Skip to content
Licensed Unlicensed Requires Authentication Published by De Gruyter June 12, 2019

Extractives and biological activities of Lamiaceae species growing in Uzbekistan

  • Nilufar Z. Mamadalieva EMAIL logo , Davlat Kh. Akramov , Stefan Böhmdorfer , Shahnoz S. Azimova and Thomas Rosenau
From the journal Holzforschung

Abstract

Plants of the Lamiaceae family are important ornamental, medicinal and aromatic plants, with many of them producing essential oils that are used in traditional and modern medicine as well as in the pharmaceutical industry. This review summarizes research on selected Lamiaceae species from the Uzbekistan flora with regard to their chemical constituents and biological activity. These plants contain many bioactive compounds, such as ecdysteroids, iridoids, flavonoids, terpenoids, phenolics and alkaloids, exhibiting different antibacterial, antifungal, cytotoxic and antioxidant activities. The botanical description, taxonomy, habitat and ethnopharmacology of the investigated Lamiaceae species that have been used in Uzbek traditional medicine are presented as well, including the local names.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

References

Abdukadirov, I.T., Khodzhaeva, M.A., Turakhozhaev, M.T., Mamatkhanov, A.U. (2004) Carbohydrates from Ajuga turkestanica. Chem. Nat. Compd. 40:85–86.10.1023/B:CONC.0000025475.31616.47Search in Google Scholar

Adylov, T.A., Machmedov, A.M. (1987) Phlomoides Moench. Conspectus Florae Asiae Mediae. T.A., A. Izdatel’stvo Akademii Nauk SSSR, Tashkent. pp. 82–107.Search in Google Scholar

Agostini, F., Santos, C.A., Rossato, M., Márcia, R.P., Paula, L.S., Serafini, L.A., Molon, R., Patrick, M. (2009) Essential oil yield and composition of Lamiaceae species growing in southern Brazil. Braz. Arch. Biol. Technol. 52:473–478.10.1590/S1516-89132009000200026Search in Google Scholar

Ali, T.N., Demirci, B., Blythe, E.K., Baser, KH.C., Khan, I.A. (2016) Chemical composition and biological activity of essential oils from four Nepeta species and hybrids against Aedes aegypti (L.) (Diptera: Culicidae). Rec. Nat. Prod. 10:137–147.Search in Google Scholar

Asilbekova, D.T., Gusakova, S.D., Umarov, A.U. (1983) Neutral lipids of the seeds of Phlomis oreophilla and Ph. regelii. Chem. Nat. Compd. 19:525–529.10.1007/BF00576074Search in Google Scholar

Bhat, R.D., Moskovitz, G. (2009) Herbal medicinal teas from South Africa. Int. J. Exp. Bot. 78:67–73.Search in Google Scholar

Brahmi, F., Khodir, M., Mohamed, C., Pierre, D. (2017) Chemical composition and biological activities of Mentha species. In: Aromatic and Medicinal Plants – Back to Nature. El-Shemy, H.A. InTech. p. 296.Search in Google Scholar

Carović-Stanko, K., Marko, P., Grdiša, M., Pintar, J., Bedeković, D., Herak, Ć.M., Satovic, Z. (2016) Medicinal plants of the family Lamiaceae as functional foods – a review. Czech J. Food Sci. 34:377–390.10.17221/504/2015-CJFSSearch in Google Scholar

Cases, A., Pérez, B., Navarrete, P., Mora, E., Peña, B., Peluzzo, A., Calvo, R., Sánchez De Ron, D., Varela, F. (2009) Variability in the chemical composition of wild Thymus vulgaris L. Acta Hortic. 826:159–166.10.17660/ActaHortic.2009.826.22Search in Google Scholar

Cauffield, J.S., Forbes, H. (1999) Dietary supplements used in the treatment of depression, anxiety, and sleep disorders. Lippincotts Prim. Care Pract 3:290–304.Search in Google Scholar

Cheng, D.M., Yousef, G.G., Grace, M.H., Rogers, R.B., Gorelick-Feldman, J., Raskin, I., Lila, M.A. (2008) In vitro production of metabolism-enhancing phytoecdysteroids from Ajuga turkestanica. Plant Cell Tissue Organ Cult. 93:73–83.10.1007/s11240-008-9345-5Search in Google Scholar

