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Biologically Active Substances in the Aqueous Fraction of Alfredia cernua (L.) Cass. Extract Possessing Antiamnesic Properties

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The composition of biologically active substances in the aqueous total fraction of the 95% EtOH extract of the aerial part of Alfredia cernua (L.) Cass. possessing antiamnesic properties was studied using chromatographic and mass-spectrometric methods. The total amount of N-containing compounds in the fraction was found to be 10.63 ± 1.65%. Fifteen amino acids (1.99 ± 0.11%), seven of which (0.76 ± 0.012%) were essential and included lysine, threonine, valine, isoleucine, leucine, phenylalanine, and histidine, were identified using an amino-acid analyzer. The total fraction was dominated by glutamic and aspartic acids, valine, proline, alanine, and histidine. The composition included a total of 43 elements (1.35 ± 0.1%), of which 19 were essential or conditionally essential. The predominant elements were K, Mg, Zn, Rb, P, Ca, and Mn. Carbohydrates dominated (32 ± 3.1%) the fraction.

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Authors and Affiliations

  1. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, 3 Prosp. Lenina, Tomsk, 634028, Russia

    I. V. Shilova & M. Yu. Minakova

  2. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 1 Partizana Zheleznyaka St., Krasnoyarsk, 660022, Russia

    N. V. Kuvacheva & A. A. Kolmakova

  3. Siberian State University, 79 Svobodnyi Prosp., Krasnoyarsk, 660041, Russia

    V. N. Losev

Authors
  1. I. V. Shilova
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  2. N. V. Kuvacheva
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  3. A. A. Kolmakova
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  4. V. N. Losev
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  5. M. Yu. Minakova
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Correspondence to I. V. Shilova.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 54, No. 12, pp. 29 – 32, December, 2020.

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Shilova, I.V., Kuvacheva, N.V., Kolmakova, A.A. et al. Biologically Active Substances in the Aqueous Fraction of Alfredia cernua (L.) Cass. Extract Possessing Antiamnesic Properties. Pharm Chem J 54, 1239–1242 (2021). https://doi.org/10.1007/s11094-021-02349-5

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  • DOI: https://doi.org/10.1007/s11094-021-02349-5

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