supplemented the diet with additional potassium, and developed the meansto remove from the bloodstream toxins that inhibit normal cellular enzyme functions, metabolism,and respiration.To paint a defining picture of just what tissue damage syndrome is, think of Dr. Cope’s discovery inthis way. See the cell as an industrialized nation with its mitochondria as the nation’s industrialcities. They are the cities of industry. When a cell (as the nation) has lost potassium, gained sodium,and swollen with water, it’s equivalent to all of its cities’ sewers backing up. Then the industrialcities are shut down in their function. Energy cannot be made by the cities of industry to clean outthe sewers. The entire industrialized nation (that damaged cell) becomes over-polluted, becomesseverely dysfunctional in every facet of its existence, and dies. Tissue damage syndrome has beenthe responsible agent for cellular death.By eating the saltless diet and supplementing with elevated doses of potassium, clinicallyundiscernible but laboratory-measurable tissue damage syndrome can be avoided. During the timethat Dr. Max Gerson was writing his life-saving book “A Cancer Therapy Results of Fifty Casesand The Cure of Advanced Cancer by Diet Therapy: A summary of 30 Years of ClinicalExperimentation“ this information was published in the American Cancer Society’s healthprofessionals’ journal Cancer ( 1416 ). There is no better means of removing the puffy malfunctioningsphere of partial metabolites and cellular edema from diseased tissue materials than application ofthe Gerson Therapy’s saltless and high-potassium diet.Note 1: it is very important to use great quantities of fresh fruit shakes and organic fresh vegetables,as great quantities of potassium and magnesium are lost by the body through diarrhea caused byenemas. Thus, it is also necessary to do regular blood tests, especially for potassium.Note 2: in other therapies described by other authors, Aloe vera enemas were performed, withprocedures very similar to Gerson’s method. Using Aloe vera for enemas could be as effective asusing coffee, or even better, as this plant has choleretic effects for the liver (that is, it detoxifies bileducts) and laxative effects for the guts. In this way toxic substances are not reabsorbed by the gutwalls.Personally speaking, the author does not consider the use of opioids opportune under anycircumstances, unless it is absolutely necessary because the cancer patient is in a painful anddisabling condition which other medicines or phyto medicines cannot remedy: this is to preventlosing the active collaboration of the patient in the multifactorial therapy set forth in this work,where apparently marginal factors like diet on the contrary have a primary importance if a suitabletherapy is to be correctly followed.284

Chap. 15: Phytotherapics with antiangiogenesis actionThe term angiogenesis refers to the process of ramification and growth of pre-existent bloodvessels, whose walls are made up by only one layer of endothelial cells. During the regular growthprocess, angiogenesis helps the body to repair damaged tissues. Growth of blood vessels isregulated by proangiogenic and antiangiogenic factors produced by the body. This mechanism isactivated by substances such as the Vascular Endothelial Growth Factor (VEGF), and isdeactivated by growth inhibitors such as Thrombospondin.When the mechanism that controls this equilibrium is altered, such as in tumours, an anarcoid net ofblood vessels is created. Angiogenesis is thus the growth of small blood vessels that, in oncology,are particularly important: it is possible to use substances capable of inhibiting tumour growththrough blocking the growth of its vessels in a rather selective way. This has a special importance,given the high interstitial fluid pressure (H-IFP, see: Jain R.K.: Barrier to Drug Delivery in Solid Tumors,Scientific American, Science, July, 1994) that in tumour masses hinders penetration of antineoplasticdrugs, of Natural Killer lymphocytes, Killer lymphocytes, macrophages and cytotoxic T cells ( 391 ).The first proangiogenesis molecule was discovered in the 70s and was called VEGF (VascularEndothelial Growth Factor), but it was considered to be a simple vascular permeability factor.In fact, it is the most important proangiogenic factor in tumours.Isolated in 1989, it can be deactivated in different ways:1) Specific Monoclonal Antibodies that deactivate the molecule.2) Soluble forms of VEGF cell receptors, that are able to catch the growth factor before it linksto the cells.3) Small molecules that can enter the cells and block growth messages that VEGF sends toendothelial cells after linking to receptors on the outer surface.4) Use of Alfa-Interferon.5) Metal proteinase inhibitors: these molecules block the release of VEGF from where it isaccumulated inside the extracellular matrix.In any case, even small residual quantities would be enough to sustain the proliferative action of thetumour, as the action of VEFG is effective also in very low concentrations. Furthermore, the tumourcan still use other substances, such as the fibroblast growth factor and Interleukin 8. Since the 60sresearchers noticed that when the primary tumour mass is removed, the small metastases startgrowing very quickly, as if the production of tumour inhibiting substances stopped when removingthe tumour. These inhibiting substances were later identified by Folkman in 1994 (Angiostatin) andin 1997 (Endostatin); ( 113 ).About twenty more substances with antiangiogenesis action are now being studied ( 55, 115, 384,518 ),many of them are natural.For example, Camellia sinensis (green tea) should have some inhibitors of Gelatinases; in ReneCaisse ( 517, 520 ) tea there could be an angiogenesis inhibition factor, Genistein, contained in theflowers of Trifolium rubeus; shark cartilage was considered in the past ( 518 ), and so it was sold inproducts that were suitable for administration in patients unless they had had surgery in recenttimes, and in any case in absence of clinical records of Angina pectoris, heart attacks, TIA(Transient Ischemic Attack), RIND (Reversible Ischemic Neurological Deficit), Ictus and othersevere vascular conditions.For lung tumour (not with small cells), the natural inhibitor Neovastat AE-941 was discovered, andBMS275291 was synthesized; for breast and prostate cancer, Marimastat® was synthesized, forkidney tumour and multiple mieloma Talidomide® was suggested.But most of all, it was discovered that Alfa-Interferon would inhibit the release of growth factorssuch as VEGF. Therefore, as Alfa-Interferon is a part of the Immune Cascade produced by the body285

itself against the tumour (see chapter 4), according to the author of this work all this should beconsidered as one more reason not to perform chemotherapy under any circumstances.Resveratrol is contained in Vitis vinifera, in Poligonum cuspidatum and in Yucca schidigea ( 1118 ),and it has shown to be effective.Morinda citrifolia can also inhibit angiogenesis ( 1172 ).http://www.erbeofficinali.org/dati/nacci/studi/articolo%20sul%20NONU%20(morinda%20citrifolia)%20attiva%20contro%20tumore%20al%20cervello_1.pdfOther plantsCombretum coffrum is a characteristic tree in South Africa, and its roots contain Combrestatin. Thissubstance acts on blood vessels, diminishing their flux, with a different mechanism fromangiogenesis inhibitors. Combrestatin A4 interacts with microtubules forming the cytoskeleton ofendothelial cells. The latter change their shape, they become round and interrupt blood flow insmall blood vessels. The quantity of nutrition that arrives to cancerous cells is then reduced, andcancerous cells die.It is accepted that aberrant angiogenesis essential for the progression of solid tumours andhaematological malignancies, thus, antiangiogenic therapy, is one of the most promising approachesto control cancer.Perillyl alcohol (POH) which is the hydroxylated analogue of Limonene, has the ability to interferewith angiogenesis ( 1604 ) Lautrari H.: Perillyl alcohol is an angiogenesis inhibitor, J. Pharmacol.Exp. Ther. 311, pp.: 568-575, 2004.http://www.erbeofficinali.org/dati/nacci/studi/Perilly%20alcohol%20inhibitor%20of%20ANGIOGENESIS.pdfLimonene showed antiangiogenic and proapoptotic effects on human gastric cancer implanted innude mice, thus inhibiting tumour growth and metastasis (Guang : Inhibition of growth andmetastasis of human gastric cancer implanted in nude mice by d-limonene World J. Gastroenterol.10, 2140-2144, 2004).Note: against tumour biopsyThe author of this work is absolutely against any type of biopsy on malignant tumours or suspect malignant tumours.Clinical experience in the past few years has almost always shown the metastatizing explosion of malignant tumours ifpartially removed.This metastatizing explosion must be probably traced back to the proangiogenic effect of inflammation, that is the resultof the inappropriate biopsy.286

Chapter 16: Based-Protocol of Dr Giuseppe Nacci (M.D.),for Cancer TherapyNote 1: This diet-therapy is here outlined but it is important toremember that only a medical doctor can prescribe it and that doctorNacci waives all responsibility in case of people who want to undergoit without consulting a medical doctor.Note 2: This diet-therapy is USELESS in patients under CHEMO-Therapy and/or after CHEMO-Therapy.Patient that have received Chemo-Therapy can have well over a lethal amount of Chemo-Therapylodged within their body. When this therapy begins to work, it can very quickly dislodge toxins,including Chemo-Therapy residue from cells, into the bloodstream. Patients with these largeamounts of toxins being released into their bloodstream often cannot detoxify their body fastenough if they are using this standard intensive therapy and patients may be prone to liver failure.The diet should be very poor in Sodium Chloride (NaCl), Glucose, Yeasts,Proteins (is “protein” if has ALL 9 ESSENTIAL AMINO-ACIDS) Folic acid,vitamin B12.Therefore the following foods should be excluded: Meat, Eggs, Milk (it’s liquid Meat), milk byproducts(Cheese, Cream, Ice-cream, Yogurt, Butter…), Yeast and/or Mushrooms, Algae, plantSprouts, and other (SEE below).1) NOT Milk (it’s liquid Meat), and milk by-products (Cheese, Cream, Ice-cream, Yogurt,Butter…) ; they contain Growth factors, CASEIN, ALL 9 ESSENTIAL AMINO-ACIDS,Folic acid, and vitamin B12; note: Sodium Chloride in Cheese2) NOT Meat, Ham, SALUMI, Liver, Lard…: they contain ALL 9 ESSENTIAL AMINO-ACIDS, Folic acid, and vitamin B12; note: Sodium Chloride in the Ham and Salumi sausage(salted pork meats).3) NOT Eggs : they contain ALL 9 ESSENTIAL AMINO-ACIDS, Folic acid, and vitaminB12;4) NOT plant Sprouts : they contain ALL 9 ESSENTIAL AMINO-ACIDS, Folic acid, andvitamin B12;5) NOT brewers’ Yeast and/or Mushrooms (NOT Bread and/or Pizza): they contain ALL9 ESSENTIAL AMINO-ACIDS, Folic acid, and vitamin B12;287

6) NOT Algae: they contain ALL 9 ESSENTIAL AMINO-ACIDS, Folic acid, and vitaminB12;7) NOT Sugars (high glicemic curve) : NOT sugar Beets, Chips, Cornflakes, Crisps, Jam,Molasses, Muesli, Popcorn, Raisins.8) NOT Aspartame (E951) it induces cancer http://www.ehponline.org/docs/2007/10271/abstract.html9) NOT Pickles10) NOT American Pasta (it has Folic acid for FDA-Law (In 1998, food fortification with folic acidbecame required by the FDA for a variety of grains, flour, and baked goods.)11) NOT Margarine, hydrogenated vegetable Fats, Coconut, palm Oil : saturated fats andthey damage cell walls and hinder the action of vitamin F12) NOT Saccharine (E954)13) NOT vitamin integrators (both synthetic and natural), if containing PABA, Folic acid,vitamin B12, SAM (S-adenosil-methionine), Carnitin (2 essential amionoacids: Lysin andMethionin)14) NOT dried Fruit (it contains a lot of ESSENTIAL AMINOACIDS) : Corylus avellana(hazelnuts), Olea europaea (olives), Pinus pinea (pine nuts), Castanea sativa (sweetchestnuts),Juglans regia (walnuts), Arachis hypogaea (peanuts), Pistacia vera (pistachios),Prunus amygdalus (almonds);Note: be careful with seeds of bitter almonds (Prunus amygdalus), because they contain a lot ofvitamin B17. This makes 2-3 bitter seeds lethal for a child, and 12-15 lethal for an adult weighing70 kg. On the other side, they are extremely effective on cancer (SEE chapter 7).Blood values to check every month:Total proteins: these are very important, patients must follow a hypoprotein diet, withlimit values ranging from 6.0 to 6.2 g per 100 ml blood.Lower values are dangerous (denutrition).The author of this work usually improves lower protein values by prescribing cerealsassociated to legumes or bluefish.The use of fruit or vegetable seeds, which are rich in vitamin B17 and unfortunatelyalso in essential amino acids, is therefore very DELICATE, as there is theparadoxical risk of giving protein substances to tumour.288

THERAPYAccording to the author, the diet should be based on :* 9-15 daily portions of fresh vegetables, fresh fruit, apple vinegar, ….SEE chap. 1, 2 and 3* Flax oil (vitamin F)* 9-15 tablespoons of Aloe arborescens (1-2 tablespoons every 2-3 hours), and/or ESSIAC formule(only 4 plants, without Trifolium pratense).* 9-15 grams/day of natural vitamin C (Rosa canina, Echinacea species, Emblica officinalis,* Magnesium* Ananas sativus stalk and /or Papaia (NOT GMO)* Vitamin B17 and/or Laetrile (Note: it’s dangerous : SEE medical doctors)* Allium sativum and Allium cepa (organic Germanium and other vitamins, as Allicin, B13…)The following are useful spices (some of them carry out a specific anti-neoplastic function on animmuno-stimulating and/or apoptotic basis):Anethum graveolens or Peucedanum graveolens (dill), Hibiscus abelmoschus or Abelmoscythusmoschatus (rosemallow), Angelica archangelica, Pimenta racemosa (Pimenta), Stirax officinalis(benzoin), Dryobalanops aromatica (borneole), Aniba roseadora (Bois de Rose), Melaleucaalternifolia (Tea tree) Melaleuca leucodendron or minor (Cajeput), Melaleuca quinquenervia orviridiflora (Niaouli), Cymbopogon nardus or citratus (cymbopogon), Foeniculum vulgare orsativum (fennel), Lavandula officinalis or angustifolia (lavender), Lavandula stoechas (Frenchlavender), Myrtus communis (myrtle), Pinus mugo (mugo pine), Pinus sylvestris (scots pine), Salviasclarea, Santalum album (sandal wood), Satureja montana or hortensis (savory), Lippia citriodora(verbena), Cananga odorata (Ylang-Ylang), Viola odorata (sweet violet), Pimpinella anisum(anise), Ocimum sanctum or tenuiflorum (basil), Cinnamomum zeylanicum (cinnamon), Elettariacardamomum (cardamom), Eugenia caryophyllata or Caryophyllus aromaticus (cloves),Coriandrum sativum (coriander), Carum carvi (cumin), Carum nigrum or Nigella sativa (blackcumin), Curcuma longa (curcuma), Artemisia dracunculus (tarragon), Melissa officinalis (lemonbalm), Mentha species (mint), Origanum vulgare (oregano), Majorana hortensis (marjoram),Capsicum frutescens, fasciculatum or annum (cayenne pepper, paprika), Cochlearia armoracia(radish), Rosmarinus officinalis (rosemary), Salvia officinalis (sage), Schinus molle (Brazilianpeppertree), Sinapsis arvensis or alba (mustard), Thymus vulgaris (thyme), Crocus sativus(saffron), Piper nigrum (black pepper), Zingiber officinalis (ginger).• OTHER PLANTS: 20-30 medical plants which have apoptotic activity for the particulartype of neoplasia which is occurring (SEE chapter 6) and immunotherapy activity (SEEchap. 9) :• Ochrosia elliptica for breast cancer, Pereskia bleo, Urtica diotica and Lamium album fortumors of the stomach, tumors in female genitalia, lymphomas and leukaemia; Acalyphaindica for lung tumors; Malva sivestris or vulgaris for tumors of the larynx; Cetrariaislandica for melanoma, bone sarcoma and different types of carcinoma; Resveratrol formelanoma, Epilobium parviflorum and Copaifera officinalis for tumors of the prostate and289

the bladder; Epilobium angustifolium or Solanum paniculatum for tumors of the uterus; thebark of Betula alba (birch) for melanoma (betulinic acid); Salvia officinalis for lymphomas,leukaemia, epatocarcinoma, and carcinomas of the pancreas, (it is, however, counterindicated for breast tumors); Mimosa species, Gardenia jasminoides, Quercus robur, Betulaalba, Morinda citrifolia, Lepidozamia peroffskyana, Melissa monarda and Melissaofficinalis for glioma; Asparagus racemosus for human skin carcinoma and carcinoma of thenasopharynx; Sticta pulmonaria or Lobaria pulmonaria, Glechoma hederaceum formelanoma, bone sarcoma and different types of carcinoma; Euspongia officinalis forlymphomas; Acorus calamus for gastro-intestinal carcinoma; Rumex acetosa for gastriccarcinoma; Equisetum arvense for lymphoma, leukaemia and pancreatic carcinoma; fortumors of the lungs, kidney and bladder; Chimaphila umbellata for tumors in both the maleand female genital areas; Galium aparine for carcinoma of the tongue; Lysimachianummularia, Artemisia absinthium for gastro-intestinal carcinoma; Phyllantus niruri orArtemisia abrotanum for peritoneal carcinosis from gastro-intestinal tumors; Marrubiumvulgare for breast tumors, Plantago major for melanoma, bone sarcoma and different typesof carcinoma; Alchimilla alpina and vulgaris for carcinoma of the female genital area;Meum mutellina for melanoma, bone sarcoma and different types of carcinomas; Bacopamonnieri for sarcomas; Cerastium alpinum for carcinoma of the breast and lungs; Primulaveris or officinalis for lung tumors; Scutellaria baicalensis o latiflora for lung tumors,Gentiana germanica for breast carcinoma; Ailanthus glandulosa for tumors of the head andneck; Nelumbo nucifera for carcinoma of the stomach, Cissampelos pareira per carcinomaand leukaemia, Pimpinella major and saxifraga for carcinomas of the oral cavity, the neckand the larynx; Mormordica charantia against leukaemia, Antennaria dioica for lungcarcinoma; Gnafalium supinum or Erythrina mulungu for carcinoma of the stomach,Asparagus cochinensis for tumors of the breast and of the lungs, Verbascum thapsus ordensiflorum for melanoma, bone sarcoma and different types of carcinoma; Lapsanacommunis for tumors of the breast (hypothesized); Erythroxylum catuaba for melanoma; theflowers of Trigonella foenum graecum (only in an infusion) for lymphoma, leukaemia andpancreatic carcinoma; Maytenus illicifolia for cancer and leukaemia, Antyllis alpestris forlung carcinoma, Cerastium alpinum for carcinoma of the stomach; Sida cordifolia forleukaemia, sarcoma and carcinoma of the nasopharynx; Erithrea antaurium or Boerhaaviadiffusa for gastro-intestinal carcinoma; Houttuynia cordata for lung carcinoma, Inesinaecalea for carcinoma and leukaemia; Maytenus krukovit for melanoma; Physalis angulata autMuehenbeckia volcanica for leukaemia and testicules tumors, Sempervivum montanum forleukaemia and lymphomas; Cayaponia tayuya for sarcomas, Pfaffia paniculata per cancerand leukaemia, Serenoa repens for carcinoma of the prostate; Uncaria tomentosa for sometypes of leukaemia; Pedicularis rostrato-capitata for carcinoma of the breast; Marasdeniacundurango for gastric carcinoma; Primula hirsuta for carcinoma of the breast; Saxifragaoppositifolia for carcinoma of the breast, the uterus and for leukaemia, Alpinia oxyphyllafor leukaemia, Cupressus lusitanica, Argyreia speciosa (or Lettsomia nervosa), Aquilariaagallocha, Hypericum richeri, Grindelia camporum or squarrosa, Althaea officinalis,Argemone mexicana, Cinnamomum zeylanicum, Myroxylon balsamum, Saxifraga aizoides,Mahonia aquifolium, Pulmonaria angustifolia or officinalis, Bambusa arundinacea,Peucedanum ostruthium, Rubia cordifolia, tinctorium or peregrina, Draba aizoides,Campanula latifolia, Polygala senega, Smilax sarsaparilla or utilis, Citrullus colocynthis,Albizzia lebbek, Celastrus scadens, Myrica cerifera, Nepeta cataria, Taraxacum officinalis,Galphimia glauca, Adiantum capillus veneris, Drosera rotundifolia, or anglica, orintermedia, Annona squamosa, Thymus serpillum, Sysymbrium officinale, Larrea mexicana,Aralia racemosa, Actinidia chinensis, Crocus sativus, Buxus sempervirens, Viola tricolor,Sambucus nigra, Laurus nobilis, Tephorosia purpurea, Myristica fragrans and sebifera,Tabebuia impetiginosa, Larrea divaricata, Eclipta alba, Ailantus glandulosa, Rosmarinus290

officinalis, Thymus vulgaris, Hyssopus officinalis, Luffa operculata, Apium graveolens,Artemisia dracunculus, Crataegus oxyacantha or monogyna, Chondrus crispus, Panaxginseng, Ajuga reptans, Ajuga piramidalis, Tinospora cordifolia, Leucanthemopsis alpina,Emblica officinalis, Moringa pterygosperma, Eupatorium perfoliatum, or purpureum,Glycyrrhiza glabra, Hieracium pilosella, Morinda citrifolia, Xantoxilum fraxineum,Trifolium pratensae, Sutherlandia frutescens, Arctium lappa, Ulmus rubra, Rhodiola rosea,Rumex crispus, Boswellia serrata, Rheum palmatum or officinale, Echinacea purpurea,angustifolia or pallida, Astragalus membranaceus, Hypoxis hemerocallidea, Lycopodiumclavatum, Tribulus terrestris, Picramnia antidesma, Cassia angustifolia, Rhamnus sagradaor purshiana, Rhamnus frangula, Terminalia chebula, Ocimum basilicum, sanctum otenuiflorum, Capparis spinosa, Lonicera coprifolia, Cardamine pratensis, Carpinusbetulus, Carlina acaulis, Curcuma longa, Holarrhena antidysenterica, Lepidium meyenii,Stachys arvensis, Polygonum aviculare, Geranium robertianum, Myrtus communis,Melaleuca alternifoglia, Cinchona calisaya or succirubra, Azadirachta indica, Lepidiummeyenii, Calendula silvestris, Schinus molle, Ilex paraguariensis, Cassia occidentalis,Cynara scolymus, Phyllanthus orbicularis, Zingiber officinale, Goniothalamus species,Myroxylon balsamum or pereiraeThe importance of CEREALSIt is extremely important that cereals are wholemeal cereals.Of course, flour is the basic form to have them as pasta, bread, or polenta.Wheat is the most widespread cereal. Gluten is contained in its seeds in an ideal proportion, and itmakes it particularly suitable for rising and bread-making. There are two varieties of wheat: hardwheat (Triticum durum) and soft wheat (Triticum aestivum or vulgare). The percentage of aminoacids contained is about 13% (Triticum vulgare) and 12,5% (Triticum durum), but all 9 essentialamino acids are never present together. With the introduction of milling by steel wheels, that tookthe place of traditional grindstones, the large-scale production of white flour started. This flour isrefined, and has kept its energetic value, but not its nutritious value (vitamins), as it does not havethe outer layers of the grain (bran) nor the wheat germ (vitamin E).What happens is that very often companies try to add bran to white flour again, but the productobtained cannot be compared to true wholemeal flour: the true semolina has indeed a quite uniformamber colour, compared to these mixtures that are easy to recognize (characteristic inhomogeneouslook with brown parts that are darker or whiter).Other cereals: rice (amino acids: 6%), millet (amino acids: 11%), barley (amino acids: 11%), oat(amino acids: 12%), sweetcorn (amino acids: 9.5%), rye (amino acids: 16%), amaranth (aminoacids: 16%), emmer wheat (amino acids: 12%). The 9 ESSENTIAL AMINO ACIDS are NEVERpresent together.Common buckwheat (Fagopyrum esculentum) is not a cereal, but something different. It isparticularly rich in lysine (as LEGUMES) and tryptophan, and the amino acid percentage is about11%. It contains a lot of Iron, Magnesium and group B vitamins, vitamin B17 included. It must notbe eaten with cereals because ALL 9 ESSENTIAL AMINO ACIDS could be found together.Hippophae rhamnoides (Olivello spinoso) is rich of Lysine, as LEGUMES.Emmer wheat (Triticum spelta) does not have a high glycemic curve, contrary to other cereals, so itcan be used for people who need to avoid high glycemic peaks, such as for cancer or diabetespatients.291

Amaranth and rye are cereals. They have a high percentage of amino acids (16%), and they alsocontain lysine, an essential amino acid that is almost absent in other cereals. Therefore the risk is tosum up all 9 essential amino acids in case amaranth is eaten together with other cereals (e.g.: bread).Secale cereale (rye) and Amaranthus hypochondriacus (amaranth) are too rich in Lisin.Note: wholemeal pasta (emmer wheat, kamut, barley etc..), as it is wholemeal, releases starch, so,contrary to pasta made with hard wheat, it has to be carefully drained.The taste is stronger than the one of white pasta, to the point that, if you don’t want to lose thesubstances that you drain, you can keep them apart for an evening vegetable soup, for examplecooking some vegetables in bit of water with half bouillon cube, and mixing them with the drainedwater, until you get a cream. Many food substances are sold that try to integrate nutrition with alarge part of these cereals. You should choose wholemeal flour, without added substances.POTATOS : Hippocrates SoupFor one person use a 4-quart pot, assemble the following vegetables, then cover with distilled water:1 medium celery knob (or 3 to 4 stalks of celery), 1 medium parsley root (if available), garlic, 2small leeks (if not available, replace with 2 medium onions), 1,5 Ibs tomatoes or more, 2 mediumonions, and a little parsley.Do not peel any of these special soup vegetables; just wash and scrub them well and cut themcoarsely; simmer them slowly for 2 hours, then put them through a food mill in small portions; onlyfibers should be left. Vary the amount of water used for cooking according to taste and desiredconsistency. Keep well covered in refrigerator no longer than 2 days. Warm up as much as neededeach time.Potatos or CerealsPotatos or Cereals should be taken in adequate quantities (small portions), and only in case ofproven necessary (fever, excessive weight loss).It is advisable to exclude Sodium from the diet (Sodium chloride or sea salt).Among cereals it is advisable to eat emmer (70 grams for plate).NEVER mix cereals and potatos: Patients cannot eat potatos and cereals during the samemeal.NOTE: The glycemic curve, caused by the introduction of FRUIT and/or VEGETABLE, (and orCEREALS, or POTATOS) should be always under certain values. Some raw foods could be listedwith the specification of the amounts to be taken every hour as acceptable values of maximumglycemic curve tolerable for a diabetic patient.Only the doctor can establish the best associations among fruits and/or vegetables.1 liter of liquidized fresh fruit (grapes, fruits of the forest) contains about 800-900 kilocalories,equal to 750cc of milk, or 650 grams of meat or 10 eggs….Even the fresh fruit which we have is rich in energy:1 liter of juice from biologically grown apples is 500 kilocalories1 liter of juice from biologically grown cherries is 450 kilocalories292

1 liter of juice from biologically grown pears is 420 kilocalories1 liter of juice from biologically grown oranges is 400 kilocalories.3 units of FRUIT and/or VEGETABLE as ¼ LITER / 1 HOUR :UNITS of Juice (for Light glicemic Curve) :1/2 Orange1/2 Lemon1/2 Apple1/2 Pear1/2 Grapefruit1 Kiwi1 Pricklypear1 Plum1 Peach1 Pomegranate3 Aprocots15 Cherries60 grams of Grapes80 grams of Gooseberries100 grams of Blackberries100 grams of Mulberries140 grams of Raspberries180 grams of Bilberries180 grams of Whortleberries180 grams of Blueberries1/2 fetta of water Melon1/2 fetta of musk Melon100 grams of Carrot150 grams of Pepper150 grams of Onion150 grams of Leek250 grams of “italian Coste”250 grams of Turnip300 grams of Cabbage300 grams of Broccoli300 grams of Tomato300 grams of Spinach300 grams of Beet300 grams of Brussels sprout300 grams of Italian “Indivia”400 grams of Lettuce400 grams of Artichoke400 grams of Cauliflower400 grams of Italian “Cime di Rape”400 grams of Italian “Verze”400 grams of Celery500 grams of Radish600 grams of Courgette or Zucchini293

Food combinations (cereals + legumes)It is also important not to eat pasta (Triticum durum, vulgare, spelta) or Sweetcorn (Zea mays), orrice (Oryza sativa), or bread together with pulses, because doing so there is an integration of the 9essential amino-acids (the 8 contained in the cereals + the 8 contained in the pulses), with anutritional effect similar to the one obtained by eating meat (SEE chapter 1.b: Proteins)ALL the essential amino acids are: Valine, Isoleucin, Leucin, Lysine, Methionine, Histidine,Tryptophane, Phenylalanine, Treonine.LEGUMES contain a lot of energy, and, potentially, a lot of proteins. They contain a lot of proteinsonly together with food containing the missing amino acid (usually Methionine).Dangerous CEREALS and LEGUMESNever mix cereals and pulses (LEGUMES) at the same meal, because of the riskof adding together ALL 9 THE ESSENTIAL AMINO ACIDS (which has asimilar effect to eating meat, eggs, fish, cheese …..).Patients cannot eat legumes and cereals during the same meal.Cereals are preferable to legumes.Among cereals is advisable to eat emmer (70 grams for plate)It is advisable to exclude Sodium from the diet (Sodium chloride or sea salt).Some useful Spices to add to emmer organic Pasta (70 grams of “Farro” or “Kamut”).Only the doctor can establish (months – time: 3, 6, 12, 18….), if the patient eatLegumines and Cereals during the same meal and / or Fish1) Ematic value: total protein (from 6,0 grams / 100 ml to 6,2 grams / 100 ml), albumin,and other….)2) X-RAY tomography (TAC) images, or Magnetic Resonance Tomography (MRT)images without “ENHANCEMENT EFFECT” ( typical aspect of all malignant tumourswith peripheral “bordered” accumulations of “contrast” for“high density protein of thetumor), but “good internal perfusion” of the “contrast” (Iodine with X-Ray tomography,or Gadolinium with MRT)Pulses are allowed:Medicago sativa (alfalfa, lucerne), Glycine maxima (soya), Cicer arietinum (chick peas), Phaseolusvulgaris (beans), Vicia faba (broad beans), Lens esculenta (lentils), Pisum sativum (peas),),Ceratonia siliqua (carob), Colutea arborescens (Erba vescicaria), Trigonella foenum graecum(fenugreek), Galega officinalis (galega), Lotus corniculatus (five-finger), Glycirrhiza glabra (sweetroot), Lupinus albus (lupin), Melilotus officinalis (yellow melilot), Trifolium pratense, rubeus(clover), Anthyllis alpestris or vulneraria (kidney-vetch, lady’s-finger).294

FishPay attention to farmed fish because the feed comes from unsafe sources (for example - butcheredanimals): according to the author small-sized and salt-water fish should be chosen, possiblybelonging to species that tend to accumulate only small quantities of polluting substances (forexample: anchovies, needle-fish, skullcaps, pilchards, sardines, mackerel, etc...).Tuna, however, is considered to be a valid nutrient for neoplastic patients as well.Fish should be eaten only after the immunity cascade has begun, with a noticeable dimensionaldecrease in the tumour mass, given the possibility that the essential amino-acids found in fish couldbe assimilated by the tumour cells as well.The dangers of GM foodThus, those that are dangerous for health are only GM legumes, as they have ALL nine essentialamino acids, as we already know for alfalfa ( 745,967 ), for GM soya, GM peas, ( 1011, 2006 ), for GMclover ( 1066 ), and GM beans. People must know what happens if they use these as food, because theresult is a nutrition full of proteins, and not only of energy. This is particularly important for peoplewho have chronic-degenerative diseases (cancer, diabetes, arthrosis, osteoporosis, cardio-vasculardiseases, American obesity, etc). The hidden protein intake can nullify nutritional therapies basedon avoiding proteins (they are based on totally eliminating MILK, MEAT, EGGS, FISH andYEATS from the diet).The problem is similar also for GM CEREALS, that were recently introduced in our nutrition. Theycontain the missing amino acid, usually Lysine.At the moment, there are three GM cereals being produced and sold in the United States and in therest of the world: SWEETCORN, RICE, and WHEAT.Although many patients are very careful about food labels, at the moment we cannot exclude thefollowing facts, based on failed therapy in some cases where the diet was correct:1) Rice sold in Europe presumably contains Lysine in good quantities, as opposed to organic rice. Italso seems that some rice brands sold in Europe also contain the pesticide toxin Bacillusthuringiensis (SEE below).2) Some brands of GM sweetcorn have already been officially introduced in Europe, but we don’tknow whether they were enriched with all essential amino acids or not, nor how they weremodified. It seems that they were modified introducing Bacillus thuringiensis, a pesticide toxicsubstance.3) At least one fifth of Italian PASTA is made with wheat coming from abroad, usually fromAmerica (“Panorama” magazine, 2004-2005): no-one can exclude that American flower containsALL 9 ESSENTIAL AMINO ACIDS.It would be interesting to study the pasta imported from America to check the presence of:a) ALL 9 ESSENTIAL AMINO ACIDS, by comparison with certified organic wheat (organicwheat contains little or no Lysine).295

) Transgenic toxins (Bacillus thuringiensis).c) Transgenic viruses (SEE chap. 8), that are often used to make GM vegetables.The problem of WHEAT: the author expresses particular concern about wheat (Triticum durum),from which in Italy today we get both pasta and bread: patients suffering from cancer need a lot ofenergy (at least 2,000 kcal/per day) provided that it comes from food with no Vitamin B 12 andwithout ALL 9 Essential Amino Acids. That is NO animal product: Pasta, together with rice, is (orwas) the most suitable food for this. They have already started growing new varieties of wheat inthe USA, of the GM variety, the characteristics are not yet known. However it is feared that theymay have been enriched with Lysine as in American potatoes, American maize, and American rice.For this reason, the author expresses serious doubts on the introduction of cereals, pulses and othergenetically modified vegetables (often not even declared as such) onto the market that could containALL the ESSENTIAL AMINO ACIDS (9), thus effectively rendering Cancer no longer curable asdescribed in the present study.For example, it has been possible to trace from bibliographical data that the potato (previouslyconsidered a cure for tumors), is today absolutely counter-indicated, because the synthesis gene ofLysine has been inserted into it ( 689 ). This is an essential amino acid that the potato did not have,and a gene obtained from Amaranthus hypocondriacus (amaranth, tumbleweed) which is wellknown to be rich in this essential amino acid. The very same Lysine ( 685 ) has been introduced into alocal variety of potato in Israel, since 1992. In 1997, in the United States, human Casein wasintroduced into a North American variety of potato, thus making it complete with all the essentialamino acids ( 687 ). In 1998 Bacillus thuringiensis was transferred to potatoes by means of GMOtechnology, and these were fed to mice ( 1589 ) : the intestinal cells of these mice showeddegeneration phenomena and lesions in the microvillus on the surface of the intestinal space;hyperplasia was present in half of the cells and of several nuclei; the thin basal plate of the intestinewas damaged in various places; several damaged microvilli appeared with fragments containingendoplasmic reticulum; the Paneth cells had a high degree of activation and contained a highnumber of secretory granules. [note from the author of this site: the resulting picture reminded one,at least to some extent, of ileitis from rays, or “Baserga syndrome”, well known in the Marshallislands in 1954, where many civilians were exposed to food contaminated by radionuclides of alphaand beta emissions, coming from the fallout of nuclear explosions].The genetic threat from this experimentation is very little debated with regard to its real problem( 689 ).If the patient manages not to destroy all of his/her own reserves of proteins in muscles, maintainingan energetic physical program, with long walks and exercise suitable to maintain good muscle tonethroughout the patient’s whole active muscular structure, then the organism will begin to look forprotein reserves which are not essential, such as fatty tissue and above all, the neo plastic tissuesthemselves.But particular attention must also be paid to other transgenic variants (GM) of plants used for food,which, according to the author, can no longer be used in a cure against cancer, because such plantsusually come from abroad and furthermore have been prepared in laboratories in American,Canadian or Japanese industries and are therefore suspected of being carriers of transgenic viruses(with a risk of transgenic diseases); of lacking the important vitamins needed to fight tumors andperhaps of being carriers of substances which inhibit apoptosis in diseased cells (SEE below).It is because of this that the author expresses serious concern about the introduction on the marketof cereals, pulses and other genetically modified vegetables (often NOT declared) which could296

contain ALL the ESSENTIAL AMINO ACIDS (Valine, Isoleucin, Leucin, Lysine, Methionine,Histidine, Tryptophane, Phenylalanine, Treonine) thus effectively rendering cancer no longercurable using the treatment described in this work, a work which in its ideals links up to the oldtherapy of Dr. Gerson, extending it to many other curative plants such as Aloe arborescens, forexample.The author of this study thus maintains that if GMO are liberalized, there will be the most seriousenvironmental disaster ever seen, because there will no longer be any possibility of curing cancerwith Gerson's diet, or with other food programs as described in this study, which alone were able tocure between 70% and 90% of patients, provided that there was no Chemo-Therapy ( 749,750,969 ).NOT Sweetcorn (Zea mays): unfortunately it is a lost product, as it has a high transgenic pollutionrisk. Transgenic sweetcorn is dangerous both because of “Bacillus thuringiensis” (SEE chap. 2 and3) , because Retro-vurus (SEE chap. 8) and added Lysine ( 982 ) and/or Tryptophane.NOT Soya (Glycine maxima soya): it has a high trangenic risk, just like all of its byproducts, forexample Tofu (soya “cheese”). Soya GMO contains too many proteins and ALL 9 ESSENTIALAMINO-ACIDS, Bacillus thuringensis , and Retro-virus (SEE chap. 8)NOT Tofu (it’s soya “cheese”)NOT GM salmon : it contains transgenic viruses (SEE chapter 8 about transgenic viruses andcancer or Leukaemia).NOT Peas: transgenic risk ( 1011, 2006 ).NOT Beans : trasngenic risk.NOT Peanuts (Arachis hypogaea): transgenic risk297

Some Juicing tips offered previously by Dr. GersonFrom: “The Gerson therapy. The amazing juicing programme for cancer and other illnesses”, byCharlotte Gerson and Morton Walker, Thorsons ed, pp.: 113-125For the preparation of vegetable and fruit juices, Dr. Max Gerson recommended two machines: a separate triturator orgrinder and a separate press. One of his juicing tips was that all parts of the juice machine that come into contact withground foods should be made of stainless steel. Therapy exponents currently favour one machine in particular whichuses these two processes.Dr. Gerson required his recovering patients always to prepare fresh juices made from organic fruits and vegetables. Headvised them never to attempt to prepare sufficient juice for the whole day in the morning. Also, as another tipdiscussed at length in his original text, Dr. Gerson advises not to drink water because the full capacity of one’s stomachis needed for the juices and the Hippocrates special vegetable soup. Components in the soup are readily absorbedthrough the gastrointestinal mucosa. Water filling up the stomach tends to dilute the action of that organ’s gastric acidsand digestive enzymes.This capter gives a complete description of the types of juicing machines along with the juicing process. As comparedwith Dr. Gerson’s original text, here we provide much new information coming from those patients who have preparedtheir own juices at home and restored themselves to good health. A combination of the enzymatic effect of fresh, wholeorganic juices plus a therapeutic saltless diet with appropriate , limited, nutritional supplementation and the taking ofcoffee enemas – all assured means – results in renewed wellness that is long –lasting, natural, and safe. Juicing plantproduce and swallowing the result is the most delicious way to good health.Renew wellness by Drinking organic, Fresh-Made JuicesJuicing and imbibing such juice are integral aspects of the Gerson Therapy program. Unconditionally , the coauthorsreaffirm: For any ill individual as well as for someone in a state of good health, drinking fresh-made juices processedfrom organically grown fruits and vegetables frequently through each day is critical to renewing or maintainingwellness.An important note: While there are no federal standard for the commonly used combination term organically grown,it’usually refers to produce planted and grown without chemical pesticides, herbicides, or synthetic fertilizers, on farmlands and in groves, orchards, or vineyards that have been free of such chemicals for from three to seven years.Along with providing sufficient fluid intake, fresh juices furnish nearly all of the nutrients-vitamins, minerals, enzymes,phytochemicals, herbals, and other vital food substances, including even proteins – required for your body to heal itself.Juice drinking is even more important for healing degenerative diseases than eating the same nutrients held in wholefood. In fact, juices are food, of course, but in much more assimilable form for use by the gastrointestinal tract. Juicedrinking allows for better digestion and greater absorption. By a person’s conforming to the Gerson Therapy protocoland consuming thirteen 8-ounce glasses-about 104 ounces of juice daily – this vast amount of liquid plus threevegetarian meals offers the equivalent of between 17 and 20 pounds of food a day. Few people (possibly nobody) couldconsume that much solid edible material during usual waking hours. Drinking juices allows one to ingest massiveamounts of nourishment in a short time.Degenerative diseases often promote poor digestion for those persons victimized by them. Because of their intoxicationfrom malfunctioning organs, the presence of decreased gastric acids, digestive dysfunction overall, and other suchdifficulties directly connective with the body’s degenerations, such people are likely to suffer from the loss of appetiteand an inability to eat at all or to hold and assimilate even small quantities of food. (Such a discomforting condition isknown as cachexia).Yet degenerative disease patients who suffer in this way often are able to keep themselves nourished rather well merelyby drinking fresh made juices. The juiced nutrients are far more vital yo one’s body than the fiber contents of wholefoods. Nevertheless, solid foods must be added to the patient’s total intake.Juicing helped Dr. Gerson heal his patientsIn order to bring about healing for his many tubercular, cardiovascular, cancerous, diabetic, arthritic and other patientssuffering from degenerative diseases, Max Gerson, M.D., sought out new methods for overcoming their subclinicalmalnutrition. Even obese persons can lack nutrients. For each ill individual, juicing at home is how Dr. Gerson met the298

challenge. And it was a technique which proved valuable. The juices made from raw foods and drunk by these very sickpeople provided the easiest and most effective means of giving them the highest-quality nutrition. This unique methodof feeding that he developed during the approximately thirty-five year period from 1923 to 1958 produced the bestclinical results ever witnessed in medical practice by that midpoint in the twentieth century.Today, with the twenty-first century upon us, the coauthors are reluctant to make changes in a protocol that has beenextremely effective for treating, reversing, or sending into near-permanent remission degenerative diseases of all types.These are the kinds of serious illnesses for which pharmaceutical medicine has had very little to offer..During the course of his thirty years of active clinical practice, however, Dr. Gerson did change his protocolconsiderably. He repeatedly altered what the physician described as his “juice prescriptions” in response to his patients’blood test results, healing reaction responses, allergies, weight variations, and other metabolic conditions.The physiological responses of severely damaged or weakened individuals often required him to change themedications and juices on an almost daily basis, especially during their first weeks of following the Gerson Therapy.That is the situation for current patients as well.Questions and answers about drinking juicesDrinking juices begets large numbers of questions for which there are few answers. For instance, we wonder at butcannot completely answer some of the fallowing queries from those utilizing the Gerson Therapy:When or how regularly should one drink the juices ?Dr. Gerson advised that an ill individual should take 8 ounces at least once every hour, but it’s not uncommon to findsuch a regimen difficult to accomplish.What’s to be done as a solution or compromise for being unable to follow the program exactly ? Drink as much as youcan, but keep trying to ingest more. In this situation for juicing and drinking, more is better.How much juice should you drink ?As mentioned, attempt to consume 104 ounces of fresh organic juice in twenty-four hours.How soon after actually performing the juicing is the best time to drink down the juice ? Unquestionably, the answer as“At once” !It is acceptable to store the juice for future drinking ? The direct and uncompromising answer is “No !”. But let’s face it– if you work at a distance from home and can’t lug around a 70-pound juicing machine, taking apple/carrot juicesalong with you in thermos-type storage containers or 8-ounce mason jars filled to the top is not all that bad. Do it if it’sthe only way you’ll be getting your daily allotment of organic juices. Never keep or take along green juices (made fromsalad greens) for future ingestion because they oxidize quickly and lose their value.Do we know what fruits and vegetables may best be combined or are incompatible ? Our observation is that almost allof plant produce is compatible, although Dr. Gerson urged the use of specific combinations of carrot and apple, carrotonly, and juice made from various greens. Avoid other juiced produce.At which section of one’s gastrointestinal tract is juice absorption best ?The entire length of the intestinal tract (23 feet or 7 meters from the top opening of the stomach to the anus) goes towork on enzymes in juices and takes them into the bloodstream. But not too much nutrient absorption takes place in thestomach, large intestine, and rectum.Are the kidneys flushed more effectively if the recommended juices are consumed ?Yes, physiological testing has shown that juice enzymes are cleansing agents – sometimes truly diuretic in nature. Youcan test this concept yourself by juicing large, white asparagus and drinking the product. Drinking celery juice is nearlyas good a diuretic too. By drinking juices like these, you’ll then urinate a lot, resulting in well-flushed kidneys and aswabbed-out urinary tract.Some personal rules about juicingNow we offer a bit of knowledge for you to assimilate. Since the therapeutic enzymes in freshly produced plant juicesdo oxidize out of existence and into free radical destruction by exposure to the oxygen in air for any prolonged period,we must offer two parts of one definite rule to follow.299

If at all possible, try to freshly prepare each of your 8-ounce glasses of juice and drink them down immediately. This isespecially important for the very ill patient.In the morning, do not prepare all juices for drinking during the day in order to store them for later use, because beforethe day’s end you’ll probably be swallowing deficient juice with many nutrients missing.Types (6) of Juicing devicesPartly on an intuitive belief but mostly observing results in his patients, Dr. Gerson presumed that the method of juiceextraction decidedly affected the concentration of nutrients his patient took into their bodies.Forty years after his death, we know from analyses of juices produced by each type of yuicing device that somemachines are better than others for the production of quality drinking liquids. Also, the clinical results experienced bypatients using each type of juicer provide further support for Dr. Gerson’s original presumptions.Although there are six types of juicers manufactured, which we will describe briefly, our preference focuses on oneparticular product type. We will cite the lesser machines first and move on the best kind to use this therapy.Below are descriptions of the forms of juicing mechanisms which do produce vegetable and fruit juices but, comparedto the sixth one that we prefer, a few of them hardly provide anything really drinkable in acceptable qualities andquantities.1) Masticating JuicersMasticators, as the term describes, chew up the vegetables or fruits and extract their juices in one step. The juice qualityis fairly good, but the amount of vegetable or fruit pulp remaining is excessive with some of the plant enzymes beingleft behind in so much pulp. While the juice produced by masticators is richer in nutrients than that from centrifugaljuicers (see below), it is less nourishing than what’s acquired from the type of triturator or grinder/press that we prefer.Also, a masticating juicer heats up inside its grinding chamber, which tends to damage the enzymatic quality of theresulting juice.2) Centrifugal JuicersBy far the most common and least expensive of the juice extractors, centrifugal juicers are also the least desirable forfulfilling requirements of a patient on the Gerson Therapy.A centrifugal jucer works by pushing the vegetable or fruit part against a rotating disk whose teeth reduce it to pulp.Centrifugal force then throws the plant pulp against a basket screen through which the juice is strained, while the pulpremains behind. Such a mechanism sounds just right, but there are problems with the centrifugal procedure.1) The produce does not get ground finely enough, particularly in the green leafy sort of vegetable.2) The centrifugal force is less effective than the pressing action of other juicers in extracting juice. Such inadequatepressing causes minerals and phytochemicals (vitamins) in the pulp to remain in the pulp; thus, the juice that’s renderedis lower in healing enzymes and other nutrients.3) Dr Gerson said about centrifugal juicers, “When the grinding wheel rotates against a resistance with insufficientaccess of air, positive electricity is produced and induces negative electricity on the surrounding wall. The exchange ofpositive and negative (ions) kills the oxidizing enzymes and renders the juice deficient.” He went on to say that hispatients who utilized centrifugal juicers did not experience healing successes with their self-administration of histherapy.Among the centrifugal juicers, present an enzyme deficiency problem. In contrast, centrifugal juicers with angled-walljuicer baskets (currently popular because of vast amounts of promotion and advertising), don’t have such a seriousproblem. Even so, centrifugal juicers offer an overall lack of nutrients and a reduced quantity of juice when comparedwith other types. As with the masticator juice machines, the centrifugal types are moderately priced.3) Wheatgrass JuicersBeing small and highly specialized devices, wheatgrass juicers are designed specifically to extract the chlorophyll-ladenjuice of wheatgrass.The Gerson Therapy does not use wheatgrass inasmuch as most patients find it to be extremely harsh for assimilation bythe stomach. Besides, the desirable components in wheatgrass are already found in the Gerson green leaf juice, which isrecommended for ingestion two to four times every day and is much easier on the digestive tract.4) Citrus JuicersUsed for orange or grapefruit juicing exclusively, a citrus juice apparatus is a reamer-type device that cannot be used forany other type of fruit or vegetable. One should never use a citrus juicer that presses the skin.300

5) Blender / LiquefiersCertain liquefying machines are powerful blenders and not really yuicers at all. They grind the produce into a fine pulp,but they don’t extract its juice. Since there is no reduction of bulk with a blender/liquefier, to derive the nutrientsequivalent to those in 104 ounces of freshly produced organic plant juice, a person would need to ingest an alarmingquantity of produce. According to our calculations, it would amount to at least 6 pounds of carrots, 8 pounds of apples,and four heads of lettuce every day, in addition to eating three regular meals. That’s much too much bulk food foranyone to take into one’s digestive tract in a twenty-four-hour period, expecially very ill people with little appetite anddisturbed digestive systems.Yet any juicer is better than no juicer at all. Even the less effective type of juice machine will furnish more nutrientsthan might be consumed in the equivalent quantity of produce.But don’t let price be the governing factor in choosing your juicing device. At the Gerson Institute, observations haverepeatedly been made that some patients rigorously following the Gerson Therapy by use of a lower-cost centrifugaljuicer have failed to experience either reductions in tumour masses or healing reactions even after many weeks on theprogram.However, when they switched to the grinder/press juicer we’re about to describe, their healing reactions occurredrapidly, and many saw dramatic improvements in their conditions. Be advised, therefore, that the choice of anappropriate juicer may be a life-or-death matter.Among the various kinds of juice machines marketed today, we prefer only a couple of brands coming from the oneparticular extractor type to which we have alluded. We’ll now discuss this sixth kind of juicer.6) The Triturator (Grinder) / Press combinationPossessing a grinder or triturator for turning vegetables and fruits into a fine, juicy pulp and a hydraulic press forextracting the juice’s enzymes from this pulp, the particular juicer – a triturator (grinder)/press combination machine –is the most acceptable choice for people suffering from serious degenerative diseases, especially for cancer patients. It isthe juicer type of our preference. After grinding (the definition of “trituration”) juice is extracted from vegetable or fruitpulp by being squeezed under high pressure of as much as 2,000 pounds per square inch (PSI).Dr. Gerson recommended this type of machine above all others and suggested to his patients that they mix the pulp ofdifferent vegetables or fruits together thoroughly before pressing to enhance the extraction of certain nutrients. Such acourse of action is possible only with a juicer that separates the grinding and pressing functions. Research indicates thatDr. Gerson’s selection of a grinder (triturator)/press type of machine produces as much as fifty times higher amounts ofcertain essential nutrients such as the lycopene in ripe tomatoes or the proanthocyanidin in the seed membranes ofgrapes, both of which have proven anticancer qualities. Taken from a trituratur / press type of device, the vegetable orfruit juice is much fuller-bodies than that produced by other kinds of juicers. Moreover, it is free of pulp and furnishesabout a 35 percent greater quantity of juice from the same amount of raw produce that might have been put throughother juicing machines. Green leafy vegetables offer up even more quantity when processed by a triturator (grinder) /press extractor.How to juice without undergoing a nervous breakdownWhatever the juicing apparatus one uses, to produce various juices without undergoing a nervous breakdown,particularly during the beginning weeks of the Gerson Therapy program, we have some helpful hints to offer.The patient or the patient’s support person will be spending three to five hours of each waking day in front of the juicerproducing the healing liquids that impart nourishment to body parts, tissues, and cells which have been lacking them.(That’s one of the reasons the patient’s immune system is performing in a lesser manner than it’s supposed to).So, here is our series of what we anticipate will be helpful suggestions:Place the machine in a location that’s pleasant to view –in front of a picture window, next to the sound of music, closeto favourite photographs, and so on.Since wash water for the juicer will be required regularly, have the machine’s location be near the sink.Because the juice goes in undesirable directions on occasion, it’s a good practice to place the device on a large cafeteriatray to save your countertop from excessive washing.It’s not uncommon for vegetable pulp (especially carrots and green leafy items) to end up on the ceiling – especiallyduring the first weeks of the juicing regimen. But this occurrence may be minimized by holding the flat of your handover the open-mounth tube into which the produce is fed. Without letting your fingers get ground with the vegetables,this action will stop produce splatters and feedback.301

Wear a large apron to protect your clothing from such splatters too.Figure in advance how many carrots, apples, greens, peppers, chard, red cabbage, and other produce will be required foreach day’s juicing. Then scrub and wash them in advance, cut them into smaller pieces, and bag them in sufficientquantity for each session of juicing.Consider making your clothes washer into a giant “salad spinner” by putting greens for the day into a mesh bag andrunning them through the “damp dry” cycle on the washer for twenty seconds to get rid of the excess water.Use small pillowcases wrapped inside a large garbage bag to hold all of the day’s greens and keep them from gettinglimp before use.Purchase vegetables and fruits several times each week to ensure their freshness. Don’t let them sit around for an entireweek before they are turned into juice. This suggestion relates to green leafy items in particular. Still, you may need asecond refrigerator.Of course, acquire only organically grown produce, and at all costs avoid plant life that’s come in contact withchemicals such as pesticides and herbicides. Chemicals on fruits and vegetables are a major reason that degenerativediseases of all types cause disability and death. Degenerations are known to some members of every family in the formof pathological symptoms.Inasmuch as some organic produce becomes unavailable when it goes out of season (such as apples), it’s advantageousto arrange in advance with your produce distributor for you or the support person to buy and pay for a couple ofmonths’ supply (but greens won’t keep), to be held in the distributor’s cooler until needed by the patient.If you can afford it, install your own walk-in cooler for the advance storage of out-of-season produce.After each juicing, try to disassemble the machine and wash its separate parts. It’s tempting to do this after every thirdor fourth juicing, but be aware that bacteria or other unwelcome microrganisms may lodge on the food debris.Use of a sink disposal unit and a sink sprayer hose makes it easier to clean the juicing apparatus.For a press-type juicer, rinse off pulp from the pressing cloths, wring them out, place in bags, and store them in thefreezer. Such an action keeps them microrganism-free.Once a week, boil the pressing cloths in purified water.If, after some time, the juice taste is “off” or “pulp explosion” occur too frequently, the fault probably will lie withoverused cloths. It’s time to replace them because the cloths’ pores become clogged with fibers from the pulped juice.If work or travel make it difficult to produce fresh juices during the day, here is the procedure to follow. Acquire aglass-lined or stainless steel vacuum bottle (thermos) and fill it with juice completely to avoid excess air exposure.Avoid storing green juices, but carrot/apple juice may be stored.302

Chapter 17:Absolute incompatibility of Phyto-Therapy withChemo-TherapyAccording to the author, any use, even in limited, of Chemo-Therapy (Chemo-Therapy) is totallycounter-indicated by the use of phyto-therapeutics, given the ample demonstration in medicalhistory of its failure in anti-neoplastic therapy.In future it will be necessary to consider the legal situation of the doctor who treats his patient withfront line Chemo-Therapy, without having previously tried to induce Immuno-Therapy with Phytomedicines.No patient who has already been subjected to Chemo-Therapy should undergo the long, complexand demanding therapies described here, because the effects of Chemo-Therapy are such that theyremove all possibility of treatment, especially concerning Immuno-Therapy (SEE chapter 4).However, the doctor is allowed to attempt Immuno-Therapy for humanitarian purposes, bearing inmind the absence of any certainty as regards to actually curing the patient, due to the considerabledamage suffered because of the previous sessions of Chemo-Therapy: this also applies in the caseof low dosage Chemo-Therapy given by mouth, as is done in anti-neoplastic therapies which aretoday defined as “alternative” because they use Somatostatina-Octreotide, etc…In fact, often Chemo-Therapy is carried out at the patient’s home, with the prescription of pills,capsules, tablets (5 mg Alkeran®, 50 mg Endoxan Asta®, 25, 50 or 100 mg Lastet capsules®, 5 mgLeukeran®, 2 mg Linfolysin®, 2.5 mg Methotrexate® [note: the use of the latter is also allowed forthe treatment of rheumatoid arthritis, according to the Italian Pharmaceutical Reference book], 2 mgMyleran®, 2 mg Puretinol®, 50 or 100 mg Vepesid®).In any case, taking these tablets orally has extremely serious consequences, because the immune system of the gastrointestinaltract is the most developed of all, given the antigenic load to which the organism is constantly exposed: in factthe cutaneous surface is only 2 square meters, the pulmonary surface is 80 square meters, whilst the gastro-intestinalsurface reaches 300 square meters. The gastro-intestinal immune system, being extremely developed, is the reason forwhich many phyto-therapy medicines are given orally, with the intent of inducing a specific or generic immunostimulationtowards particular natural antigens found in certain types of plant (SEE chapter 9), but this also explains itsextreme vulnerability to Chemo-Therapy, because the latter leads towards a gradual alteration of the intestinal mucoustissues (especially the colon) caused by the death of the lymphocytes present in the mesenteric lymph nodes, in thePeyer Plates and the Lamina propria, etc. Such alteration determines not only a gradual alteration of the functioning ofthe lymphatic tissue present on the intestinal mucous, but also a gradual paralysis of the lympho-immune structuressituated in other parts of the body, with their consequent functional depletion.This DECLARATION may therefore be summed up as follows:Phyto-Therapy, being based mainly on Immuno-Therapy, that is on the activation of theImmune Cascade of the lymphocytes, should not be carried out on patients who are beingtreated with Chemo-Therapy, or who have been in the past, because of the high improbability oftherapeutic success. However, the doctor is free to try Immuno-Therapy, for humanitarianpurposes.Any doctor who is responsible for immuno-therapeutic treatments CANNOT assume theresponsibility for following patients who are being treated with Chemo-Therapy, or any othertherapy which debilitates the immune defenses, such as External Radio-Therapy, or theprolonged use of cortisones. However, the doctor is allowed in any case to attempt Immuno-Therapy for humanitarian purposes, bearing in mind the absence of any certainty as regards toactually curing the patient, considering the heavy damage caused by the previous sessions ofChemo-Therapy.303

Any form of Chemo-Therapy causes irreparable damage to the physical condition of whoeverexposes themselves to the action of these poisons called "cyto-toxic medicines".The Hippocratic oath declares that it is forbidden to administer "poison" to a patient, even if thatpatient himself asks for it (see the Hippocratic Oath).These poisons ("cyto-toxic medicines"), enter the bloodstream by means of injections and/orintravenous drips, or by indirect absorption via the stomach or intestinal mucous.This type of treatment is different from surgery or radiotherapy, which concentrate their effects onspecific points of the body (targeted therapy).Chemo-therapy is used in hospitals when it is possible that cancer cells may be present in otherparts of the body other than the primary tumor.But rarely does Chemo-Therapy guarantee a survival period of at least 5 years, calledinappropriately "the treatment period".Rarely can we talk about "remission": bibliographical data report success in less than 1% in cases ofcancer of the pancreas, 3% in cases of cancer of the liver, 7% in cases of cancer of the intestine.....There are 60-70 cyto-toxic medicines on sale worldwide.Some of these poisons cause fewer problems than others, such as: insomnia, tiredness, diarrhoea,alopecia, stomatitis, leukopenia, platelet penia, anaemia, nausea, vomiting ....These are the immediate side effects, well known because they are visibly recognisable.Rarely do we talk about the more serious and longer lasting effects, the consequences of whichdeeply deteriorate the life of a patient and the course of the illness. They render useless any therapybased on the immune-stimulation of natural killer lymphocytes, on apoptotic activity anddetoxification using extracts of medical plants.These serious and irreversible damages, which are rarely discussed, are the following:1) A serious, stable and lasting reduction in the number of particular types and subtypes of whiteblood cells, which are indispensable for specific immune response against a tumor.2) Somatic type cellular mutation, with the onset of other secondary tumors and/or metastasis.3) Germinal type cellular mutation (testicles or ovaries), with the onset of sterility, miscarriages orthe birth of deformed children from parents who have survived Chemo-Therapy or cancer.4) Acceleration rather than decrease in the growth of the tumor, with the tumor acquiring crossresistanceto other poisons (glycoproteic membrane pump).Chemo-Therapy (CH.T.) is not feasible in any way.These aim to safeguard the patient’s bone marrow for the concurrent basic Immuno-Therapy.Chemo-Therapy is completely contraindicated in any kind of association with Immuno-Therapy.In fact, Chemo-Therapy is extremely depletive especially towards the lymphocytes, which havebeen recognized as being able to identify and destroy the tumoral masses through specific antineoplasticImmuno-Therapy (SEE chap. 4). According to the author, it can be asserted that it willonly be the patient’s immune defenses which solve the neoplastic pathology, allowing him to makea complete recovery from the cancer. The surgical operation, external radiation, the use ofMonoclonal Antibodies (MoAbs) in pre-targeting with radiactive isotopes must be consideredmerely as support techniques or methods, able to eliminate a certain amount of the primitivetumoral mass and its metastasis, bearing in mind that none of these factors can be considered themain reason for the patient’s complete recovery from the tumor: the possible and effective recoveryof the patient from the tumor depends solely on the ability of his immune defenses to recognize and304

destroy the tumor itself in a selective and radical manner (SEE chapter 4). The Immuno-Therapytherefore denies that Chemo-Therapy has any value in treating and curing the tumor.General failure of Chemo-Therapy against nearly all forms of tumor: Chemo-Therapy reduces thetumoral mass, but at the great expense of causing severe damage to all the patient’s organs and1, 2, 7, 9, 12, 15, 18, 19, 23, 26, 31, 32, 33, 35, 36, 42, 44, 46, 50, 53, 54, 57, 60, 64, 65, 67, 68, 70, 72, 77, 80, 81, 82,tissues, SEE table 2(84, 88, 89, 90, 91, 92, 93, 95, 99, 100, 102, 104, 105, 109, 107, 110, 111, 113, 115, 117, 118, 121, 125, 127, 128, 133, 135, 137, 139, 140, 149, 150,151, 152, 160, 162, 164, 166, 167 169,170, 171, 172, 173, 178, 180, 181, 183, ,1035,1067-1073 ): It determines medullar deficiency(with resulting infections and drop in the body’s immune defense against the tumor itself), hepaticinsufficiency and kidney failure, possible development of pulmonary fibrosis with respiratoryproblems, damage to the heart and to the blood vessels, leukaemia and secondary cancers in avariable percentage. In any case, the neoplasia nearly always recurs, with the tumoral cellsparticularly resistant to other Chemo-therapeutic medicines, in subsequent cycles of second andthird line Chemo-Therapy, until finally it is defined, quite inappropriately, “rescue Chemo-Therapy”: in reality, it is a final and destructive Chemo-Therapy, carried out with chemotherapeuticmedicines of different kinds, which are never able to save the patient, and even less tomake him reach an effective recovery…”305

Chapter 17.1.:the failure of the Chemo-TherapyIn 1975, Prof. Hardin Jones, University of California, proved for the first time, on a large-scalestudy that lasted 23 years, that cancer patients refusing to undergo Surgery, Radiotherapy andChemotherapy (on a free food regime, without following a particolar diet) survived on average 3-4VOLTE DI PIù, whereas patients that were treated with standard medication (Surgery,Radiotherapy and Chemotherapy).Since then, this observation has been confirmed many times in medical literature, e.g. for breastcancer: survived on average 12 and a half years, whereas patients that were treated with standardmedication (Surgery, Radiotherapy and Chemotherapy), died on average within 3 years ( 1067 ) [Thenatural history of breast carcinoma in the elderly: implications for screening and treatment, Cancer 2004; 100(9),pp.:1807-1813, http://www.mednat.org/cancro/MORGAN_%20cancer_no_chemio.pdf ]; in consideration of theaforementioned, multi-centre studies on clinical experimentation on poor women affected by breastcancer, published in 2003-2004, concerning results obtained through various combinations ofChemotherapy, report totally inconclusive results: e.g. periods of approx. 5 months free from illnessand an average of 15 months survival time ( 1068 ) [Multicentre, phase II study evaluating capecitabinemonotherapy in patients with anthracycline and taxane-pretreated metastatic breast cancer, Eur. J.Cancer, 2004; 40(4),PP:536-542], or in the so-called Salvage Chemotherapy with average survival periods free fromillness of only 8 months, with a average response period of 4 months, and progression of the illnesswithin 5 months ( 1069 )[Full dose paclitaxel plus vinorelbine as salvage chemotherapy anthracycline-resistantadvanced breast cancer: a phase II study, J.Chemother. 2003,15(6),pp.:607-612], or with survival periods freefrom progression of the illness of approx, 3 years with an average of about 1 year survival( 1070 )[Phase II study of docetaxel in combination with epirubicin an protracted venous infusion 5-fluorouracil (ETF) inpatients with recurrent or metastatic breast cancer. A Yorkshire breast cancer research group study, Br.J.Cancer, 2004,90(11),pp.:2131-2134], or with an average survival period of 2 years ( 1071 )[Capecitabine plus paclitaxel asfront-line combination therapy for metastatic breast cancer: a multicenter phase II study, J.Clin.Oncol.2004,22(12),pp:2321-2327], or with a survival period free from progression of illness of 8-10 months, with anaverage survival time of 18-19 months ( 1072 ) [Phase III study of intravenous vinorelbine in combination withepirubicin versus epirubicin alone in patients with advanced breast cancer: a Scandinavian Breast Group Trial,J.Clin.Oncol.2004, 22(12),pp.:2313-2320]. Lastly, the “compassionate” use of Chemotherapy prescribedorally: “…an open-label, non randomized, compassionate-use study was carried…”( 1073 )[Oralcapecitabine in anthracycline and taxane-pretreated advanced/metastatic breast cancer, Acta Oncol.,2004,43(2),pp.:186-189].Again, in 1990, Prof. Ulrich Abel, of the University of Heidelberg asserted: ”…althoughchemotherapy drugs produce a “response”, i.e. they bring about a reduction in the tumour mass,this reduction does not prolong the patience’s survival; what’s more, cancer returns moreaggressive than before, in that chemotherapy favours the growth of resistant tumour clones.Furthemore Chemo seriously damages the body’s defence, namely the immune system, very oftenkidneys and the liver….”(Chemothrapy of advanced epithelial cancer: a critical survey. Hippokrates Verlag,Stuttgart, 1990; Healing Journal, No.1-2, Vol.7, 1990).According to the data presented by Prof. Abel, patients treated with Chemotherapy presentsignificantly poorer results, in terms of survival, in respect to patients treated with conventionalmedicine, gruped together and compared per type and stadium of tumour.Prof. Abel states: “…an impartial and balanced analysis of medical literature shows an almost nilrate of therapeutic success when employing conventional treatments for the cure of advanced forms306

of solid tumours ….” (Chemothrapy of advanced epithelial cancer: a critical survey.Stuttgart, 1990; Healing Journal, No.1-2, Vol.7, 1990).Hippokrates Verlag,In 1991, oncologist Albert Braverman wrote: “…no type of solid tumour that was consideredincurable in 1975 is curable today. Many oncologists recommend Chemotherapy for virtually anyform of tumour, with expectations that the systematic failure does not discourage …”When Chemotherapy is usefulA Board of the World Health Organization declared that Chemotherapy is useful only in 1,5% (onepoint five percent) of cases.According to a review of 1.500 scientific publications issued by Prof. Jones of the University ofCalifornia, the above percentage of success rises to 2%.Far more optimistic is the Gerson Institute, that reaches an estimate percentage of success (patientswho survived five years from diagnosis) of around 15%, with a substantial failure however, of 85%of cases treated, a failure that rises to 93% in the case of intestinal tumours, to 97% in the case oftumours of the liver, to 99% failure if tumour of the pancreas ( 749 ) [Gerson C.: La Terapia Gerson.Macroedizioni,2002].The Dubious Validity of Official StatisticsOfficial statistics reporting cases of therapeutic success of present standard treatments are by nomeans founded ( 1197-1204 ). In 1985, Prof John Cairns, University of Harvard, published a devastatingcritical essay on Scientific American: “ … apart from rare types of leukaemia, it is not possible tonote any significant change in the incidence of death rate in patients with cancer following thelarge-scale use of Chemotherapy. There is no scientific evidence that Chemotherapy can actuallycure the various types of cancer that nowadays afflict human society…”.In 1987, 42 USA Congressmen ask to have a clear picture on alternative therapies that could beused for the treatment of cancer. Among other things, worthy of note is the fact that not evenSurgery has been approved as a means for treating cancer, as no study with the traditional controlgroup has ever been carried out to evaluate long-term results. Nor has Chemotherapy ever beenapproved, but it is only in a phase of experimentation that has been lasting for 50 years.In essence:A good “Response Incidence” only means that the tumour appears reduced in volume, but thatdoesn’t mean that it has been defeated.“Response” means: reduction in the volume of the tumour mass already recognized.“Response Incidence”: is the percentage of patients in which a diminishing of the tumour massalready known can be observed, during the months that follow Chemo-Therapy.“Response Duration”: means how long the reduction in the tumour mass lasts.“Complete Response”: means that the tumour mass can no longer be observed during diagnosticinvestigations.“Partial Response”: reduction by about 50% of the tumour mass.307

ECRI (Emergency Care Research Institute) studies assert that the “Response Incidence”, i.e. thereduction of the tumour mass following Chemotherapy, cannot be correlated to the “Prolonging ofthe patient’s survival”.“Remission” does not absolutely mean “longer survival”.Medical literature concerning Chemo-Therapy never uses terms such as: “healing”or “quality of life”.Vice-versa, in medical literature on Intensive Chemo-Therapy and Bone-marrow Transplant in thecase of cancer with metastasis, statistics published very often refer to results that appear far betterthan what they actually are.For example, statistics do not report about those patients that die as a consequence of the onset ofinfections that occur immediately after bone marrow transplant, that did engraft, with completefailure, therefore, of the transplant.These patients are referred to by research scientists with the term “premature decease”.For example, the incidence of premature deceases in woman with breast metastasis was reported in31 case studies published in the years from 1984 to 1994. The average registered was 10% instudies carried out from 1992 to 1994. Vice-versa this percentage rises to 17% when consideringonly the case studies that refer to 1994.In other cases, patients that died due to infection do not result to have died because of cancer butappear among the number of “healed” patients.Cost of ChemotherapyIt is believed that the cost of Chemotherapy for the Italian Government adds up to about 0,4 billionEuros per year.308

Chap.17.2.:Official statistics of Chemo-TherapyWe will now analyse survival times of patients with different malignant tumours after undergoingChemo-Therapy:(IV degree Astrocytomas, Head and Neck Cancers, small cell and non-small cell Cancer of the lung,small-cell Bronchial Carcinoma, Breast Cancer, Cancer of the Stomach, Cancer of the Pancreas,Kidney Cancer, Cancer of the Prostate, Ovarian Cancer, Cancer of the Uterus, Colorectal Cancer,acute and chronic myelogenous Leukemias, acute and chronic lymphatic Leukemias, MultipleMyeloma, Hodgkin’s lymphoma/ NON-Hodgkin’s lymphoma)Brain TumoursPercentage of survival after five years, in the case of fourth degree astrocytomas (multiformglioblastomas) is a mere 4-5%. .( 1035 ) [McLendon R: Cancer, 98 (8), pp.: 1745-1748, 2003 ;http://www.mednat.org/cancro/Allegato%202_Lendon_Alperin.pdf].This latter scientific article states: “In 30 years, this rate has by no means improved…).Head and Neck CancersMuch research work has shown that post-surgical Chemotherapy does not prolong life in respect topatients that are not treated with Chemotherapy, however on a free food regime and no particulardiet ( 60,435 ) [Stell P.M.: Br. J. Cancer, vol. 61, pp. 779-787, 1990 ;http://www.mednat.org/cancro/Allegato%203_Stell_Rawson.pdf ] ; [Chalmers T. in: De Vita: "Cancro, principi epratica dell'oncologia", Lippincott and Co, Philadelphia, 4.a edizione, pp 235-241, 1993 ].Some researches – out of twenty-three studies on pre-operatory and post-operatory Chemotherapy –demonstrated that there is no difference between groups treated with Chemotherapy and groups nottreated (without any particular diet to follow ( 72,74,98,195,397, 449 ) [Tannock I.F.: J.Clin. Oncol. , Vol. 6,pp.1337-1387, 1984];[Clark J.R.: Seminars in Oncology, vol. 15, Suppl. 3, pp. 35-44, 1988];[Dodion P.: Raven Press,New York, pp. 525-547, 1986];[Choski A.J.: Seminars in Oncology, vol. 15, Suppl. 3, pp. 45-49, 1998];[Schantz S.P. :in : De Vita V. "Cancro, principi e pratica dell'oncologia", Lippincott and Co, Philadelphia, 4 a. edizione, pp. 574-630,1993];[Jacobs C.: J. Clin. Oncol., vol. 8 pp. 838-847, 1990 ;http://www.mednat.org/cancro/Allegato%204_%20Charlotte%20Jacobs.pdf ].Finally, according to a recent study (2004) ( 1340 ), which considered over 7,500 patients, only 2.5%were still alive 5 years after initiating Chemotherapy (this work is available in PDF format at:http://www.mednat.org/cancro/MORGAN.PDF ).Non-small Cell Lung CancerThere are no evident indications of an advanced stage being influenced by Chemotherapy alone,concerning cases of advanced stage non-small cell lung carcinoma ( 2 ) [Abel U.: Biomed andPharmacother, vol. 46, 1992, aggiorn. 1995, pp. 439-452] ; ( 241 )[Lad T.E.: Immediate versus postponed combination309

chemotherapy (CAMP) for unresectable Non-Small Cell Lung Cancer: a randomized trial, Cancer Treatment Reports,Vol. 65, No.11-12, 1981 ; http://www.mednat.org/cancro/Allegato%205_Thomas%20E.%20Lad.pdf ].In the case of non-small cell bronchial carcinoma, some studies show an improvement in survivalthat is not, however, statistically significant being so limited that they do not justify the use of toxictherapies like Chemo.Authors of extended research work all share the same view on this statement: ( 16,39,158,259, 296, 361 )[Bakowski M.T.: Cancer Treatments Reviews, vol.10, pp. 159-172, 1983 ;http://www.mednat.org/cancro/Allegato%206_Marie%20T.%20Bakowski.pdf ];[Mitrou P.S.: Atemw.-Lungenkrhk., vol.12, pp. 544-549, 1986];[Rankin E.M.: Slevin and Staquet, Studi randomizzati del cancro: un inventario critico perlocazioni, Raven Press, New York, pp. 447-492, 1986];[Liu R.J.: Seminars in Oncol., vol. 20, pp. 296-301,1993];[Hansen: J.Clin. Oncol., vol. 5, pp. 1711-1712, 1987];[Browen M.: in: Rosenthal S.: "Supporto medico delpaziente con cancro", W.B. Saunders Co, Philadelphia, pp. 200-215, 1987]Even recently, survival percentages have not changed: a Japanese work (2000) showed that 24% of41 patients undergoing Chemotherapy with Radiotherapy were still alive after 3 years and 10% after5 years ( 1326 ). [ Japan Clinical Oncology Group Study 9306, Journal of Clinical Oncology, Vol. 20, No.3, 2002,pages: 797-803].Another Japanese study (2004) demonstrated that only 2 patients out 70 patients treated withChemotherapy and Radiotherapy responded completely to the therapy. Two years after thetreatment 33% of patients were still alive ( 1327 ) [Yukito Ichinose: Uracil/Tegafur plus Cisplatin withconcurrent Radioterapy for locally advanced Non-Small-Cell Lung Cancer: a Multi-institutional Phase II Trial,Clinical Cancer Research, Vol. 10, 2004, pp.: 4369-4373 ; http://www.mednat.org/cancro/Yukito%20Ichinose.pdf].The same results were obtained by a Dutch study (2004), which considered 57 patients undergoingChemotherapy without Radiotherapy: 50% of patients were still alive after about 4 months, but afterone year only 32% were alive and in December 2002, i.e. 2 years and a half after the onset of thetherapy, all patients were dead ( 1328 ) [F.M. Wachters: Phase II Study of docetaxel and carboplatin as secondlinetreatment in NSCLC, Lung Cancer, 2004, Vol. 45, pp.255-262 ; http://www.mednat.org/cancro/Wachters.pdf ].Small-cell Bronchial CarcinomaIn 1986, George et al. wrote “…. with only a modest percentage of remissions, the incapability oflong-term palliatives (contained action of symptoms), and a very modest number of survivors after2-3 years, even in patients treated at the initial stage of the illness, no treatment with Chemo can beconsidered a standard in dealing with small-cell lung carcinoma …” ( 127 ) [George TK, in : Cancer, vol.58, pp. 1193-1198, 1986 ; http://www.mednat.org/cancro/Allegato%207_T.%20K.%20George.pdf ].During the following ten years, Klastersky (1995) summarized the most important studies that hadbeen carried out: “….. recently, a number of different chemotherapy regimes have been tried, inthe hope of improving the results by increasing the intensity of the dose. All of these efforts, fromthe extreme (Chemotherapy with bone-marrow transplant) to the simplest (doubling of doses), havefailed. No significant result has been obtained by increasing the chemotherapy doses in thetreatment of small-cell bronchial carcinoma, nor has any improvement been noted through thecombination of single agents…” ( 223 ) [Klastersky J., in Seminars in Oncology, vol. 22, Suppl. 2, pp. 11-12,1995].Kokron (1982) observed: “…in the control group that was not treated with Chemotherapy (howeveron a free food regime, with no particular diet, n.d.t.) evident advantages were due to the quality oflife owing to the absence of side-effects tied to chemo-therapy and to the briefness of the terminalphase of the illness…” ( 232 ) [Kokron O., in : Onkologie , vol. 5, pp. 56-59, 1982].310

According to a 2004 study ( 1340 ), which involved about 28,000 patients (some suffering from smallcell cancer and others from non-small cell cancer), only 2% of them were still alive 5 years afterstarting Chemotherapy (the work is available in PDF format:http://www.mednat.org/cancro/MORGAN.PDF .Breast cancerThere are many scientific works which demonstrate that Chemotherapy is essentially useless in thetreatment of the breast cancer ( 71, 117, 183, 344, 373, 481 ).[Chlebowski R.T.: A decade of breast cancer clinical investigation: results as reported in the program/proceedings ofthe American Society of Clinical Oncology, Journal of Clinical Oncology, Vol. 12, No.9, 1994, pp.: 1789-1795 ;http://www.mednat.org/cancro/Allegato%208_Chlebowski.pdf ].[A prospective randomized trial comparing Epirubicin monochemotherapy to two Fluorouracil, Cyclophosphamide,and Epirubicin regimens differing in Epirubicin dose in advanced breast cancer patients, Journal of Clinical Oncology,vol.9, No.2, 1991, pp.: 305-312 ;http://www.mednat.org/cancro/Allegato%209_French%20Epirubicin%20Study%20Group.pdf ].[Hoogstraten B.: Combination chemotherapy and adriamycin in patients with advanced breast cancer, a SouthwestOncology Group Study, Cancer, 38, pp.. 13-20, 1976 ; http://www.mednat.org/cancro/Allegato%2010_Hoogstraten.pdf[Petru E.: No relevant influence on overall survival time in patients with metastatic breast cancer undergoingcombination chemotherapy, J.Cancer Res.Clin.Oncol., 1988, No: 114, pp.: 183-185 ;http://www.mednat.org/cancro/Allegato%2011_Petru.pdf ];[Walters R.S.: Arandomized trial of two dosage schedules of mitomycin C in advanced breast carcinoma, Cancer,1992,Vol. 69, No.2, pp.:476-481; http://www.mednat.org/cancro/Allegato%2012_Walters.pdf ].As far as far the use of different combinations of Chemotherapies is concerned, a number ofmulticentric experimental studies conducted on women affected by breast cancer and publishedbetween 2003-2004 showed inconsistent results: disease-free time of about 5 months and mediansurvival time of 15 months ( 1068 ) [Multicentre, phase II study evaluating capecitabine monotherapy in patientswith anthracycline and taxane-pretreated metastatic breast cancer, Eur. J.Cancer, 2004; 40(4), PP:536-542 ;http://www.mednat.org/cancro/Allegato%2013_Fumoleau.pdf]; in case of the so-known “Salvagechemotherapy”, the disease-free median survival time was only 8 months with an average responsetime of 4 months and a disease progression within 5 months ( 1069 ); disease progression-free survivaltime 3 years with median survival time of 2 years ( 1071 ); disease progression-free survival time of 8-10 months with median survival time of 18-19 months ( 1072 ). Finally, the “compassionate” use ofChemotherapy given by mouth: “…An open-label, non randomized, compassionate-use study wascarried…” ( 1073 ).( 1070 )[Phase II study of docetaxel in combination with epirubicin an protracted venous infusion 5-fluorouracil (ETF) inpatients with recurrent or metastatic breast cancer. A Yorkshire breast cancer research group study, Br.J.Cancer, 2004,90(11),pp.:2131-2134; http://www.mednat.org/cancro/Allegato%2014_Humphreys.pdf],According to doctor Ulich Abel, there is no direct evidence that Chemotherapy prolongs survivaltime; this should be noted because all women affected by breast cancer undergo Chemotherapybefore and after the surgical intervention ( 1306 ).In March 1996, Dr. Nelson Erlick, Director of the ECRI (Emergency Care Research Institute),carried out an extended analysis of the case studies published by the medical literature on breastcancer in the years prior to 1994. 1.500 scientific research works were studied.311

On the basis of all the available data, the following resulted:1) In the initial phase Intensive Chemotherapy and Bone-marrow transplant give ahigher “Response Incidence” compared to the standard Chemotherapy. In other words:the tumour mass diminishes (“Incidence of Response”). But, this “Response” does notlast long and cancer soon after starts to advance one again;2) Standard Chemo-therapy offers patients with breast cancer metastasis a longer “Durationof Response” (i.e. the number of months during which the reduction of tumour masslasts longer), and furthermore more patients survive for a year compared to those treatedwith Intensive Chemotherapy and Bone-marrow Transplant;3) Scientific research on Intensive Chemotherapy and Bone-marrow transplant has not yetidentified any sub-group of population in which this treatment can guarantee a period ofnon-progression of cancer that is major to that referred to control groups.Up until the present day, medical literature has never declared that Intensive Chemotherapy andBone-marrow Transplant may actually heal/cure anyone from breast cancer. IntensiveChemotherapy and Bone-marrow Transplant produce an income of 150-200 thousand Euro-Dollarsfor each bone-marrow transplant. The latter without considering the high percentage of deceasesduring the months that follow bone-marrow transplant, owing to fatal infections caused by germs,that occur in patients that are momentarily deprived of adequate immune defences after heavyChemotherapy and the lack of active bone marrow, that takes time to engraft, notwithstanding thetransplant performed in the previous weeks.As far as this is concerned, it is important to notice that in the Wall Street Journal of 17 November1994, in an article on the front page about politic pressure on insurance companies, so that they paidfor bone marrow transplantation in case of advanced stage breast cancer, the experts gave totallynegative reports about this sort of approach.As far as early breast cancers are concerned, Philip Day in his famous book “Cancer: Why We’reStill Dying to Know the Truth” recounts (pages 20-21) the incredible discovery of Doctor IrwinBross of Roswell Memorial Park Institute in New York:“… If a woman is diagnosed with early breast cancer, i.e. without metastasis, a simple scientific datum should beknown. When a pathologist diagnoses a lesion such as “an early breast cancer”, in the majority of cases the pathologistmakes a mistakes because actually it is not a breast cancer. Most women are affected by a tumour similar to a cancerwhen seen under an illuminated microscope. It is possible that this tumour will not metastasize, which happens in caseof a real cancer. The first controlled clinical trial regarding adjuvant therapies in the treatment of the breast cancer wasconducted in my department. Doctor Lesile Blumenson and I made a surprising discovery: more than half patients had atumour but it seemingly looked rather like a benign lesion. Our discovery did not arouse much interest amongprofessional doctors. They would never accept the idea to admit the scientific truth as at that time the therapy consistedin the radical mastectomy. Admitting the truth could have led some women – whose breast had been removed becauseof a wrong diagnosis - to undertake legal proceedings against those incompetent doctors. Doctors from National CancerInstitute – furious – did not allow us to continue the research. They probably succeeded in covering up our discoveryand stopping other publications. Breast cancer and cancer of the prostate have the same statistical results: when thefunctions of the two sexual organs decrease, cells often become abnormal and look like tumour cells. The Journal of theAmerican Medical Association reported surprisingly high survival times for patients affected from cancer of theprostate which were not treated. This demonstrates that 7 cancers out of 8 were NOT actually cancers. Therefore, thereis no reason for women to get into panic when the word “cancer” is pronounced. It is the panic that makes them easyvictims…”312

According to a recent study (2004) ( 1340 ), which considered over 42,000 patients, only 1.5% werestill alive after 5 years from the first Chemotherapy cycle (this work is available in PDF format at:www.mednat.org/cancro/MORGAN.PDF).On the contrary, in women suffering from early mammary cancer –i.e. without systematicmetastasis to other organs or systems, except for axillary or inner mammary lymph nodes – afterundergoing Surgery only (with or without emptying of the axillary lymph nodes but withoutRadiotherapy or hormonal therapy), the local percentage of disease-free survived patients after 5years from the operation is 50% if not in menopause and 70% if already in menopause ( 1751 ).With Ormonal Therapy, after Surgery, the percentage of disease-free survived patients after 5 yearsfrom the operation (if not in menopause) increases to about 70% ( 1751 )…With Radiotherapy, this percentage further increases to about 90%. (Franco Bistolfi, SEE : “LaCronoBioDose nella RadioTerapia Esterna” ; dal libro “La Terapia dei Tumori con Gadolinio 159in Risonanza Magnetica Nucleare”, Italo Svevo Editore, ( 1755 )http://www.mednat.org/cancro/ALLEGATO%2044.pdf )With Chemotherapy (before or after undergoing Surgery) the percentage of disease-free survivalcases after 5 years decreases to about 75% for these patients, even in the case of new-generationChemotherapy such as Taxanes ( 1752 )Cancer of the StomachKingston evaluated the effectiveness of chemotherapy drugs versus placebo (however on a freefood regime, with no particular diet), in patients presenting non-operable gastric carcinoma. Thegroup of 95 patients that underwent Chemotherapy showed an average survival time more or lessequal to survival of patients on placebo ( 221 ) [Kingston R.D.: Clinical Oncology, vol. 4, pp. 55-69, 1978].The unanimous evaluation of many other authors is that medical literature does not give any proofof prolonging life through Chemotherapy in the case of stomach carcinoma ( 178,277,300,358 ) [MoertelCG.: Cancer, vol. 36, pp. 675-682, 1975];[Queiber W.: Onkologie, vol. 9, pp. 319-331, 1986];[Hockey M.S.: Slevin andStaquet, Raven Press, New York, pp. 221-240, 1986];[Mc Donald: Seminars in Oncology, vol. 15, Suppl. 3, pp. 42-49,1988].Twelve randomized studies, that compared post-surgical Chemotherapy to control patients (on afree food regime, with no particular diet) have demonstrated the more or less same time of survival.( 7,210,171,154 ).[Alexander H.L. .in:DeVita: Cancro, principi e pratica dell'oncologia, Lippincott and Co., Philadelphia,1993, 4.a ediz.];[Kelsen D.: Seminars in Oncol., vol. 18, pp. 543-559, 1991];[Hermans J.: J.Clin.Oncol. Vol. 11, pp.1441-1447, 1993];[Hallissey M.T.: The Lancet, vol. 343, pp. 1309-1312, 1994].During the last 10 years the situation has not improved. According to a Japanese study (2004)which considered about 500 patients from 1985 to 1997, 8% were still alive 2 years after beginningChemotherapy and only 2% after 5 years. ( 1317 ) [Yoshida M., Jpn J. Clin. Oncol. 2004, 34, pages: 654-9,FREE full text article at: http://www.jjco.oupjournals.org ]Other recent works demonstrate that Complete responses were achieved only in few cases; anAmerican research (2005) involving 43 patients affected by Cancer of the stomach and theesophagus showed only one Complete Response and 5 Partial Responses; after 6 months 50% of thepatients were alive, after 15 months 20% and after 2 years 12% ( 1318 ) [Enzinger PC. : A phase II trial ofirinotecan in patients with previously untreated advanced esophageal and gastric adenocarcinoma, Dig. Dis. Sci. 2005,50, pp.: 2218-2223; http://www.mednat.org/cancro/Enzinger.pdf ].313

According to the results of an Italian study (2006) involving 52 patients, 50% were still alive oneyear after the first Chemotherapy cycle but only 3 cases of Complete Response and 15 cases ofPartial Response were observed. We are waiting to know the percentage of patients alive after 2 and5 years ( 1319 ) [Felici A.: Bi-weekly chemotherapy with cisplatin, epirubicin, folinic acid and 5-fluiorouracilcontinuous infusion plus g-csf in advanced gastric cancer: a multicentric phase II study, Cancer Chemother.Pharmacol., 2006, 57, pp.: 59-64 ; http://www.mednat.org/cancro/Felici.pdf ].According to a study conducted in Korea, only one Complete Response and 13 Partial responseswere observed out of 30 patients undergoing Chemotherapy; median survival time for all patientswas 11 months. ( 1320 ). [Lee SH: Br. J. Cancer, 2004, 91, pages: 18-22].Another Korean study (2005) considered 43 patients undergoing Chemotherapy from January 2002to November 2002. Also the results of this study showed the slow decrease of surviving patients:about 40% of them 9 months after the beginning of the therapy, 20% after 14 months, then about18% after about 20 months and following less than 5% 2 years and a half after the firstChemotherapy ( 1324 )[Do-Youn: Docetaxel + 5-Fluorouracil + Cisplatin 3 day combination chemotherapy as afirst-line treatment in patients with unresectable Gastric Cancer, Japanes Journal Clin. Oncol., 2005, 35, pp.: 380-385;http://www.mednat.org/cancro/Do-Youn%20Oh.pdf ] .Another Swiss study (2004) showed that only one Complete Response wasachieved out of 52patients; 50% were still alive after 9 months, about 24% after 18 months, 20% after 20 months, 18%after 24-30 months and about 10% after 2 years. Survival percentages after 4 years are not knownyet ( 1323 ) [Roth AD: 5-Fluorouracil as protracted continuous intravenous infusion can be added to full-dosedocetaxel (Taxotere)-cisplatin in advanced gastric carcinoma: a phase I-II trial, Ann. Oncol. 2004, 15, pp.: 759-764;http://www.mednat.org/cancro/Roth.pdf].Another Korean research conducted in 2002 showed that only one Complete Response and no lessthan 19 Partial Reponses were achieved out of 35 patients receiving Chemotherapy from 1999 to2001; but the percentage of alive patients was 50% after 10 months, going down then to 20% after18 months. Survival percentages after 5 years were not published ( 1325 ) [Eun Kyung Cho: Epirubicin,Cisplatin, and Protracted venous infusion of 5-Fluorouracil for advanced gastric carcinoma, Journal Korean Med. Sci.,2002, 17, pp.. 348-52 ; http://www.mednat.org/cancro/Eun%20Kyung.pdf]..Finally, according to a recent study (2004) ( 1340 ), which considered over 5,000 patients with cancerof the stomach, only 0.7% were still alive 5 years after initiating Chemotherapy. On the contrary,out of 2,500 patients suffering from cancer of the esophagus, about 5% of them were still alive 5years after the first Chemotherapy cycle (work available in PDF format at:www.mednat.org/cancro/MORGAN.PDF).314

Cancer of the PancreasThe average time of survival is 3 months in patients that undergo Chemotherapy, whereas in controlpatients (on a free food regime however, and no particular diet), that have not undergoneChemotherapy, the average time of survival is approx. 4 months ( 118 ) [Frey C., Cancer, vol. 47, pp. 27-31,1981]. With Chemotherapy response results of over 30% have been reached (reduction of thetumour mass) ( 38,285,321,401 ) [Scheithauer W.: Tumor Diagnostik and Therapie, vol. 5, pp. 44-48, 1984; O’Connel:Seminars in Oncol., vol. 3, pp. 1032-1039, 1985;Meyer: Tumor Diagnostic and Therapie, vol. 8, pp. 54-58,1987;Brennan: .in:DeVita "Cancro, principi e pratica dell'oncologia", Lippincott and Co, Philadelphia, 4 a. edizione,pp. 849-882, 1993], but the survival period of time, compared to patients NOT treated withChemotherapy (likewise on a free food regime and no particular diet) does not change.Even considering more recent studies, the results do not change; for example, in 2006, using newchemotherapeutic agents such as Gemcitabine in association with Docetaxel, only 3 out of 43German patients demonstrated a Complete Remission; only 6 patients in all were still alive just oneyear after starting the therapy…but it is also known that the survival time after 2 and 5 yearsdecreases further ( 1309 ). [Ridwelski K.: Eur. Pharmacol., 2006, 32, pages: 297-302].Another study, which was conducted in 2005, considered 46 patients receiving Gemcitabine inassociation with 5 Fluorine-Uracile (5 F-U); the median disease-free survival time was only 3months and a half. About 75 patients died already one year after initiating the therapy. Also in thiscase data on survival time at 2-5 years are not available ( 1310 ). [Santasusana JM: Clin. Transl. Oncol. 2005,7, 493-498]According to a research carried out by the European Organisation for Research and Treatment ofCancer Gastrointestinal Group, at one year the survival rate is about 30% but with percentages of10% at 16 months and about 1-2% at 2 years ( 1311 ); [Lutz MP.: J. Clin. Oncol., 2005, 23, pages: 9250-6, Fulltext article at http://www.jco.org ]Rates of a further research are: 30% one year after initiating the therapy, 10% at about 18 monthsand about 2% at more than 2 years ( 1312 ). [Ko A:, J. Clin. Oncol. 2006, 24, pages 379-385].Better results were not reached even using microembolization and infusion of Cisplatin,Mitoxantrone and Mitomycin. Out of 265 cases treated in Germany between 1995 and 2005, 42-85% of patients were still alive one year after initiating the therapy, but the survival rate fell downto 20% after about 2 years and 10% after 4 years and settled at 5% after 5-6 years ( 1313 ) [K. Aigner:Celiac axis infusion and microembolization for advanced stage III/IV pancreatic cancer – a phase II study on 265cases, Anticancer Research, 25, pp.: 4407-4412, 2005 ;http://www.mednat.org/cancro/Allegato%2016_Karl%20R.%20Aigner.pdf ].Another research showed only one case of Complete Response and 2 of Partial Responses out of 68treated patients; the median survival time was 8 months, in particular the median survival time wasabout 6 months in patients with hepatic metastasis and about 9 months in patients without. In caseof peritoneal carcinomatosis, the median survival time was 7 months and a half, as against 9 monthsin patients without peritoneal carcinosis. Percentages of patients alive after 2 and 5 years are notavailable. But the study revealed that only one Complete Response and 3 Partial Responses wereachieved 54 months (4 years and a half) after initiating the therapy ( 1314 ) [Oman M.: Phase I/II trial ofintraperitoneal 5-Fluorouracil with and without intravenous vasopressin in non-resectable pancreas cancer, CancerChemother. Pharmacol., 2005, 56, pp. 603-609; http://www.mednat.org/cancro/Oman.pdfAccording to the results of another study involving 565 patients, the average disease-free survival315

time following Chemotherapy was only 4 months ( 1315 ). [Oettle H.: Ann. Oncol., 2005, 16, pages: 1639-1645, full text article at: http://www.annonc.oupjournals.org ] .Chemotherapy given by mouth did not produce better results: a study conducted in 2005 on 58patients treated with Rubitecan by mouth showed a survival time of 17% after 6 months but thispercentage falls to 9% already after one year ( 1321 ).Finally, another study conducted in 2004 demonstrated that only 20% of 48 patients treated by theNorth Central Cancer Treatment Group, USA, were still alive 9 months after starting the therapy.This percentage settled in the following months but it slowly decreased reaching 10% at the end ofthe study, i.e. after 2 years. We are waiting to know the percentage of patients alive after 5 years.( 1322 ).Instead, according to the results of a 2004 study ( 1340 ) involving over 5,000 patients, none of themwas alive 5 years after the first Chemotherapy (work available in PDF format at:www.mednat.org/cancro/MORGAN.PDF ).( 1737 ) [F. Di Costanzo : Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: arandomised phase II trial of the Italian oncology group for clinical research (GOIRC), British Journal of Cancer, No.93, pp. 185-189, 2005 ; http://www.mednat.org/cancro/Allegato%2017_F%20Di%20Costanzo.pdf ].Kidney cancerSurvival after two years from diagnosis is notoriously considered an anedoctal case, or with verylow survival percentages two years after the diagnosis (10-20%), if underwent chemotherapy( 1174,1175 ) [Gattinoni L.: Renal cancer treatment: a review of the literature, Tumori, 2003, 89(5), pp.: 476-484;Flaningan RC.: Metastatic renal cell carcinoma, Curr. Treat. Options Oncol. 2003, 4(5), pp.: 385-390].According to the results of a 2004 study ( 1340 ) involving about 6,000 patients, none of them wasalive 5 years after the first Chemotherapy (work available in PDF format at:www.mednat.org/cancro/MORGAN.PDF ).Cancer of the ProstateOn the 4 th November 1995, the scientific magazine The Lancet announces “…. 90% of cases ofprostate cancer never become clinically significant. The percentage of survival at 10 years amongpatients that had never received any treatment (either Surgery, or Radiotherapy, or Chemotherapy,or Hormonetherapy) was 91,5% against 77% of patients that underwent Radiotherapy…”.Comment of the author on the latter work published: Radiotherapy, as is known, destroys even thelocal defences, first of all the lymph nodes near the tumour, that abound in Natural-KillerLymphocytes, unfortunately extremely sensitive to radiations.Once again The Lancet, on 9 th December 1995, comes down heavily with the shock announcement:“…. radical surgery in the treatment of prostate cancer, manages only to spread the illness:monitoring 14 consecutive surgical operations, tumour cells that came from the prostate after theoperation were discovered in the blood stream of 12 patients. In those same patients no tumourcells were revealed in their blood stream before the operation took place….”316

According to the results of a 2004 study ( 1340 ) involving about 32,000 patients, none of them wasalive 5 years after initiating Chemotherapy (work available in PDF format at:www.mednat.org/cancro/MORGAN.PDF ).Ovarian Cancer101 women treated with a standard dose of “Cisplatine” showed the same period of survival asother 306 women treated instead with higher doses of “Cisplatine” ( 22,78 )[Bella M.: Abstract No. 706, in:Proc. Amer. Soc. Clin. Oncol., vol.11, pp.223, 1992] [Colombo N.: Abstract No. 614, in: Proc. Amer. Soc. Clin.Oncology, vol. 12, pp 255, 1993].Other studies confirm these results ( 81,329,330 ) [Conte P.F.: Abstract No. 880, in: Proc. Amer. Soc. Clin. Oncol.12, pp 273, 1993];[Ozols R.F, “Journal of Clinical Oncology”, Vol. 5, pp 641-647, 1987.];[ Ozols R.F.: Seminars inOncol., vol. 21, Suppl. 2, pp. 1-9, 1994].According to the results of a 2004 study ( 1340 ) involving about 4,200 patients, only 9% of patientswere still alive 5 years after initiating Chemotherapy (work available in PDF format at:www.mednat.org/cancro/MORGAN.PDF ).Cancer of the Uterus and EndometriumIn the case of metastasis cured with different combinations of chemotherapy drugs it is possible tohave a partial response percentage of the tumour of over 40%, but according to randomized studiesthis does not result in any prolonging of survival time. ( 31,186,327,455,492,) [Williams, C.J.: Raven Press, NewYork, pp. 417-446, 1986];[ Thigpen J.T.: Cancer, Vol. 60, pp. 2104-2116, 1987];[Hoskins WJ.in:DeVita:Cancro,principi e pratica dell'oncologia, Lippincott and Co, Philadelphia, 4.a edizione, pp. 1125-1152, 1993]; [Omura G.A.:Seminars in Oncol. Vol. 21,pp. 54-62, 1994];[Bonomi P.: J.Clin.Oncol., vol.3, pp. 1079-1085, 1985].In actual fact, in an extended study on 260 women in class IIb and IV, the combination ofChemotherapy and Radiotherapy proved to be even worse that Radiotherapy aloneM.H.: J.Clin. Oncol., Vol. 13, pp. 444-451, 1995 ;http://www.mednat.org/cancro/Allegato%2019_M.H.N.%20Tattersall.pdf].( 450 ) [TattersallAccording to the results of a 2004 study ( 1340 ) involving about 6,000 patients, none of them wasalive 5 years after the first Chemotherapy cycle. On the contrary, out of 2,500 patients sufferingfrom cancer of the cervix, about 12% of them were still alive 5 years after the first Chemotherapycycle (work available in PDF format at: www.mednat.org/cancro/MORGAN.PDF ).Colorectal CancerAccording to Nicholls ( 317 ) [Nicholls J.: in : Slevin and Staquet, Studi randomizzati del cancro: un inventariocritico per locazioni, Raven Press, New York, pp. 241-271, 1986] and Kane (204) [Kane M.J.: Seminars inOncology, vol. 18, pp. 421-442, 1991], the groups of patients not treated with Chemotherapy (buthowever on a free food regime, with no particular dietary restrictions), showed a major survivaltime compared to those patients that had undergone Chemotherapy.Even results obtained on 1523 patients, through hepatic arterial infusion chemotherapy, do not showan advantage in survival and, in contrast with the actual aim of these studies, even present anincrease in liver metastasis. ( 301,429, 485 ) [Soybel D.L.: Current Problems in Cancer, vol. 11, pp. 257-356,317

1987];[Weber W.: SAKK Anticancer Research, Vol. 13, pp. 1839-1840, 1993];[Moertel CG.: The New Engl. J. Med.,vol. 330, pp. 1136-1142, 1994].( 175 ) [Hine K.R.: Prospective randomised trial of early cytotoxic therapy for recurrent colorectal carcinoma detectedby serum CEA, Gut 25, pp.: 682-688, 1984 ; http://www.mednat.org/cancro/Allegato%2020_HINE.pdf ].Today the situation is not better. According to the results of an American study (2005) considering110 patients, only a Partial remission was achieved. The average survival time for all patients was 6months. More impressing was the drop in the number of disease progression-free patients (20%),which settled at 15% after 4 months and fell down to less than 5% 7-8 after initiating the therapy;the reported graph shows the slow but inexorable decrease of alive patients at 5, 10, 15 and 20months, with a final survival percentage of 10% after 18 months ( 1316 ).Finally, according to a recent study (2004) ( 1340 ), which considered over 30,000 patients affected bycolorectal cancer, only 1-3% of them were still alive 5 years after initiating Chemotherapy (thiswork is available in PDF format at: www.mednat.org/cancro/MORGAN.PDF ).Chronic Lymphocytic LeukaemiaIn a recent Polish study carried out on 229 patients who underwent chemotherapy, median survival(50%) for this disease is about 3-4 years, with the survival curve becoming slightly more stable inthe following years, with 8-9 year survival values of 30% for patients older than 65, and of 15-20%for adult patients younger than 65.( 1176 ) [T. Robak: The effect of subsequent therapies in patients with chroniclymphocytic leukaemia previously treated with prednisone and either cladribine or chlorambucil, Haematologica, 90,pp.: 994-996, 2005].In another recent, 10-year long work, 78 patients out of a total of 134 initial patients weresubsequently brought to the second stage of therapy, as they were still considered to be able tocontinue chemotherapy. Progression-free survival turned out to be lower than 3-4 years for morethan 75% of the 78 patients. Most of the 56 patients that were thought not to be able to continueclinical trials with the other 78 patients were excluded for the following reasons: hepatitis B virusinfection, Listeria monocytogenes infection, Zoster virus infection, persistent cytopenia,autoimmune hemolytic anemia, non-hematologic neoplasia, cerebral hemorrhage, persistently hightransaminase levels.( 1177 ) [F.R.Mauro: Fludarabine + prednisone + alfa-interferon followed or not by alfainterferonmaintenance therapy for previously untreated patients with chronic lymphocytic leucemia: long term resultsof a randomized study, Haematologica 88(12), pp.1348-1355, 2003]Note: according to the author of this work, dr. Giuseppe Nacci, this sort of exclusions fromchemotherapy treatment protocols are very common and tend to alter the final results.Acute Lymphoblastic Leukaemia in AdultsRecent works regarding life-saving chemotherapy for patients with primarily refractory or relapsedAcute Lymphoblastic Leukaemia carried out on 135 adults show that survival percentages tend tolinearize only after the first year from chemotherapy, with survival percentages lower than 20%.After 24 months, the percentage of patients still alive is lower than 10%.( 1178 ) [Camera A.: GIMELAALL –Rescue 97: a salvage strategy for primary refractory or relapsed adult acute lymphoblastic leucemia,Haematologica, 89(2), pp.145-155, 2004. http://www.haematologica.org ]318