De Pooter, H.L., Nicolai, B., De Buyck, L.F., Goetghebeur, P., Schamp, N.M. (1987) The essential oil of Nepeta nuda. Identification of a new nepetalactone diastereoisomer. Phytochemistry 26:2311–2314.10.1016/S0031-9422(00)84709-3Search in Google Scholar

Desbois, A.P., Smith, V.J. (2010) Antibacterial free fatty acids: activities, mechanisms of action and biotechnological potential. Appl. Microbiol. Biotechnol. 85:1629–1642.10.1007/s00253-009-2355-3Search in Google Scholar PubMed

Dzhumaev, Kh.K., Zenkevich, I.G., Tkachenko, K.G., Tsibui’skaya, I.A. (1990) Essential oils of the inflorescences and leaves of Ziziphora brevicalyx. Chem. Nat. Compd. 36:99–101.10.1007/BF00605220Search in Google Scholar

Eisenman, S.W., Zaurov, D.E., Struwe, L. Medicinal Plants of Central Asia: Uzbekistan and Kyrgyzstan. Springer, New York, USA, 2013.10.1007/978-1-4614-3912-7Search in Google Scholar

Erdtman, G. (1945) Pollen morphology and plant taxonomy. IV. Labiatae, Verbenaceae and Avicenniaceae. Sven. Bot. Tidskr. 39:277–285.Search in Google Scholar

Falcone, P., Speranza, B., Del Nobile, M.A., Corbo, M., Sinigaglia, M. (2005) A study on the antimicrobial activity of thymol intended as a natural preservative. J. Food Protect. 68:1664–1670.10.4315/0362-028X-68.8.1664Search in Google Scholar

Ganiev, Sh.G., Khamidkhodjaev, S., Djuharova, M.X., Saatov, Z. (1990) Ajuga turkestanica from Baysuntay (Baiyun mountain). Uzbek Biol. J. 30–32.Search in Google Scholar

Gintzburger, G. Rangelands of the Arid and Semi-Arid Zones in Uzbekistan. CIRAD, International Center for Agricultural Research in the Dry Areas, 2003.Search in Google Scholar

Gormez, A., Bozari, S., Yanmis, D., Gulluce, M., Agar, G., Sahin, F. (2013) Antibacterial activity and chemical composition of essential oil obtained from Nepeta nuda against phytopathogenic bacteria. J. Essent. Oil Res. 25:149–153.10.1080/10412905.2012.751060Search in Google Scholar

Grace, M.H., Diana, M.Ch., Raskin, I., Lila, M.A. (2008) Neo-clerodane diterpenes from Ajuga turkestanica. Phytochem. Lett. 1:81–84.10.1016/j.phytol.2008.03.004Search in Google Scholar PubMed PubMed Central

Guibout, L., Mamadalieva, N., Balducci, C., Girault, J-P., Lafont, R. (2015) The minor ecdysteroids from Ajuga turkestanica. Phytochem. Anal. 26:293–300.10.1002/pca.2563Search in Google Scholar PubMed

Gusakova, S.D., Umarov, A.U. (1972) The oils of some plants of the family Labiatae. Chem. Nat. Compd. 8:23–28.10.1007/BF00564429Search in Google Scholar

Harley, R.M., Atkins, S., Budantsev, A.L., Cantino, P.D., Conn, B.J., Grayer, R.J., Harley, M.M., de Kok, R.P.J., Krestovskaja, T.V., Morales, R., Paton, A.J., Ryding, P.O. (2004) Lamiales (except Acanthaceae including Avicenniaceae). In: Flowering Plants, Dicotyledons. Kadereit, J.W. Springer-Verlag: Berlin, Heidelberg. pp. 478.Search in Google Scholar

Huang, Z., Zhu, Z-X., Li, Y-T., Pang, D-R., Zheng, J., Zhang, Q., Zhao, Y-F., Ferreira, D., Zjawiony, J.K., Tu, P-F., Li, J. (2015) Anti-inflammatory labdane diterpenoids from Leonurus macranthus. J. Nat. Prod. 78:2276–2285.10.1021/acs.jnatprod.5b00635Search in Google Scholar PubMed

