Crude drug sample data base
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Crude drug name | Market name | Dhaturo |
|---|---|---|
| Formal name | Krsnadhattura | |
Other names Tips！ | Dhatura (B), Dhatura (H), Ummatta (M), Dhaturo, Seto dhaturo (N) | |
| English name | Jimson Weed, Stink Weed, Mad Apple, Thorn Apple, Stramonium | |
| Original plant name | Datura stramonium L. (= Datura tatula Linn.), Jimson Weed, Stink Weed, Mad Apple, Thorn Apple, Stramonium | |
| Family name | Solanaceae | |
| Used part | Classification | Plant origin | Sub classification | fruit |
| Collection information | Kingdom of Nepal, Jumla | |
| Collection date | 1998/10/5 | |
| Collector | Tsuneo Namba | |
| TMPW No. | 22850 | |
Scientific information data base
| Crude drug name | Ayurvedic name or Sanskrit name, English name | Krsnadhattura, Jimson Weed, Stink Weed, Mad Apple, Thorn Apple, Stramonium | ||
|---|---|---|---|---|
| Synonyms | Devika, Dhurta, Dhurtakrt, Dhustura, Dutturapatra, Gantapuspa, Ghantika, Haravallabha, Kahalapuspa, Kalama, Kanaka, Kantaphala, Khala, Karadusana, Karhughna, Kitava, Krsnadhattura, Madakara, Madana, Madanaka, Mahamohi, Mahasatha, Matta, Matula, Matulaka, Mohana, Rajadhattura, Savisa, Saiva, Satha, Sivapriya, Sivasekhara, Syama, Turi, Unmatta, Unmattaka. | |||
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| Original plant name | Datura stramonium Linn. (= Datura tatula Linn.) | |||
| Family name | Solanaceae | |||
| Used part | Seeds | |||
| Distribution area | The plant is distributed on the hills throughout India upto an altitude of 8,000 ft. and is common in north-western Himalayas. | |||
| Remarks | Common. | |||
| Common uses | Datura consists of dried leaves and flowering tops of D. stramonium. It has a characteristic disagreeable odour and a bitter unpleasant taste. Datura is similar to belladonna in the symptoms produced by it, and in its general physiological and therapeutic action. It is a narcotic, antispasmodic and anodyne, and is used chiefly to relieve the spasm of the bronchioles in asthma. Leaves may be made into cigarettes or smoked in a pipe, with or without tobacco, to relieve asthma. They are also used in the treatment of parkinsonism. Leaves are applied to boils, sores and fish bites and the juice of the flowers is used for earache. Datura is administered in pills, tablets, tinctures and extracts. Datura ointment, containing lanolin, yellow wax and petrolatum, is employed in the treatment of haemorrhoids/hemorrhoids. The juice expressed from the fruits is applied to the scalp for curing dandruff and falling hair. | |||
| Chemical constituent | Flavones & Flavonols 3,5,7,3’,4’-Pentahydroxyflavone (*C2, *C3), 5,7,3’,4’-Tetrahydroxyflavone 3-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside (*C2), 3,5,3’,4’-Tetrahydroxyflavone 7-O-beta-D-glucopyranoside (*C2), 5,7-Dihydroxyflavone (*C3), 3,5,7,4’-Tetrahydroxyflavone (*C3) Phenol derivatives 2,6-Dichlorophenol (*C4) Tropane alkaloids 3-(3’-acetoxytropoyloxy)Tropane (*C1), 3-(2-hydroxytropoyloxy)Tropane (*C1), | |||
| Pharmacological effect | It annuls the action of acetyl choline and thus produces the effects of paralysis on the peripheral ends of the vagi in the bronchioles so that the latter relax. It is used in doses of 0.15g., 3 times a day, increased to 1g. Daily to control salivation and muscular spasms and tremor which follow encephalitis lethargica. | |||
| Medical system | Ayurveda (Traditional Indian medicine) | |||
| Related drugs | Leaves of Datura innoxia and D. metel are used as substitutes for D. stramonium and those of Xanthium strumarium L., Carthamus helenioides Desf. and Chenopodium hybridum L. are used as adulterants. | |||
| Comments | It is said to be one of the varieties of Dhattura described in Rajanighantu. It is considered to be Rajadhattura in Nighantu adarsa. | |||
| References | Reference book Tips！ | Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi p 220. Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore 52. Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi Vol. 2, p 501. | ||
| Research paper | *C1 Philipov, S. and Berkov. S., Zeitschriff fuer Naturforschung, C: J. Bio. Sci., 57, 559-61 (2002). *C2 Pate, D. W. and Averett, J.; Biochem. Syst. Ecol., 14, 647-49 (1986). *C3 Lakshmi, S. and Krishnamoorthy, T. V., Indian J. Pharm. Sci., 53, 94-95 (1991). *C4 Seetharam, Y. N., Murthy, N. S. and Vijay; Asian J. Chem., 13, 768-70 (2001). | |||
| Remarks | Seeds have large amount (16-17%) of fixed oil, and have been employed for suicidal and homicidal purposes. These names are applied to Datura irrespective of the species. The equivalents for 'white' or 'black' in different vernaculars are usually prefixed to distinguish plants bearing white flowers from those bearing tinted flowers. The flower color is not a characteristic of the species and plants of the same species may bear white, purplish or violet flowers. | |||
| Last renewal date | 2022/06/20 | |||