Acute Lymphoblastic Leukaemia in ChildrenIf treated with chemotherapy, Acute Lymphoblastic Leukaemia in Children has a less dramaticprognosis compared to adults. Indeed, recent studies carried out in 1998 on 2038 children (a verywide sample) show variable survival percentages between 42% and 66.8%, 10-12 years afterchemotherapy, with a stabilization of the mortality curve around the fifth-sixth year after treatmentwith chemotherapy.( 1179 ) [R. Consolini: Clinical relevance of CD10 expression in childhood ALL, Haematologica83, pp.: 967-973, 1998]Note: as chemotherapy is notoriously ineffective for most tumours, we wonder why it seems to beso effective in Acute Lymphoblastic Leukaemia. You should keep in mind that many drugs canerroneously give haematological values similar to Acute Lymphocytic Leukaemia, Hodgkin’sLymphoma or Non-Hodgkin’s Lymphoma. The patient’s immune response to germs or viruses (e.g.Mononucleosis) can also erroneously lead to a diagnosis of tumour. (SEE further).Chronic Myelogenous LeukaemiaThe following reported data have been obtained from 1084 patients who underwent chemotherapy;almost all of them had bone marrow stem cell transplant. In comparison with Acute MyelogenousLeukaemia, the median survival is better: about 60% of patients are still alive after 24 months andthe survival curve tends to stabilize on slightly lower values in the following years. The situation forpatients with Chronic Myelogenous Leukaemia in the progressive phase is different: only 50% ofpatients are still alive after 12 months. The percentage drops to 35% after 24 months and thenstabilizes around 30%. ( 1180 ) [De Souza: Validation of the EBMT risk score in chronic myeloid leucemia in Braziland allogeneic transplant outcome, Haematologica, 90, pp.: 232-237, 2005.http://www.mednat.org/cancro/De%20Souza.pdf]Acute Myelogenous LeukaemiaA recent study of 2004 carried out on 621 elderly patients (older than 60) who underwentchemotherapy shows that the median survival (50%) is just 5-7 months. With an aggressivechemotherapy, less than 10% were still alive after 20 months; on the contrary, with a conservativeapproach (low-dose chemotherapy), about 20% of patients were still alive after 20 months. Thisfigure dropped to 10% after another 20 months. Both curves drop to less than 2-5% of survivors inthe following months. ( 1181 ) [Pulsioni A.: Survival of elderly patients with acute myeloid leukaemia,Haematologica, 89, pp.: 296-303, 2004; http://www.mednat.org/cancro/Pulsoni.pdf] .In another recent study of 2004, carried out on 258 elderly patients with Acute MyelogenousLeukaemia who underwent chemotherapy with stem cell self-transplant, median survival (50%)goes up to just 8 months. After 24 months, about 23-24% of all patients are still alive. Then thispercentage drops after 36 months and 48 months (4 years), when it seems that it finally stabilizes atabout 10% of survivors. ( 1182 ) [Oriol A.: Feasibility and results of autologous stem cell transplantation in de novo319

acute myeloid leukemia in patients over 60 years old. Results of the CETLAM AML-99 protocol, Haematologica, 89,pp.: 791-800, 2004; [http://www.mednat.org/cancro/Oriol.pdf] .Multiple MyelomaAbout 25% of patients survive five years after treatment with chemotherapy, less than 5% are stillalive after 10 years. ( 1183 ) [Kenneth C. Anderson: Management of Multiple Myeloma Today, Seminars inHematology, vol. 36, No.1, suppl.3, 1999 http://www.mednat.org/cancro/Allegato%2021_Anderson.pdf ].However, another study of 2000 ( 1367 ) based on a treatment randomization for Stage-1 MultipleMyeloma showed no benefits from chemotherapy compared to absence of treatment.Last, a recent work of 2004 ( 1340 ) carried out on about 2700 patients shows that no-one of thepatients was still alive five years after the beginning of chemotherapy.(http://www.mednat.org/cancro/MORGAN.PDF )Hodgkin’s LymphomaA recent work of 2003 studied 97 patients who underwent chemotherapy, radiotherapy and stemcell transplant, in a time span of 18 years: from 1982 to 2000. In patients with chemoresistantLymphoma, median survival (50%) is only two years, with the survival curve stabilizing at 30%five years after treatment. However, in patients with chemosensitive Lymphoma the survival curvegoes down slowly and stabilizes in a very good way during the sixth year, with a percentage ofsurvivors of 60% remaining the same in the ten following years. It is thought that the survival curvedoes not tend to further change.( 1184 ) [P.L. Zinzani: High-dose therapy with autologous transplantation forHodgkin’s disease: the Bologna experience, Haematologica, 88,(05), pp.: 522-528, 2003;http://www.haematologica.org ].Note: as chemotherapy is notoriously ineffective for most tumours, we wonder why it seems to beso effective in Hodgkin’s Lymphoma. You should keep in mind that many drugs can erroneouslygive haematological values similar to Acute Lymphocytic Leukaemia, Hodgkin’s Lymphoma orNon-Hodgkin’s Lymphoma. The patient’s immune response to germs or viruses (e.g.Mononucleosis) can also erroneously lead to a diagnosis of tumour.It extremely important to remember that Reed-Sternberg cells are typical not only of Hodgkin’sLymphoma, but also of Epstein Barr virus infectious mononucleosis ( 1292 )[ J.Kurtin: InterfollicolarHodgkin’s disease, Society for Hematopathology, Hematopathology Specialty Conference, 1996, Discussion, - Case #5, Mayo Clinic, Rochester, Minnesota,USA http://researchpath.hitchcock.org/socforheme/specialty/Spechem965.html ]The latter study was published ten years ago and stated that Reed-Sternberg cells are different fromHodgkin’s Lymphoma’s cells. Under the microscope, with immunoperoxidase staining inparaffinated sections, Reed-Sternberg cells that are present in interfollicular Hodgkin’s Lymphomaare phenotypically identical to Hodgkin’s cells in lymphomas at the stage of nodular sclerosis,mixed cellularity or lymphocytic depression. Indeed, they are all positive both to anti-CD 15antibodies (Leu-M1), anti-CD30 antibodies (Ber-H2), anti-CD45 antibodies (leucocyte commonantigen), and to anti-KiB3 antibodies ( 1293 )[Wilson CS: Malignant lymphomas that mimic benign lymphoidlesion: a review of four lymphomas, Semin. Diag. Pathos. 1995, 12(1), pp: 77-86]; ( 1294 ) [Fellbaum C.: Monoclonalantibodies k1B3 and Leu-M1 discriminate giant cells of infectious mononucleosis and of Hodgkin’s disease, HumPathos. 1988, 19, pp: 1168-1173].Reed-Sternberg cells are highly reactive lymphocytes which elaborate a variety of cytokines and320

growth factors. According to this article, it is likely that follicular hyperplasia is induced by Reed-Sternberg as a reaction to Hodgkin’s Lymphoma. According to Doggett ( 1295 ) [Doggett R.: InterfollicularHodgkin’s disease, Am. J. Surg. Pathos. 1983, 7, pp.: 145-149 1999http://www.mednat.org/cancro/Allegato%2022_DOGGETT.PDF ], Interfollicular Hodgkin’s disease stagemust be seen as the result of partial involution of the ill nodule, and not as a distinctive sub-type ofthe disease. In biopsies carried out on patients, one can see different stages of lymph nodes (nodularsclerosis, mixed cellularity, interfollicular areas). Therefore, the types of Hodgkin’s Lymphomawith follicular hyperplasia must be differentiated from other diseases, such as para-corticalimmunoblastic reactions:1.a) immunity reactions against various viruses, including Epstein Barr virus ( 1296 ) [Child CC: InfectiousMononucleosis. The spectrum of morphologic changes simulatine lymphoma in lymph nodes and tonsils.Am.J.Surg.Pathol. 1987; 11(2), pp.: 122-132 ; http://www.mednat.org/cancro/Allegato%2023_CHILDS.PDF];1.b) post-vaccination lymphadenitis ( 1297 ) [Hartsock RJ.: Postvaccinial lymphadenitis: Hyperplasia of lymphoidtissue that simulates malignant lymphomas, Cancer 1968, 21, pp.: 632-649];1.c) lymphadenopathies of autoimmune disorders such as adult Still's disease ( 1298 ) [Valente RM:Characterization of lymph node histology in adult onset Still’s disease. J.Rheumatol. 1989, 16, pp.: 349-354];1.d) Systemic Lupus Erythematosus (SLE)1.e) lymphadenopathy associated to drug hypersensitivity ( 1299 ) [Abbondanzo SL: Dilantin-associatedlymphadenopathy. Spectrum of histopatholologic features, Am. J. Surg. Pathol. 1995, 19(6), pp.: 675-686]; ( 1300 )[Saltstein SL: Lymphadenopathy induced by anticonvulsant drugs and mimicking clinically and pathologicallymalignant lymphomas, Cancer 1959, 12, pp: 164-182].All these disorders can be associated to para-cortical and follicular hyperplasia.All these conditions in a benign disease must be separated from Interfollicular Hodgkin’slymphoma.However, in infectious mononucleosis, a subset of immunoblasts can have cytologicalcharacteristics that are virtually identical to those of Reed-Sternberg cells.The diagnosis of Hodgkin’s Lymphoma is supported by a positive immunoreactive test made withanti CD-15 antibodies and a negative immunoreactive test made with anti-CD 45 antibodies.In Hodgkin’s Lymphoma with Reed-Sternberg cells, immunoreactivity to anti-CD 15 antibodies isabout 15-20%. However, all previously investigated benign immunoblastic reactions are negative toanti-CD15 tests, and positive to anti-CD 45 tests. According to Reynolds (1301), Epstein Barr virusreactive atypical immunoblasts are however phenotypically similar to Hodgking’s Lymphoma cells.Reynolds observed that it is possible to differentiate infectious mononucleosis from Hodgkin’sLymphoma thanks to the following three features:1.a) Immunoreactivity to CD15 (if Hodgkin’s Lymphoma).1.b) Absence of immunoreactivity to CD15 for Epstein Barr virus reactive immunoblasts.2.a) Presence of small collarette-shaped T cells around Hodgkin’s cells.2.b) Absence of small collarette-shaped T cells in Epstein Barr virus infectious mononucleosis.3.a) presence of Epstein Barr proteins in viral infections. ( 1301 )[Reynolds DJ: New characterization ofinfectious mononucleosis and a phenotypic comparison with Hodgkin’s disease, Am J. Pathos. 1995, 146(2), pp.: 379-388 ; http://www.mednat.org/cancro/Allegato%2024_RAYNOLDS.PDF]321

The immunophenotype of Reed-Sternberg cells is very variable. Thus, the presence of these cellsshouldn’t be immediately interpreted as a diagnosis of Hodgkin’s or non-Hodgkin’s Lymphoma, asthe use of CD-3, DAKO-M1 (CD15), L26 (CD 20), BerH2 (CD 30), MT1 (CD 43), DAKO-LCA(CD45RB), UCHL1 (CD45R0), LN2 (CD74) and DAKO-EMA antibodies in patients has beenproven not to be fully reliable ( 1302 ) [Wei-Sing Chu: Inconsistency of the immunophenotype of Reed-Sternbergcells in simultaneous and consecutive specimens from the same patients, American Journal of Pathology, vol. 141,No.1, 1992, pp: 11-17]. http://www.mednat.org/cancro/Allegato%2025_CHUENGLISH.PDFAnother work showing that it is difficult to diagnose Reed Sternberg cells in Hodgkin’s Lymphomavs infectious mononucleosis, is the work of Bitsori (1303) [Bitsori M.: Reed-Sternberg cells inatypical primari EBV infection, Acta Pediatrica, Vol. 90, No.2, 2001, pp: 227-229,3]. In particular,the distribution of Leu MI (CD15) antibodies themselves is not reliable ( 1304 ) [Sewell HF: Reaction ofmonoclonal antiLeu M1 - a myelomonocytic marker (CD15) –with normal and neoplastic epithelia 1987, Journal ofpathology, Vol. 151, No.4, pp.: 279-284; http://www.mednat.org/cancro/Allegato%2026_SEWELL.PDF]Finally, we report the question of differential diagnosis of sarcoidosis and lymphomas themselves,as the former is very often a consequence of chemotherapy ( 1305 ) [Dickerman Hollister: Sarcoidosismimicking progressive Lymphoma, Journal of Clinical Oncology, 2005, pp.: 8113-8116].Non-Hodgkin’s LymphomaIn a recent work of 2005, 374 patients who underwent chemotherapy were taken into consideration.Based on the International Prognostic Index (IPI), patients were divided into 4 groups: low risk,low-intermediate risk, high-intermediate risk, and finally high risk. The various survival curves thatwere obtained are not so different from the ones we already knew from medical literature:1) median survival (50%) of about one year for high risk patients, with a percentage of about 10%of survivors after the fifth year, and the curve going down in the following years;2) median survival (50%) of about 3 years for high-intermediate risk patients, with a percentage ofsurvivors of about 25% after the sixth year;3) median survival (50%) of about 4 years for low-intermediate risk patients, with a percentage ofsurvivors of about 40% after he sixth year and about 37% after the seventh year;4) median survival (50%) of about 8 years for low risk patients, with a percentage of survivorsslightly lower in the following years.( 1185 ) [M.van Agthoven: Cost determinants in aggressive non-Hodgkin’slymphoma, Haematologica, 90(5), pp.: 661-672, 2005].Note: as chemotherapy is notoriously ineffective for most tumours, we wonder why it seems to beso effective in Non-Hodgkin’s Lymphoma. You should keep in mind that some drugs canerroneously give haematological values similar to Acute Lymphocytic Leukaemia, Hodgkin’sLymphoma or Non-Hodgkin’s Lymphoma. The patient’s immunitary response to germs or viruses(e.g. Mononucleosis) can also erroneously lead to a diagnosis of tumour. For example we quote arecent Italian medicine book ( 1307 ), Savagno L.: “I linfomi Non Hodgkin”, Piccin Editore, pp.: 202:“… translocation is necessary but not sufficient for the neoplastic transformation of B lymphocytes.The reader should agree that monoclonality is usually a signal of malignancy, however this is notan absolute rule and there are exceptions. We have already seen that, at the beginning of an intenseand specific immune (defensive) reaction, lymphocytes proliferate indicating a uniform activation,and only a constraint that physiologically intervenes later makes reactive proliferation self-limiting.An enlightening clinical example is the case of F.R., a 28-year-old young man that underwent322

iopsy in 1994 because of a necrotizing tonsillitis with satellite adenopathy. The diagnosis of 3different pathologists suggested a malignant lymphoma with small classification differences amongthe three doctors. One of them had also detected that tonsillar lymphocytes were monoclonal. Whenthe medical oncologist visited F.R., before any antiblastic or radiant treatment, he still had a lymphnode measuring 2 cm in diameter in the gonion, while the tonsillar lesion had spontaneously healedduring treatment with sulphamidic drugs. A lymph node cytoaspiration showed a homogeneouslayer of atypical lymphoblasts that were often in mitosis and that looked malignant. Two days later,when F.R. had to be given the test results, his lymph node had reduced to a maximum diameter of5mm. A new cytoaspiration was carried out; this showed that there were no more proliferatingatypical lymphoblasts. A completely different cell population had substituted them: they werealmost exclusively mature plasmacells. Lymphocytes had typically evoluted into blasts, that in theirturn changed into plasmacells. This allowed to understand the whole episode correctly: it wasn’t aneoplastic disease, but a phlogistic-reactive disease. No antitumoral treatment was therefore given.The young man is now going towards the mature age without lymphoma, ten years after thisepisode. The lesson here is that monoclonality is almost a constant feature in neoplasias, but initself it is not enough for an absolutely certain diagnosis…[ ( 1307 ), Savagno L.: I linfomi NonHodgkin, Piccin Editore, pp.: 202: http://www.mednat.org/cancro/Allegato%2027_SALVAGNO.PDF ]ConclusionPaul Winter shows a harsher version of facts and explains the dynamics of the system in this way:“It is unlikely that a doctor consciously stops an oncologic therapy to protect his business or hiscareer. But every doctor has his own ideas about what is the best treatment, based on what helearned. However, chemo pharmaceutical multinationals have a very strong influence on what istaught to doctors. Doctors are too busy to study more statistics about cancer treatments, and takefor granted that what they are taught at university, or what is shown in medical journals, is the bestpossible treatment, as it is scientifically proven. Nor can they suspect that such treatments are thebest thing only for chemo pharmaceutical multinationals, which exert their influence on “high-levelmedical cultural institutions” belonging to them… (Winter, Paul: the Cancell Home page,http://www.best.com/handpen/Cancell/cancell.htm ).On 9 January 1991, dr. Martin F. Shapiro wrote on the Los Angeles Times, supporting the ideaaccording to which chemotherapy is NOT curative and that it really has very little effect on themost common types of cancer: “While some oncologists inform their patients on the lack ofevidence that this therapy really works, other doctors could have been mislead by scientificdocuments that are optimistic about chemotherapy without guarantees. Other doctors are stillsensitive to economic benefits. Doctors can earn much more money with chemotherapy than givingcomfort to dying patients and their families…”.Dr. Samuel Epstein stated on 4 February 1992: “We are worried that the system that was foundedagainst cancer, the National Cancer Institute (NCI), the American Cancer Society (ACS) and abouttwenty more centres for cancer treatment have mislead and confused the public opinion and theCongress (of the United States) through repeated statements according to which we are about towin the war against cancer…”.As far as chemotherapy is concerned, the author of this work claims the right to complete freedomof therapy and technical autonomy (art. 12, Italian Medical Deontology Code), because of hiscontrary clinical beliefs, founded on countless scientific trials. He responsibly chooses to applymore suitable diagnostic and therapeutic remedies, practising what is often stated in legal literature,especially in Amedeo Santosuosso’s work (“Libertà di cura e libertà di terapia. La medicina tra323

azionalità scientifica e soggettività del malato”, Il Pensiero Scientifico Editore, 1998, page 57),where he states, as a comment to article 19 of the Medical Deontology Code:“…Freedom of evaluation by the doctor is controlled by article 19, called “Refusal of professionalperformance”. According to this article, that substantially reproduces the text of the previousDeontology Code, the doctor can refuse to perform his job, if he is asked to do something againsthis conscience or his clinical beliefs, unless his behaviour is immediately and seriously harmful forthe patient…”It should be noticed that this rule is particularly broad and strict. Indeed, it allows objection ofconscience not only when the law allows it and according to those procedures, but in all cases.Moreover, it allows to refuse therapies because of mere clinical beliefs, even when no consciencequestions are involved. The only limit is about extreme situations, when the patient could beseriously and immediately harmed.Besides, the Court of Cassation is very clearly in favour of the doctor’s autonomy in therapeuticchoices. This is a sentence of 2001 (Section IV, sent. n. 301/2001):“…It is fair to emphasize the doctor’s autonomy in therapeutic choices, because, as medicine hasno own scientific protocols based on mathematics, it often implies different practices or solutionsthat were shown to be effective thanks to experience. These solutions have to be chosen with acareful evaluation of a series of variants that only a doctor can evaluate. This freedom oftherapeutic choices cannot be ill-considered nor based only on personal experience. Once thechoice is made, the doctor must continue to carefully observe the situation, in order to interveneimmediately in case an emergency arises, if he understands that his choice was not appropriate.When all this is realized, the doctor cannot be responsible of a possible failure. To evaluate if thetherapeutic choice was right and if he acted out of inexperience, the judge must give an “ex-ante”judgement, that is, he must go back to the moment when the doctor has to choose, and consider thescientific bases of his choice…”.324

QUESTIONS to ask your DOCTORThey are formulated on the basis of a book published by an Australiandoctor in 2004: Morgan G.: The contribution of cytotoxic chemotherapy to5-year survival in adult malignancies, Clinical Oncol., 2004, 16, pages.:549-560 (the attachment is available in PDF format onwww.mednat.org/cancro/MORGAN.PDF).Is it true that out of more than 3,500 American patients undergoingChemotherapy for Cancer of the Pancreas, none of them was still aliveafter 5 years?Is it true that out of more than 850 American patients undergoingChemotherapy for Sarcoma, none of them was still alive after 5 years?Is it true that out of more than 8,500 American patients undergoingChemotherapy for Melanoma, none of them was still alive after 5 years?Is it true that out of more than 4,500 American patients undergoingChemotherapy for Cancer of the Uterus, none of them was still alive after5 years?Is it true that out of more than 23,000 American patients undergoingChemotherapy for Cancer of the Prostate, none of them was still aliveafter 5 years?Is it true that out of more than 3,000 American patients undergoingChemotherapy for Kidney Cancer, none of them was still alive after 5years?Is it true that out of more than 1,700 American patients undergoingChemotherapy for Multiple Myeloma, none of them was still alive after 5years?Is it true that out of more than 3,000 American patients undergoingChemotherapy for Cancer of the Stomach, only 0,7% were still alive after5 years?Is it true that out of more than 14,000 American patients undergoingChemotherapy for Colon Cancer, only 1% were still alive after 5 years?325

Is it true that out of more than 30,000 American patients undergoingChemotherapy for Breast Cancer, only 1,4% were still alive after 5 years?Is it true that out of more than 5,000 American patients undergoingChemotherapy for Head and Neck Cancers, only 2% were still alive after5 years?Is it true that out of more than 5,000 American patients undergoingChemotherapy for Rectal Cancer, only 3% were still alive after 5 years?Is it true that out of more than 1,800 American patients undergoingChemotherapy for Brain tumours, only 3,7% were still alive after 5years?Is it true that out of more than 1,500 American patients undergoingChemotherapy for Oesophageal Cancer, only 5% were still alive after 5years?Is it true that out of more than 20,000 American patients undergoingChemotherapy for Cancer of Lung, only 2% were still alive after 5 years?Is it true that out of more than 3,000 American patients undergoingChemotherapy for Ovarian Cancer, only 9% were still alive after 5 years?Is it true that out of more than 6,200 American patients undergoingChemotherapy for NON-Hodgkin’s lymphoma, only 10% were still aliveafter 5 years?Is it true that out of more than 1,800 American patients undergoingChemotherapy for Uterine Cervix, only 12% were still alive after 5 years?Is it true that out of more than 800 American patients undergoingChemotherapy for Hodgkin’s lymphoma, only 40% were still alive after 5years?Is it true that out of more than 900 American patients undergoingChemotherapy for Testicules tumors, only 40% were still alive after 5years?326

Chapter 18:Dangerous PlantsChap. 18.1.:Plants that are potentially efficient against tumors, but whose heavyside-effects are already known or suspected in their use1) Dry root of Asclepias tuberose (Pleuresy-root): contains glycoside asclepiad, asclepion;its potential apoptotic property is being evaluated, as long as it is active only on tumourcells, with the exclusion of side affects similar to Chemo-Therapy (CH.T.) In the past itwas employed to cure plueuresy. Similar to Bryonia cretica (Cretan Bryony).2) Baptisia tinctoria (Wild indigo): seems to act as a stimulant of the immune system; itspotential apoptotic property is being evaluated, if active only on tumoral cells, withexclusion of side affects similar to Chemo-Therapy.3) Fresh root of Bryonia cretica, (Cretan Bryony) gathered before it blooms: containsseveral bitter Cucurbitacin compounds, Bryoside, Triterpin bryonol, (crysofanic acid)polysaccharides; its potential apoptic property is being evaluated, as long as selectiveonly on tumour cells, with the exclusion of side-effects like those caused by Chemo-Therapy. Similar to Aesclepia tuberose.4) Consolida regalis [Ranuncolaceae] (Royal Knight’s spur): Toxic plant the use of whichis now allowed only under medical supervision. In the past Castore Durante mentioned itwas effective against “tumours”. The author of the present work is evaluating itspotential apoptic effect, as long as this is selective only on tumour cells and does notproduce any side-effects similar to Chemo-Therapy.5) Clematis recta (Ground virginsbower) stem with flower and leaves: contains Anemonin,anemone Camphor; the leaves and stalk are toxic; it acts on the lymph glands, themammary glands, testicles, prostate gland, urethra; its potential apoptic properties arebeing analysed as long as only tumour cells are involved, excluding side effects similarto Chemo-Therapy.6) Dry seeds of Croton tiglium (Purging Croton): Forbole fatty acid di-ester, toxic crotin,protein, glycoside crotonoside; its potential apoptic effect is being evaluated, as long asselective only on tumour cells, excluding side-effects similar to Chemo-Therapy.7) The dark red milky substance of Croton draconoides; perhaps the same as Crotontiglium (Purging Croton), its potential apoptic properties are being analysed as long asonly tumour cells are involved, excluding side effects similar to Chemo-Therapy.8) Daphne mezereum (Daphne, Spurge Laurel): fresh bark of branches, picked beforeblooming; contains Daphnine, Umbelliferone, malic acid, mezerean resin; it has asuspected immune-stimulating effect; heals Herpes Zoster; its potential apoptic effect is327

eing evaluated, as long as selective only on tumour cells, excluding side-effects similarto Chemo-Therapy.9) The milky substance of Euphorbia resinifera (Resin Sandmat): contains Euphorbon,euphorgenic acid; its potential apoptic effect is under evaluation, as long as selectiveonly on tumour cells, excluding side-effects similar to Chemo-Therapy.10) Euphrasia officinalis extract (Common Eyebright): contains Rhinantin, Acubin; itspotential apoptic effect is under evaluation, as long as selective only on tumour cells,excluding side-effects similar to Chemo-Therapy.11) Dried root of Helleborus niger (Black Hellebore): it contains hellebrin, helleborin andglucosides similar to Digitalis; it has been employed empirically in non-dynamicconditions of cachesia connected to cancer; it is active also at cardiac-circulatory level;its emuntory function on kidneys, has been proven; its potential apoptic effect is underevaluation, as long as selective only on tumour cells, excluding side-effects similar toChemo-Therapy.12) Hyoscyamus niger (Henbane): contains Scopolamine, Atropin; used in the past forrespiratory and bladder ailments; its potential apoptic effect is under evaluation, as longas selective only on tumour cells, excluding side-effects similar to Chemo-Therapy.13) Kreosotum species (Beech wood): contains Guajacol and Creosol; used empirically inthe past in the treatment of carcinoma; suspected immune-stimulating action; itspotential apoptic effect is under evaluation, as long as selective only on tumour cells,excluding side-effects similar to Chemo-Therapy.14) Lophophutum leandri: it contains leuco-cyanide components, tanning (hide industry)substances, catechines, bitter substances, traces of Iodine and Bromide; employedempirically ailments connected to liver, tyroid gland (strumi), angina pectoris; itspotential apoptic effect is under evaluation, as long as selective only on tumour cells,excluding side-effects similar to Chemo-Therapy.15) Juniperus sabina: contains Sabinol, Cadinene, Pinene; employed empirically in thetreatment of condiloma; its potential apoptic effect is under evaluation, as long asselective only on tumour cells, excluding side-effects similar to Chemo-Therapy.328

Chap. 18.2.: Plants to Absolutely avoid using1) Aethusa cynapium [Umbelliferae] (Fool’s Parsley) (potentially toxic);2) Aconitum nepellus (True Monkshood): toxic plant, already known: its roots (toxic, like therest of the plant), are very similar to those of the Turnip;3) Alpinia officinarum (Galanga) (Colic root): contains Amphetamine ( 621 );4) Anagallis arvensis [Primulaceae] (Scarlet Pimpernel): Anagallide (potentially toxic);5) Arum maculatum [Araceae] Cuckoo Pint, Aro, Gighero, Gigaro (Toxic);6) Bryonia dioica [Cucurbitaceae]: Cretan Bryony, (potentially toxic);7) Camptotheca acuminate: camptothecin is extracted from this plant, a substance thatproduces inhibition of the topoisomerases I with severe immune-depleting co-lateral effectsof its action on tumour cells;8) Cannabis sativa indica (Maryuana): well known drug and as such causes, in time, seriousirreparable damage to the brain;9) Centaurea solstizialis [Compositae asteraceae]: the main active principle uses the receptorsfor tubulin as colchicin, impeding polymerization through metaphasic shield (Hokanson,Diss. Abstr. Int.B, 37, pp. 1265, 1976); it therefore affects both ill and healthy cells,impeding the polymerization of DNA through a metaphase shield;10) Chelidonium majus (Celandine): contains Chelidonin, Chelidoxantin, Fumarin; causes seriousdamage to DNA cells, including the healthy ones. A semi- synthetic substance ofChelidonin alkaloid has been obtained from this plant. Ukrain has also been derived from thisplant, with the addition of 3 atoms of phosphorus. It is still however toxic;11) Cicuta virosa [Umbelliferae] (Mackenzie’s water hemlock): Very toxic;12) Cinoglossum officinale [Boraginaceae] (Hounds tongue): contains pyrrolizidine alkaloids,useful in gastroenterology therapy and in treating sores. Note: Toxic to the liver. It seems tohave, however, an anti-neoplasm effect although the basis of which is unknown;13) Claviceps purpurea or Secale cornutum (Ergot): highly toxic;14) Clematis vitalba (Evergreen clematis): venomous plant;15) Colchinum autumnale [Liliaceae] (Autumn crocus): active on both healthy and ill cells,impeding the polymerization of DNA through a metaphase shield, the active principlesof this plant are at present employed in Chemo-Therapy;16) Colchicum luteum [Liliaceae]: Meadow saffron (very toxic);17) Colubrina texensis [Ramnaceae]: Texan hogplum: its active principle, Maytansin, blockthe cells in metaphase, the same way it does with Vinca rosea (Rosy periwinkle);329

18) Conium maculatum [Umbelliferae]: Poison hemlock (very toxic);19) Croton tiglium: active on both healthy and ill cells, impeding the polymerization of DNAthrough a metaphase shield (toxic);20) Croton draconoides : active on both healthy and ill cells, impeding the polymerization ofDNA through a metaphase shield (toxic);21) Daphne laureola [Timeleaceae]: Spurgelaurel (very toxic);22) Daphne mezereum [Timeleaceae]: Paradise plant (toxic);23) Digitalis purpurea [Scrofulariaceae]: Purple foxglove (very toxic);24) Dieffenbachia picta [Araceae]: Dumb cane (toxic);25) Euphorbia marginata [Euphorbiaceae]: Spurge (toxic);26) Euphorbia pulcherrima [Euphorbiaceae]: Poinsettia (toxic);27) Ferula communis(or narthex scorodosma foetida) [Umbelliferae]: Giant fennel (toxic);28) Ferula Juniperus or Sabina [Cupressaceae]: (potentially toxic);29) Linum album [Linaceae]: American Mandrake. Contains podophyllotoxin (SEEPodophyllum peltatum). It is believed that the mechanism of action can be compared tothe one found in colchicines. It therefore acts both on the ill cells and on the healthyones, impeding the polymerization of DNA through mitotic block. The active principlesof this plant are at present employed in Chemo-Therapy;30) Lonchocarpus nicou [Leguminosae]: Barbasco. Rotenone is extracted from this plant,competing with colchicines for the binding site on tubulin having the same actionmechanism; therefore, its action is both on the ill and healthy cells, impedingpolymerization of DNA with mitotic block. Active principles of this plant are at presentemployed in Chemo-Therapy;31) Mandragora officinarum: Mandrake. Employed in Chemo-Therapy; the well-knownchemotherapy drugs Etoposide (VP-16) and Teniposide are extracted fromPodophyllotoxin;32) Oenanthe aquatica [Umbelliferae]: Fineleaf waterdropwort (very toxic);33) Oenanthe crocata [Umbelliferae]: Waterdropwort (very toxic);34) Oenanthe phellandrium [Umbelliferae]: Water fennel (very toxic);35) Paris quadrifolia [Liliaceae]: Herb-paris (potentially toxic);36) Podophyllum peltatum [Berberidaceae]: Mayapple. The presence of resin characterizedby lacton isomers of podophillic acid, identified as Podophyllotoxin which together with330

other molecules, makes up the entire complex of Podophyllin. A number of well-knownchemotherapy drugs like teniposide and etoposide are obtained from the latter. It isbelieved that its mechanism of action is similar to colchicines. It is therefore active onboth ill and healthy cells, impeding polymerization of DNA with mitotic block. Theactive principles of this plant is at present employed in Chemo-Therapy.37) Prunus laurocerasus [Rosaceae]: Cherry laurel (toxic);38) Rhus cotinus [Anacardiaceae]: Poison oak (toxic);39) Rhus toxicodendron : Red Smoke Tree (highly toxic);40) Ruta graveolens [Rutaceae]: Common rue (potentially toxic);41) Salvia divinorum: Diviner’s sage. Toxic; characterized by long-term severe braindamage with no hope of recover.42) Sangiunaria canadensis: Bloodroot. Contains several alkaloids, in particularSanguinarin, chelidonic acid, cheleritrin. Its mechanism of action is similar tocolchicines; it therefore acts on both the ill and healthy cells impeding polimerization ofDNA with mitotic block;43) Senecio aureus or vulgaris [Compositae] (Old-man-in-the-Spring-Ragwort). Its action issimilar to that of alkaloids in Spurred rye and it, too contains pyrrolizidinic alkaloids(mutagens and hepatoxic cancer agents);44) Solanum dulcamara [Solanaceae]. Climbing nightshade contains an alkaloid, glycosidetomatidenol. In the past the green leaves and fruits of this plant were used for breastcarcinoma ( 736 ). It is at present considered a poisonous plant;45) Spartium juniceum [Papilionaceae]: Spanish broom (toxic);46) Steganotaenia araviacea: an African plant containing Steganacin when hydrolysing theguanosintriphosphate, blocks the polymerization of tubulin through receptor sites similarto colchicine. It is active therefore on both ill and healthy cells, impeding polymerizationof DNA through metastatic block;47) Strychnos ignatii (or Ignatia amara): Ignatious bean. Contains strychnine;48) Strychnos nux-vomica: Poison nut. Contains strychnine;49) Taxus baccatus [Taxaceae]: Yew, Tree of Death. Its action mechanism is similar to thatof colchicine;50) Veratrum album [Liliaceae]: Hellebore (toxic);51) Veratrum nigrum [Liliaceae]: Black False Hellebore (toxic);52) Vinca rosea [Apocyanaceae]: Periwinkle. The well-known Chemo-Therapy drugsVinblastine, Vincristine, Vinleurosin and Vinrosidine are derived from this plant.331

Chap. 18.3.: Families of dangerous or prohibited plants:All plants belonging to the Apocinaceae family.Nerium oleander [Apocinaceae]: Oleander (toxic);Vinca major: Bigleaf periwinkle (toxic);Vinca minor: Common periwinkle (toxic);Vinca rosea: Rosy periwinkle (toxic).All plants belonging to the Ranuncolaceae family (almost all of those mentioned in the presentparagraph):Aconitum napellus (Venus’ chariot), Actea (Red baneberry), Adonide, Anemone, Columbine, Calta,Hellebore, Hepatica, Favagello, Pasqueflower, Ranunculus, Larkspur, Evergreen clematis):Aquilegia vulgaris [Ranuncolaceae]: European columbine;Aconitum delphinifolium [Ranuncolaceae]: Monkshood (toxic);Aconitum ferox: Indian aconite (toxic);Aconitum heterophyllum [Ranuncolaceae]: Atis (toxic);Aconitum napellus [Ranuncolaceae]: Venus’ chariot (very toxic);Actea spicata [Ranuncolaceae]: Red baneberry (toxic);Adonis spinosa [Ranuncolaceae]: Pheasant’s eye (toxic);Anemone epatica [Ranuncolaceae]: Anemone (potentially toxic);Anemone nemorosa [Ranuncolaceae]: European thimbleweed (potentially toxic);Anemone pulsatilla (or Pulsatilla nigricas): European pasqueflower (toxic);Consolida regalis [Ranuncolaceae]: LarkspurHelleborus niger [Ranuncolaceae]: Black hellebore (toxic);Ononis spinosa [Ranuncolaceae]: Spiny restharrow (toxic);Ranunculus acris [Ranuncolaceae]: Tall buttercup (potentially toxic).Almost all the plants belonging to the Solanaceae family, with the exclusion of Solanumlycopersicum (Tomato), Solanum melongena (Eggplant), Solanum tuberosus (Potato), listed in thepresent paragraph are toxic. (Note: a number of Solanaceae are still under evaluation):Atropa acuminate [Solanaceae]: Indian nightshade (very toxic);Atropa belladonna [Solanaceae]: Nightshade (very toxic);Datura stramonium [Solanaceae]: Jimson weed (very toxic);Hyoscyamus niger [Solanaceae]: Black henbane (very toxic);Lycium chinense [Solanaceae]: Chinese Wolfberry (toxic);Lycium europaeum [Solanaceae]: European Wolfberry (toxic);Mandragora officinarum [Solanaceae]: Mandrake (potentially toxic);Nicotiana alata [Solanaceae]: Nicotina or Tabacco (potentially toxic);Nicotiana tabacum [Solanaceae]: Tabacco (potentially toxic);Solanum dulcamara [Solanaceae]: Woody nightshade (potentially toxic);Solanum nigrum [Solanaceae]: Black nightshade (potentially toxic);Solan:um quitoense [Solanaceae]: Lulo (under evaluation);Solanum photeinocarpum [Solanaceae]: Black nightshade;Solanum surattense, xanthocarpum [Solanaceae]: Kantikari (under evaluation).332

Chapter 19:The Law of the Rommunes (*)In this Book, FOUR QUESTIONS are indicated:A) The Chemo-therapy is a failureAny form of Chemo-Therapy causes irreparable damage to the physical condition of whoeverexposes themselves to the action of these poisons called "cyto-toxic medicines". The Hippocraticoath declares that it is forbidden to administer "poison" to a patient, even if that patient himself asksfor it (SEE the Hippocratic Oath). General failure of Chemo-Therapy against nearly all forms oftumor: Chemo-Therapy reduces the tumoral mass, but at the great expense of causing severedamage to all the patient’s organs and tissues (see: chap 17.2: the failure of the Chemo-Therapy ).B) Very chemo-pharmaceutical multinational Policy (BIG-PHARMA)concerning public health in Europe (SEE chap. 1.2: “Herb-Therapy must not beprohibited”)The European Commission has proposed a directive on vitamin integrators, natural and nutritionalproducts in the European Union. This Project of the European Commission aims to favor those whoare making a profit from the main illnesses of deficiency which are now widely spread across thewestern countries (cancer, cardio-vascular diseases, diabetes, “american” obesity, hyper-tension,Alzheimer's, Parkinson’s disease, Acquired Immuno-Deficiency Syndromes, etc…) that is to saythose companies which make their profits from illnesses, instead of health: in other words, themajor chemical and pharmaceutical industries. It can therefore be maintained that thePharmaceutical Multinationals act through international institutions such as the EuropeanCommission and the Codex Alimentarius (a branch of the United Nations Food and AgriculturalOrganization), to pursue their more or less illicit money-making activities: for example, they haveestablished the RDAs ( Recommended Daily Allowances ), also known as PRI’s ( PopulationReference Intakes ), an acronym which indicates the quantities of vitamins and minerals, that is, thequantities of nutriments that are absolutely scurvy and beriberi. But the recommended quantities arenot sufficient, nor have they ever been thought of for the prevention of the deficiency diseasesmentioned above (cancer, cardio-vascular diseases, diabetes, “american” obesity, hyper-tension,Alzheimer's, Parkinson’s disease, Acquired Immuno-Deficiency Syndromes, etc…), that is, toguarantee good health by enforcing the organism’s defenses. Nevertheless, the EuropeanCommission’s proposal for a directive on vitamin integrators contemplates “maximum levels ofdosage to be determined according to an analysis of risks, carried out with scientific methods,taking into account the contribution of vitamins and minerals from other nutriments…”, and alsothe “Population Reference Intake”. The answer could be the following: the directive proposed bythe European Commission has been formulated on the suggestions of the Pharmaceutical Cartel,and it is the last attempt to eliminate the growing competition of biological substances provided bynatural and nutritious products including alimentary integrators, consisting of over 13.000 essentialvitamin principles.(*) This Documents on “the Low of the Rommunes” has been written in “Old Imperial English”333

C) Demonstration of the immediate perils brought about by the introduction ofGenetically Modified Organisms (GMO) in Europe, including the consequent failureof natural anti-cancer therapies. (SEE chap. 2.22: “The Threat of GeneticallyModified Organisms”).Therefore transgenic products represent, precisely by the way they are conceived, a formidableattempt to accentuate the unilateral characteristics of single crops, and thus the disappearance of thenatural genetic patrimony which has existed for hundreds of millions of years. We will no longerhave, in the near or not so near future, all those varieties of plants (for food or not) which arecharacteristic to every national or local region. The environmental, genetic contamination inducedby hybrid creations of the large seed industries of GMOs, which will inevitably crossbreed withthose varieties present in nature, will bring about a loss of the natural genetic patrimony (in no wayrecoverable), of all those particular characteristics which have become part of the genome of plantsduring the course of the long processes of adaptation to the various environmental situations. Todaysuch a loss is really serious even for the natural environments such as forests. Substantiallyspeaking, the very basis of human biochemistry is threatened today in its most intimate essence(human DNA) by the inconsiderate use of these artificial plants, with no possibility of recoveringthe genetic patrimony of more than 440,000 species of plants classified (out of an estimated total of600,000 – 800,000), of which a substantial part will disappear over the course of a few hundredyears, destroyed at their very base by genetic damage introduced by man. The plants are complexorganisms, they are the fruit of hundreds of millions of years of biological evolution: every geneticmodification caused in plants by man (with radiation such as Chernobyl, or with viruses such aspresently used in GMO), however small that modification is, will cause damage, irreparable damagewhich often cannot be seen, because man only knows a limited number of safe vitamins and provitaminsubstances. However, there are tens of thousands of vitamins and other substances presentin plants, and it is these which are responsible for the correct working of the biochemical humancomplex and the human genome (DNA).D) Alliance policy between chemo-pharmaceutical multinational Companies(BIG-PHARM) and the new Food and Agriculture Multinational Industries(GMO): SEE chap.6.b: “The corrupt alliance between the Food and AgricultureMultinational Industries (GMO) and the chemo-pharmaceutical Companies (BIG-PHARMA)1) Agro-industrial Multinationals (OGM)For some years we have been witnessing the birth of multinationals which define themselves as “science of lifemultinationals”, which are active in the pharmaceutical market, agri-business (seeds and pesticides) and the veterinarybusiness. They are, in themselves, different sectors, but they are linked by the use of biotechnology (GMO) to producetheir products. These multinationals are using unscrupulous and aggressive economic strategies: since the beginning ofthe 90s they have been working towards buying companies, even large companies.One of these, Monsanto, within the space of a few years has acquired Asgrov, Agracetus, De Calb, and Cargil investing10 billion Euros.Another big group, Dupont, has acquired Pioneer, investing about 8 billion Euros.These investments do not seem to have any economic logic: they pay much more for the companies than their actualvalue, as if they were trying to eliminate a potential competitor rather than obtain a short term economic result.Alongside the acquisitions we also have the mergers: Ciba Geigy and Sandoz created Novartis (with a turnover of 20billion Euros in the year 1997-98).From the merger of the French company Rhone Poulenc and the German company Hoechst we have the new companyAventis.334

Still within this context, Syngenta, the first worldwide agrochemical group was founded in October 2000. It is the resultof a merger between the Swiss company Novartis (a company well-known for producing medicines for chemotherapy)and the Anglo-Swedish company Astra-Zeneca (a company also well-known for producing medicines forchemotherapy), and will have a turnover of about 8 billion euros. Monsanto, after its merger with Pharmacia & Upjohn,a large pharmaceutical industry (this too is well-known as a producer of medicines for chemotherapy) now concernsitself only with agriculture, with a turnover which in 2000 reached 5.5 billion dollars.The current situation stands thus: a few multinationals (Syngenta, Monsanto, Novartis, Dupont and Aventis) have 25-30% of the seed market (but more than 90% of the transgenic seed market) and behind these big groups there is aplethora of smaller companies which makes one think that this trend can only get stronger in the future, since mediumsize companies cannot compete with these big groups. The objective seems clear: to convert the traditional seed marketinto a biotechnical one (that is, GMO). But the worrying fact is that we find the same names in the field of pesticides,where the same companies control 55% of the market, and in the pharmaceutical field where the same companies play adominant role.2) Chemical-pharmaceutical Multinationals (Big-Farma)The history of the chemical-pharmaceutical multinationals is incredible because of their rapid development, and todaythey are connected to the agro-industrial sector in an extremely dangerous way.The chemical-pharmaceutical industry started in Europe in the second half of the nineteenth century: in many cases theywere dyeing industries which, moving away from basic chemistry, moved towards the new and more promising fieldsof specialized chemistry in key economic fields.Before the Second World War, a powerful international pharmaceutical cartel developed in Germany. It controlledglobal pharmaceutical companies and chemical plants and was active in 93 countries, representing a powerful economicand political force in each of them. It was known as I.G. Farben. It would become the main supporter of Hitler’schemical production during the years of war, offering products such as high explosives, toxic gases and the ignominiousZyklon-B, the lethal substance used by Nazis in the death camps. In 1928, however, before the outbreak of war, theAmerican monopolist manufacturer John D. Rockfeller had merged his international empire in America with I.G.Farben, creating the largest and most powerful pharmaceutical cartel ever seen.The Military Nuremberg Tribunal established in 1946/47 that the Second World War would not have taken placewithout this petrochemical cartel called I.G. Farben. As a consequence of the sentence passed by the Tribunal, I.G.Farben was divided into Bayern, BASF and Hoechst, and some executives were condemned for initiating a war againstinternational law, genocide, the exploitation and looting of private and public properties in foreign countries and othercrimes against humanity.The events leading to the war and linked to this powerful cartel are reported in Joseph Borkin’s The Crime andPunishment of IG Farben.After the war, Germany, with its three large companies Bayer, Hoechst and BASF (which encouraged the rise of Hitler’snational socialism), played an important role. So did Switzerland, which, in Basle, saw the founding and thedevelopment of companies Ciba, Sandoz and Roche – all of which later spread throughout the world.But it was in the 1990s that the really big mergers started: in 1989, in the United Kingdom two big pharmaceuticalcompanies merged to form Smith Kline – Beecham: later they merged with American Home (with an annual turnover ofabout 25 billion Euros).In 1993 the Swedish company Pharmacia bought the Italian company Farmitalia-Carlo Erba, then it merged with theAmerican company Upjohn in 1995, and then again with Monsanto, before being bought by Pfizer which hadpreviously bought the American company Parke Davis.In 1995 there was the Glaxo-Wellcome merger (with an annual turnover of about 14 billion Euros).In 1998 Smith-Kline-Beecham (with an annual turnover of 62 billion Euros) merged with Glaxo-Wellcome (with anannual turnover of about 90 billion Euros) to make an annual turnover of more than 150 billion Euros.In the meantime the English company Imperial Chemical Industries merged with the Swedish company Astra, formingthe company Astra-Zeneca.These mergers have continued among the same companies operating in the same field: Santoz and Ciba Geigy(Novartis, 1996), Astra-Zeneca (1998).Their turnovers are in the range of the GDP (Gross Domestic Product) of many western countries. These hugecompanies have not been founded for the good of the patient but out of the need to create monopolies and hence everbigger profits.Ultimi dati :335

giugno 2002 : acquisto della Aventis da parte della Bayer; l'accordo ha così permesso alla Bayer di fare il proprioingresso nel campo delle sementi OGM. La fusione ha portato alla creazione della Bayer CropScience che si componeora di tre gruppi commerciali principali: Crop Protection, Bio Science ed Environmental Science.giugno 2005: acquisto della Sementis da parte della Monsanto.ST. Louis, Jan. 24, 2005: Monsanto Company to acquire Seminis, Inc., a leading Vegetable and Fruit SeedCompany.ST. Louis (Jan. 24, 2005). Monsanto Company announced today that it signed a definitive agreement to acquireSeminis, Inc., for $ 1,4 billion in cash and assumed debt, plus a performance-based payment of up to $ 125 millionpayable by the end of fiscal year 2007.“The addition of Seminis will be an excellent fit for our company as global production of vegetables and fruits, and thetrend toward healthier diets, has been growing steadily over the past several years, “ said Hugh Grant, chairman,president and chief executive officer of Monsanto. “Seminis is uniquely positioned to capitalize on this fast-growingsegment of agriculture, and the acquisition likewise expands Monsanto’s ability to grow. We look forward to furtheringthe growth and leadership position established by Alfonso Romo and his team as the Seminis business is an importantextension to our agricultural seeds platform.”Seminis is the global leader in the vegetable and fruit seed industry and their brands are among the most recognized inthe vegetable-and-fruit segment of agriculture. Seminis supplies more than 3,500 seed varieties to commercial fruit andvegetable growers, dealers, distributors and wholesalers in more than 150 countries around the world.In addition to Seminis leading presence in the vegetable and fruit seed industry, which is expected to contribute toMonsanto’s financial results in the near-term, Monsanto management sees additional benefits longer term. From atechnology perspective, Monsanto intends to continue on the path taken by Seminis for its business which is to focus ondeveloping products via advanced breeding techniques. Longer term, biotechnology applications could be an option,and will be evaluated in the context of Monsanto’s research-and-development priorities and potential commercialbusiness opportunities.The perverse allianceOne can thus affirm that the two cardinal points of the economy and the life of the individual, agriculture andpharmaceuticals, are substantially under the control of a few multinational groups.It is on the basis of this that the author has written the Seventh and the Eight Declarations.But, I have a Dream…Will a Judge ever be so courageous as to give back to Jurisprudence its profound sense ofJustice?Will the courage ever be found to rediscover the original mode of administrationin a Democracy (Demou Kratos = Power of the People), the “Res Publica” (publicThing), which lies at the very foundation of Ancient Law ?The Ancient Law which was born over three thousand years ago in an ordinaryvillage of shepherds, set to guard an ordinary ford of an ordinary river, asluggish, chalky stream of water, ever dry in summer, an obligatory passage forflocks of sheep and goats…A small, ordinary village, where dwelled people proud and unbowed.People out of the ordinary who had conceived and affirmed the incredible, outof-the-ordinaryidea that “NO ONE WAS OBLIGED TO OBEY ANYONE, BUT336

THEIR STRICT LAWS: LAWS WHICH THEY THEMSELVES HAD IMPOSED ONTHEMSELVES, LAWS WHICH THEY THEMSELVES HAD CHOSEN ANDVOTED, STRICT LAWS, BEFORE WHICH THEY WERE ALL EQUAL: FROMTHE POOREST TO THE RICHEST.”The respect for their sacred Laws was so strong that they used them even in war,thus they were the original inventors of military discipline, and thus created—from nothing—an army of free men who would go on to write history in thefollowing one thousand and five hundred years.Their military strength lasted so long because the defence of their individualfreedom, of their ideal Laws, was worth more than their own lives and even ofthat of their little village of shepherds…This, I believe might be why they never lost a war.They disappeared from History only when they ceased to administer their sacredlaws with Justice, Honour and Respect towards the Citizen, and insteaddelegated their individual freedom to an Emperor…Nobody knows when the village which was to change the History of the Worldwas born.It is not even known what their original name was.There are scholars who say that it was the Greeks from the South of Italy whogave them the name of “Ronnùmes”, or “Rommùnes”, because no one succeededin making them submit.“Rommùnes” indeed comes from the Greek word “ROME” (Strength) and theword “Rommùnes” signifies “The Strongs”, “The Courageouses”, “They who arestrongly armed”…And it was the name “Rommùnes” that the other Italic tribes then also used todenominate them, since the name instilled fear and respect.They were free men, and their sense of Justice contrasted with the arrogance andthe barbarities of the neighbouring peoples, who did not have that out-of-theordinarysense of “ABSOLUTE AND TOTAL EQUALITY OF ALL BEFORE THELAW”.In the “square City of the Rommùnes”, even the poorest person had the right tosue the mightiest of the community, if the latter was accused of having violatedtheir sacred Laws.337

The citizens would then have judged, in a public assembly, in broad daylight,without complicity and subterfuge, the accused and the accuser, both placed onthe same level of justice, albeit from the very outset premising that the accusedwas Presumed Innocent, and verifying the truthfulness of the Evidence.Three thousand years ago…People out of the ordinary, the Rommùnes.It seems that the ancient square village of these shepherds was finallyrediscovered a few years ago.It did indeed overlook what was once an ordinary ford of an ordinary river, asluggish, chalky stream of water, ever dry in the summer, an obligatory passagefor flocks of sheep and goats…It is situated in Italy, a little further south than the land of the Etruscans, a littlefurther west than the land of the Sabines, and a little further north than the landof the Samnites…It lies beyond the River Tiber, on what remains of an old hill, called “Palatine”.They have told me they have returned.They live in the hearts and minds of the very many men and the very manywomen who still today seek to demonstrate in our courts that Ancient Law is notdead, as in the words uttered by an old Senator, when the sun was setting ontheir Republic, to a man named Catiline:…Quo usque tandem abutere patientia nostra ?There lies in this sentence, which lay buried for two thousand years, all thespirit of a Civilisation which perhaps we have not yet lost.And these words, perhaps, will once again resound in the halls of justice.Dott. Giuseppe Nacci338

Chapter 20NAMES OF PLANTS of medical interest that have orhave not been mentioned in the previous text.Note 1: possible contra-indications are not reported. The possible relative andabsolute contra-indications for the plants described only in the presentwork are reported in Chapter 18.Note 2: Common names are written in Italian, and /or English, and /or French, and/orDeutsch, and /or Spanish, and /or Japanese, and / or Chinese, and /or Sanskrit.1. Abelmoschus moschatus (or Hibiscus abelmoschus) : musk Mallow, Lataksturikam (Sanskrit)2. Abies alba[Abietaceae] : abete bianco3. Abies excelsa or Picea excelsa : Abete rosso4. Abies pectinata : Abete vero5. Abroma augusta : Cotone del Diavolo, Devil's Cotton, Abrome, Pinchaskarpas (Sanskrit)6. Abrus precatorius : Jequirity, Paternostererbsen (Deutsch), Gunja (Sanskrit)7. Abutilon vitifolium : Abutilo8. Acacia arabica, or nilotica, or indica : Albero di Babul, Babul Tree, Babool Baum, Babhoola (Sanskrit)9. Acacia catechu : Terra Cattù, Catecù; Catechu, Katechubaum (Deutsch), Cachoutier, Khadira (Sanskrit);10. Acacia farnesiana : Mimosa, Gaggia, Acacia falsa, Cassia (Italian and English), Akazie (Deutsch) (Sanskrit)11. Acacia horrida : Acacia del Senegal, Acacia gommifera, Acacaia della Gomma.12. Acalupha hispida : red-hot Cattail13. Acalypha indica : Ortica indiana, Ortica cinese, Ortica dell'Abissinia14. Acanthopanax senticosus (Eleuterococcus senticosus) : Ginseng siberiano, Eleuterococco15. Acca sellowiana : Feijoa16. Acantus mollis : Acanto17. Acer campestris canadensis : Acero canadese18. Achillea borealis : Yarrow19. Achillea clytedata : golden Yarrow20. Achillea herba-rota : Achillea Erba Rotta, Achillee blanche21. Achillea millefolium : Achillea Millefoglie, Erba del Soldato, Sanguinella, pink Yarrow, Achillee blanche22. Achillea moscata : Camomilla di Montagna23. Achillea nana : Achillea nana24. Achyrathes aspera : Achiranto, rough chaff Tree, Apamarga (Sanskrit)25. Achyrocline satureoides :Macela26. Aconitum delphinifolium : Monkshood (TOSSICO)27. Aconitum ferox : Aconito, Aconito indiano; indian Aconite; Wilder Sturmhut (Deutsch), Vatsanaba, (Sanskrit)(TOSSICO)28. Aconitum heterophyllum : Atees; Eisenhut (Deutsch), Ativisha (Sanskrit) (TOSSICO)29. Aconitum napellus : Aconito napello ((TOSSICO)30. Acorus calamus : Acoro, Calamo, Calamo aromatico; sweet Flang, sweet Rush; Kalmus (Deutsch), Vacha(Sanskrit);31. Actea spicata : Actea (Tossica)32. Actinidia chinensis : Kiwi33. Adhatoda vasica, zelanica (Justicia adhatoda): Malabar Nut; Malabar Nuss; Adotada (Japanese); Vasaka(Sanskrit).34. Adhyranthia bidentata : Adiranzia35. Adianthum capillus veneris : Adianto, Capovenere, Capelvenere36. Adianthum philippense, lunulatum : Felce di Capelvenere, Maiden-hair Fern, Hansaraj (Sanskrit)37. Adianthum podatum : Capelvenere del Canada38. Adlumia fungosa : Fumaria339

39. Adonis flammeus : Camomilla rossa(TOSSICO)40. Adonis vernalis ( or Ononis spinosa) : Anonide, Ononide, Ononide spinosa, Adonide (potenzialmente tossica)41. Adonxa moschatelina : Moschatel42. Aegle marmelos : bael Fruit, Bela-Fruchte (Deutsch), Bilva-shriphala (Sanskrit)43. Aesculus carnea : Ippocastano rosso , red Chestnut44. Aesculus hippocastanum : Ippocastano bianco, Castano d'India, white Chestnut .45. Aethusa cynapium : Cicuta minore (potenzialmente tossica)46. Agaricus bisporus : Mushroom, Mo Gu47. Agave americana : Agave48. Agnus castus (Vitex trifoglia; Vitex agnus castus) : Agnocasto, Pepe dei Monaci49. Agrimonia equatorium, eupatoria : Agrimonia, Erba vettonica; Agrimony50. Agropyrum repens : Gramigna, Dente di Cane, Grano delle Formiche51. Ailantus glandulosa : Ailanto, Albero del Paradiso52. Ajuga piramidalis : Aiuga53. Ajuga reptans : Bugula54. Alangium salviifolium, lamarkii : Foglia di Salvia; Sage Leaves, Ankola (Sanskrit)55. Albizzia lebbek : Siris, Shirish (Sanskrit)56. Alchemilla vulgaris : Alchimilla, Alchemilla, Erba rossa, Ventaglina57. Alchimilla alpina : Alchemilla argentina58. Alchornea castaneifolia : Iporuro59. Alhagi pseudalhagi, camelorum : Persischemanna (Deutsch), Jawasa (Sanskrit)60. Alisma plantago : Piantaggine d'Acqua o Mestolaccia61. Alliaria petiolata : Alliaria62. Alliaria officinalis : Alliaria63. Allium ascalonicum : Scalogno64. Allium cepa : Cipolla; Onion; Zwiebel; Oignon; Yang Cong (Chinese), Palandu (Sanskrit);65. Allium chinese : chinese Onion, Xie66. Allium fistulosum : spring Onions, Scallions, welsh Onion, Cong67. Allium porrum : Porro68. Allium sativum : Aglio, Garlic, Lauch, Ail, Suan (Chinese), Rasonam (Sanskrit)69. Allium schoenosprasum : Erba cipollina70. Allium tuberosum : chinese Chives, Jiu Cai71. Allium ursinum : Aglio orsino72. Allium vineale : Aglio delle Vigne73. Alnus crispa : Alder74. Alnus glutinosa : Alno, Ontano nero75. Alnus incana : Alno, Ontano bianco76. Alocasia macrorrhiza : Caladio a Grande Foglia, Great-leaved Caladium, Taro (Sanskrit)77. Aloe arborescens : Aloe africana, Aloe arborescente, Aloe del Capo; Kidachi Aloe.78. Aloe vera or barbadensis or ferox : Aloe vera, Aloe delle Barbados, Aloe delle Antille, Aloe indiana; indian Aloe,Subara, Luhui, Faigra, Kattavala, Rattabolam, Komarika, Kumari, Ghrit Kumari, Ghikanuar, Ghicuar, Kunhur(Sanskrit);79. Alpinia galanga, calcarata, officinarum : Galanga, Java glangal, Malayavach (Sanskrit);80. Alpinia officinarum : Galanga minore;81. Alstonia scholaris : Corteccia di Dita, Dita bark, Dita-Riude, Saptaparna (Sanskrit)82. Althaea officinalis :Altea, Bismalva, Malvaccione, Marsh-Mallow, Eibisch (Deutsch), Khatmi (Sanskrit);83. Althaea rosea : Malvarosa84. Altingia excelsa (Styrax officinalis) : Storace, Storax, Rasamala (Deutsch), Sillhaka (Sanskrit)85. Amaranthus caudatus : Love Lies Bleeding86. Amaranthus hypocondriacus : Amaranto; Amaranth; Amarante (French)87. Amaranthus retroflexus : Amaranto88. Amaranthus ticolor : Amaranth, Xian Cai89. Amaryllis zeylanicum (Crinum defixum, latifolium, asiaticum, bracteatum, toxicarium) : Tubero velenoso, poisonBulb, Gift-Zwiebel, Sudarshan (Sanskrit)90. Ammi maius : Rizzomolo91. Ammi visnaga : Visnaga92. Amomum subulatum : Grande Cardamomo; greater Cardamon, Kardmemeu (Deutsch), Elabari (Sanskrit)93. Amorphophallus campanulatus : Telgu potato, Kunda (Sanskrit)94. Ampelopsis quinquefolia : Vite del Canada95. Amygdalus communis (or Prunus amygadinus) : Mandorle, Mandorle dolci; Almond; Mandelbaum; Amandier;Badama (Sanskrit).96. Anacardium occidentale : Anacardio340

97. Anacyclus pyrethrum : Pellitory root, Speidetwurzel (Deutsch), Akarava ( Sanskrit)98. Anagallis arvensis : Anagallide, Bellichina (potenzialmente tossica)99. Anagallis caerulea : Occhi della Madonna100. Ananas sativus or comosus : Ananas, Pinneaple, Ananas (Sanskrit);101. Anchusa officinalis : Buglossa102. Andrographis paniculata : King of Bitters, Andrographis Kraut , Kirta (Sanskrit)103. Andromeda polifolia : bog Rosemary104. Anemone coronaria : Anemone, Anemolo (potenzialm. tossica).105. Anemone hepatica : Erba del Tron, Erba Trinità, Occhi di Gatto (potenzialmente tossica)106. Anemone hortensis : Fiore Stella(TOSSICO)107. Anemone nemorosa : Anemone dei Boschi (potenzialmente tossica)108. Anemone pulsatilla (or Pulsatilla nigricas) : Anemone dei Prati (potenzialmente tossica)109. Anethum foeniculum (Foeniculum vulgare, capillaceum) : Finocchio selvatico, Anice dolce, Erba buona, Fennel,Garten Feuchel (Deutsch), Uikyo (Japanese), Hui-hsiang (Chinese), Satupuspa (Sanskrit).110. Anethum graveolens o Peucedanum graveolens: Aneto, Finocchio bastardo, Finocchio fetido; Dill; Shi Luo(Chinese), Aneth (French)111. Anethum sowa (Peucedanum graveolens) : indian Dill (English); garten Dill; Indndo (Japanese); MisroyaSatapushpi (Sanskrit).112. Angelica archangelica or officinalis : Arcangelica, Erba degli Angeli, Erba dello Spirito Santo, Erba di Boemia,Angelika; Angelique113. Angelica dahurica : Daurica114. Angelica glauca : Glauca, Angelica, Angelika, Choraka (Sanskrit)115. Angelica silvestris : Angelica, Angelika116. Angelica sinensis : Dong Quai117. Aniba roseadora : Bois de Rose118. Anigozanthos manglesii : purple and red, red and green Kangaroo Paw119. Anigozanthos humilis : Catspaw120. Annona muricata : Guanàba,Graviola121. Annona squamosa : Custard apple , Zuckerapfel, Sitaphalam (Sanskrit)122. Antennaria dioica : Sempiterni123. Anthemis arvensis : Camomilla falsa124. Anthemis cotula : Camomilla, Chamomille125. Anthemis nobilis : Camomilla romana, Antemide, Appiolina, Bambagella, Camomilla Inglese, Camomilla diBoemia126. Anthyllis alpestris or vulneraria : Vulneraria; Kidney-Vetch, Lady’s-Finger127. Anthriscus cerefolium : Cerfoglio128. Antirrhinum majus : Gola di Lupo; Snapdragon (English); Goule de Loup (French)129. Anthocephalus indicus, cadamba : Wild cinchona, Kadamb, Katamba (Sanskrit)130. Aphanizomenon flosaquae [Algae] : Alghe di Klamath131. Apium graveolens : Sedano selvatico, Appio dolce, Appio palustre, Appio delle Paludi, Celery, Sellerie, Ajmoda,Han Qin132. Apium graveolens rapaceum : Sedano-Rapa133. Apium graveolens dulce : Sedano da Coste134. Apium petroselinum (Petroselinum hortense or Carum petrioselinum) : Prezzemolo135. Aquilaria agallocha : Aquilaria, Aloe Wood, Adperhopz (Deutsch), Agalloche, Agaru (Sanskrit)136. Aquilegia formosa : Columbine137. Aquilegia vulgaris : Aquilegia, Amor nascosto(TOSSICO)138. Arachis hypogaea : Nocciolina americana, Spagnoletta, Peanut, Groundnut, Hua Sheng (Chinese)139. Aralia racemosa, quinquefolia : Aralia, Nardo americano140. Araucaria imbricata : Araucaria141. Arbutus unedo : Corbezzolo, Albatro, Rossello142. Arctium lappa : Bardana, Erba tignosa, Lappa, Lappola, Lappolaccio143. Arctostaphilos uva ursi : Uva ursina, Ramoliva, Uva dell'Orso144. Arctostaphilos viscida : Manzanita145. Areca catechu : Areca; Areca nut; Betelnusse; Arequier-Nox d'arec; Pooga (Sanskrit)146. Argemone mexicana : Argemone messicana, yellow Thistle, Prickly Poppy, mexican Poppy, Stachel Mohn(Deutsch), Satyanasi (Sanskrit).147. Argyreia speciosa ( or Lettsomia nervosa) : Elephant creeper, Vridha daraka (Sanskrit)148. Arisarum vulgare [Araceae] : Arisaro, Gilico149. Aristolochia bracteata : Wormkiller, Aristoloch (Deutsch), Kitamari (Sanskrit) (TOSSICO)150. Aristolachia chilensis : Erba della Vergine (TOSSICO)151. Aristolochia clematitis, trilobata : Aristolachia, Stralloggi (TOSSICO)341

152. Aristolachia elegans or littoralis : Aristolachia (TOSSICO)153. Aristolochia gigantea : Noaro(TOSSICO)154. Aristolachia grandifolia, gigas : Aristolachia(TOSSICO)155. Aristolochia indica : Indian birthwort, Indische Ostertuzei, Ishwari, Sunanda (Sanskrit). (TOSSICO)156. Aristolochia rotunda : Erba astrologa(TOSSICO)157. Aristotelia maqui : Aristotelia158. Aritiguitia bollii :Asmachilea159. Armoracia rusticana (Cochlearia armoracia ) : Rafano, Cren, Barbaforte; Radish(English)160. Arnica montana, mollis : Arnica, Panacea delle Cadute, China dei Poveri;Arnica (French)161. Artemisia abrotanum : Abrotano162. Artemisia absinthium : Assenzio, Assenzio maggiore, Assenzio romano163. Artemisia cina : Fiori di Santonico164. Artemisia douglassiana : Mugwort165. Artemisia dracunculus : Dragoncello, Estragone, Tarragon(English)166. Artemisia genipi : Genepì maschio, Genepì nero167. Artemisia glacialis : Genepi168. Artemisia lactiflora : duck foot Vegetable, Ya Jiao Cai169. Artemisia maritima, brevifolia : Worm seed, Meersrand Beiful (Deutsch), Chauhar (Sanskrit)170. Artemisia mutellina : Genepi171. Artemisia pontica.: Assenzio pontico o gentile (tossico)172. Artemisia tilesii : mountain Wormwood173. Artemisia tridentata : Artemisia tridentata, Sage-brush174. Artemisia spicata : Genepi175. Artemisia vulgaris : Artemisia, Amarella, Fiore di Santa Giovanna, Mugwort, Indian Worm-wood, Beiful(Deutsch), Nagadamni (Sanskrit);176. Artocarpus integrifolia , heterophyllus : indian Jack, Indischerbrod (Deutsch), Panasa (Sanskrit)177. Arum maculatum Aro, Gighero, Gigaro, Giaro, Pan di Serpe (Tossica)178. Arum triphyllum : Rapa indiana179. Arundo donax : Canna comune, Canna rigata180. Arundo phragmites : Canna di Palude181. Asarum europaeum : Baccaro182. Assa foetida (or Ferula) : Assa fetida183. Asclepias cordifolia : Milkweed184. Asclepias gigantea (Calotropis gigantea) : Mudar, bowstring hemp, Herbe Lirondelle, Alarka (Sanskrit)185. Asclepias tuberosa : Cotone d'Egitto tuberoso, Radice da Pleurite, Pleuresy-root186. Asparagus acutifolium : Asparago spinoso187. Asparagus adscendens : Musli188. Asparagus cochinensis : Asparago cinese,Tian Men Dong189. Asparagus officinalis, racemosus : Asparago, Asparagus, Spargel, Asperge, Shatavari (Sanskrit);190. Asperula odorata : Asperula, Stellina odorosa191. Aspidosperma quebracho : Quebraco192. Asphodelus albus : Asfodelo, Porraccio193. Asplenium trichomanes : Asplenio, Erba rugginina194. Aster alpinus : Astro delle Alpi195. Asteracantha longifolia (Hygrophila auriculata) : Langblathriger Sterndorn (Deutsch), Kokilaksha (Sanskrit).196. Astragalus chrysopterus : Astragalo197. Astragalus floridus : Astragalo198. Astragalus membranaceus : Astragalo199. Astragalus tongolensis : Astragalo200. Atractylodes ovata201. Atriplex hortensis : Atriplice202. Atropa acuminata : Belladonna indiana; indian Belladonna, Tolkkivacha (Deutsch), Suchi (Sanskrit) (moltotossica)203. Atropa belladonna : Belladonna (molto tossica)204. Auricularia auricula : wood Ear, Mu Er (Chinese)205. Avena sativa : Avena; Oats (English)206. Averrhoa carambola : Chinese gooseberry, Karmaranga (Sanskrit)207. Azadirachta indica, Melia azadirachta : Albero sacro, Persian Lilac, Indischer Zedrach, Margousier, Arishta,Nimba, Neem (Sanskrit).208. Baccharis rosmarinifolia or genistelloides : Baccaride209. Bacopa monniera, Herpestis monniera, Monniera cuneifolia : Bacopa, Brahmi (Sanskrit);210. Bactris gasiaes : Contaduro, Chontaduro342

211. Bauhinia forficata :Pata de Vaca212. Balanites aegyptiaca or roxburghii : Ingudi-vraksha (Sanskrit)213. Baliospermum montanum : Danti214. Ballotta foetida (or nigra) : Marrubio fetido215. Balsamita major : Erba di San Pietro, Erba della Bibbia, Erba amara216. Balsamodendron mukel (Commiphora mukul) : Mirra, Gum gugal, Myrrhe (Deutsch), Guggulu (Sanskrit).217. Balsamum peruvianum : Balsamo del Perù.218. Balsamum toluiferum : Balsamo di Tolù.219. Bambusa arundinacea, bambos : Bamboo, Bambus (Deutsch), Bambou commun, Vasna (Sanskrit)220. Bambusa beecheyana : bamboo Shoot, Tian Zhu (Chinese).221. Banskia menziesii : menzies Banskia222. Baptisia tinctoria : Indaco selvatico223. Barleria prionitis : Kurantaka (Sanskrit)224. Barringtonia acutangula : Hijjala (Sanskrit)225. Basella rubra : Basella, ceylon Spinach, La Kui (Chinese)226. Bassia longifolia (Madhuca longifolia) : indian Butter Tree; Madhuka (Sanskrit)227. Bauhinia forficata : Pata de Vaca228. Bauhinia tomentosa : Mountain Ebony, Aswamantaka (Sanskrit)229. Bauhinia variegata : Kanchanara (Sanskrit)230. Bellis perennis : Pratolina, Margheritina; Paquerette (French);231. Benincasa hispida, cerifera : Zucca bianca, winter Melon, wax Gourd, white Pumpkin, Wachsgurkensamen(Deutsch); Dong Gua (Chinese); Courge (Sanskrit).232. Berberis aquifolium : Oregon Grape233. Berberis aristata, floribunda, coriaria : Turmeric, Berberitze, Daruharidra.234. Berberis vulgaris : Crespino, Spina acida, Spino santo, Berberi, Berbero, Uva spinetta .235. Bergenia ligulata (Saxifraga ligulata) : Steinbrech (Deutsch), Pashanbheda (Sanskrit).236. Bertholletia excelsa :Noce del Brasile237. Beta vulgaris : Barbabietole ; sugar beets238. Beta vulgaris cruenta : Barbabietole rosse239. Beta vulgaris var. cycla : Bieta; swiss Chard, Leaf-Beet, Jun Da Cai240. Betonica officinalis (or Stachys officinalis) : Betonica241. Betula alba : Betulla bianca, Betulla pelosa242. Betula papyrifera : paper Birch243. Betula utilis : Birch, Birke, Bhurjapatra (Sanskrit)244. Bidens pilosa : Picao Preto245. Bigonia catalpa : Bigonia246. Bixa orellana : Annatto247. Blepharis edulis : Utangan (Sanskrit)248. Blumea lacera : Blume, Blumecampher, Kukurandru (Sanskrit)Boerhaavia diffusa : Spreading hogweed, Punarnava (Deutsch), Herlee a cochons (French), Erva tostagno(Espanol),Punarnava249. Bombax buonopozense : Papula250. Bombax ceiba : Silk cotton Tree, yellow silk Cotton; Malabarischer wollbaum (Deutsch), Kapokur (Sanskrit).251. Borassus flabellifer, flabelliformis : Palma di Palmira, Palmyra Palm, Palmyrapalm (Deutsch), Tala (Sanskrit)252. Boronia megastigma : brown Boronia253. Barosma crenulata : Bucco254. Borrago officinalis (Borago officinalis) : Borragine, Borrana, Lingua rada; Borage (English); Bourrache (French);255. Boswellia serrata : indian Olibaum, Salaibaum, Bswellie-dentee, Shallaki256. Bouganvillaea : Bouganvillaea257. Brasenia schreberi : Watershield, Chun Cai258. Brassica alboglabra (it’s variety of Barassica oleracia) : chinese Kale, Gai Lan259. Brassica campestris (var. oleifera) : chinese Cabbage, bird Rape, Flowering, You Cai260. Brassica caulorapa : Kohlrabi , Qiu Jinig Gan Lan261. Brassica juncea : Senape indiana; brown Mustard, leaf Mustard, indian Mustard, chinese Mustard, Gai Cai(Chinese), Grunersenf (Deutsch), Rajika (Sanskrit)262. Brassica napus : Ravizzone263. Brassica nigra : Senape nera264. Brassica oleracea : Cavolo, Cabbage, Cauliflower, Gan Lan265. Brassica oleracea botrytis : Cavolfiore; Cauliflower266. Brassica oleracea bullata or gemmifera : Cavoletti di Bruxelles267. Brassica oleracea capitata : Cavolo-Cappuccio verde268. Brassica oleracea botrytis or italica : Broccoli343

269. Brassica pekinensis : chinese Cabbage, Bai Cai270. Brassica rapa, campestris : Rapa ;Turnip(english)271. Brayera anthelmithica (or Hagenia abyssinica) : Braiera o Cusso272. Briza maxima : quaking Grass273. Bromus ramosus : Avena selvatica, wild Oat274. Bromus stamineus : Bromo275. Brunfelsia uniflorus : Manacà276. Bryonia alba : Brionia bianca277. Bryonia dioica : Brionia, Zucca matta (potenzialmente tossica)278. Buddleja species : yresine weberbrueri (English), Flor blanco (Espanol).279. Bupleurum stellatum : Orecchio di Lepre280. Buchanania lanzan, latifolia : Cuddapa almond, Chirongiol (Deutsch), Piyala (Sanskrit)281. Butea frondosa, monosperma : Legno bastardo; Parrot, bastard Teak; Palasbaum (Deutsch), Palasa (Sanskrit).282. Buxus chinensis : Bosso cinese283. Buxus sempervirens : Bosso; Buis284. Cactus grandiflorus : Regina della Notte285. Caenomeles speciosa : Quince286. Caesalpina bonducella, bonduc, crista : Noce di Bonducella, Bonducella Nut, Kugelstrauch Samen, Latakaranja(Sanskrit)287. Caladenia aphylla : leafless Orchid288. Caladenia dilitata : fringer mantis Orchid289. Caladenia flavia : cowslip Orchid290. Caladenia gemmata : blue china Orchid291. Caladenia latifolia : hybrid pink Fairy, pink fairy Orchid292. Caladenia menziessi : rabbit Orchid293. Caladenia patersonii : Orchidea del Ragno bianco; white Spider Orchid294. Calamintha nepeta or sylvatica : Mentuccia, Nepetella, Poleggio295. Calamintha officinalis : Calaminta296. Calandrinia discolor : Calandrina297. Calandrinia polyandra : Parakeelya298. Calectasia (or Ornithogalum umbellatum) : Stella di Betlemme; Star of Bethlehem299. Calendula officinalis : Calendula, Calendola, Calta, Fiorrancio, Fioraccio, Garofano di Spagna; Calendula(English);300. Calendula silvestis: Calendula301. Calicopteris floribunda : Ukshi302. Calliandra surinamensis : Tassel303. Callicarpa macrophylla : Pringu (Sanskrit)304. Callistemon polandi : queensland Bottlebrush305. Calluna vulgaris : Scopiccio, Brentolo, Brugo, Brughiera, Erica, Heather306. Calochortus albus : Lanterna delle Fiabe; fairy Lantern307. Calochortus lechtlinii : Giglio di Mariposa; Mariposa Lily308. Calochortus monophylius : yellow star Tulip309. Calochortus tolmiei : star Tulip310. Calophyllum inophyllum : Albero di Pannay, Pannay Tree, Tacama Hacharz (Deutsch), Laurier d'Alexandria,Punnaga (Sanskrit)311. Calothamnus myrticae : one-sided Bottlebrush312. Calotropis gigantea (Asclepias gigantea) : Canapa da Corda, Mudar, Swallow Wart, bowstring Hemp, HerbeLirondelle, Alarka (Sanskrit)313. Calotropis procera : Mudar, Aeribe hirondeille, Arbre-a-sofa, Arka (Sanskrit)314. Calycophyllum spruceanum : Mulateiro315. Camellia sinensis : The verde; green Tea(english)316. Campanula barbata : Campanula barbata317. Campanula lasiocarpa : Harebell318. Campanula latifolia : Arcangelica319. Campanula rapunculus : Raperonzolo320. Campanula trachelium : Imbutini321. Campsis tagliabuana : trumpet Vine322. Cananga odorata, genuina : Cananga, Ylang ylang323. Canarium album : Chinese olive, Lan Chi (Chinese)324. Canavalia gladiata : sword Bean, Dao Dou325. Canavalina ensiformis : Fagiolo nero, Fagiolo rosso, Fagiolo messicano; Mexican beans326. Cannabis sativa : Canapa indiana (tossico)344

327. Capparis spinosa : Capperi328. Capsella bursa pastoris : Capsella, Borsa del Pastore; shepherd’s Purse, Ji Cai (Chinese)329. Capsicum frutescens or annuum : Capsico, Peperoncino rosso, Peperoncino piccante, Pepe di Caienna, Paprika,Spanish pepper, Cayenne, hot Peppers, Chilli, cayenne Pepper, Paprika , Paptika (Deutsch), Pimment annuel, LaJiao (Chinese), Katuvira (Sanskrit);330. Caralluma negevensis : Caralluma (Tossica)331. Carapa guianensis : Andiroba332. Cardamine pratensis : Cardamine333. Carduus defloratus : Cardo rosso334. Carduus marianus (or Silybum marianum) : Cardo mariano, Cardo di Maria, Cardo asinino, Cardo lattato .335. Careya arborea : slow Match336. Carex arenaria : Carice337. Carica papaya : Papaia, Papaya, Papaw, Melonenbaum (Deutsch), Fan Mu Gua (Chinese), Popayer commun(Sanskrit)338. Carlina acaulis : Carlina339. Carthamus tinctorium : Cartamo340. Cardamine pratensis : Cardamine341. Carinus betulus : Carpino, Hornbeam342. Carpinus betulus : Carpino bianco343. Caryophyllus aromaticus :Garofano,o Chiodo di Garofano344. Carum carvi : Carvi, Cumino dei Prati, Comino dei Prati, Cumino bianco, Cumino tedesco, Comino tedesco,Cumin, Caraway, Gemeiner Kummel (Deutsch), Cuminnoir, Krishna jira (Sanskrit);345. Carum nigrum (Nigella sativa) : Melanzio nero, Cumino nero, Comino nero; black Cumin; Schwarzkummel;Cumin noir; Nigera (Japanese); Upakunchika (Sanskrit);346. Carum copticum (Trachyspermum ammi, Ptychotis ajowan) : Aiovano, Omum, Ajowan Kummel, Yamani347. Carum petrioselinum (or Apium petroselinum or Petroselinum hortense) : Prezzemolo348. Cassia absus : Chaksu (Sanskrit)349. Cassia angustifolia (or acutifolia, or obovata): Senna indiana, Senna Tinnevelly; Tinnevelly Senna, Indian Senna,Sennes Blatter, Markandika (Sanskrit); .350. Cassia fistula : Cassia cava, Cassia purgativa, Laburno indiano; indian Laburnum, Rohrkassie, Cassie purgative,Argbhada (Sanskrit); .351. Cassia foetida (or obtusifolia, tora, toroides) : Cassia fetida, Fetid Cassia (Sanskrit).352. Cassia occidentalis : Cassia occidentale, Caffè nero, Negro coffee, coffee Senna, Rinde-Tedegoso (Deutsch),Cassier, Wangjiang Nan (Chinese), Kasmard (Sanskrit).353. Castanea sativa : Castagno dolce; sweet Chestnut .354. Castanea vesca : Castagno; Chestnut.355. Castilleja minata : Pennello indiano; indian Paintbrush.356. Catharanthus roseus: (TOSSICO)357. Cayaponia tayuya : Tayuya358. Ceanothus integerrimus : deer Brush359. Cedrus libani, deodora (or Pinus deodara) : Cedro del Libano, Deodar, Cedre deodar (Sanskrit)360. Celastrus montana, multiflora, nutans, paniculatus : Albero del Bastone; Staff tree, Dudukol Celasterol (Deutsch),Kanguni361. Centaurea cyanus : Fiordaliso, Ambretta, Muneghetta362. Centaurea erythreum : Centaurea363. Centaurea solstitialis : star Thistle364. Centaurium umbellatatum : Cacciafebbre, Centaury1) Centella asiatica : Centella, asiatic Centella, Lei Gong Gen (Chinese)365. Centratherum anthelminticum (Vernonia anthelminticum) : Vernonia, Aranjajira (Sanskrit)366. Cephaelis ipecacuanha : Ipecacuana367. Cerastium alpinum : Cerasio368. Ceratonia siliqua : Carruba ; Carob (english)369. Ceratostigma wilmottiana : Cerato370. Cercis siliquastrum : Albero di Giuda371. Cereus giganteus : Saguaro372. Cerinthus minor : Erba Tortora373. Cestrum diurnum : Day blooming jessamine374. Ceterach officinarum : Spaccapietra, Cedracca, Erba ruggine, Erba dorata375. Cetraria islandica (or Lichen islandicus) : Lichene islandese376. Chaenomeles speciosa : Quince377. Chamaelirium luteum : Elonia378. Chamelaucium uncinatum : geraldton Wax345

379. Chamomilla recutita : Camomilla380. Chamaedaphne calyculata : Cassandra381. Cheilanthes pruinata :Kuti-Kuti382. Cheirantus cheiri : Violaciocca383. Chelidonium majus : Chelidonia, Celidonia, Erba porraia, Erba nocca, Erba da Porri Ukrain (TOSSICO)384. Chenopodium album : Farinaccio; Lamb's Quarters385. Chenopodium ambrosioides : Chenopodio, Ambrosia, The messicano, Mexican tea, Scho Kraut, Sugandhavastuk(Sanskrit)386. Chenopodium bonus henricus : Buon Enrico387. Chimaphila umbellata : Pirola ombrellifera, Chimafilla388. Chrysantellum americanum : Crisantemo americano389. Chrysanthemum balsamita : Balsamite odorosa, Erba di San Pietro390. Chrysanthemum leucanthemum : Margherita391. Chrysanthemum maximum : shasta Daisy392. Chrysanthemum morifolium : Crisantemo, Chrysanthemum393. Chrysanthemum segetum : Crisantemo, Ingrassabue; Chrysanthemum, Carland; Tong Hao Cai (Chinese)394. Chrysothamnus nauseosus : Rabbitbrush395. Cicer arietinum : Ceci; chick peas396. Cicerbita alpina Lattuga alpina397. Cichorium intybus : Cicoria, Cicoria selvatica, Radicchio, Cicorella; Chicory, Zichorie (Deutsch); Hasni ;398. Ciclamen europaeum : Ciclamino399. Cicorium endivia latifolium : Endivia400. Cicuta virosa : Cicuta acquatica, Cicuta minore (molto tossica)401. Cimicifuga racemosa : Cimifuga; black Cohosh402. Cinchona calisaya or micrantha, or legderiana, or officinalis, or succirubra : China403. Cinnamomum camphora : Canfora; Camphor; Kampher (Deutsch); Camphre; Karpoor (Sanskrit)404. Cinnamomum cassia, or zeylanicum : Cannella, Cannella bella, Cannella di Ceylon, Cannella del Madagascar;Cinnamon; Zimt; Cannelle; Nikkei (Japanese), Twak (Sanskrit);405. Cinnamomum tamala : Cassia cinnamomon; Zimtbaum; Cannelle; Tejpatra (Sanskrit)406. Cirsium arvense : Scardaccione407. Cirsium spinosissimum : Spinon408. Cirsium vulgare : Cirsio, Scardaccione409. Cissampelos pareira : Pareira, Foglia vellutata; Velvet Leaf; Talsche Pareivawurzel (Deutsch), Pareira (Japanese),Laghu Patha (Sanskrit)410. Cissus quadrangularis (Vitis quadrangularis, Heliotropium indicum) : Conciaossa; Bone Setter, Dixanh young(Chinese), Asthisanhari (Sanskrit)411. Cistus incanus : Rosalaio412. Citrullus colocynthis : Coloquintide, Mela amara; bitter Apple, Koloquinte, Conchomlere amer, Koroshinto(Japanese), Hsikua (Chinese), Indravaruni (Sanskrit) (TOSSICO)413. Citrullus vulgaris : Cocomero, Anguria, Melone rosso; Pasteque (French).414. Citrus aurantium : Arancia415. Citrus aurantium bergamia : Bergamotto416. Citrus decumana , or grandis : Pompelmo417. Citrus deliciosa : Mandarino418. Citrus limonium, or medica : Limone; Citronner (French)419. Claviceps purpurea (or Secale cornutum) : Segale cornuta420. Clematis recta : Clematide retta, Fiammola421. Clematis vitalba : Vitalba; Clematis(TOSSICO)422. Clerodendrum infortunatum : Bhandira (Sanskrit)423. Clitoria ternatea : Butterfly pea, Clitore-deternate (French), Chomama (Japanese), Aparajita (Sanskrit)424. Cnicus benedictus : Cardo santo, Cardo benedetto, Erba benedetta.425. Coccinia indica, cordifolia, grandis : Bimba (Sanskrit)426. Cochlearia armoracia (Armoracia rusticana) : Rafano, Cren, Barbaforte; Radish(English)427. Coclearia officinalis : Coclearia; Radish(English)428. Cocos nucifera : Noce di Cocco; Coconut plant; Echte kokospalme (Deutsch), Coctier, Yashi (Japanese), Narikela(Sanskrit)429. Codonopsus pilosula430. Coffea arabica : Caffè verde431. Cola acuminata : Noce di Cola432. Colchicum autumnale : Colchico, Freddolina, Falso Zafferano (molto tossico).433. Colchicum luteum : Collirio d'Oro, Golden Collyrium, Gelbe Herbastzeitlose, Hiranyatutha (Sanskrit); (moltotossico)346

434. Collinsonia canadensis (Pareira brava ) : Radice di Pareira435. Colutea arborescens : Erba vescicaria436. Combretum caffrum : Salice africano437. Combretum micranthum : Combreto438. Commiphora mirra : Mirra439. Commiphora mukul (Balsamodendron mukul) : Gum gugal, Myrrhe (Deutsch), Guggulu (Sanskrit)440. Commiphora gileadensis : Mirra441. Conium maculatum : Cicuta maggiore (molto tossica)442. Conospermum stoechadis : west australian Smokebush443. Conostylis aculeata : yellow Cone444. Consolida regalis : Speronella, Erba cornetta. (TOSSICO)445. Convallaria majalis : Convallaria, Mughetto (tossica)446. Convallaria polygonatum (or Polygonatum officinale) : Poligonato, Sigillo di Salomone447. Convolvulus arvensis : Vilucchio448. Convolvulus turpethum (Ipomoea turpethum; Operculina turpethum) : indian Jalap; Brast Liauische; Trivrit(Sanskrit).449. Convolvulus purga : Convolvolo purgativo450. Convolvolus scammonia : Scammonea451. Convolvulus sepium : Vilucchio bianco, Campanello, Vilucchione452. Copaifera officinalis :Copaiba453. Coptis teeta : Gold thread, Mishamitika (Sanskrit)454. Corallina officinalis : Corallina di Corsica455. Cordia myxa : Cordia, Sebesten plum, Cordia (Deutsch), Seleastan (French), Sleshmataka (Sanskrit)456. Coriandrum sativum : Coriandolo, Erba cimice, Coriander, Gemeiner coriender (Deutsch), Biles cereales (French),Yan Sui (Chinese), Dhanyaka (Sanskrit) .457. Corylus avellana : Nocciolo, Avellana; hazelnuts(English)458. Corynanthe yohimbe : Yohimbe459. Cornus canadensis : Bunchberry460. Cornus mas : Corniolo461. Cornus sanguinea : Sanguinello462. Cornus nuttalii : Legno di Cane, Dogwood463. Correa pulchella : Correa (Italian and English)464. Corylus avellana : Nocciolo465. Cosmos bipinnatus : Cosmos466. Costus speciosus : Costus, Pritge Kostwurz (Deutsch), Costus elegant (French), Kemuka (Sanskrit)467. Courouptia guaianensis : cannon Ball468. Crassocephalum crepidioides : false crowndaisy Chrysanthemum, Jia Tong Hao469. Crataegus azarolus Azzeruola470. Crataegus oxyacantha or monogyna : Biancospino, Bossolino, Spino bianco; Thorn-tree, Hawhorn; Aubepine(French)471. Crepis aurea : Radichella amara472. Crepis vesicaria : Crepide473. Crinum defixum, latifolium, asiaticum, bracteatum, toxicarium (Amaryllis zeylanicum) : Tubero velenoso; Nilgirilongy St. John's Iliy, Cape Iily, poison Bulb; Gift-Zwiebel, Indohamayu (Japanese), Sudarshan (Sanskrit)(TOSSICO)474. Crithmum maritimum : Finocchio di Mare, Bacicci, Cretamo475. Crocus sativus : Zafferano, Castagnole, Croco; Saffron; Safran; Kumkumapu (Japanese), Fan Hunghau (Chinese),Kumkuma (Sanskrit)476. Crocus vernus : Zafferano selvatico477. Croton draconoides or lechleri : Sangue di Drago; Sangre de Grago (TOSSICO)478. Croton eluteria : Eleuteria, Cascarilla (TOSSICO)479. Croton oblongifolium : Croton lungo; Nagdanti (Sanskrit) (TOSSICO)480. Croton philippensis (Mallotus philippensis) : Rottlera (English); Kamala (Deutsch); Kamola (French); Kampillaka(Sanskrit). (TOSSICO)481. Croton tiglium : Crotonolo, Croton, Crotontiglio; Purgative-Croton; Krotonol (Deutsch); Huile dectiglium(French), Hazu (Japanese), Jayapala (Sanskrit) (TOSSICO)482. Cucumis melo : Melone; Melon483. Cucumis sativus : Cetriolo, Common-Cucumber; Gurke (Deutsch); Kyuri (Japanese); Huang Gua (Chinese);Trapusha (Sanskrit);484. Cucurbita maxima or moscata : Zucca, Cocuzza; Pumpkin, Nan Gua (Chinese)485. Cucurbita pepo : Zucchine; Courgette, zucchini/courgettes347

486. Cuminum cyminum : Cumino romano, Comino romano, Cumin-Seed, Kumin, Kreuz Kummel, Anisacre (French),Kumin (Japanese), Jeeraka (Sanskrit);487. Cupressus sempervirens : Cipresso488. Curculigo orchiodes : Musli nero, Musli di Kalì, black Musalie, Kinbai zassa (Japanese),Talamulika (Sanskrit)(TOSSICO)489. Curcuma amada : Zenzero di Mango, Mango-Ginger, Mangeingwer (Deutsch), Karpura haridra (Sanskrit)490. Curcuma angustifolia : Appretta di Curcuma, Curcuma-Starch, Schmal-blattrige Kurkume (Deutsch), Tavakshiri(Sanskrit)491. Curcuma longa, domestica : Curcuma, Zafferano delle Indie, Zafferano dei Poveri, Turmeric, KurkumaGelbwurzel (Deutsch), Ukon (Japanese), Yii-chin (Chinese), Haridra (Sanskrit);492. Curcuma xanthorrhiza : Curcuma493. Curcuma zedoaria : Zedoaria, Zedoaria rotonda, Round-Zedoary, Zittwer (Deutsch), Zedoaire long (French),Gajutsu (Japanese), Shati (Sanskrit);494. Cuscuta chinensis : Cuscutacinese495. Cuscuta corymbosa : Cuscuta496. Cuscuta epithymum : Cuscuta497. Cuscuta reflexa : Cuscuta; Dodder; Amaravela (Sanskrit)498. Cusparia febrifuga or officialis (or Galipea officialis) : Angostura499. Cyamopsis tetragonolobus : Guar500. Cyanicula amplexans : shy blue Orchid501. Cyclamen europaem : Ciclamino502. Cyclamen neapolitanum : Ciclamino o Porporino503. Cyclanthera pedata : Caigua504. Cydonia oblonga, vulgaris : Mela Cotogna, Cotogno; Cognassier505. Cymbopogon citratus : Verbena delle Indie,506. Cymbopogon nardus : Citronella,507. Cynancum vincetoxicum : Vincetossico508. Cynara cardunculus : Cardo509. Cynara scolymus : Carciofo, globe Artichoke510. Cynodon dactylon : Erba del Cane; Dog Grass, Wucherndeu Hundszahn (Deutsch), Chiendent (French),Kyogishiba (Japanese), Doorwa (Sanskrit)511. Cynoglossum grande : Cinoglosso, Lingua di Segugio; Hound's Tongue512. Cyperus rotundus : Erba Noce, Nut Grass, Grasmandel, Souchet, Hamasuge (Japanese), Hiang Fou (Chinese),Mustaka (Sanskrit)513. Cyphomandra betacea : Tamarillo514. Cyprepedium guttatum or parviflorum : Lady's Slipper515. Cypripedium passerinum : northern Lady's Slipper516. Cypripedium pubescens : Cipripedio517. Cytisus laburnum : Avorniello518. Cytisus scoparius : Ginestra dei Carbonai (tossica)519. Dactylorhiza sambucina : Orchidea sambucina520. Dahlia variabilis : Dalia521. Dampiera linearis : Dampiera522. Daphne laureola : Laureola (molto tossica)523. Daphne mezereum : Dafne, Mezereo (Tossica)524. Darlingtonia californica : Darlingonia; california pitcher Plant525. Datura alba, metal : Mela spinosa, Tromba degli Angeli; Thornapple, Angel's Trumpet; Weichhaaariger Stechapfel(Deutsch), Pomme epineuse (French), Yoshuchosen asaga (Japanese), Chan kiue Tse (Chinese), Dattura (Sanskrit).526. Datura candida : Tromba degli Angeli; Angel's Trumpet527. Datura stramonium : Stramonio, Erba del Diavolo, Noce spinosa (molto tossica)528. Daucus carota : Carota selvatica, Pizzo della Regina Anna (Fiore); Carrot, Queen Ann's Lace; Karotte (Deutsch),Garotte cultive, Carotte sauvage (French), Hu Luo (Chinese) Bo Ninjin (Japanese), Garijara (Sanskrit)529. Davieasa divaricata : orange spiked Pea530. Delphinium ajacis : Speronella, Fior Cappuccio531. Delphinium denudatum : Ritterspoon (Deutsch), Nirvishi (Sanskrit)532. Delphinium depauperatum : Larkpur533. Dendrobium macraei (Ephemerantha macraei) : Jivanti (Sanskrit)534. Dentaria enneaphyllos : Dentaria535. Deonix regia : Gulmohar536. Desmodium ascendens : Desmodio537. Dianthus barbatus : Garofano a Mazzetti538. Dianthus monspessulanus : Garofanino348

539. Dicentra chysantha : golden ear Drops540. Dicentra formosa : bleeding Heart541. Dicleptera chinensis : dog liver Vegetable, Gou Gan Cai (Chinese)542. Dictamus albus : Dittamo, Frassinella, Limonella.543. Digitalis purpurea : Digitale; Foxglove, Roter Fingerhut (Deutsch), Mao-ti-huang (Chinese), Hatapatri (Sanskrit);(molto tossica)544. Dillenia indica, speciosa : Chalta (English), Biwamodoki (Japanese), Dok shan (Chinese), Avartaki (Sanskrit)545. Dioscorrea bulbifera, crispata, pulchella, sativa, versicolor : Igname; Yam; Brotwurel, Barahi (Sanskrit)546. Dioscorrea hypoglauca : Bie Xie547. Dioscorrea opposita : chinese Potato, Chinese Yam, Shan Yao548. Dioscorrea villosa : Igname selvatico, Wild Yam549. Diospyros kaki : Cachi550. Diplotaxis tenuifolia : Diplotaxide, Ruchetta selvatica551. Dipsacus fulloum : Cardo dei Lanaioli552. Dipterocarpus indicus, turbinatus, laevis, alatus : Albero dell'Olio di Bosco, Wood Oil Tree, Gurjunbalsam(Sanskrit).553. Diuris longifolia : wallflower donkey Orchid554. Dodanaea viscosa : hops Bush555. Dodecatheon frigidum : shooting Star556. Dodecatheon hendersonii : shooting Star557. Dolichos biflorus, uniflorus : Ceci di Cavallo, Horse Gram, Pferde Bohne (Deutsch), Dolique (French), Kulitha(Sanskrit).558. Draba aizoides : Draba559. Dracontium loretense : Sacha560. Drimys chilensis, or winteri : Drimide561. Drosera rotundifolia, or anglica, or intermedia : Drosera, Rosolida, Rugiada del Sole; roud-leaved Sudew .562. Drosera pallida : pale Sundew563. Dryandra polycephalus : many headed Dryandra564. Dryandra praemorsa : urchin Dryandra565. Dryas drummondii : yellow Dryas566. Dryas octopetala : Driade, Camedrio alpino567. Dryobalanops aromatica (Borneolo),568. Dryopteris filix-mas : Felce maschio (soggetta a restrinzioni legali in paesi)569. Dudleya cymosa : Canyon dudleya570. Ecballium elaterium : Cocomero asinino571. Echinacea purpurea, angustifolia, or pallida : Echinacea, Pianta Pettine, Rudbeckia rossa, pallida572. Echium vulgare : Erba viperina, Viperina azzurra, Serpentina, Erba rogna, Echio.573. Eclipta alba : Bhringaraj, Bhringaraj (English), Takasaburo (Japanese), Lichang (Chinese), Takasaburo (Japan)(Sanskrit)574. Eichornia crassipes : Giacinto d'Acqua575. Elephantopus scaber : Piede d'Elefante, Prickly leaves, Pied d'Elephant, Gojihiva (Sanskrit)576. Elettaria cardamomum : Cardamomo, Lessere cardamom, Cardamom (English), Kardamome (Deutsch),Cardamome (French), Karudemon (Japan), Ela Chhoti (Sanskrit);577. Eleuteria : Cascarilla578. Eleuterococcus senticosus (Acanthopanax senticosus) : Eleuterococco, Ginseng siberiano579. Elythranthera brunonis : purple enamel Orchid580. Embelia ribes, glandulifera : Embelia, Embelia Fruchte (Deutsch), Vidanga (Sanskrit)581. Emblica officinalis (Phyllanthus emblica) : Emblic myrobalan (English), Amla (German), Amara (Japan), AnMole (Chinese), Amalik (Sanskrit).582. Embotrium coccineum : Embotrio.583. Enothera biennis (Oenothera biennis) : Enotera, Rapunzia.584. Ephedra vulgaris : Efedra585. Epilobium angustifolium : Epilobio; Fireweed, white Fireweed; Epilobe (French)586. Epilobium latifolium : river Beauty587. Epilobium parviflorum : Epilobio; Epilobe, willow-Herb; Epilobe (French)588. Epimedium saggitatum : Yin Yang Huo589. Equisetum arvense : Coda di Cavallo, Coda cavallina, Setolone; Horsetail590. Equisetum hiemale : Asprella, Equiseto invernale.591. Equisetum maximum : Coda di Cavallo, Coda cavallina, Setolone; Horsetail592. Erica arborea : Scopa593. Erica vulgaris : Erica594. Erigeron alpinus : Cespola349

595. Erigeron canadensis : Erigero.596. Eriodictyon californicum : Erba santa; Yerba santa.597. Eriodictyon crassiflorium : Eriodicto.598. Eriophorum sp. : cotton Grass599. Eriophorum vaginatum : Erioforo600. Erithrea antaurium : Centaurea minore601. Erithronium purpurascens : Giglio di Daino; fawn Lily602. Eritichium nanum : Eritico603. Erodium cicutarium : Filarea604. Erodium moschatum : Erodio moscato, Erba muschio.605. Erthrina indica : indian Coral606. Eruca sativa : Rucola607. Ervum lens (Lens culinaris) : Lenticchie608. Eryngium campestre : Calcatreppolo609. Eryngium foetidum : thorny Coriander, Ci Yan Sui610. Erysimum officinale : Erisimo611. Erythraea centaurium : Centaurea minore612. Erythraea chilensis : Eritrea cilena613. Erythrina mulungu : Mulungu614. Erythrina variegatis orientalis : Corallo bianco; white Coral.615. Erythrina variegata, indica, stricta, corallodendron : Albero del Corallo indiano, indian Coral Tree, IndisherKorallen Baum (Deutsch), Arbre immorte (French), Deigo (Japanese), Paribhadra (Sanskrit).616. Erithronium dens-canis : Dente di Cane617. Erytroxylon coca : Coca618. Erythroxylum catuaba : Catuaba619. Eschscholtzia californica : Escolzia; california Poppy620. Eucalyptus caesia : silver princess Gum621. Eucalyptus erythrocorys : Illaria, Illyarrie622. Eucalyptus forresiana : fuchsia Gum623. Eucalyptus globulus : Eucalipto, Albero della Febbre624. Eugenia caryophyllata (or Caryophyllus aromaticus) : Garofano, Chiodi di Garofano (fiori), Eugenia aromatica;.Cloves(English)625. Eugenia jambolana (Syzygium jambolanum) : Jambul; black Berry, Gewarz Nelke, Pomme Rose, Natsume(Japanese), Tsao (Chinese), Jambu (Sanskrit)626. Euonymus europaeus : Fusaggine, Berretto da Prete, Corallini, Evonimo.627. Eupatorium cannabium : Canapa acquatica, Eupatoria628. Eupatorium perfoliatum : Canapa acquatica629. Eupatorium purpureum : Canapa acquatica rossa630. Eupatorium triplinerve, ayapana : Ayapana (Sanskrit)631. Euphorbia cyparissia : Erba cipressina632. Euphorbia hirta, or pilulifera : Euforbia; Pillenwolfsmilch (Deutsch), Dadakeeriya (Japanese), Dugadhika(Sanskrit);633. Euphorbia marginata : Euforbia marginata (Tossica634. Euphorbia milli : Christ's Thorn635. Euphorbia nerifolia : common Milk Hedge, Enpurge (French), Kirinkaku (Japanese), Snoohi (Sanskrit)636. Euphorbia peplus : Euforbia (Tossica)637. Euphorbia plentissima : pill-bearing Spurge638. Euphorbia pulcherrima : Stella di Natale (Tossica)639. Euphorbia resinifera : Euforbia640. Euphrasia alpina : Eufrasia641. Euphrasia officinalis : Eufrasia, Erba degli Occhi; Euphraise (French)642. Euspongia officinalis : Spugna di Mare643. Evodia rutaecarpa : Evodia644. Evonymus atropurpureus : Fusaggine nera645. Evonymus europaus : Fusaggine646. Evolvulus alsinoides : Vishnukraanti (Sanskrit)647. Fabiana imbricata : Pichi-Pichi648. Fagopyrum dibotrys : false Buckwheat, Ye Qiao Mai649. Fagopyrum esculentum : Grano saraceno, Grano nero; Buckwheat or black Wheat650. Fagus sylvatica : Faggio, Beech651. Ferula communis : Ferola, Ferolaggine, Finocchiaccio652. Ferula narthex (or scorodosma ) : Ferula o Assa fetida350