Ibragimov, M.H., Akmuradov, A., Khodjamberdiev, Z.D. (2015) Nekotorye endemichnye lekarstvennye rasteniya Koytendaga, primenyaemye v gastroentrologii [Some endemic medicinal plants of Koytendag used in gastroenterology]. Exp. Clin. Pharmacol. 117:90.Search in Google Scholar

Isaev, I.M., Agzamova, M.A., Isaev, M.I. (2011) Genkwanin and iridoid glycosides from Leonurus turkestanicus. Chem. Nat. Compd. 47:132.10.1007/s10600-011-9857-9Search in Google Scholar

Israili, Z.H., Lyoussi, B. (2009) Ethnopharmacology of the plants of genus Ajuga. Pakistan J. Pharm. Sci. 22:425–462.Search in Google Scholar

Kadereit, J.W. Flowering Plants. Dicotyledons: Lamiales (Except Acanthaceae Including Avicenniaceae). Springer-Verlag, New York, 2004.10.1007/978-3-642-18617-2Search in Google Scholar

Khalitova, Y.D., Syrov, V.N., Akhmedkhodjaeva, Kh.S., Mamatkhanov, A.U. (1998) Possible use of the extract of Ajuga turkestanica as a remedy contributing to lactation. Dokl. Akad. Nauk Respubliki Uzbekistan 35–38.Search in Google Scholar

Khodjimatov, K., Aprasidi, G.S., Khodjimatov, A.K. Wild Growing Medicinal Plants of Central Asia. Abu Ali ibn Sino, Tashkent, Uzbekistan, 1995.Search in Google Scholar

Kholmatov, Kh., Kosimov, A. Medicinal Plants. Ibn Sino, Tashkent, 1994.Search in Google Scholar

Kholmatov, Kh., Makhsumov, M. Medicinal Plants for Treating Colds. Ibn Sino, Tashkent, 1993.Search in Google Scholar

Klimek, B., Modnicki, D. (2005) Terpenoids and sterols from Nepeta cataria L. var. citriodora (Lamiaceae). Acta Poloniae Pharmaceutica 62:231–235.Search in Google Scholar

Kokkini, S., Karousou, R., Hanlidou, E. (2003) Herbs of the Labiatae. In: Encyclopedia of Food Science and Nutrition. Academic Press, Amsterdam, The Netherlands. pp. 3082–3090.10.1016/B0-12-227055-X/00593-9Search in Google Scholar

Kotenko, L.D., Yakubova, M.R., Mamatkhanov, A.U., Turakhozhaev, M.T. (1994) Control of the production of the total iridoids from Ajuga turkestanica. Chem. Nat. Compd. 30:769–770.10.1007/BF00630622Search in Google Scholar

Kozuharova, E., Benbassat, N., Getov, I. (2014) Ethnobotanical records of not yet documented therapeutic effects of some popular Bulgarian medicinal plants. Emir. J. Food Agr. 26:647–651.10.9755/ejfa.v26i7.18200Search in Google Scholar

Kutepova, T.A., Syrov, V.N., Khushbaktova, Z.A., Saatov, Z. (2001) Hypoglycemic activity of the total ecdysteroid extract from Ajuga turkestanica. Pharm. Chem. J. 35:608–609.10.1023/A:1015145811009Search in Google Scholar

Lawrence, B. (1992) Chemical components of Labiate oils and their exploitation. In: Advances in Labiate Science. KEW, R.B.G. Whitstable. pp. 399–436.Search in Google Scholar

Lawrence, M. Ajuga turkestanica as a Countermeasure Against Sarcopenia and Dynapenia. Appalachian State University, Boone, NC, USA, 2012.Search in Google Scholar

Li, B., Olmstead, R.G. (2017) Two new subfamilies in Lamiaceae. 313:5.10.11646/phytotaxa.313.2.9Search in Google Scholar

