WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H581060
CAS#: 1422355-65-4
Description: GSK2565363C is agent betulin derivative, it as antitumor. Acetylenic derivative of betulin induces apoptosis in endometrial adenocarcinoma cell line.
Hodoodo Cat#: H581060
Name: GSK2565363C
CAS#: 1422355-65-4
Chemical Formula: C48H71ClN2O6
Exact Mass: 806.50
Molecular Weight: 807.550
Elemental Analysis: C, 71.39; H, 8.86; Cl, 4.39; N, 3.47; O, 11.89
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Synonym: GSK2565363C; 4-[[(3aR,5aR,5bR,7aS,11aR,11bS,13aS)-3a-[2-[(4-Chlorophenyl)methyl-[2-(dimethylamino)ethyl]amino]acetyl]-5a,5b,8,8,11a-pentamethyl-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3H-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid
IUPAC/Chemical Name: 4-[[(3aR,5aR,5bR,7aS,11aR,11bS,13aS)-3a-[2-[(4-Chlorophenyl)methyl-[2-(dimethylamino)ethyl]amino]acetyl]-5a,5b,8,8,11a-pentamethyl-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3H-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid
InChi Key: CVSNBOABZIJTLI-ZCDBIZOMSA-N
InChi Code: InChI=1S/C48H71ClN2O6/c1-30(2)40-34(52)26-48(37(53)29-51(25-24-50(10)11)28-31-12-14-32(49)15-13-31)23-22-46(8)33(41(40)48)16-17-36-45(7)20-19-38(57-39(54)27-43(3,4)42(55)56)44(5,6)35(45)18-21-47(36,46)9/h12-15,30,33,35-36,38H,16-29H2,1-11H3,(H,55,56)/t33-,35-,36+,38?,45+,46-,47-,48+/m1/s1
SMILES Code: O=C(O)C(C)(C)CC(OC(CC[C@]1(C)[C@]2([H])CC[C@@]34[H])C(C)(C)[C@@]1([H])CC[C@@]2(C)[C@]3(C)CC[C@]5(C(CN(CC6=CC=C(Cl)C=C6)CCN(C)C)=O)C4=C(C(C)C)C(C5)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 807.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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