653. Ferula foetida : Assa fetida; Asafetida (Englisch), Perunkayam (Deutsch), Hingu (Sanskrit)654. Ficaria ranuncoloides : Ficaria655. Ficus benghalensis or indica : Banyan Tree, Figuier due bengal (French), Vata (Sanskrit)656. Ficus carica : Fico; Figuier (French) .657. Ficus racemosa, glomerata : country Fig Tree, Figuier du dialile; Attikka (Japanese), Udumbara (Sanskrit)658. Ficus religiosa : sacred Fig, Bobaum Peepal (Deutsch), Figuier-ou-arbe despagodes (French), Tenjikubodaiju(Japanese), Pou tichou (Chinese), Aswatha (Sanskrit).659. Ficus vesiculosus : alga bitorzoluta660. Filipendula ulmaria or Spiraea ulmaria [Rosaceae] : Olmaria, Ulmaria, Regina dei Prati .661. Flaveria contrayerba : Flaveria662. Foeniculum dulce : Finocchio dolce663. Foeniculum officinale : Finocchio664. Foeniculum sylvestre : Finocchio selvatico665. Foeniculum vulgare, or capillaceum (or Anethum foeniculum) [Umbrelliferae] : Finocchio selvatico, Anice dolce,Erba buona, Fennel, Garten Feuchel (Deutsch), Uikyo (Japanese), Hui Xiang, Hui-hsiang (Chinese), Satupuspa(Sanskrit).666. Fragaria vesca : Fragola selvatica667. Frangula alnus ( or Rhamnus frangula) : Frangola, Frangula668. Fraxinus excelsior : Frassino comune .669. Fraxinus ornus : Frassino orniello, Manna670. Fritillaria cirrhosa : Fritellaria; Crown671. Fritillaria imperialis : Fritellaria imperiale, imperial Crown672. Fuchsia hybrida, or macrostemma : Fucsia; Fuchsia673. Fucus vesiculosus : Alga bruna, Fucus, Quercia marina .674. Fumaria indica or parviflora : common Fumitory, Erdrauch (Deutsch), Tuysha Tu Chian (Chinese), Parpata(Sanskrit)675. Fumaria officinalis : Fumaria, Fumosterno, Fumitory676. Galanthus nivalis : Bucaneve677. Galega officinalis : Galega678. Galeopsis grandiflora : Galeopside679. Galipea officialis (or Cusparia febrifuga or officialis) : Angostura680. Galium mollugo : Caglio681. Galium verum : Gallio; Gaillet (French);682. Gallium aparina (Galium aparine) : Coglio, Aparine, Attaccamani, Attaccavesti683. Ganoderma lucidum : Fungo-Fantasma, Reishi684. Garcinia cambogia : Garcinia di Cambogia685. Garcinia indica, purpurea : Mango rosso, red Mango, Kokumol (Deutsch), Brikshamia (Sanskrit)686. Garcinia morella : Garcinia indiana; indian Gamboge, Gokatu (Deutsch), Tamal (Sanskrit)687. Gardenia jasminoides : Gardenia688. Gelsemium sempervirens : Gelsemio689. Genista hispanica :Aulaga, Argelago690. Gentiana acaulis or clusii : Genzianella, Genziana di Clusio691. Gentiana amarella : Genzianella autunnale, Gentian692. Gentiana asclepiadea : Genziana693. Gentiana germanica : Genziana autunnale694. Gentiana lutea : Genziana maggiore, Genziana gialla695. Gentiana rochiana : Genzianella696. Gentiana verna : Genzanella di Primavera697. Geocaulon lividum : Comandra698. Geranium erianthum : sticky Geranium699. Geranium robertianum : Geranio robertiano, Erba roberta, Erba cimicina, Cicuta rossa, Erba di Roberto;(potenzialmente tossica).700. Geranium silvaticum : Geranio selvatico701. Geum urbanum : Erba benedetta, Benedetta, Cariofillata di Monte, Ambretta702. Ghee : Burro chiarificato703. Ginkgo biloba : Ginkgo704. Gladiolus caryophyllaceus : pink Trumpet705. Gladiolus segetum : Spadacciola706. Glechoma hederaceum : Edera terrestre .707. Glicirida maculata : spotted Gliciridia708. Globularia cordifolia : Globularia strisciante709. Globularia vulgaris : Morine351

710. Gloriosa superba : superb Lily, Gloriosa Knollen (Deutsch), Glorieus du Malalier (French), Yurigurama(Japanese), Langalika (Sanskrit)711. Glycine maxima : soia gialla, yellow Soybean, soya Bean, Huang Dou712. Glycine soja : soia nera, black Soybean, Hei Dou713. Glycirrhiza glabra : Liquirizia, Radice dolce, Legno dolce; sweet Root; Sussholz (Deutsch), Kanzo (Japanese),Kan-ts'ao (Chinese), Yashtimadhu (Sanskrit) ;714. Gmelina arborea : Gambhari (Sanskrit)715. Gnaphalium polycephalum or gira-gira : Gnafalio, Verbasco716. Gnaphalium supinum : Zampa di Gatto717. Gonolobus condurango (Marasdenia cundurango): Condurango718. Gossypium herbaceum, indicum : indian Cotton, indische Baumwollenstaude (Deutsch), Cotoiner de-l'Inde, Wata(Japanese), Bong (Chinese), Karpas (Sanskrit).719. Gratiola officinalis : Graziola720. Grevillea bipinnatifida : fuchsia Grevillea721. Grevillea tenuiloba : golden Glory Grevillea722. Grewia hirsuta, polygama, pilosa : Gulsakri (Englisch), Nagbala (Sanskrit)723. Grifola frondosa : Fungo danzante; Maitake724. Grindelia robusta : Grindelia725. Guajacum officinale : Guaiaco726. Guarea rusbyi : Cocillana727. Guazuma ulmifolia : Mutamba728. Gymnema silvestre (Asclepias geminata) : Gimnema; Meshasringi (Sanskrit);729. Gynostemma pentaphyllum : Pianta dell’Immortalità730. Gynura bicolor : red back Vegetable, Hong Bei Cai (Chinese)731. Gypsophila repens : Velo da Sposa732. Hagenia abyssinica (or Brayera anthelmithica) : Braiera o Cusso733. Hakea laurina : pincushion Hakea734. Hamamelis virginiana : Amamelide, Nocciolo delle Streghe735. Hammarbya paludosa : green Fairy Orchid736. Harpagophytum procumbens : Arpagofito, Artiglio del Diavolo737. Hebe speciosa : Veronica738. Hedera helix : Edera comune, Ellera, Edera rampicante, Edera Helix739. Hedychium coronarium koenig : Butterfly Lily740. Hedysarum coronarium : Sulla741. Helianthemum nummularium : Eliantemo, Rosa di Roccia; Rock Rose; Heliantheme (French)742. Helianthus annuda : Sunflower743. Helianthus annuus : Girasole ; Sunflower (English)744. Helianthus tuberosus : Carciofo di Gerusalemme, Topinambur; Jeruralem Artichoke ;745. Helichrysum italicum : Elicriso italico .746. Helicteres isora : east indian Screw Tree, Caydotron (Chinese)747. Heliotropium angiospermum :Erba dell’Alacrano748. Heliotropium indicum (Cissus quadrangularis, Vitis quadrangularis) : Conciaossa; Bone setter, Hirassa,Asthisanhari (Sanskrit).749. Heliotropium peruvianum : Eliotropio peruviano.750. Helipterum roseum : pink everlasting Straw751. Helleborus niger : Elleboro nero (Tossica)752. Helleborus fetidus : Elleboro puzzolente (Tossica)753. Helleborus viridis : Erba Nocca(Tossica)754. Hemiandra pungens : Snakebush.755. Hemidesmus indicus : Sarsaparilla indiana, indian Sarsaparilla, Ostindische Sarsaparilla, Salsepareille indienne,Indosarusa (Japanese).756. Heracleum lanatum : Cow Parsnip757. Heracleum sphondylium : Panace, Ginseng italiano.758. Hibbertia scadens : Snakevine.759. Hibiscus abelmoschus o Abelmoscythus moschatus : Ambretta760. Hibiscus alba : Ibisco bianco; white Hibiscus761. Hibiscus abelmoschus (Abelmoschus moschatus) : musk Mallow, Lataksturikam (Sanskrit)762. Hibiscus sabdariffa : Ibisco, Carcadè; Hibiscus763. Hibiscus syriacus : Rose of Sharon, Mu Jin Hua764. Hieracium pilosella : Pilosella, Pelosella765. Hierochloe odorata : Sweetgrass766. Hinthostachys setosa :Muna-Muna352

767. Holarrhena antidysenterica : Kurchi Tree, Kurchirinde (Deutsch), Ecore-d'Codagapala (French), Konetsushi(Japanese), Kutaja (Sanskrit)768. Hordeum vulgare : Orzo; Barley769. Houttuynia cordata : Ottinia; cordate Houttuynia, stinking Fish Plant, Yu Xing Cao (Chinese)770. Hottonia palustris : Violetta d'acqua, Water violet771. Humulus lupulus : Luppolo, Cupola, Livertizio; Houblon (French);772. Hurtica dioica (or Urtica dioica) : Ortica grande; Ortie (French);773. Hybathhs calycinus : wild Violet774. Hydnocarpus laurifolia, wightiana : jangli Almond, Chaulmoogra (Deutsch), Daifushi (Japanese) Ta-feng-tzu(Chinese), Tuvaraka (Sanskrit).775. Hydrangea arborescens : Idrangea.776. Hydrastis canadensis : Idraste, Sigillo d'Oro, golden Seal777. Hydrocotile asiatica : Centella asiatica, indian Pennywort, Asiotischer Wassernabel, Tsubokura (Japanese),Mandukaparni (Sanskrit).778. Hygrophila auriculata (Asteracantha longifolia) : Langblathriger Sterndorn (Deutsch), Kokilaksha (Sanskrit).779. Hymenaea courbaril :Jatoba780. Hyoscyamus niger : Quisquiamo, Giusquiamo, Henbane, Bilsenkraut, Hiyosu (Japanese), Lao Lang Hoa (Chinese),Yavani (Sanskrit); (molto tossica)781. Hyoseris radiata : Ioseride782. Hypericum perforatum : Iperico, Pilatro, Cacciadiavoli, Erba di San Giovanni, Mille Buchi, Saint John's Wort783. Hypericum richeri : Iperico montano, Pilatro, Scacciadiavoli, Erba di San Giovanni784. Hypochaeris radicata : Piattello785. Hypoxis hemerocallidea : Patata africana786. Hippophae rhamnoides : Olivello spinoso787. Hyssopus officinalis : Issopo, Erba odorosa, Soleggio, Hyssop, Kleinblatt-Rigerysop, Yanagihakuga (Japanese),Zupha (Sanskrit);788. Kaempferia aethiopica : Kinkelibà789. Kaempferia galanga : sand Ginger, Galanga, Sha Jiang790. Kingia argentia : goddess Grasstree791. Krameria triandra : Ratania792. Iberis amara : Raspo amaro793. Ignatia amara (or Strychnos ignatii) : Fava di San Ignazio794. Ilex aquifolium : Agrifoglio, Holly795. Ilex paraguariensis : Matè796. Illicium verum : Anice stellato797. Impatiens glandulifera : Non Mi Toccare; Impatiens798. Inesinae calea : Aranto799. Inula helenium : Inula, Enula campana, Elenio, Erbella800. Ipomoea aquatica : water Spinach, hollow Vegetable, swamp Cabbage, Weng Cai801. Ipomoea batatas : Batata rossa, Patata americana, Batata, sweet Potato, Hong Shu802. Ipomoea nil, hederacea, pharbitis : pharbitis Seeds, Kaladana Harz (Deutsch), Krishnavijani803. Ipomoea purpurea : Gloria del Mattino; morning Glory; Ipomee .804. Ipomoea turpethum (Operculina turpethum; Convolvulus turpethum) : indian Jalap; Brast Liauische; Trivrit(Sanskrit).805. Iris douglasiana : Iride, Giaggiolo; Iris.806. Iris florentina : Iride bianco, Giaggiolo bianco; white Iris807. Iris germanica : Iride, Ireos, Giaggiolo808. Iris pseudo-acorus : Iride giallo, Giaggiolo giallo, Coltellaccio; yellow Iris809. Iris setosa : wild Iris810. Iris versicolor : Iride multicolore, Iride comune, Giaggiolo comune811. Ixeris denticulata : chinese vegetable, Bitter, Ku Mai Cai (Chinese)812. Ixora : Ixora813. Isopogon formosus : rose Cone814. Jasmine officinalis : Jasmin (French).815. Jasmine arborescens : night Jasmine816. Jasminum sambac : arabian Jasmine, Arabischer Jasmin, Matsurika (Japanese), Moli (Chinese), Mallika (Sanskrit).817. Jateorrhiza columba : Colombo818. Jatropa manihot (or Manihot utilissima) : Manioca amara819. Junglans nigra : Noce nero820. Junglans regia : Noce comune, Walnut, Nut Tree;821. Juniperus communis : Ginepro, Petron, Juniper Berry; Wacholder Beere (Deutsch), Baie de genevrier, Hapusa(Sanskrit);353

822. Juniperus sabina, zelanica) : Malabar Nut; Malabar Nuss; Adotada (Japanese); Vasaka (Sanskrit).823. Laburnum anagyroides : Laburno, Maggiociondolo; Laburnum; (tossica)824. Lactuca sativa : Lattuga, Celtuce, Lettuce, asparagus Lettuce , Wo Ju825. Lactuga sativa capitata : Lattuga a cappuccio826. Lactuga scariola : Lattuga scariola827. Lactuga virosa : Cavolaccio828. Lagenaria sinceraria : Calabash, bottle Gourd, Hu Lu (Chinese)829. Laminaria digitata : Laminaria; Kelp830. Lamium album : Lamio, Ortica bianca, Milzadella.831. Lamium purpureum : Lamio rosso832. Lapsana communis : Lassana, Erba delle Mammelle833. Larix decidua : Larice834. Larix europaea : Trementina835. Larix laricina : Tamarack836. Larrea mexicana : Chaparral837. Larrea nitida : Larrea838. Lathyrus latifolius, odoratus : Pisello odoroso, sweet Pea (English)839. Laurus camphora, Dryobalanops aromatica : Lauro della Canfora840. Laurus nobilis : Alloro841. Lavandula officinalis, angustifolia, spica : Lavanda, Spigo, Nardo, Spigonardo.842. Lavandula stoechas : Steca o Sticadosso843. Lawsonia inermis : Hennè .844. Lens culinaris (Ervum lens) : Lenticchie.; Lentils845. Lentinus edodes : Shitake846. Ledum palustre : Rosmarino selvatico, Ramerino di Palude, The del Labrador; Labrador Tea847. Leontodon taraxacum (Taraxacum officinalis) : Tarassaco, Dente di Leone, Cicoria matta, Soffione848. Leontodon tuberosus : Leontodo849. Leonurus cardiaca : Cardiaca850. Lepidium meyenii : Maca-Maca851. Lepidium sativum : Agretto, Crescione inglese, Crescione comune852. Leschenaultia biloba : blue Leschenaultia853. Lechenaultia formosus : yellow, red, orange Leschenaultia.854. Leontopodium alpinum : Stella alpina855. Lepidium latifolium : Mostardina856. Lepidium sativum : Agretto, Cardamomo857. Leptandra virginiana : Leptandra858. Lespedeza capitata : Lespedeza859. Leucanthemopsis alpina : Crisantemo delle Alpi860. Leucojum aestivum : Campanelle861. Leucojum vernum : Campanellino o Bucaneve maggiore862. Levisticum officinale (Meum mutellina) : Levistico, Sedano di Montagna863. Libertia coerulescens : Libertia864. Lichen islandicus : Lichene islandico865. Ligustrum lucidum or vulgare : Ligustro866. Lilium candidum : Giglio867. Lilium humboldtii : Giglio della Tigre; Tiger Lily868. Lilium longiflorium : Giglio dell'Est; eastern Lily869. Lilium martagon : Lis martagon (French);870. Lilium parvum: Giglio alpino; alpine Lily871. Linaria alpina : Linaria di Monte872. Linaria vulgaris : Linaria, Linaiola873. Linnanea borealis : Twinflower874. Linum catharticum : Lino catartico875. Linum usitatissimum : Lino, Linosa; Linseed (English); Flachs (Deutsch); Lin (French); Ana (Japanese); Hou matse (Chinese); Uma (Sanskrit).876. Lippia citridora : Verbena odorosa, Erba eloisia, Erba Luigia877. Liriosma ovata or Ptychopetalum olacoides : Muira Puama .878. Listera borealis : northern Twayblade879. Listera cordata : Tundra Twayblade880. Lithospermum officinale : Migliarino .881. Litsea glutinosa, chinensis, sebifera : Maidasak (Sanskrit)882. Lobelia inflata : Lobelia .354

883. Lobelia nicotianaefolia : Lobelic (Deutsch); Nala (Sanskrit)884. Loiselluria procumbes : Azalea alpina; alpine azalea885. Lolium temulentum : Loglio886. Lonicera caprifolium : Madreselva, Caprifoglio, Honeysuckle.887. Lophophytum leandri : Fiore di Pietra888. Lotus alpina : Ginestrino di Monte889. Lotus corniculatus : Ginestrina, Ginestrino; five-finger (english)890. Luffa acutangula : Ribbed gourd; Scharfeckige Gurke (Deutsch); Pipangua (French); Tokadochechima (Japanese);Szukua (Chinese); Koshataki (Sanskrit)891. Luffa aegyptiaca, or operculata : Luffa; sponge Gourd; Luffa Schwammlobelic (Deutsch); Mechima (Japanese);Szu skua (Chinese); Dhamargava (Sanskrit).892. Luffa cylindrica : Towel Gaourd, silk Melon, Loofah, Si Gua (Chinese)893. Lupinus albus : Lupino ;Lupin(english)894. Lychnis alba : Licnide bianca895. Lychnis flos-cuculi : Fior di Cuculo896. Lychnis rubra : Licnide rosa897. Lycium chinense : chinese Wolfberry, Gou Qi Cai, or Cou Qi Zhi (Chinese)898. Lycium europaeum : Spinacristi; Wolfberry (Tossica)899. Lycopersicum esculentum : Tomato, Fan Qie900. Lycopodium clavatum : Licopodio901. Lygustrum vulgare : Ligustro902. Lypercanthus nigricans : red beak Orchid903. Lythrum salicaria : Salicaria, Salcerella904. Macropidia fuliginosa : black Kangaroo Paw905. Macrozamia reidlei : Macrozamia906. Madia elegans : Madia907. Madia sativa : Melosa908. Madhuca longifolia (Bassia longifolia) : indian Butter Tree; Madhuka (Sanskrit)909. Majorana hortensis (Oreganum majorana : Maggiorana; Marjoram(English)910. Mallotus philippensis (Croton philippensis) : Rottlera (English); Kamala (Deutsch); Kamola (French); Kampillaka(Sanskrit)911. Malpighia punicifolia or glabra : Acerola912. Malus communis (or Pirus malus) : Mela; Apple ; Pommier (French);913. Malus sylvestris : Melo ornamentale; crab Apple ;914. Malva crispa : cluster Mallow, Dong Jui (Chinese)915. Malva silvestris, vulgaris, nelecta : Malva916. Mandragora officinarum : Mandragora (potenzialmente tossica)917. Manihot utilissima (or Jatropa manihot) : Manioca amara918. Marasdenia cundurango (Gonolobus condurango) : Condurango919. Mardenbergia comptoniana : happy Wanderer920. Margycarpus setosus : Margicarpo921. Marrubium vulgaris : Marrobio bianco, Marrubio bianco, Erba arpiola922. Matricaria chamomilla : Camomilla comune, Camomilla vera, Camomilla volgare923. Matricaria inodorosa : Camomilla bastarda924. Matricaria matricaroides : pineapple Weed925. Matricaria parthenum : Matricaria, Amoreggiola926. Maytenus illicifolia : Espineira santa927. Maytenus krukovit :Chuchuhuasi928. Medicago sativa : Erba medica, Alfa Alfa ;Lucerne(english)929. Megastigma lutea : yellow Boronia930. Melaleuca alternifoglia : Albero del TheMelaleuca leucodendron or minor (Cajeput),Melaleuca quinquenervia viridiflora (Niaouli),931. Melaleuca thymafolia : mauve Melaleuca932. Melia azadirachta, azedarach : persian Lilac; Gemeiner Zedrach; Margosier; Nimba (Sanskrit).933. Melilotus officinalis : Meliloto, Erba vetturina ; yellow melilot(english)934. Melissa monarda, officinalis, calamintha : Melissa, Citronella, Cedronella, Erba bergamotta, Erba Limone; balm-Mint (English).935. Melittis melissiphyllum : Melitta936. Mentha arvensis : Corn mint; Mint (English); Minze (Deutsch); Midorihakka (Japanese); Puthea (Sanskrit).937. Mentha haplocalyx : Peppermint, Bo He938. Mentha piperita, viridis : Menta; Peppermint .355

939. Mentha pulegium : Menthe pouliot (French)940. Mentha spicata : Spearmint, Liu Lan Xiang941. Menyanthes trifoliata : Trifoglio d'Acqua, o Trifoglio fibrino942. Mercurialis annua : Mercorella943. Merremia hederacea : morning Glory, Pa Li Cai (Chinese)944. Mertensia paniculata : chiming Bells945. Mesembryantheum chilense : Mesembriantemo946. Mespylus germanica : Nespola comune947. Mesua ferrea : Croco di Cobra; Cobra's Saffron; Nagassamen (Deutsch);Tagayasan (Japanese); Thiet lucmoc(Chinese); Nagkeshara (Sanskrit).948. Meum athamanticum : Finocchiella949. Meum mutellina (Levisticum officinale) : Levistico, o Sedano di Monte950. Michelia champaca : yellow Champa; Wohlrieshen-de Michele (Deutsch); Champac (French); Kinkoboku(Japanese); Champaka (Sanskrit).951. Milium effusum : Miglio; Millet(English)952. Mimosa cavenia : Mimosa953. Mimosa tenuiflora : Mimosa, Albero della Pelle; Tepezcohuite954. Mimulus aurantiacus : sticky Monkey955. Mimulus cardinalis : scarlet Monkey956. Mimulus guttatus : Mimolo giallo; Mimulus957. Mimulus lewisii : pink Monkey958. Mimusops elengi : Affengesict (Deutsch); Karanicim (French); Bakula (Sanskrit).959. Mirabilis jalapa : Bella di Notte960. Moehringia lateriflora : grove Sandwort961. Molucella laevis : green Bells of Ireland962. Momordica balsamica : Mela balsamica963. Momordica charantica : Cocomero d'Africa, Balsam-Pear, bitter Melon, Ku Gua964. Monardella odoratissima : mountain Pennyroyal ;965. Moneses uniflora : single Delight966. Morinda citrifolia : Bumbo africano, Gelso indiano, Gran Morinda, Lada, Mengkudo, Nhau, Nonu, Noni, Nono).967. Moringa oleifera, pterygosperma : Moringa; Horseradish Tree, Drumstick; Moronguier; Sigru (Sanskrit).968. Morus alba : gelso bianco, indian Mulberry969. Morus celsa : Gelso970. Morus nigra : Gelso nero971. Mucuna pruriens : Cow-itch Plant; Jackbohne (Deutsch); Hatsushomame (Japanese); Kapikachchha (Sanskrit).972. Muehenbeckia volcanica or Physalis angulata:Mullaca973. Multifida dilitata : Brachyome974. Murdannia braceata : spit fire Vegetable, Tan Huo Cai975. Murraia Koelgu Spreng : Curry Leaf976. Musa sapientum, acuminata, paradisiaca : Banana, Platanos (Espagnol).977. Muscari botryoides : Pentolini, Muschini.978. Muscari camosus : Cipollaccio979. Myosotis sylvatica or alpestris : Forget-me-Not980. Myrcia salicifolia : Pedra Hume Caa981. Myrciaria paraensis or dubia : Camu-Camu, Kamu-Kamu982. Myrica gale : Sweetgale983. Myrica salicifolia :Pedra Hume Caa.984. Myristica fragrans, sebifera : Noce moscata, Miristica odorosa; Nutmeg (English) Echtermuscatnussbaum(Deutsch); Nikuzuku (Japanese); Jatiphalam (Sanskrit).985. Myroxylon balsamum or pereirae : Tolù, Balsamo di Tolù986. Myrrhis odorata : Mirra odorata, Miride, Finocchiella987. Myrtus communis : Mirto, Mortella, Pepe della Corsica988. Narcissus poeticus : Fior Maggio, Narciso silvestre989. Narcissus pseudonarcissus : Narciso silvestre, Trombone, Giunchiglia, Tazzinella990. Narcissus tazzetta : Tazzetta991. Nardostachys jatamansi : Nardo indiano; Musk root (English); Indische Narde; Jata-manchi (French); Kan Sung(Chinese); Jatamansi (Sanskrit).992. Nasturtium officinale : Nasturzio, Crescione, Watercress, Xi Yang Cai993. Nelumbium nelumbo, speciosum (Nelumbo nucifera, Nymphaea nelumbo) : Loto sacro, Loto indiano; sacred Lotus,lotus Root, Indische Lotosblume; Lotus sacre; Hasu (Japanese); Lienou , Ou (Chinese); Kamal (Sanskrit).994. Nemophila menziesii : Occhi Blu di Bambino; Baby Blue Eyes995. Nepeta cataria : Erba gatta, Cataria, Erba gattaia, Nepitella, Menta dei Gatti, Menta selvatica356

996. Nerium indicum, odorum : Roseberry Spurge; Wahlriechender Oleandes (Deutsch); Kenera (Japanese); Kyochikuto(Chinese); Karavira (Sanskrit).997. Nerium oleander : Oleandro (Tossica)998. Nicotiana alata : Nicotiana, Fiore del Tabacco; Tobacco999. Nicotiana tabacum : Tabacco (potenzialmente tossica)1000. Nigella damascaena : Damigella o Fanciullaccia (Tossica)1001. Nigella sativa (Carum nigrum) : Melanzio nero, Cumino nero; black Cumin; Schwarzkummel; Cumin noir;Nigera (Japanese); Upakunchika (Sanskrit);1002. Nuytsia floribunda : Cristo dell'Australia; west australian Christmas Tree.1003. Nux moschata : Noce moscata1004. Nymphaea alba : Ninfea, Carfano; water Lily.1005. Nymphaea nelumbo (Nelumbium nelumbo, speciosum; Nelumbo nucifera) : Loto sacro, Loto indiano; sacredLotus, Indische Lotosblume; Lotus sacre; Hasu (Japanese); Lienou (Chinese); Kamal (Sanskrit).1006. Nymphaea violacea : purple nymph Waterlily1007. Nyctanthes arbor-tristis : Night Jasmine; Parijata (Sanskrit)1008. Ochrocarpus longifolius : Alexandrian Laurel; Punnaga (Sanskrit).1009. Ocimum basilicum : Basilico dolce, Erba reale, Arancio dei Ciabattini; sweet Basil, Basil (English); Basilic(Frenc); Luo Le (Chinese).1010. Ocimum sanctum : Basilico odoroso; Holy Basil; Basttikum (Deutsch); Basilic odorant; Tulssi (Sanskrit).1011. Oenanthe aquatica : Finocchio acquatico (tossico)1012. Oenanthe crocata : Enante (molto tossica)1013. Oenanthe javanica : water Celery, water Dropwort, Shui Qin1014. Oenanthe phellandrium : Fellandrio o Finocchio acquatico (molto tossica)1015. Oenothera acaulis : Enotera1016. Oenothera biennis (Enotera biennis) : Enotera1017. Oenothera hookery : Primavera della Sera; evening Primrose1018. Oenothera multicaulis :Saya-Saya1019. Olea europaea : Olivo; Olive1020. Oninis repens : Bulinaca (potenzialmente tossica)1021. Ononis spinosa (or Adonis vernalis ) : Anonide, Ononide, Ononide spinosa (potenzialmente tossica)1022. Operculina turpethum (Ipomoea turpethum; Convolvulus turpethum) : indian Jalap; Brast Liauische; Trivrit(Sanskrit)1023. Ophrys apifera : Vesparia1024. Orchis maculata : Concordia1025. Orchis morio : Giglio caprino, Pan di Cuculo1026. Origanum dictamnus : Dittamo1027. Origanum majorana (Majorana hortensis) : Maggiorana; Marjoram(English)1028. Origanum vulgare : Origano, Menta bastarda, Erba acciuga, Maggiorana selvatica; Oregano(English)1029. Ornithogalum umbellatum (or Calectasia) : Latte di Gallina, Cipollone bianco, Stella di Betlemme, Star ofBethlehem.1030. Oroxylum indicum : Ch'len Tseng (Chinese); Shyonaka (Sanskrit)1031. Orthosiphon stamineus : Ortosifon, The di Giava1032. Oryza sativa : Riso; Rice (English)1033. Oxalis acetosella : Acetosella1034. Paederia foetida : Pianta del Fiore cinese; chinese Flower Plant; Prasarini (Sanskrit).1035. Paeonia officinalis : Peonia1036. Papaver rhoeas : Papavero rosso, Rosalaccio1037. Papaver somniferum : Oppio; Papevero del Sonno, Papavero sonnifero1038. Paris quadrifolia : Uva di Volpe (potenzialmente tossica)1039. Passiflora incarnata or edulis : Passiflora, Maracuja1040. Passiflora mollissima : Curuba1041. Pastinaca sativa : Pastinaca; parsnips(english)1042. Patersomia occidentalis : purple Flag1043. Panax ginseng : Ginseng coreano, Radice della Vita, Radice d'Uomo1044. Panax quinquefolium : Ginseng americano1045. Pandanus odoratissimus, tectorius : Fragrant Screwpine; Schrauben Palme; Togenashiadan (Japanese); Kataki(Sanskrit).1046. Panicum miliaceum : Miglio1047. Papaver icelandica : Papavero islandese, icelandic Poppy1048. Papaver rhoeas : Rosalaccio (potenzialmente tossico)1049. Papaver somniferum : Papavero dell' Oppio; Opium Poppy; Mohn (Deutsch); Keshi (Japanese); Ya-pin(Chinese); Affiun; Ahiphenam (Sanskrit).357

1050. Parietaria officinalis : Parietaria1051. Parnassia palustris : Erba di Parnasso; Grass of Parnassus1052. Passiflora edulis or incarnata :Passiflora, Maracuja, Passiflore (French)1053. Pastinaca sativa : Pastinaca1054. Patersonia xanthina : yellow Flag1055. Pachyrhizus erosus : Yam Beam, Liang Shu1056. Paullinia sorbilis or cupana : Guaranà1057. Paw anigozanthos manglesii : yellow and green Kankgaroo1058. Pedicularis rostrato-capitata : Pedicolare1059. Peganum harmala : syrian Rue; Harmelraute; Harmal (Sanskrit)1060. Pelargonium graveolens : Geranio1061. Penstemon davidsonii : Penstemon1062. Penstemon newberry : mountain Pride1063. Perilla frutescens : Perilla; purple Perilla, Zi Su (Chinese)1064. Persea amaericana : Avocado1065. Persea gratissima : Pero avocato1066. Petasites hybridus, officinalis : Petasite, Farfaraccio, Cavolaccio1067. Petrophile linearis : pixie Mops1068. Petroselinum crispum or sativum : Prezzemolo riccio1069. Petroselinum hortense (or Apium petroselinum or Carum petrioselinum) : Prezzemolo1070. Peucedanum graveolens (Anethum sowa) : indian Dill (English); garten Dill; Indndo (Japanese); MisroyaSatapushpi (Sanskrit).1071. Peucedanum officinale : Finocchio porcino1072. Peucedanum ostruthium : Erba rena, Imperatoria.1073. Peumus boldus : Boldo1074. Pfaffia paniculata : Suma1075. Phaseolus vulgaris : Fagiolo ; Beans(English).1076. Phellodendron pertusum (or Philodendron pertusum) : Filodendro o Monstera.1077. Phitolacca decandra : Fitolacca.1078. Phoenix dactylifera : Dattero1079. Phyllanthus emblica (Emblica officinalis) : Emblic myrobalan (English), Amla (German), Amara (Japan), AnMole (Chinese), Amalik (Sanskrit)1080. Phyllantus fraternus, niruri : Spaccapietra, Chanca Pietra (Espagnol) Niruri (French); Kidachimikanso(Japanese); Bhumyaamlaki (Sanskrit).1081. Phyrus communis : Pera; Pear1082. Physalis alkekengi : Alkekengi, Alchechengio, Chichingero.1083. Physalis angulata or Muehenbeckia volcanica :Mullaca1084. Phyteuma hemisphaericum : Fiteuma1085. Phyteuma spicatum : Fiteuma spigata1086. Phytolaccia decandra : Fitolaccia1087. Picca mariana : black Spruce1088. Picea sitchensis : sitka spruce Pollen1089. Picrorrhiza kurroa : Kooren (Japanese); Hu Huang Line (Chinese); Katula (Sanskrit).1090. Picea abies : Epicea (French)1091. Picea excelsa (or Abies excelsa) : Abete rosso1092. Picea glauca : white Spruce1093. Picea marina (or Pinus maritima) : Pino marittimo1094. Pieris echioides : Aspraggine1095. Pilea cavalieriei : stone oil Rape, Shi You Cai (Chinese)1096. Pilocarpus jaborandi : Jaborandi1097. Pimenta racemosa (Pimento),1098. Pimpinella anisum : Anice, Anice verde, Aice comune, Cumino dolce; Anise(English)1099. Pimpinella magna : Tragoselino1100. Pimpinella major : Pimpinella, Tragosellino1101. Pimpinella saxifraga : Pimpinella1102. Pinguicula villosa : hairy Butterwort1103. Pinguicula vulgaris : Pinguicola1104. Pinus deodara (Cedrus libani, deodora) : Cedro del Libano, Deodar, Cedre deodar (Sanskrit)1105. Pinus maritima (or Picea maritima) : Pino marittimo1106. Pinus mughus, pumilius : Pino mugo, Mugo1107. Pinus pinea :Pino;Pine(English)1108. Pinus sylvestris : Pino silvestre, Pino della Scozia; Pine (English)358

1109. Piper angustifolium : Matico1110. Piper longum : Pepe lungo; Long Pepper; Racines de poivre long; Hihatsu (Japanese); Pipo (Chinese); Pipali(Sanskrit).1111. Piper methysticum : Kava Kava, Pepe kawa1112. Piper nigrum : Pepe nero; black Pepper; Schwartzer Pfeffer; Poivre noir; Hu Jiao, Huchio (Chinese); Maricha(Sanskrit).1113. Piper sarmentosum : false Pepper, Jia Ju (Chinese)1114. Pirola rutundifolia : Limonio1115. Pirus malus (or Malus communis ) : Mela; Apple; Pommier (French);1116. Piscidia erythrina : Piscidia1117. Pistacia lentiscus : Lentisco, Lentischio.1118. Pistacia vera : Pistacchio;Pistachios1119. Pisum sativum : Piselli, Pea, (English) Wan Dou (Chinese)1120. Pittosporum tobira : Pitosporo1121. Platanthera obtusta : green Bog Orchid1122. Plantago arenaria : Psillio1123. Plantago coronopus : Coronopo1124. Plantago lanceolata : Piantaggine femmina1125. Plantago major : Piantaggine maggiore, Pentacciola pelosa; Ripplegrass, Waybread, Plantain, Che Qian Cao(Chinese).1126. Plantago ovata : Ispaghul, Psillo indiano; Spogel Seeds, Ispaghula; Indische Psylli-samen (Deutsch); Obeko(Japanese); Ch'-Ch'ientzu (Chinese); Ashwagolam (Sanskrit).1127. Plantago psyllium : Psillio1128. Platanus orientalis : Platano1129. Plygonum bistorta : Bistorta1130. Plumbago zeylanica : white Leadwort; Bleiwurz; Dentalaire de Cylon; Indo matsuri (Japanese); Pai Hau(Chinese); Chitraka (Sanskrit).1131. Plumeria alba : Fiore della Pagoda, Fiore del Tempio, Pagoda Flower.1132. Plumeria rubra : Temple1133. Phoenix dactylifera : Datteri1134. Poinciana pulcherrima : Peacock1135. Polemonium pulcherrima : Jacob's Ladder1136. Polygala amara : Poligala amara1137. Polygala chinensis : Poligala cinese1138. Polygala senega or virginiana : Poligala senega, Poligala della Virginia1139. Polygonum alaskanum : wild Rhubarb1140. Polygonum aviculare : Coreggiola, Correggiola, Centinodia, Sanguinaria1141. Polygonum bistorta : Bistorta, Serpentina1142. Polygonum hydropiper : Pepe d'Acqua1143. Polygonatum officinale (or Convallaria polygonatum) : Poligonato, Sigillo di Salomone1144. Polypodium lepidopteris : Samambaia1145. Polypodium vulgare : Felce dolce, Polipodio1146. Polyporus officinalis : Agarico bianco1147. Polysticum filix-mas : Felce maschio1148. Populus balsamifera : balsam Poplar1149. Populus nigra : Pioppo nero1150. Populus tremula, tremuloides : Pioppo tremulo; Aspen;1151. Portulara grandiflora : office Flower1152. Portulaca oleacea : Portulaca, Porcellana, Purslane, Ma Chi Xian (Chinese)1153. Potentilla anserina : Anserina, Argentina1154. Potentilla aurea : Pontentilla dorata1155. Potentilla erecta : Tormentilla1156. Potentilla fruticosa : Rosa della Tundra; Tundra Rose1157. Potentilla grandiflora : Tormentilla1158. Potentilla reptans : Cinquefoglio1159. Potentilla tormentilla : Tormentilla.1160. Poterium sanguisorba : Meloncello, Salvastrella1161. Poterium spinosum : Spinaporci1162. Premna corymbosa, integrifolia, obtusifolia (Cornutia corymbosa): Corimbosa; Agnimantha (Sanskrit)1163. Primula acaulis : Primavera ad Occhio di Civetta1164. Primula hirsuta : Primula irsuta, o viscosa1165. Primula officinalis, veris : Primula, Primavera359

1166. Prosopis pallida :Algarroba1167. Prunella vulgaris : Brunella; self-Heal ; Brunelle1168. Prunus africana : Pygeum africano1169. Prunus amygdalus (or Amygdalus communis) : Mandorla, Mandorle, Mandorle dolci; Almond; Mandelbaum;Amandier; Badama (Sanskrit).1170. Prunus armeniaca : Albicocca, Apricot (French)1171. Prunus avium : Ciliegia selvatica1172. Prunus cerasifera : Mirabolano; Cherry Plum1173. Prunus cerasus : Ciliegia, Amarasco, Ciliegia visciola, Marasca-Cherry1174. Prunus domestica : Susino, Pruno domestico1175. Prunus laurocerasus : Lauroceraso (potenzialmente tossica)1176. Prunus mumus : Pruno cinese1177. Prunus nigra : Prugna nera1178. Prunus persica : Pesca; Pecher (French).1179. Prunus puddum : bird-cherry (English); Traubenkirsche; Padmaka (Sanskrit).1180. Prunus spinosa : Prugna selvatica, Prugnolo1181. Prunus subhirtella : Ciliegio del Giappone1182. Psidium guajava :Guava1183. Psoralea corylifolia : Babchi Seeds; Bawchan (Deutsch); Vakuchi (Sanskrit).1184. Pteleopsis habeensis : Emba-Tule1185. Pterocarpus marsupium : Malabarkino (English and Deutsch); Pterocarp (French); Pitasala (Sanskrit).1186. Pterocarpus santalinus : red Sandalwood; Dunkelrothe Flugel- Fruct; Santal rouge (French); Tan hasiang(Chinese); Rakta chandana (Sanskrit)1187. Ptychopetalum olacoides or Liriosma ovata : Muira puama1188. Pulmonaria angustifolia : Polmonaria a Foglie strette1189. Pulmonaria officinalis : Polmonaria1190. Pulsatilla nigricas (or Anemone pulsatilla) : Anemone dei Prati1191. Pulsatilla vulgaris : Pulsatilla1192. Punica granatum : Melograno; Pomegranate; Granatbaum; Grenadier; Zakuro (Japanese); An-shih-liu(Chinese); Dadima (Sanskrit).1193. Ptychotis ajowan (Carum copticum, Trachyspermum ammi) : Aiovano; Omum, Ajowan Kummel, Yamani2) Pueraria thomsonii : sweet kudzu Vine, Gan Ge (Chinese)1194. Pulicaria dysenterica : Pulicaria1195. Pyrethrum coronarium : Piretro1196. Pyrethrum partenium : Erba di Santa Maria1197. Pyrola secunda : one-sided Witergreen1198. Pyrus cydonia : pera cotogna1199. Pyrus sorbus : Sorbo1200. Quassia amara or excelsa : Quassia1201. Quercus alba : Quercia bianca1202. Quercus peduncolata : Farnia, Eschio1203. Quercus robur : Quercia comune, Rovere; Oak1204. Quillaia saponaria or smeghaderina : Quillaia1205. Quisqualis indica : ragoon Creeper1206. Ranunculus acris, acer : Ranuncolo, Bottone d'Oro; Bouton d'Or (potenzialmente tossica)1207. Ranunculus bulbosus : Lappio1208. Ranunculus ficaria : Favagello o Celidonia minore1209. Ranunculus glacialis : Erba camozzera1210. Ranunculus occidentalis : Ranuncolo di Palude, Buttercup1211. Raphanus sativus niger : Rafano nero, Ravanello nero, Radice nera1212. Raphanus sativus : Ramolaccio; Radish; Riibenrettig (Deutsch); Raifort cultivé; Daikon (Japanese); Lai fu(Chinese), Luo Bo (Chinese); Moolaka (Sanskrit).1213. Raphanus sativus parvus : Ravanello1214. Rauwolfia serpentina : Serpentina (Italian and English); Rauwalfia (Deutsch); Indojaboku (Japanese);Sarpagandha (Sanskrit); .1215. Reseda odorata : Reseda1216. Rhamnus cathartica : Spino cervino .1217. Rhamnus frangula or Frangula alnus : Frangola, Frangula .1218. Rhamnus sagrada or purshiana : Cascara, Sagrada, Cascara sagrada.1219. Rheum emodi : Rabarbaro indiano; indian Rhubarb; Chosendaio (Japanese); Yunn-anta-huang (Chinese);Amlavetasa (Sanskrit).1220. Rheum officinale : Rabarbaro; Rhubarb; Rhabarber; Rhubrabde360

1221. Rheum sinense or palmatum : Rabarbaro cinese; chinese Rhubarb;1222. Rhodiola rosea : Radice d'Oro, o Radice artica1223. Rhododendron campylocarpum, aureum, chrysanthum : Rododendro, Rosa alpina1224. Rhododendron ferrugineum : Rhododendron (French).1225. Rhus aromatica : Rhus aromatica1226. Rhus cotinus : Cotino (Tossica)1227. Rhus diversiloba : poison Oak1228. Rhus succedanea : Sommacco; Galls; Sumach (Deutsch); Hazenoki (Japanese); Lu (Chinese); Karkatashringi(Sanskrit)1229. Ribes nigrum : Ribes nero1230. Ribes rubrum : Ribes rosso1231. Ricinus communis : Ricino comune; Castor oil Plant; Rhizinus (Deutsch); Ricin (French); Togoma (Japanese);Peima (Chinese); Eranda (Sanskrit).1232. Robinia pseudo acacia : Falsa Acacia, Robinia; false Acacia, locust Tree1233. Rorippa indica : indian Fieldcress, Hang Cai1234. Rosa acicularis : prickly wild Rose1235. Rosa californica : Rosa californiana, california wild Rose1236. Rosa canina : Rosa canina, Rosa selvatica, Rosa spina, Rosa di Macchia, Scarnigia, Sweet brier, Wild Rose; .1237. Rosa centifolia : Rosa pallida1238. Rosa gallica or damascena : Rosa rossa1239. Rosa moschata : Rosa muschiata1240. Rosmarinus officinalis : Erba da Corone, Erba dei Trovatori, Ramerino, Tresomarino; Rosemary; Rosmarin(French); .1241. Rottlera tinctoria or Mallotus philippinensis : Rottlera1242. Rubia cordifolia : indian Madder; Farberwurzel (Deutsch); Garance (French); Akane (Japanese); Ch'ien-ts'oa(Chinese); Manjista (Sanskrit).1243. Rubia tinctorium : Robbia1244. Rubus fruticosus, orsinus : Mora, Rovo; Blackberry; Mure sauvage1245. Rubus idaeus : Lampone1246. Rudbeckia hirta : black-eyed Susan1247. Rumex acetosa : Acetosa1248. Rumex crispus : Romice comune, Lapazio1249. Rumex patentia : Lapazio1250. Ruscus aculeatus : Rusco, Pungitopo, Asparago pazzo1251. Ruta graveolens : Ruta; Garden Rue; Raute (Deutsch); Matskareso (Japanese); T'sao (Chinese); Sadapaha(Sanskrit); (potenzialmente tossica)1252. Saccharomyces cerevisiae : Lievito di Birra1253. Sagittaria trifolia : Arrowhead , Ci Gu1254. Salix alba : Salice bianco1255. Salix bebbiana : Willow1256. Salix purpurea : Salice rosso1257. Salix vitellina : Salice giallo; Willow1258. Salmalia malbarica : red silk Cotton1259. Salvadora persica : Salvatore di Persia; Tooth brush Tree; Perische (Deutsch); Salvadore de Persa; Pilu(Sanskrit).1260. Salvia lavandulifolia, officinalis : Salvia, Erba gobba, Erba sacra; Sage (English); Sauge (French);1261. Salvia militiorrhiza : Salvia cinese1262. Salvia pratensis : Salvia dei Prati1263. Salvia sclarea : Salvia slarea .1264. Sambucus ebulus : Ebbio1265. Sambucus nigra : Sambuco, Sambucaro, Sango .1266. Sanguinaria canadensis : Sanguinaria .1267. Sanguisorba officinalis or Poterium sanguisorba : Sanguisorba, Pimpinella, Salvastrella;1268. Sanguisorba stipulata : sitka Burnet1269. Sanicula europaea : Erba fragolina1270. Santalum album : Sandalo; white Sandalwood; Weisses Sandelholz (Deutsch); Santal (French); Byakudan(Japanese); Tan hsiang (Chinese); Chandanam (Sanskrit).1271. Santolina chamaecyparissus : Santolina1272. Santureja hortensis : Peverella Satureia, Santoreggia1273. Santureja montana : Santoreggia montana1274. Saponaria officinalis : Saponaria .1275. Saraca indica : Asoka; Muyuju (Japanese); Asoka (Sanskrit).361

1276. Sarothamnus scoparius (or Spartium scoparium) [Papilionaceae] : Ginestra dei Carbonai (Tossica).1277. Sassifrax officinale or varifolium : Sassofrasso1278. Saussurea lappa : Costus; Kostwurz (Deutsch); Kushtha (Sanskrit).1279. Saxifraga aizoides : Sassifraga dei Ruscelli1280. Saxifraga ligulata (Bergenia ligulata) : Steinbrech (Deutsch), Pashanbheda (Sanskrit).1281. Saxifraga oppositifolia : Sassifraga a Foglie opposte1282. Scabiosa lucida : Scabbiosa, Scabiosa1283. Scabiosa succisa : Scabbiosa, Scabiosa1284. Schinus molle: Pepe rosa, Albero del Pepe del Brasile; Brazilian peppertree1285. Schizandra sinensis : Schisandra; Wu Wei Zi;1286. Schkuhria pinnata :Canchalahua1287. Scrophularia nodosa : Scrofularia maggiore1288. Scilla maritima (or Urginea maritima) : Scilla o Cipolla marina1289. Scilla nutans : Giacinto a Campanelle1290. Scleranthus annuus : Centigrani; Scleranthus1291. Scolopendrium officinale : Scolopendrio1292. Scoparia dulcis : Vassourinha1293. Scorzonera hispanica : Scorzonera1294. Scrophularia nodosa : Castagnola1295. Scutellaria baicalensis or latiflora : Scutellaria, Zucchetto, Papalina1296. Secale cereale : Segale Rye(english)1297. Sedum album : Erba pignola1298. Sedum dasyphyllum : Porcellana1299. Semecarpus anacardium : Anacardio orientale; Marking Nut Tree; Ostindis Chertintenbaum (Deutsch); Noix amarquer (French); Sumiurushinoki (Japanese); Bhallataka (Sanskrit).1300. Sempervivum aracnoideum : Semprevivo1301. Sempervivum tectorum : Semprevivo, Barba di Giove.1302. Sempervivum montanum : Semprevivo montano1303. Senapsis alba : Senape1304. Senecio aureus : Senecione1305. Senecium incanus : Senecione canuto.1306. Sequoia gigantea : Sequoia1307. Serapias longipetala : Bocca di Gallina1308. Serenoa repens : Palma nana, saw Palmetto.1309. Serenoa serrulata : Sabal1310. Sesamum indicum or orientale : Sesamo; Sesamum; Sesam (Deutsch); Sesame (French); Goma (Japanese); Huma (Chinese); Tila (Sanskrit).1311. Sheperdia canadensis : Soapberry1312. Sida cordifolia : Sida; Country Mallow; Marubakingojikuwa (Japanese); Kedong (Chinese); Bala (Sanskrit).1313. Sidalcea sp. : Mallow1314. Silene californica : indian Pink;1315. Silene cucubalus : Verzol, Verzini1316. Silene inflata : Silene1317. Silene vulgaris : Strigoli1318. Silybum marianum (or Carduus marianus) : Cardo mariano, Cardo di Maria, Cardo asinino, Cardo lattato1319. Simarouba amara or Simaruba officinalis : Simaruba1320. Simmondsia chinensis : Jojoba1321. Sinapis alba : Senape bianca1322. Sinapsis arvensis : Senape selvatica; Mustard (English)1323. Sisymbrium officinale : Erisimo1324. Smilax aspera, sarsaparilla officinalis or utilitis : Smilace, Salsapariglia, Barba di Magnano, Erba serretta,Rogo cervino, Sarsaparilla1325. Smilax china : Salsapariglia cinese.1326. Solanum dulcamara : Dulcamara (potenzialmente tossica)1327. Solanum indicum : indian Nightshade; Indische Nachtschatten; Shirosuzume-nasubi (Japanese); Housang kiue(Chinese); Brahati vanavrinktaki (Sanskrit).1328. Solanum lycopersicum : Pomodoro ;tomato(english)1329. Solanum melongena : Melanzana, Eggplant, Aubergine, Jia (Chinese)1330. Solanum nigrum : Morella; black Nightshade; Alpkraut (Deutsch); Inubozuki (Japanese); Ti'en kui tse(Chinese); Kakamachi (Sanscrit); (potenzialmente tossica)1331. Solanum quitoense : Lulo1332. Solanum paniculatum :Jurubeba362

1333. Solanum photeinocarpum : black Nightshade, Long Kui1334. Solanum surattense, xanthocarpum : Kantakari (English); Nacutsebattin (Deutsch); Kinginnasubi (Japanese);Kantakari (Sanscrit).1335. Solanum tuberosus : Patata, Potato, Ma Ling Shu1336. Soldanella alpina : Soldanella1337. Solidago virga aurea, canadensis : Solidago, Verga d'Oro; Golden rod1338. Sonchus oleraceus : Sonco1339. Sorbus aucuparia : Sorbo degli Uccellatori1340. Sorbus domestica : Sorbo domestico1341. Spartium scoparium (or Sarothamnus scoparius) : Ginestra dei Carbonai1342. Spartium juniceum : Ginestra di Spagna, di Maggio (Tossica)1343. Spathodea campanulata : Tulipano, Tulip1344. Specularia speculum : Specchio di Venere1345. Sphaeranthus indicus : east indian Globe Thistle; Munditika (Sanskrit)1346. Sphagum sp. : Sphagum Moss1347. Spigalia anthelmia : Spigalia1348. Spinacia oleracea : Spinacio; Spinach; Bo Cai (Chinese)1349. Spiraea aruncus : Spirea1350. Spiraea beauverdiana : Spiraca1351. Spiraea filipendula : Erba peperina1352. Spiraea ulmaria or Filipendula ulmaria : Olmaria, Ulmaria, Regina dei Prati1353. Spiranthes romanzoffiana : Lady's Tresses1354. Spirulina maxima : Spirulina1355. Stachys arvensis : Erba del Cancro1356. Stachys officinalis (or Betonica officinalis) : Betonica1357. Stachys sieboldi : chinese Artichoke, japanese Artichoke, Gan Lu Zi1358. Stachytarpheta jamaicensis :Gervagno1359. Stellaria media : Stellaria, Centonchio, goose intestine Vegetable, Chickweed, E Chang Cai (Chinese)1360. Sterculia acuminata : Cola noci, Noci di Cola.1361. Stevia rebaudiana : Stevia1362. Sticta pulmonaria ( or Lobaria pulmonaria) : Lichene polmonaria1363. Stirax officinalis : Benzoino,1364. Strophanthus hispidus or kombe or gratus : Strofanto1365. Strychnos nux-vomica : Noce vomica (Stricnina); Gemeinerbrech Nussbaum (Deutsch); Noizvomique(French); Machin (Japanese); Fan Mu Pieh (Chinese); Kupilu (Sanskrit); .1366. Stylidium schoenoides : Cowkicks1367. Styrax benzoin : Benzoino1368. Styrax officinalis (Altingia excelsa) : Storace, Storax, Rasamala (Deutsch), Sillhaka (Sanskrit)1369. Sutherlandia frutescens : Cespuglio del Cancro; Cancer Bush1370. Swertia chirata : Chiretta; Chireta (English), Chirata-kraut (Deutsch), Senburi (Japanese), Toyaku (Chinese),Kirata tikta (Sanskrit)1371. Symphytum officinale : Consolida maggiore, Erba del Cardinale; Consoude (French)1372. Symplocos racenosa Lodh Tree, Hainoki (Japanese) Lodhra (Sanskrit).1373. Sysymbrium officinale : Erisimo, Cima amarella, Erba cornacchia, Rapa selvatica, Rapino1374. Syringa vulgaris : Serenella, Siringa, Lilas ; Lilas (French).1375. Tabebuia avellanedae : Lapacho1376. Tabebuia species (impetiginosa, heptaphylla, avellanedae, rosea, serratifolia, cassinoides): Pau d'Arco, IpeRoxo, Taheebo, Lapacho1377. Tacca aspera : Tacca1378. Tamarix gallica : Tamerice1379. Tamarindus indica : Tamarindo, Tamarind, Tamarindenbaum (Deutsch), Tamarinier (French), Tomarindo(Japanese), Makkham (Chinese), Amlika (Sanskrit);1380. Tamus communis : Tamaro.1381. Tanacetum parthenium : Partenio1382. Tanacetum vulgare : Tanaceto; Tansy .(tossico)1383. Taraxacum officinalis (or Taraxacum dens leonis, or Leontodon taraxacum) : Tarassaco, Dente di Leone,Cicoria matta, Soffione, Pisciacane; Dandelion (English), Lowenzahn (Deutsch), Pissenli (French); Seiyotanpope(Japanese), P'u kung ying (Chinese), Dugdha feni (Sanskrit); .1384. Taxus baccata : Tasso, Albero della Morte; Biemi, Tree of Death (English); Eilec (Deutsch), Talispatra(Sanskrit); (Tossica)1385. Tecoma undulata : Tecoma1386. Tectona grandis : Teakwood363

1387. Telosma cordata : Cordate Telosma, Ye Lai Xiang (Chinese)1388. Tephrosia purpurea, maxima, laceolata : Tefrosia, Purple tephrosia (English), Nabankusafuji (Japanese), Nahtroi (Chinese), Sarapunkha (Sanskrit).1389. Terminalia arjuna : Arjuna myrobalan (English), Arjuna (Sanskrit)1390. Terminalia belerica : Belerica, Belleric myrobalan (English), Myrobalane (Deutsch), Bererikamiro baran(Japanese), Bang nut (Chinese), Vibhitaka (Sanskrit).1391. Terminalia chebula : Chebula, Chebulic myrobalan (English), Rispiger Myrobalanenbaum (Deutsch),Shirobarannoki (Japanese), He lile (Chinese), Haritaki (Sanskrit).1392. Tessaria integrifolia :Pajarobobo1393. Teucrium chamaedrys : Camedrio o Querciola1394. Teucrinum marum : Maro, Erba dei Gatti1395. Teucrium scorodonia : Scorodonia1396. Teucrium scordium Scordio1397. Thalictrum foliolosum : Gold thread, Tryamana (Sanskrit)1398. Thapsia garganica : Tapsia1399. Theobroma cacao : Cacao ; Cocoa (English)1400. Thuya occidentalis : Tuia, Albero della Vita (contiene turione, tossico)1401. Thymus serpillum : Timo Serpillo, Erba soltorella, Timo cedrato; Time(English)1402. Thymus vulgaris : Timo comune, Pepolina, Timo dei Giardini ; Time(English)1403. Thysanonthus manglesianus : Fringer Lily Twiner1404. Tiarella trifoliata : Laceflower1405. Tilia cordata, europaea, platyphilla, vulgaris :Tiglio; Tilleul (French)1406. Tilia tomentosa, argentea : Tiglio argenteo1407. Tinospora cordifolia : Tinospora, Ibonashitsu zurabuji (Japanese), Kuan chu hisng (Chinese), Guduchi(Sanskrit).1408. Trachyspermum ammi (or Carum copticum, or Ptychotis ajowan): Aiovano; Omum, Ajowan Kummel, Yamani1409. Tragopogon pratensis : Barba di Becco1410. Trapaeolum maius : Nasturzio1411. Tribulus terrestris : Albero sacro, small Caltrops; Croix de chevalier; Hamabishi (Japanese); Xinnao ShuTong, Chili (Chinese); Gokshura (Sanskrit).1412. Trifolium alpinum : Trifoglio alpino; Claver1413. Trifolium pratensae : Trifoglio pratense, Clover1414. Trifolium rubeus: Trifoglio rosso, Red Clover1415. Trigonella foenum graecum: Fieno greco; Fenugreek; Fenugre (French); Koroha (Japanese); Medhika(Sanskrit); .1416. Trillium chloropetalum : Trillium1417. Triteleia ixioides : pretty Face1418. Triticum durum : Frumento duro, Grano duro; wheat(English)1419. Triticum spelta :Farro;spelt(English)1420. Triticum turgidum : Frumento kamut (antico Egitto)1421. Triticum aestivum or vulgare : Frumento tenero, Grano tenero; soft wheat(English)1422. Tropaeolum majus : Nasturzio; Nasturtium; Capucine (French).1423. Tulipa clusiana : Lancetta1424. Tulipa silvestris: Tulipano bolognino1425. Turnera aphrodisiaca or diffusa : Damiana1426. Tussilago farfara : Farfara, Farfaro, Tussilagine1427. Typha latifolia : Stancia; cattail Pollen1428. Ulex europaeus : Ginestrone, Gorse1429. Ulmus campestris : Olmo1430. Ulmus fulva or rubra : Olmo rosso1431. Ulmus glabra : Olmo1432. Ulmus procera : Olmo inglese, Elm1433. Uncaria guianensis or tomentosa: Unghia di Gatto1434. Uragoga emetica : Ipecacuana1435. Urginea indica : indian Squill; Indische Meerzwiebel; Vana palandam (Sanskrit).1436. Urginea maritima (or Scilla maritima) : Scilla o Cipolla marina1437. Ursinia anthemoides : Ursinia1438. Urtica dioica (or Hurtica dioica) : Ortica grande; Ortie (French);1439. Urtica urens : Ortica1440. Utriculario vulgaris : Bladderwort1441. Vaccinium myrtillus : Mirtillo nero1442. Vaccinium uliginosum : blueberry Pollen; bog Blueberry364

1443. Vaccinum vitis idaea : Mirtillo rosso, Vite del Monte Ide1444. Valeriana jatamansi or wallichii : Valeriana indiana; indian Valerian; Indische Baldrian; Thuwarala(Japanese); Tagara (Sanskrit)1445. Valeriana officinalis : Valeriana, Amantilla, Erba gatta, Nardo selvatico; Valerian; Baldrian (English);Valeriane (French);1446. Valerianella olitoria : Valerianella1447. Vanda roxburghii or tessellata : Vanda; Rasna (Sanskrit)1448. Vanilla planifolia, aromatica, fragrans : Vaniglia1449. Veratrum album : Veratro bianco, Elleboro bianco (Tossica)1450. Veratrum nigrum : Veratro nero1451. Verbascum densiflorum : Verbasco1452. Verbascum thapsus : Verbasco, Candela Regia, Guaraguasco, Tasso Barbasso; Mullein1453. Verbena officinalis : Verbena, Berbena, Erba crocetta, Erba grana, Erba sacra, Menta di San Pietro; Vervain .1454. Vernonia aenulans : Vatke1455. Vernonia anthelminticum (Centratherum anthelminticum) : Vernonia, Aranjajira (Sanskrit).1456. Vernonia cinerea : Ash-colored fleabane; Yanbaruhikodai (Japanese); Sahadevi (Sanskrit).1457. Vernonia senegalensis : Omo-Kuka1458. Veronica alpina : Veronica1459. Veronica beccabunga : Beccabunga1460. Veronica chamaedrys : Veronica1461. Veronica officinalis : Veronica, The svizzero1462. Verticordia mitcheliana : red Feather1463. Viburnum lantana : Viburno, Lentaggine1464. Viburnum prunifolium : Viburno1465. Vicia faba : Fave, broad Bean, Can Dou (Chinese)1466. Vigna radiata : mung Bean, black Gram, green Gram, Lu Dou (Chinese)1467. Vigna unguiculata : black-eyed Pea, Cowpea, Dou Jiao (Chinese)1468. Vigna unguiculata : rice Bean (a variety of Cowpea), Fan Dou (Chinese)1469. Vinca alba: old Maid1470. Vinca major : Pervinca maggiore (Tossica)1471. Vinca minor : Pervinca (Tossica)1472. Vinca rosea : Vinca (Tossica)1473. Viola calcarata : Viola Farfalla1474. Viola odorata : Viola mammola, Violetta; wild Violet; Wildnechendes Veilchen; Niosumaire (Japanese);Banaphsha (Sanskrit).1475. Viola renifolia : white Violet1476. Viola tricolor : Violetta, Viola del Pensiero; blu elf Viola; Pensee (French);1477. Viscum album : Vischio .1478. Viscum album crataegi : Vischio di Biancospino1479. Vitex agnus castus (Agnus castus, Vitex trifoglia ) : Agnocasto, Pepe dei Monaci1480. Vitis quadrangularis (Cissus quadrangularis, Heliotropium indicum) : Conciaossa, Bone setter, Hirassa,Asthisanhari (Sanskrit)1481. Vitis vinifera rubra : Vite rossa, Uva nera; Grapes (English); Rosinen (Deutsch); Raisin (French); Budo(Japanese); P'u t'ao (Chinese), Draksha (Sanskrit);1482. Wahlenbergia capensis : Cape Bluebell1483. Wisteria sinensis : Glycine (French);1484. Withania somnifera : Winter cherry; Aswangandha (Japanese); Ashvagandha (Sanskrit).1485. Yucca schidigera : Yucca1486. Xanthorrea preissi : Balga blackboya1487. Xanthosia rotundifolia : southern Cross1488. Xanthoxilum fraxineuem : Frassino spinoso1489. Zantedeschia sp. : callia Lily1490. Zanthoxylum alatum : Gelbholz (Deutsch); Asakurazansho (Japanese); Chiao (Chinese); Tejpal (Sanskrit)1491. Zea mays : Mais, Granturco; sweet Corn, Corn, Maize; Mais doux (French); .1492. Zingiber officinalis : Zenzero; Ginger (English); Inguere (Deutsch); Gingembre (French); Shoga (Japanese);Chiang, Jiang (Chinese); Ardhrakam (Sanskrit);1493. Zinnia elegans : Zinnia1494. Zizania caduciflora : wild rice Stem, Jiao Bai (Chinese)1495. Zizyphus jujuba or martiana : Jijube Fruit; Stumpfblattriger Judendorn (Deutsch); Jujubier (French);Gnumatsume (Japanese); Hong tsao (Chinese), Badri (Sanskrit).1496. Zizyphus vulgaris : Giuggiolo; Jujube; Brustbeeren; Natsume (Japanese); Suan tsao (Chinese); Unnab(Sanskrit).365

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Curriculum vitae of the authorGiuseppe Nacci was born in Trieste, Italy, on 26th February 1964.He graduated in medicine at the University of Trieste in the academic year 1990-1991. In 1996 he specialized in Nuclear Medicine in Milan, where he took part in thefirst human experiments of the oncological Radio-Immuno-Therapy with Yttrium 90and Monoclonal Antibodies conducted by the Scientific Institute San Raffaele and theEuropean Oncological Institute.After patenting his industrial invention Synthesis and Use of biotin-DTPA-Gadolinium 157, 159 for radio-therapy (No. 01313103, class A61K051), hepublished “Therapy of tumours with Gadolinium 159 in Nuclear MagneticResonance”, 760 pages, Callerio Onlus Foundation, by the publishing house inTrieste “Italo Svevo”, May 2000 (only available in Italian under the title “La Terapiadei tumori con Gadolinio 159 in Risonanza Magnetica Nucleare”).In May 2006 he published a paper concerning the extreme dangerousness ofGenetically Modified Organisms on the American Journal of the Gerson Institute,San Diego, California (Gerson Heating Newsletters, Vol. 21, No. 3, May-June 2006,pages: 5,7,9, Part I, available at http://www.erbeofficinali.org/dati/nacci/studi/healg213.pdf ).Later in the same year he published the book “Diventa Medico di Te stesso”(“Become your own doctor”), by “Editoriale Programma, s.r.l., Padova, Italy.In January 2007 this book was awarded the following prize: “Best scientific book ofthe year 2006”, given “motu proprio” and unanimously by the Board of Councillorsof the Verein zur Förderung der Forschung Mare Nostrum – Research Institute(Association for Promotion of Research Mare Nostrum) in Wildon, Graz, Austria.More information athttp://www.mednat.org/The-best-book_Nacci.gifhttp://www.mednat.org/Miglior-libro_Nacci.gifIn October 2007 he received an honour known as the SIGILLO TRECENTESCO(the fourteenth-century Seal) from the city of Trieste in recognition of his passionatecommitment in his study and scientific research (http://trieste.rvnet.eu/2007/10/31/il-medicogiuseppe-nacci-riceve-il-sigillo-della-citta/#comments).433

In November 2007 he presented his book and 40 clinical cases at the PoliclinicoMilitare Celio in Rome (Celio Military Hospital) to the highest authorities of theItalian Military Health Service.Further details at:http://aloearborescens.tripod.com/libro-giuseppe-nacci.pdfhttp://www.medicinetradizionali.it/intervista%20nacci.pdfIn December 2007 he published one of his books on the Internet, “Thousand Plantsagainst Cancer without Chemo-therapy”. The book can be downloaded in Englishfree of charge from: http://www.mednat.org/cancro/nacci_english.pdfhttp://www.erbeofficinali.org/dati/nacci/studi/Thousand_Plants_against.pdfSince May 2008 this book in English has also been available on the web site of theUSA “National Health Federation” ( http://www.thenhf.com/about_us.html )In August 2008 he published on the Internet a paper on the extreme dangerousness ofthe nuclear plant in Krsko (Slovenia).http://www.ecceterra.org/docum.php?id=%201626On 13th September 2008 Dr Nacci took part in the annual Congress SANA inBologna explaining in eight points the extreme dangerousness of GMOs. He askedfor explicit intervention of the National Democratic Institutions in order to safeguardthe health of the Italian people and prevent GMOs from being authorised andintroduced also in Italy from January 2009.Further details at: http://www.erbeofficinali.org/dati/nacci/studi/SANA_Conference_091308.pdfIn October 2008 he was awarded the Seal of the city of Padua and received the price“Libraio della città di Padova 2008” (Padua Bookseller 2008).Further details at: http://www.erbeofficinali.org/dati/nacci/Premio_Padova.htmFrom October 1998 to December 2007 he hold the position of Director of theRegional Health Service at the Financial Police Administration of Friuli Venezia-Giulia.434

ALLEGATEDs435

ALLEGATED 1: The Case for a GM-free Sustainable WorldISP, www.indssp.org www.i-sis.org.ukwww.twnside.org.sg1. GM crops failed to deliver promised benefitsWhy GM Free?The consistent finding from independe esearch and on-farm surveys since 1999 is that GM cropshave failed to deliver the promised benefits of significantly increasing yields or reducing herbicideand pesticide use. GM crops have cost the United States an estimated $12 billion in farm subsidies,lost sales and product recalls due to transgenic contamination. Massive failures in Bt cotton of up to100% were reported in India.Biotech corporations have suffered rapid decline since 2000, and investment advisors forecast nofuture for the agricultural sector. Meanwhile worldwide resistance to GM has reached a climax in2002 when Zambia refused GM maize in food aid despite the threat of famine.2. GM crops posing escalating problems on the farmThe instability of transgenic lines has plagued the industry from the beginning, and this may beresponsible for a string of major crop failures. A review in 1994 stated, "While there are someexamples of plants which show stable expression of a transgene these may prove to be theexceptions to the rule. In an informal survey of over 30 companies involved in thecommercialisation of transgenic crop plants….almost all of the respondents indicated that they hadobserved some level of transgene inaction. Many respondents indicated that most cases of transgeneinactivation never reach the literature."Triple herbicide-tolerant oilseed rape volunteers that have combined transgenic and non-transgenictraits are now widespread in Canada. Similar multiple herbicide-tolerant volunteers and weeds haveemerged in the United States. In the United States, glyphosate-tolerant weeds are plaguing GMcotton and soya fields, and atrazine, one of the most toxic herbicides, has had to be used withglufosinate-tolerant GM maize.Bt biopesticide traits are simultaneously threatening to create superweeds and Bt- resistant pests.3. Extensive transgenic contamination unavoidableExtensive transgenic contamination has occurred in maize landraces growing in remote regions inMexico despite an official moratorium that has been in place since 1998. High levels ofcontamination have since been found in Canada. In a test of 33 certified seed stocks, 32 were foundcontaminated.New research shows that transgenic pollen, wind-blown and deposited elsewhere, or fallen directlyto the ground, is a major source of transgenic contamination. Contamination is generallyacknowledged to be unavoidable, hence there can be no co-existence of transgenic and nontransgeniccrops.4. GM crops not safe436

Contrary to the claims of proponents, GM crops have not been proven safe. The regulatoryframework was fatally flawed from the start. It was based on an anti-precautionary approachdesigned to expedite product approval at the expense of safety considerations. The principle of‘substantial equivalence’, on which risk assessment is based, is intended to be vague and ill-defined,thereby giving companies complete licence in claiming transgenic products ‘substantiallyequivalent’ to non-transgenic products, and hence ‘safe’.5. GM food raises serious safety concernsThere have been very few credible studies on GM food safety. Nevertheless, the available findingsalready give cause for concern. In the still only systematic investigation on GM food ever carriedout in the world, ‘growth factor-like’ effects were found in the stomach and small intestine of youngrats that were not fully accounted for by the transgene product, and were hence attributable to thetransgenic process or the transgenic construct, and may hence be general to all GM food. Therehave been at least two other, more limited, studies that also raised serious safety concerns.6. Dangerous gene products are incorporated into cropsBt proteins, incorporated into 25% of all transgenic crops worldwide, have been found harmful to arange of non-target insects. Some of them are also potent immunogens and allergens. A team ofscientists have cautioned against releasing Bt crops for human use.Food crops are increasingly used to produce pharmaceuticals and drugs, including cytokines knownto suppress the immune system, induce sickness and central nervous system toxicity; interferonalpha, reported to cause dementia, neurotoxicity and mood and cognitive side effects; vaccines; andviral sequences such as the ‘spike’ protein gene of the pig coronavirus, in the same family as theSARS virus linked to the current epidemic. The glycoprotein gene gp120 of the AIDS virus HIV-1,incorporated into GM maize as a ‘cheap, edible oral vaccine’, serves as yet another biological timebomb,as it can interfere with the immune system and recombine with viruses and bacteria togenerate new and unpredictable pathogens.7. Terminator crops spread male sterilityCrops engineered with ‘suicide’ genes for male sterility have been promoted as a means of‘containing’, i.e., preventing, the spread of transgenes. In reality, the hybrid crops sold to farmersspread both male sterile suicide genes as well herbicide tolerance genes via pollen.8. Broad-spectrum herbicides highly toxic to humans and other speciesGlufosinate ammonium and glyphosate are used with the herbicide-tolerant transgenic crops thatcurrently account for 75% of all transgenic crops worldwide. Both are systemic metabolic poisonsexpected to have a wide range of harmful effects, and these have been confirmed.Glufosinate ammonium is linked to neurological, respiratory, gastrointestinal and haematologicaltoxicities, and birth defects in humans and mammals. It is toxic to butterflies and a number ofbeneficial insects, also to the larvae of clams and oysters, Daphnia and some freshwater fish,especially the rainbow trout. It inhibits beneficial soil bacteria and fungi, especially those that fixnitrogen.Glyphosate is the most frequent cause of complaints and poisoning in the UK. Disturbances ofmany body functions have been reported after exposures at normal use levels.437

Glyphosate exposure nearly doubled the risk of late spontaneous abortion, and children born tousers of glyphosate had elevated neurobehavioral defects. Glyphosate caused retarded developmentof the foetal skeleton in laboratory rats. Glyphosate inhibits the synthesis of steroids, and isgenotoxic in mammals, fish and frogs. Field dose exposure of earthworms caused at least 50 percentmortality and significant intestinal damage among surviving worms. Roundup caused cell divisiondysfunction that may be linked to human cancers.The known effects of both glufosinate and glyphosate are sufficiently serious for all further uses ofthe herbicides to be halted.9. Genetic engineering creates super-virusesBy far the most insidious dangers of genetic engineering are inherent to the process itself, whichgreatly enhances the scope and probability of horizontal gene transfer and recombination, the mainroute to creating viruses and bacteria that cause disease epidemics. This was highlighted, in 2001,by the ‘accidental’ creation of a killer mouse virus in the course of an apparently innocent geneticengineering experiment.Newer techniques, such as DNA shuffling are allowing geneticists to create in a matter of minutesin the laboratory millions of recombinant viruses that have never existed in billions of years ofevolution. Disease-causing viruses and bacteria and their genetic material are the predominantmaterials and tools for genetic engineering, as much as for the intentional creation of bio-weapons.10. Transgenic DNA in food taken up by bacteria in human gutThere is already experimental evidence that transgenic DNA from plants has been taken up bybacteria in the soil and in the gut of human volunteers. Antibiotic resistance marker genes canspread from transgenic food to pathogenic bacteria, making infections very difficult to treat.11. Transgenic DNA and cancerTransgenic DNA is known to survive digestion in the gut and to jump into the genome ofmammalian cells, raising the possibility for triggering cancer.The possibility cannot be excluded that feeding GM products such as maize to animals also carriesrisks, not just for the animals but also for human beings consuming the animal products.12. CaMV 35S promoter increases horizontal gene transferEvidence suggests that transgenic constructs with the CaMV 35S promoter might be especiallyunstable and prone to horizontal gene transfer and recombination, with all the attendant hazards:gene mutations due to random insertion, cancer, reactivation of dormant viruses and generation ofnew viruses. This promoter is present in most GM crops being grown commercially today.13. A history of misrepresentation and suppression of scientific evidenceThere has been a history of misrepresentation and suppression of scientific evidence, especially onhorizontal gene transfer. Key experiments failed to be performed, or were performed badly and thenmisrepresented. Many experiments were not followed up, including investigations on whether theCaMV 35S promoter is responsible for the ‘growth-factor-like’ effects observed in young rats fedGM potatoes.438

In conclusion, GM crops have failed to deliver the promised benefits and are posing escalatingproblems on the farm. Transgenic contamination is now widely acknowledged to beunavoidable, and hence there can be no co-existence of GM and non-GM agriculture. Mostimportant of all, GM crops have not been proven safe. On the contrary, sufficient evidencehas emerged to raise serious safety concerns, that if ignored could result in irreversibledamage to health and the environment. GM crops should be firmly rejected now.Why Sustainable Agriculture?1. Higher productivity and yields, especially in the Third WorldSome 8.98 million farmers have adopted sustainable agriculture practices on 28.92 million hectaresin Asia, Latin America and Africa. Reliable data from 89 projects show higher productivity andyields: 50-100% increase in yield for rainfed crops, and 5-10% for irrigated crops. Top successesinclude Burkina Faso, which turned a cereal deficit of 644 kg per year to an annual surplus of 153kg; Ethiopia, where 12 500 households enjoyed 60% increase in crop yields; and Honduras andGuatemala, where 45 000 families increased yields from 400-600 kg/ha to 2 000-2 500 kg/ha.Long-term studies in industrialised countries show yields for organic comparable to conventionalagriculture, and sometimes higher.2. Better soilsSustainable agricultural practices tend to reduce soil erosion, as well as improve soil physicalstructure and water-holding capacity, which are crucial in averting crop failures during periods ofdrought.Soil fertility is maintained or increased by various sustainable agriculture practices. Studies showthat soil organic matter and nitrogen levels are higher in organic than in conventional fields.Biological activity has also been found to be higher in organic soils. There are more earthworms,arthropods, mycorrhizal and other fungi, and micro-organisms, all of which are beneficial fornutrient recycling and suppression of disease.3. Cleaner environmentThere is little or no polluting chemical-input with sustainable agriculture. Moreover, researchsuggests that less nitrate and phosphorus are leached to groundwater from organic soils.Better water infiltration rates are found in organic systems. Therefore, they are less prone to erosionand less likely to contribute to water pollution from surface runoff.4. Reduced pesticides and no increase in pestsOrganic farming prohibits routine pesticide application. Integrated pest management has cut thenumber of pesticide sprays in Vietnam from 3.4 to one per season, in Sri Lanka from 2.9 to 0.5 perseason, and in Indonesia from 2.9 to 1.1 per season.Research showed no increase in crop losses due to pest damage, despite the withdrawal of syntheticinsecticides in Californian tomato production.439

Pest control is achievable without pesticides, reversing crop losses, as for example, by using ‘trapcrops’ to attract stem borer, a major pest in East Africa. Other benefits of avoiding pesticides arisefrom utilising the complex inter-relationships between species in an ecosystem.5. Supporting biodiversity and using diversitySustainable agriculture promotes agricultural biodiversity, which is crucial for food security andrural livelihoods. Organic farming can also support much greater biodiversity, benefiting speciesthat have significantly declined.Biodiverse systems are more productive than monocultures. Integrated farming systems in Cuba are1.45 to 2.82 times more productive than monocultures. Thousands of Chinese rice farmers havedoubled yields and nearly eliminated the most devastating disease simply by mixed planting of twovarieties.Soil biodiversity is enhanced by organic practices, bringing beneficial effects such as recovery andrehabilitation of degraded soils, improved soil structure and water infiltration.6. Environmentally and economically sustainableResearch on apple production systems ranked the organic system first in environmental andeconomic sustainability, the integrated system second and the conventional system last. Organicapples were most profitable due to price premiums, quicker investment return and fast recovery ofcosts.A Europe-wide study showed that organic farming performs better than conventional farming in themajority of environmental indicators. A review by the Food and Agriculture Organization of theUnited Nations (FAO) concluded that well-managed organic agriculture leads to more favourableconditions at all environmental levels.7. Ameliorating climate change by reducing direct & indirect energy useOrganic agriculture uses energy much more efficiently and greatly reduces CO 2 emissionscompared with conventional agriculture, both with respect to direct energy consumption in fuel andoil and indirect consumption in synthetic fertilizers and pesticides.Sustainable agriculture restores soil organic matter content, increasing carbon sequestration belowground, thereby recovering an important carbon sink. Organic systems have shown significantability to absorb and retain carbon, raising the possibility that sustainable agriculture practices canhelp reduce the impact of global warming.Organic agriculture is likely to emit less nitrous dioxide (N 2 O), another important greenhouse gasand also a cause of stratospheric ozone depletion.8. Efficient, profitable productionAny yield reduction in organic agriculture is more than offset by ecological and efficiency gains.Research has shown that the organic approach can be commercially viable in the long-term,producing more food per unit of energy or resources.440

Data show that smaller farms produce far more per unit area than the larger farms characteristic ofconventional farming. Though the yield per unit area of one crop may be lower on a small farm thanon a large monoculture, the total output per unit area, often composed of more than a dozen cropsand various animal products, can be far higher.Production costs for organic farming are often lower than for conventional farming, bringingequivalent or higher net returns even without organic price premiums. When price premiums arefactored in, organic systems are almost always more profitable.9. Improved food security and benefits to local communitiesA review of sustainable agriculture projects in developing countries showed that average foodproduction per household increased by 1.71 tonnes per year (up 73%) for 4.42 million farmers on3.58 million hectares, bringing food security and health benefits to local communities.Increasing agricultural productivity has been shown to also increase food supplies and raiseincomes, thereby reducing poverty, increasing access to food, reducing malnutrition and improvinghealth and livelihoods.Sustainable agricultural approaches draw extensively on traditional and indigenous knowledge, andplace emphasis on the farmers’ experience and innovation. This thereby utilises appropriate, lowcostand readily available local resources as well as improves farmers’ status and autonomy,enhancing social and cultural relations within local communities.Local means of sale and distribution can generate more money for the local economy. For every £1spent at an organic box scheme from Cusgarne Organics (UK), £2.59 is generated for the localeconomy; but for every £1 spent at a supermarket, only £1.40 is generated for the local economy.10. Better food quality for healthOrganic food is safer, as organic farming prohibits routine pesticide and herbicide use, so harmfulchemical residues are rarely found.Organic production also bans the use of artificial food additives such as hydrogenated fats,phosphoric acid, aspartame and monosodium glutamate, which have been linked to health problemsas diverse as heart disease, osteoporosis, migraines and hyperactivity.Studies have shown that, on average, organic food has higher vitamin C, higher mineral levels andhigher plant phenolics – plant compounds that can fight cancer and heart disease, and combat agerelatedneurological dysfunctions – and significantly less nitrates, a toxic compound.Sustainable agricultural practices have proven beneficial in all aspects relevant to health and theenvironment. In addition, they bring food security and social and cultural well-being to local communitieseverywhere. There is an urgent need for a comprehensive global shift to all forms of sustainable agriculture.441

ALLEGATED 2Article by AGNES SINAI – Researcher.State of alert at Monsanto: after the Terminator scandal, the first killer plant in the history of agriculture (1), thecompany is torn between a policy of defense and strategic aggression. The problems began with the acquisition of theDelta & Pine Land Company, for the sum of 1.8 billion dollars; Monsanto thus came into possession of a patent which,thanks to a genetic engineering technique, enabled seeds to be ‘blocked’, inhibiting growth from one year to the next.Rafi (The Rural Advancement Foundation International) nicknamed this sterilization technique “Terminator”.Faced with opposition at an international level, Bob Shapiro, the managing director of Monsanto, announced thewithdrawal of the product, before he himself resigned. Since then the multinational organization has abandoned itsformer slogan “Food, health, future” - and is trying to make a new name for itself. Producing GMOs (they modestlyspeak of biotechnology, “Biotech”) is, in fact, a high risk business, both in terms of image and investments. Not tomention possible biological accidents: threats to biodiversity and the appearance of mutant insects, resistant to theinsecticides incorporated in transgenic plants (2).In the United States the Environmental Protection Agency (EPA) has already urged farmers to dedicate at least 20% oftheir land to conventional crops to enable the development of insects which are not resistant to the transgene Bacillusthuringiensis.Genetically “improved” organisms: they are sufficiently risky to explain why, in the merry-go-round of mergers,takeovers and restructuring, agro-chemistry, which includes vegetable biotechnologies (that is, GMOs), issystematically isolated from other sectors, so as to compartmentalize the transgenic risk. It is with this logic that Aventisis trying to separate from CropScience, its agrochemical branch: the company had marketed the transgenic maize“Starlink”, which can cause allergies in man.Although it is exclusively intended for animal feed, maize has been found in notable quantities in crisps and corn-flakeseaten by American consumers and in cakes made by Homemade Baking and sold in Japan. Still within this context,Syngenta, the first worldwide agrochemical group was founded in October 2000. It is the result of a merger between theSwiss company Novartis (a company well-known for producing medicines for chemotherapy) and the Anglo-Swedishcompany Astra-Zeneca (a company also well-known for producing medicines for chemotherapy), and will have aturnover of about 8 billion euros. Monsanto, after its merger with Pharmacia & Upjohn, a large pharmaceutical industry(this too is well-known as a producer of medicines for chemotherapy) now concerns itself only with agriculture, with aturnover which in 2000 reached 5.49 billion dollars. It ceded its important anti-arthritis medicine Celebrex toPharmacia, to specialize in the production of plant health products, agricultural seeds and, in particular, of geneticallymodified seeds. Monsanto is now, on a worldwide level, the second producer of seeds (after Pioneer) and of plant seedsafter Syngenta, and it is the number one producer of herbicides thanks to Roundup, the herbicide most widely sold in theworld (its turnover in the year 2000 was 2.6 billion dollars, almost half the group’s turnover). Its aim is to make thepublic accept transgenic products by convincing them that it is better to eat transgenic plants rather than ones whichhave been sprayed with pesticides (3). This is a strategy which is dressed up in philanthropic and ecological frills toovercome the last obstacles.With no consideration for ethics, Monsanto in January 2001 adopted a new code of behavior with five promises:‘dialogue’, ‘clarity’, ‘respect’, ‘sharing’ and ‘benefits’.According to the managing director of Monsanto-France, Jean-Pierre Princen, European consumers – the mostunwilling to accept GMOs – must understand that a genetically modified organism is nothing more than a geneticallyimproved organism. From here we have the birth of a new Monsanto, known inside the company as ‘plan M2’: its seedsare ecological and excellent for our health. Those who doubt it are simply misinformed.Today the teams from the multinational company are meeting in Ho-Chi-Minh City to sell their herbicides and to strikeup privileged relations with the Vietnamese media, scientists and members of the government. From the Philippines toArgentina they want carte blanche to operate, ‘Free to operate’ in Company slang.On the outside, therefore, they have to highlight the ecological quality of GMOs, of which the Company markets twovarieties.The first, the Bt gene, was developed from the Bacillus thuringiensis bacteria, and spreads its own insecticide toxins,which allows to reduce the vaporization of supplementary pesticides: a cotton crop called “Bt” will undergo two ofthem instead of six or eight. The second variety: Roundup Ready, was developed to resist the herbicide Roundup. In thisway, a farmer buys in a kit both the seed and the herbicide! Roundup was introduced by the company as abiodegradable product, and this has led to a lawsuit for false advertising from the Direction générale de la concurrence,de la consummation et de la repression des fraudes (Dgccrf) of Lyons (General direction for competition, consumerismand the suppression of fraud).Risk of sterility: in the United States, the EPA calculates that between 20 and 24 million kilograms of glyphosate isused annually (4). This product is present in huge amounts above all in the production of soya, grain, hay and in grazingland and land lying fallow. Since 1998 its use has increased by almost 20% a year. It is contained in Roundup and is theherbicide which is sold the most in the world earning for Monsanto about 1.5 billion dollars a year. The patent expired442

in 2000, but the company will keep a part of the monopoly thanks to the genetically modified plants, developed becausethey are tolerant to glyphosate. In Brittany this pesticide is one of the dangerous and regular pollutants: in October 1999it was 172 times above the norm in the Elorn, which provides a third of Finistère with drinking water, “which goes toprove that to say Roundup is biodegradable is a lie” said Dr. Lylian Le Goff, a member of the Biotechnological team ofthe association France Nature Environnement (France Nature Environment).The pollution by pesticides of the soil, of water and of rain water, of the whole food chain and the air has become aserious problem for public health which the French authorities have delayed in taking into consideration. As aconsequence, according to Dr. Le Goff, “It is absolutely necessary to apply the principle of precaution, and reconsiderthe drive to use pesticides, especially when helped by false advertising, which stresses the innocuousness andbiodegradability of products containing glyphosate”.The ingestion of pesticides by the consumer would be much higher if the genetically modified plants were morewidespread, given that they are impregnated by pesticides. Like dioxins, pesticides too – among which glyphosate – arenot biodegradable in the human body and constitute a real and invisible pollution (5). Their molecules accumulatevarious effects – allergic, neurotoxic, cancerogenous, mutagenic and hormonal - affecting male fertility.They have properties similar to female hormones, estrogens: globally the actions of these hormones are thought to beresponsible for the 50% decrease in sperm production over the last fifty years. If the decline in sperm production wereto continue, cloning would be forced on the human race by the year 2060! As well as being biodegradable, thetransgenic seeds which are compatible with Roundup are presented by Monsanto as ‘climate friendly’, given that,according to Monsanto, using them allows farmers to reduce or even to eliminate plowing, allowing huge doses ofcarbon gas and methane to be stored in the soil, with the consequent reduction by 30% in the emission of carbon gas inthe United States. It remains to be explained in what way a non transgenic cultivation would be less efficient… Onething is certain: there would be fewer profits, especially because standard cultivation would not use the herbicideRoundup.The sudden ecological vocation of Monsanto and the zeal of its “managing director for sustainable development”,Robert B. Horsch, converge with the interests of those who are selling the right to pollute, such as those land ownersin Montana who are already part of a coalition for the sale of the rights of carbon gas emission (6).If the phraseology Monsanto is using to the outside world centers on ‘tolerance’, ‘respect’ and ‘dialogue’, the languageused within is much cruder. Ted Crosbie, who is in charge of the vegetable development program, showed the truephilosophy of the company at a meeting of Monsanto Latin America in January 2001; he didn’t mince his words: “wewill deliver the pipeline and the future together”. To put it more clearly, they will flood the agricultural land availablewith GMOs – an irreversible wave. Latin America is, from this point of view, ‘a winning environment’. Monsanto hasestimated that in Brazil alone there are still 100 million hectares of land to ‘develop’.Unfortunately, this country continues to be reluctant to accept GMOs, laments Nha Hoang and his colleagues in theMonsanto group, responsible for the ‘free to operate’ strategy in Latin America: ”It is already the second producer inthe world of transgenic Soya, after the United States, and soon it will probably be the first”. It is the greatest economicpower in Latin America, but it is the only one where transgenic cultivation is not permitted. The judges declared theauthorization process for transgenic Soya Roundup Ready invalid, because no appropriate studies of the effect on theenvironment had been carried out; they maintained that the present agency responsible for the regulation ofbiotechnology had been constituted illegally. The statute of the company in question, CtnBio, is waiting for ratificationfrom the Brazilian Congress…. Its aim: to obtain the ‘pipeline’ for transgenic Soya to open the way for otherauthorizations which will allow it to put the following on the market: Yieldgard Maize, Bollgard Cotton and RoundupReady Cotton in 2002; Roundup Ready Maize in 2003; and Soya Insecticide Bt in 2005. In the meantime, Monsanto hasinvested 550 million dollars in building a factory which will produce its herbicide Roundup in the north-east of the Stateof Bahia. The strategy of the multinational is based on biotech acceptance: get GMOs accepted by society and then – orat the same time – inundate the market. To this end huge, aggressive advertising campaigns are launched. In the UnitedStates, television advertising time are bought directly by the propaganda machine of this field, the Council forBiotechnology Information. Monsanto is a cofounder of this organization, which centralizes the information relating to“the benefits of biotech”. “Television is an important means of getting biotech accepted. Therefore watch thecommercials and show them to your family and friends”, is Tom Helcher’s invitation; he is the director of thebiotechnology acceptance programs at Monsanto headquarters at Crève-Coeur (Missouri). Above all the Americanfarmers must be reassured, because they especially are worried about their foreign markets and they are hesitating tobuy genetically modified seeds.Even if Aventis Crop Science, Basf, Dow Chemical, DuPont, Monsanto, Novartis, and Zeneca Ag Products havelaunched huge advertising campaigns in the United States, they hesitate to do the same in Europe… In Great Britain,Monsanto’s commercial team has stated that it is satisfied with the results of its program of “talking campaign in favorof biotechnology” which after a study course guaranteed by the company enables its employees in the commercialsector to call themselves ‘experts’ in the subject and therefore go on to proclaim the merits of transgenic products tofarmers and schools. “There is nothing better than an excess of communication”, says Stephen Wilridge, managingdirector of Monsanto-Northern Europe.The school system is obviously a strategic element in the campaign to win over public opinion. After seeing theprogram Biotechnology Challenge 2000, which is partially financed by Monsanto, 33% of high school students in443

Ireland did research into the role of biotechnology in food production. Mobilized to give prizes and awards, DavidByrne himself, the European commissary in charge of the protection of consumer health, said that he “had no doubt thatthere was a link between the reluctance of consumers towards biotechnology and the lack of serious information on thesubject”. For 2001, the managing director of Monsanto-Ireland, Patrick Reilly, hopes for a wider participation, because,“these students are informed consumers and they will decide the future”.The multinational is not only learning to decode messages but also to recycle them and the expectations of society. Forsome months Monsanto has wavered between fanciful dialogue with and a deep-down rejection of the most importantnon-governmental organizations which contest the alleged quality of GMOs.Beginning with Greenpeace, defined by the Swiss inventor of golden rice, Ingo Potrykus, who works for Syngenta, as ‘acriminal against humanity’. Golden rice is a transgenic rice enriched with beta-Carotene (vitamin A), it is therefore asecond generation GMO; it has been called ‘medifood’, because of its alleged healing and nutritional qualities. As it isthe first therapeutic rice in the history of agriculture, the big biotechnological companies have been waiting a long timefor it: thanks to Golden rice, the last skeptics will no longer have any doubts about the fundamental, virtuous characterof the GMO project. Vitamin A, transgenically integrated, will be, in the end, the moral promoter of transgenic nutritionall over the world: who will venture to criticize its merits, when so many children in the third world suffer fromblindness because of a lack of beta-Carotene? Who will dare to doubt that the basic vocation in the transgenic seed tradeis nutritious, ecological and humanitarian?A fiendish assertion. The fact remains that the efficacy of golden rice for the populations concerned is hardly credible.Greenpeace and others have shown that it is absurd, making clear particularly with the help of micrograms, that toconsume a sufficient dose of Vitamin A every day, a third world child would have to complete a heroic feat: eat 3.7kilograms of boiled golden rice a day, instead of two carrots, a mango and a bowl of rice. At a press conference atBiodivision, the ‘Davos’ of biotechnology, held at Lyons in February 2001, we heard Potrykus’ public reaction: ”If youintend to destroy the experimental cultivation for humanitarian purposes of golden rice, you will be accused ofcontributing to a crime against humanity. Your actions will be scrupulously recorded in court and you will have, Ihope, to answer for your illegal and immoral acts before an international court”. Therefore, all those who doubt andcontest are criminals against humanity, they are even called ‘fiends of the earth’, a play on words of the English nameand the web site ‘Friends of the Earth’, which is much appreciated by the Monsanto staff.If political opposition is by nature ‘fiendish’, the ‘dialogue’ cannot go on. And yet the new Monsanto promises in itscode of conduct “to begin a permanent dialogue with all those who are interested, to better understand the problems andworries raised by biotechnology”.Behind this apparent solicitude lurks a real business strategy, that of double conformity: a conformity imposedafterwards, of the image of GMOs with the consumers’ expectations; consensus of opinions, by means of advertisingcampaigns and intensive communication. Because, if Monsanto’s one and only aim is to get its biopolitical projectpassed worldwide, the new Monsanto needs to demonstrate flexible ethics (obviously of a variable nature) seeing ashow it is the multinational itself which is setting the rules.To this end, the company has entrusted Wirthlin Worldwide, a worldwide specialist in business communication, the taskof ‘finding the means and ways of helping Monsanto to persuade consumers through reason and to motivate themthrough emotions’.This survey of people’s attitudes – called ‘the Vista project’ – is based on ‘monitoring consumers’ value systems’.Starting with the collection of data, the project elaborates a chart of four levels of thought (…): prejudices, facts,feelings and values. In the United States the results of the study have enabled messages to be devised which impress thegeneral public, and identify the importance of the argument supporting biotech : fewer pesticides on your plates”.In France the staff at Monsanto had to undergo this survey during a private interview where they assumed that theycould express themselves freely on what they thought of biotechnology, ‘for good or bad’, given that the objective wasto train “spokespeople who would use messages designed for the masses”.Genetic pollution. Access to genetic material and to the markets, with the benefit of total freedom of movement, is thedouble priority of the concept “free to operate”. To perfect a GMO costs between 200 and 400 million dollars and takesseven to ten years. As a return for such an investment, the multinational must obviously get an income, guaranteed bythe patent filed on the plant. To be able to sow again from one year to the next, royalties must be paid to the companyevery year. Every variety which has a GMO will be protected by the patent, which means that the farmer will have toacquire a license.The risk, in the short term, is to give the big seed producing companies the possibility of blocking the whole system,monopolizing the genetic patrimony throughout the world and creating an irreversible situation: the farmer will not beable to recover this patrimony in order to choose for himself again.This could also be a problem for Monsanto according to its own code of conduct, which promises to “make sure thatthird world farmers who are without resources can benefit from the knowledge and advantages of all forms ofagriculture, in order to improve food safety and the protection of the environment”.And here we have the generous concession to South Africa of a patent for transgenic sweet potatoes, in the hope ofspreading it all over Africa. "In Africa, with patience, we can widen our position with Yield Guard and also withRoundup Ready Maize. At the same time we should think about reducing or eliminating the rights to our technologywhich is suited to local crops, such as Sweet potatoes or cassava".444

A two-faced strategy where generous intentions are shown so as to get a foothold in a market which is not easilypenetrated, or less solvent but potentially dependant. A similar proceeding to that which led to the planting of goldenrice in Thailand by Syngenta (to make it freely available, it was necessary to remove 70 patents) or to use Indian milkcows doped with Monsanto’s Polisac (a forbidden hormone in the European Community), so as to conquer localmarkets which were not attracted to biotechnology.On the other hand, Monsanto has recently had Percy Schmeiser, a Canadian farmer, fined 10.000 Euro for 'pirating'transgenic kohl. He counterattacked by accusing Monsanto of accidentally polluting his fields of traditional kohl with atransgenic kohl tolerant to Roundup.But is the justice system capable of establishing the origin of genetic pollution? This case, which may not be the first,shows how difficult it is to prevent the accidental dissemination of GMOs.In France, such cases have been hushed up. In March 2000, different plots of conventional seeds of spring kohl sold bythe Advanta company, contaminated by GMO seeds of a different company, were planted in Europe. The plants weredestroyed. In August 2000, some varieties of winter kohl, checked by Dgccrf, were shown to be contaminated by GMOseeds. But no kohl GMO has yet been authorized for either cultivation or consumption in France. Already now,traceability is showing its weaknesses. Chance contamination is more and more frequent.A health worker in Lombardy has recently reported the presence of GMO in lots of Monsanto soya and Maize seeds.GMOs have been found in stocks of Maize seeds deposited at Lodi, near Milan. The pressure in Europe will increase,given that imported soya - which is largely transgenic - will replace the animal meal which is prohibited today.But is it not the aim of companies which produce transgenic seeds to see the disappearance of the non-GMO matrix,counting on the high costs of checking which this entails? Probably, in the next few years, farmers will have more andmore difficulty getting seeds from this matrix. World research is turning towards transgenic seeds and so it is possiblethat non-GMO varieties will end up being unsuitable to the evolution of agricultural techniques, if not completelyobsolete.One can therefore doubt the ‘transparency’ shown by Monsanto.The consumer depends on the information provided by the company. Every genetic construction is considered a patentand no legal obligation exists, for a company, to provide a private laboratory test for an analysis check. In France, thedescription of a genetic construction is filed at the Dgccrf which is the only organization that can do any analysis.However it does not have the right to do analysis on a commercial level, and therefore it cannot be used by consumersor companies for this purpose.The consumer will therefore have to be content knowing that companies market the seeds only after they have receivedauthorization that they can be used for human consumption and after undertaking to “respect the concerns of a religious,cultural and ethnic nature in the world and not use genes coming from man or animals in the agricultural productsdestined for consumption by man and animals”. The recent nomination to the management of the American EPA ofLinda Fischer, an ex-Monsanto manager, makes one think that not only is the new Monsanto outside the law but it aimsto make the law.Notes:(2) The risk of uncontrolled dissemination has been one of the reasons given by Josè Bové and two other farmers tojustify the destruction of transgenic rice plants in greenhouses at the Centre for International Cooperation andAgronomic Research Development (CIRAD), which occurred at Montpellier in 1999. The three defendants weresentenced on 15 March but they have appealed.(3) Some people from Editions de l’Institut national de la recherche agronomique (Inra) have published a cartoon (LaReine rouge, text and illustrations by Violette le Quéré Cady, Paris 1999), it would be a good idea for the personnel ofMonsanto to read it. It is a panegyric in favor of GMOs, in the name of the danger from insecticides.(4) Figures cited by Caroline Cox, “Glyphosate, Journal of pesticide reform, autumn 1998, vol. 18, n° 3, published bythe Northwest Coalition for Alternatives to Pesticides.(5) Read the work of Mohammed Larbi Bouguerra, The invisible pollution, Puf, Paris, 1997.(6) http://www.carbonoffset.org.445