Li, M.-X., Shang, X.-F., Jia, Z.-P., Zhang, R.-X. (2010) Phytochemical and biological studies of plants from the genus Phlomis. Chem. Biodivers. 7:283–301.10.1002/cbdv.200800136Search in Google Scholar PubMed

Linnaeus, C. (1753) Species Plantarum.Search in Google Scholar

Maksudov, M.S., Maksimov, E.S., Umarova, R.U., Saatov, Z., Abdullaev, N.D. (1995) Phlomoside A – an iridoid glycoside from Phlomis thapsoides. Chem. Nat. Compd. 31:200–202.10.1007/BF01170205Search in Google Scholar

Maksudov, M.S., Maksimov, E.S., Umarova, R.U., Saatov, Z., Abdullaev, N.D. (1996) Phlomoside B – an iridoid glycoside from Phlomis regelii. Chem. Nat. Compd. 32:36–38.10.1007/BF01373786Search in Google Scholar

Mamadalieva, N.Z., Climati, E., Triggiani, D., Ceccarelli, D., Egamberdieva, D., Tiezzi, A. (2010a) In vitro assays to investigate cytotoxic properties of Lamiaceae family plant extracts. Uzbek Biol. J. 7–10.Search in Google Scholar

Mamadalieva, N.Z., Climati, E., Triggiani, D., Ceccarelli, D., Egamberdieva, D., Tiezzi, A. (2010b) Antiproliferative activity of Lamiaceae family plant extracts on murine myeloma cells. Conference “Actual problems of the Chem. Nat. Compd. Tashkent, Uzbekistan.Search in Google Scholar

Mamadalieva, N.Z., Herrmann, F., El-Readi, M.Z., Tahrani, A., Hamoud, R., Egamberdieva, D., Azimova, S.S., Wink, M. (2011) Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activities. J. Pharm. Pharmacol. 63:1346–1357.10.1111/j.2042-7158.2011.01336.xSearch in Google Scholar PubMed

Mamadalieva, N.Z., El-Readi, M.Z., Ovidi, E., Ashour, M.L., Hamoud, R., Sagdullaev, S.S., Azimova, S.S., Tiezzi, A., Wink, M. (2013a) Antiproliferative, antimicrobial and antioxidant activities of the chemical constituents of Ajuga turkestanica. Phytopharmacology 4:1–18.Search in Google Scholar

Mamadalieva, N.Z., Vinciguerra, V., Ovidi, E., Tiezzi, A. (2013b) Identification and isolation of non-polar compounds from the chloroform extract of Scutellaria ramosissima. Nat. Prod. Res. 27:2059–2062.10.1080/14786419.2013.819508Search in Google Scholar PubMed

Mamadalieva, N.Z., Mamedov, N.A., Craker, L.E., Tiezzi, A. (2014a) Ethnobotanical uses and cytotoxic activities of native plants from the Lamiaceae family in Uzbekistan. Acta Horticulturae 61–70.10.17660/ActaHortic.2014.1030.7Search in Google Scholar

Mamadalieva, N.Z., Ovidi, E., Triggiani, D., Yuldasheva, N.K., Ul’chenko, N.T., Glushenkova, A.I., Tiezzi, A. (2014b) Lipid fraction from Scutellaria ramosissima tested on the microtubular array of cancer cell models. Arch. Biomed. Sci. 2:11–17.Search in Google Scholar

Mamadalieva, N.Z., Ovidi, E., Vinciguerra, V., Ashour, M.L., Tiezzi, A. (2014c) Evaluation of biological activities of Thymus seravschanicus and its main compounds. Vestnik 68:25–28.Search in Google Scholar

Mamadalieva, N.Z., Vinciguerra, V., Sobeh, M., Ovidi, E., Ashour, M.L., Wink, M., Tiezzi, A. (2015) GLC-MS profiling of non-polar extracts from Phlomis bucharica and Phlomis salicifolia and their cytotoxicity. Bol. Latinoam. Caribe Pl 14:442–448.Search in Google Scholar

Mamadalieva, N.Z., Ovidi, E., Vinciguerra, V., Ashour, M.L., Azimova, S.S., Tiezzi, A. (2016a) Chemical constituents of Thymus seravschanicus and their biological activities. Chem. Nat. Compd. 52:352–355.10.1007/s10600-016-1643-2Search in Google Scholar

Mamadalieva, N.Z., Bobakulov, K.M., Vinciguerra, V., Tiezzi, A., Abdullaev, N.D., Nahar, L., Azimova, S.S., Sarker, S.D. (2016b) GC-MS and q-NMR based chemotaxonomic evaluation of two Leonurus species. Phytochem. Anal. 27:284–289.10.1002/pca.2629Search in Google Scholar

Mamadalieva, N.Z., Sharopov, F.S., Satyal, P., Azimova, S.S., Wink, M. (2016c) Analysis of the chemical composition of the essential oils of some Central Asian Nepeta species (Lamiaceae) by GLC-MS. Nat. Prod. Commun. 11:1891–1893.10.1177/1934578X1601101229Search in Google Scholar

Mamadalieva, N.Z., Akramov, D.Kh., Ovidi, E., Tiezzi, A., Nahar, L., Azimova, S.S., Sarker, S.D. (2017a) Aromatic medicinal plants of the Lamiaceae family from Uzbekistan: ethnopharmacology, essential oils composition, and biological activities. Medicines 4:1–12.10.3390/medicines4010008Search in Google Scholar

Mamadalieva, N.Z., Sasmakov, S.A., Azimova, S.S. (2017b) Chemical composition, antimicrobial and antioxidant activities of the essential oils of Nepeta cataria and Salvia officinalis from Uzbekistan flora. Uzbekistan Chem. J. 48–53.Search in Google Scholar

Mamadalieva, N.Z., Sharopov, F.S., Satyal, P., Azimova, S.S., Wink, M. (2017c) Composition of the essential oils of three Uzbek Scutellaria species (Lamiaceae) and their antioxidant activities. Nat. Prod. Res. 31:1172–1176.10.1080/14786419.2016.1222383Search in Google Scholar

Mamadalieva, N.Z., Youssef, F.S., Ashour, M.L., Sasmakov, S.A., Azimova, S.S. (2018a) Chemical composition, antimicrobial and antioxidant activities of the essential oils of three Uzbek Lamiaceae species. Nat. Prod. Res. 22:1–4.10.1080/14786419.2018.1443088Search in Google Scholar

Mamadalieva, N.Z., Böhmdorfer, S., Azimova, S.S., Rosenau, T. (2018b) Essential oils compositions and quantification of lamiide in certain Phlomis species. Local scientific-practical conference “Perspectives of the use of natural products in agriculture”. Gulistan, Tashkent. pp. 63–65.Search in Google Scholar

Mamatkhanov, A.U., Yakubova, M.R., Syrov, V.N. (1998) Isolation of turkesterone from the epigeal part of Ajuga turkestanica and its anabolic activity. Chem. Nat. Compd. 34:150–154.10.1007/BF02249133Search in Google Scholar

Mamedov, N., Mamadalieva, N. (2016) Medicinal plants of former USSR used for treatment of depression. In: Herbal Medicine in Depression: Traditional Medicine to Innovative Drug Delivery. Ed. Grosso, C. Springer International Publishing, Basel, Switzerland. pp. 183–258.10.1007/978-3-319-14021-6_6Search in Google Scholar

Naghibi, F., Mosaddegh, M., Motamed, S.M., Ghorbani, A. (2005) Labiatae family in folk medicine in Iran: from ethnobotany to pharmacology. Iran. J. Pharm. Res. 4:63–79.Search in Google Scholar

Neves, J.M., Matos, C., Moutinho, C., Queiroz, G., Gomes, L.R. (2009) Ethnopharmacological notes about ancient uses of medicinal plants in Trás-os-Montes (northern of Portugal). J. Ethnopharmacol. 124:270–283.10.1016/j.jep.2009.04.041Search in Google Scholar

Olimov, M.U, Ganiev, A. (2000) Obtaining a tincture from Phlomis regelii M. Pop and study on its properties in IPORSIP-2000: The Second International Postgraduate Research Symposium on Pharmaceutics, Istanbul University. Istanbul, Turkey: Acta Pharmaceutica Turcica.Search in Google Scholar