ALLEGATED 3 : Mexican ClinicsPlease note that over the last year several Mexican Clinics have been temporarily closed. Some are allowedto re-open either completely or with some restrictions on what services they can provide. Bio-Pulse andCentury Nutrition were shut down in March 2001. For more information on these closures, see PeterChowka's article on Natural Healthline's website. We understand that many of the health inspectors inMexico about this time were fired and replaced. Apparently any clinic that does not have the appropriatepermits will be closed. If we hear about any other closures, we will post the information on this page. Otherclinics impacted have been: St. Jude (Jimmy Keller's clinic), Century Nutrition may be prohibited fromproviding some therapies. American Metabolics and American Biologics were temporarily shut down, butthey they all reopened. If any hospital is using "unproven" approaches or does not have all the properpermits, they may be temporarily shut down to get the proper permits. Any of the clinics that are found tohave their papers in order could potentially resume offering alternative therapies if the Mexican federalgovernment approves their requests to conduct experimental treatments. We have heard that they would belimited to a small number of patients and could not charge the patients for experimental treatments. We havenot confirmed this.See our January Newsletter for a write up on why people go to Mexican Clinics.If you do go to this clinic for treatment, be sure to let us know about your experience. Any feedback you canoffer may help others who are trying to decide which clinic to go to or which therapy to use.Advanced Medical Group has an office in El Paso, but the clinic is in Juarez, Mexico. They treat cancer,arthritis, diabetes, and heart disease using chelation, ozone, electrotherapy, laetrile, Koch, and BCG.Contact number is: (800) 863-7686. We do not have much information on this clinic, other than onecomplaint.American Biologic is an "integrated facility" that offers a wide variety of approaches, including laetrile,enzymes, chelation, oxygen therapies, bioelectrical therapies, nutritional therapy, hydrotherapy, andhyperthermia. They also have an office in Chula Vista California. American Biologics was also temporarilyshut down and were renting a small part of the old Hospital Del Mar/The Meridian Hospital, but we havebeen told they have reopened their clinic. We have received some positive and some negative commentsabout this clinic; mostly we have heard that they have become more conventional than in the past. Go to ourweb page on them for more information. 800-227-4473American Metabolic uses up to 150 different nontoxic medications and therapies to train the immune systemto eliminate cancer. The clinic was temporarily shut down, but they have advised us they have re-opened.We have received some positive and some negative comments about this clinic. Go to our web page onthem for more information - at http://www.cancure.org/american_metabolic.htm. 800-388-1083As of May 1st, the Gerson Institute has initiated a license agreement with a new treatment center co-ownedand operated by the two most knowledgeable and devoted Gerson physicians in the world: Dr. AliciaMelendez and Dr. Luz Maria Bravo. The new treatment facility, called Baja Nutri Care, is located in thePlayas area of Tijuana, Mexico. Call Tel. 619-685-5353 or 888-4-GERSON.Betania West Institute - Salvador Vargas M.D. in Tijuana. Vargas uses intravenous Laetrile with low-dosechemo, low-dose radiation, enzymes, Vitamins, etc. Tel: Toll free (888) 396-3130, 01152 664 638-8496 orFax: 01152 664 638-8413 or e-mail: betaniawest@hotmail.com U.S. Mailing Address: PO. Box 430430 SanYsidro, CA 92143-0430Bio-Medical Center (Hoxsey Clinic) in Tijuana was established in 1963 and was one of the first alternativecancer facilities in Mexico. They use Hoxsey tonic and salves to treat cancer. Best results are with skincancer (including melanoma) and breast cancer. 011-52-664-684-90-11BioMedics Institute in Tijuana offers hyperthermia and focused low dose radiation with advanced therapiesincluding brachytherapy, vaccine therapies, bio molecular therapies, Xenotransplantation (Cell Therapy),Apheresis, Ultraviolet Blood Irradiation, Cytokine Therapy, Electro-Magnetic Therapy, detoxification,Biological response modifiers, aloe vera, cesium, live cell therapy, and a nutritional program. They treatmany disorders, including: cancer, immune disorders including lupus and MS, cardiovascular problems,gastro-intestinal disorders, chronic fatigue, and Fibromyalgia. They have purchased a linear accelerator toallow them to do lower dosed "pinpoint" radiation. Their website is http://www.biomedicsinstitute.com/ or call(888) 626-8067 for more info.BioPulse Rejuvenation Clinics were known for their intense treatments to fortify the immune system. Theclinic in Mexico apparently did not have all the required permits to operate, so they are being prevented fromusing some of their therapies. They are currently focusing on a tumor marker test.Center for Immuno-Energy Therapy has moved from Canada to Reynosa as they felt there they would beable to allow the medical support that need for more rapid elimination of cancers. They provide individualswith chronic degenerative health problems, including immuno-deficiency diseases, neuroimmune diseases,and problematic infections assistance on how to achieve wellness. They use magnetic therapy, chelationtherapy, HANSI, enzyme therapy, photoluminescence/oxygenation of the blood, diet, herbs, and a special446

technique of intra-cancer injections. Phone 317-928-8885 for more details. We do not have many detailsabout this clinic.Centro Medico is a Windstorm Foundation Facility in Mexico. They tackle the "incurables" - emphysema,stroke, cancer, Lou Gehrig's, etc. using bio-oxidative therapies, oxygen therapy, vaccines, enzyme therapy,and herbal therapy. (Please note, this information came from Third Opinion by John Fink and has not beenverified. We believe the clinic has been closed.)Century Nutrition, Hulda Clark's research center in Mexico was temporarily shut down. They have reopened,but we don't know if there are any restrictions on what therapies they can use. For details call herassociation at 1-800-220-3741.CHIPSA - the home of the Center for Integrative Medicine, is a modern full-service hospital located Tijuana.CHIPSA treats all forms of cancer and is one of the few places in the world where patients can receive theColey's Toxins modalities. They use a modified Gerson Diet. They also use the VG-1000 vaccine, CoQ10,Ozone Therapy, Hyperthermia, Laetrile, DMSO, Wobe Enzymes, Chelation, Biological Dentistry, diet,supplements, and a variety of other approaches. 1-877-424-4772 - (1-877-4-CHIPSA)Contreras Clinic - See Oasis Hospital below.CSCT -Cell Specific Cancer Therapy also known as Zoetron is in Tijuana, Mexico has been shut down.Hospital Santa Monica, also known as the Donsbach Clinic, uses detoxification of the body, a rigorouscourse of immune enhancing and rebuilding therapies and many disease-specific treatment protocols,including hyperthermia, oxygen/ozone therapy, light therapy, ultraviolet blood purification, diet and nutrition.800-359-6547 or 619-427-3007Europa Institute of Integrated Medicine - Contact Dr. Carolyn Bormann, a consultant for them has an office inCalifornia, but the clinic is in Mexico. They treat cancer and also multiple sclerosis, lupus, CFIDS, viralsyndromes, and other immune dysfunctions. They use ozone, chelation, photoluminescence, UBI,hyperthermia, amino acid, enzyme, nutrition, hydrotherapy, neural therapy, and biologicals. (909) 338-3533.Genesis West Research Institute for Biological Medicine, previously run by Sergio Amescua, M.D., is nowbeing run by Jacob Swilling, PhD. They treat cancer and other chronic and degenerative illnesses.Treatments include detoxification, non-toxic dentistry, chelation therapy, oxygen and ozone, therapeuticnutrition, pH balance, and Bio-Energetic Medicine. www.cancertherapies.com 831-309-7988Gerson Healing Centers of America has an office in Bonita, California, but the main clinic is in the OasisHospital in Mexico. They not only treat cancer, but also heart disease, diabetes, multiple sclerosis, lupus,arthritis, and liver diseases. Therapy is Gerson, minerals, enzymes, liver extract, B12, acupuncture,botanicals, massage, and chiropractic. They offer a variety of educational programs. http://www.gerson.org/1-888-4-GERSONHarold Manner Center has an office in San Ysidro and a hospital in Tijuana, Mexico. They are best knownfor their use of laetrile in treating cancer. They were temporarily shut down but we have heard they have reopened.Hospital Bajanor S.A. de C.V. in San Diego also treats arthritis, heart disease, lung infections, and kidneystones. They use detoxification, amino acids, laetrile, DMSO, EDTA chelation, GH3, polypeptides, Hoxsey,germanium, and nutrition. www.bajanor.com. 1-888-294-0342Hope4Cancer Institute run by Antonio (Tony) Jimenez, M.D. is in Tijuana. They use Polyatomic Aphaeresis,Carnivora, PolyMVA, oxygenation, alkalinizing, detoxify, anti-tumor agents, stimulate immune status,nutritional program, and prayer. Medical dentistry is also done here. Their website ishttp://www.hope4cancer.com/, or email drtony@hope4cancer.com. Tel: 011 526 680-6654 or Fax: 011 526680-6654. Patient Response line at 800 670-9124. We do not have much information on this clinic.I.M.A.Q - Dr. Castillo - Dr. Isai Castillo Ramos in Tijuana treats cancer, diabetes, arthritis, and many chronicdiseases. He uses IVs, Hoxsey, laetrile, nutrition, etc. Costs to go to his clinic are very low compared tomany other clinics. 800-296-9881 http://www.drcastillo.com/Institute of Chronic Disease is run by Dr. Gustavo Andrade. They treat cancers, Candidiasis, ChronicFatigue Syndrome and Herpes. Therapies include conventional therapies, vitamins, enzymes, laetrile,ozone, shark cartilage, Hydrazine Sulfate, and chelation. http://www.bajaonline.com/drandrade/programs.htm011-526-680-9292.International Bio Care Hospital and Medical Center (IBC) in Tijuana uses a program founded on a broadbasis of lifestyle changes, of which nutrition is among the most important to help rebuild the immune system.They also use UBIT - ultraviolet blood irradiation, bioelectrical repolarization (BER) and anti-fungal therapy.They are a full in-house hospital. (800) 785-0490 http://www.ibchospital.com.International Center for Medical & Biological Research, Inc. has an office in San Diego and clinic inMexico. They treat prostate, breast, liver, lung, and bone cancers, testicular, melanoma, multiple myeloma,and leukemia. They use electromagnetic treatment according to Nordstrom and Rife, chelation, and thecenter's own vaccines. Phone: Dr. Suzanne Henig at (619) 481-5284 or 011-52-66-30-18-53. We don't knowvery much about this clinic.447

International Medical Center in Juarez Mexico. They treat cancers, heart disease, circulatory problems,arthritis, diabetes, amyotrophic lateral sclerosis, chronic fatigue, Epstein-Barr virus, candidiasis,hypoglycemia, Parkinson's disease, Alzheimer's disease, and most chronic degenerative diseases.Treatments include chelation, hyperbaric oxygen, electrotherapy, hydrotherapy, colon therapy, ozonetherapy, detoxification, respiratory therapy, physical therapy, acupuncture, shark and bovine cartilage, Kochvaccine, enzyme and nutritional therapy, and immunotherapy. Phone: (800) 621-8924. We don't know verymuch about this clinic.Medico Cirujano in Tijuana is run by Dr. Perez Garcia. He uses IPT - Insulin Potentiation Therapy fortreating cancer. 18 years of IPT experience. Dr. Garcia also has a training program. www.iptq.com 011-52-(664)-686-5473.Mission Medical has a clinic in Tijuana. They can be reached by calling (619) 662-1578. Their primarydoctors are James Gunier, H.M.D., Ph.D.; Roberto Diaz, M.D., Ph.D.; N. They treat all forms of cancer aswell as AIDS, arthritis, Alzheimer's, stroke, paralysis, rare neurological diseases, and chronic degenerativediseases. They use nontoxic therapies; tumor reduction therapy, tumorin, therapeutic immunology, RNAregeneration, Koch, Ridasa, immune therapy, rare homeopathic tumor related remedies, HCL mineralchloride infusion, super IV drops, herbology, Rife, Dia-Pulse, poultices, counseling, diet, lifestyle, and apersonalized follow-up program. We don't know very much about this clinic.Monterrey Clinic, formerly called the Davidson Cancer Clinic, is run by James Gary Davidson. Apparentlyhe is under indictment. We do not recommend dealing with this clinic.New Hope Clinic - Dr. Stephen Linsteadt - in Tijuana is best known for their use of BioElectric CancerTherapy and BioResonance protocols from Germany. They are an integrative medical facility utilizing thelatest techniques in the treatment of cancer, heart disease, arthritis, and most chronic degenerativediseases. Treatments include BioElectrotherapy, BioResonance, photoluminescence, oxygenation,chelation, immune system modulators and auto-vaccinations, enzyme and nutritional therapy.Oasis of Hope Hospital - also known as Contreras Clinic is in Tijuana Mexico. (note: Gerson Center nowoperates out of its own clinic.) They are currently the only facility authorized by The Issel's Foundation to useuse the name of Issels and Issels Treatment. They have been treating cancer patients over 35 years.USA Phone: 1-888-500-HOPE (4673)International Phone: 011-52-664-6316111Program for Studies of Alternative Medicines in Jalisco is run by Hector E. Solorzano, M.D., Ph.D. It wasestablished in 1985 and treats cancer, arthritis, lupus, AIDS, diabetes, migraine, multiple sclerosis, andchronic renal failure using216 different alternative therapies, including, DMSO, chelation, enzymes, amino acids, shark cartilage,electromagnetism, moxibustion, and lasers. (Please note, this information came from Third Opinion by JohnFink and has not been verified.) Phone: 011-378-13532; -15133; -15134.Providence Hospital, located just of outside of Tijuana, was founded in 1996 by Dr. Gary Tarasov. In additionto treating cancer, Providence Hospital also offers a unique vaccination program for those currently withoutcancer. 619-972-383.San Diego Clinic in Tijuana uses a "Total Integrative Medicine Program" - the use of all major forms ofalternative and complementary therapies to treat specific cancers and other degenerative conditionsincluding MS, ALS, and CFS. Therapies include detoxification, nutritional programs, boosting the immunesystem, enzyme therapy, Biological (Biological Response Modifiers, especially cytokines) and ImmunologicalTherapies, and a variety of vaccines. Costs to go to his clinic are very low compared to many other clinics.Contact: Vincent Gammill at (858) 523-9144 for more information on this clinic.Sanoviv is a health resort on the Baja Coast at Rosarita Beach. They are a modern, beautiful facility right onthe ocean that incorporates modern diagnostics with a variety of treatment programs. They treat manycancers as well as many degenerative diseases. They believe the body has the power to heal itself whenprovided with the proper nutrients and when relieved of its accumulated toxic burdens. Their website iswww.sanoviv.com or for more info call (800) SANOVIV.Stella Maris Clinic in Tijuana offers a basic 21 day therapy which includes detoxification and individualizedprotocols to rebuild the immune system. Dr. Alvarez, who runs this facility, is one of our favorite doctors. 800-662-1319.Lawrence H. Taylor, M.D., is working as a consultant with BioMedics Institute in Mexico. (above) Hisprogram calls for a reordering of a patient's body and mind, from immune system support and detoxificationto emotional counseling and a complete nutritional program. (888) 626-8067 or (909) 303-3250.Clinic Tours:If you would like to tour some of the clinics in Mexico, there are several organizations that provide tours,including:CCS Cancer Clinic Tours in Modesto - 209-529-4697448

Private Cancer Tours aka Alternative Health ToursP. O. Box 530218 San Diego, CA 92153-0218Phone: (619) 475-3834 Fax: (619) 475-0753E-mail: getwell@healthtours.comWebsite: www.healthtours.comhttp://www.alternativemedicaltours.com/ - 1-800-788-9050 - However, we understand they often only tourAmerican Biologics and Hospital Meridian.***********************The information on this page is provided by The Cancer Cure Foundation based on information we havereceived from a variety of sources, including the clinic itself, feedback from people who have gone to theclinic, and in some cases from clinic tours. The listing of a doctor or clinic here does not signify anendorsement by the Cancer Cure Foundation, unless we have indicated it. We encourage you to check outeach clinic by visiting the clinic if possible, talking to people who have gone to the clinic (ask the clinic forcontact information of people who have gone to the clinic), and by checking with other organizations as towhat they know about the clinic. There are also some forums you can join to get feedback from others. Wewould also be happy to tell you what we know about any of these clinics.If you do go to any of these clinics for treatment, be sure to mention you heard about them through TheCancer Cure Foundation, and be sure to let us know about your experience, positive or negative. Anyfeedback you can offer may help others who are trying to decide which clinic to go to or which therapy touse.Back to the Directories Page.List of other Clinics in Center/South AMERICAOffering Alternative TherapiesThe listing of a doctor or clinic here does not signify an endorsement by the Cancer Cure Foundation. Wewill add additional information about each clinic as soon as our staff has a chance to contact them. If wehave a separate page for the clinic, there will be a hyperlink to that page. In addition, we are putting togethera database that will include details including contact information, size of clinic, costs if available, whetherthey take insurance, etc. If you would like us to check our database to see if we have this informationavailable on a particular clinic, or if you would like us to contact a clinic on your behalf, contact our office byemailing us at ccf@cancure.org, or by calling us at (800) 282-2873 or (805) 498-0185 9-5 PST.If you do go to a clinic for treatment, be sure to let us know about your experience. Any feedback you canoffer may help others who are trying to decide which clinic to go to or which therapy to use.BahamasImmuno-Augmentative Therapy Centre in Fort Lauderdale has a clinic in the Bahamas. The goal of lAT is tobuild systemic levels of tumor killing immune complexes to the levels that would be found naturally in abalanced immune system - their credo is "we treat immune systems, not cancer." (242) 352 7455.http://www.iatclinic.comCubaIn Havana, Ozone Research Center - Carlos Hernandez Castro, Ph.D., also treats senile dementia,Parkinson's, arthritis, diabetic neuroangiopathy, and glaucoma. Primary therapy is ozone therapy. 011-53-721-0588449

EcuadorRobert B. Wickman DO ND is Quito is an Osteopathic doctor, specializing in diseases of the nervoussystem and spinal column. He has treated many cancers, even advanced. He uses IPT therapy, diet andsupplements. Rbw66_2000@yahoo.com 593-2-241-274San SalvadorHospital de Diagnostico, a "boutique hospital" using art and music and other extra medical forms ofgentleness and strength to add to its ambiance of healing, has added HANSI AT to its list or therapiesoffered. To assure El Salvador of its integrity, it will be tested further there under the auspices of StanfordUniversity, while other tests are beginning in St. Petersburg, Russia, in cooperation with the Pasteur Instituteand the World Health Organization. Dr. Rodrigo Brito, president and director of Hospital de Diagnostico, andhis staff will administer the treatment of late stage cancer along with the facility's arsenal of advancedequipment for cancer therapies. Dr. Cesar Bertacchini, oncologist and professor of oncology in BuenosAires, Argentina, will join them as medical director of the program. Patients will be received beginning August1, 2002. For additional information, contact Dr. Colleen Green at the U.S. Information Office (941) 358-8500.South AmericaCentro De Rejuvenecimiento Cellular Por Oxigenoterapia Hiperbarica in Palmira, Colombia doesadjuvant HBO treatment, especially for those receiving radiation or chemotherapy, mostly breast andprostate cancers. They also use nutritional and vitamin therapy. Tel. (57 ) (02 ) 272 45 44 , FAX : (57 ) (02 )273 32 28In Cali there are two clinics that use allopathic and alternative, including Hyperbaric, Bio Energetic Medicine,homeopathic medicine, acupuncture, chelation, vitamin and nutritional medicine. These two clinics are:Clinica de Medicina Biologica del Dr. Arturo - Tel (57) (02) 554 12 87 and Medicina Bio Energetica,Dr. Elias Bechara Simancas - Tel (57 ) ( 02 ) 661 78 36 or email ebechasim@hotmail.com.450

List of Clinics in the United StatesOffering Alternative TherapiesThe following doctors, clinics and hospitals provide alternative treatments for cancer in the United States. Ifyou are interested in a clinic outside of the United States, go to Clinics Outside of the US, or to our list ofMexican Clinics, which we have recently put on its own web page. We also have a list of clinics that use acombination of alternative and conventional therapy to treat cancer. If you are interested in working with anaturopath, we have a web page devoted to naturopathic physicians and traditional naturopaths. If youwould like to find a homeopath who works with individuals with cancer, go to our page devoted tohomeopaths.The listing of a doctor or clinic here does not signify an endorsement by the Cancer Cure Foundation. Wewill add additional information about each clinic as soon as our staff has a chance to contact them. If wehave a separate page for the clinic, there will be a hyperlink to that page. In addition, we are putting togethera database that will include details including contact information, size of clinic, costs if available, whetherthey take insurance, etc. If you would like us to check our database to see if we have this informationavailable on a particular clinic, or if you would like us to contact a clinic on your behalf, contact our office byemailing us at ccf@cancure.org, or by calling us at (800) 282-2873 or (805) 498-0185 9-5 PST. We havebeen asked to add contact information to our website - We are still confirming this information, so if you findany of the phone numbers, websites, or addresses are not accurate, please let our webmaster know.Some people find it helpful to visit several clinics before choosing one. There are several companies thatoffer clinic tours, especially to the clinics in Mexico. If you would like us to put you in touch with thesecompanies, we can help you arrange this.If you do go to a clinic for treatment, be sure to let us know about your experience. Any feedback you canoffer may help others who are trying to decide which clinic to go to or which therapy to useAlaska:USAElisabeth-Anne Cole, M.D., Ph.D., in Kenai treats immune dysfunction presenting as cancer-all phases, alltumors, at any location in the body, as well as AIDS, HIV, lupus, multiple sclerosis, Parkinson's disease,rheumatoid arthritis, chronic fatigue syndrome, Crohn's disease, diabetes, arteriosclerosis, and fibromyalgia.She uses nontoxic immune system enhancement and balancing through nutritional supplementation, diet,detoxification, oxygenation, and bioenergetic/electromagnetic strengthening, as well as acupuncture, neuraltherapy, and sclerotherapy. 907-283-7740.Brian Le Compte, MD in Anchorage may use laetrile and IPT as part of his approach. phone: 907-344-7775or email: kininigen@hotmail.com.Arizona:Aeris Health Systems (AHS) in Tempe, AZ is run by Dr. Charles A. Knouse, D.O. He specializes inalternative cancer therapies, stressing multi-modal integrated cancer treatment. Some of his approachesinclude: Intravenous vitamin C, Insulin-Potentiation Therapy (IPT) with either very low-dose chemotherapyor very high-dose intravenous vitamin C, intravenous alpha lipoic acid, supplements, and nutrition andlifestyle counseling. For more information, go to his website at http://www.aerisclinic.com/. To reach him byemail - info@aerisclinic.com. By phone: 480.446.8181 or toll free: 877-585-7684.Aidan Incorporated in Tempe is a research-based facility that provides complementary and uniqueapproaches to treating cancer. Their treatment approach is designed to help stimulate a person’s ownimmune system to recognize and attack tumor cells. They believe defective or inadequate antigen (cellsurface information) presentation and inadequate T cell recognition of tumor cells are the root cause of thedevelopment of most malignancies. They also believe that people with malignancies can have a much higherrequirement of vitamin C and that vitamin C, given in adequate intravenous doses, can exert potent anti-451

tumor effects. They also use C-Statin as an anti-angiogenesis inhibitors to enhance the effectiveness ofimmune-based therapies. They also use a homeopathic form of dendritic cell therapy. Their website isjust www.aidan-az.com or call 800-529-0269. A write up on this clinic is in Alternative Medicine Magazine'sNovember issue. To order a copy, go to http://www.alternativemedicine.com.BioImmune (formerly CancerOption.com) Arnold Takemoto, Presidentwww.canceroption.com (888) 663-8844 or (480) 778-1618. They really aren't a clinic, but they provide protocolsto use at home. They can also recommend clinics that are using their protocols. We have heard they have agood protocol for leukemia.The First Resort in Green Valley, AZ is run by Bryan McConnell, ND. It is mostly a general practice, but hedoes treat cancer using a variety of approaches. He uses IV vit C, IPT, diet, exercise, colon hydrotherapy,detox, cleansing, chelation, EDTA, trained in Gerson and other diet programs, juicing, classical homeopathy,darkfield microscope, hoxsey, essiac, bio-oxidative therapies, constitutional hydrotherapy, hydrazine sulfate,Poly MVA for cancer cytotoxic action, DMSO, and dry sauna similar to Hubbard protocol. Call 877- 399-9212 or 520 399-9212. http://www.thefirstresortaz.com/Integrative Health Care, PC, in Scottsdale AZ, is run by Alan Christianson, ND treats almost any type ofcancer, even later stage cancers. They use metabolic therapies for those not undergoing conventional care.For those doing conventional treatments, they use intravenous nutrition and botanical meds to prevent sideeffects and help efficacy of chemo/radiation. Call (480) 657-0003 or go to their website athttp://www.integrativehealthcare.com/.Effective February, 2001, Immune Therapies International (ITI) will be operating two clinics that will offertreatments for people with cancer. One is in Dunwoody, Georgia (Atlanta area) and the other is in Tucson,Arizona. Their approach uses state-of the art medicine and diagnostic testing which will mobilize the body,mind, spirit, and emotions toward ongoing health. Each participant's individualized treatment plan isdeveloped by Dr. Jesse A. Stoff M.D. (H), Director of Integrative Medicine and his team of healthprofessionals. ITI's medical model is integrative medicine at its best. For information on their facilities, go tohttp://www.immunerecovery.com/facilities.htm or call them at 866-471-4743.Jesse Stoff, M.D., is no longer associated with Solstice or IntegraMed. He is training doctors and setting uptreatment protocols for Immune Therapies International (ITI).New Hope Medical Center in Scottsdale uses alternative methods to treat immune deficient illnesses such ascancer. Dr. Fredda Branyon, Director, and Dr. Mario Galaburri, NMD, agree that a physician should neverjust treat the symptoms of the illness, but treat the individual as a whole. Dr. Ronald Peters, MD, MPH, hasalso joined the New Hope team, reinforcing New Hope Medical Center’s commitment to offer its patients anaggressive, non-invasive approach to the treatment of cancer and other auto-immune diseases. Dr. Petershas 15 years of experience in integrative medicine and nutritional biochemistry, with special emphasis in thetreatment and prevention of chronic disease. Phone (480) 556-0182, toll free: (888) 518-7788, or go to theirwebsite at http://www.newhopemedicalcenter.com/.Dr. Michael Uzik, ND. works with Arizona Naturopathic Physicians in Tucson AZ treats a wide range ofconditions, including HIV, cancer, MS, chrones, etc. using nutritional IVs, mistletoe, ambrozile (oleander),copper reduction therapy for anti-angiogenesis, chelation, diet, herbs, heavy metal detox, etc. He is also anND for Southern AZ AIDS Foundation. He only sees patients if they are under the care of an oncologist. 520-546-2321.California:For a list of alternative practitioners in Ventura County, go tohttp://www.cancure.org/alternative_practitioners_ventura.htm. This list includes more than just doctors - it willinclude massage therapists, Reiki and QiGong practitioners, naturopaths, and more.Advanced Medical Clinic, in Encino is run by Ilona Abraham, M.D. They also treat heavy metal toxicity, andchronic depression of the immune system. They use chelation, mercury detoxification, homeopathy, andnutritional supplements. Their website is www.antiaging-techniques.com. 818-345-8721452

Alternative Medicine Associates, in Santa Barbara also treats chronic pain, arthritis, cardiovasculardisease, Parkinson's, and Alzheimer's. They use Chinese herbs, acupuncture, nutrition, osteopathy,Ayurveda, and QiGong. Phone: 805-569-8825.American Biologics has an office in Chula Vista, but the clinic is in Mexico.American Metabolic Institute has an office in San Diego, but the clinic is in Mexico.Bio-Medical Center (Hoxsey Clinic) has an office in in San Ysidro, but the clinic is in Mexico.Michael Broffman, an herbalist and acupuncturist works at the Pine Street Medical Clinic in San Anselmo,CA. He uses traditional Chinese medicine with cancer patients as an adjunct to mainstream treatments -(TCM) & supplement program. (415) 485-0484Casdorph Clinic of Long Beach, run by Richard Casdorph, M.D., Long Beach, mainly treats cardiovasculardisease, toxic metal exposure, and practices environmental medicine. He uses EDTA chelation, andnutrition. 562-597-8716Center for Well Being and Integrative Medicine Clinic in Westlake Village is run by Dr. Norman Narchi.He has over 25 yrs. in practice Parkinson's, Alzheimer's, fibromyalgia, chronic fatigue, ADD combination ofhealing techniques and conventional practices. He often uses QiGong in his treatment protocols. 818-879-0555 or 818-879-5508 www.centerforwellbeing.com or email nnarchi@centerforwellbeing.com.Daniel Beilin, O.M.D., L.Ac., in Aptos treats cancer and internal medicine, using enzyme, diet,polypeptides, alkalization, Sanum Therapy, and Chinese herbs. He also uses thermography to test forcancer. Contact info: 831-685-1125 or dbeilin@got.net.Contreras Clinic (Oasis Hospital) has an office in Chula Vista, but treat in Mexico.Europa Institute of Integrated Medicine - contact a consultant for the clinic - Dr. Carolyn Bormann, who hasan office in Twin Peaks, but the clinic is in Mexico.Genesis West Research Institute for Biological Medicine has an office in Irvine, but the Clinic is in Tijuana,Mexico.Gerson Healing Centers of America has an office in San Diego, but the main clinic is in Mexico at Oasis ofHope. The diet is used to treat autoimmune disorders, CHD, and Type II diabetes using Gerson's Diet, Issel'streatments, and Danopoulos' protocols. They have clinics in Mexico, Canada, and the UK. See ourorganizations page. 1-888-4-GERSON www.gerson.org.David Getoff, ND, a Naturopath and Board-Certified Clinical Nutritionist in Jamal, CA. treats cancer and avariety of other conditions with nutritional support. He utilizes numerous modalities from around the world tosupport your body's ability to heal itself. 619-468-6846 http://www.naturopath4you.com/ca.htmHarold Manner Center has been temporarily shut down. They are best known for their use of laetrile intreating cancer. The clinic is in Mexico.Holistic Medical Center in Los Angeles is run by Emil Levin, M.D. He also treats viral infections, parasites,allergies, asthma, hepatitis, diabetes, and more, Therapies include infusion, homeopathic, chelation, andvitamins. Phone: 213-650-1789.Holistic Resource Center in Agoura Hills, CA - Dr. Alan Schwartz, MD. and a number of holisticpractitioners including a chiropractor, naturopaths, homeopath, and a massage therapist. They can do bioelectricalscreening, NAET allergy removal, and they provide nutritional support including IVs, diet programs,Poly MVA, PC SPES, homeopathy, and more. 818-597-0966 or fax 818-597-8668.Douglas Hopper, MD in Santa Monica specializes in family practice, treating ADD, allergies, Alzheimer's,arthritis, CFS, cancer, fibromyalgia, Parkinson's, thyroid disorders, and many other conditions. He uses a453

wide range of approaches. Note: He will be doing a special program to test the use of hi vitamin C, andother supplements against cancer. The program is being funded so there is no charge to participate. Youmight want to contact him for information. He can be reached at 310-581-8585, by fax at 320-215-4650,website http://www.yourowndoctor.com/aboutus.asp?site=2092&doc=2092,or email: hoppermd@alumni.princeton.edu.Richard P. Huemer, MD in Quartz Hill, has retired. He is still providing medical advise via the internet. Heworks with athersclerosis, chemical sensitivities, autism, and chronic fatigue syndrome. He uses nutrition, IVvitamin C, high-dose nutrients, and BCG. His website is http://www.huemer.yourmd.com.Orange County Immune Institute in Huntington Beach has a "complementary" approach to exploit thebiochemistry and genetics of cancer cells and how they differ from normal cells. The emphasis is oneliminating toxicity and building the immune system. Therapies used include: chelation, hyperthermia,BioResonance devices, diet and nutrition, detoxification, nutraceuticals, light, and immunotherapy. In somecases, different forms of chemotherapy are used. For more information about this clinic and for a link to anarticle about them, see a write up on our website at http://www.cancure.org/immune_institute.htm. You canalso call them at 714-842-1777 or go to www.drferre.com.Dr. Shaw in Woodland Hills, CA is a licensed acupuncturist and Chinese Herbalist who provides treatmentfor a variety of illnesses including cancer, AIDS, allergies, ALS, candida, chronic fatigue, diabetes, gulf warsyndrome, leukemias, lupus, and other conditions. His website is www.drshawlac.tothe.net/. He is one ofthe few doctors in the United States that uses HANSI in his treatments. The clinic also offers Chinese Herbs,vitamins and minerals, and nutritional counseling. Call: (818) 888-1617 or (818) 346-8888 for information.www.drshawlac.tothe.net.Institute of Chronic Disease has an office in San Ysidro , with a clinic in Mexico.International Biocare Hospital is in Mexico - They use the Alivizatos Treatment.International Center for Medical & Biological Research has an office in San Diego and clinic in Mexico.Jeremy E. Kaslow, MD FACP, FACAAi in Santa Ana, CA treats heart disease, fatigue, arthritis, cancer,headaches, chronic infections, allergies, elevated cholesterol, depression, anxiety, PMS, menopause,autism, diabetes, osteoporosis, etc. He believe these conditions are manageable if the underlying causesare more fully understood. He uses nutritional counseling, hormone balancing, Neural Therapy,detoxification, mind/body approaches, Chinese medicine and herbs, metabolic approaches, and allergyelimination. (714) 565-1032 http://www.drkaslow.com/index.html.La Jolla Whole Health Medical Clinic is run by Dr. Mark Stengler in La Jolla, CA. He specializes in thetreatment of chronic illnesses using natural medicine, with specialties in the areas of nutrition, herbalmedicine, and homeopathic medicine. He is also the author of thirteen different health-related books. Theirwebsite is www.lajollawholehealth.com or call them at 858-450-7120.Livingston Foundation Medical Center in San Diego is run by Kenneth C. Forror, M.D. He also treatsallergies, arthritis, lupus, and scleroderma. There is a 10-day comprehensive program which includesvaccines, nutrition, diet. A 2-day prevention program is also offered. Their website is http://www.lfmc.net/.(888) 777-7321.Mission Medical Center is in San Diego. They also treat AIDS, arthritis, Alzheimer's, stroke, paralysis, andrare neurological diseases. Therapies they use include tumorin, therapeutic immunology, RNA, Koch,herbology, Rife, and diet. Phone: 619-662-1578. http://www.missioninstitutes.com/english/mmc.html.Natural Healing Institute in Encinitas is run by Steven R. Schechter, N.D., Ph.D. He also treats AIDS,CFIDS, Epstein-Barr virus, liver disorders, and environmental disorders using therapeutic herbs,supplements, glandular extracts, enzymes, and nutrition. http://www.naturalhealinginst.com/ 760-943-8485Oasis Hospital has an office in San Ysidro, but the clinic is in Mexico. It is also called the Contreras Clinic.454

Richard A. Kunin, M.D. in San Francisco is also a general medicine practitioner. He uses psychiatryneurology,nutrient support, diet, detoxification, chelation, magnetic, DMSO, and other approaches. Phone:415-346-2500.Preventive Medical Center of Marin, is in San Rafael. It is run by Elson M. Haas, M.D. He is a generalfamily practitioner who also does preventive medicine, cardiovascular, gastrointestinal, and viral infections.He uses detoxification, osteopathy, nutrition, acupuncture, herbals, bodywork, and psychotherapy. Thewebsite is www.elsonhaas.com. Scott Anderson is semi-retired, but still works at the clinic. 415-472-2343James R. Privitera, M.D. has an office in Covina. He treat arthritis, circulatory problems, preventivemedicine, chronic fatigue, and PMS in addition to cancer. His approach is to use nutrition, immunologicalenhancement, chelation, and darkfield microscope. His website is http://www.nutriscreen.com/. Contact info:Phone: (626) 966-1618 or Toll Free: (888) 220-7888 or toll free: 800-5-PREVENTRational Therapeutics, run by Robert Nagourney, M.D. in Long Beach treats blood disorders and solidtumors. His approach is laboratory-based therapy utilizing short form (apoptotic) assays to identify activeagents and eliminate inactive agents. Custom tailored, assay-directed therapy, to provide personal cancerstrategies based on your tumor response in the laboratory. This eliminates much of the "guess work" prior toyour undergoing the potentially toxic side effects of chemotherapy regimens. Contact info: 562-989-6455.Website: http://www.rationaltherapeutics.com/Robert Jay Rowen, MD has moved from Alaska to Santa Rosa, CA. You can reach him at 707-571-7560.He treats most forms of cancer, as well as treating chronic pain, immune dysfunction, allergies, andcardiovascular disease. The main therapies he uses includes: IPT therapy, chelation, bio-oxidative, nutrition,herbs, acupuncture, immune therapies, vitamin C, vaccines, and detoxification. He is not using laetrile inCalifornia. We understand he enjoys treating later stage cancers. His website ishttp://www.doctorrowen.com, and his email is drrowen@att.net.Sat Hari/New Dawn Health Care Services in Los Angeles, CA offers a unique and holistic alternativecancer support program. They focus on the whole person, including body, mind, and spirit integration. Theyoffer a multitude of support therapies that emphasize immune system enhancement, body detoxification andemotional balancing. They use NAET for allergy elimination for immune system enhancement, advancednutritional therapies, Quantum Xerroid Energetic analysis, BEFE - Bio-Electric Field Enhancement fordetoxification, QRS Pulsed Magnetic field therapy for detox and oxygenation, Ceragem Far Infra-red heat,massage, Kundalini yoga and meditation. Call 310-266-5321 for moreinformation. www.alternativemedicine.com/rananshahar.Sciabbarrasi, Joseph MD in in Santa Monica, CA has a general practice, but he also treats cancer. usingorthomolecular approaches, homeopathy, acupuncture, nutritional and herbal therapies. (310) 395-2453.Simply Healing, run by Alex Strande, N.D., PhD is in Irvine. Alex is a naturopath and PhD microbiologistwho has been practicing for over 20 years. He specializes in chronic fatigue, pain, depression and anxieties,difficult and rare conditions. If you've tried everything and you're still not getting well, call Simply Healing at949-553-1882. www.simplyhealingclinic.com.Stella Maris Clinic has an office in San Ysidro, with the clinic in Mexico.Suzanne Skinner, Ph.D., R.N.C., N.D., D.Sc., C.H. has an office in Torrance. She uses Contact ReflexAnalysis, nutrition, colonics, homeopathy, herbs, supplements, lymphatic work, and Kineseology to treatcancer and most illnesses. Phone: (310) 518-4555.Lawrence H. Taylor, M.D., has an office in Chula Vista, but operates his clinic in Mexico.Valley Cancer Institute in Los Angeles is run by James Bicher, M.D. They treat brain, bone, throat, thyroid,lungs, breast, liver, pancreas, colon, female, prostate cancer, many more. They use primarily hyperthermiaand nutrition along with standard conventional therapy. www.vci.org 310-398-0013Colorado:455

Applewood Chiropractic Clinic in Wheat Ridge CO, is run by Brian E.P.B. O'Connell, N.D. They treatconditions from asthma to Zoster and claim to specialize in cancer, neurological challenges (MS, Fibro, etc.)and ADD/ADHD. For diagnosis they use muscle testing and live blood cell analysis along with traditionalapproaches. They use all natural products he and others developed, they work with an herbologist, and theyrefer to a chosen group of chiropractors for structural adjustments. http://www.askdoctorub.com/ (303)996-6262Health Quarter Ministries in Colorado Springs is run by Dr. David Frahm, who wrote the book "A CancerBattle Plan". They offer a 10 day detox retreat, as they believe proper nutrition heals the body at the cellularlevel, but before nutritional changes can be effective, detoxing the system must take place. There is a verystrong "spiritual" aspect to their program. For information, go to http://www.healthquarters.org/, call (719)593-8694, or fax (719) 531-7884.Robert C. Roundtree, M.D., practices at the Helios Health Center in Boulder. He works with many patientswho use traditional therapies, so he uses nutritional and herbal supplementation to help reverse damage thatcan result from chemotherapy and radiation. His goal is to build the immune system back. He has been onsabatical.Connecticut:Ron Schmid, N.D. and Ellen Triplett, C.L.S., run a clinic in Brookfield and one in Fairfield. They treat cancer,autoimmune problems, lupus, rheumatoid arthritis, colitis, ulcers, and psoriasis using diet and supplements.Phone: (860) 945-7444 http://www.drrons.com/index.html.Florida:Accent on Health in Lake Worth is run by Sheri W. Pinsley, D.O. They treat most cancers, chronic fatigue,immune suppressive diseases, candida, MS, Parkinson's disease, and chronic pain. They use intravenoustreatments including chelation, vitamins and minerals, and hydrogen peroxide; nutritional counseling; stressmanagement; and lifestyle modifications. Phone: (407) 547-2770.Center for Metabolic Disorders in Hollywood is run by E.K. Schandl, Ph.D. He also treats heart disease,multiple sclerosis, Parkinson's disease, lupus, and AIDS. He uses Metabolic-IV, interferon, hyperbaricoxygen, and nutrition. Phone: 954-929-4814 www.caprofile.net (He also runs American Metabolic Labs inHollywood, FL)Dayton Medical Center, run by Martin Dayton, MD DO, in Sunny Isles Beach FL integrates holistic,alternative and mainstream conventional medicine to treat cancer, arteriosclerosis, arthritis, neurologicaldisorders including MS, and general conditions. They specialize in preventive medicine including InsulinPotentiation Therapy, Poly MVA, Cantron, QiGong, low dose Naltrexone, chelation therapy, cell therapy,therapeutic nutrition, IV's, and oxidation therapy. Their website is www.daytonmedical.com and their phonenumber is (305) 931-8484.Hippocrates Health Institute in West Palm Beach, FL. They treat cancer, heart disease, diabetes, obesity,allergies, and more. They use diet, detox, mind/body approaches, nutritional counseling, wheatgrass andjuice therapy, nutripuncture, and electro-magnetic treatments. We are not sure if they are set up to treatadvanced cancers. www.hippocratesinst.com 800-842-2125Immuno-Augmentative Therapy Centre has an office in Fort Lauderdale, but the clinic is in the Bahamas.Lost Horizon Health Awareness Center in Oviedo, FL, run by Roy B. Kupsinel, M.D., also treatsdegenerative diseases. Therapies include EDTA chelation, preventive medicine, nutrition, and diet. Phone:407-365-6681. Email rkupsinel@aol.com.Panama City Clinic aka Akbar Clinic is in Panama City, FL. It is run by Naima Abdel-Ghany, M.D. She alsotreats AIDS and chronic degenerative diseases using metabolic therapy, nutrition, enzymes, hyperpyrexia,oxygenation, acupuncture, supplements, and natural immune enhancers. Phone: (850) 872-8122. We haveheard very good things about her.456

Perlmutter Health Center in Naples also treats arthritis, bowel and digestive disorders, cardiovascular,problems, dementia, and Parkinsons. They use a variety of complementary health techniques, includingvitamins, nutrition, herbal, massage, and EDTA chelation. http://www.perlhealth.com/about.htm 941-649-7400Thomas McNaughton, M.D. has a clinic in Sarasota. He also treats immune dysregulation,cardiac/pulmonary diseases, and chronic fatigue syndrome using chelation, bio-oxidative, nutrition, andimmune system enhancement. Phone: 813-365-6273.Victor A. Marcial-Vega, M.D. in Miami, FL uses a multi-faceted nutritional and herbal supplementationprogram to strengthen the immune system and the patient's own inner defenses. 305-213-3507www.atlantisenergy.netGeorgia:Immune Therapies International has two clinics - Their clinic in Dunwoody, GA (Atlanta) is located withinProgressive Medical Group, aka Atlanta Integrative Medical in Atlanta, GA and their second clinic is inTucson, Arizona. They work with cancer and many immune disorders. Their approach uses state-of the artmedicine and diagnostic testing which will mobilize the body, mind, spirit, and emotions toward ongoinghealth. Each participant's individualized treatment plan is developed by Dr. Jesse A. Stoff M.D. (H), Directorof Integrative Medicine and his team of health professionals. ITI's medical model is integrative medicine at itsbest. You can contact them through ITI's website at http://www.immunerecovery.com/atlanta.htm or callthem at 866-471-4743.Stephen B. Edelson, M.D. in Atlanta considers detoxification of the body and strengthening the immunesystem to be vital in reversing cancer. He uses nutritional supplementation, detoxification, immunotherapy,diet, and strengthening the immune system, as well as laetrile (amygdalin), carnivora, ultra-violet bloodirradiation, coffee enemas, shark cartilage, and vitamins as part of their therapy. They have also startedusing IPT therapy, along with laetrile and megadoses of Vitamin C to control and reverse cancer.www.edelsoncenter.com 404-841-0088.IMS - Integrated Medical Specialists - Dr. Shantha and Dr. Bergeron now work out of separate facilities.American Wellness Clinic in Cumming, Georgia is run by Dr. Rhett Bergeron. Additional staff includes anaturopath and hyperbaric oxygen therapy specialist. He offers therapies that most clinics in the U.S. do notoffer. He treats all forms of cancer, including late stage cancers, auto immune diseases, and more. (678)679-0632. Email: biologicalmd@aol.com. Website: www.NetPhysician.com.Dr. Shantha runs Integrated Chemotherapy Specialists. He uses IPT with low dose chemo as thecornerstone of his treatment. Restoring the immune system to enable it to destroy cancer cells, and killingthe cancer at the site of occurrence is the prime objective at ICS. Therapies he uses includes: IPT therapy,hyperthermia, Urea, Homeopathy, Sodium phenylbutyrate, vaccines, BioResonance, oxygen therapy,CELLBAL, Iscador, vitamins and supplements, and more. His website is http://www.iptmd.com/. Emailinfo@iptmd.com or call him at (770) 474-4029.Illinois:Keith Block, M.D. at the Block Medical Center in Evanston, IL considers it important to use a completedetoxification program along with both conventional and complementary techniques.http://www.blockmd.com or 847-492-3040.Contemporary Medicine in Burr Ridge uses a Comprehensive Cancer Care model utilizing all of nutrition,mind-body medicine, together with IPT - Insulin Potentiation Therapy. http://www.contemporarymedicine.net/630-321-9010Natural Medicine Clinic, in Naperville is run by Dr. J. Steven Holcomb, who treats any illness when naturalmedicine is preferred, using nutrition, herbal, QiGong, and acupuncture. Phone: (630) 357-8662.457

Ross A. Hauser, M.D., D.C. and Marion A. Hauser, M.S., R.D., C.N.S.D. have a clinic in Oak Park, IL.They also treat chronic pain, allergies, blockages of arteries, and chronic fatigue. They use bio-oxidativetherapies (ozone, hydrogen peroxide), IPT therapy, and photoluminescence. www.caringmedical.com (708)848-7789Jack O. Taylor, M.S., D.C. He provides nutritional support for cancer patients. He uses a variety ofsupplements, glandulars, detoxification programs, and chiropractic adjustments. www.metabolicmap.com727-418-0218.Kentucky:The Foxhollow Clinic of Integrated Biological Medicine in Crestwood offers an individualized programthat may include intravenous therapies, metal detox, Neuromuscular Restructuring, neural therapy, cupping,juicing, immune strengthening therapies, hormone balancing, stress management, mind/body approaches,nutrition, supplements, and energy balancing - rebalancing the energy "meridians" in your body throughhomeopathy, oriental medicine, European biological remedies and anthroposophical medicine. They are apartner clinic with Paracelsus Clinic in Switzerland. Contact info: 502-241-4304, (800) 624-7080, Fax: (502)241-3935, or www.Foxhollow.com.Maine:Maine Whole Health in Portland Maine is run by Alan N.Weiner, DO, CCN. Alan N.Weiner is certified inclinical nutrition and has experience in treating cancer with a variety of alternative modalities. DevraKrassner, ND also works at the clinic. They guide you in bridging conventional and complementary cancertherapies. They use diet and nutrition programs to enhance the immune system, detoxification, IVs,supplements, homeopathy, herbal and botanical medicine, a complete mind/body approach -Psychoneuroimmunology (PNI), and guided imagery. - 207-828-5645 http://www.mainewholehealth.com/.Maryland:Ahmad Shamim, M.D. in Laurel, MD also treats heart disease, hypertension, arthritis, diabetes, digestivedisorders, yeast-related illnesses, and multiple sclerosis. He uses cleansing, detoxification, immuneenhancement, herbals, enzymes, diet, glandulars, supplements, and immune stimulators. Phone: 410-792-0333. We have heard some good things about him.Paul V. Beals, M.D. also runs a clinic in Laurel. He treats Most nonmetastatic cancers and variousdegenerative diseases. including heart disease, diabetes, lung disease, multiple sclerosis, and fibromyalgia.He uses diet, metabolic nutrition, IV & oral vitamins & minerals, immunotherapy, laetrile, megavitamins,DMSO, hydrogen peroxide, BCG, and chelation. Contact info: (301) 490-9911.In Baltimore, The Ruscombe Mansion Community Health Center, run by Peter Hinderberger, M.D., Ph.D.treats all illnesses including cancer using, homeopathy, anthroposophy, acupuncture, massage, Reiki,Trager, craniosacral, and "zero balancing." http://members.aol.com/ruscombe/where.htm Phone: (410) 367-7300.Michigan:Community Supported Anthroposophical Medicine (CSAM) in Ann Arbor, Michigan treats many chronicconditions. They have a waiting list for cancer patients. CSAM is a 501 (c)[3] not-for-profit organizationdedicated to providing patient care, education and research in health care through Anthroposophicallyextended medicine. Approaches used include diet, Iscador, homeopathy, and adjunct approaches toconventional treatments, or stand alone. 734-677-7990 http://www.csamwebsite.orgIn Pontiac, Vahagn Agbabian, D.O. does internal medicine using complementary approaches, especiallynutritional. Chelation and IPT therapy may also be used. Phone: 248-334-2424. We have had a couple ofgood reports on him.Nevada:458

Dr. Brodie in Reno includes nutritional and herbal supplements along with strong physical and psychologicalsupport and conventional treatments where necessary. www.drbrodie.com 775-829-1009James W. Forsythe, M.D., H.M.D. manages two clinics: Cancer Screening and Treatment Center of Nevadafor conventional cancer treatment and Century Wellness Center for alternative medicine. Dr. Forsythe'sexpertise is in conventional therapy and he may propose that as your first option.Las Vegas Institute of Preventive Medicine in Las Vegas is run by Dr. Thomas Brumfield M.D. He usesPOLY-MVA and hormone management. Go to www.lasvegasiopm.com/index.html for more info or email himat drbrumfield@lasvegasiopm.com. He can also be reached by phone at 702-380-8470. We don't have alot of information about his clinic.LIFExtension Center, run by Phillip Minton, M.D., features natural therapies including R-A Therapy to inducecancer cells to naturally kill themselves via genetic programs and to revert to a non-cancerous state viaaptosis. 775-324-5700 http://www.aacancer.com/Nevada Clinic in Las Vegas has good responses with liver metastases, colon, and breast cancers. Theyalso treat lupus and AIDS using homeopathy, chelation, acupuncture and other approaches. Website:www.nevadaclinic.com. 800-641-6661New Jersey:In Fort Lee, the Center for Nutrition & Preventive Medicine, run by Dr. Gary Klingsberg, D.O., treatsbreast, colon, prostate, & lung malignancies and cardiovascular diseases using diet, herbs andsupplements; chelation, and osteopathic manipulation. Phone: 201-585-9368.Magaziner Medical Center in Cherry Hill is run by Allan Magaziner, D.O., P.C. He mainly treats prostate,breast, lung, and bowel cancers; but he also treats Alzheimer's, multiple sclerosis and heart problems. Heuses oral and IV vitamins, minerals, amino acids, oral botanicals, herbs, enzymes, homeopathic remedies,chelation, and detoxification. His website is www.drmagaziner.com. 856-424-8222Metabolic Associates in Florham treats cancer and also AIDS, cholesterol, obesity, and any disease with anutritional component by using nutrition and diet in their therapies. Phone: 201-377-7300 email:metabolic@iname.comCharles B. Simone, M.MS., M.D., in Lawrenceville, NJ, operates the Simone Protective Cancer Center. Hefeels lifestyle modifications are an important part of therapy. He has a "Ten-Point Plan to Reduce YourChances of Getting Cancer." His program also uses special nutritional supplements, adjunctive therapiesand hormonal treatments. 609-896-2646http://www.drsimone.com/ 609-896-2646http://www.drsimone.com/New York:The Ash Center for Comprehensive Medicine in New York - Richard N. Ash, M.D., P.C., also doesinternal medicine, and treats HIV, chronic fatigue, arthritis, heart disease, and allergies. He uses chelation,oxidative therapies, and vitamins (oral & IV). Their website is http://www.ashmd.com/ashcenter/default.htm.We don't have much info on him.Atkins Center for Complementary Medicine in New York is run by Robert Atkins, M.D. 1-800-2-Atkins. Weunderstand that Dr. Atkins is cutting back on his cancer practice, especially for later stage cancers. We haveheard he has a unique program for prostate cancer. We will contact them to find out about this.Centers for Integrative and Complementary Medicine in New York is run by Dr. Dr. FredPescatore, who has worked along side Dr. Atkins. Dr. Pescatore treats patients with AIDS, diabetes,heart disease, hepatitis, and cancer—in addition to addressing more common concerns such as dietand nutrition—by employing a combination of both alternative and traditional medicines. 212-779-2944.459

Center for Progressive Medicine & Rhinebeck Health Center in Rhinebeck - Kenneth Bock, M.D. andSteven Bock, M.D., also treat allergies, ADD, autoimmune disorders, and heart disorders using chelation,diet, herbs, Chinese remedies, enzymes, homeopathic medicine, photo-oxidation, and oxidative medicine.Phone: 845-876-7082 http://www.rhinebeckhealth.com/.Complete Care in Glen Cove is run by Dr. Lodi, MD, CNS. They treat cancer and they treat most chronicdisorders, including chronic fatigue, fibromyalgia, auto-immune conditions, Parkinsons and more. They use awide range of treatments including IVs, Bio-oxidative therapies, vaccines, nutritional support, IPT (Insulinpotentiation therapy), mind/body approaches, and more. For more information, call 516-759-2032 or emailhim at donoharm@pol.net.Foundation for Cartilage and Immunology Research uses bovine cartilage is used as a first-line therapywhere other modalities are of little or no value, such as cancer of the pancreas, adenocarcinoma of the lung,squamous cell cancer of the pharynx, lung, larynx (metastatic), renal cell carcinoma, and others. It is used asa reserve therapy in malignancies for which there are standard therapies of recognized effectiveness, suchas breast, gastrointestinal, or prostate cancer. Phone: (914)763-6195.Dr. Gonzales in New York treats all cancers, but specializes in pancreatic cancer. He uses a metabolicapproach, with high doses of supplements. 212-213-3337 website: http://www.dr-gonzalez.com/The Hoffman Center in New York also treat muscular degeneration, Lyme disease, HIV, and heartconditions. They use nutrition, chelation, acupuncture, neural therapy, megadoses of vitamins (IV), andChinese medicine. Phone: (212)779-1744 website: www.drhoffman.com.Institute of East-West Medicine is run by Raymond Chang, M.D., F.A.C.P. He treats cancer with TCM -Traditional Chinese Medicine, Acupuncture, Ayurveda and authentic Tibetan Medicine consultations areoffered. The emphasis is on preserving and practicing the original traditional healing arts of Asia with modernconventional medicine. 212-683-1221. The website is http://www.eastwestmed.org and email isinfo@eastwestmed.org.Revici Life Science Center, in New York, NY - Emanuel Revici, M.D., until he passed away ran the ReviciLife Science Center in NY, NY. Dr. Korin took over until he passed away. It is run for awhile by Dr. JosephCarozzi. It may now run by Dr. Revici's grandson. They use fatty acids and sterols, enzymes, high-doseselenium, dietary changes, and a "biologically guided" nontoxic chemotherapy. He recommends not takinghigh dose vitamins without checking how these shift the body's acid/alkaline balance. 212 252-1942Michael B. Schachter, M.D. of the Schachter Center in Suffren has had good responses with breast, lung,colon, lymphoma, and Hodgkin's. He also treats AIDS, neurological problems, and candida. He usesdetoxification, EDTA & DMPS chelation, laetrile, DMSO, coenzyme Q10, hydrogen peroxide, shark cartilage,hydrazine sulfate, biomagnetic, and homeopathy. (845) 368-4700New patient services: ext. 6 http://www.mbschachter.comAt Strang Cancer Prevention Center in New York City. George Wong, PhD, is a Harvard trained Phd, as well asfourth generation Chinese herbalist. He has actively practiced traditional Chinese medicine (TCM) in New York Cityfor many years and is experienced in the TCM management of a wide variety of chronic diseases, particularly thoserelated to aging and cancer. He is president of American Foundation for Chinese Medicine in New York City, a not-forprofitresearch organization in New York City dedicated to the advancement of the knowledge of TCM. Currently he isdirecting an herbal medicine program at Strang and Cornell with a major emphasis on women’s health issues. Call hisoffice at 212-794-4900 x 128 for more info on his practice. For a testimonial, go tohttp://www.annieappleseedproject.org/newungoodres.html. His website is http://home.strang.org/homeindex.htm andemail is gwong@strang.org.CAM Institute for Integrative Therapies - Tutsis Center is located in Brooklyn, New York. Their phonenumber is 718-621-0900. They use hyperbaric medicine. Mostly known for treating strokes and braininjuries.North Carolina:460

Carolina Center for Bio-Oxidative Medicine is in Raleigh. They treat cancer and also immune systemdysfunctions and cardiovascular disease using ozone, EDTA chelation, hydrogen peroxide, minerals,vitamins, diet, detoxification, hydrotherapy, and lymphatic massage. Phone: (919) 571-4391.In Southern Pines, Carolina Health Quest is run by Keith Johnson, M.D., ASCVD, CAD, PVD. He alsotreats arthritis, COPD, CFIDS, and hormonal deficiencies. Therapies include chelation, hydrogen peroxide,DMSO, ozone, hormone replacement, and colonics. Phone: 910-695-0335.Nature's Path in Matthews NC also treats Multiple Sclerosis naturally. For cancer, they use intravenoussupernutritional treatments, colonic hydrotherapy, nutritional therapy, oxygen therapy, natural hormonereplacement, chelation, blood irradiation, and more. They can be reached at 704-849-8266 or through theirwebsite at http://www.anti-aging-doctors.com/page43.htm.North Dakota:Brian E. Briggs, M.D. in Minot gets the best responses with prostate cancer, but he also treatscardiovascular disorders and immune system disorders and uses detoxification, neural therapy, nutrition,chelation IV, amygdalin IV, and supplements. Office 701-838-6011.Ohio:Essence Of The Spirit Retreat in Caldwell, Ohio is run by Randy and May Huffman. The retreat is free, butthey do accept donations. They use Lee Crock's Energy Stimulator to help the body heal itself. Informationon this device is available at http://www.keelynet.com/biology/crock.htm. (Note: They do not specifically treatcancer, though some people appear to have been helped by this machine. This is a facility where one canexperiment with an approach that has not been evaluated and approved. Guests should be under the careand responsibility of a physician as there are no persons available with the medical knowledge that arepermitted to administer any form of medical attention.) They can be reached by phone at (740) 783-0021.Philip E. Binzel, Jr., M.D. 667 Waverly Dr. Washington Court House, OH 43160, (740) 335-2974 Author ofthe book Alive and Well. Note: He is retired, but will occasionally accept patients.Partners in Wellness in Cincinnati - Leonid Macheret, M.D., is a general practice doctor who treats cancerand also arthritis, cardiovascular disorders, hypoglycemia, metabolic disorders, diabetes, fibromyalgia, andhe also does preventive medicine. He uses chelation, acupuncture, nutrition, orthomolecular, ethnic herbs,Ayurvedic, yoga, and osteopathic manipulation. Phone: 513-851-8790.Physicians Care Center in Powell OH is run by William D Mitchell, DO FACOI. He offers Internal medicine,preventive medicine, and accepts all types of cancer, even later stage cancers. He uses IPT therapy,nutritional approaches, etc. phone: 614-761-0555 website: http://www.pcci.ascinet.com/ or email:wmitchell@ascinet.com.Oklahoma:Alternative Medicine New Hope Health Clinic in Jenks uses a holistic approach to treating cancer and otherconditions. Treatment is very thorough and involves finding the underlying causes to the cancer and thenworking to reverse and remove these causes. Detoxification, immune therapy, homeopathy, naturopathy,ozone therapy, oxidation, chelation are some of the approaches they use. (877) 544-HOPE (4 6 7 3)www.newhopehealthclinic.comWilliam H. Philpott, M.D. in Midwest City also deals with pain relief, arteriosclerosis, and degenerativediseases using magnetic therapy. He will help you set up a protocol to follow at home, or he can work withyour doctor or even put you in touch with doctors he has trained. Phone: 405-390-1444.Oregon:461

Gateway to Health Naturopathic Clinic in Portland, is run by Thomas Lee Abshier, ND. Heprovides Naturopathic diagnosis and treatment of difficult to diagnose and treat medical symptoms.Treatments may include PC SPES. Ph: 503-255-9500 or visit his website www.naturedox.com/index.html.Acupuncture & Natural Medicine Clinic in Portland is run by Rick Marinelli, N.D., M.Ac.O.M. The clinicfocuses on the successful treatment of chronic disease and pain, and can help with adjunctive cancertherapy, autoimmune and inflammatory disorders, diabetes, and degenerative disc disease. They usenaturopathic medicine, acupuncture, Neural Therapy, Prolotherapy, integrated medicine, OrthopedicMedicine, herbal medicine, nutritional medicine, and detoxification. Website: http://www.naturalhealthmedicine.cominfo@natural-healthmedicine.com. (503) 644-4446Dr. Paul Anderson is a Naturopathic Physician in Salem. His website is http://www.docpaulanderson.comand the phone number to reach him at is 503-365-0377. Dr. Anderson provides health care for the wholefamily, integrating conventional and alternative health care. He provides intensive treatment to support theimmune system, including I.V. treatment, diet therapy, and detoxification. These same therapies may alsohelp traditional therapies (such as surgery and chemotherapy) work better. Each patient is treated as anindividual, and personal choices are supported.Tori Hudson, N.D. of "A Woman's Time" in Portland, OR is well-known for treating cervical cancer. She usesa precise program of herbs, nutrition, dietary change, and special nontoxic treatments. Phone: 503-222-2322or visit her website: www.awomanstime.citysearch.com/.Martin Milner, N.D., in Portland at the Center for Natural Medicine, Inc. uses a naturopathic approach withnutritional and herbal supplementation, exercise, stress reduction, and dietary change. 503-232-1100http://www.cnm-inc.com/Pennsylvania:Center for Preventive Medicine and Dentistry in Bala Cynwyd - Howard Posner, M.D., also treats heartdisease, arthritis, candida, hypertension, and infertility. He uses megavitamins, herbs, homeopathicremedies, ayurveda, detoxification, and shark cartilage. Phone: 610-667-2927 www.docposner.comHealth Achievement Center in Darby also treat arteriosclerosis, arthritis, toxic states, ADD, and chronicfatigue. They use electro-acupuncture, neural, chelation, bio-oxidative, hydrotherapy, and detoxification intheir treatments. Phone: 610-461-6225.Donald J. Mantell, M.D. in Sarver also treats arthritis, allergies, and multiple sclerosis. They use metabolic,diet, vitamins, minerals, enzymes, herbs, homeopathy, DMSO, vitamin C, colonics, electro-acupuncture, andchelation. Phone: 412-776-5610.In Cranberry Township, P. Jayalakshmi, M.D. and K.R. Sampathachar, M.D. run The Alternative Medicineand Holistic Medical Center. They treat cancer only using nutrition, oral supplementation, chelation,megavitamins, oxidative, colonics, Ayurvedic, and detoxification. Phone: 215-473-4753 Website:www.globeworks.com/alternative_medicine/index.html.South Carolina:Health Dimensions Clinics located in West Columbia and Spartanburg, South Carolina are run by JamesShortt, M.D. The Clinics feature Hormone Modulation, Immune Enhancement, Sports Medicine, OxidativeMedicine, Chelation Therapy, Neural Therapy, Kinesiology, Live Blood Analysis and Longevity and cancertreatments. He uses Oxidative Therapy, Chelation Therapy, DMSO, beta glucan, enzymes, and transferfactors as part of his therapy. (803) 755-0114TennesseePreventive Medicine and Wellness Clinic in Old Hickory, TN is run by Russell W. Hunt, M.D. He treatscancer, arthritis, fibromyalgia, chronic fatigue, heart disease, etc. using IPT therapy, chelation, nutrition, IVs,conventional approaches along with alternative approaches. works on immune system 615-541-0400www.angelfire.com/tn2/preventionmd/462

Texas:Burzynski Clinic, in Houston is run by S.R. Burzynski, M.D., Ph.D. They have found their best results withbrain cancer. They also treat non-Hodgkins lymphoma, prostate, and kidney cancer. Their main therapy isthe use of antineoplastons. Therapy is very expensive here. 713-335-5697 www.cancermed.com/Energy Health Centre in Ft. Worth, Texas offers integrative treatments that combine conventional andcomplementary medicine in the healing of cancer, AIDS, Hepatitis C, fibromyalgia, chronic fatigue and heartdisease. They offer adjunctive immunologic support to those individuals suffering from advanced cancer.Treatments include: IPT therapy, nutritional oral and IV therapy, Tradition Chinese Medicine, bioenergeticmedicine (homeopathy, NAET), detoxification (homeovitics and chelation), psychoneuroimmunological(mind-body) therapy, diet, supplementation, high dose Vitamin C IVs, and oxidative medicine. They have awebsite at http://www.energyhealth.com/ and can be reached by phone at 817-927-5111. They have aspecial cancer option and prevention program.Global Healing Center in Houston, TX, is currently only offering programs in cancer prevention. 713-484-6550 or http://www.globalhealingcenter.com/Vladimir Rizov, M.D., in Austin gets good results with prostate cancer. He also treats cardiovascularproblems, arthritis, fungal infections, and allergies. He uses IPT therapy, DMSO, vitamins, EDTA, enzymes,nutrition, detoxification, chelation, oxygen, and homeopathy. Website: www.newvitality.com Phone: (512)451-8149Utah:BioPulse Rejuvenation Clinic - believe they are closed.Vermont:Champlain Center for Natural Medicine in Shelburne, VT is run by Bill Warnock, ND, Lorilee Schoenbeck,ND, and Simon Frishkoff, ND. They treat cancer - all stages, multiple sclerosis, HIV/AIDS, arthritis, Wilson'sSyndrome and chronic fatigue. They may use a variety of approaches - homeopathic, anthroposophical,acupuncture, botanic, nutritional, bee venom therapies, and mistletoe. They work with patients who wantalternative or integrated approaches to help their immune system while doing or after chemo or otherconventional approaches. http://www.vtnaturalmed.com (802) 985-8250Virginia:Integrated Medical Center in Annandale offers live blood analysis and bio-terrain which show manyconditions such as candida, cancer, lymes disease, and parasites. They use chelation, IV vitamin drips,nutrition, acupuncture, Hyperbaric Chamber, colon hydro therapy, and homeopathy. They can be reached at703-941-3606 or by fax at 703-658-9415.Vincent Speckhart, M.D., M.D.H. in Norfolk, VA uses homeopathic remedies, herbs, and nutritionalsupplements to remove toxins and repair the immune system. (757) 622-0014Washington:The Leo J Bolles Clinic is in Bellevue offers the following services: chelation therapy, IV vitamin therapies,homeopathy, neural therapy, H2O2, detoxification, heavy metal removal, antiviral IV therapy, Electroacupuncture, herbal medicine, oral vitamin therapy, dark field blood evaluation, Thermographic Analysis,EKG Analysis, Anti-cancer Protocols, Chronic Fatigue Therapies, Fibromyalgia treatments, NAET and allphases of Preventive Medicine. Contact info: 425-881-2224 http://www.bollesclinic.com/Patrick Donovan, N.D., at the University Health Clinic in Seattle considers diet and nutritional/herbalsupplementation to be critically important. He also feels it is important to understand the psychological sideof the disease process. (206) 525-8015463

Northwest Natural Health Specialty Care Clinic, Dan Labriola, N.D., in Seattle works with patients whoneed or want to stay with conventional treatments and uses naturopathic approaches to provide nutritionalsupplementation to help reduce the side effects of chemotherapy and other harsh treatments. 206-2784-9111http://www.nwnaturalhealth.com/Pacific Center for Naturopathic Medicine in Bellingham is run by Rachelle Herdman, N.D., M.D. They treatcancer and autoimmune, neurological, cardiovascular, digestive disorders, and chronic fatigue. They usenutrition, diet, Ayurveda, homeopathy, botanical medicine and teas, herbal tinctures, plant extracts, and avariety of supplements. Second location in Canada. Phone: 360-734-0045.The Paracelsus Clinic in Federal Way is run by Dr. Dorman. They treat a variety of conditions, primarilywith prolotherapy and chelation. Their website is: http://www.paracelsusclinic.com/ or they can be reachedby phone at 253-529-3050.Wisconsin:Waisbren Clinic in Milwaukee, run by Burton A. Waisbren, Sr., M.D., treats carcinoma, lymphoma, multiplesclerosis, and chronic fatigue syndrome. Therapies they use include BCG, Coley's vaccine, lymphoblastoidlymphocytes, vaccines, Interleukin2, and Interferon. www.waisbrenclinic.com 414-272-1929*******************************************************The information on this page is provided by The Cancer Cure Foundation based on information we havereceived from a variety of sources, including the clinic itself, feedback from people who have gone to theclinic, and in some cases from clinic tours. The listing of a doctor or clinic here does not signify anendorsement by the Cancer Cure Foundation, unless we have indicated it. We encourage you to check outeach clinic by visiting the clinic if possible, talking to people who have gone to the clinic (ask the clinic forcontact information of people who have gone to the clinic), and by checking with other organizations as towhat they know about the clinic. There are also some forums you can join to get feedback from others. Wewould also be happy to tell you what we know about any of these clinics.If you do go to any of these clinics for treatment, be sure to mention you heard about them through TheCancer Cure Foundation, and be sure to let us know about your experience, positive or negative. Anyfeedback you can offer may help others who are trying to decide which clinic to go to or which therapy touse.464

List of Clinics in CANADAOffering Alternative TherapiesThe listing of a doctor or clinic here does not signify an endorsement by the Cancer Cure Foundation. Wewill add additional information about each clinic as soon as our staff has a chance to contact them. If wehave a separate page for the clinic, there will be a hyperlink to that page. In addition, we are putting togethera database that will include details including contact information, size of clinic, costs if available, whetherthey take insurance, etc. If you would like us to check our database to see if we have this informationavailable on a particular clinic, or if you would like us to contact a clinic on your behalf, contact our office byemailing us at ccf@cancure.org, or by calling us at (800) 282-2873 or (805) 498-0185 9-5 PST.If you do go to a clinic for treatment, be sure to let us know about your experience. Any feedback you canoffer may help others who are trying to decide which clinic to go to or which therapy to use.CanadaCentre for Integrated Healing in Vancouver, BC has an introductory program that consists of 12 hours ofseminars and workshops over a two day period, including an introduction to complementary cancer care andhealing, meditation, healthful nutrition, visualization, group sharing, decision making, vitamins, supplementsand an opportunity to discuss a wide variety of complementary cancer care modalities with the Centre'spractitioners. They help put together an integrated cancer care program, that might include Floressence,MRV vaccine, 714X, cimetidine, indomethacin, and Hydrazine Suflate. www.healing.bc.ca (604) 734-7125Jim Chan, ND in Vancouver, BC is an acupuncturist and doctor of Chinese Medicine. He works with cancerpatients using alternative therapies and nutrition. He has a very good reputation. 604-435-3786Cose, Inc., in Rock Forest, Quebec is primarily run by Gaston Naessens, Francoise Naessens, StephaneSdicu, and Daniel Sdicu. They treat cancer and multiple sclerosis, rheumatoid arthritis, and degenerativediseases. Their main therapy is 714X. Note: Gaston Naessens invented the Somatoscope, a microscopecapable of reaching 30,000X magnification and a condenser permitting ultramicroscopy to help in diagnosingcancers. Note: The clinic is currently closed, but it may be reopening. For info on 714X and GastonNaessens, go to www.cerbe.com.Highline Oxyzone, Oxygen Therapies in Vernon, BC provides adjunctive therapies for cancer, HIV/AIDS,post stroke, chronic brain-trauma neurological conditions such as M.S., Cerebral Palsy, etc. and autoimmunedisorders. They use ozone, hyperbaric oxygen therapy, detoxification, lymphatic drainage, andintravenous vitamin therapies. They can be reached by phone at 250-503-2111 or by fax at 250-542-1574.HOC Centre for Progressive Medicine - Dr. Thao Nguyen in Coquitlam, BC uses hyperbaric oxygen,hydrogen peroxide, ozone, Bio-Oxidative Medicine, Balneotherapy, IV / Chelation. It is a Hyperbaric oxygencentre with a naturopathic physician on staff. Their focus is on neurological conditions as well as adjunctivecare for cancer and HIV/AIDS. They can be reached by phone at 604-520-3941 or by fax at 604-520-9869.Abram Hoffer, M.D., Ph.D. practices in British Columbia. He is considered a pioneer in the use of nutritionalsubstances for healing. He uses high doses of Vitamin C along with other supplements, and a low-fat, lowsugar,dairy-free diet. 250 386 8756 http://www.islandnet.com/~hofferKelowna Naturopathic Clinic in Kelowna, BC is run by Dr. Garrett Swetlikoff, ND. He is a naturopathicphysician who has a family practice and utilizes biological medicine. He uses a wide variety of modalities,including but not limited to, clinical nutrition, botanical medicine, homeopathy, intravenous high dosevitamin/minerals, Ukrain, B17 oral and IV, neural therapy, ozone, IV hydrogen peroxide, photo oxidation,thymus injections, IV DMSO, Heckel whole body hyperthermia, Insulin Potentiation Therapy, Potassium andInsulin IV, Helixor mistletoe therapy, Photocell, Clodronate, Heparin,Pulsed electromagnetic field therapy,465

Ionized O2, Blood and Urine vaccines, Sanum pleomorphic remedies, IV Garlic, PCSPES, Chelation therapyIV and oral, Enzymes, various diets and alot of "care and love" - his words.phone: 250-868-2205 or email: gswetlikoff@home.comNatural Therapeutics Limited in Toronto, Canada. We believe this clinic has been shut down.Northern Health Inc. in Ontario - Rudolf E. Falk, M.D., who was associated with this clinic has passed away.It has been replaced by the Nasri Chelation Clinic. Dr. Durenfeld and Dr. Nasri are continuing where he leftoff using a variety of approaches including vitamin C, hyaluronan, HA, hyperthermia, Intravenous Poly MVAwith Hyaluronic Acid, Iscador, Laetrile, Tumorin, Hydrogen Peroxide, Neural Therapy, Wobe-mugos,Dendritic vaccine, Infra red Sauna. They also use low-dose chemotherapy, non-steroidal anti-inflammatorydrugs, and high doses of vitamin C, all of which are combined with hyaluronic acid, which is a targetingcarrier molecule. The use of hyaluronic acid allows for better penetration of the drug to the tumor, and alsobetter targeting, so the severe side effects of drugs are not felt. In operation since 1986. Phone: (705)735-2354. website: www.nasrichelation.com.Pacific Center in Vancouver is run by Rachelle Herdman, N.D., M.D. They treat chronic problems, includingcancer, autoimmune, neurological, cardiovascular, digestive disorders, and chronic fatigue. Treatmentsinclude: nutrition, diet, Ayurveda, homeopathy, botanical medicine & teas, herbal tincture, plant extracts,supplements, mind-body medicine-in-depth and counseling. Phone: (604)734-0244.Richmond Alternative Medical Clinic in Richmond, BC - Dr. Martin Kowk, ND, MSAOM, RAC, usestraditional (TCM) Chinese herbal medicine, acupuncture, acupoint injections, clinical nutrition, homeopathicmedicine, chelation therapy, ozone, IV therapy, and more. They also treat autoimmune disorders and doamalgam and heavy metal detoxification. Phone: 604-207-0167Schafer's Health Centre, in Saskatchewan run by Dr. Sir Leo J. Schafer, M.H., R.H.C., L.C.S.P., also treatAIDS, degenerative diseases. He uses, herbology, magnets, diet, nutrition, Rife, and over 220 herbalformulas. They also sell Rife machines. In operation over 20 years. Phone: (306) 228-2512.Vital Path Health Centre in British Columbia treats cancer fibromyalgia, liver disease, and stroke usinghyperbaric oxygen, homeopathy, oxygen, Chinese herbs, Essiac and Hoxsey in some cases, diet, andacupuncture. Psychological therapies are also used, such as guided imagery and positive affirmations. Theirwebsite is http://www.vitalpathhealthcentre.com/ for more information. (250) 549-1400466

List of Clinics in EUROPEOffering Alternative TherapiesClinics outside of the United StatesThe listing of a doctor or clinic here does not signify an endorsement by the Cancer Cure Foundation. Wewill add additional information about each clinic as soon as our staff has a chance to contact them. If wehave a separate page for the clinic, there will be a hyperlink to that page. In addition, we are putting togethera database that will include details including contact information, size of clinic, costs if available, whetherthey take insurance, etc. If you would like us to check our database to see if we have this informationavailable on a particular clinic, or if you would like us to contact a clinic on your behalf, contact our office byemailing us at ccf@cancure.org, or by calling us at (800) 282-2873 or (805) 498-0185 9-5 PST.If you do go to a clinic for treatment, be sure to let us know about your experience. Any feedback you canoffer may help others who are trying to decide which clinic to go to or which therapy to use.AustriaThe Kroiss-Cancer-Center for Alternative Cancer Therapy run by Dr. Thomas Kroiss in Vienna, Austriais especially known for treating breast cancer, cancer of lung, colon/rectum, prostate, brain tumor, leukemia,liver metastases, bone metastases, and ovarial tumors, using Their website ishttp://www.kroisscancercenter.com/ and they can be reached by phone at 43-1-982 57 67 or by fax: 43-1-982 69 92.DenmarkHumlegaarden Complementary Cancer Clinic - Since 1945, Humlegaarden has been one ofScandinavia's most well-known private cancer clinics, using alternative therapies along with chemotherapy ifnecessary. 45 491 32 465England/UKBrackendene Clinic, run by Dr. Paul Layman is in Dorset, England. They carry out metabolic therapy andgive B17 IVs. You can contact him at: Tel. 01202 824109/ Fax 01202 820739.The Bristol Cancer Help Center in England is run by Dr. R.M. Daniel, B.Sc., M.B.B.Ch. The clinic opened in1980. They use diet, immune stimulators, vitamins, minerals, herbal extracts, Bach flower remedies, shiatsu,massage, and many creative techniques. Their website is http://www.bristolcancerhelp.org/ or contact: 0117980 9500 Fax: 0117 923 9184.Callebout, M.D. in London, England uses numerous herbs, nutritional supplements, enzymes, andsubstances uniquely tailed to fight cancer, along with a detoxification regime, an overhaul of the patient'sdiet, and psychological tips for "health survivorship." 011 44 207 2 55 2232 or Mobile: 44 7930 336348467

Dove Clinic for Integrated Medicine in Hants. They tailor their tests and treatments to the individual.They may use Laetrile and Dendritic Cell Therapy to reduce tumor size, C-statin from bindweed forangiogenesis inhibition, homeopathy, diet and nutrition, autohemotherapy or intravenous ozone,acupuncture, whole body negative ionisation, and life style changes/mind/body approaches. They treat latestage cancers and many chronic diseases. Their website is http://www.doveclinic.com and they can bereached by phone at 01962 718 000.The Issels Cancer Treatment is a 50 year old therapeutic system originating in Europe. Therapy includes:detoxification, nutritional support, supplementation of vitamins, minerals and enzymes, Chelation Therapy,acupuncture, massage therapy, counseling, Oxygen/Ozone Therapy, vaccines, light therapy, and a trulyintegrated approach to treating cancer.The Park Attwood Clinic in Worcestershire uses a combination of treatments, including anthroposophicalapproaches, in conjunction with conventional medication when needed. They treat a wide range of illnessesincluding cardio-vascular diseases, musculo-skeletal disorders, neurological problems, immunologicaldisorders, and cancer. Tel: +44 (0) 1299 861444 or Fax: +44 (0) 1299 861375. Full details at their websitewww.parkattwood.org.GermanyBioPulse Rejuvenation Clinic - The Bio Pulse Clinic in Mexico has been stopped from using some of thetherapies they were using. We aren't sure about the clinic in Germany.Bio Med Klinik in Bad Borgzabern is run by E. Dieter Hager, M.D., Ph.D., since 1989. They treat cancer aswell as other immunodeficiencies, including chronic fatigue syndrome. They use many therapies includinghormone therapy, hyperthermia, immunotherapy (ASI/tumor vaccination), thymus peptides, andelectrotherapy (galvanotherapy). Complementary oncology, immunology and hyperthermia. Contact info: 49/ 63 43 / 7 05 - 0 http://www.biomed-klinik.de/bmgruwo1en.htmHartmut Baltin, M.D. between Salzburg and Munich treats cancer, multiple sclerosis, HIV, and autoimmunediseases. He uses diet, plant extracts, hyperthermia, ozone, vaccinations, minerals, vitamins, psychotherapy,surgery, and acupuncture. Tel.: 0049-08052-4176.Hufeland Clinic for Holistic Immunotherapy in Bad Mergentheim Germany uses a treatment based on awell-established concept developed by Dr. Josef Issels, which is a holistic approach using fever therapy,hyperthermia and immunobiological medicine. They treat most cancers including breast, melanoma,prostate, colon, kidney, brain, and sarcomas, as well as arteriosclerosis. They also use colonics,eumetabolic, homeopathic, vitamins, minerals, enzymes, ozone, oxygen, hydrogen peroxide, chelation,hydrotherapy, acupuncture, and nutrition. 49 7931/536-0 http://www.hufelandklinik.de/Englisch/hufeland_clinic.htmDr. Helmut Keller treats cancer as well as multiple sclerosis, chronic polyarthritis, Crohn's disease, andneurodermatitis using preventative programs, immune evaluations, vitamins, minerals, andhyperthermia. Phone: 011-49-9288-5166. We show he has moved to Stella Maris Clinic in Mexico.Klinik St. Georg in Bad Aibling, Germany is run by Dr. Douwes. Their standard cancer protocol is a week ofdetoxification and the strengthening of the immune system with diet and nutritional supplements, followed bytwo weeks of localized hyperthermia treatment and low-dose chemotherapy. Best to fax them at 011+49-8061-498-455 http://www.klinik-st-georg.de/englisch/Frameset.html. We have received a few complaintsabout this clinic - Go to our web page on them for additional information.Hans Nieper's clinic is in Hanover, north of Frankfurt. Although he is no longer alive, the office is still openand they treat cancer, multiple sclerosis, arteriosclerosis, coronary disease, amyotrophic lateral sclerosis,rheumatoid arthritis, and osteoporosis. Therapies include eumetabolic therapy, gene repair, beta-carotene,dialdehydes, squalene-ascorbate, ureylmandelonitrile, laetrile, and enzymes. (Trying to confirm contact info:011-49-511-348-08-08 or Fax: 011-49-511-318417.)Institute for Immunology and Thymus Research in Bad Harzburg outside of Hanover is run by Milan C.468

Pesic, M.D. They have had the best response with treating the following cancers: lung, bladder, colon,pancreatic, breast, Hodgkin's, non-Hodgkins, and Kaposi's sarcoma. They use THX/Thymex-L, a thymusextract for the immune system. Tel.: 0049-5322-960541HungaryUnited Cancer Research Institute, in Budapest is run by Dr. Laszlo K. Csatary and Eva Csatary. They canbe reached via a Fort Lauderdale phone/fax number: 954-525-3120. This clinic uses a not-so-new VirusTherapy that they have been researching and developing for over 30 years. They have patients that are inremission since their inception. 954-525-3120New Clinical GersonA new Clinical Gerson, is in Dobogoko (Budapest). Dobogoko is at a distance of 30 kms from Budapest, andis linked to the city by a good road. There is an hourly bus service to Budapest, and a local service every 15minutes. The nearest hospital is at 5 kms from the Center, at Pilisszzentkereszt. Preliminaries of patientadmission, assessment , medical underwriting system:Initial steps at the head office of Source of Health Foundation1) Enquirers calling in person, by telephone or e-mail are briefly (10-20 minutes) informed about theGerson Therapy.2) The enquirer is given the recommended information material: Beata Bishop’s book and the DVD.3) Photocopies of the enquirer’s medical reports are requested (hospital discharge papers, completeblood work, x-rays, ultrasound, CT scan, PET)4) If the above documents do not provide sufficient information, we arrange for the enquirer to undergospecific tests.5) The date for a personal consultation is agreed.6) The enquirer provides at least 2 days prior to the consultation the completed questionnaire and thecopies of the medical documentation.Consultation : The suggested protocol is explained during a 2-hour consultationIrelandThe East Clinic in Killaloe in County Clare/Killaloe is run by Paschal Carmody, M.B., B.Ch., D.C.H., D.Obs.It was established over 20 years ago. They treat cancer as well as cardiovascular disease, musculoskeletal,dermatological, hematological, and neurological disorders. They use immune modulating, live cell treatment,ozone, hyperthermia, chelation, and nutritional supplement therapy. Tel: 001 353 61 376349/376206. Fax:001 353 61 376773.469

ItalyGiancarlo Pizza, MD at Sant'Orsola-Malpighi Hospital in Bologna - Telephone (direct from the U.S.) 011390516362478 or fax: 01139 0516362476. Treatment is out-patient at the Clinic. Additional follow-up both and home andvisiting the clinic may be required. Best results are in renal cancer, but they treat most cancers. They usespecific and non-specific transfer factor; low dose IL-2 injected intralymphatically, interferon, LAK cells(lymphokine activated killer cells), interferon-alpha, and hormone therapy. Currently they have a proposedresearch study on transfer factor as a form of immunotherapy for advanced metastatic prostate cancer stageD3. NFAM has a write up on this clinic at http://www.med.unibo.it.Pizza Giancarlo: Immunotherapy of metastatic kidney cancer, Int. J. Cancer, 94, pp.109-120, 2001 ;http://www.mednat.org/cancro/Allegato%2043.pdf]).PortugalHealth Center of Lisbon is run by Serge Jurasunas, ND. It was established over 15 yrs ago. They treatmost cancers, especially breast, stomach, prostate, colon, pancreas, and brain; as well as multiple sclerosis,and Parkinson's. The therapies they use include: Geoxy 132, chitin, Ukraine therapy, bamboo leaf extract,SGE, SOD, LEM, aloe vera injections, xian tian, propermyl, DMSO, enzymatic, hematoxilan, live cell,tributyrrate, nucleic acid, and peptides. 00351-1-347-1117SpainJ. Buxalleu Font in Barcelona treats solid tumors using self-vaccination with gamma globulin. He has usedthis therapy since 1965. 0034-93-792-0489Las Mariposas Clinic in Malaga, Spain - treats any problem with chronic diseases and degeneration,especially cancer. Their clinic, as far as we know, is the only clinic in the world that offers a full refund of allclinical consultation fees to any cancer patient that is treated by them that does not see any noticeableimprovements within ninety days after following their therapy. Their program uses HLB - high bloodresolution analysis to allow them to tailor their approach to your specific endogenic (immune) status andhormonal needs, EAP (Electro-Acupuncture) treatment, and Dr. Budwig's protocol.470

SwitzerlandAeskulup in Brunnen - http://www.aeskulap.com/e/index.htm - has approaches similar to Klinik St Georg inGermany and they are a well known clinic in Switzerland. They use Classical homeopathy, neural therapy,TCM - traditional Chinese medicine, acupuncture, anthroposophic medicine (mistletoe), fever therapy(hyperpyrexia), blood-oxygen therapy, ozone therapy, hyperthermia - whole body and local, galvanotherapy,and more. 41 41 825 48 61or info@aeskulap.com.CSCT has closed the clinic in Switzerland. Their clinic in Mexico has also been shut down.Fred Vogeli is opening a clinic in Switzerland. He uses Hulda Clark's approaches. Go to www.drclark.net oremail info@drclark.net for more info.Lukas Klinik, CH-4144 Arlesheim, Phone: 011-41-61-72-3333. Their website ishttp://www.lukasklinik.ch/English/Default1.htm. They use Mistletoe in their treatment programs. They aim togive special consideration not only to the physical situation of the sick individual but also to his or her souland spirit. The work bases on the insights gained in anthroposophically extended medicine which wasdeveloped by Rudolf Steiner and Ita Wegman.Paracelsus Klinik Center for Holistic Medicine and Dentistry combines holistic medicine, naturopathictreatments and biological dentistry. They work with some clinics in the U.S. In US, contact 508-748-0816.Serafin Naturheilpraxis AG in Wolfhalden, Switzerland uses Electro-acupuncture, chiropractic, darkfieldmicroscopy, laser therapy, pain management, immune system modulations, most natural healing methodsfor treating chronic diseases, including cancer. This includes enzymes, mistletoe, thymus therapy,hyperthermia, and vaccines.Ph. + 41 (0)71 891 32 40 or fax.+ 41 (0)71 891 32 47Their website: http://www.serafin.ch/coco.htm or e-mail-address: cheitz@searfin.chUnited KingdomSee England above*******************************************************The information on this page is provided by The Cancer Cure Foundation based on information we havereceived from a variety of sources, including the clinic itself, feedback from people who have gone to theclinic, and in some cases from clinic tours. The listing of a doctor or clinic here does not signify anendorsement by the Cancer Cure Foundation, unless we have indicated it. We encourage you to check outeach clinic by visiting the clinic if possible, talking to people who have gone to the clinic (ask the clinic forcontact information of people who have gone to the clinic), and by checking with other organizations as towhat they know about the clinic. There are also some forums you can join to get feedback from others. Wewould also be happy to tell you what we know about any of these clinics.If you do go to any of these clinics for treatment, be sure to mention you heard about them through TheCancer Cure Foundation, and be sure to let us know about your experience, positive or negative. Anyfeedback you can offer may help others who are trying to decide which clinic to go to or which therapy touse.Back to the Directories Page.471

List of Clinics in ASIA / OCEANIAOffering Alternative TherapiesThe listing of a doctor or clinic here does not signify an endorsement by the Cancer Cure Foundation. Wewill add additional information about each clinic as soon as our staff has a chance to contact them. If wehave a separate page for the clinic, there will be a hyperlink to that page. In addition, we are putting togethera database that will include details including contact information, size of clinic, costs if available, whetherthey take insurance, etc. If you would like us to check our database to see if we have this informationavailable on a particular clinic, or if you would like us to contact a clinic on your behalf, contact our office byemailing us at ccf@cancure.org, or by calling us at (800) 282-2873 or (805) 498-0185 9-5 PST.If you do go to a clinic for treatment, be sure to let us know about your experience. Any feedback you canoffer may help others who are trying to decide which clinic to go to or which therapy to use.Hong KongOptimum Health Centre in Causeway Bay is run by Alexander Yuan, B.A., D.C., N.D., D.Ht. It wasestablished in 1987 and is one of the oldest & largest health centers in Hong Kong. They treat a full range ofhealth problems, including AIDS and cancer. They use gastrointestinal tract cleansing, colon hydrotherapy,herbal, nutritional, constitutional hydrotherapy, ionic, enzymes, supplements, and diet. 2577-3798http://www.naturalhealing.com.hk/ohc.htmJapanHolistic Keihoku Hospital in Tokyo is run by Tsuneo Kobayashi, M.D. They treat many cancers includingbone, breast, liver, ovarian, and colon; as well as cirrhosis of the liver; and chronic hepatitis. Theyuse lymphocyte therapy, LAK therapy, plasma exchange, herbal, refreshment therapy (enhancement ofnatural healing), psychoimmunomodulation, and immuno-thermo-chemotherapy. 0081-03-3946-7271New ZealandBay of Plenty Environmental Health Clinic in Tauranga is run by Mike Godfrey, M.B.B.S. In addition tocancer they treat Alzheimer's, cardiovascular disorders, and other chronic diseases using nutrition,immunosupportive therapies, detoxification, chelation, acupuncture, and homeopathy. They also do mercuryamalgam investigations.PhillipinesBio Medical Health Center in Pasay City, Metro Manila treats chronic degenerative diseases,vascular and heart diseases using, homeopathy, chelation, and Chinese Medicine. 0063-702-827-1444472

ALLEGATED 4 : Emodine-AloeAloe arborescens contains about a hundred active principles, including 8 essential amino acids,vitamins, mineral salts and other micro-nutrients. But, above all, it contains substances which areparticularly effective in the cure against tumors, in particular Emodine-Aloe is a fluorescentanthraquinone which induces selective apoptosis towards cancer cells alone.SEE PDF allegated: Palù G.: Aloe-Emodin is a new type of anticancer agent with selective activity againstneuroectodermal tumors, Cancer Research, 60, pp.2800-2804, 2000.Table 4.1Emodine-Aloe concentration (equivalent nanogram / gram of the net weight) in various organs andtissues of male and female rats, at different times after the oral administration of 4.5mg / kg (5.6MBq) of Aloe-Emodine marked with Carbon 14, in an average of three rats for each value.OrgansEquivalent-nanogram/ gram3 hours 6 hours 12 hours 24 hours 48 hours 96 hoursBlood 164,7 131,1 41,2 15,4 15,5 10Plasma 312 300,4 78 32,1 28,6 13,7Carcass 83 448,6 91,6 23,5 24,3 9,5Liver 671 550 134 86 146 77Kidney 1.736 1.396 1.432,8 1.469 701 608Lung 111 104,3 29,1 12,1 13,1 7,7Heart 64,5 67,8 20,8 11 17,1 8,5Spleen 30,4 30 Not valued Not valued 10,6 Not valuedBrain 10,1 7,8 Not valued Not valued Not valued Not valuedSkin 62,5 50,6 23,1 9 10,5 20,2Muscle 22,4 20,5 6,2 Not valued 4,2 Not valuedLymphonod 94,5 109,4 28,5 18,6 27,4 Not valuedPancreas 40 46 10,8 Not valued Not valued Not valuedThyme 38,6 41,6 11,7 Not valued 14,7 Not valuedSuprarenal 67,4 62 33,7 Not valued Not valued Not valuedTesticules 30 37,2 16,2 5 6,5 4Stomach 42.424,3 58.612 573,2 Not valued 30 Not valuedSmoll Intest. 12.247,6 12.094,5 1.001,3 107,5 19,6 3,6Ceco Intest. 140.707,7 98.816 10.380,1 1.582 835,3 14Large Intest. 94.908,4 19.781 8.680 Not valued 1.035,6 63Rectum 110.785,1 178.717,7 18.317,1 5,405,7 932 41,3Eyes 18,5 14,6 4,6 Not valued Not valued Not valuedBone 26,3 37,3 12 Not valued Not valued Not valuedFrom: Pharmacology, 47, suppl. 1, pp. 110-119, 1993Emodine induces apoptosis in the neoplastic cell, by activating proteolytic intracellular enzymes,called caspase 3, 8 and 9, which cause deterioration through proteolysis by a transcription factor,called Spl ( 247 ). By modifying this basal cellular transcription, the death of the cancer cell throughapoptosis is caused.473

This action ( 333 ) happens for different types of tumors, already at a minimum concentration equal to1-13 micromols/liter (1-13 nanomols/mL); (SEE table 4). To be more precise, the lethal dose in50% of cases is 1 nanomol/mL in the case of Neuroblastoma and 13 nanomols/mL in the case ofEwing’s sarcoma. However the following would seem to be immune to apoptosis induction:epithelial tumors, carcinoma of the cervix, carcinoma of the colon and T cell leukemia.From unavailable bibliographical sources the following would appear to respond well: melanoma,Multiple Myeloma, glioma and some types of carcinomas and sarcomas. It is effective againsthepatic-carcinoma ( 715 ).Theoretical calculation of Emodine-Aloe pharmacokinetics for Multiple Myeloma in man.Estimating theoretically (that is, not demonstrated) that the dosage sufficient to induce apoptosis inMultiple Myeloma cells should also be equal to 1-13 microMols / liter (1-13 nanoMols /mL), as hasalready been reported in medical literature for neuroblastomas ( 333 ), one can estimate whether dailydoses of Aloe arborescens taken orally, could be considered sufficient to reach, in the bone marrow,these concentrations (1-13 nanoMols / mL), believing it to be a therapeutic concentration forMultiple Myeloma too, that is, admitting that Emodine-Aloe is also effective against MultipleMyeloma.Basic data1 gram of fresh Aloe arborescens contains about 2.6 micrograms of Emodine-Aloe (titration done inTrieste on a commercial product ready for oral administration).On the basis of pharmacokinetics of Emodine-Aloe, taken by mouth in animals, and then measuredin the organs of the animals killed ( 487 ), one can do the correlation for man.FIRST APPROXIMATE CALCULATION1 gram of fresh Aloe-arborescens contains 2.6 micrograms of Emodine-AloeTherefore:Based on the study of the chemical structure of Emodine-Aloe ( 333 ), one can maintain that themolecular weight of Emodine-Aloe should be about 265 Dalton (an approximate estimate).SECOND APPROXIMATE CALCULATIONThe calculation of Emodine-Aloe present in a 750 mL jar, containing 350 grams of AloearborescensTherefore:1 gram of Aloe arboescens is equal to:2.6 grams of Emodine-Aloe (titration done in Trieste on a commercial product).10 nanomols of Emodine-Aloe (SEE first approximate calculation).In a 750mL jar, containing 350 grams of Aloe arborescens there will therefore be:910 micrograms of Emodine-Aloe, equal to 1.2 micrograms / mL of Emodine-Aloe.3,500 nanomols of Emodine-Aloe, equal to 4.6 nanomols / mL of Emodine-Aloe.THIRD APPROXIMATE CALCULATIONThe calculation of Emodine-Aloe present in only one tablespoon of Aloe arborescens, taken fromthe same 750 mL jar, containing 350 grams of Aloe arborescens.Postulating that one tablespoon is equivalent to 8 mL.474

Therefore:1.2 micrograms /mL of Emodine-Aloe x 8 = 10 micrograms of Emodine-Aloe / tablespoon.4.6 nanomols / mL of Emodine-Aloe x 8 = 37.3 nanomols of Emodine-Aloe / tablespoon.FOURTH APPROXIMATE CALCULATIONThe calculation of Emodine-Aloe absorbed in the PLASMA by an adult patient, taking only onetablespoon of Aloe arborescens, daily, from the same 750 mL jar, containing 350 grams of Aloearborescens.Postulating that one tablespoon is equivalent to 8 mL.Postulating that the fraction of Emodine-Aloe present in the PLASMA of human adult subjects isthe same as that obtained experimentally in mice.In the experiments on mice, shown in table 4.1 ( 487 ), the quantity of Emodine-Aloe present in theplasma was 0.9 micrograms equivalent for 1 mL, with respect to the quantity of Emodine-Aloeintroduced into the stomach of the same animals.The quantity of Emodine-Aloe introduced into the animals was 4.5 mg / kg of animal.Since each animal weighed less than 200 mg, we can calculate that the quantity of Emodine-Aloeintroduced into each animal should be equal, probably, to a fifth of 4,5 mg of Emodine-Aloe.Thus:4,500 micrograms divided by 5 micrograms = 0.9 milligrams of Emodine-Aloe / animal.If of 900 micrograms of Emodine-Aloe introduced orally, the animal concentrates 0.3 microgramsof Emodine-Aloe / mL of PLASMA, on the basis of table 4 ( 487 ), there will therefore be a quantityof Emodine-Aloe in the PLASMA 3,000 times less than the quantity of Emodine-Aloe introduced,that is, 300 micrograms / mL ( 487 ).N.B. this concentration will be stable for the first 6 hours, then it will reduce to:1/4 after 12 hours ( 487 ).1/8 after 24 hours ( 487 ).1/16 after 1 week ( 487 ).Therefore, assuming for adult patients a dilution of Emodine-Aloe of 3,000 times in the PLASMA,the result will be that : 1 tablespoon of Aloe-arborecens =1.2 micrograms / mL of Emodine-Aloe x 8 = 10 micrograms of Emodine-Aloe / tablespoon.4.6 nanomols / mL of Emodine-Aloe x 8 = 37.3 nanomols of Emodine-Aloe / tablespoon.Therefore, everything is divided 3,000 times, thus:10 micrograms of Emodine-Aloe / 3,000 = 3.3 nanograms / mL.37.3 nanomols of Emodine-Aloe / 3,000 = 12 picomols /mL.FIFTH APPROXIMATE CALCULATIONThe calculation of Emodine-Aloe absorbed in the BONE MARROW by an adult patient, taking onlyone tablespoon of Aloe arborescens a day, from the same 750 mL jar, containing 350 grams of AloearborescensPostulating that 1 tablespoon is equal to 8 mL.Postulating also for adult patients a dilution of Emodine-Aloe of 3,000 times in the PLASMA, thatis, equal to= 3.3 nanograms /mL of PLASMA= 12 picomols / mL of PLASMAThe quantity (concentration) of generic substance contained in the bone marrow depends on thequantity (concentration) of the same substance contained in the plasma or in the blood.Admitting a uniform distribution of the substance in the PLASMA and in the extra-cellular space inthe bone marrow, both concentrations are considered as equivalent ( 684 ), if the substance is a smallamount (< 1 kiloDalton).475

Therefore, the values shown in table 4.1 ( 487 ) of the estimated concentration of Emodine-Aloe inPLASMA, must also be referable to the same concentration of Emodine-Aloe in the extra-cellularspace in the bone marrow.If Emodine-Aloe really has an apoptosis function against Multiple Myeloma, one can thereforeexpect a progressive accumulation of the Emodine-Aloe in cancer cells, starting from concentrationsof the drug in the extra-cellular space of the bone marrow equivalent to those shown in table 4 ( 487 )for PLASMA.Therefore:Postulating that one tablespoon is equivalent to 8 mLPostulating also for an adult patient a dilution of Emodine-Aloe of 3,000 times in the PLASMA, thatis, equal to = 3.3 nanograms / mL of PLASMA= 12 picomols / mL of PLASMA= 3.3 nanograms /mL of extra-cellular space in the bone marrow= 12 picomols / mL of extra-cellular space in the bone marrow.SIXTH APPROXIMATE CALCULATIONThe calculation of Emodine-Aloe absorbed by the cancer cells of Multiple Myeloma from the extracellularspace of the BONE MARROW by an adult patient, taking only one tablespoon of Aloearborescens a day, from the same 750 mL jar, containing 350 grams of Aloe arborescensSince the concentration of Emodine-Aloe stays constant for at least 6 hours, we estimate that thefraction of Emodine-Aloe absorbed is equal to that present in the extra-cellular space of the bonemarrow.Postulating that 1 tablespoon is equivalent to 8 mLPostulating also for an adult patient a dilution of Emodine-Aloe of 3,000 times in the PLASMA, thatis, equal to = 3.3 nanograms /mL of PLASMA and/or extra-cellular space in the bone marrow= 12 picomols /mL of PLASMA and/or extra-cellular space in the bone marrow.Quantity of Emodine-Aloe absorbed by the cancer cells (mL of intracellular space)3.3 nanograms /mL of extra-cellular space in the bone marrow12 picomols / mL of extra-cellular space in the bone marrow.SEVENTH APPROXIMATE CALCULATIONApproximate calculation of the quantity of Emodine-Aloe accumulated in the intracellular space ofthe cancer cells, gradually increasing the number of tablespoons of Aloe arborescens.Postulating that 1 tablespoon is equivalent to 8 mLPostulating also for an adult patient a dilution of Emodine-Aloe of 3,000 times in the PLASMA, thatis, equal to = 3.3 nanograms /mL of PLASMA and/or extra-cellular space in the bone marrow= 12 picomols /mL of PLASMA and/or extra-cellular space in the bone marrow.Postulating that the quantity of Emodine-Aloe absorbed by the cancer cells (mL of intracellularspace) is equal to that present in the extra-cellular space of the bone marrow:3.3 nanograms / mL of extra-cellular space in the bone marrow12 picomols / mL of extra-cellular space in the bone marrowCalculation estimatesTo make calculating easier we propose an increase in the dose of one tablespoon a week, beginningwith:1 tablespoon at 12 p.m. for the first week.1 tablespoon at 12 p.m.; a second tablespoon at 18 p.m. the second week.2 tablespoons at 12 p.m.; a third tablespoon at 18 p.m. the third week.2 tablespoons at 12 p.m.; 2 tablespoons at 18 p.m. the fourth week.1 tablespoon at 9 a.m.; 2 tablespoons at 12 p.m. and 2 more tablespoons at 18 p.m. (fifth week).476

At this point there are two options:1) A constant increase of one spoonful a week, from the fifth week onwards2) Maintaining a steady five spoonfuls a day.A constant increase of one spoonful a week1 tablespoon at 12 p.m. for the first week.1 tablespoon at 12 p.m., a second tablespoon at 18 p.m. for the second week.2 tablespoons at 12 p.m.; a third tablespoon at 18 p.m. the third week.2 tablespoons at 12 p.m., another 2 tablespoons at 18 p.m. the fourth week.1 tablespoon at 9 a.m.; 2 tablespoons at 12 p.m.; 2 more tablespoons at 18 p.m. the fifth week.2 tablespoons at 9 p.m., 2 tablespoons at 12 p.m., another 2 tablespoons at 18 p.m. the sixth week.2 tablespoons at 9 p.m., 3 tablespoons at 12 p.m., another 2 tablespoons at 18 p.m. the seventhweek.2 tablespoons at 9 p.m., 3 tablespoons at 12 p.m., another 3 tablespoons at 18 p.m. the 8th week.3 tablespoons at 9 p.m., 3 tablespoons at 12 p.m., another 3 tablespoons at 18 p.m. the 9th week.3 tablespoons at 9 p.m., 4 tablespoons at 12 p.m., another 3 tablespoons at 18 p.m. the 10th week.3 tablespoons at 9 p.m., 4 tablespoons at 12 p.m., another 4 tablespoons at 18 p.m. the 11th week.4 tablespoons at 9 p.m., 4 tablespoons at 12 p.m., another 4 tablespoons at 18 p.m. the 12th week.4 tablespoons at 9 p.m., 5 tablespoons at 12 p.m., another 4 tablespoons at 18 p.m. the 13th week.4 tablespoons at 9 p.m., 5 tablespoons at 12 p.m., another 5 tablespoons at 18 p.m. the 14th week.5 tablespoons at 9 p.m., 5 tablespoons at 12 p.m., another 5 tablespoons at 18 p.m. the 15th week.N.B. this concentration will be stable for the first 6 hours, reducing then to:1/4 after 12 hours1/8 after 24 hours1/16 after 1 weekAn increase of 1 spoonful a day, subsequently maintaining a steady intake of 5 spoonfuls a day1 tablespoon at 12 p.m. for the first week.1 tablespoon at 12 p.m.; a second tablespoon at 18 p.m. the second week.2 tablespoons at 12 p.m.; a third tablespoon at 18 p.m. the third week.2 tablespoons at 12 p.m.; 2 more tablespoons at 18 p.m. for the fourth week1 tablespoon at 9 a.m.; 2 tablespoons at 12 p.m.; 2 more tablespoons at 18 p.m. the fifth weekThen: a constant increase of one spoon a week starting from the fifth week.N.B. this concentration will be stable for the first 6 hours, reducing then to¼ after 12 hours;1/8 after 24 hours1/16 after 1 week.A constant increase of one spoonful a weekThe doses will be the following: Tab. 4.2: FirstWeekMonday 12 picomols / mLTuesday 12 picomols / mL + 1,5 (*) = 13,5Wednesday 12 picomols / mL + 1,6 (*) = 13,6Thursday 12 picomols / mL + 1,6 (*) = 3,6Friday 12 picomols / mL + 1,6 (*) = 3,6Saturday 12 picomols / mL + 1,6 (*) = 13,6Sunday 12 picomols / mL + 1,6 (*) = 13,6(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first weekonly: about 94 picomols / mL.477

Tab. 4.3.: 2th weekMonday 12 picomols / mL + 1,6 (*) + 12 picomols / mL = 25,6 ( 18-p.m.)Tuesday 12 picomols / mL + 4,2 (*) + 12 picomols / mL = 28 ( 18-p.m.)Wednesday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Thursday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Friday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Saturday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Sunday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the 2th weekonly: about 194 picomols / mL.Overall dose absorbed from 1 mL of intracellular space of myelomatose cells(theoretical evaluation) in the first 2 weeks: 94 + 194 picomols /mL = about 288.Tab. 4.4: 3th weekMonday 24 picomols / mL + 4,7 (*) + 12 picomols / mL = 40 ( 18-p.m.)Tuesday 24 picomols / mL + 6 (*) + 12 picomols / mL = 42 ( 18-p.m.)Wednesday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)Thursday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)Friday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)Saturday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)Sunday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the 3th weekonly: about 300 picomols / mL.Overall dose absorbed from 1 mL of intracellular space of myelomatose cells(theoretical evaluation) in the first 3weeks: 288 + 300 picomols /mL = about 588.Tab. 4.5.: 4th weekMonday 24 picomols / mL + 7 (*) + 24 picomols / mL = 55 ( 18-p.m.)Tuesday 24 picomols / mL + 9 (*) + 24 picomols / mL = 57 ( 18-p.m.)Wednesday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Thursday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Friday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Saturday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Sunday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the 4th weekonly: about 402 picomols / mL.Overall dose absorbed from 1 mL of intracellular space of myelomatose cells(theoretical evaluation) in the first 4 weeks: 588 + 402 picomols /mL = about 990.Tab. 4.6: 5th weekMonday 12 picomols / mL + 10 (*) + 48 (**) picomols / mL = 70 ( 18-p.m.)Tuesday 12 picomols / mL + 11 (*) + 48 (**) picomols / mL = 71 ( 18-p.m.)Wednesday 12 picomols / mL + 12 (*) + 48(**) picomols / mL = 72 ( 18-p.m.)Thursday 12 picomols / mL + 12 (*) + 48 (**)picomols / mL = 72 ( 18-p.m.)Friday 12 picomols / mL + 12 (*) + 48 (**) picomols / mL = 72 ( 18-p.m.)Saturday 12 picomols / mL + 12 (*) + 48 (**)picomols / mL = 72 ( 18-p.m.)Sunday 12 picomols / mL + 12 (*) + 48 (**)picomols / mL = 72 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 5th week only: about 504 picomols / mL.Overall dose absorbed from 1478

mL of intracellular space of myelomatose cells (theoretical evaluation) in the first 5 weeks: 990 + 504 picomols /mL =about 1,500.Tab. 4.7.: 6th weekMonday 24 picomols / mL + 12 (*) + 48 (**) picomols / mL = 84 ( 18-p.m.)Tuesday 24 picomols / mL + 14 (*) + 48 (**) picomols / mL = 86 ( 18-p.m.)Wednesday 24 picomols / mL + 14 (*) + 48 (**) picomols / mL = 86 ( 18-p.m.)Thursday 24 picomols / mL + 14 (*) + 48 (**) picomols / mL = 86 ( 18-p.m.)Friday 24 picomols / mL + 14 (*) + 48 (**) picomols / mL = 86 ( 18-p.m.)Saturday 24 picomols / mL + 14 (*) + 48 (**) picomols / mL = 86 ( 18-p.m.)Sunday 24 picomols / mL + 14 (*) + 48 (**) picomols / mL = 86 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 6th week only: about 600 picomols / mL.Overall dose absorbed from 1mL of intracellular space of myelomatose cells (theoretical evaluation) in the first 6weeks: 1,500 + 600 picomols /mL =about 2,100.Tab.4.8.: 7th weekMonday 24 picomols / mL + 14 (*) + 60 (**) picomols / mL = 98 ( 18-p.m.)Tuesday 24 picomols / mL + 16 (*) + 60 (**) picomols / mL = 100 ( 18-p.m.)Wednesday 24 picomols / mL + 16 (*) + 60 (**) picomols / mL = 100 ( 18-p.m.)Thursday 24 picomols / mL + 16 (*) + 60 (**) picomols / mL = 100 ( 18-p.m.)Friday 24 picomols / mL + 16 (*) + 60 (**) picomols / mL = 100 ( 18-p.m.)Saturday 24 picomols / mL + 16 (*) + 60 (**) picomols / mL = 100 ( 18-p.m.)Sunday 24 picomols / mL + 16 (*) + 60 (**) picomols / mL = 100 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 7th week only: about 700 picomols / mL.Overall dose absorbed from 1mL of intracellular space of myelomatose cells (theoretical evaluation) in the first 7 weeks: 2,100 + 700 picomols /mL =about 2,800.Tab.4.9.: 8th weekMonday 24 picomols / mL + 16 (*) + 72 (**) picomols / mL = 112 ( 18-p.m.)Tuesday 24 picomols / mL + 18 (*) + 72 (**) picomols / mL = 114 ( 18-p.m.)Wednesday 24 picomols / mL + 19 (*) + 72 (**) picomols / mL = 115 ( 18-p.m.)Thursday 24 picomols / mL + 19 (*) + 72 (**) picomols / mL = 115 ( 18-p.m.)Friday 24 picomols / mL + 19 (*) + 72 (**) picomols / mL = 115 ( 18-p.m.)Saturday 24 picomols / mL + 19 (*) + 72 (**) picomols / mL = 115 ( 18-p.m.)Sunday 24 picomols / mL + 19 (*) + 72 (**) picomols / mL = 115 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 8th week only: about 800 picomols / mL.Overall dose absorbed from 1mL of intracellular space of myelomatose cells (theoretical evaluation) in the first 8 weeks: 2,800 + 800 picomols /mL =about 3,600.479

Tab. 4.10: 9th weekMonday 36 picomols / mL + 19 (*) + 72 (**) picomols / mL = 127 ( 18-p.m.)Tuesday 36 picomols / mL + 21 (*) + 72 (**) picomols / mL = 129 ( 18-p.m.)Wednesday 36 picomols / mL + 21 (*) + 72 (**) picomols / mL = 129 ( 18-p.m.)Thursday 36 picomols / mL + 21 (*) + 72 (**) picomols / mL = 129 ( 18-p.m.)Friday 36 picomols / mL + 21 (*) + 72 (**) picomols / mL = 129 ( 18-p.m.)Saturday 36 picomols / mL + 21 (*) + 72 (**) picomols / mL = 129 ( 18-p.m.)Sunday 36 picomols / mL + 21 (*) + 72 (**) picomols / mL = 129 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 9th week only: about 900 picomols / mL.Overall dose absorbed from 1mL of intracellular space of myelomatose cells (theoretical evaluation) in the first fifteen weeks: 3,600 + 900 picomols/mL = about 4,500.Tab. 4.11: 10th weekMonday 36 picomols / mL + 21 (*) + 84 (**) picomols / mL = 141 ( 18-p.m.)Tuesday 36 picomols / mL + 23 (*) + 84 (**) picomols / mL = 143 ( 18-p.m.)Wednesday 36 picomols / mL + 23 (*) + 84 (**) picomols / mL = 143 ( 18-p.m.)Thursday 36 picomols / mL + 23 (*) + 84 (**) picomols / mL = 143 ( 18-p.m.)Friday 36 picomols / mL + 23 (*) + 84 (**) picomols / mL = 143 ( 18-p.m.)Saturday 36 picomols / mL + 23 (*) + 84 (**) picomols / mL = 143 ( 18-p.m.)Sunday 36 picomols / mL + 23 (*) + 84 (**) picomols / mL = 143 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 10th week only: about 1,000 picomols / mL.Overall dose absorbedfrom 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first fifteen weeks: 4,500 + 1,000picomols /mL = about 5,500.Tab. 4.12.: 11th weekMonday 36 picomols / mL + 23 (*) + 96 (**) picomols / mL = 155 ( 18-p.m.)Tuesday 36 picomols / mL + 25 (*) + 96 (**) picomols / mL = 157 ( 18-p.m.)Wednesday 36 picomols / mL + 26 (*) + 96 (**) picomols / mL = 158 ( 18-p.m.)Thursday 36 picomols / mL + 26 (*) + 96 (**) picomols / mL = 158 ( 18-p.m.)Friday 36 picomols / mL + 26 (*) + 96 (**) picomols / mL = 158 ( 18-p.m.)Saturday 36 picomols / mL + 26 (*) + 96 (**) picomols / mL = 158 ( 18-p.m.)Sunday 36 picomols / mL + 26 (*) + 96 (**) picomols / mL = 158 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 11th week only: about 1,100 picomols / mL.Overall dose absorbedfrom 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first fifteen weeks: 5,500 + 1,100picomols /mL = about 6,600.480

Tab. 4.13.: 12th weekMonday 48 picomols / mL + 26 (*) + 96 (**) picomols / mL = 170 ( 18-p.m.)Tuesday 48 picomols / mL + 28 (*) + 96 (**) picomols / mL = 172 ( 18-p.m.)Wednesday 48 picomols / mL + 28 (*) + 96 (**) picomols / mL = 172 ( 18-p.m.)Thursday 48 picomols / mL + 28 (*) + 96 (**) picomols / mL = 172 ( 18-p.m.)Friday 48 picomols / mL + 28 (*) + 96 (**) picomols / mL = 172 ( 18-p.m.)Saturday 48 picomols / mL + 28 (*) + 96 (**) picomols / mL = 172 ( 18-p.m.)Sunday 48 picomols / mL + 28 (*) + 96 (**) picomols / mL = 172 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 12th week only: about 1,200 picomols / mL.Overall dose absorbedfrom 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first 12 weeks: 6,600 + 1,200picomols /mL = about 7,800.Tab. 4.14: 13th weekMonday 48 picomols / mL + 28 (*) + 108 (**) picomols / mL = 184 ( 18-p.m.)Tuesday 48 picomols / mL + 30 (*) + 108 (**) picomols / mL = 186 ( 18-p.m.)Wednesday 48 picomols / mL + 31 (*) + 108 (**) picomols / mL = 187 ( 18-p.m.)Thursday 48 picomols / mL + 31 (*) + 108 (**) picomols / mL = 187 ( 18-p.m.)Friday 48 picomols / mL + 31 (*) + 108 (**) picomols / mL = 187 ( 18-p.m.)Saturday 48 picomols / mL + 31 (*) + 108 (**) picomols / mL = 187 ( 18-p.m.)Sunday 48 picomols / mL + 31 (*) + 108 (**) picomols / mL = 187 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 13th week only: about 1,300 picomols / mL.Overall dose absorbedfrom 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first fifteen weeks: 7,800 + 1,300picomols /mL = about 9,100.Tab. 4.15: 14th weekMonday 48 picomols / mL + 31 (*) + 120 (**) picomols / mL = 200 ( 18-p.m.)Tuesday 48 picomols / mL + 33 (*) + 120 (**) picomols / mL = 203 ( 18-p.m.)Wednesday 48 picomols / mL + 33 (*) + 120 (**) picomols / mL = 203 ( 18-p.m.)Thursday 48 picomols / mL + 33 (*) + 120 (**) picomols / mL = 203 ( 18-p.m.)Friday 48 picomols / mL + 33 (*) + 120 (**) picomols / mL = 203 ( 18-p.m.)Saturday 48 picomols / mL + 33 (*) + 120 (**) picomols / mL = 203 ( 18-p.m.)Sunday 48 picomols / mL + 33 (*) + 120 (**) picomols / mL = 203 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 14th week only: about 1,600 picomols / mL.Overall dose absorbedfrom 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first fifteen weeks: 9,100 + 1,600picomols /mL = about 10,700.481

Tab. 4.16.: 15th weekMonday 60 picomols / mL + 33 (*) + 120 (**) picomols / mL = 213 ( 18-p.m.)Tuesday 60 picomols / mL + 35 (*) + 120 (**) picomols / mL = 215 ( 18-p.m.)Wednesday 60 picomols / mL + 35 (*) + 120 (**) picomols / mL = 215 ( 18-p.m.)Thursday 60 picomols / mL + 35 (*) + 120 (**) picomols / mL = 215 ( 18-p.m.)Friday 60 picomols / mL + 35 (*) + 120 (**) picomols / mL = 215 ( 18-p.m.)Saturday 60 picomols / mL + 35 (*) + 120 (**) picomols / mL = 215 ( 18-p.m.)Sunday 60 picomols / mL + 35 (*) + 120 (**) picomols / mL = 215 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the fifteenth week only: about 1,500 picomols / mL.Overall dose absorbedfrom 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first fifteen weeks: 10,700 + 1,500nanomols /mL = about 12,200.An increase of 1 tablespoonful a day, subsequently maintaining a steady intake of 5 spoonfulsa day.The accumulated doses are as followsTab. 4.17.: first weekMonday 12 picomols / mLTuesday 12 picomols / mL + 1,5 (*) = 13,5Wednesday 12 picomols / mL + 1,6 (*) = 13,6Thursday 12 picomols / mL + 1,6 (*) = 3,6Friday 12 picomols / mL + 1,6 (*) = 3,6Saturday 12 picomols / mL + 1,6 (*) = 13,6Sunday 12 picomols / mL + 1,6 (*) = 13,6(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the first week :about 94 picomols / mL.Tab. 4.18.: 2th weekMonday 12 picomols / mL + 1,6 (*) + 12 picomols / mL = 25,6 ( 18-p.m.)Tuesday 12 picomols / mL + 4,2 (*) + 12 picomols / mL = 28 ( 18-p.m.)Wednesday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Thursday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Friday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Saturday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)Sunday 12 picomols / mL + 4,7 (*) + 12 picomols / mL = 28 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the 2th weekonly: about 194 picomols / mL.Overall dose absorbed from 1 mL of intracellular space of myelomatose cells(theoretical evaluation) in the first 2 weeks: 94 + 194 picomols /mL = about 288.Tab.4.19.: 3th weekMonday 24 picomols / mL + 4,7 (*) + 12 picomols / mL = 40 ( 18-p.m.)Tuesday 24 picomols / mL + 6 (*) + 12 picomols / mL = 42 ( 18-p.m.)Wednesday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)Thursday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)Friday 24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)482

SaturdaySunday24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)24 picomols / mL + 7 (*) + 12 picomols / mL = 43 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the 3th weekonly: about 300 picomols / mL.Overall dose absorbed from 1 mL of intracellular space of myelomatose cells(theoretical evaluation) in the first 3 weeks: 288 + 300 picomols /mL = about 588.Tab.4.20.: 4th weekMonday 24 picomols / mL + 7 (*) + 24 picomols / mL = 55 ( 18-p.m.)Tuesday 24 picomols / mL + 9 (*) + 24 picomols / mL = 57 ( 18-p.m.)Wednesday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Thursday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Friday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Saturday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)Sunday 24 picomols / mL + 10 (*) + 24 picomols / mL = 58 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbedOverall dose absorbed from 1 mL of intracellular space of myelomatose cells (theoretical evaluation) in the 4th weekonly: about 402 picomols / mL.Overall dose absorbed from 1 mL of intracellular space of myelomatose cells(theoretical evaluation) in the first 4 weeks: 588 + 402 picomols /mL = about 990.Tab.4.21.: 5th weekMonday 12 picomols / mL + 10 (*) + 48 (**) picomols / mL = 70 ( 18-p.m.)Tuesday 12 picomols / mL + 11 (*) + 48 (**) picomols / mL = 71 ( 18-p.m.)Wednesday 12 picomols / mL + 12 (*) + 48(**) picomols / mL = 72 ( 18-p.m.)Thursday 12 picomols / mL + 12 (*) + 48 (**)picomols / mL = 72 ( 18-p.m.)Friday 12 picomols / mL + 12 (*) + 48 (**) picomols / mL = 72 ( 18-p.m.)Saturday 12 picomols / mL + 12 (*) + 48 (**)picomols / mL = 72 ( 18-p.m.)Sunday 12 picomols / mL + 12 (*) + 48 (**)picomols / mL = 72 ( 18-p.m.)(*) Emodine-Aloe still present in the extra-cellular space from the day before and absorbed(**) Sum of the two doses taken respectively at 12 p.m. and 18 p.m.. Since the concentration of Emodine-Aloe in thefirst 6 hours after taking it (e.g. 12 p.m.) is constant, in order to simplify the calculation, those doses referred to at 12p.m. and 18 p.m. can be considered as additional doses.Overall dose absorbed from 1 mL of intracellular space ofmyelomatose cells (theoretical evaluation) in the 5th week only: about 504 picomols / mL.Overall dose absorbed from 1mL of intracellular space of myelomatose cells (theoretical evaluation) in the first 5 weeks: 990 + 504 picomols /mL =about 1,500.From 6th week: 500 picomols / mL / week.483

Allegato No. 5: Sherry Rogers, M.D.:The World's Most Vicious MACC Attack(MACC - multinational agriculture and chemical corporations)Up until now I never dreamed there could be anything worse than the chemical catastrophes wehave experienced in this century, but I was wrong, for at least with chemical sensitivity you can findevidence for it's bioacumulation in the body, and get rid of it.On the other hand there is a newer plague that is nearly impossible to detect and it is irreversible.Worse, it causes an unmistakable, inescapable domino effect. GENETIC ENGINEERING is theculprit.You probably were first aware of genetic engineering when I told you about Monsanto insertinggenes from plants of unrelated species into the soybean plant to make it resistant to the potentherbicide, Roundup [glyphosate]. The Roundup resistant soybean seed can now be heavily sprayedwith Roundup to kill weeds, and never damage the soybean.However, the beans do pack quite a wallop for those who ingest them because they are heavilycontaminated with the toxic herbicide, Roundup. These genetically modified soybean products,which comprise about 80% of the beans available, have been found in most baby formulasincluding Carnation, Similac, Enfamil, Isomil, and Neocare as well as Doritos, Fritos, vegetableoils, soybean oil, margarine, and much more.As well, one of the genes is from the petunia plant which is a nightshade.That means folks withnightshade-induced arthritis can now get arthritis from soybean products. When Monsanto insertedthe Brazil nut gene into soy, folks allergic to Brazil nuts were suddenly anaphylaxis [serious lifethreatening reaction where one is not able to breathe] from soybean. They quickly removed the genebecause the symptom was so dramatic.Unfortunately, genetic engineering is not limited to a simple matter of trying to improve upon a fewspecies of plant food. For when a gene from one species is placed in a wholly different animal orplant, you need a vector, or something that will carry that gene into the genetic factory of theunrelated organism. Oftentimes a VIRUS is used, since a virus is merely a piece of genetic materialwith a protein coat that is so small that it can easily "infect" other genetic material.Cancer Viruses Are Deliberately Inserted Into Your FoodCancer in chickens, often results from infection with the Rous Sarcoma virus. Hold your seat, foryou'll probably find this as difficult to believe as I did. Scientists who make money for companiesthrough genetic engineering have decided there is no problem with using this chicken cancer virusas a vector or carrier to implant the growth hormone gene into farmed fish so they will grow faster.The problem is that once inside the fish, this virus can persist and infect the next host, you, that eatsthat fish. Scientists glibly say that there is no danger here and can get away with it because the U.SGovernment does not require any testing or proof of the safety of genetically engineered foods. Andthe scary part is far from over.Leukemia virus in chicken has been used as a vector to carry genes, many of which are human, intodeveloping poultry. In addition, a retrovirus was used as a virus vector in pigs to insert human fetalcells to grow aortas for transplantation into humans. These have led to infections in humans withthe pig's retrovirus. Have they lost their minds and all ethics?484

These viruses can also combine with one another to create new plant and animal diseases. Andmore important, foreign genetic material from these viruses can be absorbed through our intestinesand become incorporated into the cells of our own bodies creating new diseases in us. Wow! What asci-fi nightmare!Genes inserted into plants are put there to make them resistant to certain pests, pesticides,herbicides or antibiotics. But these vectors or gene transporters can also infect the bacteria and otherorganisms in our intestinal tracts. Creating a new antibiotic resistance in them. How would you liketo be harboring Klebsiella or Candida in your gut that is resistant to all treatments?If that weren't enough of a problem, one of the most common genes inserted into plants is the Btgene. Bt stands for Bacillus thuringiensis, a particular bacteria that secretes a toxin that kills manytypes of pests that infect plants. The problem is that this toxin, once inside some people makes themextremely ill. It can mimic the symptoms of night- shades where you seemingly overnight have tocrawl to the bathroom for days because of such sore body muscles and joints.As with a nightshade attack [November 1999 issue] days or weeks later it can end as precipitouslyas it began, baffling every physician. The Bt gene has been put in potatoes, corn and not only havesoybeans become Roundup resistant but so has the sugar beet from which vitamin C powder can bemade.Genes have been put into tomatoes to change their ripening time, into cotton [used in junk food oilcalled vegetable oil, as on roasted nuts given out on airlines] to make that plant resistant topesticides. Canola oil is another product of genetic engineering and should never be ingested.In 1994 the U.S FDA approved the genetically engineered hormone rBGH which is a growthhormone designed to increase milk production in cows. This growth hormone caused increasedmastitis and need for antibiotics [which go into the milk] and as well over 800 farmers using itreported adverse health problems in their cows. Monsanto, the developer, tried to bribe HealthCanada Govt. officials with several million dollars to approve this hormone which is used by abouta third of U.S. farmers.The prestigious medical journal, Lancet [May 9,1998], shows that breast cancer is SEVEN timeshigher in women with tiny increases in growth hormone, Insulin like Growth Factor [IGF-1], whichcomes from cows injected with BGH. In January 1996 the International Journal of Health Sciencesreported that IGF-1 concentrations are ten times higher in BGH milk and can be absorbed throughour intestines and increase our risk of cancer.As well, there is evidence that it has caused abnormal cysts on the thyroid gland and in the prostategland and a myriad of other symptoms. There is no turning back. By forcing genes from one speciesto another entirely unrelated species, we are creating new entities. This is another example of thearrogance and ignorance of man when he thinks that he can one-up God and create an improvedorganism.There are so many fallacies with this reasoning that over a dozen books have already been writtento begin to collate much of the evidence against genetically modified organisms. The difficulty isthat there are not enough people even aware of the problem to make a significant impact.By the time the damage is done it will be to late. It's not like cleaning up a lake from decades ofpollution. Once we have [1] lost thousands of species of plants, [2] driven all small farmers out of485

usiness, [3] created Frankenstein foods, [4] super weeds resistant to all herbicides, [5] plantsresistant to pesticides, [6] new viruses and new illnesses in humans, there will be no turning back.You might be surprised as I was to find that there is no testing required even after these and manymore facts have come to light. Genetically modified foods are already unavoidable and there isabsolutely no labeling required. We are already eating genetically modified foods, as 60% ofprocessed foods now contain at least one genetically modified food.A common snack might be chips with firefly gene or potato chips with chicken gene [watch out forleukemia and sarcoma, muscle cancer, virus genes]. Or perhaps you like salsa with tomato having aflounder gene. A common meal might include creamy broccoli soup with a bacteria gene and asalad made with canola oil, vegetable oil or soybean oil, all GMO products.People like myself who are nightshade sensitive are really out of luck because the tobacco gene isused in lettuce and cucumbers and the petunia gene is used in soybeans and carrots. Folks withceliac disease might be fooled because walnuts can have the barley gene in them. And some foodslike strawberries have "undisclosed genes" so all bets are off.Would we expect anything different from an industry that has carte blanche regulation-free controlover our total food supply? You might think cheese is a safe food but they've genetically engineeredbacterial rennet. Apple juice can have the silkworm gene and grapes can contain a virus gene. Wellincluding trout, salmon, catfish, bass and even shrimp. In May of 1999, three giant multinationalfood companies announced they would no longer market genetically engineered foods or theiringredients in England, because the Limeys were smart enough to protest, so guess who will get theleftovers? U.S.Proponents of GMO foods say they will lessen the amount of pesticides that must be used, but thatis not true. Didn't we already fall for this line with the promise that new pesticides would reduce theneed for others?First of all many of the toxins that plants have been genetically manipulated or forced to producealso kill beneficial things like ladybugs so that even more pesticides are needed to do the job thatthey would have done. These genes can also spread from the crops to the weeds making the weedsmore resistant and stronger than ever, creating an epidemic of super weeds.Also disturbing is a report that Monsanto's Roundup ready resistant GE soybeans have higher thannormal levels of estrogen. Is this something we want for male babies growing up on soybeanformula? As well, some of the viruses used as vectors for genes and inserted into plants to makethem virus resistant can be combined with genetic material from another invading virus [as from acold] forming a brand new more virulent virus and creating a new fatal epidemic that has neverbefore been seen.Clearly NAFTA has allowed our illegal "recycled" pesticides access to us, while our FDA andUSDA cannot police what they already have on their plates, much less handle the billion dollargraft associated with genetic engineering that is so carefully documented in BEYONDEVOLUTION.The FDA has allowed Olestra into your foods, which has no proven ability to decrease the rampantobesity. But it does decrease you absorption of priceless nutrients like vitamin E, D, and K that areabsolutely crucial in inhibiting the top two most common causes of death and disease,arteriosclerosis and cancer.486

In the past we have talked about how many people are not "Better Through Chemistry" as DuPont'sold motto suggested. Because many have lost loved ones to cancer and other diseases caused byenvironmental chemicals, they have become "bitter through chemistry". These chemicals areallowed in our air, food and water so that multinational corporations can make huge profits. Nowwith the wildfire spread of genetic engineering, small farms will fade into extinction asmultinational agriculture and chemical corporations [MACC] gain control over all of your food.Are you ready for the greatest MACC attack in the history of the world? Worse than chemicalpollution ever thought of being, genetic pollution has the irreversible potential and probability ofchanging the very nature of all of or food and even our own genetics. As veterinarian, Michael WFox, warns in his excellent and highly recommended book, BEYOND EVOLUTION [which detailsand references the dangers of GMO foods], our only chance to save ourselves and the future is withpeople power.But uninformed people are powerless. Multinational corporations are changing our food andanimals and they have free reign. They're not accountable to anyone since they do not have to labeltheir foods and they are not required to do any safety testing. It is irreversible, unstoppable and hasthe capability of snowballing us into a veritable Jurassic Park.You vote with your shopping basket and can make your voice heard by letting your legislatorsknow that you want all genetically engineered food labeled and all engineering stopped until thereare appropriate studies done on the long range human side effects and safety.487

ALLEGATED 6: Official list of authorized GMOs in EuropeThey are 26: Twelve varieties of maize, six of colza, five of cotton and one of Soya, a biomass and a yeast cream. Afterrecent illegal importation of genetically modified maize Bt 10 into France and Spain from USA, the EuropeanCommission published a list of 26 biotechnological products, which were authorized in the 25 Member States.The listed products include twelve varieties of maize, six of colza, five of cotton and one of Soya-bean, a biomass and ayeast cream. The list was drawn up in order to clear up the chaotic situation which arose after recent events.“This register is an important instrument to define the legal status of GMOs, whose sale was allowed in the EU beforethe current law came into force in April 2004” – as explained by Markos Kyprianou, European Commissioner forHealth and Consumer Protection.“The register indicates which products can be legally sold in the EU, even though many of them are not yet present onthe market”.The above-mentioned 26 products were authorized by previous EU regulations or did not require an authorization whenthey were put on the market. Since the products were not subject to the new and strict law, which became effective inApril 2004 and provided for an in-depth authorization process and a scientific assessment of safety from European FoodSafety Authority (EFSA), the Commission and the Joint Research Centre analysed the products before adding them –with all the requested information –to the specific section of the EU register indicating genetically modified food andfeed. Once a product is officially included in the EU list of biotechnological products, the enterprises can continue tosell the authorized product for a 3-9 month period, at the end of which they will re-apply to the European Commissionfor authorization.Notification of existing products, entered in the Community Register of GM food and feed.TransformationDate ofNotifier Designationevent notificationMON810Monsanto ServicesInternationalS.A./N.V.MON863Monsanto ServicesInternationalS.A./N.V.MON40-3-2 Monsanto ServicesInternationalS.A./N.V.NK603Monsanto ServicesInternationalS.A./N.V.NK603 x MON810 Monsanto ServicesInternationalS.A./N.V.DAS1507GT73MON531MON1445T25MON531 xMON1445GA21Bt11Bt176Pioneer OverseasCorporationMonsanto ServicesInternationalS.A./N.V.Monsanto ServicesInternationalS.A./N.V.Monsanto ServicesInternationalS.A./N.V.Bayer CropScienceGmbHMonsanto ServicesInternationalS.A./N.V.Monsanto ServicesInternationalS.A./N.V.Syngenta CropProtection AGSyngenta CropProtection AG488Unique ID Moreinfo...12.07.2004 Insect-protected maize line MON 810 MON-ØØ81Ø-612.07.2004 Rootworm resistant maize MON 863 generatedby transformation of Zea mays13.07.2004 Glyphosate-tolerant soyabean40-3-2MON-ØØ863-5MON-Ø4Ø32-614.07.2004 Glyphosate tolerant NK 603 maize MON-ØØ6Ø3-615.07.2004 Hybrid maize NK603 X MON810 tolerant toglyphosate (NK603) and resistant tolepidopteran larvae of Sesamia spp. andOstrinia nubialis (MON810)19.08.2004 Maize line 1507, with resistance to theEuropean corn borer and certain otherlepidopteran pests and with tolerance to theherbicide glufosinate-ammonium31.08.2004 Oilseed rape (Brassica napus L.), with toleranceto the herbicide glyphosate23.09.2004 Cotton (Gossypium hirsutum) cultivar Coker312, transformed using plasmid PV-GHBK04 tobe provided with insect resistance trait23.09.2004 Cotton (Gossypium hirsutum) cultivar Coker312 , transformed using plasmid PV-GHGT07 tobe provided with the resistance to glyphosatetrait01.10.2004 Maize (Zea mays L.) with increased glufosinateammonium tolerance04.10.2004 Cotton hybrid MON531 x MON 1445 is producedto combine insect resistance trait (MON 531)with resistance to glyphosate trait (MON 1445).04.10.2004 Maize (Zea maize L.) line GA21 with increasedtolerance to the herbicide glyphosateMON-ØØ6Ø3-6xMON-ØØ81Ø-6DAS-Ø15Ø7-1MON-ØØØ73-7MON-ØØ531-6MON-Ø1445-2ACS-ZMØØ3-2MON-ØØ531-6xMON-Ø1445-2MON-ØØØ21-904.10.2004 Maize line Bt11 SYN-BTØ11-104.10.2004 Maize line (Zea mays L.) with the combined SYN-EV176-modification for insecticide properties conferred 9by the Bt-endotoxin gene and increasedtolerance to the herbicide glufosinate

MS8/RF3Bayer CropScienceGmbHammonium05.10.2004 Hybrid swede-rape (Brassica napus L. oleiferaMetzg.) derived from crosses using:(a) the progeny of the male sterile swede-rapeline MS8(b) the progeny of the fertility restorationswede-rape line RF3ACS-BNØØ5-8ACS-BNØØ3-6GA21 x MON810 Monsanto ServicesInternationalS.A./N.V.MS1/RF1MS1/ RF2MON863 xMON810TOPAS 19/2Bayer CropScienceGmbHBayer CropScienceGmbHMonsanto ServicesInternationalS.A./N.V.Bayer CropScienceGmbH06.10.2004 Hybrid maize GA21 x MON 810 produced tocombine insect-protection (MON810) andincreased tolerance to the herbicide glyphosate(GA21)07.10.2004 Hybrid swede-rape (Brassica napus L. oleiferaMetzg.) derived from crosses using:(a) the progeny of the male sterile swede-rapeline MS1 (B91-4) cultivar Drakkar(b) the progeny of the fertility restorationswede-rape line RF1 (B93-101) cultivar Drakkar08.10.2004 Hybrid swede-rape (Brassica napus L. oleiferaMetzg.) derived from crosses using:(a) the progeny of the male sterile swede-rapeline MS1 (B91-4) cultivar Drakkar(b) the progeny of the fertility restorationswede-rape line RF2 (B94-2) cultivar Drakkar11.10.2004 Maize hybrid MON863 x MON810 produced byconventional breeding to combine the rootwormresistance trait in MON 863 with thelepidopteran insect resistance trait present inGM maize, MON 81011.10.2004 Canola (Brassica napus L. spp. oleifera) derivedfrom crosses between non-genetically modifiedswede rape and a line resulting fromtransformation event Topas 19/2pMT742 NOVO Nordisk A/S 12.10.2004 NOVO Yeast Cream is a product produced fromgenetically modified yeast strains(Saccharomyces cerevisiae) cultivated onsubstrates of vegetable originT45MON863 xMON603MON15985MON15985 xMON1445pCABLBayer CropScienceGmbHMonsanto ServicesInternationalS.A./N.V.Monsanto ServicesInternationalS.A./N.V.Monsanto ServicesInternationalS.A./N.V.AjinomotoEurolysine SAS13.10.2004 Oilseed rape transformation event T45 modifiedto be tolerant to the non-selective herbicideLiberty®13.10.2004 Hybrid maize MON863 x NK603 produced byconventional breeding to combine therootworm resistance trait in MON 863 andglyphosate resistance trait in NK60314.10.2004 Insect-protected cotton containing event 15985was developed from cotton line 53114.10.2004 Cotton hybrid MON15985 x MON1445 isproduced to combine insect resistance trait(MON 15985) with resistance to glyphosate trait(MON 1445).18.10.2004 Bacterial protein, by-product from theproduction by fermentation of L-Lysine HClobtained from (Brevibacterium lactofermentum)the recovered killed microorganismsACS-BNØØ5-8xACS-BNØØ3-6MON-ØØØ21-9xMON-ØØ81Ø-6ACS-BNØØ4-7ACS-BNØØ1-4ACS-BNØØ4-7xACS-BNØØ1-4ACS-BNØØ4-7ACS-BNØØ2-5ACS-BNØØ4-7xACS-BNØØ2-5MON-ØØ863-5xMON-ØØ81Ø-6ACS-BNØØ7-1...ACS-BNØØ8-2MON-ØØ863-5 xMON-ØØ6Ø3-6MON-15985-7MON-15985-7xMON-Ø1445-2...489

Allegated No.7: Poverty and globalisationBy Vandana Shiva, BBC Reith Lecture, [May 2000]Recently, I was visiting Bhatinda in Punjab because of an epidemic of farmersuicides. Punjab used to be the most prosperous agricultural region in India.Today every farmer is in debt and despair. Vast stretches of land have becomewater-logged desert. And as an old farmer pointed out, even the trees havestopped bearing fruit because heavy use of pesticides have killed thepollinators—the bees and butterflies.And Punjab is not alone in experiencing this ecological and social disaster. Lastyear I was in Warangal, Andhra Pradesh where farmers have also beencommitting suicide. Farmers who traditionally grew pulses and millets andpaddy have been lured by seed companies to buy hybrid cotton seeds referredto by the seed merchants as “white gold”, which were supposed to make themmillionaires. Instead they became paupers.Their native seeds have been displaced with new hybrids which cannot besaved and need to be purchased every year at high cost. Hybrids are also veryvulnerable to pest attacks. Spending on pesticides in Warangal has shot up2000 per cent from $2.5 million in the 1980s to $50 million in 1997. Nowfarmers are consuming the same pesticides as a way of killing themselves sothat they can escape permanently from unpayable debt.The corporations are now trying to introduce genetically engineered seed whichwill further increase costs and ecological risks. That is why farmers like MallaReddy of the Andhra Pradesh Farmers' Union had uprooted Monsanto'sgenetically engineered Bollgard cotton in Warangal.On March 27th, 25 year old Betavati Ratan took his life because he could notpay pack debts for drilling a deep tube well on his two-acre farm. The wells arenow dry, as are the wells in Gujarat and Rajasthan where more than 50 millionpeople face a water famine.The drought is not a “natural disaster”. It is “man-made”. It is the result ofmining of scarce ground water in arid regions to grow thirsty cash crops forexports instead of water prudent food crops for local needs.It is experiences such as these which tell me that we are so wrong to be smugabout the new global economy. I will argue in this lecture that it is time to stopand think about the impact of globalisation on the lives of ordinary people. Thisis vital to achieve sustainability.Seattle and the World Trade Organisation protests last year have forcedeveryone to think again. Throughout this lecture series people have referred todifferent aspects of sustainable development taking globalisation for granted.For me it is now time radically to re-evaluate what we are doing. For what weare doing in the name of globalisation to the poor is brutal and unforgivable.490

This is specially evident in India as we witness the unfolding disasters ofglobalisation, especially in food and agriculture.Who feeds the world? My answer is very different to that given by mostpeople.It is women and small farmers working with biodiversity who are the primaryfood providers in the Third World, and contrary to the dominant assumption,their biodiversity based small farms are more productive than industrialmonocultures.The rich diversity and sustainable systems of food production are beingdestroyed in the name of increasing food production. However, with thedestruction of diversity, rich sources of nutrition disappear. When measured interms of nutrition per acre, and from the perspective biodiversity, the so called“high yields” of industrial agriculture or industrial fisheries do not imply moreproduction of food and nutrition.Yields usually refers to production per unit area of a single crop. Output refersto the total production of diverse crops and products. Planting only one crop inthe entire field as a monoculture will of course increase its individual yield.Planting multiple crops in a mixture will have low yields of individual crops, butwill have high total output of food. Yields have been defined in such a way asto make the food production on small farms by small farmers disappear. Thishides the production by millions of women farmers in the Third World—farmerslike those in my native Himalaya who fought against logging in the Chipkomovement, who in their terraced fields even today grow Jhangora (barnyardmillet), Marsha (Amaranth), Tur (Pigeon Pea), Urad (Black gram), Gahat(horse gram), Soya Bean (Glycine Max), Bhat (Glycine Soya)—endlessdiversity in their fields. From the biodiversity perspective, biodiversity basedproductivity is higher than monoculture productivity. I call this blindness to thehigh productivity of diversity a “Monoculture of the Mind”, which createsmonocultures in our fields and in our world.The Mayan peasants in the Chiapas are characterised as unproductive becausethey produce only 2 tons of corn per acre. However, the overall food output is20 tons per acre when the diversity of their beans and squashes, theirvegetables their fruit trees are taken into account.In Java, small farmers cultivate 607 species in their home gardens. In sub-Saharan Africa, women cultivate 120 different plants. A single home garden inThailand has 230 species, and African home gardens have more than 60species of trees.Rural families in the Congo eat leaves from more than 50 species of their farmtrees.A study in eastern Nigeria found that home gardens occupying only 2 per centof a household's farmland accounted for half of the farm's total output. In491

Indonesia 20 per cent of household income and 40 per cent of domestic foodsupplies come from the home gardens managed by women.Research done by FAO has shown that small biodiverse farms can producethousands of times more food than large, industrial monocultures.And diversity in addition to giving more food is the best strategy for preventingdrought and desertification.What the world needs to feed a growing population sustainably is biodiversityintensification, not the chemical intensification or the intensification of geneticengineering. While women and small peasants feed the world throughbiodiversity we are repeatedly told that without genetic engineering andglobalisation of agriculture the world will starve. In spite of all empiricalevidence showing that genetic engineering does not produce more food and infact often leads to a yield decline, it is constantly promoted as the onlyalternative available for feeding the hungry.That is why I ask, who feeds the world?This deliberate blindness to diversity, the blindness to nature's production,production by women, production by Third World farmers allows destructionand appropriation to be projected as creation.Take the case of the much flouted “golden rice” or genetically engineeredVitamin A rice as a cure for blindness. It is assumed that without geneticengineering we cannot remove Vitamin A deficiency. However, nature gives usabundant and diverse sources of vitamin A. If rice was not polished, rice itselfwould provide Vitamin A. If herbicides were not sprayed on our wheat fields,we would have bathua, amaranth, mustard leaves as delicious and nutritiousgreens that provide Vitamin A.Women in Bengal use more than 150 plants as greens—Hinche sak (Enhydrafluctuans), Palang sak (Spinacea oleracea), Tak palang (Rumex vesicarious),Lal Sak (Amaranthus gangeticus)—to name but a few.But the myth of creation presents biotechnologists as the creators of VitaminA, negating nature's diverse gifts and women's knowledge of how to use thisdiversity to feed their children and families.The most efficient means of rendering the destruction of nature, localeconomies and small autonomous producers is by rendering their productioninvisible.Women who produce for their families and communities are treated as `nonproductive’and èconomically’ inactive. The devaluation of women's work, andof work done in sustainable economies, is the natural outcome of a systemconstructed by capitalist patriarchy. This is how globalisation destroys localeconomies and destruction itself is counted as growth.492

And women themselves are devalued. Because many women in the rural andindigenous communities work co-operatively with nature's processes, theirwork is often contradictory to the dominant market driven `development’ andtrade policies. And because work that satisfies needs and ensures sustenanceis devalued in general, there is less nurturing of life and life support systems.The devaluation and invisibility of sustainable, regenerative production is mostglaring in the area of food. While patriarchal division of labour has assignedwomen the role of feeding their families and communities, patriarchaleconomics and patriarchal views of science and technology magically makewomen's work in providing food disappear. “Feeding the World” becomesdisassociated from the women who actually do it and is projected asdependent on global agribusiness and biotechnology corporations.However, industrialisation and genetic engineering of food and globalisation oftrade in agriculture are recipes for creating hunger, not for feeding the poor.Everywhere, food production is becoming a negative economy, with farmersspending more to buy costly inputs for industrial production than the price theyreceive for their produce. The consequence is rising debts and epidemics ofsuicides in both poor and rich countries.Economic globalisation is leading to a concentration of the seed industry,increased use of pesticides, and, finally, increased debt. Capital-intensive,corporate controlled agriculture is being spread into regions where peasantsare poor but, until now, have been self-sufficient in food. In the regions whereindustrial agriculture has been introduced through globalisation, higher costsare making it virtually impossible for small farmers to survive.The globalisation of non-sustainable industrial agriculture is literallyevaporating the incomes of Third World farmers through a combination ofdevaluation of currencies, increase in costs of production and a collapse incommodity prices.Farmers everywhere are being paid a fraction of what they received for thesame commodity a decade ago. The Canadian National Farmers Union put itlike this in a report to the senate this year:“While the farmers growing cereal grains—wheat, oats, corn—earn negativereturns and are pushed close to bankruptcy, the companies that makebreakfast cereals reap huge profits. In 1998, cereal companies Kellogg's,Quaker Oats, and General Mills enjoyed return on equity rates of 56%, 165%and 222% respectively. While a bushel of corn sold for less than $4, a bushelof corn flakes sold for $133 … Maybe farmers are making too little becauseothers are taking too much.”And a World Bank report has admitted that “behind the polarisation ofdomestic consumer prices and world prices is the presence of large tradingcompanies in international commodity markets.”493

While farmers earn less, consumers pay more. In India, food prices havedoubled between 1999 and 2000. The consumption of food grains in ruralareas has dropped by 12%. Increased economic growth through globalcommerce is based on pseudo surpluses. More food is being traded while thepoor are consuming less. When growth increases poverty, when realproduction becomes a negative economy, and speculators are defined as“wealth creators”, something has gone wrong with the concepts and categoriesof wealth and wealth creation. Pushing the real production by nature andpeople into a negative economy implies that production of real goods andservices is declining, creating deeper poverty for the millions who are not partof the dot.com route to instant wealth creation.Women—as I have said—are the primary food producers and food processorsin the world. However, their work in production and processing is nowbecoming invisible.Recently, the McKinsey corporation said: “American food giants recognise thatIndian agro-business has lots of room to grow, especially in food processing.India processes a minuscule 1 per cent of the food it grows compared with 70per cent for the U.S…”.It is not that we Indians eat our food raw. Global consultants fail to see the 99per cent food processing done by women at household level, or by the smallcottage industry because it is not controlled by global agribusiness. 99% ofIndia's agroprocessing has been intentionally kept at the small level. Now ,under the pressure of globalisation, things are changing. Pseudo hygiene lawsare being uses to shut down local economies and small scale processing.In August 1998, small scale local processing of edible oil was banned in Indiathrough a “packaging order” which made sale of open oil illegal and requiredall oil to be packaged in plastic or aluminium. This shut down tiny “ghanis” orcold pressed mills. It destroyed the market for our diverse oilseeds—mustard,linseed, sesame, groundnut, coconut.And the take-over of the edible oil industry has affected 10 million livelihoods.The take over of flour or “atta” by packaged branded flour will cost 100 millionlivelihoods. And these millions are being pushed into new poverty.The forced use of packaging will increase the environmental burden of millionsof tonnes of waste.The globalisation of the food system is destroying the diversity of local foodcultures and local food economies. A global monoculture is being forced onpeople by defining everything that is fresh, local and handmade as a healthhazard. Human hands are being defined as the worst contaminants, and workfor human hands is being outlawed, to be replaced by machines and chemicalsbought from global corporations. These are not recipes for feeding the world,but stealing livelihoods from the poor to create markets for the powerful.494

People are being perceived as parasites, to be exterminated for the “health” ofthe global economy.In the process new health and ecological hazards are being forced on ThirdWorld people through dumping of genetically engineered foods and otherhazardous products.Recently, because of a W.T.O. ruling, India has been forced to removerestrictions on all imports.Among the unrestricted imports are carcasses and animal waste parts thatcreate a threat to our culture and introduce public health hazards such as theMad Cow Disease.The US Centre for Disease Prevention in Atlanta has calculated that nearly 81million cases of food borne illnesses occur in the US every year. Deaths fromfood poisoning have gone up more up more than four times due toderegulation. Most of these infections are caused by factory farmed meat. TheUS slaughters 93 million pigs, thirty seven million cattle, two million calves, sixmillion horses, goats and sheep and eight billion chickens and turkeys eachyear.Now the giant meat industry of US wants to dump contaminated meatproduced through violent and cruel methods on Indian consumers.The waste of the rich is being dumped on the poor. The wealth of the poor isbeing violently appropriated through new and clever means like patents onbiodiversity and indigenous knowledge.Patents and intellectual property rights are supposed to be granted for novelinventions. But patents are being claimed for rice varieties such as the basmatifor which my Valley—where I was born—is famous, or pesticides derived fromthe Neem which our mothers and grandmothers have been using.Rice Tec, a U.S. based company has been granted Patent no. 5,663,484 forbasmati rice lines and grains.Basmati, neem, pepper, bitter gourd, turmeric…….every aspect of theinnovation embodied in our indigenous food and medicinal systems is nowbeing pirated and patented. The knowledge of the poor is being converted intothe property of global corporations, creating a situation where the poor willhave to pay for the seeds and medicines they have evolved and have used tomeet their own needs for nutrition and health care.Such false claims to creation are now the global norm, with the Trade RelatedIntellectual Property Rights Agreement of World Trade Organisation forcingcountries to introduce regimes that allow patenting of life forms andindigenous knowledge.495

Instead of recognising that commercial interests build on nature and on thecontribution of other cultures, global law has enshrined the patriarchal myth ofcreation to create new property rights to life forms just as colonialism used themyth of discovery as the basis of the take over of the land of others ascolonies.Humans do not create life when they manipulate it. Rice Tec's claim that it hasmade “an instant invention of a novel rice line”, or Roslin Institute's claim thatIan Wilmut “created” Dolly denies the creativity of nature, the selforganisationalcapacity of life forms, and the prior innovations of Third Worldcommunities.Patents and intellectual property rights are supposed to prevent piracy. Insteadthey are becoming the instruments of pirating the common traditionalknowledge from the poor of the Third World and making it the exclusive“property” of western scientists and corporations.When patents are granted for seeds and plants, as in the case of basmati, theftis defined as creation, and saving and sharing seed is defined as theft ofintellectual property. Corporations which have broad patents on crops such ascotton, soya bean, mustard are suing farmers for seed saving and hiringdetective agencies to find out if farmers have saved seed or shared it withneighbours.The recent announcement that Monsanto is giving away the rice genome forfree is misleading, because Monsanto has never made a commitment that itwill never patent rice varieties or any other crop varieties.Sharing and exchange, the basis of our humanity and of our ecological survivalhas been redefined as a crime. This makes us all poor.Nature has given us abundance, women's indigenous knowledge ofbiodiversity, agriculture and nutrition has built on that abundance to createmore from less, to create growth through sharing.The poor are pushed into deeper poverty by making them pay for what wastheirs. Even the rich are poorer because their profits are based on the theftand on the use of coercion and violence. This is not wealth creation butplunder.Sustainability requires the protection of all species and all people and therecognition that diverse species and diverse people play an essential role inmaintaining ecological processes. Pollinators are critical to fertilisation andgeneration of plants. Biodiversity in fields provides vegetables, fodder,medicine and protection to the soil from water and wind erosion.As humans travel further down the road to non-sustainability, they becomeintolerant of other species and blind to their vital role in our survival.496

In 1992, when Indian farmers destroyed Cargill's seed plant in Bellary,Karnataka, to protest against seed failure, the Cargill Chief Executive stated,“We bring Indian farmers smart technologies which prevent bees fromusurping the pollen”. When I was participating in the United Nations BiosafetyNegotiations, Monsanto circulated literature to defend its herbicide resistantRoundup ready crops on grounds that they prevent “weeds from stealing thesunshine”. But what Monsanto calls weeds are the green fields that provideVitamin A rice and prevent blindness in children and anaemia in women.A worldview that defines pollination as “theft by bees” and claims biodiversity“steals” sunshine is a worldview which itself aims at stealing nature's harvestby replacing open, pollinated varieties with hybrids and sterile seeds, anddestroying biodiverse flora with herbicides such as Roundup. The threat posedto the Monarch butterfly by genetically engineered bt crops is just one exampleof the ecological poverty created by the new biotechnologies. As butterflies andbees disappear, production is undermined. As biodiversity disappears, with itgo sources of nutrition and food.When giant corporations view small peasants and bees as thieves, and throughtrade rules and new technologies seek the right to exterminate them,humanity has reached a dangerous threshold. The imperative to stamp out thesmallest insect, the smallest plant, the smallest peasant comes from a deepfear—the fear of everything that is alive and free. And this deep insecurity andfear is unleashing the violence against all people and all species.The global free trade economy has become a threat to sustainability and thevery survival of the poor and other species is at stake not just as a side effector as an exception but in a systemic way through a restructuring of ourworldview at the most fundamental level. Sustainability, sharing and survival isbeing economically outlawed in the name of market competitiveness andmarket efficiency.I want to argue here tonight that we need to urgently bring the planet andpeople back into the picture.The world can be fed only by feeding all beings that make the world.In giving food to other beings and species we maintain conditions for our ownfood security. In feeding earthworms we feed ourselves. In feeding cows, wefeed the soil, and in providing food for the soil, we provide food for humans.This worldview of abundance is based on sharing and on a deep awareness ofhumans as members of the earth family. This awareness that in impoverishingother beings, we impoverish ourselves and in nourishing other beings, wenourish ourselves is the real basis of sustainability.The sustainability challenge for the new millennium is whether global economicman can move out of the worldview based on fear and scarcity, monoculturesand monopolies, appropriation and dispossession and shift to a view based on497

abundance and sharing, diversity and decentralisation, and respect and dignityfor all beings.Sustainability demands that we move out of the economic trap that is leavingno space for other species and other people. Economic Globalisation hasbecome a war against nature and the poor. But the rules of globalisation arenot god—given. They can be changed. They must be changed. We must bringthis war to an end.Since Seattle, a frequently used phrase has been the need for a rule basedsystem. Globalisation is the rule of commerce and it has elevated Wall Streetto be the only source of value. As a result things that should have high worth—nature, culture, the future are being devalued and destroyed. The rules ofglobalisation are undermining the rules of justice and sustainability, ofcompassion and sharing. We have to move from market totalitarianism to anearth democracy.We can survive as a species only if we live by the rules of the biosphere. Thebiosphere has enough for everyone's needs if the global economy respects thelimits set by sustainability and justice.As Gandhi had reminded us: “The earth has enough for everyone's needs, butnot for some people's greed”.498

ALLEGATED 8:Phyto-Therapy (Plant therapy) is a classical medical therapy, NOT analternative therapy.Phyto-therapy means plant therapy (from the Greek Fitos, plant).It has always been used by those who wanted to keep the sick alive and if possible, cure them.In Ancient times it was priests who used this ‘technique’, but from Hippocrates onwards theherbalists-doctors practiced ‘Medicine’, in the modern sense of the term, that is, the art of knowinghow to administer the precise plant extracts, chosen and proportioned according to the illnessesdiagnosed.The oldest evidence of plant therapy comes from the Egyptians, around about 4000 BC, but we alsohave evidence from the Chinese, Tibetans and Indians: for example a Chinese text from 3000 BC(Pen Tsao), contains over a thousand natural remedies, and even then there were many remediesagainst cancer. Even in the West we had various remedies proposed against cancer: among these,alongside various herbs advised, it is important to remember the words of Hippocrates of Kos, whosaid that if a tumor was surgically removed, it had less chance of healing, while if the patientfollowed an exclusively herbal diet, without removing the tumor, he would have a better chance ofrecovery …….To treat patients using herbs was therefore the duty of every doctor, because the knowledge learnedby Pliny the Elder, and before him, the Greeks and the ancient schools of Alexandria and the Eastwas based on the logical deduction of a physical-pathological process in action, which needed atreatment based on the official medical knowledge of the time: thousands of plants cataloguedaccording to the illnesses they could cure, and the diagnosis, therapy and prognosis were entrustedto the experience of the individual doctor…..Thus, up to the XIX century, western medicine was only practiced using tisanes and infusions ofherbs, on the basis of thousands of years of experience which from Hippocrates onwards had beencalled ‘Medicine’, that is the art of knowing how to treat and heal, an art which was even governedby the ethical code of each individual doctor, and of which today we remember only the so-called‘Hippocratic Oath’, forgetting the precious teachings about food, hygiene, and the correct herbalpotions, all essential for maintaining or restoring perfect health…….Thus, in ancient medical knowledge, above all of the Greeks, Etruscans and Romans, we can seehow they carried out treatments without apparent use of antibiotics, and even complex surgicaloperations….The ancients really knew many herbs and plants very well, and there are famous and importantdocuments which show their profound medical and surgical knowledge, both in times of peace andtimes of war, showing how they managed without antibiotics and vaccinations; and so it is useful tolook at important medical documents such as the “Erbario Greco”, by Dioscorides, or “StoriaNaturale” by Pliny the Elder, together with important texts from the Age of Enlightenment, forexample the still relevant “Erbario Novo” by Durante Castore, published in Venice in 1617: allbooks still valid as points of reference and to give an idea of the medicinal values of many plants,which are unfortunately very little known today and in some cases even forgotten.Without forgetting organic chemistry, which was able to reproduce such sterile molecules in orderto use them for intra-muscular, intravenous, intra-vault or intra-arterial injections, we mustreconsider the usefulness of medicines if they are for not for intra-parenchymal use, taking intoconsideration that it is much more efficacious and curative to use plants in any situation which isnot necessarily ‘sterile’, if it is compatible with our notions of modern medicine.499

There are about 800,000 plant species in nature. About 90% of these are estimated to containvitamins or pro-vitamin substances essential for the normal functioning of human bio-chemistry.Today Biochemistry (see for example Albert L. Lehninger ‘The Principles of Biochemistry’) is stillstudied in depth because the evolution of mammals, which has lasted more than 60 million years,happened fundamentally through the external use of essential vitamin and pro-vitamin substancesderived basically from plants, in a complex synergic action which even today is not clearlyunderstood in its endocellular dynamics and above all in its DNA.It can therefore be claimed that the majority of current illnesses could substantially derive from asimple lack of vitamins: a lack which could more or less be either due to environmental factors andthe individual’s genetic predisposition.It is thought that the number of vitamins and pro-vitamin compounds amount to at least 13.000 –15.000 different substances, many of which are not even known today.Therefore, if, as the author proposes, it is true that diseases are caused by an enzymatic lack ofvitamins (shown by a highly sophisticated biochemical component such as mammals, which haveevolved over millions of years on a mainly vegetarian diet) then the majority of diseases orsyndromes could be treated and cured by a correct choice of particular plants (Natural Remedies),not only from Europe but also from Asia, Africa, Oceania and the Americas.The scientific study of individual officinal plants must therefore be subject to a worldwide debate,with the aim of finding more efficient medical treatments, giving value to the ancient knowledge ofplant medicines, and by using modern instruments of analysis which confirm the tens or hundredsof active ingredients contained in each individual plant.This ‘Natural Remedy’ is presently being studied on a personal level (confidential data), but thereader is invited to consult up-to-date scientific works (SEE for example the magazine ‘Fitoterapia’in English, available on the INTERNET. http://www.indena.it/fitoterapia_index.asp).Bibliography:Old:“Il regime” di Ippocrate di Cos“Aforismi” di Ippocrate di Cos"Erbario greco" di Dioscoride“Materia medica” di Dioscoride (vers. Ruellio – VE 1532)"Storia Naturale" di Plinio il Vecchio“De Medicina” di Celso“Opere scelte” di Galeno (UTET 1976)“De simplicium medicamentorum facultatibus” di Galeno“De compositone medicamentorum sec. Locus” di Galeno“Collectorio” di Mesuè“ Kitab Al’Murchid” di Razes“Qanun fi’t tibb” di Avicenna“Discorsi sui 6 libri della materia medicinale di Pedacio Dioscoride Anarzabeo” (Mattioli, Venezia 1557)"Herbario Novo" di Durante Castore (Venezia 1617)Modern:Kapoor L.D.: CRC Handbook of Ayurvedic Medicinal Plants, CRC Press, Inc. Boca Raton, FloridaLeslie Taylor: “Herbal Secrets of the Rainforest. The healing power of over 50 medicinal plants you should know about.Prima Health”. A division of Prima Publishing.Joseph E. Pizzorno jr and Michael T. Murray: Textbook of Natural Medicine, Churchill Livingstone, London, HarcourtBrace and Company, 1999Dewick PM.: “Tumor Inhibitors from Plants”, Treasend Evans, Pharmacognosy (13 th .Ed.), 1989, Volumenes 1-3.Tina Cecchini : Enciclopedia delle Erbe e delle Piante medicinali. Giovanni De Vecchi Editore Milano.Inverni della Beffa : Manuale di Fitoterapia500

G. Penso: Piante medicinali nella terapia medica. Ediz. OEMFR. Della Loggia: Piante medicinali per infusi e tisane. Ediz. OEMFPeter e Ingrid Schnfelder : Atlante delle piante medicinali (Franco Muzio Ed.)J. Valnet : Fitoterapia. Cura delle malattie con Piante. Aldo Martello. Giunti editore, 1976J.Valnet : Cura delle malattie con le essenze delle piante, Aldo Martello. Giunti editore, 1976J. Valnet : Cura delle malattie con ortaggi, frutta e cereali, Aldo Martello. Giunti editore, 1976L. Pomini : Erboristeria italiana. Edizioni Minerva Medica, 1973L.P. Da Legnano: Le piante medicinali nella cura delle malattie umane. II Edizione. Edizioni mediteranee, 196, RomaF. Bianchini: F. Corbetta: I frutti della terra. Arnoldo Mondadori editore, 1973, Milano.F. Bianchini: F. Corbetta: Le piante della salute. Arnoldo Mondadori editore, 1975, Milano.Giovanni Negri : Erbario figurato, Ulrico Hoepli editore, ristampa, 1979, MilanoBecker H., Reichling S. - Disch, Apoth. 1981M. Pedretti: Guida agli integratori alimentari , Musumeci editore, 1986Paolo Rovesti : Piante officinali italiane libro 1, Unione tecnica italiana farmacisti U.T.I. FARPaolo Rovesti : Piante officinali italiane libro 2, Unione tecnica italiana farmacisti U.T.I. FARUmberto Boni: Scoprire, riconoscere, usare le erbe, Fratelli Fabbri Editori, 1977, MilanoCleto Gambioli: Curarsi con erbe e piante, Aldo Garzanti editore, 1977Emilio Sanna : Erbe amiche, Armando Curcio editorePrimo Boni: Nutrirsi al naturale con le erbe selvatiche. Edizioni PaolineGianpaolo Porlezza Taroni: il giardino degli aromi. Rizzoli editore, 1977, MilanoArturo Cerutti : Piante medicinali e alimentari, Loescher editore, TorinoLuigi Palma : Fitoterapia moderna. Società Editrice Internazionale, 1958, TorinoRenzo Corcos: Tornare alla Natura, Sugar Editore & C., MilanoPaul Schauenberg e Ferdinand Paris: Le piante medicinali, Newton Compton Editori srl, 1977, RomaAdriano Fiori: nuova flora analitica d'Italia. Edizioni agricole, Bologna, 1969Vincent d'Auffray : Guide pratique des plantes medicinales. Production de Paris - N.O.E., 1973Obertel Bauer: La santé par les plantes. Editions Alsacia.Jean de Sillé: Des plantes pour vous guerir. Editions DanglesFabrice Bardeau : Curarsi con i fiori. Arnoldo Mondadori Editore, 1977, MilanoLelord Kordel: Rimedi popolari naturali. Rizzoli editore, 1976, MilanoAlberto Fidi: Erbe e piante medicinali. Casa Editrice Armando Gorlini, MilanoE. Adami : Farmacologia e Fearmacoterapia, Ist. Edit. CisalpinoLemli J., Cuveele J.: Phytochemistry, 1975PH. Francaise IX ed. deuxiemme partie: Fiches de documentation de pratique officinale, 1980G. Murari : Botanica farmaceutica, Ed. Esculapio, 1980G. Murari Colalongo: Formulario di Fitoterapia, Ed. SepemJ. Bruneton : Elements de Phytochimie et de pharmagnosie, 1987P. Belaiche: Fitoterapia familiare, 1988A. Poletti: Fiori e piante medicinali, 1985, Musumeci edit. Vol. 1, 2, 3Benigni, Capra, Cattorini : Piante medicinali: chimica, farm. e ter. (I e II volume)501

ALLEGATED 9: Open Letter to the Governmentfrom : http://www.psrast.org/psrlet.htmWe, the undersigned scientists and physicians, demand that all genetically engineered (GE) foodsbe withdrawn from the market unless they have undergone rigorous safety assessment includinglong term testing on animals and humans. This includes all GE foods that have been approved onthe basis of the principle of "substantial equivalence". In practice, all GE foods on the market havebeen insufficiently tested and should thus be withdrawn.The reasons are as follows:The principle of "Substantial equivalence" is based on the assumption that if a GE food and itsnatural counterpart are compared for a limited number of chosen traits, and are found to be similar,then there is no reason to submit the GE food to careful testing.This assumption has no basis in science. It does not take into account the possibility that in eachseparate case, insertion of genes into DNA may cause metabolic disturbances, or unpredictablygenerate potentially harmful substances. This has been predicted on molecular biological grounds[1] [2] [3] and also demonstrated in experimental cases [4]. Especially slowly acting harmfulsubstances may be very difficult to detect. Thus there is a considerable risk they will be overlookedif the superficial tests used for "establishing substantial equivalence" are applied.The insufficiency of the principle of substantial equivalence is briefly summarized in a webdocument [5] and is explained in more detail in a recent article in the science journal "Nature" [6].Only by applying rigorous food safety testing, including long term testing on animals (preferablylifetime) and humans (at least 3-5 years), is it possible to minimize the risk of missing unpredictedharmful substances [7].ConclusionThe principle of substantial equivalence has no scientific basis. Since this is the standard which hasbeen used for approving GE foods, it follows that none of the GE foods on the market today can beconsidered safe. In the worst case exposure of the population may have disastrous consequences.Therefore, GE foods at present on sale should be withdrawn from the market immediately. No newGE foods should be introduced until proper methods of assessment have been applied.References:1. Antionou M, Cummins J, Daniel EE, Epstein S , Howard C V, Orskov B, Pusztai A, Raghuram N, Seralini G-E,Wuerthele S. "The safety of GE foods. Reasons to expect hazards and the risk for their appearance" athttp://www.psrast.org/defknfood.htm2. Fagan J, "Assessing the safety and nutritional quality of genetically engineered foods" athttp://www.psrast.org/jfassess.htm3. National Research Council (USA), . "Genetically Modified Pest Protected Plants". p. 137 (Washington, D.C.:National Academy Press, 2000). ISBN 0309069300. On-line copy at: http://www.nap.edu/html/gmpp/4. a) Violand BN et al. Protein Science. 3:1089-97, 1994. b) Reddy SA, Thomas TL.Nature Biotechnology, vol 14, sid639-642, May 1996. c) Inose, T. Murata, K. Int. J. Food Science Tech 30: 141-146, 1995. d) Nordlee, J.A. et al. TheNew England Journal of Medicine 14: 688-728; 1996.5. PSRAST, "Inadequate safety assessment of GE foods" at http://www.psrast.org/subeqow.htm6. Millstone E, Brunner E and Mayer S, "Beyond Substantial Equivalence", Nature 401: 525-526, 7 Oct 1999.7. Fagan J, "Testing the safety of genetically engineered foods" at http://www.psrast.org/jfreqtst.htm502

ALLEGATED 10 : November 2005: The last letter from AmericaWe received this letter via e-mail before our WEB site www.lecurenaturali.com andits very important section in English (www.lecurenaturali.com/natural_cures ) wereclosed. In particular, our site gave space to the American pacific opposition to GMOsand Chemotherapy since 2003.Here we report the letter, in order to let people know the truth….Dear Dr Nacci,Thank you for the very fine piece on GMO. It is the best I have seen because it is simple and can be understood by all.We certainly stand with you and call for an elimination of all GMO activities.I send you information which we send to patients who are interested in Alternative Cancer Therapies for cancer.Sincerely,Frank D WiewelFormer Chairman,Pharmacological and BiologicalTreatments CommitteeOffice of Alternative Medicine (OAM)National Institutes of Health (NIH)Founder,People Against CancerPeople Against Cancer - Who we are - What we doThank you for your inquiry about the work of People Against Cancer.This year 1,500,000 Americans will be diagnosed with cancer and 750,000 will die despite the best standard therapy.People Against Cancer is a non-profit membership organization dedicated to new directions in the "war on cancer."Standard TherapyThe standard therapy for cancer includes surgery, radiation, chemotherapy and hormonal therapy. These are, at best,short term fixes.Address the ProblemNone of these options addresses the problem. Only the symptom. The symptom is the tumor. The true problem is thefailure of the immune system to patrol, identify, isolate and eliminate the cancer cells as they routinely arise in the body.Innovative and Wholistic TherapyWe prefer innovative and wholistic concepts which include comprehensive detoxification by eliminating toxins fromthe food, air, water, environment - and the body. We believe it is essential to address the fundamental issues of diet,nutritional supplements all the way through the state-of-the-art innovative biological therapies.For People With Cancer, we have developed a program called The Alternative Therapy Program to help identify thefinest comprehensive treatment options throughout the world.We will be happy to help you find the best specific individualized cancer therapy for you, your friend or your loved onethrough our Alternative Therapy Program.The Alternative Therapy Program Simple Steps:503

1) Join People Against Cancer as a Sustaining Member. You can join on the Website at:http://www.peopleagainstcancer.net/detail.asp?product_id=0752) Complete our Medical History Questionnaire. Collect and send us all of your medical records. You can downloadMembership information, our Questionnaire and our Medical Records Release form to get your records at:http://www.peopleagainstcancer.net/cancer_inforequest.asp3) We submit your records to the International Physicians Network - the finest innovative and conventionalphysicians from around the world;4) We collect their extensive consultations, opinions and recommendations;5) We send you an extensive written report and you set up a personal telephone consultation and have access toongoing consultations throughout the year.To Access The Alternative Therapy Program By MailIf you filled in our form and requested a written copy of our information, and you included your name, address, phone,fax and email, we will send you additional information by Priority Mail about who we are and what we do.To Access The Alternative Therapy Program By FaxYou can fax us at 515-972-4415 (On 24 hours). If you include your fax number, we will fax you information about allof our programs, including The Alternative Therapy Program and details of how to access our programs or getfurther information.To Access The Alternative Therapy Program On The Web1) Go to: http://www.peopleagainstcancer.net/cancer_inforequest.asp1) Read: The details of the Alternative Therapy Program at:http://www.peopleagainstcancer.net/cancer_alternative.asp3) Go to: http://www.peopleagainstcancer.net/cancer_inforequest.aspDownload The Medical History Questionnaire after filling out our simple form at:4) Print: The Medical History Questionnaire (Link in Blue) (SEE Note below)5) Complete: the Medical History Questionnaire and use the Medical Records Release Form to get all of your medicalrecords6) Join: People Against Cancer for best treatment options and consultation in the world.To Access The Alternative Therapy Program By PhoneIf you have any questions feel free to call us at 515-972-4444, between the hours of 10-5 Central Daylight Time (CDT)Monday -Friday.People Against Cancer604 East StPO Box 10Otho, IA 50569-0010Phone: 515-972-4444Fax: 515-972-4415email: Info@PeopleAgainstCancer.comweb: www.PeopleAgainstCancer.comForeign Friends: Sadly, we can not send "Free Information" by mail to our friends outside of the US, because ofthe tremendous number of requests and costs. Please click on the URL below to download "Free Information"from People Against Cancer information form on the web athttp://www.peopleagainstcancer.net/cancer_inforequest.asp504

The importance of a Healthy and Self-sufficient AgricultureAgriculture is the most important activity as it allows to satisfy the primary need ofman, i.e. eating. A country self-sufficient in the agricultural sector is not subjected toblackmails of the supplying countries. A self-sufficient country with regard to foodcan print banknotes and increase the currency thus raising salaries and pensionswithout causing inflation – because the products are abundant and are obtained to besold. This can take place thanks to a monetary policy; Italy renounced this policy anddelegated it first to the Bank of Italy – a private bank – and then to Europe.There are two kinds of monetary problems:1) abundance of products and lack of money; in this case the Government muststamp banknotes thus increasing the currency, salaries and pensions, in order tosupport the national production system which needs money to go ahead.2) lack of goods and abundance of money; this situation causes inflation and thenthe Government must increase taxes to decrease the currency.If in a country, agriculture is not enough productive, the State will not raise salaries inorder to avoid an increase in prices of food, whose consumption is dailyindispensable. A shortage of foodstuffs is the main cause of inflation.The following objection could be raised: “I could buy low-priced foodstuffs abroadtaking advantage of national industry profits and so I have no problems”.The problem is that world agricultural production is insufficient and there is a risk ofpolitical-economic dependence on supplier countries.Furthermore, in order to maintain or establish its control, the supplier countrysabotages client’s agricultural production through a secret chemical and biological warand laws against agriculture, which were promulgated by blackmailed – and bribed –political executives of the client country.All is possible in a world where – instead of Christian brotherhood – the crudestcynicism and the attempt of some people to rule ideologically and economically otherpeople are spreading.505

ALLEGATED 12: Jason Vale : an American HeroJason Vale risks prison for apricot seedsFROM:http://www.newmediaexplorer.org/sepp/2003/07/12/fda_vs_jason_and_vitamin_b17.htmJason Vale, a cancer survivor, former arm wrestling world champion and self-describedentrepreneur, who is on trial for allegedly violating a government order that he stop promoting theuse of apricot seeds as a cure for cancer faces a possible prison sentence, according to an article beNathan C. Masters, correspondent of CNSNews.The trial, which lasted from Monday 14 July through Thursday, is now adjourned and the jury isexpected to deliver its verdict in a matter of days.Update 22 July 2003Jason Vale held without bail, pending sentencing, after a jury found him guilty of ... sellingapricot seeds.FDA Commissioner McCLELLAN stated that "The FDA takes seriously its responsibility to protectpatients from unproven products being peddled on the internet by modern day snake oil salesmensuch as the defendant in this case. There is no scientific evidence that Laetrile offers anything butfalse hope to cancer patients."Cancer Survivor Faces Possible Prison for Selling Apricot SeedsBy Nathan C. MastersCNSNews.com CorrespondentJuly 18, 2003(CNSNews.com) - Federal jurors in Brooklyn, N.Y., must decide the fate of Jason Vale, a cancersurvivor, former arm wrestling world champion and self-described entrepreneur, who is on trial forallegedly violating a government order that he stop promoting the use of apricot seeds as a cure forcancer.Closing arguments in the case were held Thursday with Vale serving as his own attorney andaccusing the government of setting him up. But Vale's alleged defiance of the Food and DrugAdministration's (FDA) consent decree, issued in 2000, could land him with a 20-year prisonsentence. The FDA claims the Apricot pits, more than 100,000 of which federal agents reportedlyseized in a raid on Vale's basement, have no therapeutic value.Vale was diagnosed with terminal cancer in 1986 and suffered from the disease for eight years,enduring chemotherapy, radiation treatments and an operation to remove a tumor. But in 1994, Valesaw a video touting apricot seeds as a cure for cancer and began taking the seeds, which releaseorganic cyanide into the system. Vale claims his use of the seeds along with his faith in Godeliminated the tumor and saved his life.506

"I have watched first-hand as apricot seed consumption has helped to shrink tumors in almost everycancer patient [with whom] I've dealt," said Vale. "I have also followed horror stories from manyof those using highly toxic chemo and radiation therapies."Vale's legal troubles began when he started selling a concentrated form of the vitamin found inapricot seeds, known as laetrile or amygdalin, to other cancer patients over the Internet.The FDA is currently refusing comment on this matter, but according to a warning letter sent toVale in 1998, the agency stated that it considered laetrile to be a "new drug," and as such, was notapproved for sale or importation. The FDA obtained an injunction in November 2000, forbiddingVale and his company, Christian Brothers Contracting Corporation, from selling or promoting theuse of laetrile as a cancer treatment.Following undercover investigations by the FDA, the agency alleged that Vale had continued to selland promote laetrile in violation of the consent decree and recommended in March 2002 that Valebe prosecuted for criminal contempt.Eliezer Ben-Joseph, a doctor of naturopathy and host of the Natural Solutions talk radio show in ElPaso, Texas, describes the government's efforts as "ludicrous.""It's a vindictive prosecution," said Ben-Joseph. "We're talking about apricots , and yet thegovernment is so drastically opposed to having this information out."The U.S. government maintains that because Vale made therapeutic claims about his laetrileproducts, the apricot seeds should be treated as drugs and therefore require FDA approval beforethey could be sold or distributed within the United States. Furthermore, the government maintainsthat laetrile has no medicinal benefits. A National Cancer Institute report obtained byCNSNews.com concluded that, "laetrile has shown little anti-cancer activity in animal studies andno anti-cancer activity in human clinical trials."Ben-Joseph doubted the credibility of those clinical trials, and noted that, "several concerns havebeen expressed about the way the study was conducted." He pointed out that some recentlydeveloped cancer treatments use artificial cyanide, which is very similar to the organic cyanide thatlaetrile emits."It's not a cure; there is no cure for cancer, but there are things that we can do that augment howmetabolism works," he noted. "These are chemicals that the body would use to detoxify or get rid ofcancer."Regardless of their efficacy, Ben-Joseph argues, apricot seeds are no more dangerous than othernatural remedies, and he believes they should be legal for use as a cancer treatment.Vale is not alone in touting laetrile as a cure; Donald Factor, the son of cosmetic tycoon MaxFactor, sought natural cancer treatment in Mexico 17 years ago. After being treated with laetrile andother natural remedies, Factor's cancer disappeared, and he is still alive today.And Vale claims that his apricot seed products have helped over 30,000 cancer patients, many ofwhose personal testaments are documented on Vale's website .Ben-Joseph considers Vale's case a "freedom issue" and calls the government's prosecution aninappropriate use of the judicial system.507

"To make a law that says that the public cannot eat an apricot pit, because they think it might keeppeople from going to regular cancer therapy, I think is a ludicrous jump in jurisdiction," he said.Vale also faced legal troubles in 1998 when America Online sued him for allegedly sending over 20million "spam" e-mail messages to its subscribers. A federal judge awarded AOL $631,585 indamages. Vale and his attorneys could not be reached for comment regarding the AOL case.****************************FDA vs. Jason - and vitamin B17CategoriesHealthNew York - on Monday 14 July, the FDA instigated action against former arm-wrestling championJason Vale for selling apricot seeds and telling his story of how he got cured of cancer will have itsday in court. (SEE Call for help - FDA vs Jason on 14 July)Jason was apparently set up by the FDA, whose primary function might seem to be the protection ofpharmaceutical interests from competition by effective, food-based natural alternatives to drugtreatment, rather than the protection of Joe Doe Public from being taken advantage of."They are trying to hold me in contempt of the original injunction because I referred FDA plants aphone number where to get the seeds. It's funny because in the tapes ... the FDA agents arerepeatedly trying to get me to tell them they'll be cured ... and I kept saying that this is not a cure,that they had to pray and juice and do other things .. "Apart from the various legal technicalities and even the obvious constitutional implications,the more basic question this case brings to the fore is whether there should be a legal andcourt-backed monopoly by pharmaceutically controlled medicine on "healing" or whether allsystems of prevention and therapy should be allowed to compete on an equal footing.Unless we put medical freedom into the Constitution, the time will come when medicine willorganize into an undercover dictatorship ... To restrict the art of healing to one class of men anddeny equal privileges to others will constitute the Bastille of medical science. All such laws are un-American and despotic and have no place in a republic ... The Constitution of this republic shouldmake special privilege for medical freedom as well as religious freedom."508

Benjamin Rush, M.D., signer of The Declaration of Independence, physician to GeorgeWashington.from THE AUTOBIOGRAPHY OF BENJAMIN RUSHThe International Council for Health Freedom, in its latest newsletter, takes up the case of JasonVale.FDA unleashes an apricot kernel probe; NY's Jason Vale sticking with Bible and ConstitutionUSA - A 35-year-old New York entrepreneur whose various websites have probably done morethan any other medium to keep interest in the "vitamin B17" theory of cancer prevention andtreatment alive in modern times, goes on trial on July 14 in a tangled legal snarl initiated by theFDA five years ago.Jason Vale, through whose "Christian Brothers Contracting Corp." Internet outlets many thousandsof pounds of apricot kernels were sold throughout the USA - and along with them but in lesseramounts other products construable as laetrile in tablet and liquid form - has been mounting his ownresponse to a federal charge of "criminal contempt" for alleged violations of preliminary andpermanent injunctions issued in 2000 by a New York federal district court.Vale, an exuberant former arm-wrestling champion and ardent Christian who cites the Bible indefense of his espousal of apricot kernels in the prevention and management of cancer, and variousattorneys who have worked with him, believes there are so many Constitutional problems with thehandling of his investigation by the FDA that prospects for ultimate victory in court are still verymuch alive.Vale, who has described in detail how alternative methods - particularly consuming large amountsof "vitamin B17"-laden apricot kernels as well as the Catapano typhoid vaccine approach - literallycured him of a rare "form" of cancer with which he was first diagnosed at age 18, has made various"B17" products available to 35,000 people, he told ICHF, although he is no longer selling them"just to play it safe". He never uses the word "laetrile".To date, after about 35,000 customers, not one has come back and said that they or their familymember came down with cancer even though they were taking the seeds - not one," he told ICHF.The highly articulate New Yorker, whose educational background is psychology (Queens College)and who stated he does not "play doctor" and has never claimed that apricot kernels or theirpresumed active ingredient amygdalin cures cancer, states of the earlier civil order "that Ireluctantly signed":" ... I [agreed] not to sell apricot seeds in violation of FDA statutes, also that I would not promote[them] in violation of FDA statutes. I never agreed to stop telling my story or for that matter tellingpeople what it does. I never agreed to stop selling apricot seeds that were not in violation of FDAstatutes."He reached national prominence when he appeared on the television show "Extra" as the armwrestler apparently self-cured of cancer with apricot kernels, provoking a response so great that theepisode was run a second time.509

Some observers believe that his catapulting into high-profile levels is what particularly stimulatedthe FDA investigation of his websites.In an April 17 letter to New York Rep. Eliot Engel, a Texas believer in Jason Vale wrote: " ... Jasonhas inspired and helped over 100,000 people, many of [whom] were handed the same deathsentence Jason was given over 17 years ago. These people are from all walks of life and have hadvarious types of cancers. Through proper diet, nutrition, and the implementation of apricot seeds intheir daily diets, they have one-by-one created their own success stories that they will now live totell ..."I am praying for your wisdom and advice regarding the basic fundamental rights of an Americancitizen to share such an amazing story and to give those who choose alternative treatments anopportunity to get better when modern medicine abandons them."Vale, who has undergone raids, undercover investigations, the confiscation of computers, files andrecords but as of this writing has never had a "bill of particulars" presented to him to explain exactlywhat it is he is alleged to have done improperly, faced a bond of more than $ 800,000 let aloneundetermined amounts to be spent in an ever more complicated legal battle.They are trying to hold me in contempt of the original injunction because I referred FDA plants aphone number of where to get the seeds. It's funny, because in the tapes that they turned over forevidence, the FDA agents are repeatedly trying to get me to tell them they'll be cured ... and I keptsaying that this is not a cure, but that they had to pray and juice and do other things," he said.In the meantime, Vale's current major website is a repository of first-person anecdotal reports ofimpressive responses in cancer, high blood pressure and other things primarily due to theconsumption - and, in FDA eyes, the frequent over-consumption - of apricot kernels.While Vale learned of the kernels/seeds through reading the book and watching the videotape oflaetrile activist G. Edward Griffin (World without Cancer) over time he came to believe that theseeds are far more potent in preventing and managing cancer than the refined laetrile products, hetold ICHF.The laetrile wars of the 1970s and early 1980s - during which 24 states decriminalized the use oflaetrile in its various forms as an anti-cancer treatment - became the greatest medical controversy inthe USA in the 20th century with the possible exception of chiropractic.The effort to decriminalize laetrile and protect doctor/patient access to what amounted to anunpatentable natural extract of apricot kernels led to the development of a sociopolitical movement- for freedom of choice with informed consent for doctor and patient - and the burgeoning naturalmedicines outbreak of the 1980s/1990s and the current millennium (SEE Culbert, Griffin, Kittler,Halstead).Jason Vale, whose own incurable cancer seemed to have been wiped out and kept at bay ever since,primarily by apricot kernels, joined forces with two friends to set up the ChristianBrothers Websitein the 1990s to make both information and certain products available.His problems began Oct. 28, 1998, when the area FDA office sent him a three-page "warning letter"concerning "your promotion and distribution of the unapproved drug Laetrile in the form of yourproducts 'apricot seeds', 'vitamin B17 tablets' and 'amigdalina' ampoules. Labeling for these510

products make[s] therapeutic claims which cause the products to be drugs as defined in Section 201(g) of the Federal Food, Drug and Act ..."Vale and his attorneys have argued that among problems with the polyfaceted federal probe ofJason Vale and ChristianBrothers are the facts that he was never formally indicted by a Grand Jury,that some of the evidence FDA seized in their investigation has not been returned, that Vale hasnever received a full accounting ("bill of particulars") of his alleged wrongdoings, and that there areimplicit conflicts of interest in the fact that an attorney serving as a criminal prosecutor also servesas a civil attorney representing the FDA.Earlier this year, Vale and his attorneys failed to convince the court that Hon. John Gleeson, judgeof the Eastern District Court of New York and attorney Charles Kleinberg should be dismissed onConstitutional grounds, that Vale should be provided a bill of particulars and that certain statementsmade in civil deposition should be dismissed on Constitutional grounds.Undaunted, Vale told ICHF that "I know there will be victory and I love fighting. The Good Lordhas let me fight a good fight."A legal defends fund has been set up at www.seedoffaith.orgRelated articlesIS CANCER MERELY A VITAMIN DEFICIENCY DISEASE? Vitamin B17 Laetrile CancerTreatment Available in AustraliaCall for helpThe Nature of CancerHow does B17 Kill Cancer?The Medical MafiaMorris Fishbein - AMA Enemy Of American HealthSpeaking out against the Cancer industryThe Politics of Cancer TherapySentencing Delay In Vale Case Involving Criminal ContemptJason Vale has the following message:Dear Friends and Family,The jury we begin deliberating again on Monday morning. The court house is at 225 Cadman PlazaEast, Brooklyn, N.Y. 11201. Please pray. Sunday morning starts the fast until the jury is out. Somewill go until the jury comes back with a verdict and some will fast only for Sunday. I need your511

prayer as does the many that will be helped after the Lord gives the victory. He has delivered mefrom death, surely He will deliver me from this situation. The Battle is the Lord's!Prayer1. That the jury's mind is protected from all the influence of the govt.2. That ministering angels, minister to them along with the Holy Spirit for revelation during theirdeliberation.3. That the Lord turn the heart of Judge Gleeson. He told me straight out at a side bar that apricotseeds were a scam and that I was taking advantage of vulnerable cancer victims. He was bias fromthe beginning for certain reasons. This made it very difficult during trial. I have seen apricot seedsstop cancer in every single case from prevention to stage two. After stage two cancer more intensehealth therapy is needed. At the site apricotsfromgod.org you can read more about it.4. That this situation is used to bring God the glory and healing to the nation.5. For strength and faithJason David, ValeJason Vale and the Cancer MafiaFrom:http://www.laleva.org/eng/2004/02/jason_vale_and_the_cancer_mafia.htmlJason Vale, a former arm wrestling champion who cured his cancer with natural means and who felt heshould help others cure themselves as well, has run afoul of - the Cancer Mafia.Vale was tried and is awaiting sentencing - expected for March 5, 2004 - for violating an FDA order tocease selling apricot seeds and any extract from them such as laetrile, while promoting them as a cure forcancer.The FDA's approach practically makes treatment with laetrile or vitamin B 17 illegal, because nopharmaceutical company can make enough money selling them to make it worth going through theregistration process. As we see, the pharmaceutical monopoly on disease is eliminating a cure that is notin its financial interest.Why is Laetrile Treatment Illegal ?Why doesn't the whole world know about this ?The Answer : $ money $(The original article with some further links is here)Because the pharmaceutical multinationals are unable to patent or claim exclusive rights to the vitaminB17, as it is derived from a natural source (The Prunus Amygdalis Rosacea family), the multinationalpharmaceuticals launched and have continued to launch attacks of unprecedented vicious propaganda512

against B17 despite the hard proof of its effectiveness in controlling all forms of cancer which is availablein overwhelming abundance.The cancer industry is a $200 Billion a year industry. That's right not $200 million but $200 BILLION!!!Now if you had a large interest in such a huge market wouldn't you try to protect your industry and marketshare? Of course you would. And that's exactly what has happened and is happening today. Unfortunatelywe find ourselves living in a time where lies and deceit have been and are being used by governmentnational bodies and foundations which were designed to research cures and treatments for cancer, not tofocus on protecting their significant financial interest.Did you know the wealthiest non profit institution on this planet is the American Cancer Society ?Did you know the worlds largest private cancer center Sloan-Kettering Memorial Hospital (SKMH) wasestablished by Wall Streets top Banks and Corporations including a large interest from the Rockefellers. Intoday's society do the major corporations and banks place people before profit? Of course not!! Every dayour newspapers in Australia tell us a story where our Banks and major corporations are putting profitbefore people.Did you know that the major generous donators and financial contributors to the Sloan-Kettering MemorialHospital include all the major chemical companies that actually supply the chemotherapy and drugs usedto treat patients at the hospital !Companies such as Bristol Myers spend over $1 billion dollars annually on cancer research to improve orintroduce new chemo drugs. Bristol Myers supplies over half the worlds chemotherapy drugs. So they havea significant interest in the cancer industry. So significant is their interest that the board members thatchair the largest cancer drug and chemical companies also chair or are board members of all the majorcancer institutes. Funny that, one would think there is a conflict of interest here. They get around thissimply by either not taking a salary or making it a voluntary position with the cancer centres. After all,the chemical companies pay them more than enough for being board members of the chemical companiesthemselves. For example Paul A Marks who is president and CEO of the Sloan-Kettering Memorial Hospitaland is also Director of Pfizer which manufactures chemotherapy and cancer related drugs.Also James Robinson is a board member of the Sloan-Kettering Memorial Hospital and also a Director ofBristol Myers one of the largest suppliers of cancer chemotherapy and other cancer drugs. You will findmost of the executives that chair or are board members of all the top cancer organizations also chair orare affiliated with one or more of the major cancer drug multinationals. As mentioned, they get aroundthis conflict of interest most of the time by not taking a salary from either the research center or the drugcompany. Either way its a huge conflict of interest in my view.This is why the Sloan-Kettering Memorial Hospital (SKMH), National Cancer Institute (NCI), AmericanCancer Society (ACS), Food and Drug Administration (FDA) & the American Medical Association (AMA) areinvolved together to ensure they persecute and squeeze out any threats to their market. Even if it costsmillions of lives and even if the therapy works, if its a threat they will stamp it out...513

It is scary to know that the very government regulatory agencies themselves, such as the US Food & DrugAdministration and Britain's Medicines Control Agency, which are supposed to protect the public frompotentially dangerous products coming onto the market are horribly compromised because of ties with thechemical/drug industries that make cancer drugs.A USA TODAY analysis of financial conflicts at 159 FDA advisory committee meetings from 1st January -30th June 2000 found that at 55% of their meetings, more than half of the FDA advisors had conflicts ofinterest!!!These cancer organizations are run by business leaders, bankers and board members of the cancer drugcompanies that supply chemotherapy drugs to the market. Because many of today's known carcinogens areby-products of profitable industries of which these same board members have financial interests in, theiraim is to prevent cancer preventions and prevent any natural or non chemical therapy from entering themarket. It’s a perfect Cartel between these giants of big business. John Reed a director of SKMH is also adirector of tobacco giant Philip Morris.For example... The way the current system is setup thanks to the FDA and AMA, did you know it now costsover $100 million to develop a new drug in America. They have literally setup a monopoly situation. It’s apoker game and the ante is $100 million if you want to play.In 1982 Dr Richard Crout of the FDA made his agency's position very clear: "I never have and never willapprove a new drug to an individual, but only to a large pharmaceutical firm with unlimited finances".The problem here is the processing of Laetrile cannot be patented. It’s a natural product. you can't makemillions or huge profits like cancer drugs generate. As Edward G Griffin puts it "So no substance fromnature will ever be legally available for cancer unless its source can be monopolized. No matter how safeand effective it may be, and no matter how many people may have benefited, it will forever berelegated to the category of unproven therapies making them illegal to prescribe, to promote and touse".Laetrile and all other natural products, used in treating cancer are a threat to their profits.SEE also earlier articles on Vale's battle with the FDAAnother:http://www.laleva.org/eng/2004/02/in_defense_of_the_cancer_industry.html514

ALLEGATED 13Hazards of CaMV PromoterJoe Cummins - Dept. of Plant Sciences, University of Western Ontario, Ontario,CanadaMae-Wan Ho and Angela Ryan, Department of Biological Sciences, OpenUniversity, Walton Hall, Milton Keynes, MK7 6AA(To appear in Nature Biotechnology April 2000)This is a rebuttal to an article in Nature Biotechnology (Jan. 2000) attacking an earlier article, nowpublished (Ho, M.W., Ryan, A., Cummins, J. (1999) The cauliflower mosaic viral promoter – arecipe for disaster? Microbial Ecology in Health and Disease 11, 194-197).Keywords, CaMV 35S promoter, horizontal gene transfer, precautionary principle, hazardsof GM cropsIn your account (Jan. 2000) (1) of our pre-publication manuscript, you quote the criticisms butignore completely our full rebuttal, which was posted on the web last November. We shall outlinethe main points made in reply to the criticisms. The full details and references are available on ourwebsite (2).Our manuscript (3) reviews and synthesizes the scientific literature on the 35S promoter of thecauliflower mosaic virus (CaMV) used to give constitutive over-expression of transgenes inpractically all GM crops already commercialized or undergoing field trials. The promoter functionsefficiently in all plants, as well as green algae, yeast and E. coli. It has a modular structure, withparts common to, and interchangeable with promoters of other plant and animal viruses. It also hasa recombination hotspot, flanked by multiple motifs involved in recombination, similar to otherrecombination hotspots including the borders of the Agrobacterium T DNA vector most frequentlyused in making transgenic plants. The suspected mechanism of recombination – double-strandedDNA break-repair - requires little or no DNA sequence homologies. Finally, recombinationbetween viral transgenes and infecting viruses has been demonstrated in the laboratory (4).The findings suggest that transgenic constructs with the CaMV 35S promoter may be structurallyunstable and prone to horizontal gene transfer and recombination. The potential hazards aremutagenesis, carcinogenesis, reactivation of dormant viruses and generation of new viruses. Theseconsiderations are especially relevant in the light of recent findings that certain transgenic potatoes -containing the CaMV 35S promoter - may be unsafe for young rats, and that a significant part of theeffects may be due to "the construct or the genetic transformation (or both)" (5).Our critics believe the CaMV 35S promoter is not harmful because people have been eating thevirus in infected cabbages and cauliflower for many years. What we have been consuming ispredominantly intact virus and not naked viral genomes. Naked viral genomes have been found togive full-blown infections in non-host species that are not susceptible to the intact virus (6).Moreover, the 35S promoter in the CaMV is a stable, integral part of the virus, and cannot becompared to the 35S promoter in artificial transgenic constructs. Artificial constructs are well-515

known to be structurally unstable (7). We know that the 35S promoter in the virus does not transferinto genomes because pararetroviruses, such as CaMV, do not integrate into host genomes tocomplete their lifecycle; and viral replication takes place in the cytoplasm (8). But that says nothingabout the 35S promoter in transgenic constructs that are integrated into host genomes.Proviral sequences are present in all genomes, and as all viral promoters are modular, and have atleast one module – the TATA box - in common, if not more, it is not inconceivable that the 35Spromoter in transgenic constructs can reactivate dormant viruses or generate new viruses byrecombination. The CaMV 35S promoter has been joined artificially to the cDNAs of a wide rangeof viral genomes, and infectious viruses produced in the laboratory (9). There is also evidence thatproviral sequence in the genome can be reactivated (10).The fact that plants are "loaded" with potentially mobile elements can only make things worse.Most, if not all of the elements will have been ‘tamed’ in the course of evolution and hence nolonger mobile. But integration of transgenic constructs containing the 35S promoter may mobilizethe elements. The elements may in turn provide helper-functions to destabilize the transgenic DNA,and may also serve as substrates for recombination to generate more exotic invasive elements.In signing on to the International Biosafety Protocol in Montreal in January, more than 150governments agreed to implement the precautionary principle. The available evidence clearlyindicates that there are serious potential hazards associated with the use of the CaMV promoter. AllGM crops and products containing the CaMV promoter should therefore be withdrawn both fromcommercial use and from field trials unless and until they can be shown to be safe.References1. Hodgson, J. (2000). Nature Biotechnology 18, 13.2. Institute of Science in Society website: 3. Ho, M.W., Ryan, A. and Cummins, J. (1999). Microbial Ecology in Health and Disease , in press, andavailable in electronic form www.scup.no/mehd/ho;.4. Wintermantel, W. and Schoelz, J. (1996). Virology 223, 156-645. Ewen, S.W.B. and Pusztai, A. (1999). The Lancet 354, 1353-1354.6. See for example, Rekvig, O.P., et al (1992). Scand. J. Immunol. 36, 487-95.7. Structural instability of artificial vectors is a text-book topic. See Old, R.W. and Primrose, S.B. (1994).Principles of gene manipulation, 5th ed., Blackwell, Oxford.8. Covey, S., et al (1990). Proc. Nat. Acad. Sci. USA 87, 1633-7.9. Maiss, E., et al (1992). J. Gen. Virol. 73, 709-13; Meyer, M and Dessens, J. (1997). J. Gen. Viol. 78, 147-51.10. Nowora, T. et al (1999). Virology 255, 214-20.516

ALLEGATED 14Recent Evidence Confirms Risksof Horizontal Gene Transferby Mae-Wan Ho, Institute of Science in SocietySexually reproducing organisms pass their DNA only “vertically,” from one generation to the next.But bacteria and viruses exchange bits of DNA “horizontally,” from one organism to another. Whathappens when artificially introduced genes get transferred horizontally? Mae-Wan Ho of theInstitute of Science in Society summarizes the evidence.The oft-repeated refrain that “transgenic DNA is just like ordinary DNA” is false. Transgenic DNAis in many respects optimized for horizontal gene transfer. It is designed to cross species barriersand to jump into genomes, and it has homologies to the DNA of many species and their geneticparasites (plasmids, transposons and viruses), thereby enhancing recombination with all of them. [1]Transgenic constructs contain new combinations of genes that have never existed, and they alsoamplify gene products that have never been part of our food chain. [2]The health risks of horizontal gene transfer include:• Antibiotic resistance genes spreading to pathogenic bacteria;• Disease-associated genes spreading and recombining to create new virusesand bacteria that cause diseases;• Transgenic DNA inserting into human cells, triggering cancer.The risk of cancer is highlighted by the recent report that gene therapy—genetic modification ofhuman cells—claimed its first cancer victim. [3] The procedure, in which bone marrow cells aregenetically modified outside the body and re-implanted, was previously thought to avoid creatinginfectious viruses and causing cancer, both recognized major hazards of gene therapy.The risk of cancer is highlighted by the…report that gene therapy—genetic modificationof human cells—claimed its first cancer victim.The transgenic constructs used in genetic modification are basically the same whether it is of humancells or of other animals and plants. An aggressive promoter from a virus is often used to boost theexpression of the transgene—in animal and human cells from the cytomegalovirus that infectsmammalian cells, and in plants the 35S promoter from the cauliflower mosaic virus (CaMV) thatinfects Cruciferae plants.Unfortunately, although the CaMV virus is specific for plants, its 35S promoter is active in speciesacross the living world, human cells included, as we discovered in the scientific literature datingback to 1989. Plant geneticists who have incorporated the promoter into practically all GM cropsnow grown commercially are apparently unaware of this crucial information. [4]517

In 1999, another problem with the CaMV 35S promoter was identified: it has a “recombinationhotspot” where it tends to break and join up with other DNA. [5] Since then, we have continued towarn our regulators that the CaMV 35S promoter will be extra prone to spread by horizontal genetransfer and recombination [6–8]. The recent controversy over the transgenic contamination of theMexican landraces [9] hinges on observations suggesting that the transgenic DNA with the CaMV35S promoter is “fragmenting and promiscuously scattering throughout the genome” of thelandraces, observations that would be consistent with our expectations. [10]Research results released early in 2002 by the Food Standards Agency [11] indicate that transgenicDNA from GM soya flour, eaten in a single hamburger and milk shake meal, was found transferredto the bacteria in the gut contents from the colostomy bags of human volunteers.…although the CaMV virus is specific for plants, its 35S promoter is active in speciesacross the living world…The Agency dismissed the findings and downplayed the risks. The comments, “it is extremelyunlikely that genes from genetically modified (GM) food can end up in bacteria in the gut of peoplewho eat them,” and “the findings had been assessed by several Government experts who had ruledthat humans were not at risk,” are seriously misleading.First the experimental design stacked the odds heavily against finding a positive result. Forexample, the probe for transgenic DNA covered only a tiny fraction of the entire construct. So onlya correspondingly tiny fraction of the actual transfers would ever be detected, especially given thewell-known tendency of transgenic constructs to fragment and rearrange.Second, there was no attempt to check for transgenic DNA in the blood and blood cells, althoughscientific reports dating back to the early 1990s indicated transgenic DNA could pass through theintestine and the placenta, and become incorporated into the blood cells, liver and spleen cells andcells of the foetus and newborn. [12]The observation in the FSA report [13] that no transgenic DNA was found in the faeces of the“healthy volunteers,” far from being reassuring, raises the worrying possibility that the transgenicDNA has all been taken up into the intestinal cells and/or passed into the bloodstream.Research results…indicate that transgenic DNA from GM soya flour, eaten in a singlehamburger…was found transferred to the bacteria in the gut…Third, no attempt was made to address the limitations of the detection method and the scope of theinvestigation failed completely in assessing the real risks. False assurances were made that “humanswere not at risk.”Another research project on horizontal gene transfer commissioned by the Ministry of Agriculture,Fisheries and Food (MAFF), the predecessor to the Food Standards Agency, concernsAgrobacterium tumefaciens, the soil bacterium that causes crown gall disease, which has beendeveloped as a major gene transfer vector for making transgenic plants. Foreign genes are typicallyspliced into T-DNA—part of a plasmid called Ti (tumour-inducing)—that’s integrated into plantgenome.bh.518

It turns out that Agrobacterium injects T-DNA into plant cells in a process that strongly resemblesconjugation, i.e., mating between bacterial cells, and all the necessary signals and genes involvedare interchangeable with those for conjugation [14].That means transgenic plants created by the T-DNA vector system have a ready route for horizontalgene escape, via Agrobacterium, helped by the ordinary conjugative mechanisms of many otherbacteria that cause diseases. [14]A report submitted to MAFF in 1997 had indeed raised the possibility that Agrobacteriumtumefaciens could be a vector for gene escape [15, 16]. The researchers found that it was extremelydifficult to get rid of the Agrobacterium.…transgenic plants created by the T-DNA vector system have a ready route forhorizontal gene escape, via Agrobacterium, helped by the ordinary conjugativemechanisms of many other bacteria that cause diseases.High rates of gene transfer are known to be associated with the plant root system and thegerminating seed. [17] Agrobacterium could multiply and transfer transgenic DNA to otherbacteria, as well as to the next crop plant. Agrobacterium was also found to transfer genes intoseveral types of human cells [18], and in a manner similar to that which it uses to transform plantcells.All the risks of horizontal gene transfer described above are real, and far outweigh any potentialbenefits that GM crops can offer. There is no case for allowing any commercial release of GMcrops and food products.The following experiments and tests should be done to address the risks of horizontal genetransfer:1. Feeding experiments similar to those carried out by Dr. Arpad Pusztai’s team should be done,using well-characterized transgenic soya and/or maize meal feed, with full, adequate monitoring fortransgenic DNA in the faeces, blood and blood cells, and post-mortem histological examinationsthat include tracking transfer of transgenic DNA into the genome of cells. As an added control,nontransgenic DNA from the same GM feed sample should also be monitored.2. Feeding trials on human volunteers should be carried out using well-characterized transgenicsoya and/or maize meal feed, with full, adequate monitoring for transgenic DNA in the faeces,blood and blood cells. Also as an added control, nontransgenic DNA from the same GM feedsample should also be monitored.3. The stability of transgenic plants in successive generations should be systematically investigated,especially for those containing CaMV 35S promoter, using adequate quantitative moleculartechniques.519