Padure, I.M., Mihgiescu, D., Bgdulescu, L., Burzo, I. (2008) Chemical constituents of the essential oils of Nepeta nuda L. ssp. nuda (Lamiaceae) from Romania. Rom. J. Biol. Plant Biol. 53:31–38.Search in Google Scholar

Pulatova, T.P. (1969) Alkaloid content of some plants of the family Labiatae. Chem. Nat. Compd. 5:55–55.10.1007/BF00564937Search in Google Scholar

Rabotyagov, V.D., Aksenov, Y.A. (2014) Component composition of essential oil from species of genus Nepeta L. Farmasiya i farmakologiya. 6:25–28 (in Russian).10.19163/2307-9266-2014-2-6(7)-25-28Search in Google Scholar

Radulović, N., Denić, M., Stojanović-Radić, Z., Skropeta, D. (2012) Fatty and volatile oils of the Gypsywort Lycopus europaeus L. and the Gaussian-like distribution of its wax alkanes. J. Am. Oil Chem.’ Soc. 89:2165–2185.10.1007/s11746-012-2118-7Search in Google Scholar

Raja, R.R. (2012) Medicinally potential plants of Labiatae (Lamiaceae) family: an overview. Res. J. Med. Plants 6:203–213.10.3923/rjmp.2012.203.213Search in Google Scholar

Razzakov, N.A., Tashkhodzhaev, B., Aripova, S.F., Tozhibaev, A.A. (2005) Associate of betonicin with urea from Phlomis regelii. Chem. Nat. Compd. 41:56–59.10.1007/s10600-005-0074-2Search in Google Scholar

Rustaiyan, A., Fard, M.A., Mamadalieva, N.Z. (2016) Constituents and biological activities some of Iranian Nepeta species – review. Eur. J. Pharm. Med. Res. 3:432–435.Search in Google Scholar

Saatov, Z., Agzamkhodzhaeva, D.A., Syrov, V.N. (1999) Distribution of phytoecdysteroids in plants of Uzbekistan and the possibility of using drugs based on them in neurological practice. Chem. Nat. Compd. 35:186–191.10.1007/BF02234932Search in Google Scholar

Sarkar, M., Rashmi, R.V., Varma, P.N. (1995) Pharmacognosy of Nepeta cataria. Anc. Sci. of Life 14:225-234.Search in Google Scholar

Sharma, S.M., Bhadange, D. (2013) Antimicrobial potential of Lamiaceae members. Int. J. Pharm. Pharm. Sci. 3:324–327.Search in Google Scholar

Sharopov, F.S., Setzer, W.N. (2011) Chemical diversity of Ziziphora clinopodioides: Composition of the essential oil of Z. clinopodioides from Tajikistan. Nat. Prod. Commun. 6:695–698.10.1177/1934578X1100600524Search in Google Scholar

Sobeh, M., Mamadalieva, N.Z., Mahmoud, T., Krstin, S., Youssef, F.S., Ashour, M.L., Azimova, S.S., Wink, M. (2016) Chemical profiling of Phlomis thapsoides (Lamiaceae) and in vitro testings of biological activities. Med. Chem. Res. 25:2304–2315.10.1007/s00044-016-1677-9Search in Google Scholar

Sokolov, P. Plant Resources of USSR. Nauka Publ, Sankt Petersburg, 1991.Search in Google Scholar

Syrov, V.N., Khushbaktova, Z.A., Tolibaev, I., Eletskaya, N.V., Mamatkhanov, A.U. (1994) Effect of a lipid concentrate from the aboveground portion of Ajuga turkestanica on the metabolic processes and dynamics of healing skin wounds experimentally. Pharm. Chem. J. 28:837–840.10.1007/BF02218716Search in Google Scholar

Syrov, V.N., Saatov, Z., Sagdullaev, Sh.Sh., Mamatkhanov, A.U. (2001) Study of the structure-activity-anabolic activity relationship for phytoecdysteroids extracted from some plants of Central Asia. Pharm. Chem. J. 35:667–671.10.1023/A:1015344614064Search in Google Scholar