4. Full molecular characterization of all transgenic lines must be carried out to establish uniformityand genetic stability of the insert(s).5. All transgenic plants created by the Agrobacterium T-DNA vector system should be tested for thepersistence of the bacteria and vectors. The soil in which they have been grown should also bemonitored for gene escape to soil bacteria. And the potential for horizontal gene transfer to the nextcrop via the germinating seed and root system should be carefully monitored.References and Notes1. Ho MW, Horizontal Gene Transfer. The Hidden Hazards of Genetic Engineering, TWNBiotechnology Series, Third World Network, 2001 (available fom the ISIS online storehttp://www.i-sis.org.uk/onlinestore.php#books); also Mae-Wan Ho, Horizontal gene transfer andgenetic engineering, SCOPES website, AAAS, 2000.2. Ho MW, Briefing to the Rt. Hon. Michael Meacher, Minister for the Environment on the SpecialSafety Concerns of Transgenic Agriculture and Related Issues (http://www.isis.org.uk/meacher99.php).April 1999 , published in Seminario Internacional sobtre Direcito daBiodiversidade, Revista cej: Centro de estudos Judiciarios do Conselho da Justica Federal, Brasil,pp.120–6, 1999.3. Science, News of the Week, 4 October 2002; see also Ho MW, Predicted hazard of gene therapya reality, ISIS Report, October 2002 (http://www.i-sis.org.uk/PHGT.php).4. Ho MW, GM maize approved on bad science in the UK, Science in Society 2002, 15(http://www.i-sis.org.uk/isisnews/sis15.php), 10–25.5. Kohli A., Griffiths S, Palacios N, Twyman R, Vain P, Laurie D and Christou P. Molecularcharacterization of transforming plasmid rearrangements in transgenic rice reveals a recombinationhot spot in the CaMV 35S promoter and confirms the predominance of microhomology mediatedrecombination” Plant.J. 1999, 17,591–601.6. Ho MW, Ryan A and Cummins J. Cauliflower mosaic viral promoter—a recipe for Disaster?Microbial Ecology in Health and Disease 1999 11, 194–7.7. Ho MW, Ryan A. and Cummins J., Hazards of transgenic plants with the cauliflower mosaicviral promoter. Microbial Ecology in Health and Disease 2000, 12, 6–11.8. Ho MW, Ryan A and Cummins J., CaMV35S promoter fragmentation hotspot confirmed and it isactive in animals. Microbial Ecology in Health and Disease 2000, 12, 189.9. Quist D. and Chapela IH., Transgenic DNA introgressed into traditional maize landraces inOaxaca, Mexico. Nature 2001, 414, 541–3, 2001.10. Ho MW, Astonishing denial of transgenic contamination, Science in Society 2002, 15, 13–14(http://www.i-sis.org.uk/isisnews/sis15.php).520

11.Netherwood T, Martin-Orue SM, O’Donnell AG, Gockling S, Gilbert HJ and Mathers JC.,Transgenes in genetically modified Soya survive passage through the small bowel but arecompletely degraded in the colon. Technical report on the Food Standards Agency projectG010008, Evaluating the risks associated with using GMOs in human foods–University ofNewcastle.12. Doerfler, W. and Schubbert, R. (1998). Uptake of foreign DNA from the environment: thegastroinestinal tract and the placenta as portals of entry, Wien Klin Wochenschr. 110, 40–44.p. 40.13. Ferguson GC and Heinemann JA. Recent history of trans-kingdom conjugation. In HorizontalGene Transfer 2nd ed. (ed. M Syvanen & CI Kado), pp 3–17, Academic Press, San Diego, 2002.14. Ho MW. What’s unspeakable in horizontal gene transfer? Heredity (in press); Ho MW,Averting sense for nonsense, Science in Society 2002, 16, 29–30.15. McNicole et al (1997) The Possibility of Agrobacterium as a Vehicle for Gene Escape. MAFF.R&D and Surveillance Report: 395 (http://www.i-sis.org.uk/isisnews/sis16.php).16. Barrett et al (1997). A risk assessment study of plant genetic transformation usingAgrobacterium and implications for analysis of trangenic plants. Plant Cell Tissue and OrganCulture 47: 135–144.17. Sengelov G, Kristensen KJ, Sorensen AH, Kroer N, and Sorensen SJ. Effect of genomiclocation on horizontal transfer of a recombinant gene cassette between Pseudomonas strains in therhizosphere and spermosphere of barley seedlings. Current Microbiology 2001, 42, 160–7.18. Kunik T, Tzfira T, Kapulnik Y, Gafni Y, Dingwall C, and Citovsky V., Genetic transformationof HeLa cells by Agrobacterium. PNAS USA, 2001, 98, 1871–87; also, Common plant vectorinjects genes into human cells, ISIS News 2002, 11/12, p. 10 (http://www.i-sis.org.uk/isisnews/isisnews11.php).This article can be found on the I-SIS website at http://www.i-sis.org.uk/FSAopenmeeting.phpCONTACT DETAILS The Institute of Science in Society, PO Box 32097, London NW1 OXR;telephone: [44 20 8731 7714] [44 20 7383 3376] [44 20 7272 5636]; general inquiries: sam@isis.org.uk;mailing list: press-release@i-sis.org.uk; ISIS director: m.w.ho@i-sis.org.uk521

ALLEGATED 15OGM crops increase pesticidesby Niccolo Sarno — last modified 2008-02-07A new report shows that planting genetically modified (GM) crops is causing an increased use of harmful pesticides inmajor biotech crop producing countries.MEDIA ADVISORY : Friends of the Earth InternationalNew report: OGM crops increase pesticide useIn 2007 GM crops still failed to tackle hunger and poverty in developing countriesBRUSSELS (BELGIUM), LAGOS (NIGERIA), KUALA LUMPUR (MALAYSIA) – February 13, 2008 – A newreport released on February 13 th shows that planting genetically modified (GM) crops is causing an increased use ofharmful pesticides in major biotech crop producing countries. [1]The 2008 edition of the Friends of the Earth International “Who Benefits from GM crops?” report series is titled “TheRise in Pesticide Use” and concludes that GM crops on the market today have on the whole caused an increase ratherthan a decrease in toxic pesticides use, and have failed to tackle hunger and poverty. [2]After more than a decade of GM crop cultivation, more than 70% of the area cultivated with biotech crops is stillconcentrated in only two countries: the US and Argentina. To date, GM crops have done nothing to alleviate hunger orpoverty in Africa or elsewhere.“The biotech industry is telling Africans that we need GM crops to tackle the food needs of our population. But howcan we believe such statements when the majority of GM crops are used to feed the animals of rich countries, produceindustrial products like agrofuels, and overall don’t yield more than conventional crops?”, said Nnimmo Bassey ofFriends of the Earth Nigeria/ERA.“GM crops still fail to deliver the long-promised benefits. They are not good for the environment, as they areincreasing pesticide use. In addition, they do not benefit small farmers or consumers in terms of quality or price,” addedBassey.The new report launch coincides with the annual release of the “Global Status of Commercialized Biotech” report ofthe industry-sponsored International Service for the Acquisition of Agri-biotech Applications (ISAAA) which promotesGM crops as beneficial for the environment and a key solution to hunger and poverty.The GM crops industry continues to misleadingly claim that GM crops reduce pesticide use and play a role in tacklingpoverty and hunger. The main conclusions of the 2008 report “The Rise in Pesticide Use” include :1) GM crops are not ‘green’. The adoption of Roundup Ready (RR) crops, the most extensively grown GM crop today,has led to an increase in pesticide use:- In the United States, data from the U.S. Department of Agriculture (USDA) shows that RR crops drove a more than15-fold increase in the use of glyphosate –the herbicide associated with RR crops- on major field crops from 1994 to2005. In 2006, the last year for which data is available, glyphosate use on soybeans jumped a substantial 28%. Theintensity of glyphosate use has also risen dramatically. From 1994 to 2006, the amount of glyphosate applied per acre ofsoya rose by more than 150%.The increase in glyphosate herbicide is no longer displacing other herbicides in the US. From 2002 to 2006 the use of2,4-D –one of the most widely used herbicide in the world- on soybeans more than doubled, and the use of atrazine (anherbicide banned in Europe due to links to health problems) on corn increased by 12 per cent from 2002 to 2005.522

- In major RR soybean producer countries, like Brazil and Argentina, glyphosate use and weed resistance have risen. A2007 study by a Brazilian governmental agency shows that the use of glyphosate increased 79,6% between 2000 to2005, much faster than the expansion in area planted with RR soya. In 2007 a glyphosate-resistant weed called JohnsonGrass infested over 120,000 ha in Argentina. An estimated 25 million litres of herbicides other than glyphosate will beneeded, resulting in increasing production costs of between $160 to 950 million per year. In India, a 2007 study fromAndhra University concluded that Bt cotton uses the same amount of pesticides as conventional cotton.2) GM crops do not tackle hunger or poverty. Most GM crops commercialized so far are destined for animal feed, notfor food, and none have been introduced to address hunger and poverty issues. GM crops are not providing help tosmall farmers in developing countries. In South Africa, for example since the adoption of Bt cotton, the number ofsmall cotton farmers have plummeted from 3229 in 2001/02 to just 853 in 2006/07.3) Overall, current GM crops do not yield more than other existing crop varieties:- RR Soybeans, the most widely planted GM crop in the world, does not have a higher yield performance thanconventional soya. On the contrary, many studies show that RR soya has on average 5-10% lower yield than equivalentconventional varieties.- Bt cotton does not have higher yields than conventional cotton. In most countries where Bt cotton was adopted -suchas the U.S., Argentina, Colombia, and Australia – overall cotton yields remained constant . In other countries, like Indiaand China, the yield increase is mainly due to weather conditions and other production factors not related to GMtechnology. For example Xinjiang, the Chinese province with the highest cotton production and the highest averageyield in China, grows mostly conventional cotton, not Bt varieties.FOR MORE INFORMATION CONTACT:- AFRICA: Nnimmo Bassey, Friends of the Earth Nigeria, Tel: +234 8037274395 (mobile) or +234 52602680 (office)- ASIA: Nizam Mahshar, Friends of the Earth Malaysia, Tel: +60 194777755- EUROPE: Helen Holder, Friends of the Earth Europe in Brussels: +32 474 857 638 or +32 2 542 01 82- NORTH AMERICA: Bill Freese, Center for Food Safety, United States, Tel: +1 202 (547) 9359- SOUTH AMERICA: David Cardozo, Friends of the Earth Paraguay, Tel: +595 981 445067NOTES TO EDITORS:[1] DOCUMENTS AVAILABLE ONLINE:A Question and Answer document on GM crops and the Millennium Development Goals of halving hunger and povertyby 2015 is available at:http://www.foeeurope.org/GMOs/Who_Benefits/QA_FINAL_FEB08.pdfThe executive summary of the report is available online athttp://www.foei.org/en/publications/pdfs/gmcrops2008execsummary.pdf/The executive summary of the report is available IN SPANISH online at:http://www.foei.org/es/publications/pdfs/gmcrops2008execsummary.pdf/The executive summary of the report is available IN FRENCH online at:http://www.foei.org/fr/publications/pdfs/gmcrops2008execsummary.pdf/The full report is available online at http://www.foei.org/en/publications/pdfs/gmcrops2008full.pdf/[2] Previous editions of the ‘Who Benefits from GM crops’ series are online at:http://www.foei.org/en/campaigns/gmo/publications523

ALLEGATED 16American Academy of Environmental Medicine (AAEM) :a Moratorium on Gentically Manipulated (GMO) FoodAmy Dean (D.O) and Jennifer Armstrong (M.D.)(22/5/2009)According to the World Health Organization, Genetically Modified Organisms (GMOs) are “organisms in which thegenetic material (DNA) has been altered in such a way does not occur naturally ( 1 ).This technology is also referred to as “genetic engineering”, “biotechnology” or “recombinant DNA technology” andconsists of randomly inserting genetic fragments of DNA from one organism to another, usually from a differentspecies. For example, an artificial combination of genes that includes a gene to produce the pesticide Cry1Ab protein(commonly known as Bt toxin), originally found in Bacillus thuringiensis, is inserted in to the DNA of corn randomly.Both the location of the transferred gene sequence in the corn DNA and the consequences of the insertion differ witheach insertion. The plant cells that have taken up the inserted gene are then grown in a lab using tissue culture and/ornutrient medium that allows them to develop into plants that are used to grow GM food crops ( 2 ).Natural breeding processes have been safety utilized for the past several thousand years. In contrast, “GE croptechnology abrogates natural reproductive processes, selection occurs at the single cell level, the procedure is highlymutagenic and routinely breeches genera barriers, and the technique has only been used commercially for 10 years”( 3 ).Despite these differences, safety assessment of GM foods has been based on the idea of “substantial equivalence” suchthat “if a new food is found to be substantially equivalent in composition and nutritional characteristics to an existingfood, it can be regarded as safe as the conventional food” ( 4 ). However, several animal studies indicate serious healthrisks associated with GM food consumption including infertility, immune dysregulation, accelerated aging,dysregulation of genes associated with cholesterol synthesis, insulin regulation, cell signalling, and protein formation,and changes in the liver, kidney, spleen and gastrointestinal system.There is more than a casual association between GM foods and adverse health effects. There is causation as defined byHill’s Criteria in the areas of strength of association, consistency, specificity, biological gradient, and biologicalplausibility ( 5 ). The strength of association and consistency between GM foods and disease is confirmed in severalanimal studies ( 2,6,7,8,9,10,11 ).Specificity of the association of GM foods and specific disease processes is also supported. Multiple animal studiesshow significant immune dysregulation, including upregulation of cytokines associated with asthma, allergy, andinflammation ( 6,11 ).Animal studies also show altered structure and function of the liver, including altered lipid and carbohydratemetabolism as well as cellular changes that could lead to accelerated aging and possibly lead to the accumulation ofreactive oxygen species (ROS) ( 7,8,10 ).Changes in the kidney, pancreas and spleen have also been documented ( 6,8,10 ). A recent 2008 study links GM corn withinfertility, showing a significant decrease in offspring over time and significantly lower litter weight in mice fed GMcorn ( 8 ).This study also found that over 400 genes were found to be expressed differently in the mice fed GM corn. These aregenes known to control protein synthesis and modification, cell signaling, cholesterol synthesis, and insulin regulation.Studies also show intestinal damage in animals fed GM foods, including proliferative cell growth and disruption of theintestinal immune system ( 6 ).Regarding biological gradient, one study, done by Kroghsbo, et al., has shown that rats fed transgenic Bt rice trended toa dose related response for Bt specific IgA ( 11 ).524

Also, because of the mounting data, it is biologically plausible for Genetically Modified Foods to cause adverse healtheffects in humans.In spite of this risk, the biotechnology industry claims that GM food can feed the world through production of highercrop yields. However, a recent report by the Union of Concerned Scientists reviewed 12 academic studies and indicatesotherwise: “The several thousand field trials over the last 20 years for genes aimed at increasing operational orintrinsic yield (of crops) indicate a significant undertaking. Yet none of these field trials have resulted in increased yieldin commercialized major food/feed crops, with the exception of Bt corn” ( 12 ). However, it was further stated that thisincrease is largely due to traditional breeding improvements.Therefore, because GM foods pose a serious health risk in the areas of toxicology, allergy and immune function,reproductive health, and metabolic, physiologic and genetic health and are without benefit, the AAEM believes that it isimperative to adopt the precautionary principle, which is one of the main regulatory tools of the European Unionenvironmental and health policy and serves as a foundation for several international agreements ( 13 ).The most commonly used definition is from the 1992 Rio Declaration that states: “In order to protect the environment,the precautionary approach shall be widely applied by States according to their capabilities. Where there are threats ofserious or irreversible damage, lack of full scientific certainty shall not be used as a reason for postponing costeffectivemeasures to prevent environmental degradation” ( 13 ).Another often used definition originated from an environmental meeting in the United States in 1998 stating : “When anactivity raises threats to the environment or human health, precautionary measures should be taken, even if some causeand effect relationships are not fully established scientifically. In this context, the proponent of an activity, rather thanthe public, should bear the burden of proof (of the safety of the activity) “ ( 13 ).With the precautionary principle in mind, because GM foods have not been properly tested for human consumption, andbecause there is ample evidence of probable harm, the AAEM asks :1. Physicians to educate their patients, the medical community, and the public to avoid GM foods whenpossible and provide educational materials concerning GM foods and health risks.2. Physicians to consider the possible role of GM foods in the disease processes of the patients they treatand to document any changes in patient health when changing from GM food to non-GM food.3. Our members, the medical community, and the independent scientific community to gather casestudies potentially related to GM food consumption and health effects, begin epidemiological researchto investigate the role of GM foods on human health, and conduct safe methods of determining theeffect of GM foods on human health.4. For a moratorium on GM food, implementation of immediate long term independent safety testing,and labelling of GM foods, which is necessary for the health and safety of consumers. (This statementwas reviewed and approved by the Executive Committee of the American Academy of EnvironmentalMedicine on May 8, 2009)Submitted by Amy Dean, D.O. and Jennifer Armstrong, M.D.525

Bibliography1. World Health Organisation (INTERNET). (2002) Foods derived from modern technology:20 questions on genetically modified foods. Available from:http://www.who.int/foodsafety/publications/biotech/20questions/en/index.html2. Smith JM.: Genetic Roulette. Fairfield: Yes Books.2007. p.103. Freese W.: Safety testing and regulation of genetically engineered foods. Biotechnology andGenetic Engineering Reviews. Nov. 2004. pp.: 214. Society of Toxicology. The safety of genetically modified foods produced throughbiotechnology. Toxicol. Sci. 2003; 71: pp.: 2-85. Hill A.B.: The environmental and disease: association or causation ? ; Proceeding of theRoyal Society of Medicine, 1965; 58, pp.: 295-3006. Finamore A.: Intestinal and peripheral immune response to MON 810 maize ingestion inweaning and old mice; J. Agric. Food Chem. 2008; 56 (23) , pp: 11533-115397. Malatesta M.: A long-term study on female mice fed on a genetically modified soybean:effects on liver ageing. Histochem. Cell. Biol. 2008, 130, pp.: 967-9778. Velimirov A.: Biological effects of transgenic maize NK603xMON810 fed in long termreproduction studies in mice. Report-Federal Ministry of Health, Family and Youth. 20089. Ewen S., Pustzai A.: Effects of diets containing genetically modified potatoes expressingGalanthus nivalis lectin on rat small intestine, Lancet, 354, pp.: 1353-135410. Kilic A.: A three generational study with genetically modified Bt corn in rats: biochemicaland histopathological investigation, Food Chem. Toxicol., 2008, 46(3), pp: 1164-117011. Kroghsbo S.: Immunotoxicological studies of genetically modified rice expression PHA-Electin in or Bt toxin in wistar rats, Toxicology, 2008, 245, pp: 24-3412. Gurain-Sherman D. : 2009. Failure to yield: evaluating the performance of geneticallyengineered crops. Cambridge (MA) : Union of Concerned Scientists.13. Lofstedt R.: The precautionary principle: risk, regulation and politics, Meron College,Oxford, 2002FRANCAIS : OGM mise en garde de AAEML’American Academy of Environmetal Medicine (AAEM) vient juste de publier un appel en faveurd’un moratorie immediat sur la nourriture genetiquement modifieehttp://www.mondialisation.ca/index.php?context=va&aid=13709http://aaemonline.org/pressrelease.html526

ALLEGATED 17SANA Conference – Bologna 2008, 13 th SeptemberPromoted by: AAM Terra NuovaScientific coordination: Studio AgernovaGiuseppe Nacci, Giuseppe Altieri“The Threat of GMOs (Genetically Modified Organisms) onalimentary models accompanying the immune and detoxifyingtherapy”Cancer is a degenerative disease caused by a lack of vitamins and poisoning from chemicalsubstances present in food.One can estimate the number of vitamins and pro-vitamin substances present in natural plantscommonly used as food by humans as more than 13,000 – 15,000 types.The introduction into modern agriculture of Genetically Modified Organisms (GMOs) is anunjustified and very dangerous alteration of what Evolution has produced in plants over hundreds ofmillions of years:plants on which the subsequent biochemical evolution of superior complex animal organisms hasbeen based, culminating with the advent of mammals in the last 65 million years and then with thearrival of Man.Therefore the delicate biochemical balance of the human race depends on plant species remainingintegral, just as evolution created them, because the health of every one of us is based on thebiochemical human cell, and this depends, through the complexity of the DNA, on the use ofthousands of vitamins and of the herbal-chemical compounds present in nature.527

Plants are complex organisms as well, they are the fruit of hundreds of millions of years ofbiological evolution:every genetic modification caused in plants by Man (with radiation such as Chernobyl, orwith retroviruses such as presently used in GMO), however small that modification is, willcause damage, irreparable damage which often cannot be seen, because man only knows alimited number of safe vitamins and pro-vitamin substances.However, there are tens of thousands of vitamins and other substances present in plants, andit is these which are responsible for the correct working of the biochemical human complexand the human genome (DNA).To (supposedly) achieve greater agricultural production today we resort to changing the genetic patrimony of naturalplants, with the aim of:1) changing their structure,2) making them sterile (thus farmers have to buy new seeds every year),3) patenting the transformation induced and4) re-selling the thus obtained product all over the world.Actually it has never been demonstrated that GMO cultivations produce a larger amount of products. In fact, someindependent scientific studies carried out by ISIS proved quite the opposite.Furthermore it can be affirmed that there is a substantial equivalence between:1) the genetically modified product (GMO)2) and that obtained by selecting genetic characteristics (that is by means of naturally crossbreeding plants as has beendone by man over the course of thousands of years).However, this “substantial equivalence” cannot be sustained because:1) the natural crossbreeding of plants uses natural seeds of the same species, while genetic manipulation (GMO)crosses all barriers, and introduces genes from other types of vegetable species or even bacteria, viruses andanimal genes.2) in fact the majority of genes used in genetic engineering come from living species which have never been apart of the human food chain and actually come from DNA not of plants but of animals, bacteria or virusesand/or transgenic retroviruses.EIGHT immediate threats can therefore be identified:FIRST POINT: The impoverishment of vitamin and pro-vitamin complexes in the plantsSECOND POINT: genetic mutations of plants and the subsequent alteration of human biochemistryTHIRD POINT: the failure of the anti-cancer dietFOURTH POINT: diseases induced by transgenic virusesFIFTH POINT: intoxication by poisons synthesized from transgenic plants528

SIXTH POINT: danger of worldwide famine due to “TERMINATOR” technologySEVENTH POINT: transgenic pollution of natural plantsEIGHTH POINT: the irreversible disappearance of the genetic inheritance of natural plantsFIRST POINT OF THE THREAT OF GMOs:The impoverishment of vitamin and pro-vitamin complexes in the plantsThe deliberate attempt to deactivate the natural substances contained in the plants is very serious: in this way fresh fruitand vegetables – greatly impoverished of many vitamins – can be carried over long distances and long periods of timebecause their oxidation does not take place.These vitamins are able to enter into complex enzymatic mechanisms inside mammals’ DNA, inducing theAPOPTOSIS (suicide) phenomenon in these mammal cells if they are suffering from infections or above all CANCERor LEUKAEMIA.This deliberative vitamin impoverishment will ensure commercial profits and represents a serious act of deliberatedamage inflicted on the Ecosystem by means of GMOs.Fresh plants contain thousands of vitamins which are able to activate our immune system againstgerms, viruses or tumour cells, or even to induce apoptosis (cell suicide or programmed cell death)in tumour cells.Amounts of vitamins needed to induce apoptosis in a certain number of tumour cells in thelaboratory without damaging healthy human cells are really very small.Several studies from medical and scientific literature, almost all in PDF format, show the actualability of these vitamins to induce APOPTOSIS in the cancerous cell line considered. Amountsneeded are measurable in:micromoles (i.e. micromoles/litre, i.e. nanomoles/millilitre, i.e. picomoles/microlitre).SEE: http://www.erbeofficinali/dati/nacci/allpdf.php from chapter 6 of the e-book “Thousand Plants against Cancerwithout Chemo-Therapy” http://www.thenhf.com/about_us.html; http://www.mednat.org/cancro/nacci_english.pdf(“Plants which make Cancers suicide”)SECOND POINT OF THE THREAT OF GMOs:Genetic mutations of plants and the subsequent alteration of humanbiochemistryBecause of the introduction of foreign genes (for example from animals, bacteria, viruses and retroviruses) into theDNA of plants, an alteration in the normal genomic sequence of the plant occurs, with the appearance of new proteinsand/or the loss of other proteins of a genomic sequence.529

Therefore new substances similar to natural vitamins have appeared, but which actually have enzymatic andbiochemical characteristics different to natural ones, and therefore introduce changes in their component of biochemicalactivity on the human genome, once they have been introduced through food.There is therefore the potential risk of new diseases of an “artificial” type, caused by the geneticmanipulation (GMO) of vegetable organisms, genetically polluted by new vitamin-like moleculeswith inductive effects on the human DNA and on its complex biochemistry which are totallyunknown, but probably heralding serious damage given the extreme complexity and hencevulnerability of the human DNA.For example, the only test on a long-term basis (24 months) carried out by an Italian research group demonstrated thatGMOs may modify some internal organs. Feeding mice with the famous maize Roundup Ready changed the structureand the functioning of their liver, pancreas and testicles cells. (Malatesta M.: Fine structural analyses of pancreaticacinar cell nuclei from mice fed on GM soybean. Eur. J. Histochem., 47: 385-388, 2003;http://www.mednat.org/alimentazione/Malatesta.pdf),A second study was conducted by Pusztai: he found out that mice fed with transgenic potatoesshowed damage to organs, thickening of the small intestine and scarce brain development. Potatoeswere genetically modified in order to contain lectin, which makes plants resistant to pesticides.(Pusztai: Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat smallintestine, The Lancet Vol. 354, October 16, 1999) (http://www.mednat.org/alimentazione/Pusztai.pdf),A third study was carried out by Prescott, who analysed GMO peas (Prescott: Transgenic expression of bean-amylaseinhibitor in peas results in altered structure and immunogenicity, J. Agric. Food Chem., 53, (23), pages: 9023-9030,2005.http://www.mednat.org/alimentazione/Prescott.pdf.A fourth study was made by Dr Irina Ermakova in Russia, at the Institute of Higher Nervous Activity andNeurophysiology of the Russian Academy of Sciences (RAS) in Moscow.http://eco-irina-ermakova.narod.ru/eng/index.htmTHIRD POINT OF THE THREAT OF GMOs:The failure of the anti-cancer dietAs already demonstrated by Gerson (www.gerson.org) and other authors, many substancescontained only in fruit and biologically grown raw vegetables are able to induce the IMMUNECASCADE against tumours, detoxification and the particular phenomenon of apoptosis (suicide) ofdiseased cells making it unnecessary to conduct difficult and expensive research.153 patients suffering from the worst form of cancer known (melanoma) followed Dr Gerson’s anti-cancer diet, andafter 5 years the percentage of recovery varied from:70-90% (if the tumour was localized)to 40-70% (if the tumour had metastasized),provided that the patients had not previously undergone chemotherapy.Hildebrand, G.L.: Five year survival rates of melanoma patients treated by diet therapy after the manner of Gerson: aretrospective review, in Alternative Therapies, vol.1 [4], September 1995, pages 29-37).530

www.gerson-research.org/docs/HildenbrandGLG-1996-1/index.htmlOn the contrary, using chemotherapy the percentage of recovery from melanoma after 5 years is 6% or – according toother sources – is zero per cent.Morgan G.: The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies, Clinical Oncol., 2004,16, pages: 549-560 http://www.mednat.org/cancro/MORGAN.PDFIn the latest study of MORGAN, based on more than 270,000 patients undergoing CHEMOTHERAPY, this zerosurvival value is confirmed even in the case of:cancer of the pancreas,sarcoma,womb cancer,cancer of the prostate,bladder cancer,kidney cancer,and multiple myeloma.This percentage goes up to 1% in case of:stomach and colon cancer,about 2% in case of breast or lung cancer,3-5% in case of rectum cancer,4-5% in case of brain cancer,5% in case of esophagus cancer,9% in case of ovary cancer,10% in case of NON-Hodgkin lymphoma,12% in case of cervical cancer,about 40% in case of testicular cancer and Hodgkin lymphoma.The explanation of the effectiveness of these vegetarian diets lies in:not consuming food containing all the potential factors which promote cell growth,in particular AVOIDING the simultaneous consumption (1-3 hours) of ALL 9 essential amino acids(Valin, Isoleucin, Leucin, Lisin, Metionin, Hystidine, Tryphtophan, Phenylalanine, Treonine).These should not be taken simultaneously as through them cancer cells can build PROTEINS, i.e. other ill cells.The intake of the following substances must also be avoided:nucleic acids,vitamin B12 andfolic acid.(as they cause the DNA replication of the cancer cell)531

In the past,…before the GMO Era, this rule was very simple to respect:the foods which contained all of these were of animal origin (meat, fish, eggs, yeast, milk, cheese, butter…).Both Gerson and other authors (including Chinese and Indian medicine) forbade the consumption of these foods for atleast a year.A vegetarian diet, based only on fruit and vegetables, cereals and legumes, was, thus, the winning diet.However, cereals and legumes are rich in ESSENTIAL AMINO ACIDS and thus their use in cancer therapy by manyother Western, Chinese and Indian schools of natural medicine might seem surprising.The success of these therapies, which are so distant from each other as far as the THEORY is concerned but are sosimilar in the effectiveness against CANCER, can be explained by the modern BIOCHEMISTRY:NO CEREALS and NO LEGUMES, taken singularly,contained ALL 9 essential amino acids.These foods, however, if consumed together at the same meal determined the assimilation of all 9 amino acids.The human body can thus synthesize PROTEINS and build cells – cancer cells.Comparing these new therapies, it is clear thatit is ABSOLUTELY FORBIDDEN to eat CEREALS + LEGUMES together,i.e. pasta (or polenta, or bread [even if unleavened] or rice) + legumes,because according to the modern BIOCHEMISTRY there would be the integration of the 9 essential amino acids(8 of them are contained in cereals and the other one, i.e. Lisin, is contained in legumes)(8 of them are contained in legumes and the other one, i.e. Metionin, is contained in cereals)with a similar nutritional effect as that obtained from eating meat(after all, once a plate of pasta and beans was called … “poor man’s meat”).Today, however, because of the introduction on the market of cereals, legumes and other vegetables which have beengenetically modified (GMO), many of these foods contain ALL the essential amino acids (Day P.R.: Geneticmodification of plants: significant issues and hurdles success, Am.J.Clin.Nutr., 63(4), pp.: 651S-656S, 1996http://www.mednat.org/alimentazione/DAY.pdf), effectively rendering cancer NO LONGER curable in the way it isdescribed in this study and according to the therapy of Gerson and many other authors.FOURTH POINT OF THE THREAT OF GMOs:diseases induced by transgenic virusesThe transgenic viruses with which genetically modified organisms (GMO) are created today enterinto the DNA of the plant, modifying it in a way which is unknown to us.532

These viruses are supposed to lie dormant but there is nothing to prevent them from reactivatingthemselves in a manner similar to the well known RNA tumour viruses (Oncornaviruses) or DNAtumour viruses (both inducers of leukaemias, sarcomas, carcinomas, gliomas...).These viruses can also be the carriers of new diseases or diseases similar to syndromes whosedynamics are unfortunately very little understood (AIDS, Mad Cow Disease, etc…), and whoseorigin is still very vague (perhaps transgenic viruses?).There is ample bibliography on viruses used in GMOs.(SEE chapter 8 of the E-Book “Thousand Plants against Cancer without Chemo-Therapy”http://www.thenhf.com/about_us.html; http://www.mednat.org/cancro/nacci_english.pdf):It is well known that CaMV (Cauliflower Mosaic Virus) is used today in the replication of retroviruses introduced in theplants by GMO multinationals in order to modify their DNA (GMO plants).This virus is active both in angiosperms and gymnosperms, i.e. in all plants.This virus is used by GMO multinationals to modify genetically plants because it contains particular promoters, whichare “motors” which drive genetic activation.CaMV has two promoters: 19S and 35S.Of these two the 35S promoter is most frequently used by multinationals.The 35S promoter is a DNA sequence of about 400 bases (units of genetic sequence of four different molecules:Adenine, Cytosine, Guanine or Thymine).The CaMV promoter is preferred above other potential promoters used by GMO multinationals to modify plantsbecause it is not influenced by the different conditions of vegetable cell tissue types and thus it can act.Unfortunately it is able to penetrate and replicate in animal cells, including mammalian and human cells, asdemonstrated by Vlasak in a study published in 2003. Vlasak J.: Comparison of hCMV immediate early and CaMV 35Spromoters in both plant and human cells, Journal of Biotechnology No. 103, pages: 197-202, 2003)http://www.dirittolibertadicura.org/images/OGM/vlasak.pdfhttp://www.mednat.org/alimentazione/vlasak.pdfThese artificial pararetroviruses are created and used by multinationals to modify the DNA of plants. They are similar toretroviruses already present in nature, such as:HIV retrovirus of AIDS,HUMAN LEUKAEMIA retrovirus,Hepatitis B retrovirus(Bonneville: Retrovirus, Viroids and RNA recombination, RNA Genetics, Vol. 11, pages: 23-42, 1988).According to scientific literature, CaMV is closely related to the virus of human hepatitis B and AIDS.(Doolitte: Quart. Rev. Biol. 64, 2, 1989); (Xiong and Eickbush, Origin and evolution of retroelements based upon theirriverse transcriptase sequences EMBO Journal 9, pages 3353, 1990)(Doolitte: Quart.Rev.Biol. 64, 2, 1989) ; (Xiong and Eickbush, Origin and evolution of retroelements based upon theirriverse transcriptase sequences EMBO Journal 9, pp. 3353, 1990http://www.mednat.org/alimentazione/EMBO%20JOURNAL%201990.pdf )533

Using CaMV in plants eaten by humans and/or animals can be very dangerous and hazardous because of the GENETICRECOMBINATION of DNA chromosomes in the plants. This can lead to the recombination of the 35S promoter itselfwith the DNA of the person or animal that has eaten fruit, vegetables, pasta or GMO soya containing thesepararetroviruses.Through GENETIC RECOMBINATION, the viruses can also include cell genes present in the animal that haspreviously eaten that GMO plant. These can reach the man who has eaten that animal causing totally unknown geneticeffects.One the most likely consequences is the outbreak of cancers and leukaemias.Genetic modifications to progeny can be another consequence.In these cases, the DNA system would be disrupted as happens in the case of exposure to ionizing radiations.However, differently from ionizing radiations, there would be also the risk of new infectious diseases.NEW INFECTIOUS DISEASES: it has been demonstrated that the CaMV genes incorporated into the plant (canola)chromosomes recombine with infecting viruses to produce new, much more virulent diseases.This experimental model concerning the safety of transgenic plants containing viral genes such as CaMV was presentedby GAL in a study published in 1992:Gal S.: Agroinfection of transgenic plants leads to viable Cauliflower Mosaic Virus by intermolecular recombination,Virology, No.187, pages: 525-533, 1992 http://www.dirittolibertadicura.org/images/OGM/gal.pdfhttp://www.mednat.org/alimentazione/Gal.pdfAbout recombination between CaMV and viruses involving the promoter see also Vaden’s paper published in 1990:Ray Vaden: Recombination sites in Cauliflower Mosaic Virus DNAs; implications for Mechanisms of recombination,Virology, No.177, pages: 717-726, 1990 http://www.dirittolibertadicura.org/images/OGM/ray%20vaden%20.pdfhttp://www.mednat.org/alimentazione/Ray%20Vaden%20.pdfOther scientific studies demonstrated that recombination of these retroviruses may take place either between DNA andDNA or RNA and RNA, thus creating new viral infections.(Mol.Plant-Microbe Interactions 5, 48, 1992).Similar related experiments suggest that altered plants may cause deadly diseases, as shown by Greene in 1994:Greene A.E.: Recombination between viral RNA and transgenic plant transcripts, Science, Vol. 263, 11 march 1994http://www.dirittolibertadicura.org/images/OGM/greene.pdfhttp://www.mednat.org/alimentazione/Greene.pdfVery dangerous viral DNA chains produced by normal RNA viruses are frequently propagated in the vegetableenvironment (GMO plants) using the CaMV 35S promoter to drive the production of RNA viruses which otherwisecould not propagate in the plant DNA. From here they could pass to the animal DNA (man included) or in the bacteriaor viruses DNA.Boyer J.C.: Infectious transcripts and cDNA clones of RNA Viruses, Virology, No. 198, pages: 415-426, 1994http://www.dirittolibertadicura.org/images/OGM/boyer.pdf; http://www.mednat.org/alimentazione/Boyer.pdf534

In conclusion: promoters recombine with the infecting viruses to produce virulent new diseases.CaMV viruses and its promoters 19S and 35S may incorporate genes from the host plant or animal or bacterium DNA –or even from a DNA virus – creating virulent new diseases.In case of a DNA virus, CaMV can recombine with insect DNA viruses, thus propagating in the insect cells.(Zuidema D.: J.Gen.Vir. 71, pages 312, 1990).http://www.mednat.org/alimentazione/zuidema.pdfAs a consequence, it is likely that by eating tomatoes genetically modified with CaMV (recombined for example withhepatitis B viruses) a large number of people could create a SUPERVIRUS able to propagate in plants commonly usedas food and in insects – such as mosquitoes – and then reach the man.Allison R.F.: Recombination in plants expressing viral transgenes, Seminars in Virology, Vol. 7, pages: 417-422, 1996http://www.dirittolibertadicura.org/images/OGM/allison.pdf; http://www.mednat.org/alimentazione/Allison.pdfWintermantel W.M.: Isolation of recombinant viruses between Culiflower Mosaic Virus and a viral gene in transgenicplants under conditions of moderate selection pressure, Virology, No. 223, pages: 156-164, 1996http://www.dirittolibertadicura.org/images/OGM/wintermantel.pdfhttp://www.mednat.org/alimentazione/Wintermantel.pdfLatham J.: GM Gene Flow (B): Horizontal gene transfer of viral inserts from GM plants to viruses, Technical paper,February 2004J.T.Dessens: Cauliflower mosaic virus 35S promoter-controlled DNA copies of cowpea mosaic virus RNAs areinfectious on plants, Journal of General Virology, No.74, pages: 889-892, 1993http://www.mednat.org/alimentazione/dessens.pdfSteinbrecher R.A.: The CaMV 35S Promoter Government and Corporate Scientific incompetence: failure to assess thesafety of GMO crops, Econexus Briefing, December 2002Mae Wan Ho: The CAMV 35S Promoter fragmentation hotspot confirmed, and it is active in animals, MicrobialEcology in Health and Disease 2000, 12, págs: 189http://www.mednat.org/alimentazione/MaeWanHo1.pdfMae Wan Ho: Cauliflower Mosaic Viral Promoter – a recipe for disaster, Microbial Ecology in Health and Disease1999, 11, pp: 194-197http://www.mednat.org/alimentazione/MaeWanHo2.pdfThere are some natural retroviruses which are able to cause leukaemia, lymphomas,sarcomas or breast cancer in animals and human beings (from chapter 8 of the book“Thousand Plants against cancer without Chemo”.)They are very dangerous and a casual recombination with the promoter 35S ofCauliflower Mosaic Virus is very likely to happen once GMO plants are introduced inthe animal or/and human diet.Search for GMO retroviruses in human tumoursIt is the author’s view that research should be conducted in patients suffering from tumour, to check any possiblehybridation between the polysomal RNA (of suspected GMO viral origin, probably related to the modifiedOncornavirus used in GMO plants to produce food) obtained from human tumours of patients who have eaten GMO535

food, and the DNA created in laboratory with reverse transcriptase from Oncornaviruses which have been modified toproduce GMOs.Note: all this, however, requires access to restricted, maybe patented information on retrovirus models used by GMOmultinationals and modifications they made before putting GMO plants on the market.It is much more difficult to find the specific tumour DNA viruses used by GMO multinationals to modify the DNA ofcommonly eaten plants, since these DNA viruses (Poxviruses, Herpesviruses, Papovaviruses, Adenoviruses) –differently from GMO Oncornaviruses – cannot be found in the serum or in the urine of patients.It has nevertheless been demonstrated that a very specific and small part of messenger-RNA remains in the cytoplasmof mammalian tumour cells infected and modified by these tumour DNA viruses. This part of messenger-RNA does notexist in normal cells nor in tumour cells infected with other DNA viruses.It is necessary, then, to verify the possible hybridation between this RNA-messenger – of suspected GMO viral origin,i.e. produced by a DNA virus modified to produce GMO foods – obtained from the cytoplasm of tumour cells inpatients who have eaten GMO food, and the DNA created in laboratory with the same DNA viruses modified toproduce GMOs.Also in this case, access to restricted, maybe patented information on retrovirus models used by GMO multinationalsand modifications they made before putting GMO plants on the market is needed.If the hybridation takes place, thus creating a radioactive ( 32 P) hybrid DNA, it will show the presence of viral DNAsequences in the modified cells (Green, Perspect Biol. Med., 1978).Secret informationNowadays multinationals are spreading “classified” GMOs all over the world, whose modificationis not known as is protected by industrial secrecy.Not having this information, no analyses and controls are possible.This is a matter of grave concern as these GMOs are produced in the USA and in other countrieswhere they are not kept separate from GMO-free products and so the exportations can becontaminated.What should be done?First of all, it is necessary to ask the Istituto Superiore di Sanità (Italian Health Institute), the IstitutoZooprofilattico (Animal Disease Control Centre) in Rome, the Ministry of Agriculture and theEuropean Commission for information and launch a parliament enquiry.The European Commission is favouring the authorization of GMO foods in Europe, in order toavoid a complete block of importations from the USA.It amounts to say since GMOs are in any case imported secretly, it is better to accept them inEurope so that maybe they can be controlled…But a stronger political action in virtue of the precaution principle of Maastricht Treat is very likelyto prevent GMOs from being licensed and any industrial “secrets” about genetic manipulationsfrom being hidden.536

In fact this “secret” information could regard not only the imported products but also theseeds…thus causing an irreversible and indiscriminate contamination of the European agriculture.FIFTH POINT OF THE THREAT OF GMOs:intoxication by poisons synthesized from transgenic plantsChronic poisoning of foods caused by the toxic substances in insecticides which are used on plants to make themresistant to parasites such as Bacillus touringiensis, with a likely consequent increase in cancers, miscarriages, geneticmutations in descendants, Acquired Immunodeficiency Syndromes, degenerative diseases and diseases caused by toxicsubstances, etc.For example, it has been demonstrated that GMO maize causes lesions in the oral cavity of sheep and ruminants.A study published in 2003 showed that eating GMO maize damages the oral cavity wall and is associated withinexplicable death in experiment animals: sheep and ruminants.Duggan et al, Fate of genetically modified maize DNA in the oral cavity and rumen of sheep, British Journal ofNutrition, 89 (2): 159-166, 2003 http://www.mednat.org/alimentazione/Duggan_GMO_Mais.pdfSIXTH POINT OF THE THREAT OF GMOs:danger of worldwide famine due to “TERMINATOR” technologyPassing to natural “indigenous” species of wheat, rice, sweet corn, potatoes, legumes, because vegetables themselvescannot reproduce themselves the normal way due to “TERMINATOR” technology; this is caused by cross pollination,and it also causes irreversibly the loss of natural vegetables that are nowadays used as food by humans, as these will bepolluted by the transgenic genes coming from transgenically cultivated areas (GMO) where “TERMINATOR”technology is used.Therefore there is a potential menace of global famine in the future, something that cannot be controlled, as the worldwill not have sufficient quantities of wheat, rice, sweet corn, legumes, the way they are in nature, or in any case not ofthe “NON-TERMINATOR” kind.SEVENTH POINT OF THE THREAT OF GMOs:transgenic pollution of natural plantsThe transmission to “indigenous” natural species of artificial toxic substances such as Bacillus touringiensis or othersby means of cross pollination, with a potential threat also to the plants and herbs used today in herbal remedies, becausethe latter will also become polluted by the transgenic genes coming from the agricultural areas devoted to transgeniccultivation (GMO).537

EIGHTH POINT OF THE THREAT OF GMOs:the irreversible disappearance of the genetic inheritance of natural plantsThe gradual and irreversible disappearance of biological diversity, that is of the normal, natural flora. This phenomenonis already taking place in the USA as a consequence of modern cultivation practises, which prefer transgenicmonoculture (GMO) to differentiated cultivation techniques. Transgenic cultivation will pose a serious threat to thoseareas which are rich in biodiversity (natural genomes): the transgenic flow which will go from modified plants tonatural plants will be inevitable when the numerical ratio between areas cultivated with artificial plants exceeds theareas of natural plants, thus causing the irreversible loss of a great part of the natural genetic patrimony of all the plantsexisting in the world: at present there are about 442,000 species already classified out of an estimated total of 600,000 –800,000 species.In short:Numerous plants have already disappeared during the last few years because farmers have abandoned natural plants toadopt artificial plants, that is, genetically modified plants, because they are uniform in their genome and they yield highproduction (but are poor in vitamins). They are intrinsically sick (because they are incapable of surviving withoutpesticides), they are made sterile for economic reasons, and finally they are genetically manipulated to resist to insectsand other animals because they themselves are capable of producing poisons, i.e. toxic substances which are eaten byfarmyard animals and so passed on to man.Even in the forests genetic variety is threatened today by the loss of habitat, not only caused by incorrect deforestationpractices, but also by the contamination of the genetic patrimony (which has adapted to local situations) by hybridscreated by large seed companies which produce GMOs.Transgenic products per se therefore aim at underlining the unilaterality of monocultures, which lead to thedisappearance of the natural genetic inheritance existing from hundreds of millions of years.In a not so distant future, all the varieties of plants – used as food or not – which are typical of a region or country willnot exist any more.Environmental genetic contamination induced by hybrids created by large companies producing GMO seeds – whichinevitably will cross with varieties present in nature – will cause the irreversible loss of the natural genetic inheritanceand of all particular features gained by the plant genome during the long processes of adaptation to the differentenvironmental situations.Even natural environments such as forests are seriously threatened by this loss. Substantially the very foundations of thehuman Biochemistry – the human DNA – are threatened today by the reckless use of these artificial plants, without anypossibilities of regaining a genetic inheritance of more than 440,000 classified species out of 600,000-800,00 estimatedspecies. Most of these will disappear within few hundred years because of genetic damage caused by man.Agro-alimentary Multinationals (GMO, Biotech)For some years we have been witnessing the birth of multinationals which define themselves as “science of lifemultinationals”, which are active in the pharmaceutical market, agri-business (seeds and pesticides) and the veterinarybusiness.They are, in themselves, different sectors, but they are linked by the use of biotechnology (GMO) to produce theirproducts.These multinationals are using unscrupulous and aggressive economic strategies: since the beginning of the 90s theyhave been working towards buying companies, even large companies.538

One of these, Monsanto, within the space of a few years has acquired Asgrov, Agracetus, De Calb, and Cargillinvesting 10 billion euros.Another big group, Dupont, has acquired Pioneer, investing about 8 billion Euros.These investments do not seem to have any economic logic: they pay much more for the companies than their actualvalue, as if they were trying to eliminate a potential competitor rather than obtain a short term economic result.Alongside the acquisitions we also have the mergers: Ciba Geigy and Sandoz created Novartis (with a turnover of 20billion euros in the year 1997-98).From the merger of the French company Rhone Poulenc and the German company Hoechst we have the new companyAventis.Still within this context, Syngenta, the first worldwide agrochemical group was founded in October 2000. It is the resultof a merger between the Swiss company Novartis (a company well-known for producing medicines for chemotherapy)and the Anglo-Swedish company Astra-Zeneca (a company also well-known for producing medicines forchemotherapy), and will have a turnover of about 8 billion euros. Monsanto, after its merger with Pharmacia & Upjohn,a large pharmaceutical industry (this too is well-known as a producer of medicines for chemotherapy) now concernsitself only with agriculture, with a turnover which in 2000 reached 5.5 billion dollars.The current situation stands thus: a few multinationals (Syngenta, Monsanto, Novartis, Dupont and Aventis) have 25-30% of the seed market (but more than 90% of the transgenic seed market) and behind these big groups there is aplethora of smaller companies which makes one think that this trend can only get stronger in the future, since mediumsize companies cannot compete with these big groups. The objective seems clear: to convert the traditional seed marketinto a biotechnical one, i.e. GMO. But the worrying fact is that we find the same names in the field of pesticides, wherethe same companies control 55% of the market, and in the pharmaceutical field where the same companies play adominant role.Chemical-pharmaceutical Multinationals (Big-Farma)The history of the chemical-pharmaceutical multinationals is incredible because of their rapid development, and todaythey are connected to the agro-alimentary sector in an extremely dangerous way.The chemical-pharmaceutical industry started in Europe in the second half of the nineteenth century: in many cases theywere dyeing industries which, moving away from basic chemistry, moved towards the new and more promising fieldsof specialized chemistry in key economic fields.Before the Second World War, a powerful international pharmaceutical cartel developed in Germany. It controlledglobal pharmaceutical companies and chemical plants and was active in 93 countries, representing a powerful economicand political force in each of them. It was known as I.G. Farben.It would become the main supporter of Hitler’s chemical production during the years of war, offering products such ashigh explosives, toxic gases and the ignominious Zyklon-B, the lethal substance used by Nazis in the death camps.In 1928, however, before the outbreak of war, the American monopolist manufacturer John D. Rockfeller had mergedhis international empire in America with I.G. Farben, creating the largest and most powerful pharmaceutical cartel everseen.The Military Nuremberg Tribunal established in 1946/47 that the Second World War would not have taken placewithout this petrochemical cartel called I.G. Farben.As a consequence of the sentence passed by the Tribunal, I.G. Farben was divided into Bayern, BASF and Hoechst, andsome executives were condemned for initiating a war against international law, genocide, the exploitation and looting ofprivate and public properties in foreign countries and other crimes against humanity.The events leading to the war and linked to this powerful cartel are reported in Joseph Borkin’s The Crime andPunishment of IG Farben.539

After the war, Germany, with its three large companies Bayer, Hoechst and BASF (which encouraged the rise of Hitler’snational socialism), played an important role. So did Switzerland, which, in Basle, saw the founding and thedevelopment of companies Ciba, Sandoz and Roche – all of which later spread throughout the world.But it was in the 1990s that the really big mergers started: in 1989, in the United Kingdom two big pharmaceuticalcompanies merged to form Smith Kline-Beecham: later they merged with American Home (with an annual turnover ofabout 25 billion euros).In 1993 the Swedish company Pharmacia bought the Italian company Farmitalia-Carlo Erba, then it merged with theAmerican company Upjohn in 1995, and then again with Monsanto, before being bought by Pfizer which hadpreviously bought the American company Parke Davis.In 1995 there was the Glaxo-Wellcome merger (with an annual turnover of about 14 billion euros).In 1998 Smith-Kline-Beecham (with an annual turnover of 62 billion euros) merged with Glaxo-Wellcome (with anannual turnover of about 90 billion euros) to make an annual turnover of more than 150 billion euros.In the meantime the English company Imperial Chemical Industries merged with the Swedish company Astra, formingthe company Astra-Zeneca.These mergers have continued among the same companies operating in the same field: Sandoz and Ciba Geigy(Novartis, 1996), Astra-Zeneca (1998).These huge companies have not been founded for the good of patients but out of the need to create monopolies andhence ever bigger profits.Latest data:June 2002: Aventis was taken over by Bayer. This allowed Bayer to enter the sector of GMO seeds. The merger broughtto the foundation of Bayer CropScience, which is composed of three main commercial groups: Crop Protection, BioScience and Environmental Science.June 2005: Sementis was taken over by Monsanto.The perverse allianceOne can thus affirm that the two cardinal points of the economy and the life of the individual, agriculture andpharmaceuticals, are substantially under the control of a few multinational groups.CONCLUSIONSWe are faced with a choice: accepting biochemical modifications of plantsleading to immense damage to human health or taking a stand togetherwith the democratic institutions of our society against GMO and chemopharmaceuticalmultinationals, which in their perverse alliance areresponsible for the reckless invasion of GMOs all over the world.The solution is simple but there are only four months left to prevent GMOsfrom causing an IRREVERSIBLE event, as Prof Altieri rightly defined it:1) Total ban on GMO cultivation540

2) Total ban on experiments in the fields (risk of horizontal genetictransfer)3) Promotion of organic farming (it produces a higher yield)4) Defence of bio-diversity, in particular with the re-establishment ofthe freedom to exchange seeds.If this does not take place, the world will need to consider the possibilityof a SECOND NUREMBERG TRIALS…Thank you541

ALLEGATED 18SANA (Bologna) 13 /9 / 2008Aprobado por: AAM Terra NuovaCoordinamiento Científico: Studio AgernovaGiuseppe Nacci y Giuseppe Altieri“La amenaza OMG(Organismos Modificados Genéticamente)en los modelos alimenticios de acompañamiento a laterapia inmunitaria y desintoxicante”El Cáncer es una enfermedad degenerativa que se debe a carencia de vitaminas eintoxicaciones de sustancias químicas presentes en la comida.Las vitaminas y las provitaminas presentes en las plantas naturales que se usan en laalimentación humana común se pueden estimar en un número superior a 13.000-15.000 tipos.La introducción en la agricultura moderna de los Organismos ModificadosGenéticamente (O.M.G.) no tiene justificación y resulta ser una alteración muypeligrosa de lo que la evolución ha producido en las plantas durante más de cientomillones de años: son plantas sobre las que se ha basado la sucesiva evoluciónbioquímica de los complejos organismos animales superiores, culminados con lallegada de los Mamíferos en los últimos 65 millones de años y luego con la llegadadel Hombre.Por lo tanto, el delicado equilibrio bioquímico de la especie humana depende de laintegridad de las especies vegetales así como la Evolución las ha traído hastanosotros, porque la Salud de todos nosotros se basa sobre la Bioquímica celularhumana y ésta depende, en su propia complejidad genómica (ADN), del uso de milesde vitaminas y de compuestos fitoquímicos presentes en la Naturaleza.La planta también es un organismo complejo, fruto de la evolución biológica demillones de años: cada modificación genética provocada por el Hombre (porradiaciones como pasó en Chernóbil, o con retrovirus como actualmente pasa con losOMG), producirá en todo caso un daño, daño irreparable que a menudo no podrá serreconocido, porque el Hombre conoce con seguridad sólo a pocas decenas devitaminas y de otras provitaminas.542

Viceversa, las vitaminas y las demás sustancias contenidas en las plantas son decenasde millones y son las responsables del correcto funcionamiento de la complejabioquímica humana y del genoma humano (ADN).Hoy en día, para obtener la ventaja de una (supuesta) mayor producción agrícola, serecurre al método de modificar el patrimonio genético de las plantas naturales, para:1) modificar su estructura,2) convertirlas en estériles (para obligar los agricultores a comprar nuevassemillas cada año),3) patentar la transformación inducida,4) vender en todo el mundo el producto que se obtiene.En realidad nunca se ha llegado a demostrar que los cultivos OMG producen mayorescantidades de productos, sino menores, como se demuestra en las obras científicasindependientes redactas por el Instituto británico ISIS.Se afirma además que existe una substancial equivalencia entre:1) el producto modificado genéticamente (OMG)2) el producto obtenido con la selección de los caracteres genéticos (o sea,mediante el cruce natural de plantas como la naturaleza hace desde siempre enel curso de millones de años).Nosotros afirmamos sin embargo que la “equivalencia substancial” es absolutamenteinsostenible, porque:1) el cruce natural de plantas ocurre con semillas naturales de la misma especie,mientras que la manipulación genética (OMG) ocurre sobrepasando lasbarreras de especies vegetales o, incluso, bacterias, virus o animales.2) Es por ese motivo que la mayor parte de los genes usados por la ingenieríagenética provienen de especies vivientes que nunca han formado parte de laalimentación humana o incluso provienen de ADN que no pertenecen aplantas, sino a animales, bacterias o virus y/o retrovirus transgénicos.Es posible entonces distinguir OCHO amenazas inmediatas:PRIMERO: pérdida de los complejos provitamínicos y vitamínicos de las plantas543

SEGUNDO: mutaciones genéticas de las plantas y consecuente alteración de labioquímica humanaTERCERO: fracaso de la dieta-anti-cáncerCUARTO: enfermedades inducidas por virus transgénicosQUINTO: intoxicación causada por venenos sintetizados desde plantas transgénicasSEXTO: posibles carestías a nivel mundial por causa de la tecnología“TERMINATOR”SEPTIMO: modificación transgénica de plantas naturalesOPTAVO: desaparición irreversible del patrimonio genético de las plantas naturales544

PRIMER PUNTO DE LA AMENAZA OMG:Pérdida de los complejos provitamínicos y vitamínicos de las plantasEn efecto, es gravísimo el intento deliberado de desactivar las substancias naturalescontenidas en las plantas para hacer posible el transporte en largas distancias ydurante tiempos muy largos de fruta y de verduras frescas en realidad empobrecidasde muchas vitaminas, cuya ausencia permite evitar la oxidación de tales comidas.Sin embargo las vitaminas entran en complejos mecanismos enzimáticos del ADN delos mamíferos e inducen el fenómeno de la APOPTOSIS (suicidio) en estas célulasde mamíferos si estas mismas están enfermas por causas infectivas o, sobre todo, deCÁNCER O LEUCEMIA.Ese fenómeno de deliberado empobrecimiento vitamínico, unicamente para laexplotación comercial es un acto gravísimo de daño deliberado infligido alecosistema mediante los OMG.Millones de vitaminas, contenidas en plantas frescas, son capaces de inducirfenómenos de activación de las defensas inmunitarias contra gérmenes, virus océlulas tumorales o incluso de provocar fenómenos de apoptosis (suicidio celular omuerte programada) en las mismas células tumorales.La cantidad de vitaminas necesaria para provocar en laboratorio la apoptosis de unacierta cantidad de células tumorales sin provocar algún daño a las células humanassanas es verdaderamente mínima.En muchas obras, casi todas en PDF, provenientes de literatura médico-científicaoficial, se indica la cantidad de vitaminas capaz de inducir el fenómeno de apoptosisen la específica línea celular neoplástica considerada, cantidad que se expresa en:micromol (o sea micromol/Litro, o sea nanomol/miliLitro,o sea picomol/microLitro).En efecto es gravísima la desaparición de muchas vitaminas naturales anti-cáncer(Antocianinas, Flavonoides, Polifenoles, sesquiterpene lactone Parthenolide, pentaacetilGeniposide, Camellina B, beta-Criptoxantina, Esperidina, Emodina, ácidoursólico, sulfuro de alilo, Eriodictoiolo, ácido protocatéquico, Indoli, Isotiocina,Resveratrol, Elemene, Acutiaporberina, Capsaicina, Wogonina, Fisetina, ácidocarnósico, Germanio sesquióxido, Epigallocatequina gallato, Limonene, Axeroftolopalmitato, alfa y beta Carotene, ácido trans-Retinoico, Tocoferoles, Cinaropicrina,Licopene, Proantocianidina, Damnacanthal, Baicalina, Baicaleina, ácidohidrocinámico, sesquiterpenoides como Atractilone o como Atractilenolides I, II, III,545

alcaloides del Gelsemio, otros flavonoides, Sinigrina, ácido ferúlico, ácido elágico,ácido cumarinico...) que inducen la apoptosis (suicidio) de los tumores.Para más información sobre el tema de la apoptosis, se vea el artículo en italiano“MECCANISMO DI APOPTOSI” en el capítulo 5 del libro in INTERNET “MillePiante per guarire dal Cancro senza Chemio” (http://www.medicinetradizionali.it/nacci.htmhttp://www.erbeofficinali.org/dati/nacci/index.php ; http://www.alternativemed.eu/cancro/1000%20piante_cancro.pdf ;http://www.mednat.org/Nacci%20libro.pdf ; http://www.medicinetradizionali.it/nacci.htm.Del sitio Internet http://erbeofficinali/dati/nacci/allpdf.php (o dewww.erbeofficinali.org/dati/nacci/tisaneantitum.php o de http://erbeofficinali.org) es posible bajarse gratisunos 100 artículos científicos en inglés sobre la apoptosis inducida por las vitaminasnaturales.Estas vitaminas están producidas por las plantas propiamente para protegerse devirus, bacterias y hongos cuando falta la protección química de los PESTICIDAS.Estas vitaminas dan “sabor” y “gusto” a la fruta y a la verdura biológica, conrespecto a la fruta y a la verdura tratada con pesticidas (fito-fármacos).Además de estas obras sobre las calidades anti cáncer de las vitaminas naturales queinducen el fenómeno del suicidio del cáncer, es oportuno entonces indicar datos debibliografía científica sobre las distintas modificaciones genéticas aportadas por lasMultinacionales OMG.Esta desaparición puede ocurrir a causa de la modificación genética de las plantas:por ejemplo, en el caso de la Pueraria species, es posible notar su riqueza enAntocianinas, que inducen la apoptosis de los tumores, pero en el caso de la Pueraria-GMO (modificada genéticamente por error), su contenido de Antocianinas se reducedel 40%. (Véase anexo “PUERARIA”: Joung JY.: An overexpression of chalcone reductase of Puerariamontana var. Lobata alters biosynthesis of anthocyanin and 5'-deoxyflavonoids in transgenic tobacco,Biochem Biopsys Res. Commun 2003, 303, págs.: 326-331.http://www.mednat.org/alimentazione/PUERARIA.pdf)En el trabajo de Woitsch y Romer de 2005 (Impact and interaction od liophilic antioxidants inmutants and transgenic plants, Journal of Plant Physiology, 162, 2005, págs: 1197-1209http://www.mednat.org/alimentazione/Nacci_Vitamins_in_GMO_Plants.pdf ) se demuestra además quefuera de los laboratorios, en las verdaderas condiciones ambientales de estrésclimático (oscilación térmica día-noche, viento, rayos solares ultravioletas, etc...) lasplantas OMG pierden la capacidad de producir vitaminas, aunque se hayan creado enlaboratorio propio para esta finalidad. La razón de tales fracasos es la total ignoranciade la Ciencia frente a la activación de complejos mecanismos bioquímicos dereparación que la planta tiene que actuar en condiciones de estrés ambiental de variasorígenes, a diferencia de las plantas naturales cuya evolución ha durado más de 500millones de años y se ha caracterizado por una natural y espontánea capacidad de546

producir decenas y decenas de vitaminas (algunas todavía desconocidas) paraprotegerse del estrés ambiental, de las radiaciones ultravioletas, de la oscilacióntérmica día-noche y de las infecciones virales, bacterianas o de hongos.Gravísima es la falta de semillas en los frutos OMG.La importancia de las semillas cono factores anti cáncer se debe a que contienen lafamosa vitamina B17 (se vea, por ejemplo, el trabajo del doctor “MORRONE” sobrediez pacientes americanos en 1962 – http://www.mednat.org/cancro/morrone.pdf – o el trabajo deldoctor Tasca de 1958 sobre 21 pacientes italianos – http://www.mednat.org/cancro/tasca.pdf – ytodo el capítulo 5 del libroin INTERNET “Mille Piante per guarire dal Cancro senza Chemio”(http://www.medicinetradizionali.it/nacci.htm http://www.erbeofficinali.org/dati/nacci/index.php ;http://www.alternativemed.eu/cancro/1000%20piante_cancro.pdf ; http://www.mednat.org/Nacci%20libro.pdf ;http://www.medicinetradizionali.it/nacci.htm ).Sin embargo, es muy grave la introducción por parte de las grandes empresas desemillas OMG en el mercado agrícola mundial de los mismos frutos sin semillas, enparticular de Cucumis melo, Citrus limonum, Citrullus vulgaris, Solanumlycopersicum, Vitis vinifera.547

SEGUNDO PUNTO DE LA AMENAZA OMGMutaciones genéticas de las plantas y alteración de la bioquímica humana.A causa de la introducción de genes extraños (por ejemplo de animales, bacterias,virus, retrovirus) en el ADN de la planta, se verifica en ella la alteración de la normalsecuencia genómica y comparecen nuevas proteínas y/o se pierden otras proteínas dela secuencia genómica.Han comparecido, además, nuevas sustancias similares a las vitaminas naturales, queen realidad tienen características de reactividad enzimática y bioquímica diferentes delas naturales, con inducción de modificación de su componente de actividadbioquímica sobre el genoma humano, una vez que se han introducido con laalimentación.Se denota la comparecencia de nuevas enfermedades nacidas de manera “artificial” acausa de la manipulación genética (OMG) de organismos vegetales, contaminadosgenéticamente por nuevas moléculas simil-vitamínicas con efectos inductivos sobreel ADN humano y sobre la compleja bioquímica del todo desconocida, pero queprobablemente anuncia graves daños dada la extrema complejidad y vulnerabilidaddel ADN humano.Por ejemplo, el único test a largo plazo (24 meses), conducido por un grupo deitalianos ha demostrado che los OMG pueden modificar algunos órganos internos. Lanutrición de los ratones con la famosa variedad de maíz Roundup Ready cambió laestructura y el funcionamiento de las células del hígado, del páncreas y de lostestículos. (Malatesta M.: Fine structural analyses of pancreatic acinar cell nuclei from mice fed on GMsoybean. Eur. J. Histochem., 47:385-388, 2003) http://www.mednat.org/alimentazione/Malatesta.pdfLa segunda obra que citamos es la de Pusztai: el autor descubrió que los ratonesalimentados con patatas transgénicas manifestaban daños a los órganos, espesamientodel intestino delgado y escaso desarrollo cerebral. Las patatas habían sidomodificadas genéticamente para contener lectina, para que las plantas se convirtieranresistentes a los pesticidas. (Pusztai: Effect of diets cointaining genetically modified potatoesexpressing Galanthus nivalis lectin on rat small intestine, The Lancet Vol. 354, October 16, 1999 :http://www.mednat.org/alimentazione/Pusztai.pdf)La tercera obra es la de Prescott sobre los guisantes-OMG :(http://www.mednat.org/alimentazione/Prescott.pdf)La cuarta obra es la de la doctora rusa Irina Ermakova, Institute of Higher NervousActivity and Neurophysiology de la Russian Accademy of Sciences (RAS) en Moscú.Este estudio de la Agencia Nacional Rusa de la Investigación sugiere que una dieta abase de alimentos modificados genéticamente puede causar daños a la descendencia.548

Tal estudio fue presentado a un simposio del American Academy of EnvironmentalMedicine sobre las modificaciones genéticas el 10 de octubre de 2005, por laNational Association for Genetic Security (NAGS). El estudio fue realizado por ungrupo de investigadores conducido por la doctora Irina Ermakova, bióloga delInstitute of Higher Nervous Activity and Neurophysiology de la Russian Accademy ofSciences (RAS). Durante el experimento, la doctora rusa añadió soja OMG a lacomida de los ratones hembra dos semanas antes de la concepción y durante lalactancia. No se añadía nada a la comida de los ratones hembra del grupo de control.A los tres grupos de ratones se subministraba una dieta diferente: un grupo de controlno recibía soja, el segundo recibía soja OMG y el tercer grupo recibía sojaconvencional (o sea, NO OMG). Los científicos contaron los nacimientos y lasmuertes de los animales sometidos a este experimento. Tres semanas después delnacimiento de los pequeños, se contaron los muertos. Se llegó a descubrir la siguientecosa: la soja convencional y la soja OMG no influenciaban el número de ratonesmuertos nacidos por cada madre. Sin embargo, el número de los muertos tras 3semanas fue muy diferente. Los resultados indicaron que la soja convencional (o sea,NO OMG) no tiene algún efecto sobre el porcentaje de los ratones muertos, mientrasque la soja OMG aumenta el porcentaje de los ratones muertos, en relación de unocada 8 nacimientos. Además, el 30% de los nacidos en el grupo de ratonesalimentados con soja OMG, pesaba 20 gramos menos de lo normal. Estos hechos hande considerarse muy graves, ya que la morfología y la estructura de los ratones sonmuy parecidas a las del hombre. (Artículo original en: GM Food Dangers DirectlyAffect Biological Descendants and Future Generations, publicado por Robin Good,MasterNeMedia.org el día 1 de noviembre de 2005.Se vea, además: Ermakova IV, “Genetically modified soy leads to the decrease ofweight and high mortality of rat pups of the first generation”, preliminare studies.EcosInforms 2006, 1, 4-9 (en Ruso). Un documento completo se publicará a breve:Ermakova IV, Genetics and ecology, en: Actual problems of science, Moscú, 2005,págs. 53-59 (en Ruso). http://eco-irina-ermakova.narod.ru/eng/index.htm549

TERCER PUNTO DE LA AMENAZA OMGFracaso de la dieta anti-cáncerComo ya ha sido demostrado por Gerson (www.gerson.org) y por otros médicos,muchísimas sustancias contenidas sólo en la fruta y en la verdura cruda y biológicapueden inducir una CASCADA INMUNITARIA contra el cáncer, una detoxificacióny el singular fenómeno de la apoptosis (suicidio) de las células enfermas, sin tenerque recurrir a investigaciones complicadas y muy caras.De este modo, según un experimento que subministraba a 153 pacientes afectos porla peor forma de cáncer conocida (Melanoma) la dieta anti cáncer del Doctor Gersondurante un periodo de cinco años se llegaba a porcentajes de cura del70-90% (si el tumor todavía se localizaba)y del 40-70% (si el tumor ya había producido metástasis)siempre que los pacientes no se hubieran sometido antes a Quimioterapia.Hildebrand, G.L.: Five year survival rates of melanoma patients trated by diet therapy after the manner of Gerson: aretrspective review, in Alternative Therapies, vol. 1 [4], September 1995, págs. 29-37. www.gersonresearch.org/docs/HildenbrandGLG-1996-1/index.htmlLa clave de la eficacia curativa de estas singulares dietas vegetarianas está en que noasimilan nunca alimentos que contienen todos los potenciales de crecimiento celular,en particular: EVITAN la asimilación contemporánea (1-3 horas) de TODOS los9 aminoácidos esenciales (Valina, Isoleucina, Leucina, Lisina, Metionina,Histidina, Triptófano, Fenilalanina, Treonina)Porque sólo mediante ellos las células del cáncer pueden construir PROTEÍNAS, osea otras células enfermas.Además, hay que evitar la asimilación de: ácidos nucleicos, vitamina B12, ácidofólico (porque determinan la duplicación del ADN de la célula del cáncer)hace tiempo, ...antes de la era de los alimentos OMG, esta norma se ponía en prácticamuy fácilmente: los alimentos que contenían todas esas sustancias eran sólo de origenanimal (carne, pescado, huevos, levadura, leche, queso, mantequilla...) que Gerson yotros autores (así como las medicinas china e india) prohibían consumir por lo menosdurante 1 año.De este modo, la alimentación más adecuada era la sólo la vegetariana, o sea a basesólo de fruta y de verdura, incluidos los cereales y las legumbres.550

Los cereales y las legumbres son ricos en AMINOÁCIDOS ESENCIALES,y por este motivo puede sorprender que muchas otras escuelas occidentales, indias ychinas de medicina natural los utilizaran en la terapia contra el Cáncer.El éxito de estas terapias así lejanas en lo que concierne a TEORÍA, pero tansimilares en su eficacia práctica contra el CÁNCER se podría explicar basándose enla moderna BIOQUÍMICA con el hecho de que NINGÚN CEREAL y NINGUNALEGUMBRE contenía solo TODOS los 9 Aminoácidos EsencialesSin embargo, si unimos estos alimentos en la misma comida, determinan laasimilación de los 9 Aminoácidos Esenciales.Y el cuerpo humano puede de tal modo sintetizar PROTEÍNAS y construir células(...cancerígenas).Comparando las viejas terapias, entonces, se denota la PROHIBICIÓN ABSOLITAde comer CEREALES Y LEGUMBRES juntas, o sea Pasta (o Polenta o Pan [aunquesea ázimo] o arroz) con legumbres, porque, con la moderna BIOQUÍMICA, hoy endía sabemos que se integran los nueve Aminoácidos Esenciales: (los cerealescontienen sólo 8, falta la Lisina, presente en las legumbres) ; (las legumbrescontienen sólo 8, falta la Metionina, presente en los cereales)de este modo el efecto nutricional es similar al de la carne.Sin embargo, hoy en día a través de la introducción en el comercio de cereales,legumbres y otros vegetales modificados genéticamente (OMG), muchos de estosalimentos contienen TODOS los Aminoácidos Esenciales ( Day P.R.: Genetic modificationof plants: significant issues and hurdles success, Am.J.Clin.Nutr., 63(4), págs: 651S-656S, 1996http://www.mednat.org/alimentazione/DAY.pdf) convirtiendo de tal modo el Cáncer en NO curablesegún lo descrito en este trabajo, por la terapia de Gerson, y en los trabajos demuchos otros autores.551

CUARTO PUNTO DE LA AMENAZA OMGEnfermedades inducidas por virus transgénicosLos virus transgénicos con los que hoy en día se obtienen los OrganismosModificados Genéticamente (O.M.G.) entran en el ADN de la planta y la modificande modo desconocido.Se supone que estos virus quedan latentes, pero nada puede excluir que puedanreactivarse de manera parecida a los ya bien conocidos virus tumorales de ARN(Oncornavirus) o como virus tumorales de ADN (ambos causan leucemias, sarcomas,carcinomas, gliomas...).Estos virus pueden incluso introducir nuevas enfermedades o enfermedades bastanteparecidas a síndromes muy conocidas y cuya dinámica todavía no ha sido del todoentendida (SIDA, Vaca Loca, etc....) y cuya origen es todavía muy vaga (¿causadaspor virus transgénicos?).Para más información sobre los virus usados para obtener OMG aconsejamos el libroin INTERNET “Mille Piante per guarire dal Cancro senza Chemio”(http://www.medicinetradizionali.it/nacci.htm http://www.erbeofficinali.org/dati/nacci/index.php ;http://www.alternativemed.eu/cancro/1000%20piante_cancro.pdf ; http://www.mednat.org/Nacci%20libro.pdf ;http://www.medicinetradizionali.it/nacci.htmEs de conocimiento común que el CaMV (Cauliflower Mosaic Virus – Virus delMosaico de la Coliflor) hoy en día se usa para replicar retrovirus introducidos en lasplantas por las multinacionales OMG para modificar el ADN de las plantas (yconvertirlas en plantas OMG).Este virus está activo en todas las plantas (Angiospermas y Gimnospermas).El uso de este virus por parte de las Multinacionales OMG para modificargenéticamente las plantas se debe a los singulares promotores (“motores” deactivación genética) que contiene.El CaMV tiene dos de estos promotores: el 19S y el 35S.De estos dos, el 35S es el promotor más usado por las Multinacionales.El promotor 35S es una secuencia de ADN con más o menos 400 bases (unidades desecuencia génica, caracterizada por 4 distintas moléculas: Adenina, Citosina, Guaninao Timina)El promotor CaMV es el preferido entre todos los promotores utilizados por lasMultinacionales OMG para modificar las plantas, porque las distintas condiciones de552

los tipos de tejido celular vegetal no lo influencian, de modo que es eficazindistintamente.Desafortunadamente, el CaMV puede penetrar y replicarse incluso en las células delos animales, como en las de los mamíferos y en las de los humanos, como sedemuestra en la obra de Vlasak, del 2003 (Vlasak J.: Comparison of hCMV immediate early andCaMV 35S promoters in both plant and human cells, Journal of Biotechnology No. 103, págs: 197-202, 2003http://www.dirittolibertadicura.org/images/OGM/clasak.pdf http://www.mednat.org/alimentazione/vlasak.pdfEstos para-retrovirus artificiales, creados y usados por las Multinacionales paramodificar el ADN de las plantas, se parecen a los retrovirus ya presentes en lanaturaleza como: el retrovirus VIH del SIDA, el de la LEUCEMIA HUMANA, o elde la Hepatitis B humana.(Bonneville: Retrovirus, Viroids and RNA recombination, RNA Genetics, Vol. 11, págs: 23-42, 1988).De hecho, se sabe por la literatura científica, que el CaMV está estrechamente ligadoal virus de la Hepatitis B humana y al del SIDA.(Doolitte: Quart.Rev.Biol. 64, 2, 1989); (Xiong and Eickbush, Origin and evolution of retroelements basedupon their riverse transcriptase sequences EMBO Journal 9, pág. 3353, 1990http://www.mednat.org/alimentazione/EMBO%20JOURNAL%201990.pdf)El riesgo usando el CaMV en plantas usadas para la alimentación animal y/o humanase caracteriza por la RECOMBINACIÓN GENÉTICA de los cromosomas (ADN) delas plantas, pero esto determina la posible recombinación del mismo promotor 35Sincluso con el ADN del animal o de la persona que se ha comido la fruta, la verdura,la pasta o la soja OMG y que, de esta forma, contienen esos para-retrovirusartificiales.Los virus pueden incorporar, en la RECOMBINACIÓN GENÉTICA, genes celularespresentes en la planta o en el animal que en precedencia se nutrieron de esa plantaOMG, para pasar al hombre (nutriéndose del animal), con efectos genéticos del tododesconocidos.Una de las más probables consecuencias es la manifestación de cánceres y deleucemias.Otra consecuencia es la modificación genética en la descendencia.En ambos casos, el sistema del ADN “saltaría” de manera similar mediante laexposición a las radiaciones ionizantes, con la diferencia que se presentaría incluso laamenaza de la manifestación de nuevas enfermedades infectivas.NUEVAS ENFERMEDADES INFECTIVAS: se ha demostrado la manera en quelos genes del CaMV incorporados en los cromosomas de plantas (Canola) se553

ecombinan con virus infectivos para producir enfermedades virales mucho másvirulentas.Gal, en una obra de 1992, ilustra ese modelo experimental sobre la cuestión de laseguridad de las plantas transgénicas que contienen genes virales transgénicos comoel CaMV. Gal S.: Agroinfection of transgenic plants leads to viable Cauliflower Mosaic Virus byintermolecular recombination, Virology, No. 187, págs: 525-533, 1992http://www.dirittolibertadicura.org/images/OGM/gal.pdf http://www.mednat.org/alimentazione/Gal.pdfSobre la recombinación entre CaMV y otros virus que implican el promotor se veatambién el trabajo de 1990 de Vaden Ray Vaden: Recombination sites in Cauliflower MosaicVirus DNAs; implications for Mechanisms of recombination, Virology, No.177, págs: 717-726, 1990http://www.dirittolibertadicura.org/images/OGM/ray%20vaden%20.pdfOtros estudios científicos han demostrado que estos retrovirus pueden intercambiarentre ellos cadenas de ADN con otro ADN y ARN con otro ARN, creando nuevasinfecciones virales. (Mol.Plant-Microbe Interactions 5, 48, 1992).Experimentos similares sugieren como las alteraciones de las plantas puedanprovocar enfermedades mortales como se puede leer en el trabajo de Greene de 1994.Greene A.e.: Recombination between viral RNA and transgenic plant transcripts, Science, Vol. 263, 11march 1994http://www.dirittolibertadicura.org/images/OGM/greene.pdfhttp://www.mednat.org/alimentazione/Greene.pdfMuy peligrosas cadenas de ADN viral producidas por normales virus a ARN sepropagan muy rápidamente en el ambiente vegetal (plantas OMG) usando elpromotor 35S del CaMV para conducir la producción de virus de ARN que de otramanera no se podrían propagar en el ADN de las plantas. Pero desde aquí puedenpasarse al ADN de animales (incluso el hombre) o en el de bacterias y/o virus.Boyer J.C.: Infectious transcripts and cDNA clones of RNA Viruses, Virology, No. 198, págs: 415-426, 1994http://www.dirittolibertadicura.org/images/OGM/boyer.pdf ; http://www.mednat.org/alimentazione/Boyer.pdfSteinbrecher R.A.: The CaMV 35S Promoter fragmentation hotspot confirmed, and it is active in animals,Microbial Ecology in Health and Disease 2000, 12, págs: 189Mae Wan Ho: The CAMV 35S Promoter fragmentation hotspot confirmed, and it is active in animals,Microbial Ecology in Health and Disease 2000, 12, págs: 189http://www.mednat.org/alimentazione/MaeWanHo1.pdfMae Wan Ho: Cauliflower Mosaic Viral Promoter – a recipe for disaster, Microbial Ecology in Health and Disease1999, 11, pp: 194-197http://www.mednat.org/alimentazione/MaeWanHo2.pdfEn conclusión, el promotor CaMV se recombina con los virus infectivos paraproducir nuevas enfermedades virulentas.554

El virus CaMV y sus promotores 19S y 35S pueden incorporar genes del ADN de laplanta-huésped, del animal-huésped o de la bacteria huésped, o de otro virus (con talque sea de ADN), creando nuevas enfermedades virulentas.En este último caso (virus de ADN), el CaMV se puede recombinar con los virus deADN de los insectos y propagarse así en las células de los insectos.(Zuidema D.: J.Gen.Vir. 71, págs.312, 1990). http://www.mednat.org/alimentazione/zuidema.pdfDe este modo, es plausible que gran parte de la población humana, consumiendotomates modificados genéticamente con el CaMV (recombinado por ejemplo con elvirus del Hepatitis humana B), pueda crear un SUPER-VIRUS capaz de propagarseasí en las plantas de uso alimenticio, en los insectos (como, por ejemplo, losmosquitos) y de este modo llegar al hombre.Allison R.F.: Recombiantion in plants expressing viral transgenes, Seminars in Virology, Vol. 7, págs: 417-422, 1996http://www.dirittolibertadicura.org/images/OGM/allison.pdf ; http://www.mednat.org/alimentazione/Allison.pdfWintermantel W. M.: Isolation of recombinant viruses between Culiflower Mosaic Virus and a viral gene intransgenic plants under conditions of moderate selection pressure, Virology, No. 223, págs: 156-164, 1996http://www.dirittolibertadicura.org/images/OGM/wintermantel.pdfhttp://www.mednat.org/alimentazione/Wintermantel.pdfLatham J.: GM Gene Flow (B): Horizontal gene transfer of viral inserts from GM plants to viruses,Technical paper, February 2004 http://www.dirittolibertadicura.org/images/OGM/latham.pdfJ.T. Dessens : Cauliflower mosaic virus 35S promoter-controlled DNA copies of cowpea mosaic virus RNAsare infectious on plants, Journal of General Virology, No.74, págs: 889-892, 1993http://www.mednat.org/alimentazione/dessens.pdfExisten retrovirus naturales que en los animales o en el hombre provocan leucemia,linfomas, sarcomas o el cáncer de mama (véase, para más información, el alegado 5del libro on-line “Mille Piante per guarire dal Cancro senza Chemio-ottobre 2008”).(http://www.medicinetradizionali.it/nacci.htm http://www.erbeofficinali.org/dati/nacci/index.php ;http://www.alternativemed.eu/cancro/1000%20piante_cancro.pdf ; http://www.mednat.org/Nacci%20libro.pdf ;http://www.medicinetradizionali.it/nacci.htm ).Tales retrovirus son muy peligrosos y una recombinación causal con el promotor35S del Cauliflower Mosaic Virus tiene que considerarse muy probable, si seintroducen las plantas modificadas genéticamente en la alimentación animal y/ohumana.Búsqueda de retrovirus OMG en los tumores humanosSe considera necesaria la búsqueda, en pacientes enfermos de tumor, de eventualeshibridismos entre el ARN polisomial (de sospecha origen viral OMG, deOncornavirus modificado para producir plantas OMG de uso alimenticio) obtenido555

por tumores humanos de pacientes que se habían alimentado de comida OMG y elADN sintetizado en laboratorio por transcripción inversa por los mismosOncornavirus modificados para producir OMG.Nota: todo esto requiere el acceso a informaciones reservadas, a lo mejor patentadas,por lo que concierne a modelos de retrovirus empleados por las multinacionalesOMG y por lo que concierne a las modificaciones aportadas a los retrovirus por partede las mismas empresas antes de la introducción en el comercio de las mismasplantas OMG.Resulta mucho más difícil encontrar virus tumorígenos de ADN empleados por lasmultinacionales OMG para modificar el ADN de las plantas de uso alimenticio, yaque estos virus (Pox-virus, Herpes-virus, Adeno-virus), a diferencia de losOncornavirus, no se pueden encontrar en el suero o en la orina del paciente.De todas formas, se ha demostrado como en el citoplasma de células tumorales demamífero infectadas y modificadas por estos virus de ADN queda una pequeñafracción, altamente específica, de ARN mensajero, que no se encuentra ni en célulasnormales, ni en células tumorales infectadas por otros tipos de virus oncogénicos deADN.Se trata entonces de averiguar la eventual hibridación entre este ARN mensajero (desospecha origen viral OMG, o sea de virus de ADN modificado para producir plantasOMG de uso alimenticio) obtenido del citoplasma de células tumorales de pacientesque se habían alimentado de comida OMG, y ADN sintetizado en laboratorio por losmismos virus de ADN modificados para producir OMG.Aquí también se requiere el acceso a informaciones reservadas, a veces patentadas,por lo que concierne a modelos de virus a ADN empleados por las multinacionalesOMG y a las modificaciones aportadas a los virus por las mismas empresas antes delacceso al comercio de las mismas plantas OMG.Una hibridación positiva, revelada por la formación de ADN híbrido radioactivo(P32) indica la presencia de secuencias de ADN viral en las células transformadas(Green, Perspect Biol. Med., 1978).La cobertura de informacionesLas Multinacionales están invadiendo el mundo con Omg “secretos”, o sea cuyamodificación se desconoce ya que está cubierta por secreto industrial.556

Esto significa que, no teniendo a disposición la información de base, no podemos nipreparar métodos de análisis y control.Todo esto es muy grave porque tales se producen en Estados Unidos y en otros paísesdonde no se separan las hileras OMG free y las exportaciones pueden resultarcontaminadas.¿Qué hacer?Por primera cosa, pedir informaciones al Istituto Superiore di Sanitá, al IstitutoZooprofilattico de Roma, al Ministero dell'Agricoltura y a la Comisión Europea paraque activen una interrogación y una investigación Parlamentar.Sin embargo, la Comisión Europea solicita la autorización para el comercio de talesOMG en Europa con objeto alimenticio, amenazando el cierre completo de lasimportaciones provenientes de Estados Unidos...o sea, ya que los Omg nos los mandan a escondidas, si los aprobamos, podremoscontrolarlos...Sin embargo, es muy probable que una acción política fuerte, en virtud del principiode precaución del tratado de Maastrischt, pueda evitar la pantentabilidad de los Omgy cada forma de “secreto” industrial sobre las manipulaciones genéticas.Incluso porque tales “secretos” podrían interesar no sólo los alimentos importantes,sino también las semillas... abriendo camino a una contaminación irreversible eindiscriminada de la agricultura europea.557

QUINTO PUNTO DE LA AMENAZA OMGIntoxicación por medio de venenos sintetizados a partir de plantas transgénicasIntoxicación crónica de alimentos a causa de sustancias tóxicas contenidas en lasplantas para convertirlas en resistentes a los parásitas como el Bacillus tourigiensis,con un posible incremento de Cánceres, Abortos espontáneos, Mutaciones genéticasen la descendencia, SIDA, enfermedades degenerativas y causadas por sustanciastóxicas, etc....Por ejemplo, se ha demostrado como el Maíz Omg provoca lesiones a la cavidadbucal de ovejas y de rumiantes.Este estudio, de 2003, demostró como la consumición de Omg perjudica la pared dela cavidad bucal y se asocia a las muertes inexplicables de animales de experimentos:ovejas y rumiantes.Duggan et al, Fate of genetically modified maize DNA in the oral cavity and rumen of sheep, British Journalof Nutrition, 89(2): 159-166, 2003 http://www.mednat.org/alimentazione/Duggan_GMO_Mais.pdfSEXTO PUNTO DE LA AMENAZA OMGPeligro de carestías a nivel mundial a causa de la tecnología “TERMINATOR”Pasaje a especies “indígenas” naturales de trigo, arroz, maíz, patatas, legumbres, de laincapacidad por parte de las plantas mismas de reproducirse normalmente a causa dela tecnología “TERMINATOR”, provocada por la polinización cruzada, con lapérdida irreversible incluso por parte de las plantas de uso alimenticio, hoy en díaempleadas en la alimentación humana, porque estas últimas fueron contaminadas porgenes transgénicos provenientes de zonas agrícolas a cultivo transgénico (OMG) detipo “TERMINATOR”.De este punto nace la potencial amenaza de futuras carestías a nivel global, de tipodescontrolado, ya que no habrá cantidad suficiente de trigo, arroz, maíz o delegumbres de tipo “natural” o de todos modos NO-TERMINATOR.SÉPTIMO PUNTO DE LA AMENAZA OMGModificación transgénica de plantas naturalesPasaje a especies “indígenas” naturales de las sustancias tóxicas artificiales, como porejemplo el “Bacillus thuringiensis” o de otro tipo, a través de polinización cruzada,con potencial amenaza incluso para las plantas y las hierbas médicas hoy en díaempleadas en Fito-terapias ya que estas últimas se contaminarán por genestransgénicos provenientes de las zonas agrícolas a cultivo transgénico (omg).558

OCTAVO PUNTO DE LA AMENAZA OMGDesaparición irreversible del patrimonio genético de las plantas naturalesGradual e irreversible desaparición de las diversidades biológicas, o sea de la normalflora natural: fenómeno que ya se está evidenciando en Estados Unidos a causa de lasmodernas prácticas de cultivo que enfatizan el monocultivo transgénico (OMG) conrespecto a los métodos de cultivo diferenciados. Los cultivos transgénicosamenazarán mucho las zonas ricas en biodiversidad (genomas naturales): el flujotransgénico que irá desde las plantas modificadas a las plantas naturales seráinevitable cuando la relación numérica entre áreas cultivadas con plantas artificialessupere la superficie cubierta por las plantas naturales, determinando de este modo lapérdida irreversible de gran parte del patrimonio genético natural de todas las plantasexistentes en el mundo, actualmente equivalentes a más o menos 442.000 especies yaclasificadas, sobre un total que se estima ser de más o menos 600.000-800.000especies.En sustancia:En los últimos años ya un gran número de plantas han ido desapareciendo porque losagricultores han abandonado las plantas naturales, para adoptar variedades de plantasartificiales, o sea genéticamente modificadas, ya que se han uniformado por lo que serefiere al genoma, se han convertido en plantas con un alto rendimiento deproducción (aunque pobres de/en vitaminas), enfermas intrínsecamente (ya quecapaces de sobrevivir en ausencia de pesticidas), convertidas en estériles por razonesde mercado y manipuladas genéticamente para convertirlas en resistentes a losinsectos y a otros animales ya que capaces de producir venenos, o sea sustanciastóxicas que la ganadería comerán, arriesgando la vida del hombre.Hasta en las selvas la variedad genética está hoy en día amenazada por la pérdida delhabita, no solo por prácticas incorrectas de deforestación, sino también por lacontaminación del patrimonio genético que se ha adaptado a situaciones locales porparte de híbridos creados por las grandes empresas de semillas que producen los omg.Los productos transgénicos representan entonces, propiamente por como se conciben,un empuje formidable a la acentuación de las características de unilateralidad de losmonocultivos, o sea de desaparición del patrimonio genético natural que existe desdehace millones de años.En un futuro lejano o prójimo no tendremos más todas las variedades de plantas(alimenticias o no), características de cada particular región nacional o local.La contaminación genética ambiental inducida por parte de híbridos creados por lasgrandes empresas de semillas de los omg, que inevitablemente se cruzarán con lasvariedades presentes en la naturaleza, llevará a una pérdida en el patrimonio genéticonatural (pérdida no recuperable), de todas las singulares características que han559

entrado en el genoma de las plantas en el curso de los largos procesos de adaptación alas diferentes situaciones ambientales.Tal pérdida hoy en día resulta muy grave hasta para los ambientes naturales como lasselvas. Fundamentalmente, la misma base de la bioquímica humana hoy en día estáamenazada en su más íntima esencia (ADN humano) por el uso desconsiderado deestas plantas artificiales, sin alguna posibilidad de recuperar un patrimonio genéticode más de 44.000 especies de plantas clasificadas (sobre un total de 600.000-800.000estimadas), cuya buena parte desaparecerá en pocos centenares de años, minadas a labase de daños genéticos introducidos por el hombre.Multinacionales agroalimentarias (Biotech, OMG)Desde hace ya unos años están naciendo multinacionales que se definen“Multinacionales de ciencias de la vida” activas en el mercado farmacéutico, en loque concierne al negocio agrícola (semillas y pesticidas) y veterinario.Se trata de sectores diferentes, aunque ligados por el uso de biotecnologías (OMG)para realizar sus productos.Estas multinacionales están utilizando estrategias económicas bastante inescrupulosasy agresivas: desde principios de los noventa operan para comprar empresas incluso degrandes dimensiones.Asgrow, Agracetus, De Calb y Cargil fueron adquiridas en pocos años por una deellas, Monsanto, con la inversión de unos actuales 10 millones de euros.Dupont, otro gran grupo, adquirió Pioneer con una inversión de 8 millones de eurosactuales.Estas inversiones parecen tener una lógica anti-económica: terminan adquiriendo lasempresas por un precio mucho más alto de su valor real, como si intentaran eliminarun potencial competidor y no obtener un resultado económico a corto plazo.Al lado de las adquisiciones tenemos las fusiones: Ciba Geigy y Sandoz creanNovartis (facturado de 20 mil millones de Euros actuales en 1997-1998).De la fusión entre la francesa Rhone Poulenc y la alemana Hoechst, nace Aventis.Siempre en este contexto nace, en octubre de 2000, el primer grupo mundial deagroquímica, Syngenta, - resultado de la fusión entre la suiza Novartis (Empresa560

conocida por la producción de fármacos para la Quimioterapia) y la anglo-suecaAstra-Zeneca (conocida también por la producción de fármacos para laQuimioterapia), que realizará un negocio de aproximadamente ocho mil millones deeuros. Monsanto, tras la fusión con Pharmacia & Upjohn, una gran empresafarmacéutica (también conocida por la producción de fármacos para laQuimioterapia), se ocupa ya sólo de agricultura, con un negocio que en el año 2000alcanzó los cinco mil millones y medio de dolares.La situación actual es la siguiente: muy pocas multinacionales (Syngenta, Monsanto,Novartis, Dupont, Aventis) detienen el 25-30% de la producción de semillas (peromás del 90% del mercado de las semillas transgénicas) y detrás de estos grandesgrupos se denota una tal pulverización que nos induce a pensar que este curso enfuturo podrá sólo reforzarse, ya que las medias empresas no pueden contrastar lacompetencia de grandes grupos económicos. El objetivo parece claro: reconvertir elsector tradicional de las semillas en biotecnológico (o sea, OMG). Pero el datoimpresionante es que volvemos a encontrar los mismos nombres en el sector de lospesticidas, donde las mismas empresas detienen el 55% del mercado y sobre todo enel sector farmacéutico, donde las mismas multinacionales tienen una posicióndominante.561

Multinacionales químico-farmacéuticas (Big-Farma)La historia de las multinacionales químico-farmacéuticas es increíble por sudesarrollo vertiginoso, hoy en día saldado de manera extremadamente peligrosa conel mundo agro-alimentar.La industria químico-farmacéutica nació en Europa en la segunda mitad del sigloXIX: en muchos casos se trataba de industrias de colorantes que, separados de laquímica de base, se dirigían hacia los nuevos y más prometedores sectores de laQuímica especializada, que ocubaba sectores clave de la economía.En los años antes de la Segunda Guerra Mundial, se formó un cártel internacional defármacos, con sede en Alemania, que dominaba las industrias químicas yfarmacéuticas de todo el mundo. El cártel había difundido sus actividades en 93países y en cada uno representaba una potente fuerza económica y política. Seconocía con el nombre de IG Farben.IG Farben se iba a convertir en el pilar de la producción química de Hitler durante losaños de la guerra, abasteciendo de productos que comprendían potentes explosivos,gas tóxicos y el ignominioso Zuklon-B, la sustancia mortal usada por los nazis en loscampos de exterminio.Si embargo, antes de la guerra, en 1928, el industrial monopolista americano John D.Rockerfeller estableció una concentración industrial entre su imperio internacionalcon sede en América y la IG Farben, dando origen al más grande y más potente cártelfarmacéutico que el mundo hubiera conocido.El Juzgado militar de Núremberg en 1946/47 estableció que la Segunda GuerraMundial no hubiera sido posible sin este cártel petrolquímico llamado IG Farben.Tras la sentencia pronunciada por el juzgado, IG Farben se dividión en Bayer, BASFy Hoechst y algunos de sus dirigentes fueron condenados por haber empezado unaguerra contraria al derecho internacional, por genocidio, explotación y saqueo depropiedades públicas y privadas en países extranjeros y otros crímenes contra lahumanidad.La historia de los antecedentes empresariales detrás de la segunda guerra mundialestá documentada en el libro de Joseph Borkin “The Crime and Punishmenti of IGFarben” (El Crimen y Castigo de IG Farben).Tras la guerra, Alemania con sus tres gigantes Bayer, Hoechst, BASF tuvo lo mismoun papel importante, junto a Suiza que, en Basilea, vio nacer y desarrollarse a Ciba,Sanzoz y Roche: tres empresas que se afirmarán en el mundo.562

Sin embargo, fue en los noventa que empezaron las grandes fusiones: en ReinoUnido, en 1989 dos grandes empresas farmacéuticas se fundieron en Smith Kline-Beecham: más tarde se fundirán también con American Home (aproximadamente 25mil millones de euros de facturado anual).En 1993 la sueca Pharmacia compró la italiana Farmitalia – Carlo Erba, y en 1995con la americana Upjon y más tarde con Monsanto, antes de que Pfizer (que ya habíacomprado la americana Parke Davis) la comprara.En 1995 se lidera la fusión Glaxo-Wellcome (aproximadamente 14 mil millones deeuros de facturado anual).En 1998 Smith Kline – Beecham (aproximadamente 62 mil millones de Euros defacturado anual) se funde con Glaxo-Wellcome, con un capital resultante de más de90 mil millones de euros de facturado anual.Mientras tanto, la inglesa Imperial Chemical Industries se había fundido con la suecaAstra, creando a Astra-Zeneca.Las fusiones han seguido liderándose entre las mismas empresas farmacéuticaspresentes en el mismo tipo de mercado: Sandoz y Ciba Geigy (Novartis, 1996), Astra-Zeneca (1998).Estas potencias no nacen de la exigencia de los pacientes, sino de la exigencia decrear un monopolio y provechos siempre mayores.Últimos datos:Junio de 2002: compra de Aventis por parte de Bayer; este acuerdo consiente a Bayerde entrar en el campo de las semillas modificadas genéticamente. La fusión lleva a lacreación de Bayer CropScience, que llega a tener tres grupos comerciales principales:Crop Protection, Bio Science y Environmental Science.Junio de 2005: compra de Sementis por parte de Monsanto.La uniónEs posible por tanto afirmar que los dos fundamentos de la economía y de la vida decada individuo, o sea la agricultura y la farmacéutica, están controladas en unasituación de substancial oligopolio por parte de muy pocos grupos multinacionales.563

CONCLUSIÓNEstamos frente a una encrucijada entre la aceptación de las modificacionesbio-químicas de las plantas, con daños inmensos a la salud de lahumanidad, o la postura de las Instituciones democráticas de nuestrasociedad contra las Multinacionales OMG y químico-farmacéuticas que,con su unión, están detrás de la invasión irresponsable del mundo a travésde OMG.La solución es simple, pero tenemos sólo 4 meses para parar los OMG dela que justamente el Profesor Altieri define un evento IRREVERSIBLE:1) Prohibición absoluta de permitir el cultivo de plantas OMG2) Prohibición absoluta de experimentar en los campos (peligro detransferencia génica horizontal)3) Revaluación de la Agricultura Biológica (que incluso tiene mayorrendición)4) Defensa de la bio-diversidad, en particular restablecimiento de lalibertad de intercambio de las semillas campesinas.Si todo esto no pasará, habrá que pensar en un SEGUNDO NÚRNBERG...Gracias.564

ALLEGATED 19SANA Kongress – 13. September 2008 in BolognaGefördert von AAM Terra NuovaWissenschaftliche Koordination: Studio AgernovaGiuseppe Nacci und Giuseppe Altieri“Die GVO-Bedrohung (Genetisch Veränderte Organismen) für begleitendeErnährungsmodelle zur Immun- und Entgiftungstherapie ”565

Krebs ist eine degenerative Krankheit, deren Ursprung im Vitaminmangel und in einer durchchemische Substanzen vergifteten Nahrung liegt.Man schätzt, dass in den natürlichen Pflanzen der allgemeinen menschlichen Ernährung ca. über13.000 bis 15.000 Vitamine und Provitamin-Substanzen enthalten sind.Die Einführung von genetisch veränderten Organismen (GVO) in der modernen Landwirtschaftstellt eine ungerechtfertigte und äußerst gefährliche Veränderung dessen dar, was die Evolution inhunderten Millionen Jahren in den Pflanzen hervorgebracht hat:Pflanzen, auf denen die nachfolgende biochemische Evolution der komplexen Organismen derhöheren Lebewesen basiert, die mit dem Auftreten der Säugetiere in den letzten 65 MillionenJahren und schließlich mit dem Erscheinen des Menschen ihren Höhepunkt findet.Das sensible biochemische Gleichgewicht der Spezies Mensch hängt daher ab von der Integrität derPflanzenarten, so wie sie die Evolution bis zu uns herauf gesteuert hat, denn die Gesundheit vonjedem von uns basiert auf der Biochemie der menschlichen Zellen, und diese hängt in ihrer eigenengenomischen Komplexität (DNA) vom Einsatz von tausenden Vitaminen und in der Naturpräsenten phytochemischen Komplexen ab.Auch die Pflanze selbst ist ein komplexer Organismus, das Ergebnis einerhunderte Millionen Jahre dauernden biologischen Evolution.Jede durch den Menschen hervorgerufene genetische Veränderung (durchStrahlungen wie in Tschernobil oder mit Retroviren, wie sie momentan mit denGVO passieren) provoziert auf jeden Fall Schäden, irreparable Schäden, die oftnicht erkannt werden können, weil überhaupt nur wenige Dutzend Vitamineund andere Provitamin – Substanzen mit Sicherheit nachgewiesen sind.Umgekehrt gibt es zig-tausend Vitamine und andere in den Pflanzen enthalteneSubstanzen, die für das korrekte Funktionieren der komplexen menschlichenBiochemie und des menschlichen Genoms (DNA) verantwortlich sind.Um den Vorteil einer (vorgeblichen) höheren landwirtschaftlichen Produktion zuerzielen, bedient man sich heute der Methode, das genetische Erbgut der natürlichenPflanzen zu verändern, wobei folgende Ziele verfolgt werden:1) Strukturveränderung der Pflanzen,2) Sterilisation der Pflanzen (um die Landwirte zu zwingen, sich jedes Jahr neuesSaatgut zu kaufen),3) Patentierung der vorgenommenen Veränderungen,4) weltweiter Wiederverkauf des so erhaltenen Produkts.566

In Wirklichkeit ist nie bewiesen worden, dass die GVO Kulturen größereProduktmengen hervorbringen, ganz im Gegenteil, wie aus den unabhängigenwissenschaftlichen Arbeiten der ISIS hervorgeht.Überdies wird behauptet, dass es eine wesentliche Äquivalenz gibt zwischen:1) dem genetisch veränderten Produkt (GVO)2) und dem Produkt, das man durch Selektion der genetischen Merkmale erhält (dasheißt durch natürliche Kreuzung von Pflanzen, wie der Mensch dies eben seitTausenden Jahren durchführt).Wir hingegen behaupten, dass die Aussage „wesentliche Äquivalenz“ absolutunhaltbar ist, denn:1) Die natürliche Kreuzung von Pflanzen erfolgt mit natürlichen Samenderselben Art, während die Genmanipulation (GVO) über die Grenzen derPflanzenarten hinaus erfolgt, und zwar mittels Einführung von Genen andererPflanzenarten oder sogar von Bakterien, Viren oder Tieren.2) Der Großteil der in der Gentechnik verwendeten Gene stammt in der Tat vonlebenden Arten, die nie ein Teil der menschlichen Nahrung gewesen sind undstammen noch dazu sogar von DNAs, die nicht zu Pflanzen, sondern zuTieren, Bakterien oder Viren und /oder gentechnisch veränderten Retrovirengehören.Auf diese Weise können wir ACHT unmittelbare Bedrohungen unterscheiden:ERSTENS: Verlust der Provitamin- und Vitaminkomplexe in den PflanzenZWEITENS: Genmutationen der Pflanzen und daraus resultierende Veränderungder menschlichen BiochemieDRITTENS: Scheitern der Krebs-DiätVIERTENS: Krankheiten, die von transgenen Viren ausgelöst werden567

FÜNFTENS : Intoxikation durch Gifte, die von transgenen Pflanzen synthetisiertwerdenSECHSTENS: Gefahr von weltweitem Mangel an natürlichen Pflanzen aufgrund der“TERMINATOR” TechnologieSIEBTENS: transgene Veränderungen von natürlichen PflanzenACHTENS: unwiederbringlicher Erbgutverlust der natürlichen Pflanzen568

PUNKT EINS DER GVO- BEDROHUNG:Verlust der Provitamin- und Vitaminkomplexe in den PflanzenDas vorsätzliche Deaktivieren der in den Pflanzen enthaltenen natürlichenSubstanzen, mit dem Zweck, frisches Obst und Gemüse für einen zeitlich undräumlich langen Transport haltbar zu machen, ist gravierend. In Wirklichkeit wird dieOxidierung dieser nun vitaminarmen Nahrungsmittel durch das Fehlen von ebenvielen dieser Vitamine vermieden.Diese Vitamine aber gelangen in komplexen enzymatischen Mechanismen in dieDNA der Säugetiere und führen dabei in diesen Säugetierzellen im Falle vonInfektionen, vor allem aber bei KREBS- oder LEUKÄMIE-Befall zum Phänomen derAPOPTOSE (Zell-Selbstmord).Dieses Phänomen absichtlicher Vitaminverarmung aus puren kommerziellenZwecken ist ein äußerst gravierender, vorsätzlicher Schadensakt, der dem Ökosystemmittels GVO zugefügt wird.Tausende in Frischpflanzen enthaltene Vitamine sind in der Lage,Immunabwehrreaktionen gegen Keime, Viren oder Tumorzellen auszulösen odersogar Apoptose-Phänomene (Zelltod oder programmierter Tod) in den Tumorzellenselbst hervorzurufen.Die Vitaminmengen, die notwendig sind, im Labor die Apoptose einer bestimmtenAnzahl von Tumorzellen auszulösen, ohne in den gesunden Zellen irgendwelcheSchäden zu provozieren, sind wirklich minimal.In vielen Beiträgen - die meisten im PDF Format verfügbar – der offiziellenmedizinisch wissenschaftlichen Literatur sind die Vitaminmengen angegeben, diein der Lage sind, auf der spezifischen neoplastischen Zelllinie eine APOPTOSEauszulösen; http://www.erbeofficinali/dati/nacci/allpdf.phpDie Mengenangabe wird ausgedrückt in:Mikromol (d.h. Mikromol /l, d.h. Nanomol/ ml, d.h. Pico-Mol/Mikro-Liter).569

PUNKT ZWEI DER GVO-BEDROHUNG:Genmutationen der Pflanzen und daraus resultierende Veränderung dermenschlichen BiochemieDurch die Einführung von Fremdgenen (z.B. von Tieren, Bakterien, Viren,Retroviren) in die Pflanzen-DNA wird in dieser eine Veränderung der normalenGenomsequenz hervorgerufen, es treten neue Proteine auf, und/oder andere Proteineaus der Genomsequenz gehen verloren.Wir erhalten also neue, den natürlichen Vitaminen ähnliche Substanzen, die inWirklichkeit jedoch enzymatische und biochemische Reaktionsvermögen aufweisen,die sich von den natürlichen unterscheiden, und die daher, sobald sie einmal mit derNahrungsaufnahme in den Körper gelangt sind, eine Veränderung der biochemischenAktivität der Zellen auslösen.Das wiederum führt möglicherweise zum Auftreten neuer, durch Genmanipulation (GVO)pflanzlicher Organismen “künstlich” entstandener Krankheiten. Die pflanzlichen Organismenwerden durch neue Vitamin-ähnliche Moleküle genetisch verunreinigt mit induktivenAuswirkungen auf die menschliche DNA und auf ihre komplexe, noch völlig unbekannteBiochemie, die jedoch eben aufgrund ihrer extremen Komplexität und daher Verwundbarkeit sehrwahrscheinlich gravierende Schäden davontragen wird.Der einzige langfristig (24 Monate) angelegte, von einem italienischen Teamdurchgeführte Test ergab, dass GVO Veränderungen bei einigen inneren Organenhervorrufen können. Die Fütterung von Mäusen mit dem berühmten Roundup ReadyMais führte zu einer Struktur- und Funktionsveränderung in den Zellen von Leber,Pankreas und Hoden.(Malatesta M.,.: Fine structural analyses of pancreatic acinar cell nuclei from mice fed on GMsoybean. Eur. J. Histochem., 47:385-388, 2003)http://www.mednat.org/alimentazione/Malatesta.pdf )Eine zweite Untersuchung, die hier aufgezeigt werden soll, stammt von Pusztai: Erentdeckte, dass Mäuse, die mit transgenen Kartoffeln gefüttert wurden, Zeichen vonOrganschäden, Verdickung des Dünndarmes und geringe zerebrale Entwicklungaufwiesen. Die Kartoffeln waren genetisch verändert worden, um durch denLektingehalt resistenter gegen Pestizide zu werden.(Pusztai : Effect of diets containing genetically modified potatoes expressing Galanthus nivalislectin on rat small intestine, The Lancet Vol. 354, October 16, 1999)http://www.mednat.org/alimentazione/Pusztai.pdf )570

Als dritte soll die Prescott-Studie über GVO-Erbsen genannt werden.(Prescott: Transgenic expression of bean-amylase inhibitor in peas results in altered structure andimmunogenicity, J. Agric. Food Chem., 53, (23), pp.: 9023-9030, 2005)http://www.mednat.org/alimentazione/Prescott.pdfEine weitere Untersuchung wurde in Russland von Dr. Irina Ermakova am Institute ofHigher Nervous Activity and Neurophysiology der Russischen Akademie derWissenschaften / Russian Academy of Sciences (RAS) in Moskau durchgeführt.http://eco-irina-ermakova.narod.ru/eng/index.htm .571

PUNKT DREI DER GVO-BEDROHUNG:Scheitern der Krebs-DiätWie schon von Gerson oder auch von anderen Ärzten bewiesen, sind sehr viele, nurin rohem und biologischem Obst und Gemüse enthaltene Substanzen in der Lage,eine IMMUNKASKADE gegen Tumor, Detoxifikation und das besondere Phänomender Apoptose (Zellsuizid) der kranken Zellen auszulösen, ohne dass aufarbeitsintensive und kostspielige Untersuchungen zurückgegriffen werden muss.Auf diese Art und Weise erreichte die Gerson-Krebsdiät, die an 153 Patientenangewendet wurde, die an dem schlimmsten bekannten Krebs (Melanom) erkranktwaren, nach 5 Jahren folgende, in Prozent ausgedrückte Heilungserfolge:70-90% (wenn der Tumor noch lokalisiert war)40-70% (wenn derTumor schon metastasiert war),vorausgesetzt, dass die Patienten vorher keiner Chemotherapie unterzogen wurden.(Hildebrand, G.L.: Five year survival rates of melanoma patients treated by diet therapy after themanner of Gerson: a retrospective review, in Alternative Therapies, vol.1[4], september1995,pp.29-37).(www.gerson-research.org/docs/HildenbrandGLG-1996-1/index.html )Im Gegensatz dazu stehen die Heilungschancen bei Melanomen mit Chemotherapiein 5 Jahren bei 6%, ein Wert, der anderen Quellen zufolge mit Null Prozentangegeben wird.(Morgan G.: The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies,Clinical Oncol., 2004, 16, pp.: 549-560) . www.mednat.org/cancro/MORGAN.PDFEine Überlebenschance von NULL % , die in dieser neuesten australischen Studievon MORGAN, die mit über 270.000 Chemo-Patienten durchgeführt wurde, auchbestätigt wird bei:PankreaskrebsSarkomGebärmutterkrebsProstatakrebsBlasenkrebsNierenkrebsMultiplem Myelom.572

Dieser Prozentsatz erhöht sich dann auf1% bei Magen- und Kolonkrebs,2% ca. bei Brust- und Lungenkrebs,3-5% bei Rektumkrebs,4-5% bei Gehirntumoren,5% bei Speiseröhrenkrebs,9% bei Eierstockkrebs,10% bei NON Hodgkin Lymphom,12% bei Gebärmutterhalskrebs, undsteigt auf ca. 40% bei Seminom des Hodens und beim Hodgkin Lymphom.Der Schlüssel zum Erfolg bzw. die Erklärung für die heilende Wirkung dieserbesonderen vegetarischen Diäten liegt darin:niemals Speisen zu assimilieren, die alle potentiellen Faktoren zum Zellwachstumenthalten, insbesondere sind zu VERMEIDEN: die gleichzeitige Assimilierung (1-3 Stunden) ALLER 9 essentiellen Aminosäuren(Valin, Isoleucin, Leucin, Lysin, Methionin, Istydin, Tryptophan, Phenylalanin,Threonin),denn nur mit ihnen können die Krebszellen PROTEINE d.h. weitere kranke Zellenaufbauen.Zu vermeiden ist auch die Assimilierung von:Nukleinsäuren,Vitamib B12,Folsäure(da sie die DNA-Replikation der Krebszelle auslösen)573

einst, …vor dem GVO - Zeitalter, war diese Regel ganz leicht in die Praxisumzusetzen:Nahrungsmittel, die all dies enthielten, waren einzig allein tierischen Ursprungs,(Fleisch, Fisch, Eier, Hefe, Milch, Käse, Butter…)und sowohl Gerson als auch andere Autoren (einschließlich der chinesischen undindischen Medizin) verboten deren Einnahme für mindestens 1 Jahr.Als erfolgreich erwies sich also die ausschließliche vegetarische Ernährung, d.h. aufBasis von Obst und Gemüse, inklusive Getreide und Hülsenfrüchte.Die letzteren Nahrungsmittel (Getreide und Hülsenfrüchte) sind jedoch reich anESSENTIELLEN AMINOSÄUREN,und es wird verwundern, dass sie trotzdem von vielen anderen Schulen derNaturmedizin im Westen und in der indischen und chinesischen Naturheillehre in derKrebstherapie verwendet wurden.Der Erfolg dieser in der THEORIE so unterschiedlichen, in ihrer praktischenWirkung gegen den Krebs jedoch so ähnlichen Therapien könnte durch die moderneBiochemie erklärt werden, nämlich aufgrund dessen, dass:KEIN GETREIDE und KEINE HÜLSENFRUCHTalleine ALLE 9 essentiellen Aminosäuren enthalten.Werden diese Nahrungsmittel jedoch während einer Mahlzeit gemeinsam zu sichgenommen, verursachen sie die Assimilierung von allen 9 essentiellen Aminosäuren,und der Körper kann auf diese Weise PROTEINE synthetisieren und daher (Krebs-)Zellen aufbauen.Aus dem Vergleich dieser alten Therapieformen geht das ABSOLUTE VERBOThervor, GETREIDE UND HÜLSENFRÜCHTE zusammen zu essen.d.h. Nudelgerichte (oder Polenta, oder Brot [auch ungesäuertes] oder Reis) +Hülsenfrüchte,574

denn dank der modernen BIOCHEMIE wissen wir heute, dass damit eine Integrationder neun Essentiellen Aminosäuren hervorgerufen wird:Sind nur 8 im Getreide enthalten, so ist die fehlende [Lysin] in den Hülsenfrüchtenenthalten,sind nur 8 in den Hülsenfrüchten enthalten, so ist die fehlende [Methionin] imGetreide enthalten.Der Nähreffekt ist dem des Fleisches ähnlich – und im Grunde genommen wurde eineMahlzeit aus Nudeln (Getreide) und Bohnen (Hülsenfrüchte) auch das Fleisch derArmen genanntDurch das Einführen in den Handel von gentechnisch veränderten Hülsenfrüchten,Getreide und anderen Gemüsesorten (GVO) sind jedoch heute in vielen dieserLebensmittel ALLE Essentiellen Aminosäuren vorhanden, wodurch der Krebseffektiv so wie in dieser Arbeit und von anderen beschrieben, in der Gerson-Therapie NICHT mehr geheilt werden kann.(Day P.R.: Genetic modification of plants: significant issues and hurdles success, Am.J.Clin.Nutr.,63(4), pp.: 651S-656S, 1996 http://www.mednat.org/alimentazione/DAY.pdf ).575

PUNKT VIER DER GVO-BEDROHUNG:Krankheiten, die von transgenen Viren ausgelöst werdenDie transgenen Viren, mit denen man heute die Genetisch Veränderten Organismen(GVO) herstellt, gelangen in die DNA der Pflanze, wobei sie diese in einer uns völligunbekannten Art und Weise verändern.Eigentlich sollten diese Viren latent bleiben, doch kann nicht ausgeschlossen werden,dass sie sich in Analogie zu den sehr wohl bekannten RNA - Tumorviren(Onkornaviren) oder den DNA- Tumorviren (beide sind Induktoren für Leukämie,Sarkome, Karzinome, Glyome…) reaktivieren können.Diese Viren können auch Träger neuer Krankheiten oder von Krankheiten sein, diejenen berühmten Syndromen, die in ihrer Dynamik leider noch gering erfasst sind,recht ähnlich sind (AIDS, Rinderwahn, etc…), und deren Ursprung heute noch sehrvage ist (vielleich sind es die transgenen Viren?).Bezüglich der Viren, die zur Herstellung von GVO verwendet werden, steht eineumfangreiche Bibliographie zur Verfügung.Es ist wohl bekannt, dass heute das CaMV (Cauliflower Mosaic Virus) zurReplikation der Retroviren verwendet wird, die von den GVO- Multis in die Pflanzeneingebracht werden, um deren DNA zu verändern (GVO-Pflanzen).Dieses Virus ist sowohl in den so genannten “Angiospermen” als auch in den„Gymnospermen“, d.h. also praktisch in allen Pflanzen enthalten.Die Verwendung dieses besonderen Virus seitens der GVO-Multis zur genetischenModifizierung der Pflanzen ist auf die in ihnen enthaltenen besonderen Promotoren(„Motoren“ zur genetischen Aktivierung) zurückzuführen.Das CaMV hat zwei dieser Promotoren: den 19S und den 35S.Von diesen zwei wird von den GVO-Multis hauptsächlich der 35S verwendet.Der Promotor 35S ist eine DNA Sequenz von ca. 400 Basen (Einheit der genetischenSequenz, die durch 4 verschiedene Moleküle gekennzeichnet ist: Adenin, Cytosin,Guanin oder Tymin)576

Der Promotor CaMV wird deshalb von den GVO-Multis allen anderen verwendetenPromotoren zur Pflanzenmodifikation vorgezogen, weil er im Unterschied zu anderenin die Zellen aller Pflanzen eindringen und hier dann agieren kann.Leider ist er auch imstande, in tierische Zellen, Säugetiere eingeschlossen, und daherauch in menschliche Zellen einzudringen und sich da zu replizieren, wie Vlasek inseiner Studie 2003 deutlich darlegt.(Vlasak J.: Comparison of hCMV immediate early and CaMV 35S promoters in both plant andhuman cells, Journal of Biotechnology No. 103, pp.: 197-202, 2003).http://www.mednat.org/alimentazione/vlasak.pdfDiese künstlichen Para-Retroviren, die auf diese Weise von den GVO-Multis erzeugtund zur Modifizierung der Pflanzen-DNA verwendet werden, sind den schon in derNatur vorkommenden Retroviren wie :dem Retrovirus HIV von AIDS,dem Retrovirus der MENSCHLICHEN LEUKÄMIE,oder jenem der menschlichen Hepatitis Bsehr ähnlich.(Bonneville : Retrovirus, Viroids and RNA recombination, RNA Genetics, Vol. 11, pp: 23-42,1988).http://www.mednat.org/alimentazione/boneville.pdfAus der wissenschaftlichen Literatur weiß man ja, dass das CaMV mit demmenschlichen Hepatits B Virus und dem AISD Virus eng korreliert.(Doolitte: Quart.Rev.Biol. 64, 2, 1989) ; (Xiong and Eickbush, EMBO Journal 9, pp. 3353, 1990)http://www.mednat.org/alimentazione/EMBO%20JOURNAL%201990.pdf )Das enorme Risiko bei der Verwendung von CaMV in Nutzpflanzen als Tierfutterund/oder für den Menschen besteht in der GENETISCHEN REKOMBINATION derChromosomen (DNA) der Pflanzen, dies verursacht jedoch die möglicheRekombination des Promotors 35S selbst auch mit der DNA des Tieres oder derPerson, die die GVO- Frucht, das GVO-Gemüse, die GVO-Nudeln oder die GVO-Soja, die eben solche künstliche Para-Retroviren enthalten, eingenommen hat.Die Viren können in der GENETISCHEN REKOMBINATION auch in der Pflanzeoder in dem Tier, das vorher mit einer GVO Pflanze ernährt wurde, enthaltenezelluläre Gene aufnehmen, um dann in den Menschen zu gelangen (der sich von demTier ernährt hat), mit genetischen Auswirkungen, die uns noch völlig unbekannt sind.Eine der wahrscheinlichsten Konsequenzen daraus ist das Auftreten vonKrebskrankheiten und Leukämien.577

Eine weitere Folge ist die genetischen Veränderung in der Nachkommenschaft.In beiden Fällen würde das DNA-System “ausfallen”, analog zu den Auswirkungendurch ionisierende Strahlen.Im Unterschied zu den ionisierenden Strahlen bestünde hier aber auch die Gefahrvom Auftreten neuer Infektionskrankheiten.NEUE INFEKTIONSKRANKHEITEN: Es ist bewiesen, dass die in diePflanzenchromosome (Canola) inkorporierten CaMV-Gene mit Infektvirenrekombinieren, um viel virulentere Viruskrankheiten zu produzieren.Ein disbezügliches experimentelles Modell über die Frage der Sicherheit dertransgenen Pflanzen, die transgene Viralgene wie das CaMV enthalten, wird vonGAL in einer Studie aus dem Jahr 1992 vorgelegt.(Gal S.: Agroinfection of transgenic plants leads to viable Cauliflower Mosaic Virus byintermolecular recombination, Virology, No.187, pp.: 525-533, 1992)http://www.mednat.org/alimentazione/Gal.pdfÜber die Rekombination von CaMV und verschiedenen Viren unter Miteinbeziehungdes Promotors siehe auch die 1990 durchgeführte Vaden Studie.(Ray Vaden: Recombination sites in Cauliflower Mosaic Virus DNAs; implications for Mechanismsof recombination, Virology, No.177, pp: 717-726, 1990)http://www.mednat.org/alimentazione/Ray%20Vaden%20.pdfAndere wissenschaftliche Untersuchungen weisen darauf hin, dass diese Retrovirenuntereinander DNA-Ketten mit anderer DNA und RNA mit anderer RNAaustauschen und so neue virale Infektionen erzeugen können.(Mol.Plant-Microbe Interactions 5, 48, 1992).Ähnliche Experimente haben ergeben, dass Veränderungen der Pflanzen tödlicheKrankheiten auslösen können, wie in der Studie von Green 1994 gezeigt wird.(Greene A.e.: Recombination between viral RNA and transgenic plant transcripts, Science, Vol.263, 11 march 1994)http://www.mednat.org/alimentazione/Greene.pdfDurch die Verwendung des CaMV Promotors 35S zur Produktion von RNA Viren,die sich sonst in der DNA der Pflanzen nicht ausbreiten könnten, sind nun höchstgefährliche, aus normalen RNA-Viren produzierte virale DNA-Ketten häufig in denPflanzen (GVO-Pflanzen) verbreitet. Aber von da können sie auch in die DNA von578

Tieren (Mensch eingeschlossen) oder in jene von Bakterien und /oder Virengelangen.(Boyer J.C.: Infectious transcripts and cDNA clones of RNA Viruses, Virology, No. 198, pp.: 415-426, 1994)http://www.mednat.org/alimentazione/Boyer.pdfDer CaMV Promotor geht also mit Infektionsviren eine Rekombination ein und ruftdabei neue, virulente Krankheiten hervor.Das CaMV Virus und seine Promotoren 19S und 35S können Gene der DNA derGast-Pflanze, des Gast-Tieres oder eines Gast-Bakteriums oder eines anderen Virus(vorausgesetzt ein DNA-Virus) inkorporieren und so neue, virulente Krankheitenerzeugen.Im letzten Fall (DNA-Virus), kann es zu einer Rekombination des CaMV mit denDNA-Viren von Insekten kommen und sich so in den Zellen der Insekten ausbreiten.(Zuidema D.: J.Gen.Vir. 71, pp.312, 1990). http://www.mednat.org/alimentazione/Zuidema.pdfEs ist also durchaus plausibel, dass ein großer Teil der menschlichen Bevölkerungsich durch den Konsum von Tomaten, die mit CaMV gentechnisch verändert wurden(in Rekombination zum Beispiel mit dem menschlichen Hepatitis B-Virus) mit einemVIRUS infizieren kann, das in der Folge auch auf Insekten (z.B. Steckmücken)übertragen werden kann.(Allison R.F.: Recombination in plants expressing viral transgenes, Seminars in Virology, Vol. 7,pp.: 417-422, 1996)http://www.mednat.org/alimentazione/Allison.pdf(Wintermantel W.M.: Isolation of recombinant viruses between Culiflower Mosaic Virus and aviral gene in transgenic plants under conditions of moderate selection pressure, Virology, No. 223,pp.: 156-164, 1996)http://www.mednat.org/alimentazione/Wintermantel.pdf(Latham J.: GM Gene Flow (B): Horizontal gene transfer of viral inserts from GM plants toviruses, Technical paper, February 2004)http://www.dirittolibertadicura.org/images/OGM/latham.pdf(J.T.Dessens : Cauliflower mosaic virus 35S promoter-controlled DNA copies of cowpea mosaicvirus RNAs are infectious on plants, Journal of General Virology, No.74, pp.: 889-892, 1993)http://www.mednat.org/alimentazione/Dessens.pdfEs existieren natürliche Retroviren, die in Tier und Mensch Leukämie, Lymphome,Sarkome oder Brustkrebs auslösen können (aus Kapitel 8 des Buches “DiventaMedico di te stesso” (“Werde dein eigener Arzt”).579

Diese sind sehr gefährlich, und eine zufällige Rekombination mit dem Promotor 35Sdes Cauliflower Mosaic Virus muss als höchst wahrscheinlich angesehen werden,wenn GVO-Pflanzen erst einmal in die Ernährung von Tieren und/oder Menscheneingeführt worden sind.Erforschung von GVO-Retroviren in menschlichen TumorenAls dringend notwenig erachtet wird die Erforschung an Krebspatienten bezüglich des Nachweiseseiner eventuellen Hybridisierung zwischen Polysomal-RNA (wahrscheinlich GVO-viralenUrsprungs, von veränderten Onkorna-Viren zur Herstellung von GVO-Nahrungspflanzen) aus denTumoren von Patienten, die sich von GVO-Nahrungsmitteln ernährt haben, und der DNA, die ausdenselben, für die GVO-Produktion modifizierten Onkornaviren durch Reverse Transskriptase imLabor synthetisiert wurde.Anmerkung: All dies erfordert jedoch den Zugang zu vertraulichen, vielleicht auch Patentgeschützten Informationen, bezüglich der Modelle von Retroviren, die von den GVO-Multisverwendet werden und bezüglich der an ihnen von eben diesen Unternehmen vorgenommenenVeränderungen, bevor die GVO-Pflanzen in den Handel kommen.Viel schwieriger ist es, tumorigene DNA-Viren ausfindig zu machen, die von den GVO-Multis zurDNA-Veränderung der Nahrungspflanzen verwendet werden, denn diese Viren (Poxviren,Herpesviren, Papovaviren, Adenoviren) sind im Unterschied zu den Onkorna-Viren im Blut oder imUrin des Patienten nicht feststellbar.Erwiesen ist hingegen, dass im Zytoplasma von infizierten und mit diesen DNA Viren modifiziertenTumorzellen von Säugetieren ein kleiner, höchst spezifischer Teil einer Boten-RNA übrig bleibt,der weder in normalen Zellen, noch in von anderen Arten onkogener DNA-Viren infiziertenTumorzellen zu finden ist.Es geht also darum, eine eventuelle Hybridisierung festzustellen zwischen dieser Boten-RNA(wahrscheinlich GVO-viralen Ursrungs, d.h. von modifizierten DNA-Viren stammend, um GVONahrungspflanzen zu erzeugen) die aus dem Zytoplasma von Tumorzellen von Patienten, die sichmit GVO-Nahrung ernährt haben, stammen, und der DNA, die aus denselben, zur Herstellung vonGVO modifizierten DNA-Viren im Labor synthetisierter wurde.Auch hier ist jedoch der Zugang zu vertraulichen, vielleicht auch Patent geschützten Informationenerforderlich, bezüglich der Modelle von DNA-Viren, die von den GVO-Multis verwendet werdenund bezüglich der an ihnen von eben diesen Unternehmen vorgenommenen Veränderungen, bevordie GVO-Pflanzen in den Handel kommen.Eine aus der Bildung von hybrider radioaktiver DNA ( 32 P) ersichtliche, positive Hybridisierungweist auf die Präsenz von viralen DNA Sequenzen in den veränderten Zellen hin. (Green, PerspectBiol. Med., 1978).580

Die Zurückhaltung von InformationenDie multinationalen Unternehmen überschwemmen die Welt mit “geheimgehaltenen” GVO, oder besser gesagt mit GVO, von denen man die an ihnenvorgenommenen Änderungen nicht kennt, weil sie durch das Industriegeheimnisgeschützt sind.Stehen jedoch keine Basisinformationen zur Verfügung, können folglich auch keineAnalyse- und Kontrollmethoden entworfen werden.Die Angelegenheit ist extrem ernst, denn diese GVO werden in den USA und inanderen Ländern, in denen die Produktionsketten nicht nach GVO-frei getrenntwerden, produziert und die Exporte könnten deshalb kontaminiert sein.Was können wir also tun?Zunächst einmal Informationen einholen, und zwar beim Ist. Superiore di Sanità(Höheres Institut für Gesundheitswesen), beim Istituto Zooprofilattico in Rom, beimLandwirtschaftsministerium und bei der Europäischen Kommission und eineParlamentarische Anfrage und Untersuchung starten.Die Europäische Kommission fördert jedoch die Genehmigung solcher GVO zuLebensmittelzwecken in Europa, und droht anderenfalls mit einem komplettenEinfuhrstopp aus den USA…So als würde man sagen: Da sie uns die GVO sowieso versteckt schicken,genehmigen wir sie halt…so können wir sie vielleicht kontrollieren…Es ist aber auch sehr wahrscheinlich, dass eine politische Aktion, kraft desVorsichtsprinzips des Maastrichtvertrages, die Patentierbarkeit der GVO und jedeForm von „Industriegeheimnis“ für genetische Manipulation platzen lassen könnte.Auch weil derartige “Geheimnisse”, außer importierten Nahrungsmitteln auch dasSaatgut betreffen könnten…und eine irreversible und wahllose Kontamination dereuropäischen Landwirtschaft einleiten würden.581

PUNKT FÜNF DER GVO-BEDROHUNG:Intoxikation durch Gifte, die von transgenen Pflanzen synthetisiert wurdenAnhaltende Intoxikation von Nahrungsmitteln aufgrund toxischer insektiziderSubstanzen, die in den Pflanzen enthalten sind, um sie resistenter gegen Parasiten wieden Bacillus thuringiensis zu machen, was möglicherweise zu einer Zunahme vonKrebskrankheiten, Fehlgeburten, genetischen Mutationen in der Nachkommenschaft,Syndromen erworbener Immunodefizienz, degenerativen, von toxischen Substanzenausgelösten Krankheiten, etc führen wird.Es wurde beispielsweise bewiesen, dass GVO-Mais bei Schafen und WiederkäuernVerletzungen der Mundhöhle hervorruft.Diese Studie aus dem Jahr 2003 zeigte, dass die Aufnahme von GVO Mais dieMundhöhlenwand beschädigt und wird mit dem unerklärlichen Tod vonVersuchstieren in Zusammenhang gebracht: es handelte sich dabei um Schafe undWiederkäuer.(Duggan et al, Fate of genetically modified maize DNA in the oral cavity and rumen of sheep,British Journal of Nutrition, 89(2): 159-166, 2003)http://www.mednat.org/alimentazione/Duggan_GMO_Mais.pdfPUNKT SECHS DER GVO-BEDROHUNG:Gefahr von weltweitem Mangel an natürlichen Pflanzen aufgrund der“TERMINATOR”-TechnologieÜbergang zu “heimischen” Naturarten von Weizen, Reis, Mais, Kartoffeln,Hülsenfrüchten, die nicht mehr in der Lage sind, sich aufgrund der“TERMINATOR”-Technologie selbst zu reproduzieren, was durch die gekreuzteBestäubung hervorgerufen wird und mit dem unwiederbringlichen Verlust auch fürdie heute zur Ernährung des Menschen verwendeten natürlichenLebensmittelpflanzen verbunden ist, denn diese werden von den transgenen Genenaus den Anbaugebieten mit transgener Landwirtschaft (GVO) vom Typ„TERMINATOR“ kontaminiert werden. Von daher also besteht die potentielleGefahr, dass wir in Zukunft einen weltweiten, unkontrollierten Mangel an natürlichenPflanzen zu verzeichnen haben werden, da es auf der Welt keine ausreichendenMengen an Weizen, Reis, Mais, Hülsenfrüchten „natürlicher“ oder zumindest „von„NICHT-TERMINATOR“ –Art geben wird.582

PUNKT SIEBEN DER GVO BEDROHUNG:Transgene Veränderungen der natürlichen PflanzenWir befinden uns durch die gekreuzte Bestäubung vor einem Übergang zunatürlichen, “heimischen” Pflanzenarten, die künstliche toxische Substanzen wie z.B.den “Bacillus thuringiensis” oder Substanzen anderer Art enthalten, was mit einerpotentiellen Gefahr auch für die heute in der Pflanzenheilkunde verwendetenmedizinischen Pflanzen und Kräuter verbunden ist, denn auch diese werden von dentransgenen Genen aus den Anbaugebieten der transgenen Landwirtschaft (GVO)kontaminiert werden.PUNKT ACHT DER GVO-BEDROHUNG:Unwiederbringlicher Erbgutverlust der natürlichen PflanzenWir werden ein graduelles und irreversibles Verschwinden der biologischen Vielfaltd.h. der normalen natürlichen Flora erleben: Ein Phänomen, das sich in den USAschon aufgrund der modernen Anbaupraktiken manifestiert, die die transgeneMonokultur (GVO) im Gegensatz zum differenzierten Anbau fördert. Der transgeneAnbau wird in der Tat eine enorme Gefahr für Gebiete mit hoher Biodiversität (mitnatürlichen Genomen) darstellen: Der transgene Fluss von den modifizierten Pflanzenzu den natürlichen Pflanzen wird unvermeidlich sein, wenn das numerischeVerhältnis zwischen Anbauflächen von künstlichen Pflanzen und denen natürlicherPflanzen zugunsten der ersteren ausfallen wird, und es so zu einemunwiederbringlichen Verlust eines Großteils des Erbguts aller auf der Weltexistierender Pflanzen kommen wird. Derzeit sind von den insgesamt 600.000 –800.000 geschätzten Pflanzenarten ca. 442.000 klassifiziert.Der Kern der Sache ist:Zahlreiche Pflanzen sind im Laufe der letzten Jahre schon verschwunden, daLandwirte die natürlichen Pflanzen zugunsten von Varietäten künstlicher, d.h.genetisch veränderter Pflanzen aufgegeben haben. Diese sind in ihrem Genomuniform, versprechen hohe Produktionserträge (mit geringem Vitamingehalt), sind insich krank (weil sie ohne Zugabe von Pestiziden nicht überleben können), ausmarktwirtschaftlichen Gründen steril, und schließlich sind sie genetisch manipuliert,um gegen Insekten und andere Tiere resistent zu sein. Sie sind nämlich fähig, selbstGifte, d.h. toxische Substanzen zu produzieren, die am Ende von den Zuchttieren undvom Menschen selbst als Nahrung aufgenommen werden.583

Sogar in den Wäldern ist die genetische Vielfalt von einem Verlust ihres Habitatsbedroht, und zwar nicht nur aufgrund falscher Abholzungsmethoden, sondern auchdurch die Kontaminierung des natürlichen Erbgutes durch die Pollen der GVO-Pflanzen.Die transgenen Produkte stellen gerade dadurch, wie sie hergestellt werden, einengewaltigen Anstoß dar, um die Merkmale der Einseitigkeit der Monokulturen zubetonen und daher das Verschwinden des natürlichen, nun seit hunderten MillionenJahren existierenden Erbguts verursacht. In mehr oder weniger naher Zukunft werdenwir also all diese Pflanzenvielfalt (auch von Lebensmittelpflanzen) nicht mehr haben,die für jedes nationale und lokale Gebiet charakteristisch ist.Die durch die von den großen GVO-Saatgutfirmen erzeugten Hybride (die sichunvermeidlicherweise mit den in der Natur vorkommenden Varietäten kreuzenwerden) ausgelösten genetischen Umweltkontaminierungen, werden zu einemVerlust des natürlichen Erbguts (das in keinster Weise wieder erlangt werden kann)führen, zum Verlust all dieser besonderen Merkmale, die im Laufe von langenAnpassungsprozessen an die verschiedenen Umweltbedingung in das Pflanzengenomeingegangen sind.Ein solcher Verlust ist heute sogar für natürliche Lebensräume wie die Wälderschwerwiegend. Im Grunde genommen ist die Grundlage der menschlichenBiochemie selbst in ihrer innersten Essenz (in der menschlichen DNA) durch dieleichtsinnige Verwendung dieser künstlichen Pflanzen bedroht, ohne irgendeineMöglichkeit, das Erbgut von über 440.000 klassifizierten Pflanzenarten (von über600.000- 800.000 geschätzten) wieder zu erlangen, und von denen ein großer Teil imLauf von wenigen hundert Jahren verschwinden wird, an der Wurzel unterminiertvon den durch den Menschen ausgelösten genetischen Schäden.584

Multinationale Agrar- und Ernährungsunternehmen (Biotech, GVO)Seit einigen Jahren erleben wir das Entstehen von multinationalen Großkonzernen,die sich selbst als “Multinationale Unternehmen für Lebenswissenschaften”definieren und auf dem pharmazeutischen Markt, im Agrarbusiness (Saatgut undPestizide) und im Veterinärbereich aktiv sind.Diese Sektoren sind an und für sich untereinander verschieden, das verbindendeElement stellt die Verwendung von Biotechnologie (GVO) in der Produktherstellungdar.Diese Multis verfolgen äußerst skrupellose und aggressive Wirtschaftsstrategien: Seitden 90er Jahren sind sie dabei andere Unternehmen, darunter auch bedeutende,aufzukaufen.Einer dieser multinationalen Konzerne, Monsanto, hat im Laufe weniger Jahre miteiner Investition von 10 Mrd. Euro (aktueller Wert) Asgrov, Agracetus, De Calb undCargill erworben.Eine andere Gruppe, Dupont, hat mit einer Investition von ca. 8 Mrd. Euro (aktuellerWert) das Unternehmen Pioneer aufgekauft.Diese Investitionen scheinen einer antiökonomischen Logik zu folgen: Sie zahlen fürdie Firmen, die sie übernehmen, einen überhöhten Preis in Bezug auf ihren realenWert, so als ob sie eher einen potentiellen Konkurrenten ausschalten als kurzfristigeinen wirtschaftlichen Erfolg erzielen wollten.Neben den Firmenkäufen gibt es dann auch noch die Fusionen: aus Ciba Geigy undSandoz entsteht Novartis (Umsatz von 20 Mrd. Euro (aktueller Wert) im Jahr 1997-98).Aus der Fusion der französischen Rhone Poulenc mit der deutschen Hoechst entstehtAventis.Weiters entsteht in diesem Zusammenhang im Oktober 2000 die erste weltweiteGruppe auf dem Agrarchemiesektor, Syngenta, - als Ergebnis der Fusion desSchweizer Unternehmens Novartis (bekannt für seine Chemotherapeutika), mit deranglo-schwedischen Firma Astra-Zeneca (auch bekannt für ihre Chemotherapeutika),die einen Umsatz von 8 Mrd. Euro erwirtschaften wird. Nach der Fusion mitPharmacia & Upjohn, einem großen pharmazeutischen Unternehmen (ebenfallsbekannt für seine Chemotherapeutika), beschäftigt sich Monsanto nur mehr mitLandwirtschaft, wobei der Umsatz im Jahr 2000 5,5 Mrd. Dollar erreicht hat.585

Die heutige Situation stellt sich folgendermaßen dar: Sehr wenige multinationaleKonzerne (Syngenta, Monsanto, Novartis, Dupont, Aventis) halten 25-30% desSaatgutmarktes (aber über 90% Marktanteil bei transgenem Saatgut) und nach diesengroßen Gruppen gibt es nur mittlere und kleine verstreute Firmen, so dass manunweigerlich zum Schluss kommt, dass sich diese Tendenz in der Zukunft nurverstärken kann. Natürlich können Firmen mittlerer Dimension der Konkurrenz derWirtschaftsriesen nicht standhalten. Das augenscheinliche Ziel ist die Umstellung destraditionellen Saatgutsektors auf Biotechnologie (also GVO). Das Ungeheuerlichean der Sache ist aber, dass wir immer wieder auf dieselben Namen stoßen: dieselbenNamen finden wir auf dem Pestizidsektor, wo dieselben Unternehmen 55% desMarktanteils halten, und vor allem auf dem pharmazeutischen Sektor, wo wiederdieselben multinationalen Unternehmen eine dominierende Position einnehmen.Multinationale Konzerne im chemisch-pharmazeutischen Bereich (Big-Pharma)Die chemisch-pharmazeutischen Weltkonzerne haben eine unglaubliche,kometenhafte Entwicklung erfahren und sind heute in äußerst gefährlicher Weise anden Agrar- und Ernährungsbereich gekoppelt:Die chemisch-pharmazeutische Industrie in Europa entstand in der zweiten Hälfte des19. Jahrhunderts: In vielen Fällen handelte es sich um Farbenindustrie, die sich nachder Abspaltung von der Basischemie in die Richtung neuer und Erfolgversprechender Gebiete der spezialisierten Chemie für wirtschaftlicheSchlüsselsektoren hin entwickelte.In den Jahren vor dem Zweiten Weltkrieg entstand ein internationales Pharmakartellmit Sitz in Deutschland, das die chemische und pharmazeutische Industrie der ganzenWelt beherrschte. Dieses Kartell hatte seine Aktivitäten auf 93 Länder ausgedehntund in jedem dieser Länder stellte es eine bedeutende wirtschaftliche und politischeMacht dar. Das Kartell war als IG Farben bekannt.IG Farben sollte schließlich im zweiten Weltkrieg zur tragenden Säule von Hitlerschemischer Produktion werden – mit der Herstellung von potenten Sprengstoffen,Giftgasen und dem entsetzlichen Zyklon-B, der tödlichen Substanz, die die Nazis inden Vernichtungslagern einsetzten.Dennoch hatte vor dem Krieg, nämlich 1928, der amerikanische Monopolist undIndustrielle John D. Rockefeller eine Industriekonzentration zwischen seineminternationalen Imperium mit Sitz in Amerika und der IG Farben bestimmt, und sodas größte und mächtigste Pharmakartell, das die Welt je gesehen hatte, ins Lebengerufen.586

Das Nürnberger Militärgericht erklärte 1946/47, dass der Zweite Weltkrieg ohnedieses Petrochemische Kartell IG Farben nicht möglich gewesen wäre.Als Folge des Gerichtsurteils wurde die IG Farben in Bayer, BASF und Hoechstaufgeteilt und einige leitende Vertreter wurden wegen Krieg gegen das internationaleRecht, wegen Völkermord, Ausbeutung und Plünderung öffentlichen und privatenEigentums in fremden Staaten und wegen anderer Verbrechen gegen die Menschheitverurteilt.Die Vorgeschichte des Unternehmens im Hintergrund des Zweiten Weltkrieges ist ineinem Buch von Joseph Borkin "The Crime and Punishment of IG Farben" (Dieunheilige Allianz der I.G. Farben. Eine Interessensgemeinschaft) dokumentiert.Nach dem Krieg hatte Deutschland dennoch wieder, nun mit seinen drei GigantenBayer, Hoechst und BASF eine wichtige Rolle inne, und das gemeinsam mit derSchweiz, wo sich in Basel Ciba, Sandoz und Roch entwickelten - alles Unternehmen,die sich bekanntlich auf dem Weltmarkt behaupten konnten.Die großen Fusionen begannen dann aber in den 90er Jahren: In Großbritannienfusionieren 1989 zwei große Pharmaunternehmen zur Smith Kline-Beecham und inder Folge geht dieses mit dem Unternehmen American Home zusammen(Jahresumsatz von ca. 25 Mrd. Euro).1993 kauft die schwedische Firma Pharmacia die italienische Farmitalia-CarloErba, fusioniert dann 1995 mit dem amerikanischen Unternehmen Upjon und dannnoch mit Monsanto, bevor sie vom Pfizer Konzern aufgekauft wird, der zuvor dieamerikanische Gesellschaft Parke Davis übernommen hat.1995 kommt es zur Fusion Glaxo- Wellcome (ca. 14 Mrd. Euro Jahresumsatz).1998 fusioniert Smith Kline - Beecham (ca. 62 Mrd. Euro Jahresumsatz) mit Glaxo-Wellcome, mit einem daraus resultierenden Kapital von über 90 Mrd. EuroJahresumsatz.In der Zwischenzeit fusionieren die englischen Imperial Chemical Industries mit demschwedischen Konzern Astra und gründen somit Astra-Zeneca.Und weiterhin handelt es sich um Fusionen zwischen denselben Pharmaunternehmen,die auf ein und demselben Markt präsent sind: Sandoz und Ciba Geigy (Novartis,1996), Astra- Zeneca (1998).Diese Kolosse entstehen jedoch nicht aus dem Bedürfnis heraus, einen Vorteil fürPatienten zu schaffen, sondern allein aus dem Bedürfnis heraus, Monopole zukreieren und immer größere Profite zu erzielen.587

Die neuesten Daten:Juni 2002: Bayer übernimmt Aventis; diese Vereinbarung erlaubt Bayer den Einstiegin den GVO-Saatgut-Markt. Durch die Fusion entsteht das Unternehmen BayerCropScience, das sich nunmehr aus drei Haupthandelsgruppen zusammensetzt: CropProtection, Bio Science und Environmental Science.Juni 2005: Monsanto übernimmt Sementis.Die AllianzMan kann also behaupten, dass die zwei Angelpunkte der Wirtschaft und des Lebensjedes einzelnen Individuums, die Landwirtschaft und die Pharmazeutik, imWesentlichen von einem, aus einer Handvoll multinationaler Konzerne bestehendenOligopol kontrolliert werden.SCHLUSSFOLGERUNGWir befinden uns nun an einem Scheideweg: Entweder wir akzeptieren diebiochemischen Modifizierungen an Pflanzen und damit die immensen Schäden fürdie menschliche Gesundheit, oder die demokratischen Institutionen unsererGesellschaft beziehen eine klare Stellungnahme gegen die multinationalen GVO- undchemo-pharmazeutischen Konzerne, die in ihrer Allianz hinter derunverantwortlichen Invasion der Welt mit den GVO stecken.Die Lösung ist einfach, doch wir haben nur 4 Monate Zeit, um die GVO aufzuhalten,was Prof. Altieri so treffend und zurecht als ein IRREVERSIBLES Ereignisbezeichnet:1) Absolutes Anbauverbot von GVO Pflanzen2) Absolutes Verbot von Freilandversuchen (Gefahr von horizontalemGentransfer)3) Aufwertung des Biologischen Landbaus (der darüber hinaus bessere Erträgeerzielt)4) Schutz der Biodiversität, besonders mit der Wiedereinführung der Freiheit fürBauern, Saatgut untereinander auszutauschen.Wenn das alles nicht geschieht, so fordern wir ein Gerichtsverfahren - Europa gegendie GVO-Multis- , das im Herzen Europas, unter deutschem Vorsitz stattfinden soll!DankeENDE588

Allegato 20“La minaccia OGM (Organismi Geneticamente Modificati) sui modelli alimentaridi accompagnamento alla terapia immunitaria e detossificante”.Relazione presentato al SANA di Bologna il 13 settembre 2008http://www.fiorigialli.it/dossier/view/1_biononbio/1317_la-minaccia-ogm-suimodelli-alimentari-di-accompagnamentohttp://www.circolovegetarianocalcata.it/?s=Relazione+OGM+Sana+Bologna+http://www.greenplanet.net/index.php?option=com_content&view=article&id=22028---------------------------------------SANA – BOLOGNA 13 /9/08. English, Espanol, Deutsch, Italiano athttp://www.erbeofficinali.org/dati/nacci/index.php---------------------589

Allegated 21SEIKOAmerica's disastrous health care system is heaving the country head-first into near-certain economiccollapse. Just about everybody's either financially strained or going broke due to spiraling healthcare costs: the people, the employers, state governments and even the federal government.Multinational corporations are fleeing the United States due to health care costs, taking jobs andeconomic productivity with them. Meanwhile, 50 percent of personal bankruptcies in the U.S. aredue to medical expenses.But not everybody's doing badly. The drug companies, surgeons, medical specialists, healthinsurance companies and private hospitals are making out like bandits, raking in multi-million dollarCEO salaries and -- I'm not making this up -- greater than 500,000% markups on prescription drugs.And while the American people get sicker, the drug companies, insurance companies and manyhealth "care" providers (it's really more like "sick care providers") are rolling in cash. Drugcompanies are now among the richest corporations in the world, and they got there by inventingfictitious diseases, then selling drugs to people who mostly don't need them. See my CounterThinkcartoon, Disease Mongers, Inc. to learn more about this topic.Meanwhile, the American people are the most diseased people in the world among advanced nations.We spend more on health care than anyone, we pay the highest prices for medications, and we'reconstantly told that we have the best medical technology in the world. But if our health care systemis really so good, why do 50 million Americans have no health insurance? Why are hospitals literallydumping uninsured patients on the street, abandoning the sick to protect profits while our politiciansactually negotiate on behalf of Big Pharma to make sure Americans keep paying the highest prices inthe world for medications? (Click here to see our CounterThink cartoon on President Bush's pricenegotiations with drug companies.)What's wrong with America's health care system?SiCKO is a must-see documentarySiCKO creator Michael Moore answers that all-important question in his best documentary yet.Forget whatever criticism you may have heard about SiCKO -- this is a Michael Moore masterpiece:A courageous, impactful and outrageous documentary that exposes the arrogance of modernmedicine and the utter failure of America's corporate-controlled sick care system to provide decenthealth care to the people. Watching this movie will leave you either steaming mad or shedding tears(or both). It reveals the deep-rooted corruption in America's health care system and explains why thewhole system was actually designed to deny health care to the American people.I've been ranting about America's health care failures for years, and as I've consistently stated to theamazement of some, the health care corporations actually have a plan to keep people sick. There's nomoney in preventing disease, especially in the cancer industry. Click here to read my recent reporton the American Cancer Society's refusal to help prevent 77% of all cancers using affordable,scientifically-proven vitamin D supplements.In SiCKO, what Moore does very effectively is tells this story to a mass audience, weaving togetherthe emotionally-charged stories of American citizens who lost husbands, daughters and other family590

members to preventable disease, all thanks to intentional, well-planned payment denials by healthinsurance companies. In one segment in the film, he features archival footage of former PresidentNixon, who strongly approves of a new 1970's health care concept called the "HMO" where themore patients are denied health care services, the more money the hospitals and health insurancecompanies rake in!In contrast to all this, Moore shows us the universal health care systems in countries like Canada, theUK, France and even Cuba... all countries where health care is free to everyone. It's called universalhealth care (or "socialized medicine"), and it's a system followed by nearly every modern nation inthe world... and even some not-so-modern nations. Only America practices medicine in the DarkAges, tied to a hopelessly corrupt system of financial exploitation and monopoly price controls,where Big Pharma gets richer, the FDA gets more powerful, and the American people get the shaft.See my CounterThink cartoon, The Disease Economy, for a visual representation of this mess we'rein, or read my book Natural Health Solutions and the Conspiracy to Keep You From KnowingAbout Them to see just how evil and corrupt our modern health care system really is.Why Moore is being so vicious attackedMoore, as usual, is being targeted by all sorts of critics who would like nothing better than to see thisguy disappear and stop rocking the Good 'ol Boys boat that seems to be floating just fine in America(as long as you're part of the wealthy elite, anyway). For starters, U.S. government officials areinvestigating Moore for violating travel restrictions to Cuba. And why? Because Moore gathered adozen Americans who were denied health care in the U.S. and brought them to Cuba where theyreceived free, quality health care in a modern Cuban hospital.The message is hard to miss: Cuba takes better care of its citizens than America does. In fact, Cubais willing to take care of a few American citizens that America abandoned! That kind of "in-yo-face"embarrassment to U.S. officials isn't appreciated much in police-state America these days, wherepractically anyone who dares question the wisdom of the government is branded a terrorist. Moore isclearly being targeted not merely because he took some 9/11 heroes to Cuba and got them healthcare, but because he dared to make it all public. Humiliating the King is a quick way to find yourhead on a chopping block. Just ask all the scientists who publicly disagree with the BushAdministration's hopelessly politicized view on climate change...Other critics of Moore are either the greedy, corrupt corporations impacted by his film (drugcompanies, health insurance providers, hospitals and so on) or juvenile stay-at-home back-seatInternet critics who don't like Moore for the simple fact that he dares to stand up and say "TheEmperor Has No Clothes!" Nearly all the criticism leveled against Moore is without substance.People attack Moore personally, but they won't dare debate what he's presenting in the movie. Why?Because Michael Moore is right. America's health care system is an embarrassment to the nation,and to the world. It's so bad that most informed world citizens wouldn't be caught dead in thiscountry, unless of course they actually visit America and have an accident that lands them in theU.S. health care system.Personally, I opted out of the American health care system long ago. I'm a holistic nutritionist, and Iexercise, eat right, get lots of sunshine and gorge on superfoods and raw berries. I have no need for adoctor, or a pharmaceutical, or a health insurance policy. I don't get annual physical exams, and Ihave zero risk of cancer, heart disease, diabetes or other common health conditions. (I posted myhealth statistics at www.HealthRanger.org if you want to see my blood workup.)591

At the same time, I realize that not everybody is in such a fortunate health position. Most peoplesimply don't take care of their own health, and while I could argue for days about the need for morepatient responsibility alongside corporate responsibility, the fact is that relentless advertising fromdrug companies and food manufacturers has bred a mindset of disease, junk food consumption,pharmaceutical dependence and patient victimization. We have a health crisis in this country, and it'sgoing to take genuinely radical reforms to turn this around and save America from a financialwipeout exacerbated by runaway health care spending.What's missing from SiCKOThe material that's in SiCKO is hard-hitting, and it accomplishes what it sets out to do. But there'ssomething missing from the film: A serious discussion about how a nation can prevent disease usingnutrition, medicinal herbs, sunshine, clean water, avoidance of toxic chemicals, smart dietarychoices, banning the advertising of junk foods and pharmaceuticals, and so on. Of course, that's notreally what SiCKO set out to do, and this topic would require another film all by itself, butpersonally I wouldn't have minded a stronger nod towards solving our nation's health care problemsthrough genuine prevention (rather than the current policy which is basically centered aroundwaiting for everybody to get sick and then treating their symptoms while ignoring the true causes oftheir disease).Of course, it might be tricky for Moore to argue for disease prevention given that he is obviously notthe poster boy for ideal physical health. But he never claims to be. So the critics who attack Moore'sown personal health are missing the whole point of the film. Moore is simply pointing out what'swrong with America's health care system, and he does so brilliantly and convincingly, regardless ofhis own personal health status. And besides, if you want to argue about the health of "experts," justwalk into any hospital and take a look at the health of all the people who work there. Many aren'tany healthier than Moore, and they work in the industry! The average lifespan of a U.S. doctor isless than a Cuban peasant. That's not a joke.Regardless of Moore's present physical fitness challenges, he's obviously operating with a greatdegree of healthy skepticism about the way the U.S. operates today. Moore is an independent thinkerwho simply refuses to follow the crowd, and with this film, he's doing the job that the Americanpeople should have been doing all along -- questioning the sanity of our health care system. Butsadly, the truth is that most Americans are sheeple who just follow the herd and do what they're told.A recent poll revealed that nearly 45% of Americans still trust the FDA! That's astounding, giventhat I've solidly established the Food and Drug Administration is far more dangerous to the healthand safety of the American people than all the terrorists in the world. To learn more, read my articleThe lawlessness of the FDA, Big Pharma immunity, and crimes against humanity.How will SiCKO play?I think SiCKO's timing is perfect, and I think the movie will be a significant factor in the upcoming2008 elections. Those politicians who run on a platform of radical health care reforms are likely topick up a lot more support than those unwise enough to try to defend the current system.This is a tough call for Republicans, since most Republicans support Big Pharma and the corporatecontrol of modern medicine, usually at the expense of the people. Democrats, though, are also onBig Pharma's payroll, as was obvious with the recent voting record on the FDA Revitilization Actco-sponsored by Sen. Edward Kennedy. The truth is, Big Pharma owns virtually all the politicians inWashington (except Rep. Ron Paul, of course).592

The movie will definitely get America talking about serious health care reforms. But as I've pointedout in a previous article, Where's the Health In Health Care Reform?, almost nobody is consideringproposals that would genuinely solve the health care problem in America today. You can't "treat"your way out of a nation that has become so over-drugged, over-fed and over-diseased that even thelittle children are now being put on speed (also called "Ritalin"). Nearly 50 percent of Americanadults are now taking pharmaceuticals, most of which are utterly unnecessary from a medical pointof view. Drug advertising has taken over the media, the FDA has suppressed natural alternatives, andthe American Medical Association continues to peddle such health nonsense that it's amazing theAMA hasn't yet been invited to join the Smithsonian's Museum of Outdated American History.The American Cancer Society, in my opinion, is a supremely corrupt, big-business front group thatactually takes steps to ensure more cases of future cancer by "preventing prevention," the AmericanDiabetes Association takes money from candy and soda manufacturers, and the AmericanPsychiatric Association is so steeped in Big Pharma money that they've practically becomeinseparable. (Click here to see my CounterThink cartoon on this topic.)The future of America looks dimClearly, something has to change in this country if we're going to survive as a nation. Under thecurrent system of massive debt spending, widespread political corruption, war mongering and healthcare failures, the United States of America will simply not survive another generation. No nation thatabandons the health of its people can expect to have a future. As Moore points out, however, there isa chance to save America, but only if we make significant changes starting now.Truly radical changes must be put into place. I've offered many suggestions in a popular article, Thehealth care reform legislation that Congress should pass, but won't. Lawmakers, you see, have nointerest in actually saving America from financial demise. They're only concerned about the nextelection, and raising campaign reelection funds means kow-towing to the interests of the powerfulcorporations that really run Washington.Personally, I don't see that meaningful reform is possible under the current system of politics inAmerica. The Big Business sick care industry has a stranglehold on the American political system,and the whole ugly thing will mostly likely have to collapse and be rebooted before we'll seesignificant change.And make no mistake: that's what's coming. I predict America will not survive its health care crisis.It won't be the first empire to crumble from arrogance and corruption. In fact, it will join a long (andgrowing) list of civilizations that have risen and fallen, securing its place in the pages of history asyet another imperialist nation that thought it could rule the world while abandoning the needs of itsown people.The bottom line on SiCKOIt's a must-see documentary. It's surprisingly even-handed and well grounded, never resorting tounsubstantiated claims merely to shock the audience. In fact, as a person who has been writing aboutAmerica's health care problems for four years, I didn't detect a single false statement in the film. It'sall true, and it's pretty damn scary. Go see it. It opens on June 29th.And if, like one person featured in the film, I ever have to choose between reconnective surgery formy middle finger at $60,000 vs. my ring finger at $12,000, I'll choose to have my middle finger593

sewn on first just so I can visually demonstrate to U.S. Senators precisely how I feel about America'shealth care system today.###About the author: Mike Adams is a natural health author and technology pioneer with a mission toteach personal and planetary health to the public He has authored more than 1,500 articles anddozens of reports, guides and interviews on natural health topics, reaching millions of readers withinformation that is saving lives and improving personal health around the world. Adams is anindependent journalist with strong ethics who does not get paid to write articles about any product orcompany. In 2007, Adams launched EcoLEDs, a manufacturer of mercury-free, energy-efficientLED lighting products that save electricity and help prevent global warming. He's also a notedtechnology pioneer and founded a software company in 1993 that developed the HTML emailnewsletter software currently powering the NewsTarget subscriptions. Adams volunteers his time toserve as the executive director of the Consumer Wellness Center, a 501(c)3 non-profit organization,and practices nature photography, Capoeira, Pilates and organic gardening. Known by his callsign,the 'Health Ranger,' Adams posts his missions statements, health statistics and health photos atwww.HealthRanger.org594

ALLEGATED 22 : Thirty Clinical Cases of Dr. Gonzales and Dr. IsaacCASE 1Patient IG: A 12+ Year Survivor of SARCOMAPatient IG is a 58-year old woman who in the summer of 1993 first noticed a mass above her rightear. After the lesion became chronically irritated by her eyeglass frames, in August 1993 she optedto have it removed. The nodule, measuring about 1 cm in diameter, was found consistent with“malignant neoplasm, probably metastatic.” The slides were sent for review at the Mayo Clinic,where the pathologist classified the cancer as an epithelioid sarcoma. A subsequent third review ofthe slides confirmed the diagnosis of epithelioid sarcoma.The patient then underwent a metastatic work-up. A bone scan in September 1993 revealed:“Single abnormal focus of uptake in the left occipital-parietal region, worrisome for metastaticneoplasm.”A skull series the same day showed a “9 mm geographic lucency in the left occipital bone, possiblyrepresenting a calvarial metastasis.” The report of a CT scan of the head a week later stated:“Images of the skull demonstrated one small lytic area…in the left occipital bone…It measuresunder a centimeter in size. It is in the medullary space of the bone but appears to affect the cortexalso. No soft tissue component is noted.”A CT scan of the neck and chest showed a probable right thyroid cyst, and two areas of decreasedattenuation in the liver compatible with either cysts or metastatic disease.IG then met with a head and neck surgeon, who proposed wide excision with removal of much ofher jaw followed by reconstruction. But when she was told she most likely would die of her diseaseanyway, she refused surgery. After investigating alternative approaches to cancer, she learned ofour therapy and consulted with Dr. Isaacs in late September 1993. She thereafter followed herprogram diligently.In June 1994, nine months after she began her nutritional regimen, she noticed a lump above herright ear in the same location as the original tumor. The nodule stabilized for two years, before itwas resected in August 1996. The pathology report describes once again an epithelioid sarcoma.After Dr. Isaacs made some adjustments in the protocol, IG continued her therapy faithfully asbefore.Over the years, IG has been very compliant with her regimen, and enjoyed improvement in heroverall energy and sense of well being. Since the surgery of 1996, the disease has not recurred.When last seen by Dr. Isaacs in August 2006 she was in good health with no visible evidence ofcancer.Epithelioid sarcomas tend to be fairly aggressive. If localized, as with most sarcomas, surgery canbe curative, but once metastatic, survival is usually measured in months. A review of epitheloidsarcomas reported that “Median post-distant metastasis survival was 8 months.”We don’t think the lesion that appeared after she began her therapy indicates global treatmentfailure. As mentioned previously, we find at times that tumors will recur in areas of prior surgery,though nowhere else. We suspect that in areas of such tissue disruption, the resulting fibrosis andscarification compromise blood supply to the area, and create a protected area where residualcancer cells can grow unhindered. We suspect such a scenario in this patient’s case. Regardless,today, 13 years from her original diagnosis of metastatic cancer she is in excellent health with noclinical evidence of her disease.595

CASE 2Patient AL: A 10-Year Survivor of OVARIAN CANCERPatient AL, prior to developing cancer, had a long history of neuro-muscular symptoms dating to1979, when she first developed a mass in her left calf, associated with muscle pain, atrophy, andnumbness. In the intervening years, as the symptoms worsened, she consulted numerous physiciansat numerous centers. Though multiple muscle biopsies had all been unrevealing, she wasnonetheless treated empirically and unsuccessfully with a variety of drugs including prednisone. In1985, she sought another evaluation at the Mayo Clinic, where a muscle biopsy confirmedpolymyositis. After she was also diagnosed with motor and sensory neuropathy, type II, AL begananother course of prednisone but with little improvement, followed by six months on Imuran. Thelatter drug did nothing for her disease, but did lead to weight gain, insomnia and anxiety.As her symptoms worsened, AL, who knew of my work from a family member, decided to seektreatment with me for her neuromuscular problems. When she first came to my office in 1989, shehad been off all medications for some three years, during which time her symptoms of weakness,nerve pain and numbness continued to progress. When I first saw her, she had no gynecologicalproblems other than the history of a hysterectomy for uterine fibroids.I designed a protocol to treat this patient’s muscle and neurological problems, without the highdoses of enzymes we use against cancer. Subsequently, AL complied well with her program, andwhen I saw her for a return visit in August 1989, she reported her condition that had worsenedwithout respite over the previous 10 years had improved significantly. She described a “20%”overall gain in motor strength and calf thickness, a marker her previous doctors had used to trackher decline. The proximal muscle weakness in both legs had reversed to the point she could standfrom a sitting position for the first time in years. However, on exam I detected a small pelvic massand told her she needed to follow up with a gynecological evaluation upon returning home.Some weeks later, in early fall, an ultrasound revealed a 7 x 8 cm cystic lesion posterior to thebladder. Then in early November 1989, at the Moffitt Cancer Center in Tampa, she underwentexploratory laparotomy and was found to have extensive malignant disease throughout her pelvisand abdomen. Her surgeon proceeded with bilateral oophorectomy, omentectomy, and extensivelymphadenectomy of pelvic, periaortic and precaval lymph nodes. The pathology report describes“Omentum diffusely infiltrated by papillary serous carcinoma” of ovarian origin, as well as tumorin both ovaries that involved both fallopian tubes. Cancer had infiltrated into all 21 of 21 nodesevaluated, and peritoneal washings were positive for “metastatic adenocarcinoma consistent withovarian primary.”After surgery, AL met with an oncologist who strongly recommended intensive chemotherapy, butshe decided to refuse all conventional treatment, instead choosing to begin the cancer version of mytherapy. At that point, I redesigned her regimen to include high doses of pancreatic enzymesthroughout the day.In December 1989 her oncologist wrote a summary note to me, which accompanied the records ofher recent hospitalization. In his letter, he states:“She is diagnosed as having a Stage IIIC Grade I papillary serous cystadenocarcinoma of theovary. I have recommended that she receive chemotherapy. She would be a candidate for GOGProtocol 104 intravenous Cisplatinum and Cyclophosphamide versus intraperitoneal Cisplatinumand Cyclophosphamide. Mrs.---- unfortunately did not wish to pursue the idea of chemotherapy…”She thereafter followed her program diligently for six years. By the mid 1990’s, her muscleweakness began to progress once again, making return trips to New York difficult, though shecontinued on the regimen and we worked together by phone. We last spoke in August of 1999, whenshe wrote after hearing me on the radio. She was 78 at the time, able to walk with a leg brace, andotherwise was doing fine, apparently cancer free nearly 10 years out from her diagnosis ofextensive ovarian malignancy.DeVita reports, regarding ovarian cancer patients such as this:596

“patients with stage III disease have a 5-year survival rate of approximately 15-20% that isdependent in large part on the volume of disease present in the upper abdomen…”In this patient’s case, the disease did extend into the upper abdomen at the time of diagnosis.Furthermore, these survival statistics refer to patients treated with aggressive chemotherapy, whichAL refused, choosing to follow only my regimen. Her prolonged disease free survival can only beattributed to her nutritional program.CASE 3Patient JR: A 13-Year Survivor of OVARIAN CANCERPatient JR is a 57 year-old woman whose father developed both rectal and primary liver cancer,and whose mother survived breast cancer before dying of pancreatic cancer. She herself had ahistory of gynecological problems dating back to 1981 when at age 31 she was first diagnosed withbilateral ovarian cysts. Over the years, her gynecologist followed her with sequential ultrasoundsand recommended surgery when she developed persistent severe pelvic pain. JR refused hissuggestion, instead deciding to treat herself with alternative approaches, including several visits tothe Hippocrates Institute, a live-in facility offering a raw vegetarian approach to various diseases.She believed her nutritional interventions did help her overall health, though the cysts did notregress.In March 1993, during a period of extreme personal stress, the patient herself felt that the cysts hadenlarged. An ultrasound at Johns Hopkins Hospital revealed:“…a large approximately 14 X 10 x 12 cm mass in the mid line pelvis….Multiple foci of hyperechogenicityare noted…Therefore, this mass likely arises from the left ovary.“…Within the right ovary, there are two hypoechoic regions and a focus of calcification…Thelargest hypoechoic region measures approximately 1.5 x 1.6 x 1.5 cm….”At that point, her gynecologist insisted she undergo exploratory surgery, but JR instead returned tothe Hippocrates Institute for a several week stay. Despite the aggressive dietary intervention, themass continued to grow.In mid-October 1993, JR returned to her gynecologist, with the large pelvic mass clearly evident.Another ultrasound revealed that the mass had grown considerably since March, now measuring"20 x 22 x 15 cm." The radiology report states “This has moderately increased in size since the lastexamination…A normal right ovary is identified….”JR then proceeded with surgery at Johns Hopkins Hospital after her physician agreed to removeonly the mass and the associated ovary, not the uterus or right ovary. During the procedure, shewas found to have a huge tumor that had penetrated into the recto-sigmoid area of the colon.Though the surgeon did preserve the uterus and right ovary, his resection was quite extensive asdocumented in the Discharge Summary:“The patient …underwent surgery on November ---1993, undergoing an exploratorylaparotomy…resection of ureterosacral tumors, resection of left parametria, omentectomy,resection of rectosigmoid, left common iliac node dissection and para-aortic lymph nodedissection…”The pathology report describes an enormous tumor, “measuring “17 x 12 x 7 cm” consistent with“Adenocarcinoma probably serous,” though the tumor was finally classified as a clear cell subtypeof ovarian adenocarcinoma. The lymph nodes appeared free of cancer, as did the right ovary. Sincethe disease appeared to be largely limited to the left ovarian mass, as big as it was and though thetumor had penetrated the colon, she was assumed to have “localized” stage I cancer.Postoperatively, JR met with an oncologist at Johns Hopkins who strongly recommendedchemotherapy. She initially agreed to the treatment, but after her discharge from Hopkins – withplans to return to start therapy - she then consulted with a second oncologist at George WashingtonUniversity Medical Center, who was less insistent about the need for immediate treatment. JR597

therefore decided to refuse conventional approaches, though she did agree to return for routinesurveillance. Note that a CA 125, a blood marker for ovarian cancer, was 16.1 at the time, withinnormal limits.After learning of my therapy, she first came to my office in January 1994 and subsequently followedher nutritional therapy faithfully. When she returned for her first follow-up visit in April 1994, threemonths after she had begun treatment with me, she reported feeling “better than I have in years,”with significant improvement in her energy, stamina and well being. Shortly after that session, sheexperienced mild midcycle bleeding and consulted her local gynecologist, who felt a mass in thepelvis on exam. JR detailed the interaction with her oncologist in a note to me in late April:“I continue to feel great. What is so frustrating, though, is going to the doctor and being toldsomething might be wrong when I am feeling the best I have in years. I think that on some level, Dr----(the oncologist) hopes that something will be wrong so that he can prove to me that my programwill not work.”Despite the concern, an ultrasound in May showed no lesions on the ovary, no fibroids, and afollow up exam with her gynecological oncologist was normal. Subsequent CA 125 tests all fellwithin the normal range.JR continued doing well until mid-December 1995, nearly two years after she had started hernutritional program, when she developed sudden onset abdominal pain associated with nausea andvomiting. When the CA 125 came back elevated at 52 (normal less than 36), her oncologistimmediately suggested radiographic studies. Before any testing could be done, her symptomsbecame so severe she went to the local emergency room, where an intestinal obstruction was ruledout. After intravenous hydration, she improved and went home, with a diagnosis of gastroenteritis.A repeat CA 125 in December came within the normal range at 22, and a CT scan showed a rightovarian cystic area, but nothing suspicious.Since that time, JR has diligently followed her nutritional program, and is in excellent health. HerCA 125 has been within the normal range, the most recent level from 2005 coming in at 7. Sheexcels at a stressful job that requires considerable travel, but nonetheless manages her nutritionalprogram efficiently and effectively. Today, nearly 13 years after she began with me, she has noevidence of cancer, and has been able to avoid the intensive chemotherapy her doctors at JohnsHopkins aggressively pushed so long ago. Her long-term disease free survival to me is certainlyintriguing.In fact the two patients I have discussed with a history of ovarian cancer – AL and JR – bothrefused the chemotherapy that was strongly suggested after the initial surgery documentedextensive disease. We find that patients with a diagnosis of ovarian cancer who have received,before consulting with us, multi-agent chemotherapy tend to have a more difficult course, withmany ups and downs.CASE 4Patient AL: A 10-Year Survivor of OVARIAN CANCERPatient AL, prior to developing cancer, had a long history of neuro-muscular symptoms dating to1979, when she first developed a mass in her left calf, associated with muscle pain, atrophy, andnumbness. In the intervening years, as the symptoms worsened, she consulted numerous physiciansat numerous centers. Though multiple muscle biopsies had all been unrevealing, she wasnonetheless treated empirically and unsuccessfully with a variety of drugs including prednisone. In1985, she sought another evaluation at the Mayo Clinic, where a muscle biopsy confirmedpolymyositis. After she was also diagnosed with motor and sensory neuropathy, type II, AL begananother course of prednisone but with little improvement, followed by six months on Imuran. Thelatter drug did nothing for her disease, but did lead to weight gain, insomnia and anxiety.As her symptoms worsened, AL, who knew of my work from a family member, decided to seek598

treatment with me for her neuromuscular problems. When she first came to my office in 1989, shehad been off all medications for some three years, during which time her symptoms of weakness,nerve pain and numbness continued to progress. When I first saw her, she had no gynecologicalproblems other than the history of a hysterectomy for uterine fibroids.I designed a protocol to treat this patient’s muscle and neurological problems, without the highdoses of enzymes we use against cancer. Subsequently, AL complied well with her program, andwhen I saw her for a return visit in August 1989, she reported her condition that had worsenedwithout respite over the previous 10 years had improved significantly. She described a “20%”overall gain in motor strength and calf thickness, a marker her previous doctors had used to trackher decline. The proximal muscle weakness in both legs had reversed to the point she could standfrom a sitting position for the first time in years. However, on exam I detected a small pelvic massand told her she needed to follow up with a gynecological evaluation upon returning home.Some weeks later, in early fall, an ultrasound revealed a 7 x 8 cm cystic lesion posterior to thebladder. Then in early November 1989, at the Moffitt Cancer Center in Tampa, she underwentexploratory laparotomy and was found to have extensive malignant disease throughout her pelvisand abdomen. Her surgeon proceeded with bilateral oophorectomy, omentectomy, and extensivelymphadenectomy of pelvic, periaortic and precaval lymph nodes. The pathology report describes“Omentum diffusely infiltrated by papillary serous carcinoma” of ovarian origin, as well as tumorin both ovaries that involved both fallopian tubes. Cancer had infiltrated into all 21 of 21 nodesevaluated, and peritoneal washings were positive for “metastatic adenocarcinoma consistent withovarian primary.”After surgery, AL met with an oncologist who strongly recommended intensive chemotherapy, butshe decided to refuse all conventional treatment, instead choosing to begin the cancer version of mytherapy. At that point, I redesigned her regimen to include high doses of pancreatic enzymesthroughout the day.In December 1989 her oncologist wrote a summary note to me, which accompanied the records ofher recent hospitalization. In his letter, he states:“She is diagnosed as having a Stage IIIC Grade I papillary serous cystadenocarcinoma of theovary. I have recommended that she receive chemotherapy. She would be a candidate for GOGProtocol 104 intravenous Cisplatinum and Cyclophosphamide versus intraperitoneal Cisplatinumand Cyclophosphamide. Mrs.---- unfortunately did not wish to pursue the idea of chemotherapy…”She thereafter followed her program diligently for six years. By the mid 1990’s, her muscleweakness began to progress once again, making return trips to New York difficult, though shecontinued on the regimen and we worked together by phone. We last spoke in August of 1999, whenshe wrote after hearing me on the radio. She was 78 at the time, able to walk with a leg brace, andotherwise was doing fine, apparently cancer free nearly 10 years out from her diagnosis ofextensive ovarian malignancy.DeVita reports, regarding ovarian cancer patients such as this:“patients with stage III disease have a 5-year survival rate of approximately 15-20% that isdependent in large part on the volume of disease present in the upper abdomen…”2In this patient’s case, the disease did extend into the upper abdomen at the time of diagnosis.Furthermore, these survival statistics refer to patients treated with aggressive chemotherapy, whichAL refused, choosing to follow only my regimen. Her prolonged disease free survival can only beattributed to her nutritional program.CASE 5Patient JR: A 13-Year Survivor of OVARIAN CANCERPatient JR is a 57 year-old woman whose father developed both rectal and primary liver cancer,and whose mother survived breast cancer before dying of pancreatic cancer. She herself had a599

history of gynecological problems dating back to 1981 when at age 31 she was first diagnosed withbilateral ovarian cysts. Over the years, her gynecologist followed her with sequential ultrasoundsand recommended surgery when she developed persistent severe pelvic pain. JR refused hissuggestion, instead deciding to treat herself with alternative approaches, including several visits tothe Hippocrates Institute, a live-in facility offering a raw vegetarian approach to various diseases.She believed her nutritional interventions did help her overall health, though the cysts did notregress.In March 1993, during a period of extreme personal stress, the patient herself felt that the cysts hadenlarged. An ultrasound at Johns Hopkins Hospital revealed:“…a large approximately 14 X 10 x 12 cm mass in the mid line pelvis….Multiple foci of hyperechogenicityare noted…Therefore, this mass likely arises from the left ovary.“…Within the right ovary, there are two hypoechoic regions and a focus of calcification…Thelargest hypoechoic region measures approximately 1.5 x 1.6 x 1.5 cm….”At that point, her gynecologist insisted she undergo exploratory surgery, but JR instead returned tothe Hippocrates Institute for a several week stay. Despite the aggressive dietary intervention, themass continued to grow.In mid-October 1993, JR returned to her gynecologist, with the large pelvic mass clearly evident.Another ultrasound revealed that the mass had grown considerably since March, now measuring"20 x 22 x 15 cm." The radiology report states “This has moderately increased in size since the lastexamination…A normal right ovary is identified….”JR then proceeded with surgery at Johns Hopkins Hospital after her physician agreed to removeonly the mass and the associated ovary, not the uterus or right ovary. During the procedure, shewas found to have a huge tumor that had penetrated into the recto-sigmoid area of the colon.Though the surgeon did preserve the uterus and right ovary, his resection was quite extensive asdocumented in the Discharge Summary:“The patient …underwent surgery on November ---1993, undergoing an exploratorylaparotomy…resection of ureterosacral tumors, resection of left parametria, omentectomy,resection of rectosigmoid, left common iliac node dissection and para-aortic lymph nodedissection…”The pathology report describes an enormous tumor, “measuring “17 x 12 x 7 cm” consistent with“Adenocarcinoma probably serous,” though the tumor was finally classified as a clear cell subtypeof ovarian adenocarcinoma. The lymph nodes appeared free of cancer, as did the right ovary. Sincethe disease appeared to be largely limited to the left ovarian mass, as big as it was and though thetumor had penetrated the colon, she was assumed to have “localized” stage I cancer.Postoperatively, JR met with an oncologist at Johns Hopkins who strongly recommendedchemotherapy. She initially agreed to the treatment, but after her discharge from Hopkins – withplans to return to start therapy - she then consulted with a second oncologist at George WashingtonUniversity Medical Center, who was less insistent about the need for immediate treatment. JRtherefore decided to refuse conventional approaches, though she did agree to return for routinesurveillance. Note that a CA 125, a blood marker for ovarian cancer, was 16.1 at the time, withinnormal limits.After learning of my therapy, she first came to my office in January 1994 and subsequently followedher nutritional therapy faithfully. When she returned for her first follow-up visit in April 1994, threemonths after she had begun treatment with me, she reported feeling “better than I have in years,”with significant improvement in her energy, stamina and well being. Shortly after that session, sheexperienced mild midcycle bleeding and consulted her local gynecologist, who felt a mass in thepelvis on exam. JR detailed the interaction with her oncologist in a note to me in late April:“I continue to feel great. What is so frustrating, though, is going to the doctor and being toldsomething might be wrong when I am feeling the best I have in years. I think that on some level, Dr----(the oncologist) hopes that something will be wrong so that he can prove to me that my programwill not work.”600

Despite the concern, an ultrasound in May showed no lesions on the ovary, no fibroids, and afollow up exam with her gynecological oncologist was normal. Subsequent CA 125 tests all fellwithin the normal range.JR continued doing well until mid-December 1995, nearly two years after she had started hernutritional program, when she developed sudden onset abdominal pain associated with nausea andvomiting. When the CA 125 came back elevated at 52 (normal less than 36), her oncologistimmediately suggested radiographic studies. Before any testing could be done, her symptomsbecame so severe she went to the local emergency room, where an intestinal obstruction was ruledout. After intravenous hydration, she improved and went home, with a diagnosis of gastroenteritis.A repeat CA 125 in December came within the normal range at 22, and a CT scan showed a rightovarian cystic area, but nothing suspicious.Since that time, JR has diligently followed her nutritional program, and is in excellent health. HerCA 125 has been within the normal range, the most recent level from 2005 coming in at 7. Sheexcels at a stressful job that requires considerable travel, but nonetheless manages her nutritionalprogram efficiently and effectively. Today, nearly 13 years after she began with me, she has noevidence of cancer, and has been able to avoid the intensive chemotherapy her doctors at JohnsHopkins aggressively pushed so long ago. Her long-term disease free survival to me is certainlyintriguing.In fact the two patients I have discussed with a history of ovarian cancer – AL and JR – bothrefused the chemotherapy that was strongly suggested after the initial surgery documentedextensive disease. We find that patients with a diagnosis of ovarian cancer who have received,before consulting with us, multi-agent chemotherapy tend to have a more difficult course, withmany ups and downs.CASE 6Patient IL: A 15-Year Survivor of Non-Hodgkin’s LymphomaPatient IL is a 64 year-old woman from the Southwest who in the fall of 1987 first developed vagueabdominal discomfort. When the pain persisted, in January 1988 her physician referred her for aCT scan, which revealed several large abdominal tumors. In January 1988 she underwentexploratory surgery, hysterectomy and bilateral salpingo-oophorectomy, with resection of twolarge masses attached at the mesentery together measuring 9 x 8 x 8 cms in diameter. Thepathology report describes the lesions as consistent with diffuse mixed lymphoma, mixed small andlarge cleaved cell type, a very aggressive form of the disease.IL then completed six months of chemotherapy with MACOP-B, an intensive regimen consisting offive different chemotherapy drugs and the steroid prednisone. Repeat CT scans in August 1988, atthe completion of treatment, were negative and her doctors assumed her to be in remission.Subsequent scans were clear until May of 1991 when a CT picked up two nodules in the lungs, thelargest in the lingula measuring 1.6 cm, the smaller in the left lower lobe measuring 0.6 cm. Inaddition, the report describes “small periaortic lymphadenopathy at the level of the kidneys” whichhad been noted on prior scans. A chest CT in July 1991 revealed a 2.5 by 2 cm. mass in the lefthilar area, an abnormality of the lingula, and a left lower lobe mass:“1. Left hilar mass and posterior left lower lobe nodule.2. Progressing mass and associated atelectasis or infiltrate in the lingula.”Although her doctors discussed resuming chemotherapy, IL as she says had “had enough.” Afterlearning of our work from a friend, she then decided to pursue our program.When I first saw IL in my office in September 1991, she generally felt well, and thereafter proved tobe a very compliant patient. Six months after beginning her regimen, in March 1992, a repeat CTscan of the chest demonstrated a small pleural based density associated with the anterior leftcardiac margin, approximately 1 by 1.5 cm in size, that had significantly regressed since the scans601

of 1991. And, the additional lesions previously described were not evident. An abdominal CT scanrevealed “slightly prominent nodes on the para-aortic area measuring up to 1 cm in diameter” butno other worrisome lesions.In September 1992, after she had been on her program a full year, CT studies of the abdomen andpelvis were clear, but the chest CT showed a “3.5cm x 2 cm density in the left mid lung and lowerlung field which, according to the previous dictation, has increased in size significantly and,therefore, must be considered an active lesion…”When I discussed the findings with IL she seemed determined to continue with her nutritionalprogram only, expressing no interest in pursuing any other treatment. After I made someadjustments in her protocol, she decided to forgo future CT scan studies. She said not only did theycreate enormous anxiety, but she had no intention of changing treatment whatever the tests showed.Over the next decade, IL continued her regimen, with excellent compliance. She generally enjoyedgood health, despite some ongoing problems I relate to her earlier chemotherapy, such as apersistent irregular heart rhythm and episodic respiratory symptoms, including shortness of breathwith exertion. One of the drugs in the MACOP-B regimen, daunorubicin, has long been associatedwith heart damage in a significant number of patients, and bleomycin often provokes pulmonaryfibrosis, sometimes years after treatment. In January 2004, she did undergo both cardiac andpulmonary evaluations which revealed no significant underlying disease. A chest x-ray at that time– her first radiographic study since the CT scan of 1992 – showed a “small left apicalpneumothorax. Chest x-ray is otherwise radiographically normal.” The previously describedmasses seen on CT were gone, and I relate the area of collapse to bleomycin use years earlier.IL today, now on her nutritional regimen over 15 years, continues in good health with apparenttotal resolution of her once aggressive disease. She enjoys her life, is grateful that she has lived tosee her children grow, marry, and raise their own children.The diffuse and diffuse mixed types represent particularly aggressive forms of lymphoma thatfrequently come back after even the most aggressive of chemotherapy regimens. Harrison’s reportsthat the disease recurs in nearly 50% of treated patients with this diagnosis, and of these, fewerthan 10% will respond to additional chemotherapy.2 Certainly this patient faced a grim future,once the CT scan studies in 1991 confirmed new disease.CASE 7Patient LL: An 11-Year Survivor of Non-Hodgkin’s LymphomaPatient LL is a 54 year-old man who previously had been in good health when in July 1995 hedeveloped severe chronic indigestion, abdominal pain and constipation. His symptoms did notimprove despite a variety of medications and dietary changes. After he developed swelling of theleft testicle in September 1995, he was referred to a urologist who ordered a CT scan of theabdomen and pelvis. The tests, done in October 1995, revealed:“extensive retroperitoneal adenopathy including retrocrural, periaortic, mesenteric and paracavaladenopathy. The nodes measure up to 5 cm in diameter individually and in conglomerate measurenearly 15 cm in transverse diameter and 8-10 cm AP…”An excisional biopsy of an enlarged cervical lymph node revealed nodular non-Hodgkin’slymphoma (mixed lymphocytic/histiocytic type).After the diagnosis, he received no orthodox treatment, instead choosing to follow our regimen. Hewas first seen by Dr. Isaacs in November 1995, and as he subsequently followed his nutritionalregimen, he experienced a gradual improvement in his overall health. For a number of years, he602

avoided all testing until May 2001, when a CT of the abdomen and pelvis showed “Resolution ofpreviously noted adenopathy. The study at this time is essentially unremarkable.”This patient’s course has been very simple and straightforward. He was diagnosed initially withextensive stage IV moderately aggressive histology disease, refused all standard treatments,followed his nutritional program appropriately, and enjoyed complete regression of his cancer andlong term survival. He is now 11 years from diagnosis, still in good health.CASE 8Patient DC: a 12-Year Survivor of Non-Hodgkin’s LymphomaPatient DC is a 63-year old woman who 1992 first noticed a robin’s egg sized lesion in the rightlower abdominal wall. She consulted her primary care physician, who suspecting a benign lipoma,suggested no testing be done.Over the next three years, as the nodule remained stable, DC continued in good health, with nosymptoms other than a single episode of night sweats and occasional pruritis. At one point, whenshe was found to be mildly anemic, her physician prescribed iron supplements.In the fall of 1994, her gynecologist, after a routine exam, suggested a diagnostic evaluation of theabdominal wall lesion. A CT scan revealed a solid mass on the right lower abdominal wall, but noother abnormalities. Then in November 1994 the nodule was excised and described in the pathologyreport as 4.5 x 4.0 x 1.8 cm, consistent with “malignant lymphoma, diffuse, small lymphocytic type(well differentiated lymphocytic lymphoma) of abdominal wall.”After referral to an oncologist, a subsequent bone marrow biopsy was clear, but she was againfound to be anemic, with a hemoglobin of 11.8. In January 1995, she underwent repeat CT studieswhich revealed new nodularity in the left pelvis side wall and in the cul-de-sac, thought most likelyrepresenting new pelvic malignant lymphadenopathy.The hospital Tumor Board then discussed the case and recommended a conservative approachinitially, with regular follow up CT scans to assess disease progression. A bone scan in October1995 was negative. CT scans in January 1996 demonstrated two lesions within the right lobe of theliver, the largest measuring 2.0 cm in diameter, that were thought to have been present on the priorexams. In addition, the radiologist noted “redemonstration of a large, inhomogeneous centralpelvic mass with prominence in both adnexal regions,” as well as “thickening of and someinhomogeneity to the appearance of the left piriformis muscle when compared to the right…”Though her physicians still recommended a conservative approach, DC began investigatingalternative approaches, learned of our work, and in April 1996 first consulted with me. When firstseen, she reported no significant symptoms.DC proved to be a determined and compliant patient, whom I don’t think has missed a dose ofsupplements in the 10.5 years she has been my patient. Periodically, I have recommended CT scans,which generally have showed no change in the pelvis lesions. Her most recent scan in May 2006revealed the same “two small low density lesions within the liver…unchanged and measuring up to1 cm.” In terms of the pelvic mass, the report states:“There is large lymphadenopathy contiguous with the left piriformis muscle, unchanged in sizemeasuring 9 cm in length x 4.5 cm. in width. Again noted are areas of linear enhancement… Thereis a 4.5 cm. in length x 2.7 cm in width soft tissue mass in the proximal aspect of the left thigh whichis slightly decreased in size…”The diffuse forms are among the more aggressive of the lymphomas, usually calling for aggressivechemotherapy. In this particular case, the consulting oncologists opted for a conservativeapproach, holding chemotherapy in reserve for a time the disease would inevitably progress.However, during the 10.5 years DC has followed her nutritional program, the disease has remainedgenerally stable, with some recent regression.In many of our patients, regardless of the cancer type, tumors resolve, as in the case of Patient LLabove. At other times, as with Patient DC, the tumors can remain stabilized for years. I have never603

een able to offer a reasonable scientific explanation why this should be so, why sometimes largetumors regress remarkably, at other times in other patients the tumors don’t grow or spread, butdon’t disappear either.CASE 9Patient DK: A 7-Year Survivor of Non-Hodgkin’s LymphomaPatient DK is a 48 year-old woman who prior to developing cancer had a long history of lowerback pain treated conservatively with acupuncture, massage, yoga and swimming, modalities whichoffered some relief. In 1993, when her pain worsened, she underwent laminectomy of the L2-L3-disc. Postoperatively her back pain, although reduced, did not resolve completely. In November1993 she underwent an MRI of the lumbar spine which showed L5-S1 disc bulging, and somedegeneration in several other lumbar discs. In addition, the radiologist noted left para-aorticadenopathy. The patient then consulted with an oncologist at New York Hospital-Cornell, whorecommended a CT scan, which, in December 1993, confirmed enlarged left para-aortic lymphnodes, though the patient was not informed of the findings.Since she didn’t hear from her oncologist, DK assumed “everything must be fine.” Thereafter, shedid well until mid 1998, when she developed gradually worsening fatigue, associated with recurrentupper respiratory infections. In the fall of 1998, she consulted her primary care physician, whodetected a right parotid mass as well as cervical lymphadenopathy. Initially, her internist was notconcerned, assuming the enlarged nodes related to her most recent bout of the “flu.” But, when theadenopathy failed to regress, DK consulted the oncologist she had seen years earlier at New YorkHospital. The physician referred her for an MRI of the neck in March 1999, which revealed two 1cm lesions in the right parotid gland as well as enlarged upper cervical nodes. A CT scan of thechest in April 1999 demonstrated abnormal hilar nodes, the largest measuring 17x12 mm. CT scanof the abdomen revealed:“a chain of enlarged nodes (2-3 cm…) in the left paraaortic region from the level of left renal hilarvessels….extending into the proximal left common iliac chain. Largest node at L3 level measures3x2 cm.”A biopsy of the parotid lesion then confirmed malignancy “consistent with a B cell (non-Hodgkin’s)lymphoma.” A bone marrow biopsy was clear.With the diagnosis established, the oncologist recommended a “watch and wait” approach, holdingoff chemotherapy for a time when the disease worsened. DK then sought a second opinion atMemorial Sloan-Kettering, where the slides were reviewed and the diagnosis confirmed. TheMemorial oncologist suggested two options, the conservative, no immediate treatment approach, ora course of aggressive chemotherapy.DK then met with a third oncologist, a lymphoma specialist at New York Hospital, whorecommended no treatment initially, but that the scans be repeated in October 1999 to assessdisease status.DK, with a long interest in alternative medicine, knew about my work and decided to consult withme. When we first met in June 1999, she had obvious cervical adenopathy. Thereafter, she followedher nutritional regimen initially with great determination and good compliance. Follow-up CTscans in March 2000, when she had been on her therapy only nine months, showed substantialimprovement. The report for the CT scan of the neck states:“Appearance of regression in intraparotid nodes on the right.”The CT of the chest showed:“Interval complete regression in adenopathy. There is no evidence for active lymphoma.”The CT scan of the abdomen indicated:“Interval virtually complete regression in adenopathy. There is no evidence of active lymphoma.”604

The CT scan of the pelvis revealed:“Interval complete regression in adenopathy. There is no evidence for active lymphoma.”As DK continued her nutritional therapy, she experienced a gradual improvement in her overallenergy and well being. When in mid 2001 she went through a period of severe personal andprofessional stress, her compliance with therapy fell off somewhat. On exam, I could see clearlythat the neck disease had worsened. CT scans in October 2001, 19 months after the documenteddisease regression, showed little change in the chest, abdomen and pelvis, but increased“pathological adenopathy in the right neck.” After I lectured her about the need for diligentcompliance, for a time she seemed more determined, but the stress continued unabated and hercompliance varied. At times, she might have been doing 50% of the therapy and a CT of the neckscan in January 2002 revealed continued progression in the adenopathy. The report of theabdominal and pelvic CT scans describes:“Mixed behavior of nodes with periaortic nodes slightly less prominent and hyperplastic nodes inthe small bowel mesentery more prominent…Interval appearance of focal splenic lesions…”This time, we talked about the need for complete compliance with all aspects of the regimen,regardless of the difficulties in her life. Fortunately, her oncologist did not insist that chemotherapybegin at once, since she had previously responded so well to my treatment. DK renewed herdedication to the regimen, with repeat CT scans in January 2003 confirming the benefit. The neckCT showed “Substantial decrease in the extensive adenopathy in the right neck.” The abdominalCT scan indicated:“Interval disappearance of small splenic lesions and slight decrease in sight of spleen…Nopathologic adenopathy is seen in the abdomen or pelvis.”Thereafter, she followed the therapy as prescribed, and continued doing well. A neck CT in March2004 revealed:“Complete regression in pathologic and borderline sized neck nodes.”The CT scans of the abdomen and pelvis were completely clear, as the official report describes:“There is no other interval change and no evidence for active lymphoma in abdomen and pelvis.”Unfortunately, her stress level subsequently increased markedly and after a long-term relationshipdissolved, for a number of months she went off her program completely. Her energy worsened, hersleep became disturbed. Predictably, a CT scan of the neck in February 2006 showed “New andprogressive adenopathy along the right jugular chain and posterior triangle.” CT scans of thechest, abdomen and pelvis showed recurrent disease.She is now again on her program, determined once again to get well, and clinically the enlargedneck nodes are regressing. She feels stronger, more energetic, more positive.Though DK has not followed a straight and narrow path, her course does say much about ourtreatment. When she complied fully, her extensive disease regressed completely. When hercompliance fell off, the disease recurred, then again regressed when she resumed her full protocol.Over the years, her disease status has correlated precisely with her compliance.Patients, including mine, do not lead perfect lives. Often, they must deal with many life-stressesabove and beyond their cancer, stresses which can influence mood, motivation and dedication totreatment. But DK, despite her lapses, has generally done very well over the past 7.5 years on hernutritional program, has successfully avoided all chemotherapy and radiation, and currently feelsstrong and healthy.CASE 10Patient LR: An 11.5-Year Survivor of Non-Hodgkin’s LymphomaPatient LR is a 60-year old woman with a history of an insulinoma, diagnosed in 1977, treatedeffectively with partial pancreatectomy. Her doctors recommended neither chemotherapy norradiation after surgery, and thereafter she did well until December 1993 when she first noticed605

swollen lymph nodes under her chin. When the swelling did not regress, in January 1994 sheconsulted her internist who suspected the problem related to infected gums. She was referred to aperiodontist who performed gum debridement, but when the lymph nodes enlarged further inFebruary 1994, she returned to her internist who prescribed penicillin, without effect. About thattime, she first developed significant night sweats that persisted for a week, as well as abdominalpain. Her physician referred her for an ultrasound, which revealed a large 7 cm cystic mass in thetail of the pancreas which a CT scan confirmed. The radiologist thought the lesion consistent with abenign pseudocyst, and when a needle biopsy proved inconclusive, her doctors recommended nofurther testing.Because of the persistent enlarged lymph nodes in her jaw, in April 1994 LR consulted an ENTspecialist who did not initially suggest biopsy, but in June, LR noted new inguinal adenopathy. Atthis point, the patient’s internist prescribed a course of Cipro for what was now thought to be catscratch fever, which antigen testing did confirm. Although the nodularity persisted even after shecompleted a course of Rifampin, her primary physician remained unconcerned. When theadenopathy progressed throughout September, LR again returned to her doctor, who again told her“not to worry.” In one of the physician’s notes from the time, he described her as “borderlinehysterical.”Finally, LR decided to consult the surgeon who years earlier had resected the insulinoma. InOctober 1994, this physician – somewhat more disturbed by the adenopathy - removed a nodalmass from the posterior neck-right shoulder junction that proved to be “Follicular lymphoma,predominantly small cleaved cell type (nodular poorly differentiated lymphoma).” Experts at thePathology Laboratory of the National Institutes of Health reviewed the slides and confirmed thediagnosis.In late October a CT scan of the chest revealed “marked lymphadenopathy in multiple mediastinal,left hila (sic), retrocrural and axillary areas…consistent with the clinical diagnosis of lymphoma.”An abdominal CT scan showed: “There is extensive adenopathy in the abdomen and pelvis, withlymph nodes ranging up to 3x4.4 cm and 4.6x6 cm.” A gallium scan documented extensive uptakein the mediastinum and abdomen.Shortly thereafter, in November 1994, LR began chemotherapy with CHOP, a standard lymphomaprotocol, at a local academic medical center. In late December, after she had completed threecycles of the proposed course, CT scans demonstrated improvement, but not resolution, in both thechest and abdomen, reported as: “Interval decrease in size of adenopathy within the rightparatracheal group, subcarina, left axillary and retrocrural nodes…” In the abdomen theradiologist noted “lymphadenopathy has decreased by more than 50% since exam of 10---94consistent with partial response to chemotherapy.”In March 1995, after LR had completed the full six cycles of the regimen, CT scans indicated somecontinued response to therapy, but definitely not complete remission. The chest CT showed “Slightcontinued improvement in right paratracheal lymph node disease with stability of diseaseelsewhere…” The abdominal CT revealed:“When compared to previous examination, the lymphadenopathy appears stable except for anapparent worsening in the region of the root of the mesentery…”With chemotherapy completed but her disease not in remission, LR began investigating alternativeapproaches, learned of my work, and first consulted with me in April 1995. Her exam wasunrevealing, except for multiple palpable right cervical lymph nodes.She thereafter began her program with great determination. In November 1995, restaging with CTscans of the chest, abdomen and pelvis confirmed significant improvement:“No significant mediastinal or hilar adenopathy is identified. The lungs are clear without evidencefor masses…Retrocrural adenopathy seen on the previous examination is now not identified. Smallperiaortic and mesenteric lymph nodes are identified which have decreased in size since theprevious examination…”CT studies in February 1996 showed no evidence of recurrent disease, as did subsequent scans606

over a period of two years. Throughout this time, she was noted to have, on exam, several smallright cervical nodes. In May 1998, the oncologist who followed her along with me suggested abiopsy of one of the neck nodes, which did reveal residual lymphoma described as “Follicular,mixed small cleaved and large cell type…” At that point, the oncologist recommended, along withmy therapy, a course of Rituxan, a monoclonal antibody treatment designed specifically to attacklymphoma cells. I felt the treatment unnecessary since she had already responded so well to myregimen, but the oncologist was persuasive and I did not push the case. So, in the spring and earlysummer, she completed four cycles of the drug, which she tolerated with minimal difficulties. Onexam, her cervical nodes regressed completely. CT scan studies of the chest, abdomen and pelvis inSeptember 1998 reported “No evidence of recurrence.” CT scan of the neck showed “Multiplesmall subcentimeter lymph nodes bilaterally which have decreased in size and number since theprevious study.”Since 1998, LR has done exceptionally well, now 12 years from her original diagnosis of stage IVlymphoma, and 11.5 years from her first visit with me. She has enjoyed generally excellent healthwith no recurrence of her once widespread disease. The most recent PET/CT scan in April 2006documented:“There is no PET/CT scan evidence of recurrent or metastatic disease.”Her course is unusual, both in terms of the long-term survival and the near total resolution of thedisease as documented by CT scans after only six months on her nutritional therapy. In 1998,before she completed a course of Rituxan, scans of the chest, abdomen and pelvis had been clear. Isuspect her neck nodes eventually would have resolved without Rituxan. Studies do show that 35-50% of patients with follicular lymphoma that relapse after chemotherapy will have some responseto the drug, though the duration of effect is variable with few long-term remissions.2 In any event,in this case the disease had nearly completely resolved before her oncologist urged in 1998 sheproceed with Rituxan, at the time a fairly new, and highly promoted, drug.CASE 11Patient FV: A 3-Year Survivor of Lung CancerPatient FV is a 63-year old man with a history of myasthenia gravis diagnosed in 1993, whichforced him to retire from his high stress profession. Since then, his myasthenia has waxed andwaned, with exacerbations treated with Tensilon.In June 2003, while playing tennis, he developed significant shortness of breath. At a localemergency room, a chest x-ray showed several pleural-based densities in the left lung and a CTscan revealed several nodular lesions in the left chest pleura up to 2 cm in diameter. Posteriorpleural thickening was also noted, thought consistent with mesothelioma. When his symptomsworsened, a second chest x-ray documented a left pleural effusion, subsequently treated with chesttube placement and drainage. After recovering from the acute episode, a second CT scan in Julydemonstrated a collapsed left lung, a persistent left pleural effusion and numerous large tumors.The official report states: “the largest pleura bases (sic) mass in the left upper lobe laterallymeasures 2.976 cm…The largest mass in the left lower lobe posteriorly measures 5.39 cm…Thereare at least 18 pleural based masses present on the left.”FV then underwent bronchoscopy, left video assisted thoracotomy with pleural biopsies, andpleurodesis. The initial pathology report of the biopsy specimen suggested most likelymesothelioma, but a review at The Armed Forces Institute of Pathology confirmed notmesothelioma, but, as the note describes:607