Takeda, Y., Yagi, T., Matsumoto, T., Honda, G., Tabata, M., Fujita, T., Shingu, T., Otsuka, H., Sezik, E., Yesilada, E. (1996) Nepetanudosides and iridoid glucosides having novel stereochemistry from Nepeta nuda ssp. albiflora. Phytochemistry 42:1085–1088.10.1016/0031-9422(96)00074-XSearch in Google Scholar

Todorov, D., Shishkova, K., Dragolova, D., Hinkov, A., Kapchina-Toteva, V., Shishkov, S. (2015) Antiviral activity of medicinal plant Nepeta nuda. Biotechnol. Biotechnol. Equip. 29:S39–S43.10.1080/13102818.2015.1047215Search in Google Scholar

Tulaganova, M. Conspectus florae Asiae MediaeIzdatel’stvo. Akademii Nauk SSSR, Tashkent, 1987. pp. 118–119.Search in Google Scholar

Vvedensky, A. Flora Uzbekistana (Flora of Uzbekistan). Akad. Nauk UzSSR, Tashkent, Uzbekistan, 1961. pp. 266–410.Search in Google Scholar

Waterman, P.G., Gray, A. (1987) Chemical Systematics. Nat. Prod. Rep. 4:175–203.10.1039/np9870400175Search in Google Scholar PubMed

Yuldashev, M.P. (2001) Flavonoids of the aerial part of Scutellaria immaculate. Chem. Nat. Compd. 37:428–430.10.1023/A:1014459023998Search in Google Scholar

Yuldashev, M.P., Karimov, A. (2005) Flavonoids of Scutellaria immaculata roots. Chem. Nat. Compd. 41:32–34.10.1007/s10600-005-0068-0Search in Google Scholar

Yuldashev, M.P., Batirov, É.K., Malikov, V.M. (1992) Flavonoids of the epigeal part of Scutellaria ramosissima. Chem. Nat. Compd. 28:151–154.10.1007/BF00630163Search in Google Scholar

Yuldashev, M.P., Batirov, É.K., Nigmatullaev, A., Malikov, V.M. (1994) Structures of two new flavonoids from Scutellaria ramosissima. Chem. Nat. Compd. 30:324.10.1007/BF00629967Search in Google Scholar

Yulgashev, M.P., Batirov, É.K., Malikov, V.M. (1995) New flavone glycoside from Scutellaria ramosissima. Chem. Nat. Compd. 31:264–265.10.1007/BF01170224Search in Google Scholar

Yuldasheva, N.K., Ul’chenko, N.T., Mamadalieva, N.Z., Glushenkova, A.I., Ovidi, E., Triggiani, D., Tiezzi, A. (2014) Lipids from the aerial parts of Scutellaria ramosissima. Chem. Nat. Compd. 50:68–71.10.1007/s10600-014-0868-1Search in Google Scholar

Zainutdinov, U.N., Khaitboev, K., Khafizov, A.R., Aslanov, K.A. (1994) Method of isolating lagochilin from plants of the genus Lagochilus. Chem. Nat. Compd. 30:129–129.10.1007/BF00638440Search in Google Scholar

Zeichen, R.G.S., Carena, M., Bindstein, E. (2004) Estudió farmacológico comparativo de dos espécies argentinas: Nepeta cataria L. (Labiatae) y Melissa officinalis L. (Labiatae). Boletín Latinoamericano Y del Caribe de Plantas Medicinales y Aromaticas. 3:103–106.Search in Google Scholar

Zubeldia, J.M., Hernández-Santana, A., Jiménez-del-Rio, M., Pérez-López, V., Pérez-Machin, R., Garcia-Castellano, J.M. (2012) In vitro characterization of the efficacy and safety profile of a proprietary Ajuga turkestanica extract. Chin. Med. 3:215–222.10.4236/cm.2012.34031Search in Google Scholar

Received: 2018-12-13
Accepted: 2019-04-09
Published Online: 2019-06-12
Published in Print: 2020-02-25

©2020 Walter de Gruyter GmbH, Berlin/Boston

Downloaded on 9.5.2024 from https://www.degruyter.com/document/doi/10.1515/hf-2018-0296/pdf
Scroll to top button