“Pleura, left, biopsy: Metastatic papillary adenocarcinoma, of pulmonary origin.”His local doctors also sent the pathology slides to Brigham and Woman’s Hospital in Boston, aresearch center for mesothelioma, where, in July the tumor was thought most likely a papillaryadenocarcinoma of the lung, staged at IIIB.In late July 2003 FV decided to consult with Dr. David Sugarbaker, a thoracic surgeon and expertin pleural lesions at Brigham and Women’s. At Brigham, CT scans of the abdomen and pelvis wereclear. A total body PET scan confirmed the extensive left pleural lesions but showed no evidence ofdistant metastatic disease. Since the disease seemed localized to the chest, Dr. Sugarbakerproposed the tumor be treated as if it were a pleural lesion like a mesothelioma with extensivesurgery, including removal of the entire left lung, the pericardium and the left side of thediaphragm.This debilitating approach seemed excessive, so FV, upon returning home, consulted with anoncologist in the Washington DC area who believed the situation should be approached initiallynot with surgery but instead with an aggressive chemotherapy regimen. If the tumors regressedsignificantly, a less aggressive procedure might be feasible. The oncologist also consulted withthree additional thoracic surgeons, including one within the NIH system, who felt the surgicalapproach suggested in Boston overly aggressive, and that the tumor should be treated as a primarylung cancer, not as a pleural tumor like mesothelioma. All believed chemotherapy should be theinitial therapy of choice.FV then traveled to New York for a consultation with the Chief of Thoracic Surgery at MemorialSloan-Kettering, who concurred that the disease appeared to be lung cancer that had spread to thepleura, not the other way around. She recommended chemotherapy as the first line treatment,perhaps followed by surgery.With the debate resolved, in September 2002 FV began a four-cycle course of Gemzar andcarboplatin. After he completed his last treatment in November 2002, a CT scan revealed someslight worsening in the largest tumor, despite the chemotherapy:“The cystic structure in the posterior left upper lung…measuring 4.8 x 6 cm, compared to priormeasurements of 4.5 and 5.9 cm. The pleural based lateral left upper lung lesions are alsoessentially unchanged, measuring 2.6 and 2.9 cm, compared to prior measurements of 2.8 and 2.9.The rest of the pleural-based masses and left basilar pulmonary nodules are unchanged…”Since the disease had progressed, even if slightly, FV began investigating alternative approaches,learned of our work and consulted with me in mid December 2003. At the time, he generally feltwell and seemed to have recovered from chemotherapy quickly. Thereafter, he began his nutritionalregimen with great dedication and superb compliance. When I saw him for a return office visitthree months later, in April 2004, he reported feeling “great.” Two months later, in June 2004,PET/CT scan testing confirmed improvement in his disease, as he followed only his nutritionalregimen. The CT describes:“CT-CHEST: Numerous pleural-based masses, and small ones adjacent to the pericardial surfaceare present…Most of these lesions appear marginally smaller than they previously did (note:compared to the November 2003 CT scan), by a few millimeters. The largest lesion, locatedposteromedially in the mid-chest, again appears largely necrotic…“Soft tissue abnormality in the left upper quadrant of the abdomen, anterior to the splenic flexure,appear slightly smaller in overall bulk as compared to the prior study…”Note that the prior radiology reports had not described the lesion in the abdomen, a metastaticfocus which would confirm stage IV, not stage III disease. Apparently the lesion had been evidenton prior scans, but not described in the official report.The overall summary of the June PET/CT states:“IMPRESSION: PET scans shows numerous pleural-based pathologic foci in the left hemithorax,consistent with numerous foci of metastatic neoplasm. A lesion at the anterior aspect of the leftupper quadrant of the abdomen, or immediately adjacent diaphragmatic surface is present….“CT examination of the chest shows minimal decrease in the overall size of the numerous pleural-608

ased masses in the left hemithorax, and in the region located either in the left upper quadrant ofthe abdomen…”So, while the PET confirmed residual active cancer, the CT scan indicated universal, though slight,reduction in the many tumors with advancing necrosis in the largest remaining tumor.Since that time, FV has continued his nutrition regimen vigorously, and has done extremely well.He has declined all invitations for follow up CT and PET/CT scanning, stating he wouldn’t changehis treatment regardless of what the tests show. So, while we don’t have clear evidence ofadditional tumor regression, his continued survival, now at three years since he began hisnutritional regimen, and his excellent general health speak for themselves.His course has had only one complication. In the spring of 2006, FV felt well enough to take a tripto Europe with his wife. Upon arriving abroad, he developed severe headaches requiringhospitalization. After CT scans and MRI’s of the head showed nothing, he was eventually diagnosedwith a cerebrospinal fluid leak. He returned to the United States, the problem eventually resolvedand once again, FV is back to his usual state of well being.In analyzing this case, it’s important to keep in mind that although the disease was originallyclassified as stage IIIB lung cancer, the PET/CT scans in June 2004 clearly showed an abdominallesion that would indicate stage IV metastatic disease. Though evident on prior scans, this lesionwas not mentioned in the formal reports. Also, a CT scan done weeks after FV completed his fourcycles of aggressive chemotherapy showed no reduction in any of the tumors, and someenlargement. Only after he had followed nutritional program some six months did the PET/CTscans document regression in all tumors, and the appearance of significant necrosis in the largest.For patients with stage IV non-small cell lung cancer, studies show chemotherapy improvesaverage survival by about one month over supportive care only. Even with the newest mostaggressive chemotherapy regimens, median survival is still only 9-10 months, with, depending onthe regimen, a mere 25-40% of patients living 1 year.3 Virtually none survive 5 years. FV’s 3-yearsurvival and excellent health are even at this point extraordinary.CASE 12Patient RZ: Lost to Follow-up After Tumor Regression of Lung CancerPatient RZ was one of the first patients I treated with a diagnosis of metastatic lung cancer after Iopened my practice in late 1987. He had smoked cigarettes heavily for 28 years, before quittingsome 15 years prior to developing cancer. Otherwise his health had generally been good when inearly 1987, he first developed persistent chest pain and cough. When his symptoms did not resolve,he consulted his local physician. After an x-ray revealed a right lung mass, in March 1987 heunderwent bronchoscopy with biopsy confirming adenocarcinoma of the lung. A CT showed twotumors, one in the right apex, the second in the right hilum, though the left lung appeared clear.Since the disease appeared limited to the right lung, surgery was immediately suggested. RZinitially refused all conventional intervention but when his symptoms worsened he agreed toproceed with surgery. In July 1987 he underwent a right pneumonectomy, with the pathology reportdescribing a 2.5 cm lesion, consistent with poorly differentiated adenocarcinoma, extensivelyinvading the hilar lymph nodes. He was staged at III, and proceeded postoperatively with a courseof radiation to the chest totaling 4500 rads.RZ subsequently did well until September 1988, when he developed persistent headaches andolfactory hallucinations described as putrid foul smells. A CT scan of the head in October 1988revealed multiple tumors located in the temporal, right frontal and left occipital areas withassociated edema. His doctor prescribed the steroid Decadron to reduce the cerebral swelling butthe symptoms did not improve. In early November 1988 he proceeded with a ten-day course of609

adiation to the head, ultimately receiving a total of 3000 rads, with some improvement in hissymptoms. In December 1988, a month after completing radiation, a CT scan of the head revealedthe situation had worsened despite treatment:“Multiple, bilateral intracerebral ring-enhancing lesions, consistent with metastases. In additionthere appears to be an early left cerebellar hemisphere lesion. Many of these were noted on Oct---1988. However, several new small areas of abnormality are identified on the present exam, notpreviously seen…”At this point, with his disease progressing, RZ, who already had been investigating alternativeapproaches to cancer, came to New York for a consultation with me. He reported severeneurological symptoms, including headaches, that had recently recurred despite Decadron. Hethereafter began his nutritional program with initial great enthusiasm, and in January 1989, afterhe had completed but a month on his nutritional program, a CT scan showed significantimprovement:“When compared to the last previous exam of 12—88, there has been diminution both in the sizeand number of the visualized intracranial lesions. No new areas of abnormality are seen.”According to his oncologist’s notes, a bone scan in March 1989 showed clearing of previous notedbone lesions, though I do not have the actual radiology report.At that point, RZ was symptom-free and strong enough to return to his stressful job. Unfortunately,he felt so well he became careless with his supplement regimen and diet, and by April 1989 was byhis own admission less than 50% compliant with his overall protocol. Not surprisingly, after hisneurological symptoms returned with a vengeance, a CT scan in May 1989 revealed worseningdisease:“Increased intracranial edema and size of previously reported intracranial metastases whencompared to 3---89.”After a discussion with me about the need for perfect compliance, RZ resumedhis full program as prescribed. His symptoms rapidly improved and a CT scan in July 1989demonstrated reduction in all his brain tumors:“The three metastatic lesions on the 5---89 CT have decreased in size. No new metastatic lesionsare seen….”With the return of his good health, RZ again became careless with his program. I last saw him inSeptember 1989, nine months since our first session, when after several weeks of poor compliancehis neurological symptoms had returned. Thereafter, he was lost to follow-up. He had no familythat I knew of, and despite my efforts, I could never learn what happened to himIn this case, the patient’s disease, before he had consulted with me, had progressed despiteintensive radiation to the brain. After he began his nutritional program the brain (and apparentlythe bone) lesions regressed, only to worsen when compliance fell off. When RZ became moreadherent to the prescribed regimen, the brain tumors again improved. Ultimately, he lacked thededication and discipline to stick to the program as required.DeVita reports a median survival of 15-18 weeks for patients with multiple metastatic brain lesionsfrom non-small cell lung cancer treated with intensive radiation.4 So, despite his complianceproblems, this patient’s 36+ weeks of survival beat the odds.And, again despite his lapses, I thought this patient of interest since he remains one of the few Ihave ever treated with brain metastases from a primary lung neoplasm. Though in recent yearsoccasional patients in this situation have contacted our office seeking information about ourtherapy, most are so far into the terminal stages of their illness we can’t justify trying to treat them.For better or worse, in this age of aggressive oncology, patients facing this diagnosis invariably getshunted frantically and immediately into multi agent chemotherapy and radiation. Only aftermonths of futile treatment, when the disease explodes and the patient weakens, do they beginlooking into alternative options. By then, it is too late. I believe we could help many diagnosed withthis terrible condition if, like RZ, they came earlier in their course, but over the last decade this hassimply not been the case. And we do not accept patients for treatment whom we believe we can’thelp.610

CASE 13Patient SV: A 5.5-Year Survivor of Lung CancerPatient SV is a 44-year old woman who had been in good health when in 1998, she first noticed theneed to repeatedly clear her throat, a symptom she attributed to persistent postnasal drip. By 1999,she had developed a mild non-productive cough associated with a gradual decline in energy,attributed to the demands of tending to her new baby.During 1998 and 1999, SV repeatedly consulted her primary care physician because of ongoingrespiratory symptoms, but she was reassured she had nothing more serious than a recurrent viralsyndrome that warranted no further testing. When the cough and fatigue persisted, she wasultimately referred to an allergist who thought the symptoms were unrelated to allergies. However,no chest x-ray was suggested.The cough and associated problems continued into 2000. At one point in 2000 during a family visit,after hearing the cough, the patient’s sister, a medical professional, insisted a chest x-ray and TBtesting be done. Subsequently, when a TB skin test was negative, SV chose not to follow up with thechest x-ray. A month later, in October 2000, SV developed a significantly worsening coughassociated with a high fever and severe fatigue. She visited her doctor who after an examannounced she once again had a viral infection. When, at end of November 2000, the coughworsened, she requested an x-ray, which her doctor told her showed pneumonia. When thesymptoms did not improve after a second course of antibiotics, a repeat chest x-ray revealed apersistent left lung infiltrate. A CT at that point then showed a large lesion in the left lower lungconsistent with primary lung cancer.SV was referred to a pulmonologist for bronchoscopy and biopsy, which confirmedadenocarcinoma of the lung. With the diagnosis finally made, the patient met with a localoncologist who ordered a full metastatic work-up. A CT scan of the abdomen and pelvis showed aporta hepatis mass that was considered insignificant. In January 2001 SV decided to consult withan oncologist and lung cancer specialist at the Mary Hitchcock Medical Center in New Hampshire.At Hitchcock, after a PET scan revealed only the large lung tumor, with no evidence of metastaticdisease, the physician recommended surgery for resection of the lesion as soon as possible.In January 2001 SV then met with the Chief of Thoracic Surgery at Memorial Sloan-Kettering inNew York. Repeat bronchoscopy at Memorial with transbronchial biopsy confirmed moderatelydifferentiated mucin secreting adenocarcinoma. Repeat PET scan showed a 5.5 cm lesion in the leftlung as well as a 1 cm secondary satellite lesion, but CT scans of the head, abdomen and pelviswere clear. Subsequently, in February 2001 at Memorial, SV underwent left lower lobectomy withthe pathology report describing a tumor 6.2 cm in diameter, consistent with moderatelydifferentiated mucinous adenocarcinoma. Tumor had invaded three of eight lymph nodes evaluated,a very dire prognostic indicator.According to the patient, the Memorial surgeon warned that neither chemotherapy nor radiationwould be very helpful long term and should be held in reserve until the disease recurred, as it mostlikely soon would. SV decided she nonetheless wished to meet with an oncologist, so she consultedat Memorial with a physician pursuing a vaccine research study designed for patients with stage IIIlung cancer. At the same time, she began investigating our work, which a friend had discussed withher. The same day she first consulted with me in March 2001 she also visited Memorial Sloan-Kettering to discuss both chemotherapy and the vaccine trial. The physician’s note from that dayclearly expresses the poor prognosis SV faced:“I had a lengthy discussion with the patient and her husband regarding the situation. The patientalready understands that because of her stage, she is at risk for recurrence in the future. Wediscussed in detail the role of adjuvant chemotherapy and radiation therapy. In one meta-analysispublished in 1995, cisplatin based chemotherapy improved the rate of survival by 5% after five611

years. Radiation typically has been described as improving local control without improvement insurvival due to the risk of systemic metastases. One recent trial published in the New EnglandJournal indicated that the addition of chemotherapy with etoposide and cisplatin to adjuvantradiation did not improve survival.”In the same note, though the oncologist clearly admits that radiation and intensive chemotherapyessentially do little, two sentences later he nonetheless recommends the patient be aggressivelytreated anyway!“For this patient, who is quite young, I would probably favor aggressive treatment, providing herwith some adjuvant chemotherapy with a cisplatin-based regimen…In addition, I also discussedwith her clinical trials...”The vaccine trial, offered as an option to aggressive chemotherapy, turned out to be a preliminarypilot study. Then, after her consultation with me and the Sloan-Kettering physician, SV met with herlocal oncologist, who told her that even with aggressive chemotherapy and radiation, only one infive patients with her specific diagnosis and stage lived beyond a “couple years.”Since little data favored any of the orthodox treatments, SV decided to forgo all conventionalapproaches and begin our nutritional regimen. When we met for our second session some dayslater, she handed me a copy of the consent form for the Memorial Sloan-Kettering clinical study. Ifound it informative in that the researchers clearly discuss the aggressive nature of lung cancer,and its notorious resistance to standard approaches:“Non-small cell lung cancer is a difficult disease to treat. Even after curative surgery, there is ahigh likelihood of the cancer returning. Chemotherapy and radiation are sometimes given aftersurgery to decrease the chance that the cancer will come back; however it is unclear whether thisreally helps. In this study, we are trying to develop a different approach to treat patents with nonsmallcell lung cancer after surgery. We are testing a new vaccine designed to boost your immunesystem against your cancer…”SV then began my therapy with great determination and great dedication. A follow up CT scan fromFebruary 2003 did reveal a 2-3 mm nodule in the periphery of the right lung. A follow up scan inSeptember 2003 showed that ”The nodule in the periphery of the right lung posteriorly….remainsunchanged and stable.” Repeat CT scans in August 2004 reported “A stable 2-3 mm pulmonarynodule is seen in the right lower lobe. No new nodules are seen…” Her most recent scans inOctober 2005 were completely clear.Today, more than 5.5 years first beginning her nutritional therapy, SV remains compliant and ingood health with no evidence of recurrent disease. She continues to follow up periodically with herlocal oncologist, who seems very supportive of the road she has taken.CASE 14Patient DQ: a 15-Year Survivor of Renal Cell CarcinomaPatient DQ is a 82 year-old man who had past history pertinent for celiac disease, gout andchronic borderline anemia. In October of 1990 his primary physician noted an abdominal massduring a routine yearly physical examination. Subsequent MRI and CT scan studies revealed a 14cm tumor in the left kidney, with no evidence of metastases. Chest X-ray and bone scan were bothclear, and in late October 1990 DQ underwent exploratory laparotomy and left nephrectomy.Pathology studies confirmed renal cell carcinoma, with 1/1 adjacent nodes positive for invasivecancer.DQ was then referred to a major New York medical center for additional evaluation and treatment.There, in December 1990 he agreed to enter a clinical trial testing alpha-interferon, an immunestimulant, against kidney cancer. After repeat chest and abdominal CT scans showed no evidence of612

esidual or recurrent disease, DQ then began an eight-cycle course of intensive interferon, whichhe completed in August of 1991.Thereafter, DQ did well until November 1991, when he noticed a lump in the left parietal-occipitalregion of the skull that rapidly enlarged over a period of several days. In early December needleaspiration of the mass confirmed “Adenocarcinoma, consistent with metastatic renal tubularcarcinoma.”A subsequent CT of the head indicated that the tumor had penetrated through the skull into thecranium, as the report states:“There is a lytic lesion within the left parietal bone with an associated enhancing soft tissue mass,consistent with a metastasis. There is intracranial extension of the enhancing soft tissue, as well asextension into the subcutaneous tissues of the left parietal scalp.”A bone scan revealed “a large focal area of increased radiopharmaceutical uptake with aphotopenic center consistent with metastatic disease in the left occipital region of the skull.” A CTscan of the chest indicated “Small nodule at the left lung base…which may be an area of fibrosis asdescribed. Two other smaller densities in the middle lobe and the left lower lobe as described ofquestionable significance.” However, these lung findings had not been reported on the chest CT ofDecember 1990.DQ then began a one month course of radiation to the skull mass, totaling 4000 rads and completedin January 1992. Despite the treatment, the tumor regressed only marginally. DQ, having been toldhe had incurable disease, began looking into alternative approaches, learned of my work anddecided to pursue my protocol. When we first met in January 1992, only a week after he hadfinished radiation, DQ reported significantly diminished energy, along with a 20 pound weight lossoccurring during the previous six weeks. On exam, I immediately noticed a lemon sized masssticking out of his skull in the left parietal area.Shortly thereafter, DQ began his nutritional protocol, complied well and within weeks reported asignificant improvement in his energy and well being, as well as a 20 pound weight gain. Afterthree months on his nutritional protocol, the previously noted large skull mass completely resolved.A repeat bone scan in June 1993, after DQ had completed some 16 months of treatment, revealed“No evidence of bony metastatic disease.” Not only had the lesion disappeared, but the underlyingskull had healed. Today, nearly 15 years since he first consulted me, DQ remains completelyadherent to his treatment, is in excellent health and cancer-free.Several points need mentioning. Renal cell carcinoma once metastatic is a very deadly disease:DeVita reports a median survival of only 50 days for patients with stage IV kidney cancer, despitetreatment.4 This neoplasm resists not only chemotherapy and immunotherapy, but radiation aswell. In this case, DQ’s doctors suggested radiation not as a potential cure but as palliation, hopingto slow the spread of the tumor into the brain. In any event, the response was negligible. Whilesome radiation oncologists report that at times, the benefit of radiation therapy might continue forup to two months, DQ showed significant response only after his third month on his nutritionalprogram. Furthermore, although his radiologists initially downplayed the new findings on the chestCT in late 1991, in retrospect these lesions may have indicated the beginnings of explosive spread.CASE 15Patient UB: A 6.5-Plus Year Survivor of Renal Pelvic CancerIn July of 1989, Patient UB, at the time a 66-year old Caribbean woman, first developed hematuria.Cystoscopy revealed only a benign urethrocoele, and a right retrograde pyelogram showed noabnormalities. Subsequent urine cytology in January 1990 was negative but in May 1991 sheconsulted her urologist again after noticing blood in her urine. According to the physician’s notes,this time “urine cytology showed atypical cells on 2 occasions and malignant cells in one specimen.613

Repeat IVP showed a defect in the right renal pelvis.”When repeat cystoscopy in June 1991 revealed a normal bladder mucosa, but significant blood inthe right ureter, her urologist suspected she “most likely has a right renal pelvis tumor and haveadvised her family that she will most likely need nephro-ureterectomy.” The patient then agreed toa needle biopsy of the right renal tumor, which showed, according to the patient and her family,renal pelvic cancer – though we do not have the actual pathology report of this test in ourpossession.When UB learned of our approach from her daughter who lives in the United States, she cancelledsurgery despite the urgings of her urologist and decided to proceed with our treatment. During ourfirst session in July 1991, she reported intermittent right flank pain and urethral burning onurination, but no other symptoms. I urged her to reconsider surgery, which I explained could becurative if the disease proved localized. She adamantly held her course, stating that she had hadenough surgery in her life – she had years early undergone hysterectomy - and would not allow anymore, whether I would accept her as a patient or not. So, with her point well made, we agreed toproceed.She proved to be a very compliant patient and did well clinically, with rapid resolution of her flankpain and no further episodes of hematuria. On her home island, she studiously avoided contact withall other doctors despite my wish she consult with them at least on occasion. Since she had noinsurance, frequent testing to monitor her progress was simply out of the question – not that shewould have agreed to it anyway. But in October 1995, after she completed four years on ourtreatment, she did allow an abdominal ultrasound, which revealed a normal right kidney except fora 2.3 cm simple cyst in the pole. Otherwise, the report states: “No solid tumor mass seen. The leftkidney and the remainder of the abdominal organs were normal in appearance.”During the first four years on therapy, UB did return periodically to New York for re-evaluations.After 1995, she could not afford the expense of the trips, so I agreed to follow her by phone. My lastcontact with her was in 1998, after she had been on the program for 6.5 years. At that time she wasfeeling well, with no complaints.In this patient, her resolution of signs and symptoms, her lack of disease spread and her longsurvival all indicate a good response to treatment, particularly since she refused all orthodoxinterventions including surgery. Furthermore, ultrasound studies after four years on treatmentconfirmed the previously documented renal pelvis tumor had resolved completely. Unfortunately,we never received the actual pathology report of the needle biopsy, so her records are in that senseincomplete. But the patient and family members carefully described the procedure and the resultsthat had been reported to her. And, we do have the urologist’s discussion of the positive cytologyand IVP findings to confirm the diagnosis of cancer. Despite the one missing document, I includedher because she did so well following only our nutritional regimen.CASE 16Patient IL: A 4.5-Year Survivor of Colon CancerPatient IL is a 57 year-old man with a family history pertinent for a brain cancer in his mother,colon cancer in an uncle, and lung cancer in a second uncle.He himself had generally been in very good health when beginning in 2000, he noticed a change inhis bowel habits, including increased mucus in his stools, chronic indigestion, bloating and what hedescribed as gas pains. He adopted a whole foods, vegetarian way of eating hoping for some relief,but over time his symptoms only worsened.In mid 2001, he first noticed intermittent bright red blood in his stools. Some months later, inOctober 2001, he developed symptoms consistent with a bowel obstruction, including severe pain,bloating, abdominal distension, and an inability to move his bowels. When the symptoms resolved614

after several hours, he chose not to seek medical attention.Several weeks later, in November 2001, the symptoms returned with a vengeance. He hoped onceagain to ride out the crisis, but over a three-day period the pain, bloating and distension worsenedto the point he finally went to the local emergency room. A barium enema revealed an “apple core”lesion in the sigmoid colon indicating a tumor. When a subsequent sigmoidoscopy revealed acomplete obstruction, the patient underwent emergency laparotomy, resection of the sigmoid colonalong with the tumor, and placement of a temporary colostomy. The surgeon also discovered, as hisoperative note reports, “palpable nodules in the liver, which I felt to be more cystic than solid, butthere were a couple studs that were solid.” He removed one of the liver lesions for evaluation.The pathologist’s summary describes a large colon tumor, but doesn’t give exact dimensions,though it states “The mass locally grossly appears to extend to the underlying adipose tissue,” anddefines the tumor as “moderately differentiated adenocarcinoma, extending through the bowel wall,and present on the serosal surface.” Though cancer had infiltrated two of nine lymph nodesexamined, the liver tissue seemed most consistent with a benign hemangioma.Postoperatively, a CEA test, a tumor marker for colon cancer, came back elevated at 5.1 (withnormal less than 3), an indication of remaining malignant activity. No CEA had been done beforesurgery, so there were no results for comparison.IL did subsequently meet with an oncologist who suspected the tumor had invaded the liver, despitethe negative biopsy. He insisted chemotherapy needed to begin quickly, but upon questioningadmitted if the cancer had indeed spread, treatment would do little. IL, who already had a stronginterest in alternative medicine, decided to refuse conventional treatment and instead began selfmedicatingwith a variety of nutritional supplements. After learning about our work from a localchiropractor, he chose to proceed with our treatment. He contacted our office in early January2002, but we suggested he come in only after reversal of his colostomy.Since the patient has been rushed into surgery in crisis from an obstruction, no preoperative CTscan had been done. Finally, in mid January, his doctors pushed for a scan, which revealedevidence of multiple metastatic lesions in the liver as the official report describes:“Unfortunately, within the liver there are numerous small hypo-enhancing lesions, some of theseare very hypo enhancing to the point where one might consider cysts, but others are moreintermediate density. 5 mm thick slices were obtained to increase the sensitivity. The largest ofthese lesions is only about 1 x 1.5 cm. These are suspicious for metastatic disease….”The radiologist also noted “very minimal subpleural densities seen at the mid left lung field” whichhe felt “should be rechecked within several months.” In his summary, he reports that “I supposethe liver findings increase suspicions of the left lower lobe findings however my feeling is that thelung changes will prove to be benign…” Quite likely, based on the CT findings, cancer had spreadinto the liver and possibly to the lungs. The negative liver biopsy, the patient was told, might onlyindicate that the liver contained both benign and malignant nodules, as the CT scan seemed toshow.In late January 2002, the patient returned to surgery for reversal of the colostomy and lysis ofadhesions that had formed since the first operation. During the procedure, unfortunately, none ofthe liver lesions were biopsied.When IL was first seen in my office in mid March 2002, he seemed enthusiastic about the therapyand subsequently followed the regimen faithfully. Today, more than 4.5 years on treatment and fiveyears from his original diagnosis, he remains fully compliant and enjoys excellent health.Over the years that he has been my patient, IL has chosen not to undergo any further CT scans, adecision I have respected. He says no matter what the scans show, he wouldn’t agree tochemotherapy nor would he change his treatment. He doesn’t want the radiation exposure, which issignificant, the worry, or the expense. So, I have no idea what has happened to the liver, or itslesions, I only know the patient is alive and well.Even if we disregard the CT liver findings for a moment, a number of salient signs point toward adismal prognosis. The literature reports that patients who initially present with an obstructing615

lesion have a far worse prognosis than those who don’t, even if the disease is otherwise localized.DeVita states in this regard:“The presence of obstruction has been found to reduce the 5-year survival rate to 31%, ascompared with 72% for patients without obstruction.”Furthermore, in this patient’s case, the fact that the tumor had already invaded through the bowelwall and infiltrated into two lymph nodes signaled future trouble. The CEA level after surgery,though only mildly elevated, nonetheless also warned of a future recurrence – regardless of whatmay have been going on in the liver. Harrison’s reports that a high CEA before surgery, whateverthe stage, suggests a poor prognosis:“Regardless of the clinicopathological stage, a preoperative elevation of the plasmacarcinoembryonic antigen (CEA) level predicts eventual tumor recurrence.”IL’s elevated postoperative CEA served as an even more worrisome prognostic indicator. Butfinally, if we accept the expert radiologist’s conclusion that cancer had infiltrated the liver, theprognosis turns dire. DeVita reports median survivals in the range of 4.2 to 8.7 months for patientsdiagnosed with metastatic colon cancer receiving aggressive chemotherapy.2 In a large-scalestudy. Manfredi et al report 1- and 5-year survival rates were 34.8% and 3.3% for synchronousliver metastases (meaning liver metastases occurring at the time of the original diagnosis of coloncancer).4 These statistics include patients with solitary liver lesions, which can at times be resectedalong with the primary colon tumor, allowing for long term survival. In this case, IL, with multiplemalignant appearing tumors on CT scan, not only has far outlived the predicted lifespan but hassuccessfully avoided the toxic treatments his oncologist insisted five years ago needed to be done.CASE 17Patient FK: A 19-Year Survivor of Breast CancerPatient FK is a 71 year-old woman who had been in good health when in mid-1984, she firstnoticed a right breast mass. She was referred for a breast biopsy, which proved to be benign.However, within a month of the procedure, her health began to decline rapidly: she developedgradually worsening fatigue, paresthesias and chronic wheezing. Her internist reassured her,telling her "not to worry."After FK suffered a gradual weight loss in early 1985, in April her right breast and axillary regionsuddenly enlarged, turned red and painful. Her physician, assuming she had an infected breast,prescribed antibiotics, but the breast swelling only worsened and in August 1985 she was admittedto a local hospital for evaluation. On exam, FK was found to have a malignant appearing 8 by 8 cmmass, confirmed as cancer by biopsy. Hormone receptors were negative.The tumor was thought far too large for resection, so in September 1985, FK began radiotherapy tothe chest wall, eventually receiving a total of 5100 rads. After completing treatment, she underwenta right modified radical mastectomy, with the pathology report describing infiltrating ductalcarcinoma of the breast, involving 17/17 axillary nodes at all levels.Shortly after surgery, FK began chemotherapy with CMF, a protocol she continued for the next twoyears. In August 1987, while still on treatment, she developed pain in her ribs and sternum. A bonescan in September 1987 documented increased activity in the sternum and two right anterior ribsconsistent with metastatic disease. X-ray studies confirmed probable sternum metastases.Since she had developed recurrent disease while receiving aggressive chemotherapy, FK beganinvestigating alternative approaches to cancer. She learned of my work and first came to my officein December 1987, while she still continued chemotherapy. At that time, she complained of fatigueand severe depression, particularly worse after each dose of chemotherapy.After beginning her nutritional therapy in late 1987, she proved to be a very determined andcompliant patient. Initially, because her oncologist had so frightened her with his dire prognosis,she continued on single agent chemotherapy, methotrexate. Since she had already failed the CMF616

egimen which included the drug, this approach didn’t make much sense to me, but her oncologist,who already announced her disease had reached a terminal phase, apparently hoped the treatmentmight extend her life a few months. Usually, we discourage patients from beginning our program ifthey will be continuing chemotherapy, but in this case, I agreed to the combined approach. Once onher nutritional regimen, FK reported a dramatic improvement in her general health, with resolutionof her bone pain and depression. She continued chemotherapy intermittently for five years withmethotrexate and later vincristine, before finally giving it up entirely and continuing only on mytherapy.For many years, she avoided radiographic testing until May 2001, when a bone scan showed thatthe previously evident lesions had resolved completely. The official reports “No definite abnormaluptake of radiotracer suggesting skeletal metastasis.” Today, 19 years after her recurrence, and 21years since her original diagnosis of aggressive disease, she remains in excellent health with noevidence of cancer.Although her course was initially complicated because she continued chemotherapy, at heroncologist’s insistence, any drug effect can be discounted since she had developed metastaticdisease while completing a two year course of chemotherapy. Also, chemotherapy, no matter thetype, does not cure metastatic breast cancer into the bone. To put this unusual survival inperspective, in a comprehensive evaluation of women diagnosed with invasive breast cancer, allreceiving conventional treatment, Elder reports a 2.4 year median survival after diagnosis of bonemetastases.3CASE 18Patient IK: A 16-Year Survivor of Breast CancerPatient IK is a 64 year-old woman with a strong family history of breast cancer. She had previouslybeen in good health when in the fall of 1986, routine mammography revealed a suspicious mass inthe left breast, confirmed by biopsy as ductal carcinoma in situ. Although her surgeon suggested amodified radical mastectomy, IK insisted a lumpectomy be done. The surgeon agreed, and removedthe cancerous tumor. Since she had no evidence of metastatic disease, her doctors did notrecommend additional adjuvant treatment.She subsequently did well until July of 1989, when her physician detected a mass in the right breast.She underwent lumpectomy as well as excision of a 3 cm right axillary mass that proved to be apoorly differentiated adenocarcinoma, estrogen and progesterone receptor negative, invading andlargely replacing the adjacent lymph node. After surgery, an abdominal ultrasound revealed adensity on the right lobe of the liver consistent with metastatic disease. A needle biopsy of thehepatic lesion confirmed metastatic carcinoma, and a bone scan showed “multiple focal areas ofincreased activity in the spine consistent with metastatic carcinoma.”IK then began chemotherapy with CAF, a very aggressive protocol which she tolerated poorly. Inlate 1989, after completing three cycles, she refused further treatment and for several months, shedid nothing before visiting Stanford in the spring of 1990 for a second opinion. There, afterreviewing the previous biopsies and scans, the physicians concurred with the diagnosis ofmetastatic disease to the liver. The Stanford note reports “The diagnosis is confirmed and the liverinvolvement has been documented by the Stanford Pathology Laboratory.”Her doctor at Stanford recommended she immediately resume chemotherapy with CAF, but onceagain, IK refused to consider further orthodox therapy. Instead, after learning of my work, shedecided to pursue my program and was first seen in my office in April of 1990.She was quite ill at the time, suffering chronic pain in her liver. After returning home and beginningher regimen, the liver pain was so severe she required MS Contin for comfort. She also sufferedfatigue and malaise lasting many months, before she finally began to improve. When I saw her for a617

eturn evaluation in May 1991 - a year after she had begun her nutritional protocol - she felt muchstronger and her abdominal pains had largely resolved. Unfortunately, she began to feel so wellthat without my knowledge, she subsequently discontinued her protocol, assuming she was "cured."In early July 1991, she called me very distraught, having just suffered a grand mal seizure, andadmitted she had been off her protocol for several months. A CT scan of the brain revealed a highdensityepidural mass in the left sphenoidal ridge and a small low density area in the righttemporoparietal region. The radiology report reads “Both areas were heterogeneously enhancedwith contrast medium and appear to be metastatic brain lesions.”Her doctors immediately recommended radiation to the brain, which IK refused. Instead, sheresumed her full nutritional program with renewed dedication, quickly improved and never hadanother seizure. Follow up CT scans of both the head and abdomen in April 1992, less than a yearafter her recurrence, were completely normal – the previously noted liver and brain tumors weregone. The report of the head CT reads “There is no mass or mass effect…There is no evidence ofmetastatic disease…Normal CT scan of the head.” The summary of the abdominal scan states:“Normal CT scan of the abdomen.”Since that time, IK has had an up and down history on my program, with periods of goodcompliance and periods of less than good compliance. I haven’t seen her in my office in some years,but heard from friends that she is still doing well and still taking enzymes. Our last formal contactwith her was in October of 2005, when she appeared to be doing fine, 15 years after her diagnosisof terminal metastatic breast cancer.Her course with such terrible disease is certainly unusual. IK also served as her own “control;”when she followed the program she did well, and when she didn’t comply, the cancer came backwith a vengeance. The disease then completely regressed when adherence to therapy improved.We usually tell new patients coming to us with a history of metastatic cancer that they need tofollow their nutritional regimens indefinitely, and must never assume they are completely free andclear. Dr. Isaacs and I think of cancer as a chronic degenerative disease, akin to diabetes, that canbe managed successfully for years as long as patients follow their diet and take their enzymes.When a patient falls off the wagon, as in this case, cancer can return and cause havoc. Reneweddedication to the treatment can usually get the situation back under control.Regardless of her compliance lapses, IK’s survival is extraordinary. As the medical literaturedocuments, breast cancer, when metastatic to either the brain or liver, is a deadly disease. In aseries of patients with brain metastases specifically, Lentzsch et al report a median survival of 23weeks for those with more than one lesion, despite aggressive conventional treatment.4 In a groupof patients with at least one lesion receiving supportive care only, the authors describe a mediansurvival of 5 weeks.Eichbaum et al studied a group of 350 women with breast cancer that had metastasized to theliver.5 The authors describe a median survival, regardless of the conventional treatment given, of14 months, somewhat better than the numbers for brain metastases, but still dismal.In this case, IK had evidence of liver, brain and bone metastases, as deadly a combination as canbe imagined.CASE 19Patient AR: A 16-Year Survivor of Breast CancerPatient AR is a 72 year-old woman who had generally been in good health when in July 1990, shedetected a left breast mass. Mammography revealed, as the official report states, “several areas ofincreased density with the upper outer aspect of the left breast which appear markedly asymmetricas compared to the right breast and which have the appearance of mass densities with irregularmargins.” After an ultrasound confirmed a 1.8 cm density in the left breast, the patient was618

scheduled for a lumpectomy.A routine preoperative chest X-ray showed nothing, but a chemistry blood screen demonstratedmarkedly elevated liver functions tests with an alkaline phosphatase of 154 (normal less than 140),AST of 89 (normal less than 50) and a ALT of 138 (normal less than 55). But an abdominalultrasound revealed a normal liver with “no metastases.” Then in September 1990, AR underwentexcisional biopsy (lumpectomy) for what proved to be a much larger tumor than had been expectedbased on the mammography and ultrasound findings, measuring 4 X 3 X 3.2 cms. The mass, whichcould not be completely removed, was found consistent with a well-differentiated mucinousadenocarcinoma of the breast, estrogen and progesterone receptor positive. The pathology reportstates ominously “The lesion extends to the margins of the specimen submitted on the lateral andundersurface.”After a bone scan revealed only arthritic changes, AR met with her surgeon who insisted amastectomy was now necessary since residual cancer remained in the breast. He suggested thatafter the procedure, she undergo a course of intensive multi-agent chemotherapy. AR also met witha radiation oncologist and a medical oncologist, who both agreed that because of the size of thetumor, she required, after surgery, radiation followed by chemotherapy.However, AR, as she later was to tell me, had seen “too many people cut to pieces and poisonedonly to die,” for her to agree to any further conventional treatment. She refused additional surgery,chemotherapy, and radiation, and instead investigated alternative approaches. After learning of mywork through a friend, she first consulted with me in October 1990 and thereafter followed herprogram with great determination. As an quick benefit, within weeks her liver function testsnormalized.AR followed her program diligently for some eight years, until 1998, when I last saw her in myoffice. During this time, she refused all testing other than routine blood analysis, saying shewouldn’t change her therapy regardless of what the studies showed. Sixteen years out from heroriginal diagnosis, she is in excellent health, active with various activities and hobbies. She followscomponents of the program, as much as her finances allow, and still refers patients to me regularly.AR, though lacking evidence of metastatic spread at the time of her original diagnosis, certainlyrepresents a remarkable success. The size of the original tumor, coupled with the fact that residualcancer remained after the original lumpectomy, portended a troubling prognosis, even had sheagreed to the proposed chemotherapy and radiation. On my program, however, she has enjoyed ahealthy and cancer free life.I included her because we have in our practice a number of women who despite evidence ofsubstantial residual cancer in the breast after a positive biopsy, refused any further conventionalintervention, instead choosing only our program for treatment. Though these women have generallydone very well for very long periods of time – 16 years in the case of AR – we no longer acceptpatients with localized breast cancer who do not proceed with recommended surgical procedures.Our decision has not been dictated by a negative clinical experience, but rather the extraordinarilyhostile legal environment that exists for alternative practitioners such as ourselves. Standard-ofcarecriteria require a woman like AR undergo further aggressive surgery, and the world wouldneed a consciousness shift before we would consider taking on such patients again.CASE 20Patient VE: A 14.5-Year Survivor of Breast CancerPatient VE is a 62-year old woman with had a long history of fibrocystic breast disease, firstdiagnosed when she was 19 years old. Thereafter, her doctors followed her closely with frequentmammography, and two biopsies showing benign changes.In 1991, mammography again indicated dense fibrocystic breasts as well as a new “1 cm nodular619

density in the upper and axillary portions of the right breast…This contains internalmicrocalcifications in a diffuse pattern, and represents a new finding….” Her doctorsrecommended biopsy, which VE, already interested in alternative approaches, refused, insteadchoosing to follow a nutritional program under the supervision of a local practitioner. However,repeated mammography in March 1992 showed a worsening picture:“Once again, I note small nodule in the upper outer right breast, in association with manymicrocalcifications. Number of microcalcifications has increased slightly during the interval.”At that point, in the spring of 1992, VE underwent needle biopsies of eight lesions, four of whichproved positive for ductal carcinoma. Since she had diffuse disease throughout the breast, hersurgeon insisted she needed mastectomy. However, the patient decided to refuse all further surgeryand any other conventional treatment, instead opting for our regimen.When VE first consulted me in 1992, she had, on exam, very dense nodular breasts but seemedotherwise in good health. During our lengthy initial interview, I encouraged her to reconsidersurgery, which for early stage breast cancer can often be curative. In a calm and determined wayshe explained her decision to refuse disfiguring surgery or toxic conventional treatment, whether Ichose to be her doctor or not, so I agreed to treat her.She subsequently followed her regimen diligently, and over the years has done extremely well,though declining all further testing. Today, she adheres to a maintenance protocol and appears tobe in excellent health, now 14.5 years from her biopsy diagnosis.As in the case of AR, Dr. Isaacs and I most likely would not agree to treat a patient like this today.The legal climate for alternative medicine remains repressive, the power and authority ofconventional medicine, despite its well documented and rather glaring limitations, is formidable.However, I am gratified by the success of patients AR and VE, and the others like them in ourpractice, who were able to avoid all aggressive surgery as well as toxic drug and radiationtreatments. They still have their breasts, their lives, and their health.CASE 21Patient BV: A 15-Year Survivor of Breast CancerPatient BV is a 67 year-old woman who had been in good health when routine mammography inOctober of 1991 revealed a suspicious breast mass. In late 1991 she underwent biopsy andlumpectomy, with removal of a 2.1 cm. tumor confirmed as in situ and infiltrating ductalcarcinoma. Though no nodes were sampled, a bone scan in December 1991 as part of routinefollow-up testing demonstrated increased uptake in the right proximal femur. An MRI in January1992 documented a lesion on the right greater trochanter consistent with metastatic disease. Theofficial report reads “A solitary lesion is noted distal to the right greater trochanter…most likelyrepresenting a metastatic lesion…”The patient did meet with an orthopedic surgeon who suggested a course of aggressive surgery withhip replacement followed by radiation to the hip. Her breast surgeon insisted BV proceed withmastectomy and subsequent radiation to the chest wall. However, after learning of our approach,BV refused all further conventional interventions, instead choosing to proceed with my treatment.When I first saw BV in early 1992, she reported severe fatigue and chronic right hip pain, severeenough that she had gone on disability from her job. After beginning her nutritional regimen, sheproved to be a very determined, compliant patient. During her first months on therapy, she sufferedmigratory aches and pains, particularly severe in the right shoulder and hip, but these graduallyresolved. In fact, after a period of some months she felt so well she returned to work full time.Repeat bone scans in May 1992 – five months after BV began her treatment with me – showed,according to the report, “No definite evidence of metastatic disease.” A follow-up scan in June1993 was again clear, and today, nearly 15 years after she first consulted me, BV remains620

compliant with her full regimen, and disease free.Her case is very straightforward. At the time of diagnosis, a bone scan and MRI documented alarge tumor in her hip that regressed while she followed only her nutritional program.Elder et al report a median survival of 2.4 years for women with breast cancer metastatic to bone,3somewhat better statistics than for those diagnosed with brain or liver metastases. However, thesenumbers reference patients aggressively treated with conventional modalities such as surgery,chemotherapy and radiation, all of which BV refused.CASE 22Patient GX: A 9-Year Survivor of Breast CancerPatient GX is a 70+ woman with a family history pertinent for both colon and breast cancer. Shehad been in good health when in 1986, after a suspicious mammography, a biopsy confirmedinfiltrating ductal carcinoma. She underwent right mastectomy, and three nodes were foundinfiltrated with metastatic cancer. She subsequently completed a six-week course of radiation to thechest wall, but received no chemotherapy. She did begin tamoxifen.In early 1989, after she developed rectal bleeding, sigmoidoscopy revealed a 2 cm lesion in thesigmoid colon that was biopsied and found consistent with moderately differentiatedadenocarcinoma. Prior to the planned colon surgery, CT scans showed no abnormalities in theabdomen, but a lesion in the lower right lung not evident on prior X-rays. The following day, thepatient underwent exploratory laparotomy and resection of the lower sigmoid colon for whatproved to be Dukes’ C disease, meaning the cancer had spread into regional lymph nodes. At thattime, the lung finding was discounted as insignificant.GX then completed six weeks of chemotherapy with 5-FU, followed by six weeks of radiation to thelower abdomen, then another six weeks of 5-FU. In addition, she continued on tamoxifen for herpreviously diagnosed breast cancer. Certainly, at this point, GX faced potential disaster, with twodifferent cancers, each metastatic to local lymph nodes – a poor prognostic indicator for either. Butshe actually did fairly well, with subsequent CT scans confirming that the solitary pulmonarynodule had stabilized. In 1996, after she had been on tamoxifen for ten years, her doctors suggestedthe drug be discontinued, however a year later, in March 1997, a routine chest X-ray showedseveral new lesions. The radiology report describes “Suspicion of right lung nodules as above…aCT scan is recommended.”A CT scan in April 1997 revealed “Several 1 cm or smaller non-calcified pleural based lungnodules are noted on today’s examination in the region of the right upper and lower lobes…”Her surgeon, a long time friend, told GX she had metastatic disease that might have originatedfrom either the breast or colon primaries. He did not advocate for biopsy of the lung lesions sincehe felt the findings were clearly indicative of cancer. Nor did he press the case for additionalconventional treatment when GX made it clear she would never agree to such an approach again.She had already learned of our work, and had chosen to proceed with us.I first saw GX in my office in April of 1997, shortly after her diagnosis of recurrent disease. Adetermined, compliant and dedicated patient, I don’t think she has missed a supplement in nine anda half years. And the results have been gratifying; a chest X-ray in April of 1998, a year after shehad begun her nutritional program, showed no change in the left nodular density, but resolution ofa right lower lung lesion and partial regression of a third right lower lobe nodule. In March of1999, after GX had completed two full years of treatment, the report of a chest x-ray describes“Clear lungs.” All the previously noted lesions were gone.After those clear scans, GX continued doing well. In 2004, seven years after beginning our therapy,mammography revealed calcifications and nodularity in the left breast that on review, had been621

present on earlier studies dating back to 1993. After biopsy confirmed carcinoma, I agreed that sheshould proceed with mastectomy since the left breast had been problematic for more than a decade.The breast contained a very small, 0.3 cm area of carcinoma, with no lymph node involvement. Idon’t believe this to have been a new lesion, but suspect her breast was so dense and fibrotic, withmultiple long standing calcifications, that the blood supply to the area had probably beencompromised, allowing this small cancer to exist though her metastatic disease resolved. I havemade some changes in her protocol, which she continues to follow faithfully. Two years later, nownine and a half years since her diagnosis of metastatic disease, she continues doing well.I have decided to include GX among my breast cancer survivors, though ultimately we don’t knowwhether the lung lesions were breast or colon in origin. In either case, such spread invariablyproves fatal, usually quickly. This patient’s long term survival, coupled with radiographic evidenceof tumor regression while following her nutritional protocol, certainly demonstrate a ratherremarkable course for what would normally be a deadly situation.CASE 23Patient EZ: A 7-Year Survivor of Breast CancerIn July 1987, after Patient EZ first noticed a left breast mass, she underwent first a needle biopsyconfirming carcinoma, then a modified radical mastectomy. The pathology report describes mixedcolloid carcinoma and intraductal and infiltrating duct carcinoma, with 1/7 nodes positive formalignancy. A metastatic work-up, including a bone scan, was negative. When estrogen receptorstudies came back positive, she started on tamoxifen.EZ did well until September 1988 when routine blood testing revealed an elevated CEA at 14. A CTscan showed two lesions in the liver, and a bone scan demonstrated a right rib lesion, all thoughtconsistent with metastatic disease.In November 1988 EZ began chemotherapy with CMF, which she tolerated poorly. After six cycles,a repeat abdominal CT scan in April 1989 showed worsening disease. Though the previously notedtwo hepatic lesions remained unchanged, the radiologist noted a third new lesion, 2 cm in diameter.Since her disease had progressed, her oncologist added vincristine to the regimen, but EZ sufferedsuch severe side effects, including debilitating nerve pain, she decided to discontinue all furtherchemotherapy. At that point, she was told to consider calling in hospice.Instead, EZ began looking into other approaches, learned of our treatment and first consulted withme in June 1989. After returning home, an abdominal CT scan before she began her nutritionalregimen revealed that the liver disease had only worsened despite vincristine added to thechemotherapy mix:“There are several low attenuation lesions about the liver, the largest measuring 3 cm. In thelateral segment of the left lobe of the liver. This lesion appears enlarged since the priorexamination. Additionally, a new lesion is noted about the right lobe of the liver. These likelyrepresent metastatic disease.”Subsequently, EZ pursued her program with great dedication. Her local oncologist agreed to followher since she lived some distance from our office, and after she had completed nearly a year on herprotocol, a CT scan of the abdomen in April 1990 revealed significant improvement as documentedin the written report:“Comparison is made to the prior examination on 7/12/89. Since then, the metastatic lesions in theliver have decreased slightly in size. The low attenuation lesion in the medial segment of the leftlobe now measures 2 cm in diameter as compared to 3 cm on the previous examination. That in theanterior segment of the right lobe now measures 2 cm as compared to previous measurement of 2.5cm in diameter. No new lesions are identified.”A bone scan in November of 1990 showed resolution of the previously noted rib lesion:“Comparison is made with the patient’s last similar examination performed in October 1988. The622

only substantive interval change is the apparent resolution of an inferior right rib lesion…”EZ thereafter continued on her nutritional protocol and in April 1991, nearly two years afterbeginning her program, a CT scan revealed continued improvement:“Multiple small liver lesions most of which measure less than 5 mm in diameter in the medialsegment of left lobe as well as anterior and posterior segments of right lobe.”A CT scan 14 months later, in June 1992 – after she had completed three years of treatment with us- demonstrated that the largest tumor, which previously had been solid, now appeared to be cystic:“Three hypodense hepatic lesions remaining, the largest of which is located in the posteriorsegment of the right lobe of the liver, measuring approximately 1 cm in diameter, and has the CTcharacteristics of a simple cyst. The other hepatic lesions are smaller on the current studycompared with the prior study (of 4/5/91)."However, during the summer of 1993, EZ – after enjoying excellent health for four years whilepursuing her nutritional program – reported gradually worsening fatigue. An ultrasound of theliver in July 1993 revealed new progression of the liver lesions, with one now measuring 7.5 cms indiameter.The sudden worsening I find perplexing even today, years later. Over time, as patients improve, insome cases as cancer becomes less frightening, compliance can falter. As best as I could tell, EZseemed to be compliant. I do know that her doctor, although willing to follow her, never supportedher choice of treatment and repeatedly expressed his belief my therapy couldn’t work. Suchcomments can, we have found, influence a patient’s determination to stay with the treatment.Also, though I did make some adjustments to her program, today I would have pushed the dose ofenzymes far more aggressively than I did in 1994. Often, such a change turns the situation around.In any event, EZ continued on her program until April 1994 when she decided to stop all therapy,nearly five years after she had started with me. She wrote me a gracious note, thanking me for theyears of generally healthy good life she had never expected, based on the terminal prognosis givenher in 1989. I didn’t hear from her again, until learning of her death more than two years later inAugust 1996 – some seven plus years after she had first consulted me in June of 1989.Eichbaum et al describe a median survival, regardless of the conventional treatment given, of 14months for women with evidence of metastatic breast cancer into the liver, despite aggressiveconventional treatment.5 In this case, EZ had documented bone metastases as well as multiple liverlesions. Certainly, with her stage IV condition, the evidence of progressive disease despiteaggressive chemotherapy, at the time she began our nutritional therapy EZ faced a lifespan thatwould normally be measured in months. Her seven plus years survival, her generally excellenthealth during much of that time, and the documented regression of liver and bone lesions over afour year period while pursuing only my regimen represents a most unusual course for a mostunusual patient.CASE 24Patient GR: A 7-Year Survivor of Breast CancerPatient GR received radiation to the chest as a teenager for treatment of keloids but otherwise hadbeen in good health when in late 1986 she developed a left breast mass. After a biopsy confirmedcarcinoma, in January 1987 she underwent a modified radical mastectomy for what proved to beadenocarcinoma, estrogen receptor positive, with metastatic disease in 8 of 23 nodes – a very poorprognostic indicator. However, chest X-ray, bone scan and abdominal ultrasound showed noevidence of metastatic disease. Postoperatively, GR completed a six-month course of adjuvantchemotherapy with CMF, followed by tamoxifen.GR did well until late 1990 when she developed pleuritic chest pain which her local doctor treatedwith antibiotics. She improved somewhat, but then her symptoms worsened in the spring of 1991.623

After a chest x-ray in April 1991 revealed a left pleural effusion, she underwent thoracentesis, withcytology positive for the presence of malignant cells. A bone scan was negative. Tamoxifen wasdiscontinued in favor of Megace, a synthetic progesterone analog used to treat breast cancer, buther respiratory symptoms only worsened. A repeat chest x-ray in May 1991 demonstrated apersistent pleural effusion, as a note from her oncologist confirms:“Chest x-ray today reveals significant amount of fluid, certainly reaccumulation since her post-tapfilm...The patient will stay on Megace 80 mgs b.i.d…..She was encouraged not to take unapprovedmedications for her cancer.”During a follow-up visit in July 1991, her situation seemed to beworsening:“The patient has a significant amount of fluid which would make be (sic) think that the Megace isnot working particularly well…”A chest x-ray in August 1991 showed some slight improvement, described as “Moderately large leftpleural effusion, smaller than on the previous examination.” Since hormonal therapy had failed tocontrol her disease, her doctors suggested aggressive chemotherapy, which GR refused.GR began investigating alternatives, learned of my work and first came to my office in September1991. At that time, she continued on Megace, and reported severe shortness of breath as well as apersistent cough. After returning home, she discontinued the drug, began her nutritional protocoland within weeks noted a significant improvement in her breathing and overall well being. Shethereafter followed her program faithfully, and when I saw her in my office for a follow-up visit inApril 1993, she reported feeling “wonderful,” better than she had in years. Her respiratorysymptoms had resolved and her pulmonary examination was normal. A repeat chest x-ray in April1993 showed no evidence of pleural effusion or mass lesion. The report states:“Lungs are slightly hyperinflated compatible with chronic obstructive pulmonary disease. Therehas been a right mastectomy…No acute pulmonary infiltrates…”For the first five years on therapy, GR enjoyed excellent health. However, she frequently reportedsevere personal stress, including a very difficult divorce involving aggressive legal actions. Overthe years, she admitted the haggling with lawyers had begun to wear her out. By late 1996, she haddeveloped fatigue, pelvic pain and chronic nausea that impeded her compliance with the regimen. ACT scan in November 1996 revealed bilateral ovarian masses obstructing the ureters, as theradiologist reported: “These are complicated appearing masses and the differential could includetumors, endometrioma or abscesses.”A chest CT showed no distinct masses, but:“Loculated low density fluid-like collection in the lower left thorax pleural space….This could beconsistent either with empyema or possibly an area of previously treated pleural metastatic diseasewith thickened pleura.”After ureteral stents were placed to decompress the kidneys, a biopsy of an ovarian mass confirmedrecurrent, metastatic breast cancer. Though her doctors insisted GR begin chemotherapy at once,she refused, instead choosing to resume, as best as she could, her nutritional program. Withinweeks, she began to improve in terms of her energy and well being. Unfortunately, eventually thestents obstructed again, and the nausea, anorexia and fatigue returned. By the spring of 1997 GRcould no longer follow the full program and at my suggestion and that of her local doctors restartedtamoxifen.Subsequently, as she struggled to continue my regimen, she was seen by a nephrologist at the MayoClinic in Arizona, but despite repeated stent changes, her kidney function never returned to normal.Nonetheless, to her doctors’ surprise, she survived another year, ultimately dying in April 1998,nearly seven years after she had first consulted me.Though this patient did ultimately succumb, it’s important to emphasize that breast cancerrecurring after aggressive chemotherapy and hormonal blockade, particularly when invading anorgan system such as the lung, usually kills within months. In this patient’s case, after developingsevere pleural effusions in the spring of 1991, she responded only slightly to Megace. However,while being treated solely with our therapy, she had a quick clinical response with resolution of624

effusions as documented by x-ray studies in April 1993. Her seven years of life after her recurrence,and her excellent health until the last year, certainly illustrate a remarkable course.Sometimes it’s productive to look for explanations why one patient survives terrible disease, andanother doesn’t. In her case, she herself said repeatedly the terrible stress in her life “was killingme.” Perhaps ultimately it did. Perhaps her body just wore out, after all she had been through, withthe disease and the previous toxic treatment. But her family remains to this day grateful for theunexpected years she had with them.CASE 25Patient AR: A 14+ Year Survivor of Breast CancerPatient AR is a 74 year-old woman who had been generally in excellent health when she firstdetected a left breast nodule in August 1991. She did not immediately seek medical attention,instead deciding to self medicate with a number of nutritional supplements and dietary changes.When the mass did not regress, in March 1992, at the urging of a friend, she underwentmammography, which revealed a suspicious left breast lesion.In April 1992, AR proceeded with a left modified mastectomy. The pathology report describes twodistinct lesions, one 2.0 cm in diameter, the other 1.6 cm, both consistent with infiltrating ductalcarcinoma, estrogen receptor positive, progesterone receptor negative. Two of 13 evaluated lymphnodes were infiltrated with invasive carcinoma.Her surgeon strongly recommended a one-year course of chemotherapy because of the positivelymph nodes, but the patient, already intent on proceeding with an alternative approach, declinedfurther conventional treatment including hormonal blockade as well as chemotherapy. Then, afterlearning of my work, she was first seen in my office in August 1992.Since that time, AR has been a dedicated, compliant, and very grateful patient. She still diligentlyfollows her regimen, for which she credits the excellent health she has experienced over the past14+ years. She remains very active, travels, and enjoys a number of outdoor activities.Her course was very straightforward: after refusing the recommended chemotherapy and hormonalblockade, she has since followed only my nutritional regimen. Though she had no evidence ofdistant metastasis when she began with me, multicentric disease coupled with lymph nodeinvolvement augered for a poor prognosis. I believe she is an informative case, one of a series ofwomen in our practice diagnosed with node positive disease, who avoided chemotherapy, radiationand hormonal blockade, and the attendant side effects, and experienced long-term disease freesurvival.CASE 26Patient RY: A 7-Year Survivor of Breast CancerPatient RY is a 53-year old woman who in January 1999 consulted her primary care physicianbecause of persistent exhaustion. Blood work studies were unrevealing, but during a follow-upphysical exam in April 1999 her physician detected a lump in the left breast. Mammographyrevealed a worrisome area, confirmed by ultrasound as two distinct suspicious nodules. A biopsyfollowed, documenting, as the pathology report describes, “At least three of these five biopsyspecimens are involved by infiltrating carcinoma of ductal type.”A surgeon then suggested immediate mastectomy, but RY, with a long interest in alternative healingtechniques, decided to delay surgery and instead traveled abroad for a stay at a healing retreat.She admits she hoped that intensive meditation coupled with a wholesome diet might generate aspontaneous remission.625

When she returned home she sought a second opinion at a major teaching hospital in the Canadiancity in which she lives. After the doctors again discussed surgical options, she agreed to a doublelumpectomy in the left breast for excision of the two lesions identified on ultrasound, along withaxillary dissection. In late December 1999, she underwent surgery as planned. The pathologyreport describes a 2.2 cm tumor, high grade III, estrogen receptor positive, with lymphatic vascularinvasion. The tumor extended nearly to the surgical margins, and two additional areas distant fromthe main lesion proved to be cancerous. Cancer had also infiltrated into 13 of 16 lymph nodes, anindication of a dire prognosis.In mid January, at a follow-up visit, her surgeon urged that because of the lymph node involvement,she consent to a course of aggressive chemotherapy. At that point RY, who had learned of our work,decided to proceed with our therapy. When we met for the first time in mid January, only severalweeks after her surgery, she seemed to have weighted the options carefully and said bluntly shewould refuse all conventional treatments.After returning home to Canada, she began my program, which she followed with diligence. InMarch 2000 she did meet, as had already been planned, with an oncologist, whom she reported"went nuts” when she told him she was refusing chemotherapy. After he calmed down, he admittedthat even with aggressive chemotherapy, he could promise perhaps a 5% chance of long termsurvival due to the extensive lymph node involvement at the time of diagnosis.In April 2000, after she had been on our therapy for three months, she detected a new nodularity inher upper left breast. An ultrasound revealed:“Two solid nodules are seen in the left upper outer quadrant....I feel they should be viewed withsuspicion, as they may represent involved lymph nodes. Sonographically guided biopsy isrecommended.”RY chose not to proceed with biopsy, but instead concentrated on her nutritional program.Thereafter, she declined further radiographic testing, stayed faithfully on her nutritional regimen,and today, nearly seven years from our first meeting, enjoys generally excellent health. The leftbreast nodularity long ago regressed.The Adjuvant! Online website provides survival statistics for a variety of cancers, broken down byspecific stage. I was able, on the site, to find numbers that would apply to someone like RY. Inwomen undergoing surgery for breast cancer who have nine or more positive nodes but no evidenceof distant spread, and who receive no adjuvant therapy, only 5.7% will be alive and disease free atten years.6 So, the numbers are better than what experts report for those with breast cancer thathas invaded distant organs, such as the liver, brains or bones, but they are still not great.In this case, the nature of the tumor - grade III/III on the Bloom/Richardson scale – itself portendeda potentially poor prognosis, as did the 13 involved nodes. Importantly, during the initial months ontherapy, on exam and as confirmed by ultrasound, RY had evidence of recurrent suspiciousnodularity which subsequently regressed. In any event, in the seven years that she has been ourpatient, RY has successfully avoided chemotherapy and any other conventional treatment.CASE 27Patient RA: A 4.5-Year Survivor of Breast CancerPatient RA has a family history pertinent for multiple cases of cancer, including breast cancer. Sheherself had a long history of fibrocystic breast disease, followed closely by her doctors at the majoracademic center in the city in which she lives. In 1990, she developed a new left breast mass, thatwas initially not thought to be problematic, based on ambiguous mammography findings. When themass persisted, in May 1991 she underwent aspiration of the nodule, which yielded cells suspiciousfor malignancy. Because of the worrisome findings, coupled with her strong family history of breastcancer, RA decided to proceed with prophylactic bilateral mastectomies. So, in May of 1991, she626

underwent a left modified mastectomy and a right simple mastectomy with lymph nodes left intact.The right breast appeared to be cancer free, but a 1.2 cm lesion in the left breast proved to containboth infiltrating and lobular carcinoma, and four of 18 axillary nodes were positive, a negativeprognostic indicator.After surgery, an oncologist suggested RA enter a clinical trial comparing standard chemotherapyfor node positive breast cancer against a new regimen consisting of Cytoxan, epirubicin and 5-FU,for six full cycles. After RA agreed to participate, she was assigned to the epirubicin arm of thestudy. She tolerated the protocol poorly, experiencing not only chronic nausea and fatigue but apersistent peripheral neuropathy. Despite the side effects, she completed the regimen on schedule inDecember 1991.Thereafter, RA reports her health deteriorated significantly. She describes an unending series ofvarious infections, including chronic cystitis, sinusitis and upper respiratory infections. Then inJuly of 2001, nearly ten years after she had completed chemotherapy, her oncologist noted enlargedbilateral axillary lymph nodes. Her physicians, for reasons I don’t understand, initially suggestedneither biopsy nor treatment. When the lymph nodes did not regress, in December 2001 her primarycare physician ordered ultrasound studies of axillary regions, which showed eight enlarged nodeson the right, two on the left.In January 2002 a biopsy of a right axillary node confirmed metastatic carcinoma consistent with abreast primary, estrogen and progesterone receptor positive. Follow up studies, including a liverspleenscan, chest X-ray and bone scan were all clear.RA then consulted her former surgeon, who suggested that both axillae be “cleaned out,” aprocedure she declined. When in February 2002 her oncologist then recommended notchemotherapy but a trial on tamoxifen, she agreed to the plan. But she also began looking intoalternative approaches and learned of our work.When I first saw RA in May of 2002, she was still taking tamoxifen, but anxious to quit because ofongoing severe side effects. On physical exam, she had evidence of enlarged bilateral axillarynodes. She thereafter began her nutritional regimen, discontinued the tamoxifen, and noted gradualimprovement in her overall health. A variety of chronic symptoms and problems, including fatigue,neck pain, malaise and severe allergies have largely resolved. Today, more than four and a halfyears since starting her nutritional regimen, she remains a determinedly compliant patient, and isin good health with no evidence of enlarged nodes anywhere, including in the axillae. Sincestopping tamoxifen, she has received no conventional therapy.Her case is unusual for a number of reasons. Her bilateral axillary disease developing afteraggressive chemotherapy predicted a dismal prognosis. On her nutritional program, the tumorsregressed and remain so today.CASE 28Patient ZA: A Four Plus Year Survivor of Breast CancerPatient ZA had a family history pertinent for two first-degree relatives with breast cancer, and athird who died of stomach cancer. She had herself been in good health, with a distant history oflocalized melanoma, when in early 1989 she first noticed a painful lump in her right breast.Mammography was unrevealing, but after a biopsy in May 1989 confirmed carcinoma of the rightbreast, she underwent right modified mastectomy. The tumor consisted of infiltrating ductalcarcinoma and in situ carcinoma, estrogen receptor and progesterone receptor negative, but alllymph nodes were cancer free. After a postoperative bone scan and CT scan of her abdomen wereboth clear, she then began a nine-month course of chemotherapy with methotrexate and 5-FUZA did well until March 1993, when she noticed a nodule on the right upper chest wall that both627

her oncologist and surgeon thought was insignificant. Her primary care physician, less sanguineabout the situation, referred ZA to another surgeon who in July 1993 biopsied the lesion, whichproved to be recurrent moderately differentiated adenocarcinoma. A bone scan showed suspiciousactivity in the right third rib, but x-ray studies did not confirm the finding. A CT scan of the chest inlate July 1993 revealed normal lungs but “Multiple tiny areas of low attenuation in theliver….although some of which are intrahepatic vasculature, others are felt to be due tometastasis.”A CT scan of the liver in August documented “Occasional areas of low attenuation throughout theliver… these most likely represent an early metastatic process.”In August 1993, at the urging of her oncologist, ZA began a course of radiation to the chest wall for“local control,” an approach that makes little sense since the disease had already spread into theliver and possibly into the bones. Unfortunately, she suffered such significant side effects fromradiation, including severe burns, that the treatment had to be prematurely discontinued. Heroncologist then insisted she resume aggressive chemotherapy, but the patient, realizing her diseasewas now incurable by conventional standards, refused the drug treatment and began investigatingalternatives. After learning of my work, she decided to proceed with our treatment and firstconsulted with me in October 1993. At the time, she had recovered from her radiation experience,and seemed to be feeling quite well despite her liver disease.Thereafter, for a time she was an extremely dedicated and compliant patient, aware her life was onthe line, and initially she did quite well. A CT scan in February 1994, after she had followed hernutritional regimen for only five months, showed “Overall improvement in the metastatic process inthe liver with some residual areas of low attenuation compatible with a metastasis.” The patient’soncologist, who had so firmly insisted ZA resume chemotherapy after the positive CT scan findingsin August, now claimed she couldn’t possibly have had cancer in the liver, since it wasinconceivable my “bizarre” treatment could have provided any benefit. ZA at that point got herselfanother physician to monitor her local care.When I saw her again in New York in June 1994, eight months after her first visit, she was feelingremarkably well, with excellent energy and well being. However, I saw the first signs of troublewhen she admitted she had gotten careless with the critically important supplements. After Ilectured her at length about the need in her case for not good, but perfect compliance, she returnedhome with renewed dedication.A bone scan in October 1994 was interpreted as “Essentially unremarkable,” indicating thepreviously noted rib lesion had resolved. I next saw her in the office in July 1995, at which time shereported no problems and said she felt “wonderful.”She had no further testing until October 1995, when she had completed two full years on hernutritional protocol. A chest x-ray was normal, and a CT scan of the abdomen with and withoutcontrast showed total resolution of the lesions in her liver. The report reads “Normal CT ofabdomen without and with I.V. contrast.” Her diffuse liver metastases were gone.During the first several years of therapy, we require that all our out of town patients return to NewYork every six months, for a lengthy in-office reevaluation. I find I can learn more about what’sgoing on with a patient after ten minutes face to face, then in a two-hour phone consultation,particularly regarding such life and death issues as compliance. In ZA’s case, though she was nextdue for a return visit in the spring of 1996, in February she called saying she could not come toNew York because of financial considerations. Unfortunately, insurance companies pay only for“standard of care” treatments, and in this case, ZA’s company paid nothing for her nutritionalregimen – despite her several appeals based on the documented response to our regimen. Already,by 1996, her financial constraints – tragically – raised red flags. When strapped, patients tend tocut back on the supplements – an invitation to disaster with advanced deadly cancer.When we spoke by phone in early March 1996, she admitted she had again been feeling so well shehad become sloppy with all aspects of the therapy. She had resumed eating sweets, forbidden foodon the therapy, and was consuming far more animal protein than we had allowed on her particular628

diet. She had cut down the frequency of the coffee enemas, which we find essential for success, andshe had been missing doses of supplements, including the enzymes – the main anti-cancer elementof the therapy. I lectured at length about the need for vigilant compliance and she promised shewould do better.In early July 1996 a bone scan revealed a new lesion in the right seventh rib, consistent with ametastasis. Shortly after, she returned to New York for a visit in the summer of 1996, nearly threeyears after she had begun my program. Although she reported she felt “great,” her compliance wasfar off track and I could see that she had been lulled into complacency. To make matters worse, notonly was she inadequately compliant with my regimen, but a local “holistic” practitioner hadsuggested, without consulting me, that she begin taking a variety of supplements, including thehormone DHEA, which I never would have prescribed for someone with her history.After returning home, in September she developed open sores on her chest wall, I believe directly asa result of damage from the earlier radiation therapy. I urged her to be fully compliant, stick withmy protocol and throw away the supplements from her local doctor. For a time, she did seem to bemore determined, and by mid January, the residual chest lesion had regressed somewhat, to the sizeof a small pea. However, in February, biopsies of a chest wall and right neck nodule confirmedadenocarcinoma.I was due to see her for a return office visit in February 1997, but she again said she couldn’tafford to come to New York. During early 1997, we talked frequently by phone, and though herenergy was generally quite good, she developed a chronic cough. A bone scan in June showed newareas of involvement, and by July 1997, she had been diagnosed with pleural effusions. These weredrained with some symptomatic improvement, but the fluid tested positive for malignant cells. Inever saw ZA in my office after the August 1996 visit, though we kept in touch at least on a weeklybasis throughout much of 1997. As her situation deteriorated, she required multiple thoracentesesfor reaccumulating effusions. By mid fall, she had great difficulty sticking to her nutritionalprogram and she finally died in late December of 1997 – four years, two months after she had firstcome to my office, and nearly four and a half years since her diagnosis of recurrent disease in thechest and liver.Although she ultimately died, ZA far outlived the usual prognosis for breast cancer recurring inmultiple sites (in her case, the liver and bone) after a course of aggressive chemotherapy. After twoyears of good compliance on treatment, CT and bone scans confirmed resolution of her previouslywidespread disease. Thereafter, for any number of reasons – finances, the influence of localdoctors, her overconfidence – her adherence to the regimen fell off considerably. Nonetheless, thispatient’s significantly improved clinical status on therapy, the radiographic findings of tumorregression in the liver, and the long term survival indicate a significant response to treatment.Eichbaum et al studied a group of 350 women with breast cancer that had metastasized to theliver.4 The authors describe a median survival, regardless of the conventional treatment given, of14 months.CASE 29Patient FQ: A 9-Year Survivor of Breast CancerPatient FQ is a 57-year-old women who had been in generally excellent health when in October1997, her gynecologist detected a large right breast mass, subsequently described onmammography as a suspicious lesion approximately 5 X 4 cms in diameter. The patient wasreferred to a surgeon who noted dimpling in the mass, a sign of aggressive disease, and suggestedmastectomy followed by radiation and chemotherapy as his note reports:“I discussed the treatment options with the patient from lumpectomy and axillary node samplingwith postoperative radiation to modified radical mastectomy. We also discussed the probable needfor adjunctive therapy with radiation and/or chemotherapy. I think with the size of the patient’s629

lesion and its proximity to the nipple that a modified radical mastectomy will in all probability bethe best treatment for her lesion.”The patient, who was already quite familiar with my work, initially wanted to refuse allconventional approaches and begin my treatment. When she called our office wishing to make anappointment, we insisted she proceed at least with surgery. So, in December 1997 she underwent alumpectomy and axillary node sampling. The pathology report describes a “4.09 x 3.0 x 3.0 tumormass,” consistent with moderately differentiated infiltrating tubulolobular carcinoma. The marginsappeared tumor free, but cancer had invaded two of nine sampled nodes.Other than a clear preoperative chest x-ray, no other radiographic studies were pursued. Hersurgeon however, insisted she consult with an oncologist and proceed with both radiation to thechest and chemotherapy. His notes state:“I have reinforced the need for the patient to see an oncologist as soon as possible and proceed onwith chemotherapy and radiation therapy as appropriate following her oncologic evaluation."FQ, having already decided to proceed only with my treatment, never did meet with the localoncologist. When we first met in my office in January 1998, she insisted she would not submit tochemotherapy. Subsequently, she proved to be a very determined and compliant patient and today,nine years later she follows a modified nutritional protocol, enjoys excellent health and leads a fulland productive life. In all this time, she has remained cancer free.I thought I would include this case for several reasons. Though she had no evidence of activedisease at the time she started with me, her large tumor and involvement in two lymph nodesportends for a poor prognosis long term. The standard treatment for such node positive disease hasbeen for more than twenty years, aggressive “adjuvant chemotherapy” after surgery. Suchtreatment, as the studies going back 30 years show, offers an improvement in disease free survivalcompared to surgery of some 10-15% – not an extraordinary advantage, but a mathematicallysignificant one nonetheless. Today, oncologists invariably add intensive radiation to the chest wallas well, and if the tumor is estrogen receptor positive, long term hormonal blockade.CASE 30Patient JK: A 16-Year Survivor of Uterine (Endometrial) CancerPatient JK is a 62 year-old women who had been in good health when in the fall of 1990, sherequired hospitalization for two episodes of deep venous thrombosis. She was placed on Coumadin,but shortly thereafter suffered an episode of severe vaginal hemorrhage. When the bleedingpersisted, in December 1990 she underwent a D&C, which revealed endometrial carcinoma. Aftera CT scan in January 1991 showed extensive abdominal and pelvic lymphadenopathy, sheunderwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy.The pathology report describes endometrial adenocarcinoma with areas of squamousdifferentiation, high nuclear grade (FIGO grade III), and papillary serous carcinoma, one of themost lethal of uterine malignancies. The tumor had spread to the left ovary, obliterating thefimbriated end of the left Fallopian tube. Biopsies of the peritoneal cul de sac as well as the rectalserosa confirmed metastatic disease, and due to the extent of metastasis, her doctors warned of avery poor prognosis.Postoperatively, JK met with a radiation oncologist who insisted treatment begin at once. Beforeagreeing to any therapy, JK decided to consult with a second oncologist in a Southern tertiary carecenter. Once again, radiation was aggressively pushed as essential to delay spread of heraggressive disease. However, JK decided to refuse all orthodox treatments, instead choosing tomedicate herself with a variety of nutritional supplements including high dose vitamin C and redclover tea.An abdominal MRI in March 1991 showed a “decrease in degree of periaortic lymphadenopathy630

with persistent evidence of matted lymph nodes…” Pelvic MRI documented “decrease in the degreeof diffuse pelvic lympadenopathy although there is persistent evidence of pelvic mass lesion mostnotable in the left hemipelvis. There is evidence of surgical defect presumably from previoushysterectomy…” So with surgery, there had been improvement, though clearly extensive diseaseremained.About that time, after learning of our work, JK decided to pursue my therapy. When first evaluatedin my office in April 1991, she reported persistent fatigue, a substantial recent weight loss of 15 lbs,“terrible night sweats,” and poor sleep.JK subsequently followed her regimen with great determination. Seven months later, in December1991, repeat MRI’s showed no change in the periaortic lymphadenopathy as compared with thestudy of March 1991, but significant regression of the pelvic adenopathy and the pelvic mass in theleft hemipelvis. The official report states:“Compared to the study of 3---91, there is continued improvement with near complete resolution ofpreviously seen pelvic lymphadenopathy. Currently, there is no appreciable residual mass lesionpresent within the left hemipelvis….”Thereafter, JK continued her nutritional program diligently, with reported improvement in hergeneral health. MRI studies of the abdomen and pelvis in January 1993, after she had completedsome 20 months on therapy, indicated that the previously noted extensive disease had completelyresolved. The pelvic scan revealed “There is no identified pelvic lymphadenopathy.” The officialreport of the abdominal MRI states “There is no evidence of significant periaortic or periportallymphadenopathy.”MRI studies completed 14 months later, in March 1994 confirmed “There is no distinct evidence ofmetastatic or recurrent disease.”JK followed her regimen faithfully until early 1997, when I last had formal contact with her. At thattime, six years from her diagnosis of metastatic aggressive histology endometrial cancer, sheremained disease free and generally in good health. She subsequently continued her therapy in areduced way, and at last report, now nearly 16 years from diagnosis, is alive and apparently doingwell.This case is straightforward: the patient was diagnosed with extensive, aggressive histology uterinecancer, including papillary serous, one of the most deadly subtypes. The surgeon could not exciseall the visible cancer, as MRI studies after surgery documented. She then experienced completeregression of her advanced disease while following her nutritional program, and remains alive 16years later.631

Allegated 23: Dott. WaisbrenAbout the Waisbren ClinicThe Waisbren Clinic was established in Milwaukee in 1951. Hereempathetic, traditional and investigative internal medicine has beenpracticed ever since. The need for our investigative studiessurfaced among our patients and those seen in our teachingactivities at Marquette Medical School and the Medical College ofWisconsin.The guiding principles of this clinic are: We first listen carefully to the patient on a one to one basisin the privacy of the physician's office; we then ask them how they think we can help them; and wepoint out to patients who have been told there is nothing to do that there is always something to doand that we will search for it.We have described the practice of the Waisbren Clinic as that of "investigative internal medicine".We base this on the premise that difficult and unusual cases may represent "experiments of nature".The intense study of these often reveals information of general interest.In this vein, we have been able to discover and report some important findings. They include:1) Gram negative shock2) Deafness due to aminoglycosides3) Platelet destruction due to ristocetin4) Potentiation of antibiotics by gamma globulin5) The utility of multiple antibiotics in severe burns6) Human lymphocyte-tumor cell interaction (see picture)7) The probable efficacy of combined immunotherapy in cancer.8) Some people with ALS have elevated Lyme disease antibody titers.9) Swine flu vaccine and hepatitis B vaccine were associated with autoimmune complications.Currently, the clinic focuses on both the practice of internal medicine and the diagnosis andtreatment of problem diseases.Further information regarding the above subjects can be found in our publications, which areavailable if you email waisbrenclinic@ameritech.net.About Dr. WaisbrenBurton A. Waisbren, Sr., M.D. is a native Milwaukean who received his B.S. and M.D. degreesfrom the University of Wisconsin Medical School in Madison, Wisconsin. He served his internshipat the Harvard Service at Boston City Hospital. His military service was at the Navy MedicalResearch Institute, Bethesda, Maryland and the Biological Warfare Center, Camp Dietrick,Maryland. His residency and fellowship was served at the University of Minnesota Hospitals wherehe was an instructor in the medical school. He received a master's degree in bacterial genetics fromthe University of Minnesota in 1951. He moved to Milwaukee, his hometown, in 1951 and632

established a private practice in internal medicine, infectious disease and immunology. At that time,he also headed the infectious disease control unit at the Milwaukee County Hospital. From 1951 to1969, he was the director of the infectious disease division of first the Marquette Medical Schooland then the Medical College of Wisconsin. During that time, he was appointed associate clinicalprofessor of medicine. He was the medical director of the St. Mary's Hospital Burn Center from1962 to 1982. He has directed a cancer immunotherapy clinic in Milwaukee since 1973. He haspublished numerous articles in the peer reviewed medical literature and has authored books onsystematic methods of critical care and on medical emergencies.Dr. Waisbren is board certified by the American Board of Internal Medicine and also is a fellow ofthe American College of Physicians and the Infectious Disease Society of America. He is afounding member of the Infectious Disease Society of America, the American Burn Association,and the Critical Care Society of America.Immunotherapy for cancer which includes: Coley's vaccine, mixed bacterial vaccine, transferfactor, BCG, and lymphoblastoid lymphocytes.A scientific essay regarding a 25-year experience in the treatment of cancer with multipleimmunotherapy modalities.http://www.waisbrenclinic.com/artinfo.htmlhttp://www.waisbrenclinic.com/chronic-lyme-disease-case-reports.htmlThree anecdotal case reports regarding chronic lyme disease with a hypothesis that mightexplain how they came about *IntroductionProfessor Teddo Adderatti of the medical school in Bolgna Italy introduced case reports as amedical teaching tool in the mid-thirteenth century. Although they have fallen into some disreputedue to present feelings about the lack of importance of anecdotal evidence, they still can be seen inmany prestigious medical journals.The Jewish King Solomon who lived in the tenth century B.C. is credited by some for the biblicalquote “there is nothing new under the sun-what happens will happen again.” It is in these contextsthese three reports and a hypothesis that might explain them is being presented.Case One: The patient is a 63-year old retired male science teacher who spent his summers in afarm in Wisconsin that was in an area known to be infested with deer tics. At age 55 he developeda progressive syndrome that consisted of generalized muscle cramping and spasm. Over the next 4years these symptoms grew to include severe fatigue, difficulty in concentration, neuropathicnumbness and pain both of this feet and severe testicular pain. Low body temperature, generalizedfasciculations over his torso and extremities and an unexplained sudden central retinal veinocclusion in his left eye.During the ensuing six years after the onset of the syndrome all of the symptoms graduallyincreased until they came to the point that he could no longer function. Visits to many physiciansand specialty clinics failed to provide an explanation for this clinical picture.633

He searched the web and came to the conclusion that he might have Lyme disease. He consultedme in this regard in April of 2005 and I agreed that this was a possibility. HE agreed to mysuggestion that we try an empirical course of intravenous Ceftriaxone to see if it helped him. Priorto the antibiotic regimen, the patient was tested for Lyme disease by Western Blot test performed byIgenex Laboratories. These results were suggestive but not conclusive for the presence of Lymedisease. He also underwent an experimental Lyme test performed by Bowen Labs of Florida. Thistest strongly indicated Lyme infection.Accordingly, he was given an eight-week course of intravenous Ceftriaxone and Flagyl. The Flagylwas given to help his gastrointestinal tract tolerate the Ceftriaxone and for the theoretical conceptthat Flagyl might kill cystic forms of Borrelia. The Flagyl was discontinued when it seemed toincrease the neuropathic pain and numbness in his feet and legs. He suffered no Herxheimerreaction but made gradual improvement during the initial program. After the Ceftriaxone he wasmaintained on 3000 mg of oral penicillin daily for three weeks followed by 50 days of 200 mg ofDiflucan. This regimen of penicillin followed by Diflucan was repeated one additional time. Hisimprovement continued and within weeks he was essentially asymptomatic. The oral antibiotictreatment was complete din January of 2006. Additionally, in January of 2007 Mr. C. was put on adaily course of low dose Naltrexone (4.5 mg daily). Mr. C. reported that this greatly decreased theoccasional return of fatigue, depression and testicular and neuropathic pain. In December 2007 hefelt well and was functioning normally.Case 2: This highly intelligent and active registered nurse was 50 years old when in 19922 shesuffered a tic bite that was followed by a bull’s eye rash and a positive blood test for Lyme disease.She was treated for 10 days with doxycycline. She as told that this cured her Lyme disease. Shelived in Minnesota in an area known to have deer tics.Several months after the 1992 incident she developed a progressive symptom complex that includedsevere fatigue, muscle weakness and episodes that suggested to some narcolepsy and to others amysterious virus. During the ensuing ten years all symptoms increased and the physicians sheconsulted could not find an explanation for them.She saw me in 2002 with a chief complain of severe debilitating chronic fatigue. She had come tothe conclusion that she had this syndrome after she looked it up on the Internet and made a selfdiagnosisof Lyme disease. She had never mentioned the fact that she had had Lyme disease to herdoctors nor had she ever been asked about this disease. She had accepted the original opinion thatshe had been cured. After hearing her entire story, I concluded that while indeed she waschronically fatigued that something else was wrong.Knowing that she came from Minnesota in an area in which deer tics were present, my first questionto her was whether she had been exposed to tic bites. She told me about her case of Lyme diseasein 1992. After the initial preliminary tests were done and were normal I suggested to her that shemight have chronic Lyme disease. I suggested an empirical treatment program tailored to not onlytreat the Lyme disease but to treat her chronic fatigue in spite of the fact, that all tests for Lymedisease were negative.I suggested this because she shared with me “she had reached the limit of her endurance’. Theprogram consisted of the following:1. Ceftriaxone, 4 grams given intravenously through a pic line for 4 weeks2. Flagyl, 500 mgs daily to be taken by mouth. This was to help her tolerate the Ceftriaxone bowelwiseand also to treat the theoretical cystic forms of Borellia which some think will be effective inthis regard634

3. To treat her fatigue, Gamma Globulin 4cc i.m., twice a week for 4 weeks, to perhaps providesome blocking antibodies that would inhibit autoimmunity4. Isoprimosine, 50 mgs by mouth four times a day to stimulate T-cells5. Valtrex, 1000 mgs, twice a day by mouth to treat the Epstein Barr virus which I felt might beinvolved in her disease (see the hypothesis that follows the case reports)When there seemed to be a marked salutatory response of her entire symptom complex wecontinued the oral and intra muscular elements on an intermittent basis. There was marked gradualimprovement in all her symptom complex starting after the intravenous Ceftriaxone. Thiscontinued as we tapered the medication over the next four years. A complete examination inJanuary 2008 revealed that she was symptom-free and living a very busy productive life. Thisconsisted of taking care of her three children and running programs dedicated to the care of fosterchildren who had developmental problems.Case 3-AR; A case of chronic Lyme disease that mimicked multiple sclerosisThis case is another incidence of the truth of the biblical saying “there is nothing new underthe sun. What happens once will happen again.” Soon after I had finished bringing up to date thiswebsite a young physical therapist who had two small children presented her self for anexamination with the following story: I will present it in her own words, modifying only herfeelings about the delay in diagnosis and treatment. “I am a physical therapist. I know my body. Iwas healthy and fit until June 9, 2007 when I attended an outdoor party in Richmond, Illinois. Aday after the party, I noticed a red, circular rash about the size of a quarter on my lower rightabdomen. I knew immediately this bite was different than the typical bug bit—it was angrierlooking, and had a distinctly defined center. I immediately thought of Lyme disease. But everyone Iknew who lived in Richmond and all the medical professionals I knew, said no way. It couldn’t beLyme disease. They had never heart of it in Richmond, or Illinois for that matter. So I put it out ofmy mind.About four days later I suddenly felt very sick, faint and out of it. I had several bouts ofdiarrhea. My husband rushed to my side and took me to see the obstetrician who had delivered mysecond baby four weeks before. He said the symptoms were probably nothing or blood poisoning.About the bite he said he had had one also on his arm, probably from a mosquito.The feeling of being sick remained so a week later I saw an internist. He said I absolutelydid not have Lyme disease because I hadn’t seen the tick and the tic would have ballooned up withblood to enormous size. He also said that there was no Lyme disease in our area. He did notadvise treatment or studies. Then the muscle twitches began along with the strange travelingparesthesia. Then I noted electric type currents through my extremities and migrating joint pain.I continued to seek help and saw two other physicians in my area. They empiricallyprescribed antibiotics but said that the blood tests that they had run were negative so I could nothave Lyme disease. My symptoms continued and got worse, and then a brain fog set in. I couldn’tseem to concentrate. I felt mentally weighed down and fuzzy headed and mentally depressed andfrightened.I sought another internist who when my Lyme tests came back negative told me I couldn’thave Lyme disease and that I should discontinue the antibiotics. My symptoms remained. I beganwondering if it’s not Lyme, then what is it? A pinched nerve, carpal tunnel, fibromyalgia, someprogressive neurological disease? I was researching and researching and still, the only thing thatmade any sense was Lyme. Eventually, and logically, my mind wandered towards MS. By thispoint, I had developed a positive l’hermittes sign. I referred myself to a chiropractor. I saw him 3times and he was stumped. But we did discuss the possible justification for an MRI. So I didn’tappear to be a hypochondriac, I referred myself to a neurologist at another one of Chicago’spremier hospitals prior to requesting any MRI. This neurologist, I could tell somewhat reluctantly635

gave me the referral. The MRIs revealed the cause of many of my symptoms-4 white lesions, 2inthe brain and 2 in the cord. He then referred me for a lumbar puncture, which came back positivefor antibodies to “something” and 2 oligoclonal bands. He diagnosed me with, most likely,relapsing-remitting MS. My “Lyme tests” were again negative. My family and I were crushed. Wediscussed beginning MS drugs. I soon thereafter had my first full-blown neurological event,partially brought on by the stress of this nightmare..diffuse numbness and muscle spasms, andended up in the ER, and then in the hospital for a night.The patient continued her search for help and more consideration of the possibility of her findingsbeing due to Lyme disease and through this website decided to come to see me about her problems.Her history, the white lesions on her MRI, the picture of her tic bite that she showed me, herhyperreflexia, paresthesia, ataxia and absent abdominal reflexes convinced me that she had Lymedisease masquerading as multiple sclerosis. An empirical course of anti Lyme disease therapy wasstarted through a “pic line.” It consisted of a six week course 4 grams of intravenous Ceftriaxoneand flagyl, 500 mgs given twice a day by mouth. She is being continued on oral doxycycline anderythromycin. Blood tests done at her first visit did come back suspicious for Lyme disease. Theywere done by Quest laboratories and confirmed by Bowen Laboratories. She also had antibodiesagainst Bartonella Henselae and Bartonella Quintana which confirmed exposure to tics. Fourmonths after the completion of the intravenous Ceftriaxone she describes her situation as follows:“I complete a 6 week course of IV antibiotics, coupled with some oral medications and amnow in my fourth month of treatment for chronic Lyme disease. I feel immeasurably better. Mybrain fog has completely cleared. I’m not tripping over my words or losing my train of thoughtanymore. MY paresthesias and muscle twitches are few and far between. My energy level is up.All in all, I feel almost back to normal and most definitely vindicated. And I’m now on a mission toeducate others about this often misdiagnosed and mistreated disease. This is a “silent epidemic”,as many like to call it. Had I listened to the highly regarded and overly confident neurologist whodiagnosed me with MS I would now be much sicker, getting precisely the wrong treatment, andheaded for more debility.Comment: Of course a few anecdotes do not establish anything but each case of an unusual naturethat presents itself to an inquiring physician should not be ignored. The third case buttresses myopinion that is outlined on this website that cases of MS-like nature that appear after tic exposuredeserve an empirical course of Lyme treatment. Finally, it is to be noted that each of these threecases was self-referred after they had studied the Internet. They indicate that we all should listencarefully to patients who come in with reams of Internet material. Some, but certainly not all, mayhave been able to arrive at correct diagnoses.A Hypothesis which might explain what happened to these three patients.This hypothesis is based on the work of Westall and Root-Bernstein.* They proposed inthe mid 1980s that an autoimmune disease can occur when a host is exposed to two chemicallycomplementary antigens one of which exhibits molecular mimicry with the host tissues. Inaddition, the host must have a certain HLA pattern and an immunological adjunct must be present.They named their syndrome “multiple antigenic mediated autoimmunity”, the MAMA syndrome.Root-Bernstein proposed that this syndrome occurred in some AIDS patients because they wereexposed to multiple viral and bacterial antigens. This exposure occurred because of their T-cellproblems. I propose that the three patients described developed a MAMA syndrome because theirBorrellia antigens were chemically complementary to the Epstein Barr virus to which they had hadevidence of being exposed. That Epstein Barr virus shows molecular mimicry with human tissuewas shown by Root-Bernstein. The immunologic adjunct necessary for this syndrome wasprovided by indigenous myramyl peptides produced by the host’s indigenous mononuclear cells.Finally, the initial clones stimulated by the MAMA syndrome became rogue clones and attackedtissues in addition to those involved in their being developed.636

Discussion and conclusions: Certainly these anecdotal case reports do not prove anything. Theyare presented because of the large numbers of individuals who appear to be struggling with similarsyndromes after they have been exposed to tic bites. This number seems to reveal itself when onetakes even a cursory look at websites and chat rooms on the Internet.*See the discussion about this syndrome and references in the section in this website on MSfollowing Hepatitis B vaccinationSurely all of these concerned suffering individuals are not suffering from “extraordinary populardelusions and madness of crowds, so brilliantly described by Charles Makay in 1841.It is my hope that the hypothesis presented here will stimulate interest in methods to helpunfortunate individuals who suffer from chronic Lyme disease. It seems that the proceduresdescribed here may help some of these but if as I propose chronic Lyme disease has an autoimmuneaspect attempts to treat this aspect empirically may be in order.It would appear to me that intense consideration should be given to the possibility thatmultiple antigenic exposure can cause autoimmune disease because of the multitude ofvaccines that are now being introduced into general use. The experiments that can be done toprove or disprove this hypothesis are presented later on pages on this website where weexplain autoimmunity that occurs after vaccintations in a similar manner.Read More About Chronic Lyme DiseaseThe Management of Chronic Lyme diseaseTreatment of Amyotrophic Lateral Sclerosis and Multiple Sclerosis with Anti-Lyme DiseaseAntibiotics with AntibioticsView our Notice of Privacy PracticesDISCLAIMERTHIS WEBSITE DOES NOT PROVIDE MEDICAL ADVICE. The contents of the WaisbrenClinic website, such as text, graphics, images, and other material contained on the Waisbren Clinicwebsite ("Content") are for informational purposes only. The Content is not intended to be asubstitute for professional medical advice, diagnosis, or treatment. Always seek the advice of yourphysician or other qualified health provider with any questions you may have regarding a medicalcondition. Never disregard professional medical advice or delay in seeking it because of somethingyou have read on the Waisbren Clinic website! If you think you may have a medical emergency,call your doctor or 911 immediately. Reliance on any information provided by the Waisbren Clinic,Waisbren Clinic employees, or other visitors to the website is solely at your own risk.637

ALLEGATED 24Fifteen clinical cases of the Kroiss Center (Vienna, Austria)The Kroiss-Cancer-Center for Alternative Cancer Therapy run by Dr. Thomas Kroiss in Vienna, Austria isespecially known for treating breast cancer, cancer of lung, colon/rectum, prostate, brain tumor, leukemia, livermetastases, bone metastases, and ovarial tumors, using Their website is http://www.kroisscancercenter.com/ andthey can be reached by phone at 43-1-982 57 67 or by fax: 43-1-982 69 92.Examples of successful therapies:Here we present therapy results and successes to show that even very progressed cancer cases canbe cured. Usually we make individual therapy protocols that consist of a number of therapies - justto make sure. Yet the following therapy results and successes have been produced by one singletherapy of those. We show you those because of the many years of experience with this.Anyway: Please do not wait until such a progressed stage. The earlier you start with the therapy thebetter your chances.(Please let us remind you that this treatment modality is most promising when at its beginning thepatient's expected time of survival is at least six months. The following examples, however, refer tomore seriously afflicted patients. They are taken from a textbook of the 1930s and 1950s. Lastedited in 1980, it is now out of print; some of the medical terms used in the original descriptionshave been replaced with more colloquial equivalents)Case 1: Inoperable tumor of left half of the brain. Patient was in very poor state, could not speak,did not respond, was totally incontinent (urine and feces). X-ray showed an enormous enlargementof the right ventricle of the brain, the left ventricle could not be visualized. Therapy was begun.Three months later, patient had much improved, half a year later patient had no symptomswhatsoever. Continued to live in good state for many years.Case 2: An angiography was performed on a patient admitted to the neurological universityhospital. It revealed a constricting process reaching from the cerebral cortex down into the brainstem. Patient suffered from jacksonian-type seizures every day. Radiation therapy failed entirely.Following radiation, patient even had up to 17 seizures a day. It was difficult for patient to walk ortalk, eyeballs were bulging. Treatment started in 1971. After six weeks, patient was withoutseizures, has remained in good state until now (1980).Case 3: Ovarian carcinoma, was diagnosed by histological findings, inoperable, had grown into therectum. X-ray confirmed intestinal stenosis. Patient was terminally ill, required morphine four timesa day. Treatment began in 1953. After six months, patient was symptom-free. Treatment wascontinued by her general practitioner. Treatment was discontinued in 1965. Patient was still alive in1977.Case 4: Patient diagnosed with cancer-induced intestinal stenosis in 1956. Improved under therapy,but then withdrew. A year later blood was found in the urine. Bladder had cauliflower-like tumor(x-ray). After regular treatment hardly any complaints half a year later (clear x-rays of 1975 provethis point). Patient was still alive in 1980 at age 87 (only had some problems with hip, but wasotherwise in a good state).Case 5:An 18-year-old young man was operated on by a brain surgeon in 1933. A largeglioblastoma (i.e. a malignant brain tumor, generally considered to be incurable) of the cerebellumwas found, which could not be excised. The patient was about to die. Because of the increasing638

intracranial pressure, the patient underwent a trepanation (i.e. a hole had to be drilled into the skullto alleviate the pressure). When the patient started treatment, he was dying. He could neither standup, nor sit down, was confined to bed, vomited all the time and was only able to babble. He wasemaciated and had lost his sense of balance. During the first therapy sessions, he had to vomit everytime. This improved only gradually within half a year. Only then was the patient responsive andbetter able to retain some food. Treatment was continued daily, and the patient's state improvedvery slowly, he gained weight (10 kg). After one and a half years he had gained 20 kg. He was ableto resume his former job. He started traveling and had almost no symptoms, except for somebalance disorder which forced him to walk with a cane. Also, there was a minor speech disorder.This was due to the fact that prior to treatment major portions of the cerebellum had been destroyed.The patient was 18 years old when treatment began. He died at age 59.Case 6: In 1947, a 46-year-old patient had a tumor on the right ovary, which was surgicallyremoved. In 1952, a carcinoma developed on the uterus. A sample taken revealed this to be a"papillary adenocarcinoma". Since this tumor was inoperable, the patient underwent radiation, butto no avail. In March 1953, doctors diagnosed that the tumor had grown into the rectum. On 1August 1953, the tumor was seen to have grown into the other side of the intestines as well. Thepatient lost weight and was under severe pain. In October of the same year, her state was hopeless.Her husband was informed accordingly. She was given morphine, and her stool was thin andhemorrhagic. Therapy was started on this bedridden patient. Six weeks into therapy, she did nolonger lose weight, her weight remained the same for two months, whereupon she started to gainweight ever so slowly. After eight weeks she did not need any pain killers any more. After twomonths, it was possible to enter the previously too contracted rectum with one finger. Four weekslater you could even introduce a rectoscope to see that the rectal wall was covered in tumor massesfor up to 10 cm (from bottom). The patient remained without symptoms until 1970. Hergynecological findings had improved as early as in 1960. Since then no more treatment.Case 7: On 17 May 1960, the patient underwent an operation to remove a colon carcinoma. Thiswas an orange-size, mucous-producing cylindro-adenoma. At the base of the intestines severalbean-size hard glands were palpable. Examinations revealed that those were the metastases of agelatinous cancer. Treatment began at the end of September. Patient was in very good state until1974. No further follow-up.Case 8: A 27-year-old patient was diagnosed with thyroid carcinoma in 1967, which was surgicallyremoved in August 1968. She then underwent 28 cobalt radiation sessions (i.e. radiation therapy)without success. Roughly one year later, she had breathing difficulties. Laminograms of the lungsshowed extensive round shadows around the two lung roots, which grew rapidly. Treatment startedon 30 September 1968. The following year, no shadows could be detected any more. The patienthad gained weight. The hard lumps, which had previously been palpable in the right supraclavicularfossa, went back. The patient's findings improved. Since then she has felt absolutely well.Case 9: The 60-year-old farmer Z. was a similar story. He came for consultation because of laboredbreathing, blood in his sputum and considerable weight loss. The radiologist found a roughly gooseegg-sized shadow in the right lung close to the hilar region. The patient seemed to be inoperable.Under our therapy, the shadow became smaller and smaller and was hardly discernible after sixmonths. The patient had gained 18 kg and was able to work in his fields. When he moved to anotherplace in 1952, treatment had to be discontinued. A year later, the tumor had started to grow again. Abronchoscopic examination showed it to be a malignant carcinoma (cancer). This relapse resulted inthe patient's death. (This example shows that patients should not completely withdraw from such atherapy.)639

Case 10: The 60-year-old farmer L.J. came for consultation in 1952. He suffered from laboredrespiration, and his skin was bluish, a condition that had developed over the past months. He wascoughing, and there was blood in his sputum. He was unable to negotiate a five-step staircasewithout help, and even when assisted his respiration was extremely labored. X-ray findings of 10September 1952: diaphragms with indistinct margins on both sides; in the right lower area smallcloudy shadow containing several softer round shades; the right root of the lung was swollen andprotruding, the left root was widened; in the right medium and lower part of the lung there was aninhomogeneous mucous cloudiness containing several cherry-size round shadows; in the first upperpart of the lung, close to the root and below the clavicle between the first and second anterior ribs,there were two cherry-size round shadows. Diagnosis: cancer-filled lung roots, atelectasis on theleft and cherry-size metastases in the right lower part and in the left middle, lower and upper part.No histological examination was performed to clarify the nature of the shadows seen, but severaleminent radiologists confirmed that they could only refer to cancerous growths, probablymetastases of some undetected primary tumor. Whatever their nature, it is worth noting that thoseshadows fully disappeared within five years of treatment. In fact, the patient was almost withoutcomplaints after a mere six months and could resume his work as a farmer. Whenever treatmentwas discontinued for several weeks in the first three years, his breathing difficulties re-occurred andonly disappeared after two to three weeks of resumed therapy. Patient lived for another ten years ingood state and died in an accident.Case 11: Also in the 50-year-old physician, Dr. C., discontinuation of successful treatment led to arelapse. He arrived with mucous effusion in the lung area. A bronchial carcinoma was diagnosed bybronchographic and bronchoscopic examinations performed in the surgical ward of a universityhospital. The patient was in a very poor condition. He responded to our therapy within a few weeks,i.e. his status improved and the effusion disappeared against all expectations, as up until then wehad not been successful in cancerous processes involving the accumulation of fluid. He even gainedenough strength to be able to resume working in his practice and driving his car over greaterdistances. After six months, he was absolutely symptom-free. Despite repeated warnings hewithdrew from therapy. Three months later cancer reoccurred, as predicted, and led to the patient'sdeathCase 12: Heinrich He., born in 1893, farmer and innkeeper. In July 1956, sudden constipation,tearing pain in the hypogastric region, intestinal bleeding. ESR 68/89, delayed evacuation of thelarge intestines under x-ray. Impossible to fill one section with contrast medium. Treatment startedin May 1958, whereupon general condition and bowel movement improved. In September 1958,renewed contrast radiograph of the bowel passage which showed that there was still an area in thesigmoid colon that could not be fully filled with the contrast medium; there was no visualizationand an irregular margin of the defect. Incomplete opacification also in the upper part of thedescending colon. Treatment was continued, and towards the end of 1959 the patient was symptomfree.Treatment was discontinued because the patient's health fund refused any furtherreimbursement of treatment-related travel costs. In September 1960, he was again afflicted. Inaddition, he had trouble with his bladder, cramps in the bladder region, intermittent micturition,flakes and blood in his urine. A cystoscopy revealed polypous, villous growths in the bladder. Afollow-up examination performed in the surgical ward confirmed these findings. Rectoscope couldnot enter more than 15 cm. Clinical diagnosis: carcinoma (cancer) in the colon. Operation wasrecommended but refused by patient in view of the high risk. in March 1961, cystocscopy: aroundthe right ureteral orifice cauliflower-like soft, slightly hemorrhaging masses without structure,which filled the whole upper side of the bladder. Treatment was resumed in March 1961,whereupon symptoms improved within eight weeks. Patient was then able to pass water withoutdifficulty, he took mild laxatives to have regular bowel movement. Towards the end of November1962, the patient was symptom-free and able to work again. No pathological changes could be640

detected in an x-ray performed in 1974 on his intestines. This good status could be maintained -except for an inflammation of the hip joint - to this very day (1980). Patient is still alive.Case 13: A patient, born on 24 September 1920, noticed intestinal bleeding in spring 1975. He lostmuch weight. In 1976, he was diagnosed with rectal cancer, which greatly constricted the lumen.The patient underwent surgery on 24 March 1976 and was given a preternatural anus. A biopsyshowed that he had an adenocarcinoma. Also a second surgical intervention on 14 April 1976 didnot succeed in removing the tumor. It adhered irremovably to its environment. The left and rightlobes of the liver had hard nodes, the artery was surrounded by many smaller nodules. The tumorreached down to the hypogastric region, the lesser pelvis was not accessible to the palpating hand.On 11 May 1976, the patient had lost 12 kg. Nothing but some thin broth left the anal orifice.Within 4 cm, hard nodes all around the rectum. Therapy started on 11 May 1976, first at thehospital and then by the patient's general practitioner. Already on 18 May 1976, he had gainedweight (85 kg versus 83 kg), and on 16 July he had 89 kg. Very good condition, anus evacuatednormal stool, only the fingertips could still palpate one small nodule. On 29 June 1977 the patient'sgeneral practitioner reported: general condition is very good, patient is fit, can drive larger distanceshimself with his own car. The only remaining symptoms are winds and occasional constipation.Since then no further news.Case 14: That "cancer of the lymph nodes" also responds to this treatment is illustrated by thefollowing case: a young woman, born on 13 October 1937, noticed in 1960 greatly enlarged glandson the neck, which first became smaller under red light irradiation. Following a biopsy, she wasdiagnosed with Hodgkin's disease and given deep x-ray treatment and Endoxane injections(chemotherapy). On 13 June 1962, several soft, not clearly defined lymph nodes were detected onthe right side of the neck, while the left side showed a scar from the previous biopsy. The spleenwas no longer palpable. The erythrocyte sedimentation rate (ESR) was 21/42, i.e. the blood picturewas tell-tale. Regular treatment began in June 1962. Since then, no more enlarged glands. Thepatient married and gave birth to a healthy child. She feels well. Her ESR was 8/25 last time, herhematology measures were normal.Case 15: Even in very severe cases, it is sometimes possible to help: the 76-year-old M. El. washospitalized on 19 June 1958. He was emaciated and in a very poor state. There was blood in hisfeces, he suffered from severe anemia with 1.8 million erythrocytes, he had to be given bloodtransfusions. Under our therapy his general condition and hematology measures graduallyimproved. It took him eight weeks to recover enough to be able to undergo an x-ray examination. Itrevealed a large recess on the inner curve of the stomach, which could still be seen (though muchsmaller) in an examination one year later. The patient's condition improved so much that he wasagain able to care for himself and even go on some errands. Being symptom-free, he did not returnfor treatment after one year. Two years later he died at the age of 79.641

Thousand Plants against Cancer without Chemo-2010(1)

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